Multi-effect white Chinese wolfberry fruit toothpaste for preventing gingival atrophy and preparation method of multi-effect white Chinese wolfberry fruit toothpaste

Abstract

The invention relates to the technical field of Chinese wolfberry fruit toothpaste, in particular to multi-effect pure white Chinese wolfberry fruit toothpaste for preventing gingival atrophy and a preparation method of the multi-effect pure white Chinese wolfberry fruit toothpaste. The method comprises the following steps: 1, preparing raw materials; step 2, preparing a Chinese wolfberry fruit extracting solution; step 3, mixing and stirring; step 4, thickening and seasoning; according to the multi-effect pure white fructus lycii toothpaste capable of preventing gingival atrophy and the preparation method thereof, multiple nutritional ingredients in fructus lycii cooperate with effective substances in the pomegranate peel extract, gingival atrophy can be effectively prevented, and lycium barbarum polysaccharide can adjust immunity, resist oxidation and reduce gingival inflammation; the pomegranate rind tannin has the effects of astringing and resisting bacteria, the vitamin K2 regulates calcium metabolism and strengthens gingival toughness, the secondary combination of the pomegranate rind tannin and the vitamin K2 protects gingiva, reduces the inflammation risk, promotes tissue repair and optimizes calcium distribution from multiple aspects, and gingival atrophy caused by factors such as age and bacterial infection can be effectively prevented, so that the risk of gingival atrophy is reduced, and gingival health and tooth stability are maintained.

Description

Technical Field

[0001] The invention relates to the technical field of wolfberry toothpaste, in particular to a wolfberry toothpaste capable of preventing gum atrophy and achieving multi-effect whitening and a preparation method thereof. Background Art

[0002] As people pay more and more attention to oral health, the research and development of toothpaste products is becoming increasingly diversified. Although traditional wolfberry toothpaste has been on the market for some time, it still has many shortcomings.

[0003] Conventional wolfberry toothpastes often simply add wolfberry ingredients, lacking in-depth extraction and precise use of wolfberry's effective ingredients, which makes it difficult to fully exert its efficacy. In terms of preventing gum atrophy, due to the lack of targeted auxiliary ingredients, it cannot effectively deal with a variety of pathogenic factors, such as aging of gum tissue caused by age, inflammatory gum recession caused by bacterial infection, etc., and cannot provide comprehensive and in-depth protection, resulting in frequent gum atrophy problems, increasing the risk of gum atrophy, and reducing the maintenance of gums;

[0004] Moreover, in terms of teeth whitening effect, the effect of wolfberry itself is relatively limited. It is insufficient to remove stubborn dirt and pigments on the tooth surface. Its cleaning and whitening ability is limited. It cannot completely remove all kinds of stubborn stains and pigment deposits on the tooth surface, and cannot make the teeth reach the ideal white state. It is not effective in improving the beauty of teeth, thus reducing the practicality of wolfberry toothpaste.

[0005] In view of this, there is an urgent need for a wolfberry toothpaste that can prevent gum atrophy and whiten teeth in multiple ways, and a preparation method thereof, so as to meet consumers' requirements for toothpaste that can effectively prevent gum atrophy and effectively remove stubborn stains and pigmentation on teeth, so as to improve the deficiencies of the existing technology. Summary of the invention

[0006] The object of the present invention is to provide a wolfberry toothpaste for preventing gum atrophy and whitening the teeth and a preparation method thereof, so as to solve the problems raised in the above-mentioned background technology.

[0007] To achieve the above object, on the one hand, the present invention provides a method for preparing a wolfberry toothpaste for preventing gum atrophy and whitening the teeth, comprising the following steps:

[0008] S1. Raw material preparation: pre-treated wolfberry powder, pomegranate peel extract, abrasive, moisturizer, surfactant, adhesive, flavoring, preservative and deionized water;

[0009] S2, preparation of wolfberry extract: adding wolfberry powder to 6-10 times the mass of 60%-70% ethanol solution, turning on the ultrasonic generator to extract the wolfberry powder, then filtering with a 200-300 mesh stainless steel filter, collecting the filtrate, and then transferring the filtrate to a vacuum concentration device, and concentrating it under reduced pressure to 1 / 5-1 / 3 of the original volume to obtain a concentrated wolfberry extract;

[0010] S3, mixing and stirring: adding the moisturizer and deionized water into the stirring pot, turning on the stirrer for the first stirring, adding the friction agent after stirring evenly, stirring for the second time, then adding the surfactant and the pomegranate peel extract in sequence, stirring for the third time, and then adding the wolfberry extract for the fourth stirring;

[0011] S4, thickening and seasoning: while stirring continuously, add the binder and stir again, then add the flavoring agent and preservative and stir for the final time;

[0012] S5. Aging and filling: The mixed toothpaste is transferred to a stainless steel aging tank with a sealed lid and aged at room temperature. The temperature and relative humidity in the room are controlled by a temperature and humidity sensor to further stabilize and uniformize the ingredients. After aging, the toothpaste is filled into packaging containers using a toothpaste filling machine and sealed for storage.

