Filter-supporting unit and apparatus with the filter-supporting

The modular filtration apparatus with integrated flowpaths addresses the issues of high hold-up volumes and complex assembly in conventional systems by enabling direct assembly and accurate pressure measurement, enhancing the evaluation of filtration member performance.

WO2026139263A1PCT designated stage Publication Date: 2026-07-02CYTIVA US LLC +1

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
CYTIVA US LLC
Filing Date
2025-12-15
Publication Date
2026-07-02

AI Technical Summary

Technical Problem

Conventional filtration test apparatuses suffer from high hold-up volumes due to tubing connections between filtration member clamps, leading to inaccurate pressure data, complex assembly, and limited ability to measure pressure at different locations along the flowpath.

Method used

A modular apparatus comprising an upstream unit, intermediate units, and a downstream unit, which support filtration members with integrated flowpaths, eliminating the need for auxiliary tubing and allowing direct assembly of filtration members in series.

Benefits of technology

The apparatus provides accurate pressure measurements and simplifies assembly, reducing hold-up volumes and enabling efficient evaluation of filtration member performance, thus accurately representing manufacturing-scale conditions.

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  • Figure EP2025087156_02072026_PF_FP_ABST
    Figure EP2025087156_02072026_PF_FP_ABST
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Abstract

The present disclosure relates to a filter supporting unit (110, 120a, 120b, 130). The unit (110, 120a, 120b, 130) may comprise a first clamping portion (125a) configured for supporting a first filtration member (151) and a second clamping portion (124a) configured for supporting a second filtration member (152). The unit (110, 120a, 120b, 130) may further comprise a flowpath extending through the unit (110, 120a, 120b, 130). The flowpath may be configured such that fluid can flow from the first filtration member (151) to the second filtration member (152).
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