Device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension

Abstract

The invention discloses a device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, and relates to the technical field of medical instrument testing, the device comprises an eyeball environment simulation part and a suture cornea loading part, the suture cornea loading part comprises a scraping assembly and a transmission assembly, the eyeball environment simulation part comprises an intraocular pressure bubbling instrument, a hydraulic pipe, a T-shaped pipe and a tear pipe, the tear pipe is communicated with the scraping assembly, an opening in the lower end of one side of the T-shaped pipe is connected with the intraocular pressure bubbling instrument through the hydraulic pipe, and an opening in the lower end of the other side of the T-shaped pipe is provided with a hydraulic sensor. According to the device and method for simulating eyelid scraping, intraocular pressure loading and suture tension monitoring, the uniformity of cornea suture is achieved, secondary cornea damage caused by uneven suture is reduced, the risk of postoperative complications is reduced, and an experimental basis is provided for research and development of cornea substitutes.

Description

Technical Field

[0001] The invention relates to the technical field of medical instrument testing, and in particular to a device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension. Background Art

[0002] Corneal transplant surgery is an important means to treat corneal diseases and improve vision. During the operation, the quality of corneal suture directly affects postoperative recovery and visual effect. However, existing corneal suturing technology has significant limitations. First, monitoring the suture tension after corneal suture has always been an unresolved technical problem. Corneal suture tension has a significant effect on the deformation and stress of corneal tissue, but there is currently no effective means to monitor the corneal suture tension in real time, which limits the control of suture quality and the evaluation of postoperative recovery.

[0003] In clinical practice, corneal sutures mainly rely on the doctor's experience and feel to determine the suture tension, lacking objective quantitative standards and accurate monitoring methods. This subjective judgment method has certain limitations and risks. Studies have shown that uneven, shallow or deep sutures may cause secondary damage to the cornea and produce a large stress concentration phenomenon at the suture interface. These factors are the direct cause of corneal suture failure. Therefore, there is an urgent need for a test device that can provide standardized and accurate monitoring of corneal suture tension in clinical practice.

[0004] Corneal suturing is a complex and delicate surgical procedure that requires not only the surgeon to have superb skills, but also an in-depth understanding of the physical properties and mechanical environment of the cornea. In the actual physical environment, corneal suturing is affected by many factors, including eyelid scraping, changes in intraocular pressure, and the tension of the suture. These factors act together on the cornea, affecting the distribution of its stress and strain fields. Eyelid scraping can cause additional mechanical pressure on the corneal surface. If this pressure is too large, it may cause further damage to the sutured cornea or affect the stability of the suture. As an important corneal environmental factor, intraocular pressure can also produce shear force on the corneal suture. The tension of the suture is the force directly acting on the cornea during the suturing process. It needs to be just right, neither too loose to fix the wound, nor too tight to compress the corneal tissue and affect the subsequent process. In order to evaluate the effect of corneal suturing, it is crucial to understand this mechanical information.

[0005] Despite this, there is currently a lack of a test device that can simultaneously simulate eyelid scraping and intraocular pressure loading to evaluate the biomechanical response and suturing effect of the cornea under the influence of these factors. This is a major technical challenge for the development and evaluation of corneal substitutes. Existing studies mostly rely on animal models or cadaver eyes. Although these models provide certain mechanical information, they are still different from the physiological environment of living bodies. Therefore, the development of a system that can simulate eyelid scraping and intraocular pressure loading and monitor corneal suture tension is of great significance for improving corneal suturing technology, developing new corneal substitutes, and evaluating surgical effects. In summary, the existing corneal suturing technology and research methods have the following problems:

[0006] Difficulty in accurately simulating corneal eyelid scraping and intraocular pressure changes: The biomechanical properties of the cornea are extremely complex, including its anisotropy, heterogeneity, and dynamic changes related to intraocular pressure, eyelid movement, etc. Existing simulation methods are often unable to fully reproduce this more complex corneal service environment, resulting in the inability to accurately simulate the mechanical response of the cornea under actual physiological conditions. For example, although the existing in vitro corneal expansion test can maintain the integrity of the corneal tissue structure, it is unable to accurately simulate the mechanical behavior of the cornea in the actual intraocular environment due to its simplified assumptions about the spherical structure and homogeneity of the cornea, and the inability to achieve eyelid scraping and load intraocular pressure.

[0007] 2) Lack of quantitative loading method for corneal suture: In corneal transplant surgery, the uniformity and accuracy of suture are crucial to the success of the operation. However, the current clinical practice mainly relies on the doctor's experience and feel to determine the suture tension, lacking objective quantitative standards and precise monitoring methods. This subjective judgment method has certain limitations and risks, which may lead to secondary damage to the cornea or suture failure. Monitoring the tension after corneal suture is the key to ensuring the success of the operation and preventing complications. However, there is currently a lack of effective technical means to monitor and quantify the corneal suture tension in real time, which limits the accurate evaluation of surgical effects and postoperative management.

