Non-invasive regulation of thoracic sympathetic nerves for the treatment of primary hyperhidrosis using an artificial intelligence wearable device

Abstract

The present invention discloses an artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary hyperhidrosis of the hands, comprising: a main controller, a pulse generator, a first stimulation electrode, a second stimulation electrode, and a third stimulation electrode; the pulse generator is used to generate specific pulse signals for the first, second, and third stimulation electrodes; the first stimulation electrode is set at a position corresponding to the surface of the radial nerve at the wrist, the second stimulation electrode is set at a position corresponding to the surface of the median nerve at the wrist, and the third stimulation electrode is set at a position corresponding to the surface of the ulnar nerve at the wrist, and primary hyperhidrosis of the hands is treated by pulsed electrical stimulation of the radial nerve, median nerve, and ulnar nerve. The device is non-invasive, does not damage human nerves and normal tissues, does not have serious complications such as postoperative compensatory hyperhidrosis and desympathization, does not have the risk of general anesthesia accidents, and provides continuous treatment with accompanying intelligent recognition. It is convenient, effective, and safe, and can maintain therapeutic effects for a long time.

Description

Technical Field

[0001] The present invention relates to the technical field of wearable medical devices, and in particular to an artificial intelligence wearable device for non-invasively regulating thoracic sympathetic nerves to treat primary palmar hyperhidrosis. Background Art

[0002] Primary palmar hyperhidrosis is a functional, localized hyperhidrosis with an unknown pathogenesis. It involves abnormally elevated excitability of the thoracic sympathetic nerves innervating the sweat glands in the hands, leading to abnormal sweat gland secretion in the hands, independent of external temperature. Symptoms include increased sweating in the palms caused by tension, excitement, stress, or in hot weather. Even in cold weather, sweaty hands persist and can lead to more serious consequences, such as increased frostbite on the fingers.

[0003] Currently, non-surgical treatment for primary palmar hyperhidrosis primarily relies on medication, which has short-lived and unsustainable effects. Once the medication's effects wear off, palmar hyperhidrosis symptoms gradually return, resulting in temporary relief. Although repeated treatments are effective, long-term oral or injectable medications can lead to numerous side effects, including drug accumulation. Injectable medications are technically challenging, increase adverse drug reactions, and are harmful to the body. Surgical treatment primarily involves thoracic sympathectomy and perforator resection. Thoracic sympathectomy, performed under a thoracoscopic approach, is an irreversible surgical nerve destruction procedure. It requires general anesthesia and double-lumen endotracheal intubation, placing high demands on anesthesia techniques and perioperative monitoring. Although this minimally invasive procedure involves accessing the thoracic cavity for resection, it carries the risk of common complications of thoracic surgery, such as traumatic pneumothorax, persistent air leak, bleeding, and effusion. Following thoracic sympathectomy, palmar hyperhidrosis symptoms can be alleviated to some extent within two years. However, beyond two years, palmar hyperhidrosis can progressively worsen with time after surgery. Many patients will immediately experience side effects such as compensatory sweating in other parts of the body, excessive dryness of the palms, and desympathization after surgery. Compensatory sweating, in particular, makes the quality of life worse after surgery than before the surgery. Thoracic sympathectomy causes permanent damage to the anatomical structure and physiological function of the sympathetic nerves, which cannot be repaired. Many patients who have undergone surgery often regret the surgery. The essence of thoracic sympathectomy is to destroy the thoracic sympathetic nerves. The safety and effectiveness of the surgery are currently controversial in the international medical community. The health administrative departments of some countries and regions have explicitly banned this surgery. However, to date, there is no medical solution to the problem of compensatory sweating after hyperhidrosis of the hands, which has a great impact on the quality of life of patients.

[0004] There is an urgent need for an effective, convenient, and non-invasive treatment method to reduce patients' pain and avoid surgical risks. Summary of the Invention

[0005] In view of this, the object of the present invention is to provide an effective, convenient, non-invasive treatment method and equipment for primary hyperhidrosis of the hands.