[0013] As a further improvement of the present technical solution, in S1, the pretreatment of wolfberry powder requires selecting high-quality dried wolfberries, washing them thoroughly with clean water, and then placing them in an oven for drying. The temperature is controlled at 60°C-70°C. During this period, the moisture content is monitored in real time by a moisture meter until the moisture content is lower than 5%. Subsequently, the dried wolfberries are crushed into 80-120 mesh fine powder using a grinder, and the powder is sealed and stored for later use.

[0014] As a further improvement of the present technical solution, in S1, the pomegranate peel extract includes at least vitamin K2, and the purity of the pomegranate peel extract is above 80%, and the vitamin K2 content is precisely 1%-3%.

[0015] As a further improvement of the present technical solution, in S2, the ultrasonic frequency of the ultrasonic generator is 20kHz-40kHz, and the ultrasonic extraction is performed at 50°C-60°C for 30min-60min.

[0016] As a further improvement of the technical solution, in S2, when the vacuum concentration device performs vacuum concentration, it is necessary to control the vacuum degree to 0.06MPa-0.09MPa and the temperature to 40°C-50°C.

[0017] As a further improvement of the present technical solution, in S3, the speed of the agitator for the first stirring is 30r / min-50r / min, and the stirring time is 5min-10min; the speed of the second stirring is 40r / min-60r / min, and the stirring time is 10min-15min; the speed of the third stirring is 30r / min-50r / min, and the stirring time is 6min-10min; the speed of the fourth stirring is 50r / min-70r / min, and the stirring time is 10min-15min.

[0018] As a further improvement of the technical solution, in S4, the stirring speed for adding the adhesive for re-stirring is increased to 50r / min-80r / min, and the stirring time is 10min-15min; the stirring speed for adding the flavoring agent and preservative for the final stirring is reduced to 30r / min-50r / min, and the stirring time is 5min-10min.

[0019] As a further improvement of the technical solution, in S5, the temperature and humidity sensor controls the indoor temperature at 20°C-25°C, the indoor relative humidity at 40%-60%, and the aging time at 24h-48h.

[0020] As a further improvement of the technical solution, in S5, during the aging process of the toothpaste, it is necessary to gently stir it every 6h-8h, and each stirring time is 2min-3min.

[0021] On the other hand, the present invention provides a wolfberry toothpaste for preventing gum atrophy and whitening the teeth, prepared by any one of the preparation methods described above, comprising the following raw materials in percentage by weight:

[0022] Wolfberry powder, the total amount is 5%-9% of the total weight of toothpaste;

[0023] Pomegranate peel extract, the total amount is 2%-6% of the total weight of the toothpaste;

[0024] Abrasives, the total amount is 20%-30% of the total weight of toothpaste;

[0025] Moisturizer, the total amount is 30%-40% of the total weight of toothpaste;

[0026] Surfactants, the total amount is 1%-3% of the total weight of toothpaste;

[0027] Adhesive, the total amount is 0.5%-1.5% of the total weight of toothpaste;

[0028] Flavoring agent, the total amount is 0.5%-1% of the total weight of toothpaste;

[0029] Preservatives, the total amount is 0.1%-0.2% of the total weight of toothpaste;

[0030] Deionized water, balance.

[0031] Compared with the prior art, the present invention has the following beneficial effects:

[0032] 1. In the multi-effect whitening wolfberry toothpaste for preventing gum atrophy and its preparation method, various nutrients in wolfberry cooperate with effective substances in pomegranate peel extract to effectively prevent gum atrophy. Lycium barbarum polysaccharides can regulate immunity and anti-oxidation and reduce gum inflammation; pomegranate peel tannins are astringent and antibacterial, and vitamin K2 regulates calcium metabolism and strengthens gum toughness. Their secondary combination protects gums from multiple aspects, reduces the risk of inflammation, promotes tissue repair, and optimizes calcium distribution. It can effectively prevent gum atrophy caused by age, bacterial infection and other factors, thereby reducing the risk of gum atrophy and maintaining gum health and tooth stability.

