Energy-saving blood glucose management system for establishing wireless communication connection based on signal intensity

Abstract

The invention discloses an energy-saving blood glucose management system for establishing wireless communication connection based on signal intensity, which is characterized in that a signal intensity threshold and a time threshold are preset in the blood glucose management system, timing is carried out during the period of establishing the wireless communication connection by a patient, a program module searches for nearby broadcast signals and identifies the signal intensity of the broadcast signals; if the broadcast of which the intensity is not less than the preset signal intensity threshold value is searched within the time threshold value, the program module can establish wireless communication connection with the detection module and / or the infusion module which send the broadcast signal without inputting the equipment identifier of the detection module and / or the infusion module; otherwise, the detection module and / or the infusion module adjust the broadcast signal sending parameters, including reducing the signal sending power and / or increasing the signal sending interval time, so that the reliability of establishing the wireless communication connection between the program module and the detection module and / or the infusion module of the patient is ensured, and meanwhile, the power consumption of the detection module and / or the infusion module is reduced.

Description

Technical Field

[0001] The present invention mainly relates to the field of medical devices, and in particular to an energy-saving blood glucose management system that establishes a wireless communication connection based on signal strength. Background Art

[0002] The pancreas of a normal person can automatically secrete the required insulin / glucagon according to the blood sugar level in the human body, thereby maintaining a reasonable blood sugar fluctuation range. However, the pancreatic function of diabetic patients is abnormal and cannot normally secrete the insulin required by the human body. Diabetes is a metabolic disease and a lifelong disease. Current medical technology cannot cure diabetes, and can only control the occurrence and development of diabetes and its complications by stabilizing blood sugar.

[0003] Diabetic patients need to test their blood sugar before injecting insulin into their bodies. Currently, most detection methods use in-vivo blood sugar detection devices to achieve continuous detection of blood sugar. In-vivo blood sugar detection devices use disposable transcutaneous sensors inserted into the skin to measure the blood sugar concentration in the interstitial fluid, and send blood sugar data to external devices in real time through wireless communication of the transmitter for patients to view. This detection method is called continuous blood sugar monitoring (CGM). The external device then sends the required insulin infusion amount to the insulin pump via wireless communication and injects insulin subcutaneously, thus forming a blood sugar management system.

[0004] In the prior art, before establishing a wireless communication connection between an external device (referred to as a program module in this solution) and a blood glucose detection device (referred to as a detection module in this solution) and / or an insulin pump (referred to as an infusion module in this solution), which are functional devices on the body, the patient often needs to input the device identifier of the blood glucose detection device and / or the insulin pump so that the external device can identify the broadcast signal of the blood glucose detection device and / or the insulin pump. The operation of inputting the device identifier is cumbersome and inconvenient for the patient. Even if some of the prior art adopts a solution of establishing a wireless communication connection without inputting the device identifier, the reliability of the wireless communication connection is not high because it cannot effectively distinguish the patient's own device from other patients' devices, and the long-term transmission of the broadcast signal consumes a lot of power for the device, which affects the service life of the device.

[0005] Therefore, the prior art urgently needs a blood glucose management system with high reliability and power saving that can establish a communication connection between an external device and a blood glucose detection device and / or an insulin pump without inputting a device identifier. Summary of the invention

[0006] An embodiment of the present invention discloses an energy-saving blood glucose management system for establishing a wireless communication connection based on signal strength. A signal strength threshold and a time threshold are preset in the blood glucose management system. During the period when a patient operates to establish a wireless communication connection, a program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast with an intensity not less than the preset signal strength threshold is found within the time threshold, the program module can establish a wireless communication connection with a detection module and / or an infusion module that sends the broadcast signal without inputting a device identifier of the detection module and / or the infusion module. Otherwise, the detection module and / or the infusion module adjusts the broadcast signal sending parameters, including reducing the signal sending power and / or increasing the signal sending interval time, thereby ensuring the reliability of the program module in establishing a wireless communication connection with the patient's own detection module and / or the infusion module, while reducing the power consumption of the detection module and / or the infusion module.

[0007] The present invention discloses a blood glucose management system, comprising an on-body functional module, which is pasted on the patient's skin surface and sends a broadcast signal to the outside world with a first parameter after being powered on; a program module, which is used to search for nearby broadcast signals and identify the signal strength of the broadcast signals, and the signal strength of the broadcast signal maps the distance between the program module and the on-body functional module; wherein a time threshold and a signal strength threshold are preset in the blood glucose management system, and the program module compares the broadcast signal strength with the preset signal strength threshold. If a broadcast signal with a signal strength not less than the preset signal strength threshold is searched within the preset time threshold, the program module establishes a wireless communication connection with the on-body functional module of the broadcast signal, otherwise, the on-body functional module sends the broadcast signal with a second parameter.

[0008] According to one aspect of the present invention, the on-body functional module includes a detection module and / or an infusion module, the detection module is used to continuously detect the patient's current blood sugar value, and the infusion module is used to infuse the currently required insulin into the patient's body.

[0009] According to one aspect of the present invention, the first parameter corresponds to a first power, the second parameter corresponds to a second power, and the second power is smaller than the first power.

[0010] According to one aspect of the present invention, when the on-body functional module sends a signal with a first power, when the searched broadcast signal strength is not less than a preset signal strength threshold, the distance between the program module and the on-body functional module is 0-0.5m.

[0011] According to one aspect of the present invention, when the on-body functional module sends a signal with a second power, when the searched broadcast signal strength is not less than a preset signal strength threshold, the distance between the program module and the on-body functional module is 0-0.1 m.

[0012] According to one aspect of the present invention, the second power is one half or one third of the first power.

[0013] According to one aspect of the present invention, the first parameter corresponds to a first time interval, the second parameter corresponds to a second time interval, and the first time interval is smaller than the second time interval.

[0014] According to one aspect of the present invention, the first time interval is 0.01-10 seconds, and the second time interval is 1-60 seconds.

[0015] According to one aspect of the present invention, the time threshold is 0-600 seconds.

[0016] According to one aspect of the present invention, it also includes codes corresponding to preset signal strength thresholds, each code corresponds to a different preset signal strength threshold, and the preset signal strength threshold can be set by inputting the code in the program module.

[0017] According to one aspect of the invention, the code is located in a device identifier of the on body function device.

[0018] According to one aspect of the present invention, the time threshold is set in an on-body function module or a program module.

[0019] According to one aspect of the present invention, the signal strength threshold is set in the program module.

[0020] According to one aspect of the present invention, the preset signal strength threshold is set in the on-body function module, and the broadcast signal includes information associated with the preset signal strength threshold.

[0021] According to one aspect of the present invention, when there is only one broadcast signal whose signal strength is not less than a preset signal strength threshold, the program module establishes a wireless communication connection with the on-body functional module that sends the broadcast signal; when there is more than one broadcast signal whose signal strength is not less than the preset signal strength threshold, the program module does not establish a wireless communication connection with the on-body functional module that sends the broadcast signal.

[0022] According to one aspect of the present invention, when the number of broadcast signals whose signal strength is not less than a preset signal strength threshold value is greater than one, the blood glucose management system prompts the patient to change the operation location or input the device identifier of the on-body functional module.

[0023] According to one aspect of the present invention, the program module further includes a signal correction coefficient, which is associated with the state of the program module. Before the program module compares the broadcast signal strength with a preset signal strength threshold, the broadcast signal strength is corrected based on the signal correction coefficient.

[0024] According to one aspect of the present invention, before the on-body function module and the program module establish a wireless communication connection, the patient's confirmation is required.

[0025] Compared with the prior art, the technical solution of the present invention has the following advantages:

[0026] In the blood glucose management system disclosed in the present invention, a signal strength threshold and a time threshold are preset in the blood glucose management system. When the power is turned on and the broadcast signal is sent outwardly, the program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast with an intensity not less than the preset signal strength threshold is found within the time threshold, the program module can establish a wireless communication connection with the detection module and / or infusion module that sends the broadcast signal without inputting the device identifier of the detection module and / or infusion module. Otherwise, the detection module and / or infusion module reduces the broadcast signal transmission power and / or increases the signal transmission time interval, thereby ensuring the reliability of the program module establishing a wireless communication connection with the patient's own detection module and / or infusion module, while reducing the power consumption of the detection module and / or infusion module.

[0027] Furthermore, the preset signal strength threshold may also be encoded in the device identifier of the detection module and / or infusion module, or printed on the detection module and / or infusion module or its packaging. Different codes correspond to different preset signal strength thresholds, and further correspond to different maximum distances for establishing a wireless communication connection, so as to facilitate further distinction from other patients' devices and ensure the reliability of establishing a wireless communication connection between the patient's device.

[0028] Furthermore, the program module can also identify the number of broadcast signals whose signal strength exceeds a preset signal strength threshold. When there is only one signal, the program module establishes a wireless communication connection with the detection module and / or the infusion module. When there is more than one signal, the program module does not establish a communication connection with the detection module and / or the infusion module to avoid the program module establishing a communication connection with the wrong detection module and / or infusion module. At the same time, the detection module and / or the infusion module can also prompt the patient to change the operation location to avoid other irrelevant broadcast signals as much as possible, thereby improving the reliability of establishing a wireless communication connection.

[0029] Furthermore, the preset signal strength threshold can be set in the program module, the detection module or the infusion module. When the preset signal strength threshold is set in the detection module or the infusion module, the preset signal strength threshold is transmitted together with the broadcast signal. When the program module receives the broadcast signal, it also receives the preset signal strength threshold. The program module can also compare the broadcast signal strength with the preset signal strength threshold, thereby establishing a wireless communication connection without inputting a device identifier. The preset signal strength threshold is set in the detection module or the infusion module and can be associated with the state of the detection module or the infusion module. Due to the differences in hardware of different individual detection modules or infusion modules, different preset signal strength thresholds need to be applied so that the patient can establish a wireless communication connection at a comfortable distance.