[0006] To achieve the objectives of the present invention, without being limited by any theory, the inventors of the present invention unexpectedly discovered that by applying pulsed electrical stimulation to the surface of specific nerves in the wrist, the neural electrical signals are transmitted through the nerve trunk and spinal cord to the thoracic sympathetic nerves, stimulating the release of corresponding neurotransmitters in the brain and spinal cord, thereby inhibiting the excitation of the thoracic sympathetic nerves and controlling excessive sweating of the hands. This achieves a convenient, effective, low-cost, non-invasive, accompanied by intelligent identification and continuous treatment to treat primary hyperhidrosis of the hands through neuromodulation. As disclosed herein, the stimulation is therapeutic, that is, after the onset of symptoms.

[0007] In one embodiment, the present invention provides an artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis, which is worn on the wrist of a user. The artificial intelligence wearable device includes:

[0008] A main controller, a pulse generator, a first stimulation electrode, a second stimulation electrode, and a third stimulation electrode;

[0009] The pulse generator is used to generate specific pulse signals for the first, second and third stimulation electrodes under the control of the main controller;

[0010] The first stimulation electrode is provided at a position corresponding to the surface of the radial nerve of the wrist, the first stimulation electrode is connected to the pulse generator, and the first stimulation electrode transmits the pulse signal to the surface of the radial nerve;

[0011] The second stimulation electrode is arranged at a position corresponding to the surface of the median nerve at the wrist, and the second stimulation electrode is connected to the pulse generator, and the second stimulation electrode transmits the pulse signal to the surface of the median nerve;

[0012] The third stimulation electrode is provided at a position corresponding to the surface of the ulnar nerve of the wrist, the third stimulation electrode is connected to the pulse generator, and the third stimulation electrode transmits the pulse signal to the surface of the ulnar nerve;

[0013] Primary palmar hyperhidrosis is treated by pulsed electrical stimulation of the radial, median, and ulnar nerves.

[0014] In a specific embodiment, the body surface site of the radial nerve includes Lieque point, the body surface site of the median nerve includes Daling point, and the body surface site of the ulnar nerve includes Shenmen point.

[0015] In a specific embodiment, the pulse signal is an amplitude modulated wave signal.

[0016] In a specific embodiment, the pulse signal is a positive and negative symmetrical square wave.

[0017] In a specific embodiment, each pulse of the pulse signal is a positive and negative symmetrical square wave, or adjacent pulses in the pulse signal are positive and negative symmetrical.

[0018] In a specific embodiment, the pulse signal has a pulse frequency of 10-200 Hz, an amplitude of 0.1-5.3 s, and a current intensity of 0.1-3.9 mA.

[0019] In a specific embodiment, the pulse generator generates identical pulse signals for the first, second, and third stimulation electrodes.

[0020] In a specific embodiment, the artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis further includes an environmental information sensor for collecting environmental information and motion information, and / or a physiological parameter collector;

[0021] In a specific embodiment, the main controller triggers the pulse generator to generate or stop generating the pulse signal according to the environmental information, motion information and / or physiological parameters.

[0022] In a specific embodiment, the environmental information sensor includes a temperature sensor, a humidity sensor, an accelerometer or a gyroscope, and the physiological parameter collector includes a heart rate sensor, a blood pressure collector and / or a body temperature measurer.

[0023] In a specific embodiment, the artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis also includes a wireless communication module to receive remote medical control instructions, and the main controller triggers the pulse generator to generate the pulse signal according to the remote medical control instructions.

[0024] In a specific embodiment, the artificial intelligence wearable device also includes a wrist connecting strap and a main body, the first stimulation electrode, the second stimulation electrode and the third stimulation electrode are arranged on the wrist connecting strap, the transmission circuit is buried in the wrist connecting strap, the main controller and the pulse generator are arranged in the main body, and the transmission circuit connects the first stimulation electrode, the second stimulation electrode and the third stimulation electrode to the pulse generator.

[0025] In one embodiment, a method for treating primary hyperhidrosis of the hands is provided, comprising: continuously electrically stimulating three anatomical sites on the wrist: the median nerve, the ulnar nerve, and the radial nerve. In one embodiment, stimulating electrodes are positioned at the three anatomical sites on the wrist: the median nerve, the ulnar nerve, and the radial nerve, and continuously electrically stimulated.

[0026] In one embodiment, a method for treating primary hyperhidrosis of the hands is provided, comprising: continuously stimulating three Traditional Chinese Medicine acupuncture points on the wrist: Shenmen, Daling, and Lieque. In one embodiment, stimulating electrodes are positioned at the three Traditional Chinese Medicine acupuncture points on the wrist: Shenmen, Daling, and Lieque, and continuously stimulating with electricity.