[0033] 2. In the multi-effect whitening wolfberry toothpaste for preventing gum atrophy and its preparation method, the natural acidic components of wolfberry and the tannic acidic components of pomegranate peel extract form a synergistic force, which can effectively decompose the dirt and pigments on the surface of teeth, making the teeth white and bright. At the same time, during the cleaning process, other basic ingredients such as abrasives and moisturizers work synergistically to effectively protect tooth enamel and avoid excessive wear while ensuring cleaning power, so that the teeth can always remain healthy while obtaining good cleaning and whitening effects, thereby improving the oral cleaning effect of wolfberry toothpaste. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 This is a flowchart of the preparation method of the multi-effect whitening wolfberry toothpaste for preventing gum atrophy of the present invention;

[0035] Figure 2 The bar graph is a graph of the gum atrophy prevention, tooth whitening, stability, cleansing and ingredient compatibility of the present invention. DETAILED DESCRIPTION

[0036] The following will be combined with the accompanying drawings in the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.

[0037] The embodiment of the present invention provides a wolfberry toothpaste for preventing gum atrophy and whitening the teeth, comprising the following raw materials in percentage by weight:

[0038] Wolfberry powder, the total amount is 5%-9% of the total weight of toothpaste;

[0039] Pomegranate peel extract, the total amount is 2%-6% of the total weight of the toothpaste;

[0040] The abrasive agent, with a total amount of 20%-30% of the total weight of the toothpaste, is made of one of food-grade calcium carbonate and silicon dioxide. Calcium carbonate can provide moderate friction cleaning power and has a relatively low cost, while silicon dioxide has better chemical stability and delicate friction texture;

[0041] Moisturizer, the total amount is 30%-40% of the total weight of the toothpaste, glycerin and sorbitol are mixed in a ratio of 1:1-2:1. Glycerin has good moisturizing and lubricating properties, while sorbitol helps to improve the stability and taste of the toothpaste. The synergistic effect of the two can maintain the moisture content of the toothpaste during storage and use, preventing the toothpaste from drying up and hardening;

[0042] Surfactant, the total amount is 1%-3% of the total weight of the toothpaste, and sodium lauryl sulfate with a purity of more than 90% is selected. Its main function is to produce rich foam, enhance the cleaning effect and dispersibility of the toothpaste, and enable other ingredients to be evenly distributed in the mouth and fully contact with the tooth surface;

[0043] The total amount of the binder is 0.5%-1.5% of the total weight of the toothpaste. The viscosity index of sodium carboxymethyl cellulose is selected to be 800mPa·s-1200mPa·s. It can form a stable colloidal structure in the toothpaste, give the toothpaste a suitable consistency and plasticity, and ensure that the components will not be stratified or precipitated during storage and use;

[0044] Flavoring agent, the total amount is 0.5%-1% of the total weight of the toothpaste, and can be menthol, flavors and other ingredients. Menthol is extracted from nature and the purity is above 95%. The role of flavoring agent is to improve the taste and smell of toothpaste, so that users can have a pleasant experience during brushing and improve the acceptance of the product;

[0045] Preservatives, the total amount is 0.1%-0.2% of the total weight of the toothpaste, and the purity of sodium benzoate must reach more than 99%, which can effectively inhibit the growth and reproduction of microorganisms in the storage process of toothpaste, prevent the product from deteriorating and moldy, and extend the shelf life;

[0046] Deionized water, the balance, use deionized water that has been treated with multi-stage reverse osmosis, and its conductivity should be less than 5μS / cm.

[0047] according to Figure 1 As shown, the embodiment of the present invention also provides a method for preparing the above-mentioned wolfberry toothpaste for preventing gum atrophy and whitening the teeth, comprising the following steps:

[0048] Step 1, raw material preparation: pre-treated wolfberry powder, pomegranate peel extract, abrasive, moisturizer, surfactant, adhesive, flavoring, preservative and deionized water. The pre-treatment of wolfberry powder requires the selection of high-quality wolfberry dried products, such as wolfberry dried products with bright color, full grains, no mildew and impurities, which are fully washed with clean water and placed in an oven for drying. The temperature is controlled at 60°C-70°C. During this period, the moisture content is monitored in real time by a moisture meter until the moisture content is less than 5%. Subsequently, the dried wolfberry is crushed into 80-120 mesh fine powder by a pulverizer, and sealed and stored for standby use. The pomegranate peel extract includes at least vitamin K2, and the purity of the pomegranate peel extract is above 80%, and the vitamin K2 content is accurately 1%-3%, so as to ensure the quality stability and safety of the raw materials;