[0030] Furthermore, a signal correction coefficient is set in the program module. The sensitivity of the program module to signal strength recognition is not fixed for different program modules or as the program module is used for a longer time. The signal correction coefficient can correct the signal strength recognized by the program module to increase the accuracy of the program module's recognition of signal strength and increase the reliability of establishing a wireless communication connection. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 This is a schematic diagram of the relationship between modules of a general blood sugar management system;

[0032] Figure 2 is a schematic structural diagram of an integrated CGM according to an embodiment of the present invention;

[0033] Figure 3 is a schematic structural diagram of a split-type CGM according to an embodiment of the present invention;

[0034] Figure 4a is a schematic structural diagram of an integrated insulin pump according to an embodiment of the present invention;

[0035] Figure 4b A schematic diagram of the structure of a split-type insulin pump according to an embodiment of the present invention;

[0036] Figure 5a is a schematic diagram of a main interface when a control system according to an embodiment of the present invention is in a first working mode;

[0037] Figure 5b is a schematic diagram of a main interface when the control system according to an embodiment of the present invention is in a second working mode;

[0038] Figure 6a-6c Schematic diagram of different operations of turning on the insulin pump function according to the control system of an embodiment of the present invention;

[0039] Figure 7a-7c Schematic diagram of different operations of opening the automatic mode function of the control system according to an embodiment of the present invention;

[0040] Figure 8a-8b This is a schematic diagram of the APP interface before and after the automatic mode function is turned on in the control system according to an embodiment of the present invention;

[0041] FIG9a is a schematic diagram of an interface when a system turns on a meal mode according to an embodiment of the present invention;

[0042] 9b and 9c are schematic diagrams of different interfaces when selecting regular and feast in the feast mode of the system according to an embodiment of the present invention;

[0043] FIG9d is a schematic diagram of an interface when a regular meal mode is turned on by a system according to an embodiment of the present invention;

[0044] Fig.10 A schematic diagram of the process of the infusion strategy of pre-infusion and supplementary infusion according to an embodiment of the present invention;

[0045] Figures 11a-11f A schematic diagram of operations for establishing a wireless communication connection according to different embodiments of the present invention. DETAILED DESCRIPTION

[0046] As mentioned above, in the prior art, before establishing a wireless communication connection between an external device (referred to as a program module in this solution) and a blood glucose detection device (referred to as a detection module in this solution) and / or an insulin pump (referred to as an infusion module in this solution), which are functional devices on the body, the patient often needs to input the device identifier of the blood glucose detection device and / or the insulin pump so that the external device can identify the broadcast signal of the blood glucose detection device and / or the insulin pump. The operation of inputting the device identifier is cumbersome and inconvenient for the patient. Even if some of the prior art adopts a solution of establishing a wireless communication connection without inputting a device identifier, the reliability of the wireless communication connection is not high because it cannot effectively distinguish the patient's own device from other patients' devices, and the long-term transmission of the broadcast signal consumes a lot of power for the device, which affects the service life of the device.

[0047] In order to solve this problem, the present invention provides an energy-saving blood glucose management system that establishes a wireless communication connection based on signal strength. A signal strength threshold and a time threshold are preset in the blood glucose management system. When the power is turned on and the broadcast signal is sent out, the program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast with an intensity not less than the preset signal strength threshold is found within the time threshold, the program module can establish a wireless communication connection with the detection module and / or infusion module that sends the broadcast signal without inputting the device identifier of the detection module and / or infusion module. Otherwise, the detection module and / or infusion module adjusts the broadcast signal sending parameters, including reducing the signal sending power and / or increasing the signal sending interval time, thereby ensuring the reliability of the program module in establishing a wireless communication connection with the patient's own detection module and / or infusion module, while reducing the power consumption of the detection module and / or infusion module.

[0048] Various exemplary embodiments of the present invention will now be described in detail with reference to the accompanying drawings. It should be understood that the relative arrangement of components and steps, numerical expressions and numerical values ​​set forth in these embodiments should not be construed as limiting the scope of the present invention unless otherwise specifically stated.

[0049] In addition, it should be understood that for ease of description, the sizes of the various components shown in the drawings are not necessarily drawn according to actual proportions. For example, the thickness, width, length or distance of certain units may be enlarged relative to other structures.

[0050] The following description of the exemplary embodiments is merely illustrative and is not intended to limit the present invention and its application or use in any sense. Techniques, methods and devices known to ordinary technicians in the relevant field may not be discussed in detail here, but where applicable, these techniques, methods and devices should be considered as part of this specification.

[0051] It should be noted that like reference numerals and letters denote similar items in the following figures, and thus, once an item is defined or described in one figure, it will not require further discussion in the subsequent figure descriptions.

[0052] Figure 1 This is a schematic diagram of the relationship between modules of a general blood glucose management system.

[0053] The blood glucose management system disclosed in the embodiment of the present invention mainly includes a detection module 100 , a program module 101 and an infusion module 102 .

[0054] The detection module 100 is used to continuously detect the patient's current blood sugar level. Generally, the detection module 100 is a continuous glucose monitoring (CGM), which can detect the patient's current blood sugar level in real time, monitor blood sugar changes, and send the current blood sugar information to the program module 101. The CGM includes an implantable sensor, which is connected to a transmitter. The transmitter also includes a memory, a processor, a communication interface, etc. The transmitter is at least used to transmit the blood sugar data information detected by the CGM, as well as the identifier information of the CGM, etc.

[0055] The infusion module 102 includes mechanical structures and electronic control units necessary for infusing blood sugar regulating drugs such as insulin and glucagon, such as a drug storage cartridge, a drive structure, an infusion line and an infusion needle, a power supply, a circuit board, etc., and is controlled by the program module 101. Generally, the infusion module 102 is an insulin pump, and the electronic control unit includes a transmitter, a memory, a processor, a communication interface, etc. According to the current insulin infusion amount data sent by the program module 101, the infusion module 102 infuses the currently required insulin into the patient's body. At the same time, the infusion status of the infusion module 102 can also be fed back to the program module 101 in real time.

[0056] The program module 101 is used to control the work of the detection module 100 and the infusion module 102. At least according to the blood sugar value detected by the detection module 100, the program module 101 generates an insulin infusion instruction and controls the infusion module 102 to infuse, including a memory, a processor, a communication interface, a display, a patient interface, etc. The memory stores programming instructions, and the processor can execute the programming instructions in the memory. The program module 101 is connected to the detection module 100 and the infusion module 102 respectively. Here, the connection includes a conventional electrical connection or a wireless connection.

[0057] The embodiments of the present invention do not limit the specific positions and connection relationships of the detection module 100, the program module 101 and the infusion module 102, as long as the aforementioned functional conditions can be met.

[0058] For example, in one embodiment of the present invention, the three are electrically connected to form an integral structure. Therefore, the three are attached to the same position on the patient's skin. The three modules are connected as a whole and attached to the same position, and the number of devices attached to the patient's skin will be reduced, thereby reducing the interference of more devices attached to the patient's activities; at the same time, it also effectively solves the problem of wireless communication reliability between separate devices, further enhancing the patient experience.

[0059] In another embodiment of the present invention, the program module 101 and the infusion module 102 are connected to each other to form an integral structure, and the detection module 100 is separately arranged in another structure. In this case, the detection module 100 and the program module 101 transmit wireless signals to each other to achieve mutual connection. Therefore, the program module 101 and the infusion module 102 are attached to a certain position of the patient's skin, and the detection module 100 is attached to another position of the patient's skin.

[0060] In another embodiment of the present invention, the program module 101 and the detection module 100 are connected to each other to form the same device, and the infusion module 102 is separately arranged in another structure. The infusion module 102 and the program module 101 transmit wireless signals to each other to achieve mutual connection. Therefore, the program module 101 and the detection module 100 can be attached to a certain position of the patient's skin, and the infusion module 102 can be attached to another position of the patient's skin.

[0061] As in another embodiment of the present invention, the three are respectively arranged in different structures. Therefore, the three are respectively attached to different positions of the patient's skin. At this time, the program module 101 transmits wireless signals to the detection module 100 and the infusion module 102 to achieve mutual connection.

[0062] As in another embodiment of the present invention, the three are respectively arranged in different structures. Therefore, the detection module 100 and the infusion module 102 are respectively attached to different positions of the patient's skin, while the program module 101 does not need to be attached to the skin, and the detection module 100 and the infusion module 102 are controlled by a handheld or portable device, such as a PDM or a smart phone. At this time, the program module 101 transmits wireless signals to the detection module 100 and the infusion module 102 to achieve mutual connection. In the embodiment of the present invention, the detection module 100 and the infusion module 102 can be collectively referred to as an on-body functional module.

[0063] The wireless described in the foregoing embodiments may be, for example, but not limited to, radio frequency (RF) communication (e.g., radio frequency identification (RFID), Zigbee communication protocol, WiFi, infrared, wireless universal serial bus (USB), ultra-wideband (UWB), Communication protocols and cellular communications, such as Code Division Multiple Access (CDMA) or Global System for Mobile Communications (GSM).

[0064] Figure 2 Schematic diagram of the structure of an integrated CGM according to an embodiment of the present invention. Figure 3 Schematic diagram of the structure of a split-type CGM according to an embodiment of the present invention.

[0065] CGM includes a sensor and a transmitter, which are installed on the patient through an auxiliary installation device and inserted into the subcutaneous part. The sensor is used to collect blood sugar content in the human body and transmit the collected blood sugar content information. The transmitter is connected to the sensor and is used to receive the blood sugar data information transmitted by the sensor implanted subcutaneously and convert it into a wireless signal output. Each CGM has a unique identifier, such as a device identifier, a hardware identifier, a universal unique identifier, a serial number, an identifier based on a communication protocol (such as a BLE ID), a manufacturer's identifier, etc. The identifier is formed by a combination of multiple randomly combined numbers and letters, which can be set on the shell or packaging of the CGM, and can also have different settings for different types of CGM.

[0066] Figure 2 This is a schematic diagram of the structure of an integrated CGM. That is, the sensor and transmitter of the CGM are already integrated before use, and it is a disposable product that is discarded after use. Figure 2 As shown, the integrated CGM includes a sensor 201, a housing 202 and a transmitter (not shown) disposed in the housing 202. The sensor 301 is used to detect the patient's body fluid blood glucose data information, and transmit the blood glucose data information to the transmitter through the internal circuit, and then the transmitter sends it to the receiver. The identifier can be set on the outer shell or outer packaging of the CGM or inside the CGM.

[0067] Figure 3The structure diagram of the split CGM is shown in FIG. That is, before use, the sensor and transmitter of the CGM are two different components, which are packaged separately and integrated together when in use. The split CGM includes a bottom shell 301 and a transmitter 302. The bottom shell is provided with a sensor 3011. The transmitter 302 has a separate shell. The bottom shell 301 and the shell of the transmitter 302 are provided with snap-fit ​​structures 3012 and 3022 respectively. When in use, the bottom shell 301 and the transmitter 302 are snapped into a whole through the snap-fit ​​structure. The sensor 3011 is electrically connected to the transmitter 302 through the electrical connector 3013. The sensor 301 is used to detect the patient's blood sugar data information, and the above blood sugar data information is transmitted to the transmitter 302 through the electrical connector 3013, and then sent to the receiver by the transmitter 302.