[0027] In one embodiment, the stimulation duration is 15-60 minutes, for example, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60 minutes.

[0028] According to another aspect of the present invention, the present invention provides the use of the median nerve, ulnar nerve, and radial nerve in treating primary palmar hyperhidrosis.

[0029] In a specific embodiment, the application includes continuous electrical stimulation of three anatomical sites on the body surface: the median nerve, the ulnar nerve, and the radial nerve.

[0030] According to another aspect of the present invention, the present invention provides the use of Shenmen, Daling and Lieque points in treating primary palmar hyperhidrosis.

[0031] In a specific embodiment, the application includes continuous electrical stimulation of three acupuncture points in traditional Chinese medicine: Shenmen, Daling, and Lieque.

[0032] According to the solution of the present invention, by wearing an electronic device on the body, there is no need for surgical treatment, no need to cut off or damage the human thoracic sympathetic nerves, no risks of adverse drug reactions, no general anesthesia accidents, etc., and the serious complications of hyperhidrosis of the hands after surgery, such as compensatory hyperhidrosis and desympathization, which have plagued clinical practice for many years, are solved, and the safety of treatment is significantly improved.

[0033] The severity of symptoms of primary palmar hyperhidrosis varies throughout the day. The solution of the present invention can be divided into different time periods and the various parameters and stimulation times of the control pulses can be adaptively adjusted to achieve moderate regulation of the thoracic sympathetic nerves, maintain the normal warmth and moistness of the palm skin, and avoid the side effect of excessive dryness of the palms.

[0034] The present invention performs neuroregulation in a safe and non-invasive manner, with accompanying intelligent identification and continuous treatment, without damaging human nerves and normal tissues, and without postoperative complications such as postoperative compensatory hyperhidrosis and desympathetic degeneration, and in a convenient, effective and low-cost manner. It has a good therapeutic effect on the treatment of primary palmar hyperhidrosis, can maintain the therapeutic effect for a long time, and reduce treatment costs.

[0035] The solution of the present invention can achieve continuous electrical stimulation and regulation of the cutaneous nerves, can continuously maintain the treatment effect, and can automatically judge the human body state, automatically shut down, and end the treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention but do not constitute a limitation of the present invention. In the accompanying drawings:

[0037] Figure 1 A schematic diagram showing the structure of the artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis according to the present invention;

[0038] Figure 2 A schematic diagram showing the nerve distribution of the human hand;

[0039] Figure 3 A schematic diagram showing the surface locations of the radial nerve, median nerve, and ulnar nerve;

[0040] Figure 4 A schematic diagram showing the functional framework of the artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis of the present invention;

[0041] Figure 5 、 6 A schematic diagram of the pulse signal waveform is shown. DETAILED DESCRIPTION

[0042] The following describes the implementation process of the technical solution of the present invention in conjunction with specific embodiments, which are not intended to limit the present invention.

[0043] The present invention provides an artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis. The device can be specifically configured as a watch, bracelet, wristband or wristband. However, it should be understood that other devices worn on the wrist are also within the scope of the present invention. Alternatively, the present invention can be integrated as a module into an existing wrist wearable device.

[0044] Without being limited to any theory, according to the present invention, when the artificial intelligence wearable device is worn on the wrist, a stimulation electrode is provided at the component corresponding to the palm side, and pulse electrical stimulation is performed on the surface of specific nerves in the wrist, so that the neural electrical signals are transmitted to the thoracic sympathetic nerves through the nerve trunk and spinal cord, stimulating the release of corresponding neurotransmitters in the brain and spinal cord, thereby inhibiting the excitement of the thoracic sympathetic nerves and controlling excessive secretion of hand sweat.

[0045] The present invention performs neuromodulation in a non-invasive, accompanying intelligent identification continuous treatment, convenient, effective and low-cost manner, has excellent efficacy in treating primary palmar hyperhidrosis and reduces treatment costs.

[0046] like Figure 1 FIG2 is a schematic diagram showing the structure of an artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis according to the present invention, taking a smartwatch as an example. Other common functional modules of the smartwatch are not shown in the figure.

[0047] like Figure 2 As shown, a schematic diagram of the nerve distribution of the human hand is shown.

