Portable RO-device configured for isolated stand-by

Abstract

The present invention pertains to a portable Reverse Osmosis-device that can enter an isolated standby-mode in that the device is fluidically separated from the outside awaiting is next use quicker than conventional Reverse Osmosis-devices. This is achieved by the fact that the time-consuming initial heat disinfection of the device is effected with the device already being fluidically isolated from the outside. In other words, the extensive initial heat disinfection of the device is already part of the isolated standby mode and does not have to be performed before the device can be fluidically isolated from the outside. This significantly saves time of medical personnel. A further improvement is that during the isolated standby mode, sterility of the device is maintained by performing a shorter, reduced heat disinfection at regular intervals. This shorter heat disinfection saves energy and reduces wear of the Reverse Osmosis-device, in particular the membrane module.

Description

[0001] 02899-25 He

[0002] Fresenius Medical Care GmbH

[0003] Bad Homburg, Germany

[0004] &

[0005] Fresenius Medical Care North America

[0006] Waltham, MA, USA

[0007] Portable RO-device configured for isolated stand-by

[0008] Reverse-Osmosis devices (RO-devices) are known devices useful for producing pure water, e.g. for medical applications.

[0009] RO-devices generally come in two varieties: large, stationary RO-Devices used, e.g. in dialysis centers, and portable, mobile RO-devices that can flexibly be moved from a storage location to a point-of-care on demand.

[0010] The present invention pertains to a portable RO-device. When portable RO-devices are not in active use, they are usually fluidically and electrically disconnected from the outside and placed into storage.

[0011] To ensure a rapid usability of the RO-devices upon demand, the portable RO-devices enter a standby mode that allows the RO-devices to rapidly be taken out of storage and be reconnected to water and electricity supplies to start operating.In practice, however, getting a portable RO-device ready for storage, i.e. putting the device into the required isolated standby mode, requires several steps to be supervised by medical personnel and thus is rather time consuming.

[0012] A particular disadvantage of the prior art is that an extensive heat disinfection of the RO-device has to be performed before the device can be fluidically disconnected from the outside (e.g. the water supply and drain lines are disconnected) and placed into storage.

[0013] The need for the heat disinfection prior to the fluidical disconnection of the device form the outside means in practice, that it takes ca. 4 hours for the RO-device to be ready to be placed into storage.

[0014] Thus, after initiating the isolated standby mode, personnel have to wait ca. 4 hours before placing the RO-devices into storage. This disrupts workflows and is a significant burden on medical personnel.

[0015] Against this background, the present invention strives to reduce or even completely eliminate the disadvantages of the prior art.

[0016] One specific technical objective of the present invention is to develop a way of improving a RO-device to enter an isolated standby mode in a more convenient way.

[0017] This objective is achieved by the subject matter of the independent claims. Advantageous embodiments of the invention are the subject of the dependent claims.

[0018] Accordingly, a portable Reverse Osmosis- device (RO-device) is provided, comprising a water supply section, a water tank, a reverse osmosis membrane module, a permeate collection line, a retentate line and a control unit, wherein the Reverse Osmosis- device is configured to be operable in an isolated standby mode in that the Reverse Osmosis- device is fluidically separated from the outside.In the context of the present disclosure, the term “portable” preferably means that the RO-device can be moved or carried by a single person or two people and preferably is equipped with wheels easily to allow the device to be moved around.

[0019] A portable RO-device according to the invention is preferably configured to be moved about, which can also be reflected in the hydraulic layout, such that e.g. connection ports of the RO-device to connect e.g. to a water supply, retentate drain or to a permeate consumer can be equipped with sealing structures or lids that allow the connection ports to be closed off during storage to avoid contamination.

[0020] In the context of the present disclosure, the term “Isolated standby mode” preferably means an operation state of the RO-device in that the RO-device is fluidically and I or electrically disconnected from the outside.

[0021] Most often, the RO-device is only fluidically disconnected from the outside, but still connected to an electricity supply.

[0022] However, it is in principle possible to also electrically disconnect the RO-device from the outside, in this case, the RO-device needs to be equipped with an energy storage device, such as a battery.

[0023] In the isolated standby mode, the RO-device preferably maintains operability and sterility on its own accord via a corresponding control effected by the control unit of the device, so that the RO-device can rapidly be returned to an operation to provide medical grade water.