[0049] Step 2, preparation of wolfberry extract: add wolfberry powder to 6-10 times the mass of 60%-70% ethanol solution (6-10 times the mass refers to the ratio of wolfberry powder to ethanol solution is 1:6-1:10, 60%-70% ethanol solution refers to the mass fraction concentration of ethanol solution), turn on the ultrasonic generator to extract the wolfberry powder, the ultrasonic frequency of the ultrasonic generator is 20kHz-40kHz, and the ultrasonic extraction is carried out at 50℃-60℃ for 30min-60min, during which time, the stirring device is slowly stirred. Stir slowly to make the wolfberry powder fully contact with the ethanol solution to ensure that the effective ingredients are fully dissolved. Then, filter with a 200-300 mesh stainless steel filter to collect the filtrate, and then transfer the filtrate to a vacuum concentration device for vacuum concentration to 1 / 5-1 / 3 of the original volume. When the vacuum concentration device performs vacuum concentration, the vacuum degree needs to be controlled at 0.06MPa-0.09MPa and the temperature at 40℃-50℃ to obtain a concentrated wolfberry extract. When refrigeration is required for standby use, it needs to be stored at 4℃-8℃;

[0050] Step 3, mixing and stirring: add moisturizer and deionized water into the stirring pot, turn on the stirrer for the first stirring, the speed of the first stirring of the stirrer is 30r / min-50r / min, and the stirring time is 5min-10min; after stirring evenly, add the friction agent for the second stirring, the speed of the second stirring is 40r / min-60r / min, and the stirring time is 10min-15min, so that it is fully dispersed; then, add the surfactant and pomegranate peel extract in turn for the third stirring, the speed of the third stirring is 30r / min-50r / min, and the stirring time is 6min-10min; make the two ingredients evenly dispersed in the mixture to ensure that no precipitation or stratification occurs, and then add the wolfberry extract for the fourth stirring, the speed of the fourth stirring is 50r / min-70r / min, and the stirring time is 10min-15min, so that the wolfberry extract and other ingredients are fully mixed to form a uniform mixture;

[0051] Step 4, thickening and flavoring: under continuous stirring, add the binder and stir again, the stirring speed of adding the binder and stirring again is increased to 50r / min-80r / min, the stirring time is 10min-15min, so that the toothpaste reaches the ideal consistency, that is, it has good plasticity and extrudability, and does not flow in a static state, and then add the flavoring agent and preservative for the final stirring, the stirring speed of adding the flavoring agent and preservative for the final stirring is reduced to 30r / min-50r / min, the stirring time is 5min-10min, ensure that the flavoring agent and preservative are evenly distributed in the toothpaste, so that the toothpaste has a pleasant smell and taste, and has good antiseptic properties;

[0052] Step 5, aging and filling: transfer the mixed toothpaste to a stainless steel aging tank with a sealed lid and age it at room temperature for 24-48 hours. Control the indoor temperature and relative humidity at 20-25°C and 40-60% to stabilize and even out the ingredients. During the aging process, the toothpaste needs to be gently stirred every 6-8 hours for 2-3 minutes each time to allow the ingredients to further penetrate each other and stabilize and even out. After aging, use a toothpaste filling machine to fill the toothpaste into a suitable packaging container and seal it for storage.

[0053] In the present invention, firstly, a combination of multiple raw materials such as wolfberry powder and pomegranate peel extract (containing vitamin K2) in specific proportions and pre-treated can not only bring into play the astringent and antibacterial properties of the nutrients in wolfberry and the pomegranate peel extract, which have a positive effect on preventing gingival atrophy, but also the basic ingredients such as abrasives, moisturizers, surfactants, etc. work synergistically, such as the abrasive providing appropriate cleaning power, the moisturizer maintaining the wetness of the toothpaste, etc., which can also effectively improve the cleaning and whitening effects of teeth.

[0054] In addition, wolfberry is rich in wolfberry polysaccharides, carotenoids, flavonoids and various minerals such as calcium and magnesium. Among them, wolfberry polysaccharides have immune regulation and antioxidant functions, which can reduce the inflammatory response of gingival tissue and provide protection for cells. Carotenoids and flavonoids can effectively remove free radicals, prevent gingival tissue from being damaged by oxidative stress, and help maintain the health of tooth enamel.

