Efficient and stable cis-isomerization method for lycopene

By using a bimetallic organic framework material and confined water molecules for synergistic catalysis, the problem of low cis-isomerization efficiency of lycopene was solved, achieving a highly efficient and stable isomerization effect and improving the selectivity and retention rate of the product.

WO2026124395A1 Publication Date: 2026-06-18CHINA PHARM UNIV
0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
CHINA PHARM UNIV
Filing Date
2025-12-08
Publication Date
2026-06-18

AI Technical Summary

⚠Technical Problem

Existing methods for cis-isomerization of lycopene are inefficient and unstable, and conventional methods lead to product degradation, making it difficult to achieve highly selective and efficient isomerization.

⚗Method used

A bimetallic organic framework material was used as a catalyst. The catalyst formed by zirconium-based organic framework material and transition metal ion doping was combined with confined water molecules as a catalytic medium. The cis-isomerization of lycopene was carried out by heating in a hot reflux water bath.

🎯Benefits of technology

The method improved the cis-isomerization efficiency of lycopene to 82.2% and the retention rate to 90.3%, which is significantly better than existing technologies, and the method is green and environmentally friendly.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Disclosed in the present invention is an efficient and stable cis-isomerization method for lycopene. The method comprises using a bimetallic metal-organic framework material as a catalyst to catalyze the cis-isomerization of lycopene. In the method, confined water molecules can also be added to a reaction system as a catalytic medium to efficiently catalyze the isomerization of lycopene. The catalyst attacks and activates a conjugated double bond of all-trans-lycopene in an electron-rich environment, leading to rotation to form a corresponding configuration, and the confined water molecules serve as an electron transfer medium to accelerate the ability of the trans-lycopene to lose electrons, forming a lycopene free radical as an isomerization intermediate product, and further improving the isomerization yield of cis-lycopene. The method is green and efficient, increasing the isomerization efficiency of cis-lycopene up to 82.2%, and under the process condition, lycopene has a higher retention rate of 90.3%. The method is green and efficient and has great prospects for application.
Need to check novelty before this filing date? Find Prior Art