[0024] In other words, the RO-device is not shut down during the isolated standby mode, but also does not require user attention during the isolated standby mode.In a portable Reverse Osmosis- device according to the present invention, the control unit can be configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, a first heat disinfection mode and a second heat disinfection mode, wherein the first heat disinfection mode preferably takes a longer time to complete than the second heat disinfection mode. The first heat disinfection mode for example takes a longer time than the second heat disinfection mode, preferably between 4 to 6 times longer, in particular 5 times longer.

[0025] Contrary to conventional RO-devices of the prior art, according to this aspect of the present invention, the first heat disinfection mode is preferably performed when the RO-device has already entered the isolated standby mode (i.e. is fluidically disconnected from the outside) and not prior to entering the isolated standby mode as known in the prior art.

[0026] This has the advantageous effect that medical personnel does not have to wait until the first heat disinfection mode (which can take up to 4 hours) is completed before fluidically disconnecting the RO-device from the outside and placing it into storage.

[0027] Medical personnel can immediately after fluidically disconnecting the RO-device from the outside place the RO-device into storage and the RO-device then, already in its final storage position, performs the first heat disinfection mode on its own without requiring user attention.

[0028] This increases flexibility in the work flow of the user or medical personnel.

[0029] A portable RO- device according to the present invention is preferably equipped with a water tank to store the water required for any heat disinfection modes effected during the isolated standby mode.

[0030] The water tank can have a volume of between 10 L and 50 L and can be equipped with at least one filling level sensor or multiple filling level sensors. For example, threefilling levels sensors can be provided indicating a low fill level, full fill level and overly full fill level.

[0031] During an initial rinsing step of the RO-device prior to entering the isolated standby mode, the control unit of the device can effect a control such that the water tank is filled with water up to the “full” fill level.

[0032] The RO device then has sufficient water reserves to stay in the isolated standby mode for e.g. a maximum of 30 days.

[0033] In a portable Reverse Osmosis- device according to the invention, the control unit can be configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, as the first heat disinfection mode a heat module disinfection in that more components of the reverse-osmosis device, preferably including the reverse osmosis membrane module, are disinfected by heat, than in the second heat disinfection mode. The first heat disinfection mode can run for 1 to 4 hours.

[0034] In the first heat disinfection mode, for example a dialysis water section (e.g. a ring line and I or other circuitry used to conduct dialysis water) and a rententate section (e.g. circuitry used to conduct or circulate retentate) can be disinfected by heat.

[0035] As this first heat disinfection mode is preferably performed with the RO-device already fluidically disconnected from the outside and placed into storage, the long duration of the heat disinfection does not burden the user.

[0036] In a portable Reverse Osmosis- device according to the invention, the control unit can be configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, as a second heat disinfection mode a ring heat disinfection in that for example only the dialysis water section of the Reverse-Osmosis device is disinfected.The components of the RO-device disinfected in the second heat disinfection mode preferably comprise a ring line for connecting the reverse osmosis device to a permeate consumer, optionally at least one valve, optionally at least one pump and further optionally the permeate side of the reverse osmosis membrane module. The second heat disinfection mode preferably runs for 5 to 20 minutes.

[0037] In other words, the control unit of a RO-device according to the present invention can be configured to perform a “large” first heat disinfection mode and a “small” second disinfection mode.

[0038] Both of these heat disinfection modes are preferably effected with the RO-device already having entered the isolated standby mode and being flu idical ly disconnected from the outside.

[0039] The first heat disinfection mode can be effected by the control unit initially as a fist heat disinfection mode upon the RO-device entering the isolated standby mode. The first heat disinfection mode ensures an extensive, deep heat disinfection of the entire RO-device.

[0040] During the isolated standby mode, the control unit can repeatedly effect the second heat disinfection mode to maintain sterility of the RO-device.

[0041] Because in the isolated standby mode, the RO-device is fluidical ly disconnected from the outside, contaminations are less likely and thus it can suffice to heat disinfect only part of the RO-device, such as the ring line used to connect the RO-device to a permeate consumer (e.g. a dialysis device).