[0055] The tannin component in pomegranate peel extract has significant astringent and antibacterial properties. It can tighten gum tissue, reduce gum bleeding and inflammation, and inhibit the growth and reproduction of harmful bacteria in the mouth. Vitamin K2 plays a key role in regulating calcium metabolism. It promotes the deposition and utilization of calcium in gum tissue and teeth, enhances the toughness of gums and the hardness of teeth, effectively prevents gum atrophy and maintains the integrity of tooth structure.

[0056] The various nutrients in wolfberry are combined with tannins and vitamin K2 in pomegranate peel extract for a second time: First, at the antioxidant level, the carotenoids and flavonoids in wolfberry and the tannins in pomegranate peel extract jointly build a powerful antioxidant system, which greatly enhances the free radical scavenging ability, minimizes the damage of oxidative stress to gingival cells and tooth enamel, and provides comprehensive protection for oral health; secondly, in terms of gingival tissue repair and strengthening, the immunomodulatory effect of wolfberry polysaccharides and the antibacterial and anti-inflammatory effects of pomegranate peel extract cooperate with each other to reduce the incidence of inflammation and promote the repair of damaged tissues. healing; at the same time, vitamin K2 works synergistically with calcium, magnesium and other minerals in wolfberry to optimize the distribution and metabolism of calcium in the mouth, further strengthen the structure and function of gum tissue, and enhance the prevention of gum atrophy; furthermore, for the teeth whitening effect, the natural acidic components of wolfberry and the tannic acidic components in pomegranate peel extract complement each other, synergistically enhancing the ability to decompose dirt and pigments on the tooth surface, making the teeth whiter and brighter, and during the cleaning process, other ingredients work together to protect tooth enamel, prevent excessive wear and damage, and ensure that teeth remain healthy while cleaning and whitening.

[0057] The various nutrients in wolfberry, synergistic with the effective substances in pomegranate peel extract, can effectively prevent gum atrophy. Lycium barbarum polysaccharides can regulate immunity and anti-oxidation, and reduce gum inflammation. Pomegranate peel tannins are astringent and antibacterial, and vitamin K2 regulates calcium metabolism and strengthens gum toughness. Their secondary combination protects the gums from multiple aspects, reduces the risk of inflammation, promotes tissue repair, and optimizes calcium distribution. It can effectively prevent gum atrophy caused by age, bacterial infection and other factors, thereby reducing the risk of gum atrophy and maintaining gum health and tooth stability.

[0058] The natural acidic components of wolfberry and the tannic acidic components of pomegranate peel extract form a synergistic force, which can effectively decompose dirt and pigments on the surface of teeth, restoring the teeth to their whiteness and brightness. At the same time, during the cleaning process, other basic ingredients such as abrasives and moisturizers work synergistically to ensure cleaning power while effectively protecting tooth enamel and avoiding excessive wear, so that teeth can always remain healthy while achieving good cleaning and whitening effects, thereby improving the oral cleaning effect of wolfberry toothpaste.

[0059] According to different raw material dosages, the wolfberry toothpaste for preventing gum atrophy and whitening provided by the present invention is further described through the following specific examples.

[0060] Example 1

[0061] Raw material formula:

[0062] Wolfberry powder: the total amount is 5% of the total weight of toothpaste;

[0063] Pomegranate peel extract: the total amount is 5% of the total weight of toothpaste;

[0064] Abrasive (calcium carbonate): total amount is 23% of the total weight of toothpaste;

[0065] Moisturizer (glycerol: sorbitol = 1:1): total amount is 40% of the total weight of toothpaste;

[0066] Surfactant (sodium lauryl sulfate): total dosage is 1% of the total mass of toothpaste;

[0067] Binder (sodium carboxymethyl cellulose, viscosity 800 mPa·s): total amount is 0.5% of the total mass of toothpaste;

[0068] Flavoring agent (menthol): total amount is 0.5% of the total weight of toothpaste;

[0069] Preservative (sodium benzoate): total amount is 0.18% of the total mass of toothpaste;

[0070] Deionized water: balance;

[0071] Preparation method: The steps of the preparation method are as follows, namely, firstly preparing the raw materials, including pretreatment of wolfberry powder and screening of pomegranate peel extract; then preparing wolfberry extract; and then sequentially performing mixing, thickening and seasoning, aging and filling.

