Blood coagulation composition comprising calcium lactate as active ingredient and use thereof

A calcium lactate-based composition addresses the limitations of existing hemostatic products by promoting rapid and stable clot formation and preventing adhesions, effectively controlling severe bleeding and surgical adhesions.

WO2026142203A1 Publication Date: 2026-07-02METIMEDI PHARMA CO LTD
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Patent Information

Application Number
PCT/KR2025/022391
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-26
Filing Date
2025-12-19
Publication Date
2026-07-02

AI Technical Summary

Technical Problem

Current hemostatic products fail to effectively control severe bleeding, particularly in compressive hemorrhage, and do not prevent postoperative adhesions, with limitations including inadequate adhesion to wounds, handling issues, and inefficacy under high-pressure bleeding.

Method used

A blood coagulation composition comprising calcium lactate as an active ingredient, dispersed on an absorbent carrier, which promotes rapid hemostasis and prevents adhesions by activating coagulation factors and stabilizing blood clots.

Benefits of technology

The calcium lactate composition effectively stops bleeding and prevents postoperative adhesions by enhancing clot formation and stability, demonstrating superior thrombus formation and transglutaminase activity compared to calcium chloride, and reducing adhesion formation.

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Abstract

The present invention relates to a blood coagulation composition comprising calcium lactate as an active ingredient, a method for treating a wound or reducing bleeding at a bleeding site, the method comprising a step of administering the composition of the present invention to the wound or the bleeding site, an anti-adhesion composition comprising calcium lactate as an active ingredient, and a method for preventing adhesion during surgery and after surgery, the method comprising a step of administering the composition of the present invention during surgery and after surgery.
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