[0042] In other words, during the isolated standby mode, the control unit can be configured to repeatedly perform only the second heat disinfection mode and not the first heat disinfection mode to effect only as extensive an heat disinfection as is actually required.This saves energy and also reduces wear of the RO-device, in particular of the RO-membrane module, that can be damaged by repeated heat disinfection. The longevity of the RO-device is thus improved.

[0043] Thus, the control unit can be configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, at first at least once the first heat disinfection mode followed by repeated performances of the second heat disinfection mode until the isolated standby mode is ended, preferably a maximum of 30 days after the isolated standby mode has been entered by the Reverse-Osmosis device.

[0044] The control unit is preferably configured to perform the first and second heat disinfection modes on its own accord after having received an instruction to enter the RO-device into the isolated standby mode, so that the RO-device does not require user attention in the isolated standby mode.

[0045] The control unit can be configured to perform the second heat disinfection mode at regular intervals, preferably once daily, until the isolated standby mode is ended. The intervals can be set e.g. by a user.

[0046] To further ensure internal sterility of the RO-device during the isolated standby mode, the control unit can be configured to effect, in a state in that the Reverse Osmosisdevice is operated in the isolated standby mode, a circulation step in that water is circulated within the Reverse Osmosis- device, wherein the circulation step is preferably performed at regular intervals, in particular every 3-5 hours, preferably every 4 hours.

[0047] The circulation of water through the hydraulic set-up of the RO-device hampers bacterial growth and thus prevents contamination of the device.The control unit can further be configured to effect an initial rinsing step prior to entering the reverse osmosis device into the isolated standby mode, wherein during the initial rinsing step the Reverse Osmosis-device is preferably rinsed with water at a flow rate of between 0.8 L / min to 1.3 L / min and a volume of between 5 L and 75 L.

[0048] During the initial rinsing step, the RO-device is preferably still fluidically connected to the outside.

[0049] As described above, the initial rinsing step can be used to fill the water tank of the RO-device to a desired fill level, so the RO-device is autonomous regarding water supply during the isolated standby mode.

[0050] The control unit can be configured to, after the instruction to enter the Reverse-Osmosis device into the isolated standby mode has been received by the control unit, perform only the initial rinsing step prior to the fluidical separation of the Reverse-Osmosis device from the outside without the need for a decalcification step and I or heat disinfection step prior to the fluidical separation of the Reverse-Osmosis device from the outside.

[0051] This distinguishes the control unit of a RO-device according to the present invention from conventional solutions according to that prior to fluidically separation of the RO-device from the outside, the control unit would have to perform a decalcification and I or (first) heat disinfection mode.

[0052] As discussed above, it is an advantage of the present invention, that an RO-device according to the present invention can enter the isolated standby mode and thus be placed into storage more quickly than conventional RO-devices. This is achieved at least in part by the configuration of the control unit of the RO-device.After the instruction to enter the Reverse-Osmosis device into the isolated standby mode has been received by the control unit, the control unit of an RO-device according to the present invention can be configured to effect a control such that the Reverse Osmosis- device is in the isolated standby mode 15 minutes to 1 hour after the receipt of the instruction to enter the Reverse-Osmosis device into the isolated standby mode by the control unit.

[0053] This is significantly shorter than the ca. 4-5 hours required by a conventional RO-device to enter the isolated standby mode after the receipt of the instruction to enter the Reverse-Osmosis device into the isolated standby mode by the control unit.

[0054] When the isolated standby mode is to be ended, preferably the control unit, after having received an instruction to exit the isolated standby mode, is configured to instruct a user to fluidically reconnect the Reverse Osmosis- device to a water supply and drain line.

[0055] The control unit then preferably effects on its own accord the steps required to get the RO- device ready for the production of medical grade water, in particular dialysis water.

[0056] The control unit can be configured to effect, after having received an instruction to exit the isolated standby mode, a device test to check the function of the Reverse Osmosis- device, and preferably, after the device test, effect a rinsing step in that preferably the entire Reverse Osmosis- device is rinsed with a volume of water between 45 L and 55 L at a flow rate of between 0.8 L / min to 1 .3 L / min. The device test can be a T1 -test.

[0057] The RO-device is then ready for active use.

[0058] A Reverse Osmosis- device according to the present invention preferably is portable and / or movable by a single person or two people and preferably is equipped withwheels. A Reverse Osmosis- device according to the present invention preferably has the size of a tower PC.