[0072] Example 2

[0073] Raw material formula:

[0074] Wolfberry powder: the total amount is 8% of the total weight of toothpaste;

[0075] Pomegranate peel extract: the total amount is 3% of the total weight of toothpaste;

[0076] Abrasive (silicon dioxide): total amount is 27% of the total weight of toothpaste;

[0077] Moisturizer (glycerol: sorbitol = 1.5:1): total amount is 33% of the total weight of toothpaste;

[0078] Surfactant (sodium lauryl sulfate): total dosage is 2% of the total weight of toothpaste;

[0079] Binder (sodium carboxymethyl cellulose, viscosity 1000mPa·s): total amount is 1.5% of the total weight of the toothpaste; Flavoring agent (essence): total amount is 0.6% of the total weight of the toothpaste;

[0080] Preservative (sodium benzoate): total amount is 0.15% of the total weight of toothpaste;

[0081] Deionized water: balance;

[0082] Preparation method: Same as the preparation steps in Example 1.

[0083] Example 3

[0084] Raw material formula:

[0085] Wolfberry powder: the total amount is 6% of the total weight of toothpaste;

[0086] Pomegranate peel extract: the total amount is 5% of the total weight of toothpaste;

[0087] Abrasive (calcium carbonate): total amount is 20% of the total weight of toothpaste;

[0088] Moisturizer (glycerol: sorbitol = 2:1): total amount is 37% of the total weight of toothpaste;

[0089] Surfactant (sodium lauryl sulfate): total dosage is 1.5% of the total weight of toothpaste;

[0090] Binder (sodium carboxymethyl cellulose, viscosity 1200mPa·s): total amount is 1.2% of the total weight of the toothpaste; Flavoring agent (menthol mixed with flavor): total amount is 0.8% of the total weight of the toothpaste;

[0091] Preservative (sodium benzoate): total dosage is 0.1% of the total weight of toothpaste;

[0092] Deionized water: balance;

[0093] Preparation method: Same as the preparation steps in Example 1.

[0094] Example 4

[0095] Raw material formula:

[0096] Wolfberry powder: the total amount is 3% of the total weight of toothpaste;

[0097] Pomegranate peel extract: the total amount is 4% of the total weight of toothpaste;

[0098] Abrasive (silicon dioxide): total amount is 30% of the total mass of toothpaste;

[0099] Moisturizer (glycerol: sorbitol = 1.8:1): total amount is 30% of the total weight of toothpaste;

[0100] Surfactant (sodium lauryl sulfate): total dosage is 3% of the total weight of toothpaste;

[0101] Binder (sodium carboxymethyl cellulose, viscosity 1100 mPa·s): total amount is 0.8% of the total mass of toothpaste;

[0102] Flavoring agent (flavor): the total amount is 1% of the total weight of toothpaste;

[0103] Preservative (sodium benzoate): total dosage is 0.2% of the total weight of toothpaste;

[0104] Deionized water: balance;

[0105] Preparation method: Same as the preparation steps in Example 1.

[0106] Table 1 Amount of each raw material used in Examples 1-4 (%)

[0107] Example 1 Example 2 Example 3 Example 4 Wolfberry powder (%) 5 8 6 3 Pomegranate peel extract (%) 5 3 5 4 Friction agent (%) 23 27 20 30 Moisturizer (%) 40 33 37 30 Surfactant (%) 1 2 1.5 3 Adhesive(%) 0.5 1.5 1.2 0.8 Flavoring agent (%) 0.5 0.6 0.8 1 preservative(%) 0.18 0.15 0.1 0.2 Deionized water (%) 24.82 24.75 28.4 28

[0108] In order to verify that the composite wolfberry toothpaste prepared in the embodiment of the present invention has good performance in preventing gum atrophy and whitening teeth, the wolfberry toothpaste for preventing gum atrophy and whitening teeth provided in the embodiment of the present invention is described through the following test examples.

[0109] Test example

[0110] The purpose of this experimental group is to explore the effects of different ingredient ratios on wolfberry toothpaste.

[0111] Test objectives: To detect the anti-gingival atrophy property, tooth whitening property, stability, cleanliness and ingredient compatibility of the wolfberry toothpaste material of the present invention.

[0112] Test method: Test group A, test group B, test group C and test group D respectively use the composition ratio of wolfberry toothpaste materials provided in Examples 1-4; the control example uses control group A, control group B, control group C and control group D, wherein:

[0113] Control group A

[0114] Raw material formula: the same as that of Example 1, except that the total amount of wolfberry powder is 3% of the total mass of the toothpaste, and the total amount of pomegranate peel extract is 1% of the total mass of the toothpaste;

[0115] Preparation method: Same as the preparation steps in Example 1.