[0048] like Figure 3 As shown, a schematic diagram of the surface locations of the radial nerve, median nerve, and ulnar nerve is shown.

[0049] like Figure 4 , which shows a functional framework diagram of the artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary palmar hyperhidrosis of the present invention.

[0050] The artificial intelligence wearable device 100 comprises a main body, which can be a watch face, and a wrist strap, which is provided with a first stimulation electrode 10, a second stimulation electrode 20, and a third stimulation electrode 30. Inside the watch face are a main controller 40 and a pulse generator 50. The main controller 40 is connected to the first stimulation electrode 10, the second stimulation electrode 20, and the third stimulation electrode 30 via a transmission circuit embedded in the wrist strap.

[0051] The human arm has the radial nerve, median nerve, and ulnar nerve, all of which are responsible for the skin's sensory function and autonomic nervous function.

[0052] The first stimulation electrode 10 is located at the surface of the radial nerve at the wrist, the second stimulation electrode 20 is located at the surface of the median nerve at the wrist, and the third stimulation electrode 30 is located at the surface of the ulnar nerve at the wrist.

[0053] The surface part of the radial nerve includes the Lieque point, the surface part of the median nerve includes the Daling point, and the surface part of the ulnar nerve includes the Shenmen point. The first stimulating electrode 10 only needs to be attached to the surface part of the corresponding radial nerve. The second and third stimulating electrodes are similar. The pulse signals emitted by the electrodes can stimulate the corresponding nerves. Preferably, the first stimulating electrode 10 is attached to the acupoint location of the Lieque point. Preferably, the second stimulating electrode 20 is attached to the acupoint location of the Daling point. Preferably, the third stimulating electrode 30 is attached to the acupoint location of the Shenmen point.

[0054] The main controller 40 is connected to the pulse generator 50 , and the pulse generator 50 is connected to the first stimulation electrode 10 , the second stimulation electrode 20 , and the third stimulation electrode 30 respectively.

[0055] The pulse generator 50 is used to generate a specific pulse signal under the control of the main controller 40, and the specific pulse signal is transmitted to the first, second, and third stimulation electrodes.

[0056] The first stimulating electrode transmits the pulse signal to the surface of the radial nerve. The second stimulating electrode transmits the pulse signal to the surface of the median nerve. The third stimulating electrode transmits the pulse signal to the surface of the ulnar nerve, and the neural electrical signal is transmitted to the thoracic sympathetic nerve through the nerve trunk and spinal cord, stimulating the release of corresponding neurotransmitters in the brain and spinal cord, thereby inhibiting the excitement of the thoracic sympathetic nerve. The thoracic sympathetic nerve transmits the inhibitory signal to the sweat glands in the palms, thereby inhibiting the secretion of the sweat glands in the palms that it controls, and causing the symptoms of hyperhidrosis to disappear. The pulse signal uses an amplitude modulated wave signal. Based on the effective energy of hyperhidrosis and human safety, the pulse frequency of the pulse signal can be in the range of 10-200Hz, the amplitude of the pulse signal can be in the range of 0.1-5.3s, and the current intensity of the pulse signal can be in the range of 0.1-3.9mA. Usually, the stimulation time of the pulse signal needs to last for 15-30 minutes to produce a therapeutic effect.

[0057] The pulse signal can be a positive and negative symmetrical square wave. Specifically, each pulse of the pulse signal is a positive and negative symmetrical square wave (such as Figure 5 As shown), or, the adjacent pulses in the pulse signal are positive and negative symmetrical (as shown Figure 6 shown).

[0058] The pulse generator 50 generates identical pulse signals for the first, second, and third stimulation electrodes. Since the three stimulation electrodes receive identical signals, the stimulation intensity of each electrode is identical, eliminating asymmetric stimulation intensity and electrode polarization, thereby preventing electric shock accidents.

[0059] for Figure 6 In the pulse signal shown, since each pulse has a positive and negative symmetrical waveform, the pulse energy is doubled and the stimulation effect per unit time is enhanced.

[0060] like Figure 4 As shown, the artificial intelligence wearable device 100 also includes an environmental information sensor 70 for collecting environmental information and motion information, and / or a physiological parameter collector 60. The environmental information sensor includes a temperature sensor, a humidity sensor, an accelerometer and / or a gyroscope, and the physiological parameter collector includes a heart rate sensor, a blood pressure collector and / or a body temperature meter.