[0059] A Reverse Osmosis- device according to the present invention is preferably configured to provide medical grade water, preferably dialysis water.

[0060] Another aspect of the present invention pertains to a system comprising at least one portable Reverse Osmosis- device according to the present invention and at least one permeate consumer, preferably a dialysis device, fluidically coupled to the Reverse Osmosis- device.

[0061] In a system according to the present invention, at least two dialysis devices can be fluidically coupled to the at least one portable Reverse Osmosis- device.

[0062] Furthermore, another aspect of the present inventions pertains to a method of entering an RO-device into an isolated standby mode.

[0063] Such a method can comprise at least a subset of the steps disclosed above in the context of the control unit of an RO-device at the present invention and I or at least a subset of the steps disclosed in Fig. 2.

[0064] It should be understood that these steps may also be claimed in the framework of a method claim, even if they are not explicitly outlined in this format in the present disclosure to avoid redundancies.

[0065] In a preferred embodiment of the invention with the first heat disinfecting mode including the reverse osmosis membrane module and the second heat disinfection mode only including the permeate side of the reverse osmosis membrane module, hot water is pressed trough the membrane surface, permeating the membrane sheet, only in the first but not in the second heat disinfection mode. This beneficially allowsfurther reducing the wear of the membrane by the second heat disinfection mode and of the RO.

[0066] At this point, it should be noted that the terms ‘a’ and ‘an’ do not necessarily refer to exactly one of the elements, although this is a possible version, but can also refer to a plurality of the elements. Similarly, the use of the plural also includes the presence of the element in question in the singular and, conversely, the singular also includes several of the elements in question.

[0067] Furthermore, all of the features of the invention described herein may be combined with one another or claimed in isolation from one another as desired.

[0068] Further advantages, features and effects of the present invention are apparent from the following description of preferred embodiments with reference to the figures. In the figures,

[0069] Fig. 1 illustrates a hydraulic layout of a Reverse-Osmosis device according to the present invention; and

[0070] Fig. 2 illustrates an exemplary control logic than can be performed by a control unit of a Reverse-Osmosis device according to the present invention.

[0071] As shown in Fig. 1 , a portable Reverse Osmosis- device according to the present invention comprises a housing H, a water supply 1 , a water tank 2, a reverse osmosis membrane module M1, a permeate collection line 3, a retentate line 4 and a control unit (not shown). The water supply 1 connects e.g. to a municipal water supply.

[0072] The retentate line 4 conducts retentate (preferably, water that has not penetrated the membrane of the membrane module M1 ) from the membrane module M1 to the water tank 2. In the retentate line 4, there is a pump p1 for driving water flow.The circuitry from the water tank 2 through the retentate line 4, the membrane module M1 and back to the water tank 2 is an example of a retentate section of the RO-device that is heat disinfected e.g. during the first heat disinfection mode.

[0073] The device is connected to the drain via two connectors 5 and 6. The connector 5 is part of a pressurized drain line and the connector 6 is part of a drain by gravity.

[0074] The device can supply dialysis water via a connector 7 that can be coupled to a permeate consumer, such as a dialysis device. Also, samples of the dialysis water can be taken via the connector 7 for quality control.

[0075] If the RO-device is not actively supplying dialysis water, the connector 7 can be closed off by a bypass-line. Also, the valve VR24 can be opened, so that the ring line 8 is short-circuited.

[0076] The connector 7 is part of a ring line 8 that forms a circuit from the valve V41 to the connector 7 and back. In the ring line 8, there is a pump p2 suitable for circulation of fluid in the ring line 8.

[0077] This circuit is an example of a dialysis water section of the RO-device that is heat disinfected e.g. during the first heat disinfection mode and the second heat disinfection mode.

[0078] The dialysis water section can be defined more broadly as that circuitry of the RO-device conducting only or at least partially dialysis water I permeate produced by the RO-device.

[0079] In other words, during the second heat disinfection mode, i.e. the “small” heat disinfection, preferably only this ring line 8 and its components, such as the permeate side of the membrane module M1 , are heat disinfected. In other words, the dialysis water section is heat disinfected by the second heat disinfection mode.During the first heat disinfection mode, i.e. the “large” heat disinfection, preferably the dialysis water section of the RO-device is disinfected (like in the second heat disinfection mode) and additionally, also the retentate section and I or the drain lines leading to the drain connectors 5 and 6 are also heat disinfected.

