A coenzyme Q10 oil preparation and its preparation method and application

By grinding coenzyme Q10 crystals to a specific particle size and combining them with mixed oils and a two-phase emulsifier, the problems of coenzyme Q10's easy precipitation and poor solubility in oils are solved, and a high-content, stable molecular form of coenzyme Q10 oil is achieved, which improves its bioavailability and antioxidant effect and expands its scope of application.

CN116036060BActive Publication Date: 2025-09-26XIAMEN KINGDOMWAY BIOTECH CO LTD +1
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Patent Information

Application Number
CN202310111297.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-02-14
Publication Date
2025-09-26
Estimated Expiration
2043-02-14

AI Technical Summary

Technical Problem

Coenzyme Q10 in existing coenzyme Q10 products tends to precipitate in a crystalline state, making it difficult to use at high concentrations, resulting in low bioavailability and poor solubility in oils, making it unable to effectively exert its antioxidant and anti-aging effects.

Method used

By grinding coenzyme Q10 crystals to a D50 of 50-120nm and dissolving them under negative pressure under the combined action of mixed oils and a two-phase emulsifier, a stable molecular form is formed. The solubility-promoting ability of the mixed oils and the interaction between the components are utilized to maintain the stability of coenzyme Q10 in the oil.

Benefits of technology

The stable existence of coenzyme Q10 at high content is achieved, the bioavailability is improved, the antioxidant and anti-aging effects are enhanced, and crystallization is avoided. It is suitable for use in food, cosmetics, health products or medicines.

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Abstract

The present invention belongs to the field of coenzyme Q10 technology and relates to a coenzyme Q10 oil, a preparation method thereof, and an application thereof. The coenzyme Q10 oil contains the following components in percentage by mass: 20-40% coenzyme Q10, 45-65% mixed oil, 10-15% biphasic emulsifier, and 0-3% optional antioxidant; the coenzyme Q10 in the coenzyme Q10 oil exists in a molecular form above 0°C; the mixed oil contains both saturated fatty acids (esters) and unsaturated fatty acids (esters); the biphasic emulsifier contains both a hydrophilic emulsifier and a lipophilic emulsifier. The coenzyme Q10 in the coenzyme Q10 oil provided by the present invention can still stably exist in a molecular form at high content, and has high bioavailability.
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