Samples Introduction/Extraction TRIZ Cases

Desalting, acoustic ejection, and ion mobility selection cut LC/MS run time and ion suppression for small-volume urine analysis.

A slotted ion funnel separates ion flow from gas exhaust to cut turbulence and fragmentation while enabling real-time calibrant introduction.

A cooled gas-heater fixture blocks heat conduction to the sample probe, preventing boiling and stabilizing ion analyzer signals.

Initial peak-width scans automatically set dwell times in differential mobility mass spectrometry, cutting cycle time while preserving multi-analyte precision.

Low-power laser feedback and radiant heating track surface protein denaturation in real time for uniform, reproducible MALDI-MS sample prep.

Mass spectrometry detects mycobacterial lipid peak sets in transplant candidate samples, enabling faster screening than culture-based methods.

Profiled ion funnel entrances and exits limit gas conductance at higher pressure while preserving ion trajectories and fragmentation efficiency.

A PTFE membrane transfer line swaps atmospheric gas for sweep gas, keeping ICP plasma stable during laser ablation sample changeover.

Low-pressure ion guidance aligns analyte flow with reagent ions to boost sensitivity, cut memory effects, and speed sequential sample screening.

A non-sealed inert-gas chamber enables non-contact laser ablation ICP-MS, limiting contamination and aerosol diffusion for fast local trace analysis.

Neutral droplet spray generates analyte ions at ambient pressure without sample preparation, vacuum, high voltage, or close instrument placement.

Hydrophobic boundaries confine inspection liquid on semiconductor surfaces, enabling faster collection and cleaner metal contamination analysis.

Focused tonebursts raise and sustain a liquid mound, then eject subwavelength droplets in sequence to improve sample throughput and reduce waste.

Segmented reaction and separation with rinsing flows keeps IRMS interface channels clear during extended analysis of particle-forming samples.

A hermetically sealed chamber with inert gas flow and climate control stabilizes vapor analysis and reduces contamination between samples.

Atmospheric bubbles segment transport liquid in an open port interface, improving sample isolation, peak resolution, and mass spectrometry throughput.

Sequential ion fraction transfer preserves narrow isolation quality across a wider precursor m/z range while improving duty cycle in mass spectrometry.

An angled gas injection creates a counter-flow vortex that rejects large droplets, improving ICP aerosol transport and plasma stability.

A rough-top, smooth-bottom porous support retains sample components while draining excess liquid to improve DESI mass spectrometry sensitivity.

Pressure-driven surface impact breaks aerosol molecular clusters into gaseous ions, improving sensitivity while reducing interface contamination.