Stable pharmaceutical choline succinate substance
By adding 0.01-2.00 wt.% of O-(2-hydroxyethoxyethyl)trimethylammonium to choline succinate, the stability of the pharmaceutical substance is enhanced, maintaining the active substance's content and properties during storage, addressing the stability issues of choline succinate.
WO2026142461A1PCT designated stage Publication Date: 2026-07-02OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU ELLARA
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTYU ELLARA
- Filing Date
- 2025-10-14
- Publication Date
- 2026-07-02
AI Technical Summary
Technical Problem
Existing pharmaceutical substances of choline succinate lack stability during long-term storage, leading to significant changes in chemical, physical, and pharmacological properties, which compromises the efficacy of medicinal products based on them.
Method used
Incorporating 0.01-2.00 wt.% of the compound O-(2-hydroxyethoxyethyl)trimethylammonium into choline succinate enhances its stability by using nuclear magnetic resonance spectroscopy for quantitative detection.
Benefits of technology
The incorporation of the compound (I) maintains the stability of choline succinate within the specified range, ensuring minimal changes in active substance content during storage, thereby preserving the pharmaceutical product's integrity.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure RU2025050353_02072026_PF_FP_ABST
Abstract
The invention relates to the field of pharmaceutics, and more particularly to a pharmaceutical choline succinate substance for use in the preparation of medicaments. Proposed is a pharmaceutical choline succinate substance containing 0.01-2.00 wt.% of a compound of formula (I). The obtained substance has elevated stability.
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