[0068] In one embodiment of the present invention, the sensor and transmitter of the split CGM are both disposable products that are discarded after use, so the identifier can be set on the housing or outer packaging of the sensor or transmitter. In another embodiment of the present invention, only the sensor of the split CGM is a disposable product, and the transmitter is a reusable product. Therefore, preferably, in this embodiment, the identifier is set on the housing or outer packaging of the transmitter, which can reduce the binding frequency of patient information and the identifier and improve the patient experience. This will be described in detail below.

[0069] When the identifier is provided on the housing or outer packaging of the CGM or transmitter, it may be provided in a form including but not limited to a QR code, a barcode, or an NFC tag.

[0070] Figure 4a is a schematic structural diagram of an integrated insulin pump according to an embodiment of the present invention; Figure 4b Schematic diagram of the structure of a split-type insulin pump according to an embodiment of the present invention.

[0071] In an embodiment of the present invention, the insulin pump is a patch-type insulin pump, that is, an insulin pump that does not include a long catheter, includes an infusion structure and a control structure, and is adhered as a whole to the patient's skin surface by the same adhesive patch. The drug is directly infused from the drug storage cartridge along the infusion needle to the subcutaneous tissue.

[0072] Each insulin pump has a unique identifier, such as a device identifier, hardware identifier, universally unique identifier, serial number, communication protocol-based identifier, manufacturer's identifier, etc. The identifier is formed by a multi-digit random combination of numbers and letters, which can be set on the housing or packaging of the insulin pump, and can also have different settings for different types of insulin pumps.

[0073] Figure 4aIt is a schematic diagram of the structure of an integrated insulin pump, that is, the infusion structure 410 and the control structure 400 of the insulin pump are arranged inside the same housing 10, the two are connected by a wire, and are adhered to a certain position of the patient's skin through an adhesive patch 420, and are discarded as a whole after a single use; the identifier can be set on the outer housing or outer packaging of the insulin pump or inside the insulin pump.

[0074] Figure 4b This is a schematic diagram of the structure of a split insulin pump, that is, the infusion structure 410 and the control structure 400 of the insulin pump are respectively arranged in two different housings, and the two are connected by a waterproof plug or directly snapped and electrically connected to form a whole. The identifier can be set on the outer shell or outer packaging of the infusion structure and / or the control structure or inside the insulin pump.

[0075] In one embodiment of the present invention, the infusion structure and control structure of the split-type insulin pump are both disposable products, which are discarded after use, so the identifier can be set on the housing or outer packaging of the infusion structure and / or the control structure. In another embodiment of the present invention, only the infusion structure of the split-type insulin pump is a disposable product, and the control structure is a reusable product. Therefore, preferably, in this embodiment, the identifier is set on the housing or outer packaging of the control structure, which can reduce the binding frequency of patient information and the identifier and improve the patient experience. This will be described in detail below.

[0076] When the identifier is provided on the housing or outer packaging of the insulin pump or the control structure, it may be provided in a form including but not limited to a QR code, a barcode, or an NFC tag.

[0077] Depending on the different degrees of illness and the patients’ personal health conditions, some patients may only need CGM for continuous blood glucose testing, while some patients may not only need CGM for continuous blood glucose testing, but also need insulin pumps for drug infusions. When the doctor determines that the patient only needs to use CGM for continuous blood glucose testing, since CGM only involves the testing of the patient’s blood glucose, the patient’s self-use of CGM will not pose a risk to the patient’s life safety. Therefore, the patient can purchase CGM on his own. Before the CGM is installed on the patient’s skin surface, the patient can search and download a dedicated APP for controlling CGM in the smartphone’s application store, create a new account on the dedicated APP, and pair the patient’s personal information with the CGM information to be worn, thereby achieving pairing and control of the smartphone and CGM. The CGM and insulin pump in the embodiment of the present invention are developed and produced by the same manufacturer, so they can be controlled by the same dedicated APP in the smartphone. Since not all patients need to use the insulin pump, the default main screen of the dedicated APP only involves CGM-related content, such as Figure 5aAs shown, on the one hand, the interface of the APP can be simplified to provide patients with a better visual experience, and on the other hand, it can prevent patients from misoperating the insulin pump function and affecting the normal use of the CGM function.

[0078] In one embodiment of the present invention, when a doctor determines that a patient needs to use an insulin pump for drug infusion, such as Figure 6a As shown in the figure, the doctor sends an application to the backend administrator, requesting to add the patient account to the whitelist and allow the patient to use the insulin pump function. The backend administrator receives the whitelist addition application sent by the doctor, adds the patient account to the whitelist, and sends feedback to the doctor that the whitelist addition has been completed. Further, the backend administrator directly opens the insulin pump function of the APP interface used by the patient. At this time, the APP interface changes from Figure 5a become Figure 5b , Figure 5b Compared with Figure 5a The interface adds two function keys related to insulin infusion, "Insulin Delivery" and "Easyloop". In another embodiment of the present invention, the backend administrator does not directly open the insulin pump function of the APP interface used by the patient, but sends a security code to the patient account, and the patient can open the insulin pump function of the APP interface through the security code when needed or convenient.

[0079] In another embodiment of the present invention, when the doctor determines that the patient needs to use an insulin pump for drug infusion, such as Figure 6b As shown, the patient can directly send an application to the backend administrator to enable the insulin pump function. After receiving the application sent by the patient, the backend administrator will verify whether the patient's account is in the whitelist. If the patient's account is in the whitelist, the backend administrator will turn on the insulin pump function on the APP interface used by the patient. The APP interface changes from Figure 5a become Figure 5b ; If the patient account is not in the whitelist, feedback information is sent to the patient account to remind the patient to ask the doctor to send an application to add to the whitelist to the backend administrator. After the doctor sends the application to add to the whitelist to the backend administrator, the backend administrator can directly turn on the insulin pump function of the APP interface used by the patient. If no information from the backend administrator is received within a certain period of time, such as 1min, 2min, 5min, an application to turn on the insulin pump function can be sent to the backend administrator again, or the doctor can be asked to send an application to add to the whitelist to the backend administrator. In another embodiment of the present invention, the backend administrator does not directly turn on the insulin pump function of the APP interface used by the patient, but sends a security code to the patient account, and the patient can use the security code to turn on the insulin pump function of the APP interface when needed or convenient.

[0080] In another embodiment of the present invention, when the doctor determines that the patient needs to use an insulin pump for drug infusion, such as Figure 6c As shown, the doctor sends an application to the backstage administrator, requesting that the patient's account be added to the whitelist, allowing the patient to use the insulin pump function, the backstage administrator receives the application for adding the whitelist sent by the doctor, and adds the patient's account to the whitelist list, and sends feedback to the doctor that the whitelist addition has been completed. Further, the doctor notifies the patient that he can apply to use the insulin pump function; after receiving the doctor's notification, the patient sends an application to the backstage administrator to turn on the insulin pump function. After the backstage administrator receives the application for turning on the insulin pump function sent by the patient, the insulin pump function of the APP interface used by the patient is directly opened. In another embodiment of the present invention, after the backstage administrator receives the application for turning on the insulin pump function sent by the patient, it can also be verified whether the patient account exists in the whitelist. If it is determined that the patient account is in the whitelist list, the backstage administrator opens the insulin pump function of the APP interface used by the patient. In another embodiment of the present invention, the backstage administrator does not directly open the insulin pump function of the APP interface used by the patient, but sends a security code to the patient account. The patient can open the insulin pump function of the APP interface through the security code when needed or convenient.

[0081] When the doctor determines that the patient no longer needs to turn on the insulin pump function, the patient can turn off the insulin pump function on the APP by himself. The APP automatically sends information to the backend administrator, and the backend administrator deletes the patient account from the whitelist. The doctor and / or the patient can also send an application to the backend administrator to request to turn off the insulin pump function. The backend administrator turns off the insulin pump function on the patient account APP and deletes the patient account from the whitelist. When the patient needs to turn on the insulin pump function again, the patient account needs to refer to Figure 6a-6c One of the ways to add the whitelist again.

[0082] It should be noted that when the insulin pump function of the APP is turned on, it is necessary to ensure that the insulin pump is correctly installed on the skin, and the patient's personal information is paired with the information of the insulin pump, so as to achieve the pairing and control of the smart phone and the insulin pump. The patient's personal information includes name, age, gender, mobile phone number, etc., and the information of the CGM and / or insulin pump worn includes the identifier information of the CGM and / or insulin pump. At the same time, the smart phone uploads the patient's personal information and the identifier information of the CGM and / or insulin pump to the remote server. The remote server can store the information uploaded by the smart phone and verify whether the identifier information of the CGM and / or insulin pump is valid. If a certain identifier information already exists in the remote server, the remote server sends a prompt to the smart phone to remind the patient that the CGM or insulin pump has been used and needs to be replaced. When the CGM and / or insulin pump is installed on the patient's skin and successfully activated, the CGM and / or insulin pump starts working, the CGM transmitter sends the detected blood sugar information to the smart phone, and further uploads it to the remote server. The control structure of the insulin pump receives the insulin infusion information and controls the infusion structure to infuse insulin, and sends the infusion status to the smart phone at the same time, and further uploads it to the remote server.

[0083] It should be noted that the CGM and insulin pump in the embodiment of the present invention are developed and produced by the same manufacturer, and therefore can be controlled by the same dedicated APP in the smartphone. When the patient needs both CGM and insulin pump and CGM at the same time, even if the CGM or insulin pump is produced by other manufacturers, the CGM or insulin pump can be directly controlled by the dedicated APP, which can also avoid the inconvenience caused to the patient by using different APPs to control the CGM and insulin pump respectively, thereby improving the patient experience.

[0084] When the CGM and / or insulin pump worn by the patient needs to be replaced due to reaching the usage cycle or failure, the unique identifier information of the new CGM and / or insulin pump also needs to be paired and updated with the patient's personal information through the smartphone and further uploaded to the remote server. The patient's personal information is input manually, and the identifier information of the CGM and / or insulin pump can also be input manually or by scanning the QR code, barcode, or NFC tag on the shell or outer packaging of the CGM and / or insulin pump.

[0085] When the CGM has a split structure and the transmitter is reusable, the CGM identifier is set on the outer shell or packaging of the transmitter. When the patient changes the CGM, he only needs to replace the sensor without replacing the transmitter. The CGM identifier also remains unchanged. Therefore, there is no need to update the pairing of the CGM identifier and the patient's personal information through a smartphone, nor is there any need to upload it to a remote server. This can reduce the number of operating steps and improve the patient experience.

