Stimulation modes for disordered breathing therapy
An implantable system with adaptive nerve stimulation adjusts to respiratory changes, effectively managing disordered breathing by coordinating phrenic and upper-airway nerve stimulation to improve breathing patterns and reduce apnea events.
WO2026136017A1PCT designated stage Publication Date: 2026-06-25ZOLL MEDICAL CORPORATION
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- ZOLL MEDICAL CORPORATION
- Filing Date
- 2025-12-05
- Publication Date
- 2026-06-25
AI Technical Summary
Technical Problem
Existing treatments for disordered breathing, such as sleep apnea, are inadequate in effectively managing respiratory reductions and transitions between different breathing states.
Method used
An implantable treatment system with principal and subordinate stimulation circuitry for phrenic and upper-airway nerve electrical stimulation, controlled by an IPG, dynamically adjusts stimulation modes based on respiration sensor feedback to address respiratory reductions.
Benefits of technology
The system effectively manages respiratory reductions by coordinating phrenic and upper-airway nerve stimulation, improving breathing patterns and reducing apnea events through adaptive control strategies.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure US2025058288_25062026_PF_FP_ABST
Abstract
Examples of the disclosure include an implantable system comprising principal stimulation circuitry configured to provide electrical stimulation to a phrenic nerve via at least one phrenic nerve stimulation electrode, subordinate stimulation circuitry configured to provide electrical stimulation to an upper-airway nerve via at least one upper-airway-nerve stimulation electrode, at least one respiration sensor, and an implantable pulse generator (IPG) comprising the stimulation circuitries and at least one processor configured to cause the subordinate stimulation circuitry to deliver stimulation in an absence of delivery of the phrenic nerve stimulation, monitor a signal from the respiration sensor(s), identify a respiration reduction based on the signal during the stimulation delivery, and in response thereto, cause the stimulation circuitries to deliver the stimulations concurrently based in part on the respiration signal and control a timing of delivery of the upper- airway-nerve electrical stimulation relative to a timing of delivery of the phrenic nerve electrical stimulation.
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