[0061] The artificial intelligence wearable device 100 also includes a storage unit 90 for storing a pulse signal triggering scheme. The main controller 40 triggers the pulse generator to generate or stop generating the pulse signal based on the environmental information, motion information, and / or physiological parameters. The main controller 40 can also trigger the pulse generator to generate or stop generating the pulse signal based on a preset scheme. The preset scheme can be a timed trigger / shutdown.

[0062] The artificial intelligence wearable device 100 can collect physiological information of the human body through the physiological parameter collector 60, and select a treatment plan for execution based on the physiological information. For example, it can judge whether the human body has woken up from sleep or entered sleep through heart rate, blood pressure, and body temperature. The transition of the sleep state is an important node of hyperhidrosis. The storage unit 90 stores the pulse triggering scheme corresponding to the transition of the sleep state based on the heart rate. For example, when the main controller judges that the human body has woken up according to the data collected by the physiological parameter collector, the pulse generator 50 is triggered to generate a pulse signal according to the pulse triggering scheme. The three stimulation electrodes continue to send pulse signals for 15 minutes and then automatically stop. After an interval of 15 minutes, the pulse signals can be sent again for 15 minutes and then stop. When the main controller judges that the human body has entered sleep according to the data collected by the physiological parameter collector, the pulse generator 50 is controlled to stop generating pulse signals. Other triggering schemes are also within the scope of the disclosure of the present invention.

[0063] The artificial intelligence wearable device 100 can collect environmental information or motion information through the current time and the environmental information sensor 70. For example, it can judge the human body's environment and movement mode through a temperature sensor, humidity sensor, accelerometer or gyroscope, and then judge the degree of sweating. The main controller adaptively and dynamically adjusts the parameters of the pulse signal according to the pulse triggering scheme to control the stimulation time.

[0064] In one embodiment, when the heart rate reaches 81 beats / min and the blood pressure reaches about 130 / 70 mm, the stimulation time is adjusted to more than 30 minutes. Figure 4 As shown, the artificial intelligence wearable device 100 also includes a wireless communication module 80, which can be a 5G module to connect to the telemedicine platform, and transmit the information collected by the physiological parameter collector 60 and the environmental information sensor 70 / the image information taken by the artificial intelligence wearable device 100 / the text information sent by the artificial intelligence wearable device 100 to the telemedicine platform at any time. The server of the telemedicine platform or the remotely connected medical service personnel makes telemedicine control instructions according to the human body condition, and the artificial intelligence wearable device 100 receives the telemedicine control instructions through the wireless communication module, and the main controller triggers the pulse generator 50 to generate the pulse signal according to the telemedicine control instruction.

[0065] Some application cases of the present invention are described below.

[0066] Patient 1, Zhao, a 23-year-old male, is a Chinese national boxing team athlete. He was clinically diagnosed with severe primary hyperhidrosis of the palms, characterized by dripping sweat in his hands. Originally an inpatient in the Department of Thoracic Surgery, he declined thoracotomy. He subsequently volunteered for a trial treatment using the present invention in the Neurobiology Department's research laboratory at Capital Medical University. After 30 minutes of continuous use of the device, his hand sweating disappeared. After discontinuing the device, his hands remained sweat-free for 60 minutes, and subsequent follow-up revealed no significant systemic findings.

[0067] Patient 2, Zhang, a 29-year-old male, was diagnosed with moderate primary hyperhidrosis of the palms, characterized by scattered sweating on both hands. After using the device for 5 minutes, the sweating began to subside. After 15 minutes, the sweating disappeared. After stopping the device, the hands remained sweat-free for 60 minutes.

[0068] In clinical practice, maintaining no sweat for 60 minutes after the termination of nerve stimulation can be judged as clinically effective.

[0069] To date, the inventors have conducted 189 clinical treatments at Capital Medical University for patients diagnosed with moderate and severe primary hyperhidrosis using the technical solutions of this invention. All cases achieved sustained sweat-free status for 60 minutes after treatment. This invention demonstrates excellent therapeutic efficacy for all types of primary hyperhidrosis and demonstrates clinical effectiveness.