[0086] When the insulin pump has a split structure and the control structure is reusable, the identifier of the insulin pump is set on the outer shell or packaging of the control structure. When the patient replaces the insulin pump, he only needs to replace the infusion structure without replacing the control structure. The identifier of the insulin pump also remains unchanged. Therefore, there is no need to update the pairing of the insulin pump identifier and the patient's personal information through a smartphone, nor is there a need to upload it to a remote server. This can reduce the number of operating steps and improve the patient experience.

[0087] The smartphone and the CGM and / or insulin pump, as well as the remote server, communicate wirelessly, which may be accomplished by, for example, but not limited to, radio frequency (RF) communication (e.g., radio frequency identification (RFID), Zigbee communication protocol, WiFi, infrared, wireless universal serial bus (USB), ultra-wide band (UWB), Preferably, the smartphone and the remote server communicate via WiFi and / or cellular, and the smartphone and the CGM and / or insulin pump communicate via a wireless communication protocol and cellular communication, such as code division multiple access (CDMA) or global system for mobile communications (GSM). Communication protocol communication.

[0088] When the doctor determines that the patient can turn on the automatic mode, the APP reads the current blood sugar value detected by the CGM and the insulin information infused by the insulin pump, and can calculate the future blood sugar trend. Based on the calculated blood sugar trend, the insulin pump infusion is controlled, including increasing, decreasing, or stopping insulin infusion, in order to achieve the purpose of influencing the blood sugar value, forming an automatic closed-loop control cycle. Figure 7a As shown in the figure, the doctor sends an application to the backend administrator, requesting to add the patient account to the whitelist and allow the patient to use the automatic mode function. The backend administrator receives the whitelist addition application sent by the doctor, adds the patient account to the whitelist, and sends feedback to the doctor that the whitelist addition has been completed. Further, the automatic mode function of the APP interface used by the patient is directly turned on. At this time, the APP interface changes from Figure 8a become Figure 8b , Figure 8b Compared with Figure 8a The interface adds "Auto Mode", which is a function key related to the automatic mode. In another embodiment of the present invention, the backend administrator does not directly turn on the automatic mode function of the APP interface used by the patient, but sends a security code to the patient account, and the patient can turn on the automatic mode function of the APP interface through the security code when needed or convenient.

[0089] In another embodiment of the present invention, when the doctor determines that the patient can turn on the automatic mode, such as Figure 7bAs shown, the patient can directly send an application to the backend administrator to enable the automatic mode function. After receiving the application sent by the patient, the backend administrator will verify whether the patient's account is in the whitelist. If the patient's account is in the whitelist, the backend administrator will turn on the automatic mode function of the APP interface used by the patient. The APP interface changes from Figure 8a become Figure 8b ; If the patient account is not in the whitelist, feedback information is sent to the patient account to remind the patient to ask the doctor to send an application to add to the whitelist to the backend administrator. After the doctor sends the application to add to the whitelist to the backend administrator, the backend administrator can directly turn on the automatic mode function of the APP interface used by the patient. If no information from the backend administrator is received within a certain period of time, such as 1min, 2min, 5min, you can send an application to turn on the automatic mode function to the backend administrator again, or ask the doctor to send an application to add to the whitelist to the backend administrator. In another embodiment of the present invention, the backend administrator does not directly turn on the automatic mode function of the APP interface used by the patient, but sends a security code to the patient account, and the patient can use the security code to turn on the automatic mode function of the APP interface when needed or convenient.

[0090] In another embodiment of the present invention, when the doctor determines that the patient needs to use the automatic mode, such as Figure 7c As shown, the doctor sends an application to the backstage administrator, requesting that the patient's account be added to the whitelist, allowing the patient to use the automatic mode function. The backstage administrator receives the application for adding the whitelist sent by the doctor, and adds the patient's account to the whitelist list, and sends feedback to the doctor that the whitelist addition has been completed. Further, the doctor notifies the patient that he can apply to use the automatic mode function; after receiving the doctor's notification, the patient sends an application to turn on the automatic mode function to the backstage administrator. After receiving the application for turning on the automatic mode function sent by the patient, the backstage administrator directly turns on the automatic mode function of the APP interface used by the patient. In another embodiment of the present invention, after the backstage administrator receives the application for turning on the automatic mode function sent by the patient, it can also first verify whether the patient's account exists in the whitelist. If it is determined that the patient's account is in the whitelist list, the backstage administrator turns on the automatic mode function of the APP interface used by the patient. In another embodiment of the present invention, the backstage administrator does not directly turn on the automatic mode function of the APP interface used by the patient, but sends a security code to the patient account. The patient can turn on the automatic mode function of the APP interface through the security code when needed or convenient.

[0091] When the doctor determines that the patient no longer needs to turn on the automatic mode, the patient can turn off the automatic mode on the APP by himself, and the APP will automatically send a message to the backend administrator, who will delete the patient account from the whitelist. The doctor and / or the patient can also send an application to the backend administrator to request to turn off the automatic mode. The backend administrator will turn off the automatic mode on the patient account APP and delete the patient account from the whitelist. When the patient needs to turn on the automatic mode again, the patient account needs to refer to Figure 7a-7c One of the ways to add the whitelist again.

[0092] In the embodiment of the present invention, the security code sent by the background when applying for the insulin pump function and the automatic mode function can be any number or combination of a series of numeric characters, alphabetic characters and other symbols, and can also be a series of taps, a series of inputs, complex or simple gestures (e.g., sliding or other movements on a touch screen, drawing an image), etc. In some cases, the security code can also include a quiz or a set of questions. The security code sent by the background each time is random.

[0093] Since the dietary habits of people in different regions or at different ages vary greatly, the use of a unified control scheme may lead to poor blood sugar control for some people. Therefore, when the patient's automatic mode function is turned on, the patient is required to enter a pass code to enter different automatic mode interfaces. For people with high carbohydrate consumption, after entering the pass code, the automatic mode interface is shown in Figure 9a. The large meal option appears on the automatic mode interface, and the patient can choose whether to turn on the large meal module function. After the patient turns on the large meal mode function, the infusion page appears with two options, "Regular" and "Large Meal", as shown in Figures 9b and 9c. When the patient selects "Regular", the insulin infusion amount corresponding to the regular carbohydrate amount will be infused; when "Large Meal" is selected, the insulin infusion amount corresponding to the regular carbohydrate amount will be infused. For people with low carbohydrate consumption, after entering the pass code, the automatic mode interface is shown in Figure 9d. There is no large meal option on the interface, and the default is "Regular" mode, and the insulin infusion amount corresponding to the regular carbohydrate amount is infused.

[0094] In an embodiment of the present invention, the pass code may be a set of small questions, such as "Are you a carb lover?", "Is your age within the AB range?", "Your gender?", "Your place of residence?", "Your fitness hobbies?", "Do you have any special diseases?", "Have you used the non-automatic mode before turning on the automatic mode?", etc. Based on the patient's answers, the system automatically determines whether the patient is a person who consumes a lot of carbs. In other embodiments of the present invention, the pass code is informed in advance by the doctor after diagnosing the patient, or the doctor sends the information whether the patient is a person who consumes a lot of carbs while sending the automatic mode whitelist application to the backend administrator, and the backend administrator automatically assigns the patient a corresponding pass code. The pass code may be any number or combination of a series of numeric characters, alphabetic characters, and other symbols, or a series of taps, a series of inputs, complex or simple gestures (e.g., sliding or other movements on a touch screen, drawing an image), etc. The backend administrator may send the pass code to the patient when helping the patient turn on the automatic mode, or send the pass code to the patient at the same time as sending the security code, or send the pass code to the patient after confirming that the patient has turned on the automatic mode function through the security code. In the embodiment of the present invention, the security code and the pass code are both randomly generated, and their generation rules may be the same or different. Preferably, the generation rules of the security code and the pass code are different to avoid confusion and thus trouble for the patient.

[0095] In an embodiment of the present invention, the system or doctor determines whether a patient has a high carbohydrate consumption based on a comprehensive judgment of the patient's age, diet, exercise habits, health status, and non-automatic mode usage results. When the patient has a non-automatic mode usage record, the non-automatic mode usage record is used as the main basis for judgment.

[0096] After the patient selects a meal, including "regular" and "large meal", the automatic mode uses the drug infusion strategy of pre-infusion and supplementary infusion, such as Fig.10 In the case of pre-infusion and supplementary infusion, for regular meals and large meals, the pre-infusion amount and supplementary infusion amount are divided into different levels, as shown in the following Table 1:

[0097]

[0098]

[0099] Among them, the amount of insulin infused during pre-infusion is at least related to the actual blood sugar level or blood sugar change rate during pre-infusion, and the estimated meal size. In other embodiments of the present invention, the pre-infusion amount may also be related to IOB in the body; similarly, the amount of insulin infused during supplementary infusion is at least related to the actual blood sugar level or blood sugar change rate during supplementary infusion, and the estimated supplementary meal size. In other embodiments of the present invention, the supplementary infusion amount may also be related to IOB in the body. In the embodiments of the present invention, the meal size refers to the carbohydrate content contained in the meal.

[0100] The large, medium and small meal sizes corresponding to pre-infusion and the large, medium and small meal sizes corresponding to supplementary infusion are all independent parameters. The meal size corresponding to the same level of pre-infusion is larger than the meal size corresponding to supplementary infusion, but there is not necessarily a fixed corresponding relationship between the two. The system can be set according to actual needs. For large meals, the minimum meal size corresponding to pre-infusion is not less than the maximum meal size corresponding to regular meals, and the minimum meal size corresponding to supplementary infusion is not less than the maximum meal size corresponding to regular meals.

[0101] Step 1001, the patient selects the meal type at time T0 and pre-infuses a default insulin infusion amount. The default insulin infusion amount for pre-infusion can be the pre-infusion insulin infusion amount corresponding to any small, medium or large meal size. Preferably, the default insulin infusion amount for pre-infusion is the insulin infusion amount corresponding to a small meal size. Selecting a small amount of supplementary insulin infusion can prevent excessive insulin infusion and reduce the risk of hypoglycemia.

