Oral solid pharmaceutical composition, preparation method therefor, and use thereof
By optimizing the formulation and process of onradivir, especially by using internal and external addition of fillers, the disintegration and dissolution problems of onradivir have been solved, achieving high bioavailability and stable formulation effects, making it suitable for the treatment of influenza A.
WO2026119226A1PCT designated stage Publication Date: 2026-06-11GUANGDONG RAYNOVENT BIOTECH CO LTD
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- GUANGDONG RAYNOVENT BIOTECH CO LTD
- Filing Date
- 2025-12-04
- Publication Date
- 2026-06-11
Smart Images
Figure PCTCN2025139932-FTAPPB-I100001 
Figure PCTCN2025139932-FTAPPB-I100002 
Figure PCTCN2025139932-FTAPPB-I100003
Abstract
The present invention provides an oral solid pharmaceutical composition, comprising onradivir as an active ingredient, an alkaline reagent, and a solubilizer, and further comprising a filler. The oral solid pharmaceutical composition of the present invention effectively improves the solubility of onradivir, improves the bioavailability of onradivir in the human body, and can solve formulation issues, such as the issue where effective disintegration cannot be achieved by means of conventional formulas and processes, which is conducive to achieving the clinical application of onradivir.
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