[0070] The present invention regulates the thoracic sympathetic nerves in a non-invasive, accompanying intelligent treatment, convenient and effective manner. It does not require surgical treatment, does not require cutting off or damaging the human thoracic sympathetic nerves, has no adverse drug reactions, and does not have the risk of general anesthesia accidents. It has excellent and safe efficacy in treating primary palmar hyperhidrosis, avoids the occurrence of serious complications such as postoperative compensatory hyperhidrosis and desympathization, and is safe, effective, sustainable, repeatable, and reduces treatment costs. The severity of symptoms of primary palmar hyperhidrosis varies throughout the day. The solution of the present invention can be divided into different time periods, and the various parameters and stimulation times of the control pulses can be adaptively adjusted to achieve intelligent regulation of the thoracic sympathetic nerves, maintain the normal warmth of the palm skin, and avoid the side effect of excessive dryness of the palm. The solution of the present invention can achieve continuous electrical stimulation and regulation of the cutaneous nerves, can be used for long-term treatment, can continuously maintain the treatment effect, and can automatically judge the state of the human body, automatically shut down, and end the treatment.

[0071] The above embodiments are only used to describe the technical solutions of the present invention and are not to be construed as limiting the present invention.

Claims

1. An artificial intelligence wearable device for non-invasively regulating the thoracic sympathetic nerves to treat primary hyperhidrosis of the hands, worn on the user's wrist, characterized by: The AI ​​wearable device includes: A main controller, a pulse generator, a first stimulation electrode, a second stimulation electrode, and a third stimulation electrode; The pulse generator is used to generate a specific pulse signal for the first, second, and third stimulation electrodes under the control of the main controller. The pulse signal is an amplitude modulated wave signal. Based on the effective energy of hand hyperhidrosis and human safety, the pulse frequency of the pulse signal is 10-200 Hz, the current intensity is 0.1-3.9 mA, and the pulse signal lasts for 15-30 minutes. Each pulse of the pulse signal is a positive and negative symmetrical square wave, or adjacent pulses in the pulse signal are positive and negative symmetrical; The first stimulation electrode is provided at a position corresponding to a surface portion of the radial nerve at the wrist. The first stimulation electrode is connected to the pulse generator and transmits the pulse signal to the surface portion of the radial nerve, wherein the surface portion of the radial nerve includes the Lieque acupoint. The second stimulation electrode is provided at a position corresponding to a surface portion of the median nerve of the wrist. The second stimulation electrode is connected to the pulse generator and transmits the pulse signal to the surface portion of the median nerve, wherein the surface portion of the median nerve includes the Daling acupoint. The third stimulation electrode is provided at a position corresponding to the surface of the ulnar nerve of the wrist. The third stimulation electrode is connected to the pulse generator and transmits the pulse signal to the surface of the ulnar nerve, where the surface of the ulnar nerve includes the Shenmen acupoint. The pulse generator generates identical pulse signals for the first, second, and third stimulation electrodes to eliminate asymmetric stimulation intensity and electrode polarization. By pulsing electrical stimulation on the radial nerve, median nerve and ulnar nerve, the nerve electrical signals are transmitted to the thoracic sympathetic nerves through the nerve trunk and spinal cord, inhibiting the excitement of the thoracic sympathetic nerves and treating primary hyperhidrosis of the hands.

2. The artificial intelligence wearable device for non-invasively regulating thoracic sympathetic nerves to treat primary hyperhidrosis of the hands as claimed in claim 1, characterized in that: It also includes an environmental information sensor for collecting environmental information, motion information, and / or a physiological parameter collector; The main controller triggers the pulse generator to generate or stop generating the pulse signal according to the environmental information, motion information and / or physiological parameters.

3. The artificial intelligence wearable device for non-invasively regulating thoracic sympathetic nerves to treat primary hyperhidrosis of the hands as claimed in claim 2, characterized in that: The environmental information sensor includes a temperature sensor, a humidity sensor, an accelerometer or a gyroscope, and the physiological parameter collector includes a heart rate sensor, a blood pressure collector and / or a body temperature measurer.

4. The artificial intelligence wearable device for non-invasively regulating thoracic sympathetic nerves to treat primary hyperhidrosis of the hands as claimed in claim 1, characterized in that: It also includes a wireless communication module to receive remote medical control instructions, and the main controller triggers the pulse generator to generate the pulse signal according to the remote medical control instructions.

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