[0102] Step 1002, at time T1, compare the current blood glucose value detected by CGM with the preset blood glucose threshold, such as 140, 150, 160, 170, 180, 190, 200 mg / mL, etc. If the current blood glucose value is greater than the preset blood glucose threshold, the default supplementary insulin infusion amount is infused, otherwise, the supplementary infusion amount is not infused, wherein the default supplementary infusion amount is the supplementary infusion insulin infusion amount corresponding to any small, medium or large meal size, preferably, the default supplementary infusion insulin infusion amount is the insulin infusion amount corresponding to the small meal size, and selecting a small initial supplementary insulin infusion amount can prevent excessive insulin infusion and reduce the risk of hypoglycemia. Time T1 may be 1h, 1.5h, 2h, 2.5h, 3h, etc. after time T0. In other embodiments of the present invention, it can also be determined whether to perform supplementary infusion in combination with the blood glucose change rate at time T1.

[0103] Step 1003, within the △T0 time after the T0 moment, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, the next pre-infusion is upgraded, that is, the insulin infusion amount corresponding to the larger estimated meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next pre-infusion moment is considered; if the patient has hypoglycemia, the next pre-infusion is downgraded, that is, the insulin infusion amount corresponding to the smaller estimated meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next pre-infusion moment is considered; if the patient has neither hyperglycemia nor hypoglycemia, the next pre-infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next pre-infusion moment is considered.

[0104] It should be noted that, in the embodiment of the present invention, the change in the infusion level means the change in the level of the estimated meal amount during infusion, while taking into account the actual blood glucose value or blood glucose change rate at the time of infusion, or the IOB in the body. Therefore, in the embodiment of the present invention, the change in the estimated meal amount level also means the change in the infusion level, that is, the infusion level and the estimated meal amount level can be understood to be consistent.

[0105] Step 1004, within the △T1 time after the T1 moment, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, the next supplementary infusion is upgraded, that is, the supplementary insulin infusion amount corresponding to the larger estimated meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next supplementary infusion time is taken into consideration; if the patient has hypoglycemia, the next supplementary infusion is downgraded, that is, the insulin infusion amount corresponding to the smaller estimated supplementary meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next supplementary infusion time is taken into consideration; if the patient has neither hyperglycemia nor hypoglycemia, the next supplementary infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same supplementary estimated meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next supplementary infusion time is taken into consideration.

[0106] In step 1005, the patient selects a meal type at time T2 and pre-infuses according to the result of step 1003, i.e., pre-infuses a larger, smaller, or unchanged insulin infusion amount corresponding to the estimated meal size, while taking into account the actual blood glucose value or blood glucose change rate, or IOB in the body at time T2.

[0107] Step 1006, at time T3, compare the current blood glucose value detected by CGM with the preset blood glucose threshold, such as 140, 150, 160, 170, 180, 190, 200 mg / mL, etc. If the current blood glucose value is greater than the preset blood glucose threshold, then supplementary infusion is performed according to the result of step 1004, that is, a larger, smaller or unchanged supplementary meal amount corresponding to the insulin infusion amount is supplemented, and the actual blood glucose value or blood glucose change rate at time T3, or the IOB in the body is considered at the same time. If the current blood glucose value is not greater than the preset blood glucose threshold, no supplementary infusion is performed. In other embodiments of the present invention, it can also be determined whether to perform supplementary infusion in combination with the blood glucose change rate at time T3.

[0108] Step 1007, within the △T0 time after the T2 moment, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, the next pre-infusion is upgraded, that is, the insulin infusion amount corresponding to the larger estimated meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next pre-infusion moment is considered; if the patient has hypoglycemia, the next pre-infusion is downgraded, that is, the insulin infusion amount corresponding to the smaller estimated meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next pre-infusion moment is considered; if the patient has neither hyperglycemia nor hypoglycemia, the next pre-infusion level remains unchanged, that is, the insulin infusion amount corresponding to the same meal amount is infused, and the actual blood glucose value or blood glucose change rate, or the IOB in the body at the next pre-infusion moment is considered.

[0109] Step 1008, within the △T1 time after the T3 moment, such as 3h, 4h, 5h, etc., if the patient has hyperglycemia, the next supplementary infusion is upgraded, that is, a larger supplementary insulin infusion amount corresponding to the estimated meal amount is infused, and the actual blood sugar value or blood sugar change rate, or the IOB in the body at the next supplementary infusion time is taken into consideration; if the patient has hypoglycemia, the next supplementary infusion is downgraded, that is, a smaller supplementary insulin infusion amount corresponding to the estimated meal amount is infused, and the actual blood sugar value or blood sugar change rate, or the IOB in the body is taken into consideration at the next supplementary infusion time; if the patient has neither hyperglycemia nor hypoglycemia, the next supplementary infusion level remains unchanged, that is, the same supplementary meal amount is infused, and the actual blood sugar value or blood sugar change rate, or the IOB in the body is taken into consideration at the next supplementary infusion time.

[0110] When pre-infusion and supplemental infusion are required at the next moment, steps 1005-1008 are repeated.

[0111] Generally, in order to maintain the stability of the patient's blood sugar level, the meal type selected by the patient at T2 and T0 is consistent, that is, if the patient chooses a regular meal at T0, then he will also choose a regular meal at T2. If he chooses a large meal at T0, then he will also choose a large meal at T2. Therefore, the next pre-infusion insulin selection and supplementary insulin infusion selection can depend on the results of the previous pre-infusion insulin selection and supplementary insulin infusion selection. However, if the patient's next meal selection is inconsistent with the previous meal selection, the patient will restore to the initial default pre-infusion amount and default supplementary infusion amount at the next pre-infusion and supplementary infusion time to prevent inaccurate insulin infusion amount due to changes in meal patterns.

[0112] Here, it should be noted that if the meal size corresponding to the current pre-infusion amount is already the largest meal size in the selected meal type, if hyperglycemia still occurs within the △T0 time after T0, the next pre-infusion amount will not be upgraded, and the insulin infusion amount corresponding to the large estimated meal size will still be pre-infused, while considering the actual blood sugar value or blood sugar change rate at the next pre-infusion time, or the IOB in the body. Similarly, if the meal size corresponding to the current pre-infusion amount is already the smallest meal size in the selected meal type, if hypoglycemia still occurs within the △T0 time after T0, the next pre-infusion amount will not be downgraded, and the insulin infusion amount corresponding to the small estimated meal size will still be pre-infused, while considering the actual blood sugar value or blood sugar change rate at the next pre-infusion time, or the IOB in the body.

[0113] Similarly, if the meal size corresponding to the current supplementary infusion amount is already the largest meal size in the selected meal type, if hyperglycemia still occurs within the △T0 time after T0, the next supplementary infusion amount will not be upgraded, and the insulin infusion amount corresponding to the large supplementary estimated meal size will still be pre-infused, while considering the actual blood sugar value or blood sugar change rate at the next supplementary infusion, or the IOB in the body. Similarly, if the meal size corresponding to the current supplementary infusion amount is already the smallest supplementary meal size in the selected meal type, if hypoglycemia still occurs within the △T0 time after T0, the next supplementary infusion amount will not be downgraded, and the insulin infusion amount corresponding to the small supplementary estimated meal size will still be pre-infused, while considering the actual blood sugar value or blood sugar change rate at the next supplementary infusion, or the IOB in the body.

[0114] In other embodiments of the present invention, the meal sizes corresponding to pre-infusion and supplementary infusion are not necessarily graded, that is, the estimated meal size during pre-infusion may only be a default size, while during supplementary infusion, the estimated meal size may be three different levels of large, medium and small. Therefore, during the pre-infusion stage, each pre-infusion only infuses the insulin infusion amount corresponding to the default meal size; or the estimated meal size during pre-infusion may be three different levels of large, medium and small, while during supplementary infusion, the estimated meal size may only be the default size. Therefore, during supplementary infusion, each supplementary infusion only infuses the insulin infusion amount corresponding to the default meal size.

[0115] Similarly, the settings for the estimated meal sizes corresponding to pre-infusion and supplementary infusion in large meals and regular meals are not necessarily consistent, that is, for each meal mode, the estimated meal sizes corresponding to pre-infusion and supplementary infusion can be selected as graded or ungraded (default amount), and can be set according to the actual needs of the patient.

[0116] In an embodiment of the present invention, a small meal mode, namely a snack mode, is also provided in the system. When the patient selects the snack mode, since the carbohydrate content range in snacks is relatively small, the system performs insulin infusion based on the default estimated meal amount, while taking into account the patient's actual blood sugar value or blood sugar change rate when eating snacks, as well as the IOB in the body. Moreover, the default estimated meal amount in the snack mode is smaller than the lowest level estimated meal amount in the regular mode.

[0117] Establishing a wireless communication connection

[0118] Figures 11a-11f Schematic diagram of operations for establishing a wireless communication connection according to different embodiments of the present invention.

[0119] In the blood glucose management system, when the program module 101 is an external device such as a smart phone, PDM or tablet computer, in order to facilitate the patient to use the artificial pancreas system, wireless communication is used for data transmission and interaction between the on-body functional module (detection module 100 and / or infusion module 102). Before the wireless communication connection is formally established, the detection module 100 and / or infusion module 102 sends a broadcast signal, and the program module 101 searches for the broadcast signal and identifies the content and signal strength of the broadcast signal.

[0120] In the prior art, the patient needs to obtain the unique device identifier of the detection module 100 and / or the infusion module 102, and input the device identifier into the program module 101, so as to identify the broadcast signal of the detection module 100 and / or the infusion module 102 and establish a wireless communication connection. This step may be troublesome, time-consuming and laborious for the patient. Therefore, some detection modules 100 or infusion modules 102 can send broadcast signals before establishing a communication connection. When the program module 101 searches for these broadcast signals, it can directly establish a communication connection with the signal source. This method saves the patient from the step of inputting the device identifier of the detection module 100 and / or the infusion module 102, and is convenient for the patient to use. However, when the patient is in a complex usage environment, for example, the patient is in a hospital, clinic, or other place where multiple patients are likely to gather, the patient's program module 101 may search for broadcast signals from other patients' detection modules 100 and / or infusion modules 102 when searching for broadcast signals from the detection module 100 and / or infusion module 102. The patient's program module 101 may therefore be connected to the wrong detection module 100 and / or infusion module 102, which may cause the patient's program module 101 to receive blood sugar test data from other patients, or send erroneous infusion instructions to other patients' infusion modules 102, while the patient's own infusion module 102 cannot receive the correct infusion instructions, which is disadvantageous to the patient.

