Dietary butyrate

Triglycerides with long chain fatty acids address the sensory limitations of butyrate sources like butyric acid and tributyrin, providing effective intestinal delivery and improved taste/odor for nutritional compositions.

AU2020398693B2Pending Publication Date: 2026-07-09SOCIETE DES PRODUITS NESTLE SA
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Patent Information

Application Number
AU2020398693
Authority / Receiving Office
AU · AU
Patent Type
Applications
Current Assignee / Owner
Priority Date
2019-12-05
Filing Date
2020-12-04
Publication Date
2026-07-09
Estimated Expiration
2040-12-04

AI Technical Summary

Technical Problem

Existing dietary sources of butyrate, such as butyric acid and tributyrin, are limited by rapid gastric lipolysis and possess unpleasant sensory qualities like bitterness and vomit-like aroma, making oral administration difficult, especially in pediatric populations.

Method used

Development of triglycerides with long chain fatty acids (16-20 carbons) as the main butyrate moiety, providing a dietary source of butyrate with improved organoleptic properties, such as reduced bitterness and improved taste and odor, suitable for nutritional compositions including dietary supplements and medical foods.

Benefits of technology

The triglycerides effectively deliver butyrate to the intestinal compartment with enhanced gastrointestinal health benefits while overcoming sensory drawbacks, offering improved taste and odor profiles.

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Abstract

A nutritional composition for providing a source of butyrate or butyric acid comprising a compound having the formula (1) wherein R6 is a long chain fatty acid having between 16 and 20 carbons.
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