[0116] Control group B

[0117] Raw material formula: the same as that of Example 1, except that the total amount of wolfberry powder is 10% of the total mass of the toothpaste, and the total amount of pomegranate peel extract is 8% of the total mass of the toothpaste;

[0118] Preparation method: Same as the preparation steps in Example 1.

[0119] Control group C

[0120] Raw material formula: the same as that of Example 1, but without adding pomegranate peel extract;

[0121] Preparation method: Same as the preparation steps in Example 1.

[0122] Control group D

[0123] Raw material formula: the same as that of Example 1, but without adding vitamin K2 to the pomegranate peel extract;

[0124] Preparation method: Same as the preparation steps in Example 1.

[0125] Specific detection indicators are shown in Table 2.

[0126] Table 2 Test indicators of each sample

[0127]

[0128]

[0129] According to Table 2 and Figure 2 As shown, a summary of the above comparative data is as follows:

[0130] By setting up test groups AD (corresponding to the proportions of wolfberry toothpaste ingredients in Examples 1-4, respectively) and control groups AD (adjusting the dosage or ingredients of wolfberry powder and pomegranate peel extract, respectively), several key indicators such as anti-gingival atrophy, tooth whitening, stability, cleanliness and ingredient compatibility were tested, and data results with significant differences were obtained, which fully demonstrated the important influence of each ingredient and its proportion in the present invention on the performance of toothpaste.

[0131] In terms of preventing gum atrophy, the performance of the test groups AD was significantly better than that of the control groups AD. The data of the test group was generally between 70% and 82%, while that of the control group was mostly between 50% and 68%. This shows that the specific ratio range of wolfberry powder and pomegranate peel extract (containing vitamin K2) determined by the present invention plays a key role in exerting its effect of preventing gum atrophy. For example, the amount of wolfberry powder and pomegranate peel extract in the control group A was lower than the required range of the invention, and its anti-gingival atrophy effect was only 50%, far lower than 80% of the test group A; the amount of both in the control group B was too high, and the good effect of the test group was not achieved, indicating that the appropriate raw material ratio is an important factor in ensuring the function of toothpaste in preventing gum atrophy.

[0132] There are also differences in the tooth whitening index between the test group and the control group. The data of the test group fluctuated between 72%-80%, while that of the control group was between 60%-70%. This reflects the positive effect of the synergistic effect of the natural acidic components of wolfberry and the tannic acidic components in the pomegranate peel extract on tooth whitening. When the pomegranate peel extract components are missing or the content is abnormal, such as in the control groups C and D, the tooth whitening index is relatively low, indicating that the pomegranate peel extract plays an indispensable role in improving the tooth whitening effect.

[0133] In terms of stability, the test group performed well overall, ranging from 88% to 95%, and the control group was able to reach 80% to 90%. This was mainly due to the rational use of basic ingredients such as moisturizers and adhesives and the scientific nature of the preparation process. However, the optimization of the proportions of each ingredient in the test group made the stability slightly better than some control groups. For example, the stability of test group C was as high as 95%, indicating that its raw material formula has certain advantages in maintaining the overall stability of toothpaste.

[0134] The cleaning index showed a similar pattern to other performances. The cleaning performance of the test group was 80%-90%, and that of the control group was 70%-82%. The abrasive, surfactant and other ingredients in the present invention cooperate with each other to effectively clean teeth, and the addition of wolfberry and pomegranate peel extracts not only does not affect the cleaning power, but also improves the overall cleaning effect through other synergistic effects, such as preventing excessive wear of tooth enamel.

[0135] In terms of ingredient compatibility, all test groups and control groups reached a high level, ranging from 90% to 98%. This shows that the raw materials selected by the present invention can be well integrated with each other after a specific preparation process to form a stable toothpaste system. However, different raw material ratios and ingredient changes will still have a certain subtle effect on compatibility. For example, due to the lack of vitamin K2 in the pomegranate peel extract, the ingredient compatibility of test group D is slightly lower than that of other test groups.

[0136] In summary, the ratio of wolfberry powder and pomegranate peel extract (containing vitamin K2) in the present invention and the synergistic effect between the ingredients play a key role in improving the anti-gingival atrophy property, tooth whitening property, stability, cleanliness and ingredient compatibility of wolfberry toothpaste, thereby improving the comprehensive performance and quality of wolfberry toothpaste.