[0121] In view of the above problems, in some embodiments of the present invention, it is considered that when the patient establishes a wireless communication connection between his own program module 101 and the detection module 100 and / or infusion module 102, the patient will inevitably place the program module 101 and the detection module 100 and / or infusion module 102 next to him, that is, the patient's own detection module 100 and / or infusion module 102 is shorter than the detection modules 100 and / or infusion modules 102 of other patients and the patient's own program module 101. Then, when the program module 101 searches for the broadcast signal of the patient's own detection module 100 and / or infusion module 102, the signal strength it obtains is stronger, and if the patient intends to make his own program module 101 search for a stronger broadcast signal strength to distinguish it from the broadcast signals of other patients, the patient can also actively place his own program module 101 close to his own detection module 100 and / or infusion module 102. The specific implementation is described below.

[0122] When the program module 101 establishes a wireless communication connection with the detection module 100 and / or the infusion module 102, Bluetooth is generally used as a communication protocol. According to the following calculation formula of Bluetooth signal strength and distance, the distance between the program module 101 and the detection module 100 and / or the infusion module 102 can be mapped according to the Bluetooth signal strength searched by the program module 101.

[0123]

[0124] Where:

[0125] d is the distance between the program module 101 and the detection module 100 and / or the infusion module 102;

[0126] RSSI is the signal strength received by the program module 101, which is a negative value;

[0127] A is the signal strength received when the program module 101 is 1 meter away from the detection module 100 and / or the infusion module 102;

[0128] n is the environmental attenuation factor.

[0129] According to calculation formula (1), the distance d between the program module 101 and the detection module 100 and / or the infusion module 102 can be determined according to the signal strength received by the program module 101. The stronger the broadcast signal strength received by the program module 101, the smaller the value of the distance d, which means that the patient's program module 101 is closer to the detection module 100 and / or the infusion module 102. Conversely, when the patient holds the program module 101 close to his own detection module 100 and / or the infusion module 102, the broadcast signal strength of the program module 101 searching for his own detection module 100 and / or the infusion module 102 gradually increases, and at the same time, the broadcast signal strength of the detection module 100 and / or the infusion module 102 of other patients gradually decreases. Based on this, the program module 101 can distinguish the patient's own detection module 100 and / or the infusion module 102 from the detection modules 100 and / or the infusion modules 102 of other patients, and avoid establishing a wireless communication connection with the wrong detection module 100 and / or the infusion module 102.

[0130] Generally speaking, for the detection module 100 or the infusion module 102, as long as its model and parameters do not change, the power of the broadcast signal sent is fixed after it is powered on at the factory, and the signal strength of the broadcast signal decreases with the distance according to calculation formula (1). Therefore, when the program module 101 searches for the broadcast signal, the relative distance between the program module 101 and the detection module 100 or the infusion module 102 can be obtained based on the signal strength of the identified broadcast signal.

[0131] It should be noted that the above calculation formula (1) is only used as an exemplary description of signal strength and relative distance in this solution, and other calculation methods may be combined or used in actual product applications.

[0132] Reference Fig.11a In some embodiments of the present invention, a signal strength threshold RSSI may be preset in the program module 101. T, the broadcast signal corresponding to the signal strength threshold RSSI of the detection module 100 T100 , the broadcast signal of the infusion module 102 corresponds to the signal strength threshold RSSI T102 When the patient operates the program module 101 to move it closer to the detection module 100 and / or the infusion module 102, the signal strength RSSI received by the program module 101 gradually increases until it is not less than the preset signal strength threshold RSSI. T100 and / or RSSI T102 When the patient receives the detection module 100 and / or the infusion module 102, it can be considered that the signal source of the signal is the patient's own detection module 100 and / or the infusion module 102. At this time, the patient no longer needs to input the device identifier of the detection module 100 and / or the infusion module 102, that is, the program module 101 can directly establish a wireless communication connection with the detection module 100 and / or the infusion module 102, which is convenient for the patient to use.

[0133] In some other embodiments of the present invention, the signal strength threshold RSSI may also be preset in the detection module 100. T100 And / or preset the signal strength threshold RSSI in the infusion module 102 T102 When the detection module 100 and / or the infusion module 102 sends a broadcast signal, the broadcast signal carries a signal strength threshold RSSI T100 and / or RSSI T102 After searching for the broadcast signal, the program module 101 identifies the strength of the broadcast signal and also identifies the preset signal strength threshold RSSI carried in the broadcast signal. T100 and / or RSSI T102 , and then compare the signal strength of the broadcast signal with the preset signal strength threshold RSSI T100 and / or RSSI T102 If the signal strength of the broadcast signal is not less than the preset signal strength threshold RSSI, T100 and / or RSSI T102 , indicating that the detection module 100 and / or infusion module 102 that sent the broadcast signal is close to the program module 101. It can be considered that the signal source of the signal is the patient's own detection module 100 and / or infusion module 102. At this time, the patient no longer needs to input the device identifier of the detection module 100 and / or infusion module 102, that is, the program module 101 can directly establish a wireless communication connection with the detection module 100 and / or infusion module 102, which is convenient for the patient to use. When the detection module 100 and / or infusion module 102 is produced, the preset signal strength threshold RSSI T100 and / or RSSI T102Set in the detection module 100 and / or the infusion module 102, the preset signal strength threshold RSSI suitable for the detection module 100 and / or the infusion module 102 can be set according to the hardware status, type, parameters and other characteristics of the detection module 100 and / or the infusion module 102. T100 and / or RSSI T102 The detection modules 100 and / or infusion modules 102 with different hardware status, types, parameters and other characteristics have different powers for sending broadcast signals. Thus, when the patient operates to establish a wireless communication connection, the maximum distance between the program module 101 and the detection module 100 and / or infusion module 102 is also different. In order to increase the patient's operating convenience and maintain consistency of habits, a preset signal strength threshold RSSI suitable for the detection module 100 and / or infusion module 102 is set. T100 and / or RSSI T102 , which can ensure that when the patient is operating to establish a wireless communication connection, the distance between the program module 101 and the detection module 100 and / or the infusion module 102 is appropriate and consistent, thereby increasing the operational convenience for the patient and improving the patient's user experience.

[0134] In some embodiments of the present invention, establishing a wireless communication connection by using the program module 101 to identify the signal strength sent by the detection module 100 and / or the infusion module 102 does not necessarily mean that the blood glucose management system turns off inputting the device identifier of the detection module 100 and / or the infusion module 102 to establish a wireless communication connection. The two methods of establishing a wireless communication connection may coexist, and the patient may choose the appropriate method based on his or her own condition.

[0135] Reference Fig.11b In some embodiments of the present invention, the blood glucose management system provides two operation modes for establishing wireless communication connection for the patient at the same time. In the first operation mode, the patient operates the program module 101 to approach the detection module 100 and / or the infusion module 102. As mentioned above, the program module 101 identifies the signal strength sent by the detection module 100 and / or the infusion module 102 to establish a wireless communication connection. In the second operation mode, the patient inputs the device identifier of the detection module 100 and / or the infusion module 102 in the program module 101. The device identifier includes the broadcast signal information of the detection module 100 and / or the infusion module 102. Based on the device identifier, the corresponding broadcast signal can be identified to establish a wireless communication connection.

[0136] In some embodiments of the present invention, the program module 101 obtains the device identifier in ways including but not limited to manual character input by the patient, scanning of a QR code, Bluetooth transmission, voice recognition, etc. Any method that can input the device identification code into the program module 101 can implement this solution.

[0137] In some embodiments of the present invention, when a patient desires to establish a wireless communication connection, the patient may select the first operating mode or the second operating mode on the interactive interface of the program module 101 , and the first operating mode and the second operating mode are displayed in parallel on the interactive interface of the program module 101 .

[0138] In some embodiments of the present invention, the detection module 100 and / or the infusion module 102 may be an integrated or split structure. When the detection module 100 is a split structure, its transmitter is reusable. When the infusion module 102 is a split structure, its electronic control unit, such as Figure 4a and 4b The control structure 100 shown in FIG. 1 is reusable. In the embodiment of the present invention, the device identifier of the detection module 100 corresponds to its transmitter, and the device identifier of the infusion module 102 corresponds to its electronic control unit.

[0139] In the first operation mode, the broadcast signal carries information associated with the device identifier, and the program module 101 can obtain the device identifier information carried by the broadcast signal while identifying the broadcast signal. After the patient successfully operates to establish a wireless communication connection, the program module 101 generates a whitelist profile that can establish a wireless communication connection object. The whitelist profile stores relevant information of the detection module 100 and / or the infusion module 102 that have established a wireless communication connection, such as storing the device identifier of the detection module 100 and / or the infusion module 102. If the patient operates again to establish a wireless communication connection with the old detection module 100 and / or the infusion module 102 without replacing the transmitter and the electronic control unit, the program module 101 only needs to identify the device identifier information carried in the broadcast signal. If it is consistent with the device identifier stored in its whitelist profile, the program module 101 can directly establish a wireless communication connection with the detection module 100 and / or the infusion module 102 that sent the broadcast signal, without the need to enter the device identifier again, and without the need to identify the signal strength of the broadcast signal, which is convenient for the patient to operate and improves the user experience.

[0140] In some embodiments of the present invention, the whitelist profile of the program module 101 may store one or more device identifiers.

[0141] In some embodiments of the present invention, when the patient no longer wishes to establish a wireless communication connection with an old detection module 100 and / or infusion module 102, the patient may choose to modify or delete the corresponding whitelist profile, so that the program module 101 will not be able to directly establish a wireless communication connection with the detection module 100 and / or infusion module 102. After the patient modifies or deletes the whitelist profile, if the patient needs to establish a wireless communication connection with the corresponding detection module 100 and / or infusion module 102 again, the first operation mode or the second operation mode needs to be performed again.

[0142] In other embodiments of the present invention, when the patient operates again to establish a wireless communication connection, the patient may also choose to use the first operation mode or the second operation mode, and the patient is not restricted.

[0143] In some embodiments of the present invention, the program module 101 just searches for a signal with a preset signal strength threshold RSSI. T100 and / or RSSI T102 When the broadcast signals are of the same strength, the distance between the program module 101 and the detection module 100 and / or the infusion module 102 is the maximum distance for establishing a wireless communication connection. If there is no change in the signal propagation medium, the program module 101 can establish a wireless communication connection with the detection module 100 and / or the infusion module 102 at any position within this maximum distance.