[0080] The retentate section can be defined more broadly as that circuitry of the RO-device conducting only or at least partially retentate repelled by the membrane of the membrane module M1 of the RO-device.

[0081] The device further comprises a pump p1 suitable for circulation of fluid in the renten-tate line 4.

[0082] The section of the RO-device from the water supply 1 (e.g. a municipial water supply) to the water tank 2 is an example of a water supply section of the RO-device.

[0083] The water supply section is generally not heat disinfected, neither in the first heat disinfection mode, nor in the second heat disinfection mode.

[0084] The tank 2 is equipped with four fill level sensors, L1- to L4, arranged at different heights of the tank. The control unit can detect the fill level of the tank 2 via the sensors L1 to L4. In principle, only one fill level sensor can suffice.

[0085] The terms “dialysis water” and “permeate” are preferably used synonymously and indicate water than has been purified by the reverse osmosis membrane module M1 of an RO-device according to the present invention.

[0086] The term “retentate” preferably means that fraction of the feed water provided by the water supply 1 that does not permeate the membrane of the reverse osmosis membrane module M1.When the reverse osmosis device of Fig. 1 is in the isolated standby mode, the water supply 1 , the drain connectors 5 and 6 and the connector 7 are disconnected and the device is thus fluidically separated from the outside.

[0087] The water supply 1 , the drain connectors 5 and 6 and the connector 7 can optionally be sealed e.g. by lids or plugs to reduce the risk of contamination.

[0088] During the isolated standby mode, the control unit can effect a circulation step in that water is circulated in the ring line 8 and I or the retentate line 4 to hamper bacterial growth.

[0089] Fig.2 illustrates an exemplary control logic than can be performed by a control unit of a Reverse-Osmosis device according to the present invention.

[0090] This control logic is only an example, however, and shall not be construed to limit the invention.

[0091] A control unit of a Reverse-Osmosis device according to the present invention can be configured to perform at least one of the steps shown in Fig. 2 or a desirable subset of these steps.

[0092] In the flow chart of Fig. 2, steps S1 to S14 are part of a starting sequence, steps S15 to S20 are part of the actual isolated standby mode with the RO device being arranged e.g. in storage, and steps S21 to S26 are part of an end sequence in that the RO device is woken up again from the isolated standby mode and made ready for active use, i.e. the production of permeate.

[0093] Step S1 is the start point of the control logic.

[0094] In step S2, the RO device issues a user prompt via a user interface to ask the user to start an isolated standby mode or not.In step S3, the RO device issues a user prompt via a user interface to ask the user whether the user would like to perform a first heat disinfection mode prior to disconnecting the water supply and drain of the RO device to thereby fluidically separate the RO device from the outside.

[0095] In other words, in step S3 the user is asked whether the user wishes to perform a first heat disinfection mode prior to fluidically separating the RO device from the outside (step S10) or after separating the RO device from the outside (step S18).

[0096] In the latter case, the first heat disinfection mode is performed in the isolated standby mode, in step S18.

[0097] If the user selects No in step S3, the logic proceeds to step S 11. If the user elects Yes, then the logic proceeds to step S4.

[0098] In step S4, the control unit of the RO-device checks whether the water hardness has been adjusted to > 1° dH. If no, the control logic proceeds to step S10. If yes, the control logic proceeds to step S5.

[0099] In step S5, the RO device issues a user prompt via a user interface to ask the user to start a first heat disinfection mode.

[0100] If the user elects Yes in step S5, in step S6 the RO device issues a user prompt via a user interface to ask the user whether the user wants to perform a decalcification mode prior to the first heat disinfection mode.

[0101] The user can elect between two user prompts, e.g. “Perform Decalcification” in step S7 and “Skip decalcification” in step S8.

[0102] If the user elects “Perform Decalcification” in step S8, the control unit effects a decalcification mode in step S9. Decalcification runs for ca 2- 2.5 hours.After that, the control unit puts the RO device into the first heat disinfection mode in step S10. The first heat disinfection mode runs for ca 1 -1.5 hours.