[0137] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not intended to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A method for preparing a wolfberry toothpaste that prevents gum atrophy and whitens the teeth, characterized in that: The following steps are involved: S1. Raw material preparation: pre-treated wolfberry powder, pomegranate peel extract, abrasive, moisturizer, surfactant, adhesive, flavoring, preservative and deionized water; S2, preparation of wolfberry extract: adding wolfberry powder to 6-10 times the mass of 60%-70% ethanol solution, turning on the ultrasonic generator to extract the wolfberry powder, then filtering with a 200-300 mesh stainless steel filter, collecting the filtrate, and then transferring the filtrate to a vacuum concentration device, and concentrating it under reduced pressure to 1 / 5-1 / 3 of the original volume to obtain a concentrated wolfberry extract; S3, mixing and stirring: adding the moisturizer and deionized water into the stirring pot, turning on the stirrer for the first stirring, adding the friction agent after stirring evenly, stirring for the second time, then adding the surfactant and the pomegranate peel extract in sequence, stirring for the third time, and then adding the wolfberry extract for the fourth stirring; S4, thickening and seasoning: while stirring continuously, add the binder and stir again, then add the flavoring agent and preservative and stir for the final time; S5. Aging and filling: The mixed toothpaste is transferred to a stainless steel aging tank with a sealed lid and aged at room temperature. The temperature and relative humidity in the room are controlled by a temperature and humidity sensor to further stabilize and uniformize the ingredients. After aging, the toothpaste is filled into packaging containers using a toothpaste filling machine and sealed for storage.

2. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S1, the pretreatment of wolfberry powder uses high-quality dried wolfberries, which are fully washed with clean water and then placed in an oven for drying. The temperature is controlled at 60°C-70°C. During this period, the moisture content is monitored in real time by a moisture meter until the moisture content is lower than 5%. Subsequently, the dried wolfberries are crushed into 80-120 mesh fine powder using a grinder, and the powder is sealed and stored for later use.

3. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S1, the pomegranate peel extract at least includes vitamin K2, and the purity of the pomegranate peel extract is above 80%, and the vitamin K2 content is 1%-3%.

4. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S2, the ultrasonic frequency of the ultrasonic generator is 20kHz-40kHz, and the ultrasonic extraction is performed at 50°C-60°C for 30min-60min.

5. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S2, when the vacuum concentration device performs vacuum concentration, it is necessary to control the vacuum degree to 0.06MPa-0.09MPa and the temperature to 40°C-50°C.

6. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S3, the speed of the agitator for the first stirring is 30r / min-50r / min, and the stirring time is 5min-10min; the speed of the second stirring is 40r / min-60r / min, and the stirring time is 10min-15min; the speed of the third stirring is 30r / min-50r / min, and the stirring time is 6min-10min; the speed of the fourth stirring is 50r / min-70r / min, and the stirring time is 10min-15min.

7. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S4, the stirring speed of adding the binder for re-stirring is increased to 50 r / min-80 r / min, and the stirring time is 10 min-15 min; the stirring speed of adding the flavoring agent and preservative for the final stirring is reduced to 30 r / min-50 r / min, and the stirring time is 5 min-10 min.

8. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S5, the temperature and humidity sensor controls the indoor temperature at 20°C-25°C, the indoor relative humidity at 40%-60%, and the aging time at 24h-48h.

9. The method for preparing the multi-effect whitening wolfberry toothpaste for preventing gum atrophy according to claim 1, characterized in that: In S5, during the aging process, the toothpaste needs to be gently stirred every 6h-8h, and each stirring time is 2min-3min.

10. A multi-effect whitening wolfberry toothpaste for preventing gum atrophy prepared by the preparation method according to any one of claims 1 to 9, characterized in that: The following raw materials are included in weight percentage: Wolfberry powder, the total amount is 5%-9% of the total weight of toothpaste; Pomegranate peel extract, the total amount is 2%-6% of the total weight of the toothpaste; Abrasives, the total amount is 20%-30% of the total weight of toothpaste; Moisturizer, the total amount is 30%-40% of the total weight of toothpaste; Surfactants, the total amount is 1%-3% of the total weight of toothpaste; Adhesive, the total amount is 0.5%-1.5% of the total weight of toothpaste; Flavoring agent, the total amount is 0.5%-1% of the total weight of toothpaste; Preservatives, the total amount is 0.1%-0.2% of the total weight of toothpaste; Deionized water, balance.

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