[0144] In some embodiments of the present invention, the broadcast signal strength threshold RSSI transmitted by the detection module 100 and / or the infusion module 102 is set. T100 and / or RSSI T102 The corresponding maximum distance, for example, can be set to a maximum distance of 0.5 m for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102, that is, when the distance between the program module 101 and the detection module 100 and / or the infusion module 102 does not exceed 0.5 m, the patient does not need to input the device identifier of the detection module 100 and / or the infusion module 102 to establish a wireless communication connection. Preferably, the above maximum distance is 0.3 m. Further preferably, the above maximum distance is 0.1 m. In the embodiment of the present invention, the smaller the distance between the program module 101 and the detection module 100 and / or the infusion module 102, the stronger the signal strength of the program module 101 identifying the patient's own detection module 100 and / or the infusion module 102, and the easier it is to distinguish from the device signals of other patients. The reliability of establishing a wireless communication connection between the program module 101 and the patient's own detection module 100 and / or the infusion module 102 is higher. If the distance between the program module 101 and the detection module 100 and / or the infusion module 102 is too small, it may result in low operational convenience for the patient. Selecting an appropriate signal strength threshold can determine the appropriate distance for connecting the wireless communication connection.

[0145] In the above embodiment, when the broadcast signal strength sent by the detection module 100 and / or the infusion module 102 after being powered on is the same, and the signal strength threshold RSSI preset in the program module 101 is T100 and / or RSSI T102When the distance between the patient's own detection module 100 and / or infusion module 102 and the patient's own detection module 100 and / or infusion module 102 is unchanged, the maximum distance between the patient's own detection module 100 and / or infusion module 102 and the patient's own detection module 100 and / or infusion module 102 is the same each time the patient establishes a wireless communication connection. In other embodiments of the present invention, the maximum distance between the patient's own detection module 100 and / or infusion module 102 and the patient's own detection module 100 and / or infusion module 102 can be adjusted.

[0146] For example, refer to Fig.11c In some embodiments of the present invention, the signal strength threshold RSSI T100 and / or RSSI T102 The signal strength threshold RSSI in different program modules 101 is pre-stored in the program module 101 when the program module 101 is produced. T100 and / or RSSI T102 The preset value may be different. When the patient is operating to establish a wireless communication connection, the maximum distance at which the program module 101 identifies the patient's own detection module 100 and / or infusion module 102 is therefore different. When the patient operates the program module 101 to approach the detection module 100 and / or infusion module 102, after entering this maximum distance, a wireless communication connection can be established between the program module 101 and the detection module 100 and / or infusion module 102.

[0147] Alternatively, in some other embodiments of the present invention, the available signal strength threshold RSSI T100 and / or RSSI T102 The signal strength threshold RSSI suitable for the state of the detection module 100 and / or the infusion module 102 is pre-stored in the program module 101 in the form of a list profile, and when the detection module 100 and / or the infusion module 102 are shipped, T100 and / or RSSI T102 The code is in the device identifier. Such a code may consist of at least one digit, letter, special symbol, etc. Before the patient operates to establish a wireless communication connection, he or she may first input the signal strength threshold RSSI through the interactive interface of the program module 101. T100 and / or RSSI T102 The associated code is not required to enter the complete device identifier of the detection module 100 and / or the infusion module 102. Different code mappings correspond to different signal strength thresholds RSSI T100 and / or RSSI T102 When the patient enters a code in program module 101, the signal strength threshold RSSI corresponding to the code in the signal strength threshold list profile is called T100 and / or RSSI T102, and further corresponds to the program module 101 identifying the different maximum distances of the patient's own detection module 100 and / or infusion module 102. When the patient operates the program module 101 to approach the detection module 100 and / or infusion module 102, after entering the maximum distance corresponding to this code, the program module 101 can establish a wireless communication connection with the detection module 100 and / or infusion module 102.

[0148] In some embodiments of the present invention, the signal strength threshold RSSI T100 and / or RSSI T102 The associated code can be a character, such as any Arabic numerals from 0 to 9, Greek numerals, or any letters from AZ, or any punctuation marks, without limitation. In an exemplary description, the Arabic numeral 5 represents a signal strength threshold RSSI. T5 The maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 corresponding to the signal strength threshold is 0.5 m. The Arabic numeral 3 represents another signal strength threshold RSSI. T3 The maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 corresponding to the signal strength threshold is 0.3 m. The letter A represents another signal strength threshold RSSI. TA The signal strength threshold corresponds to a maximum distance of 0.05 m for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102. The above characters and their corresponding maximum distances are only for exemplary description.

[0149] In some other embodiments of the present invention, the signal strength threshold RSSI T100 and / or RSSI T102 The associated code can be at least two characters, and can be composed of any Arabic numerals, Greek numerals, letters or punctuation marks, or a combination thereof, without limitation. In an exemplary description, the Arabic numeral 25 represents a signal strength threshold RSSI. T25 The maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 corresponding to the signal strength threshold is 0.25 m. The Arabic numeral 21 represents another signal strength threshold RSSI. T21 The maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 corresponding to the signal strength threshold is 0.21 m. The letter 1A represents another signal strength threshold RSSI. T1A The maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 corresponding to the signal strength threshold is 0.05 m.

[0150] In some embodiments of the present invention, the signal strength threshold RSSI T100 and / or RSSI T102 The associated code can be a symbol at any position of the device identifier, and can be either a continuous symbol code or an intermittent or jumping symbol code, which is not limited here. In an exemplary description, the code 1**2******** represents a signal strength threshold RSSI T12 , where "*" represents the device identifier code, i.e. the signal strength threshold RSSI T12 The corresponding code is located in the first and fourth digits of the device identifier. The patient only needs to enter "12" in the interactive interface of the program module 101, and the program module 101 will retrieve the signal strength threshold RSSI corresponding to the code "12". T12 .

[0151] In some other embodiments of the present invention, the signal strength threshold RSSI T100 and / or RSSI T102 The associated code is printed separately on the detection module 100 and / or the infusion module 102 or on the packaging.

[0152] After being powered on, the detection module 100 and / or the infusion module 102 transmit broadcast signals at normal power, referred to herein as the first power. In some prior arts, in order to facilitate the patient to establish a wireless communication connection, the first power is usually set relatively large to ensure the effective distance of the broadcast signal for search and identification by the program module 101. For the detection module 100 and / or the infusion module 102, transmitting the broadcast signal at the first power for a long time consumes too much power, which affects the service life of the detection module 100 and / or the infusion module 102.

[0153] Reference Fig.11d In some embodiments of the present invention, in order to save power consumption of the detection module 100 and / or the infusion module 102 and extend the service life, the detection module 100 and / or the infusion module 102 can reduce the transmission power of the broadcast signal during the broadcast signal transmission after power-on, and send the broadcast signal at a second power, which is less than the first power, for example, the second power is one-half or one-third of the first power. Under this premise, if the preset signal strength threshold RSSI is maintained T100 and / or RSSI T102 The program module 101 just searches for the broadcast signal strength to reach the preset signal strength threshold RSSI T100 and / or RSSI T102When the program module 101 is connected to the detection module 100 and / or the infusion module 102, the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 will become smaller. For example, when the broadcast signal is sent at the first power, the maximum distance for the program module 101 to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 is 0.5 m. When the broadcast signal is sent at the second power, if the preset signal strength threshold RSSI is maintained, T100 and / or RSSI T102 The maximum distance for establishing a wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102 may be reduced to 0.3m or 0.1m, so the patient needs to operate the program module 101 closer to the detection module 100 and / or the infusion module 102. After the program module 101 establishes a wireless communication connection with the detection module 100 and / or the infusion module 102, the detection module 100 and / or the infusion module 102 will increase the signal transmission power and maintain the long-distance wireless communication connection with the program module 101 at the third power. At this time, the effective communication distance between the program module 101 and the detection module 100 and / or the infusion module 102 is 0-10m, which is convenient for the daily use of the patient.

[0154] In the above embodiments, the communication distance values ​​are only described as examples, and different communication distance values ​​may be applicable to different products and solutions.

[0155] The detection module 100 and / or the infusion module 102 transmit broadcast signals at the first power after being powered on. During the period when the patient operates the program module to establish a wireless communication connection with the detection module 100 and / or the infusion module 102, due to improper operation or interference from other things, the program module 101 cannot establish a wireless communication connection with the detection module 100 and / or the infusion module 102 in time, which increases the power consumption of the detection module 100 and / or the infusion module 102 and reduces the service life of the detection module 100 and / or the infusion module 102.

[0156] For the above questions, refer to Fig.11e In some embodiments of the present invention, a time threshold is set in the detection module 100 and / or the infusion module 102, and a broadcast signal is sent with a first parameter after power is turned on, and timing is started. If the program module 101 does not establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the detection module 100 and / or the infusion module 102 will reduce the broadcast signal sending parameter and send the broadcast signal with a second parameter. In the embodiment of the present invention, the "parameter" may correspond to power or time interval.

[0157] When the "parameter" corresponds to power, as mentioned above, the second power is less than the first power, for example, the second power is half or one third of the first power. At this time, the patient needs to operate the program module 101 closer to the detection module 100 and / or the infusion module 102 to establish a wireless communication connection.

[0158] In some embodiments of the present invention, the preset time threshold for the detection module 100 and / or the infusion module 102 to send the broadcast signal at the first power after power-on is set by the manufacturer or the patient, and can be set to 0-600 seconds. Preferably, the above time threshold is set to 0-60 seconds. The above values ​​are only for exemplary description.

[0159] In other embodiments of the present invention, when the "parameter" corresponds to the time interval, if the program module 101 does not establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the power of the detection module 100 and / or the infusion module 102 to send the broadcast signal remains unchanged, but the sending time interval of the broadcast signal is adjusted. For example, within the preset time threshold, the first time interval between two adjacent broadcast signals is 0.01-10 seconds, and after exceeding the preset time threshold, the second time interval between two adjacent broadcast signals is 1-60 seconds. Preferably, after exceeding the preset time threshold, the sending time interval of the broadcast signal is increased, for example, before and after the preset time threshold, the sending time interval of two adjacent broadcast signals is increased from 0.1 seconds to 10 seconds. After increasing the sending time interval of the broadcast signal, the number of times the broadcast signal is sent per unit time is reduced, and the power consumption of the detection module 100 and / or the infusion module 102 can also be reduced, and the service life of the detection module 100 and / or the infusion module 102 can be extended. The longer the broadcast signal sending time interval is, the more power consumption is saved, but the longer the patient has to wait when operating to establish a wireless communication connection. Selecting an appropriate broadcast signal sending time interval can not only reduce power consumption but also satisfy the patient's usage experience.

[0160] In some embodiments of the present invention, in order to further reduce the power consumption of the detection module 100 and / or the infusion module 102, the transmission power of the broadcast signal may be reduced while increasing the transmission time interval of the broadcast signal.