[0103] After the first heat disinfection mode in step S10 has been concluded, the control unit performs an initial rinsing step S11 in that the RO-device is rinsed with a volume of water between 1 L and 50 L at a flow rate of between 0.8 L / min and 1.2 L / min.

[0104] The initial rinsing step S11 is “initial”, because the prior first heat disinfection mode in step S10 is optional and may be omitted.

[0105] In step S12, the control unit can perform a device test to validate the functionality of the RO-device.

[0106] In step S13, the control unit issues a user prompt via a user interface to ask the user to flu idical ly separate the RO-device from the outside, e.g. by disconnecting the water supply and drain.

[0107] In step S14, the user fluidically separates the RO device from the outside, e.g. by disconnecting the water supply and drain. The RO device can now be brought to its storage location.

[0108] In step S15, the control unit issues a user prompt via a user interface to ask the user to confirm that the RO device has been fluidically separated from the outside and that the isolated standby mode should be entered.

[0109] In step S16, the user confirms the fluidical separation of the RO device and in step S17 the control unit enters the RO device into the isolated standby mode.

[0110] In step S18, the control unit enters the RO device into the first heat disinfection mode, if no first heat disinfection mode has been effected in step S10.In other words, a first heat disinfection mode is preferably effected either in step S10 or in step S18.

[0111] After the first heat disinfection mode has been finished, the control unit in step S19 performs a circulation step for between 2 and 10 minutes, preferably 5 minutes, in that water is circulated within the RO-device to hamper bacterial growth. '

[0112] The circulation step S19 is preferably repeated at regular intervals, e.g. between every 2 to 6 hours, preferably every 4 hours, until the isolated standby mode is ended.

[0113] In step S20, the control unit further performs a second heat disinfection mode that disinfects only part of the RO-device, e.g. the ring line 8.

[0114] The second heat disinfection mode of step S20 can last between 7 and 15 minutes, preferably 12 minutes, and the water employed can reach temperatures between 80 °C and 99°C, preferably about 88 °C.

[0115] The second heat disinfection mode S20 is preferably repeated at regular intervals, e.g. once or twice daily, until the isolated standby mode is ended.

[0116] The RO-device can be maintained in the isolated standby mode in this way for up to 30 days.

[0117] In step S21 , the control unit issues a user prompt via a user interface to ask the user to confirm that the isolated standby mode is to be ended.

[0118] After the user has confirmed in step S21 that the isolated standby mode should be ended, the user then, e.g. after having carried the RO device from the storage location to a point-of-care, in step S22 flu idical ly reconnects the RO device to the outside, e.g. by reconnecting the water supply and drain line(s).In step S23, the control unit issues a user prompt via a user interface to ask the user to confirm that the RO-device has been reconnected. For example, the user can press an “Enter” key.

[0119] In step S24, the control unit then performs a device test to validate the functionality of the RO-device that the RO device is capable of producing ultrapure water.

[0120] After the device test, the control unit can further effect a rinsing step in step S25, in that the RO device is preferably completely rinsed, e.g. with a volume of water between 45 L and 55 L, preferably 50 L at a flow rate of between 0.8 L / min and 1.2 L / min, preferably a flow rate of 0.9 L / min.

[0121] In step S26 then RO device then enters a standby mode and is ready for active use.

[0122] This standby mode is different from the “isolated standby mode”, because it is not intended for extended storage and the RO-device is fluidically connected to the outside.

Claims

02899-25 HeFresenius Medical Care GmbHBad Homburg, Germany&Fresenius Medical Care North AmericaWaltham, MA, USAPortable RO-device configured for isolated stand-byClaims1. Portable Reverse Osmosis- device, comprising a water supply section, a water tank, a reverse osmosis membrane module, a permeate collection line, a retentate line and a control unit, wherein the Reverse Osmosis- device is configured to be operable in an isolated standby mode in that the Reverse Osmosis- device is flu idical ly separated from the outside.

2. Portable Reverse Osmosis- device according to claim 1 , wherein the control unit is configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, a first heat disinfection mode and a second heat disinfection mode, wherein the first heat disinfection mode takes a longer time than the second heat disinfection mode, preferably between 4 to 6 times longer, in particular 5 times longer.