[0161] In some embodiments of the present invention, if the patient is unable to establish a wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102 in a timely manner, the patient's own position may change when the patient performs subsequent operations to establish a wireless communication connection. The patient's own detection module 100 and / or infusion module 102 may be close to the detection modules 100 and / or infusion modules 102 of other patients, thereby increasing the risk of establishing an erroneous wireless communication connection, which is not conducive to the patient's operation to establish a wireless communication connection.

[0162] For the above questions, refer to Fig.11f In some embodiments of the present invention, a time threshold can be set in the detection module 100 and / or the infusion module 102, and the timing starts after power is turned on. If the program module 101 fails to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the blood glucose management system adds a mode of establishing a wireless communication connection by inputting a device identifier of the detection module 100 and / or the infusion module 102 in the program module 101. At this time, if the patient continues to operate to establish a wireless communication connection, he can continue to operate the program module 101 to search for broadcast signals, or input the device identifier of the detection module 100 and / or the infusion module 102 in the interactive interface of the program module 101, which reduces the possibility that the program module 101 connects to the wrong detection module 100 and / or infusion module 102.

[0163] In other embodiments of the present invention, a time threshold may also be set in the program module 101. After the patient powers on the detection module 100 and / or the infusion module 102, the timing starts when the operation is performed to establish a wireless communication connection. If the program module 101 fails to establish a wireless communication connection with the detection module 100 and / or the infusion module 102 within the preset time threshold, the patient may enter the device identifier of the detection module 100 and / or the infusion module 102 in the program module 101 to establish a wireless communication connection. At this time, if the patient continues to operate to establish a wireless communication connection, the patient may continue to operate the program module 101 to search for broadcast signals, or may enter the device identifier of the detection module 100 and / or the infusion module 102 in the interactive interface of the program module 101. This also reduces the possibility that the program module 101 connects to the wrong detection module 100 and / or infusion module 102.

[0164] In some embodiments of the present invention, the preset time threshold of the device identifier is set by the manufacturer or the patient, and can be set to 0-600 seconds. Preferably, the time threshold is set to 0-60 seconds. The above values ​​are only for exemplary description.

[0165] In some embodiments of the present invention, in some cases, when the patient operates the program module 101 to search for broadcast signals, the patient may identify that the signal strength of multiple broadcast signals is not less than the preset signal strength threshold RSSI. T100 and / or RSSI T102 In this case, the program module 101 will not be able to select a broadcast signal to establish a wireless communication connection, and will promptly remind the patient that there are multiple connectable broadcast signals around the patient, and that the operation location needs to be changed, or the wireless communication connection needs to be re-established, until the program module 101 recognizes that the signal strength of only one broadcast signal is not less than the preset signal strength threshold RSSI T100 and / or RSSI T102, or prompt the patient to input the device identifier of the detection module 100 and / or the infusion module 102, so that the program module 101 establishes a wireless communication connection with the patient's own detection module 100 and / or the infusion module 102.

[0166] In some embodiments of the present invention, in order to avoid the patient from waiting for a long time during the operation of establishing a wireless communication connection, the program module 101 starts timing when it starts searching and identifying the broadcast signal. For example, within 5 seconds after the program module 101 starts searching and identifying the broadcast signal, if the program module 101 does not identify a broadcast signal with a signal strength not less than a preset signal strength threshold, or identifies multiple broadcast signals with a signal strength not less than the preset signal strength threshold, the program module 101 will prompt the patient to re-operate to establish a wireless communication connection, or change the operation location. Within the next 20 seconds, if the program module 101 still does not identify a broadcast signal with a signal strength not less than the preset signal strength threshold, or still identifies multiple broadcast signals with a signal strength not less than the preset signal strength threshold, the program module 101 will prompt the patient to enter the device identification code of the detection module 100 and / or the infusion module 102 to establish a wireless communication connection. The above time values ​​are only for exemplary description.

[0167] In some embodiments of the present invention, it is considered that the program module 101 at the signal receiving end may have differences in recognition of broadcast signals of the same signal strength due to differences in its individual states. For example, after the program module 101 leaves the factory, as the use time goes by, its hardware gradually ages, and the recognition sensitivity of the signal strength gradually decreases. The program module 101 is generally a long-term reusable device. The program module 101 may change its recognition of the absolute strength of the broadcast signal during use. When the patient is operating to establish a wireless communication connection, the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 may also change, which may cause inconvenience to the patient's operating habits. Therefore, a signal correction coefficient can be set in the program module 101, and the broadcast signal strength searched by the program module 101 is finally determined by the arithmetic correction result of the broadcast signal strength recognized by the program module 101 and the signal correction coefficient, and the broadcast signal strength is finally determined according to the corrected broadcast signal strength and the preset signal strength threshold RSSI. T100 and / or RSSI T102 The modified broadcast signal strength can ensure that when the patient operates to establish a wireless communication connection, the maximum distance between the program module 101 and the detection module 100 and / or the infusion module 102 does not change significantly, for example, the range of change is between -0.05m and 0.05m, which can minimize the impact on the patient's operating habits.

[0168] In some embodiments of the present invention, the signal correction coefficient can be input into the program module 101 by the patient, or the signal correction coefficient can be stored in the program module 101. As the program module 101 is used for a longer time, the signal correction coefficient can be adjusted over time.

[0169] In some embodiments of the present invention, the correction arithmetic of the broadcast signal strength and the signal correction coefficient is multiplication or addition, or other algorithms.

[0170] In some embodiments of the present invention, in order to further ensure the reliability of the wireless communication connection between the program module 101 and the detection module 100 and / or the infusion module 102, the patient's confirmation instruction is required before the program module 101 and the detection module 100 and / or the infusion module 102 establish a wireless communication connection.

[0171] In summary, the present invention discloses an energy-saving blood glucose management system for establishing a wireless communication connection based on signal strength. A signal strength threshold and a time threshold are preset in the blood glucose management system. Timing is performed during the patient's operation to establish a wireless communication connection. The program module searches for nearby broadcast signals and identifies the signal strength of the broadcast signals. If a broadcast with an intensity not less than the preset signal strength threshold is found within the time threshold, the program module can establish a wireless communication connection with the detection module and / or infusion module that sends the broadcast signal without inputting the device identifier of the detection module and / or infusion module. Otherwise, the detection module and / or infusion module reduces the broadcast signal sending parameters, thereby ensuring the reliability of the program module in establishing a wireless communication connection with the patient's own detection module and / or infusion module, while reducing the power consumption of the detection module and / or infusion module.

[0172] Although some specific embodiments of the present invention have been described in detail by way of example, it will be appreciated by those skilled in the art that the above examples are for illustration only and are not intended to limit the scope of the present invention. It will be appreciated by those skilled in the art that the above embodiments may be modified without departing from the scope and spirit of the present invention. The scope of the present invention is defined by the appended claims.

Claims

1. A blood sugar management system, characterized in that: include: An on-body functional module, which is attached to the patient's skin surface and sends a broadcast signal to the outside world with a first parameter after being powered on; A program module, the program module is used to search for the nearby broadcast signal and identify the signal strength of the broadcast signal, the signal strength of the broadcast signal maps the distance between the program module and the on-body functional module; Among them, a time threshold and a signal strength threshold are preset in the blood glucose management system, and timing is performed during the patient's operation to establish a wireless communication connection. The program module compares the broadcast signal strength and the preset signal strength threshold. If a broadcast signal with a signal strength not less than the preset signal strength threshold is searched within the preset time threshold, the program module establishes a wireless communication connection with the on-body functional module that sends the broadcast signal. Otherwise, the on-body functional module sends the broadcast signal with a second parameter.

2. The blood sugar management system according to claim 1, characterized in that: The on-body functional module includes a detection module and / or an infusion module. The detection module is used to continuously detect the patient's current blood sugar value, and the infusion module is used to infuse currently required drugs into the patient's body.

3. The blood sugar management system according to claim 1, characterized in that: The first parameter corresponds to a first power, the second parameter corresponds to a second power, and the second power is less than the first power.

4. The blood sugar management system according to claim 3, characterized in that: When the on-body function module sends a signal with the first power, when the strength of the searched broadcast signal is not less than the preset signal strength threshold, the distance between the program module and the on-body function module is 0-0.5m.

5. The blood sugar management system according to claim 3, characterized in that: When the on-body function module sends a signal with the second power, when the searched broadcast signal strength is not less than the preset signal strength threshold, the distance between the program module and the on-body function module is 0-0.1m.

6. The blood sugar management system according to claim 3, characterized in that: The second power is one half or one third of the first power.

7. The blood sugar management system according to claim 1, characterized in that: The first parameter corresponds to a first time interval, the second parameter corresponds to a second time interval, and the first time interval is smaller than the second time interval.

8. The blood sugar management system according to claim 7, characterized in that: The first time interval is 0.01-10 seconds, and the second time interval is 1-60 seconds.

9. The blood sugar management system according to claim 1, characterized in that: The time threshold is 0-600 seconds.

10. The blood sugar management system according to claim 1, characterized in that: It also includes codes corresponding to the preset signal strength threshold, each of the codes corresponds to a different preset signal strength threshold, and the preset signal strength threshold can be set by inputting the codes in the program module.

11. The blood sugar management system according to claim 10, characterized in that: The code is associated with a device identifier of the on body function device.

12. The blood glucose management system according to claim 1, characterized in that: The preset time threshold is set in the on-body function module or the program module.

13. The blood glucose management system according to claim 1, characterized in that: The preset signal strength threshold is set in the program module.

14. The blood sugar management system according to claim 1, characterized in that: The preset signal strength threshold is set in the on-body function module, and the broadcast signal includes information associated with the preset signal strength threshold.

15. The blood glucose management system according to claim 1, characterized in that: When there is only one broadcast signal whose signal strength is not less than the preset signal strength threshold, the program module establishes a wireless communication connection with the on-body functional module that sends the broadcast signal; when there is more than one broadcast signal whose signal strength is not less than the preset signal strength threshold, the program module does not establish a wireless communication connection with the on-body functional module that sends the broadcast signal.

16. The blood sugar management system according to claim 15, characterized in that: When the number of broadcast signals whose signal strength is not less than the preset signal strength threshold value found out exceeds one, the blood glucose management system prompts the patient to change the operation location or input the device identifier of the on-body functional module.

17. The blood glucose management system according to claim 1, characterized in that: The program module further includes a signal correction coefficient, which is associated with a state of the program module. Before the program module compares the broadcast signal strength with the preset signal strength threshold, the broadcast signal strength is corrected based on the signal correction coefficient.

18. The blood glucose management system according to claim 1, characterized in that: Before the on-body function module and the program module establish a wireless communication connection, the patient's confirmation is required.

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