3. Portable Reverse Osmosis- device according to claim 2, wherein the control unit is configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, as the first heat disinfection mode aheat module disinfection in that more components or sections of the Reverse- Osmosis device are disinfected by heat than in the second heat disinfection mode.

4. Portable Reverse Osmosis- device according to claim 3, wherein the first heat disinfection mode runs for 1 to 4 hours.

5. Portable Reverse Osmosis- device according to claim 3 or 4, wherein the control unit is configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, as a second heat disinfection mode a ring heat disinfection in that only a dialysis water section of the reverseosmosis device, preferably comprising a ring line for connecting the reverse osmosis device to a permeate consumer, optionally at least one valve, optionally at least one pump and further optionally the permeate side of the reverse osmosis membrane module, is disinfected.

6. Portable Reverse Osmosis- device according to claim 5, wherein the second heat disinfection mode runs for 5 to 20 minutes.

7. Portable Reverse Osmosis- device according to one of claims 2 to 6, wherein the control unit is configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, at first at least once the first heat disinfection mode followed by repeated performances of the second heat disinfection mode until the isolated standby mode is ended, preferably a maximum of 30 days after the isolated standby mode has been entered by the Reverse-Osmosis device.

8. Portable Reverse Osmosis- device according to claim 7, wherein the control unit is configured to perform the second heat disinfection mode at regular intervals, preferably once daily, until the isolated standby mode is ended.

9. Portable Reverse Osmosis- device according to one of the preceding claims, wherein the control unit is configured to effect, in a state in that the Reverse Osmosis- device is operated in the isolated standby mode, a circulation step in that water is circulated within the Reverse Osmosis- device, wherein the circulation step is preferably performed at regular intervals, in particular every 3-5 hours, preferably every 4 hours.

10. Portable Reverse Osmosis- device according to one of the preceding claims, wherein the control unit is further configured to effect an initial rinsing step prior to entering the reverse osmosis device into the isolated standby mode, wherein during the initial rinsing step the Reverse Osmosis-device is preferably rinsed with water at a flow rate of between 0.8 L / min to 1.3 L / min and a volume of between 5 L and 75 L.

11. Portable Reverse Osmosis- device according to claim 10, wherein, after the instruction to enter the reverse-osmosis device into the isolated standby mode has been received by the control unit, the control unit is configured to perform only the initial rinsing step prior to the fluidical separation of the Reverse-Osmosis device from the outside without the need for a decalcification step and I or heat disinfection step prior to the fluidical separation of the Reverse-Osmosis device from the outside.

12. Portable Reverse Osmosis- device according to one of the preceding claims, wherein, after the instruction to enter the Reverse-Osmosis device into the isolated standby mode has been received by the control unit, the control unit is configured to effect a control such that the Reverse Osmosis- device is in the isolated standby mode 15 minutes to 1 hour after the receipt of the instruction to enter the Reverse-Osmosis device into the isolated standby mode by the control unit.

13. Portable Reverse Osmosis- device according to one of the preceding claims, wherein the control unit, after having received an instruction to exit the isolated standby mode, is configured to instruct a user to fluidically connect the Reverse Osmosis- device to a water feed and drain line.

14. Portable Reverse-Osmosis device according claim 13, wherein the control unit, after having received an instruction to exit the isolated standby mode is configured to effect a device test to check the function of the Reverse Osmosis- device, and preferably, after the device test, effect a rinsing step in that preferably the entire Reverse Osmosis- device is rinsed with a volume of water between 45 L and 55 L at a flow rate of between 0.8 L / min to 1.3 L / min.

15. Portable Reverse Osmosis- device according to one of the preceding claims, wherein the Reverse Osmosis- device is portable and I or movable by a single person and preferably is equipped with wheels.

16. Portable Reverse Osmosis- device according to one of the preceding claims, wherein the Reverse Osmosis- device is configured to provide medical grade water, preferably dialysis water.

17. System comprising at least one portable Reverse Osmosis- device according to one of the preceding claims and at least one permeate consumer, preferably a dialysis device, fluidically coupled to the Reverse Osmosis- device.

18. System according to claim 17, wherein at least two dialysis devices are fluidically coupled to the at least one portable Reverse Osmosis- device.

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