[0008] 3) Existing measurement methods cannot evaluate the suturing effect: The recovery process after corneal transplantation is complex, involving the interaction of multiple biomechanical factors, namely corneal eyelid scraping, intraocular pressure changes, and suture tension. The lack of accurate evaluation tools and methods makes it difficult for doctors to effectively monitor and intervene in the postoperative recovery process, and it is also difficult for corneal substitute researchers to directly evaluate the biomechanical response of the research subjects under actual physiological conditions. In order to solve these problems, the present invention proposes a corneal suture physical environment simulation and feedback test system, which aims to provide doctors and scientific researchers with a standardized and repeatable testing device by simulating the real corneal suture environment and loading conditions. Through this device, suture tension can be accurately monitored, eyelid scraping, intraocular pressure control and other corneal service environments can be simulated, providing guidance value for clinical medicine, and providing strong technical support for the performance evaluation of the cornea and its substitutes. Summary of the invention

[0009] The purpose of the present invention is to provide a device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, so as to solve the problems in existing corneal suturing technology such as lack of standardized and accurate monitoring means, difficulty in simulating the complex service environment of the cornea, and lack of an effective testing platform or system to evaluate the performance of corneal substitutes.

[0010] To achieve the above-mentioned objectives, the present invention provides a device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, comprising an eyeball environment simulation component and a cornea suture loading component, the cornea suture loading component comprising a scraping assembly and a transmission assembly, the eyeball environment simulation component comprising an intraocular pressure bubbler, a hydraulic tube, a T-tube and a tear duct, the tear duct is connected to the scraping assembly, the lower end opening on one side of the T-tube is connected to the intraocular pressure bubbler through the hydraulic tube, and the lower end opening on the other side of the T-tube is provided with a hydraulic sensor.

[0011] Preferably, the intraocular pressure bubble instrument comprises a base, a curved cover is arranged on the base, a groove 1 and a groove 2 are respectively provided on the outer side of the curved cover and the inner side of the base, and a limit rod is arranged in the groove 2 and the groove 1;

[0012] A cornea model is arranged on the base, the cornea model is pressed by the curved cover and is screwed and fixed on the base by a screw cap, and the base and the screw cap are connected by threads.

[0013] Preferably, the scraping assembly comprises a rotary motor, the output end of the rotary motor is fixedly connected to the upper part of the connecting rod, the lower end of the connecting rod is connected to a scraping pressure head, a scraping head with an arc-shaped structure is fixedly arranged below the scraping pressure head, and the scraping head is adapted to the curvature of the corneal model;

[0014] The connecting rod is configured as a hollow structure, a reserved hole is provided on the scraping head, and the tear duct passes through the connecting rod and the reserved hole and is fixed above the cornea model.

[0015] Preferably, the transmission assembly comprises two racks arranged on both sides of the intraocular pressure bubbler, a moving block is arranged above the two racks, a gear is arranged inside the moving block, the gear is meshed with the rack, the center of the gear is fixedly connected to a knob, and the knob extends to the outside of the moving block;

[0016] A support rod is arranged above the moving block, a sleeve is arranged on the support rod, a support member is arranged on the sleeve, a mechanical sensor is arranged on the support member, induction rings are arranged on both sides of the mechanical sensors, and sutures are connected to the induction rings on both sides.

[0017] Preferably, the T-shaped tube is fixed on the iron frame by a clamp, and the lower end opening position of the T-shaped tube is the same as the height of the reserved hole.

[0018] Preferably, the interior of the T-shaped tube is filled with liquid, and the hydraulic pressure provided is changed by changing the height of the internal liquid, and the hydraulic pressure is set to 0-10 kPa.

[0019] Preferably, a through opening is provided on the base, a hydraulic cavity is provided in the base, and the hydraulic pipe passes through the through opening and is connected with the hydraulic cavity.

[0020] A method for using a device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension comprises the following steps:

[0021] S1. Equipment preparation: Ensure that all components are intact, assemble the components correctly, calibrate the hydraulic sensor and mechanical sensor, connect the data acquisition system, and start the data acquisition system to preheat to a stable working state;

[0022] S2. Corneal operating environment simulation: install the corneal model, adjust the eyeball environment simulation components, simulate the tear environment, and monitor the environmental parameters;

[0023] S3, Suturing cornea loading: setting suturing parameters, simulating eyelid movement, applying suturing force, and monitoring suturing force.

[0024] Preferably, the specific steps of S2 are as follows:

[0025] S21. Installing the corneal model: fixing the corneal model to be tested on the curved cover of the intraocular pressure bubbler, and adjusting the position until the intraocular pressure bubbler and the center of the corneal model are on the same horizontal line, so as to simulate the real eyeball structure;

[0026] S22. Adjust the eyeball environment simulation component: inject liquid into the hydraulic chamber of the intraocular pressure bubbler through the T-tube, and adjust the hydraulic pressure to the required intraocular pressure level;

[0027] S23, simulated tear environment: dripping simulated tears in the form of water drops continuously onto the bulging cornea model through the tear duct to form a uniform tear film environment;

[0028] S24, monitoring environmental parameters: monitoring intraocular pressure levels using hydraulic sensors;

[0029] S25. Adjust corneal curvature: As needed, adjust the curved cover on the outside of the intraocular pressure bubbler to adapt to corneal models with different curvatures so that the cornea is not affected by the wrinkles caused by rotating the cover.

[0030] Preferably, the specific steps of S3 are as follows:

[0031] S31. According to the experimental purpose, the rotation frequency and amplitude of the rotating motor are set, and the height of the scraping head is adjusted to change the scraping force and frequency provided by the scraping head;

[0032] S32, scraping the corneal model back and forth with the scraping head to simulate the movement of the eyelids when blinking, and applying suture tension to the corneal model through the transmission component and the mechanical sensor, and using the suture to transfer the force on the cornea to simulate the actual suturing process;

[0033] S33. Monitor the data output by the mechanical sensor in real time, monitor the suture tension and keep it within a predetermined range, and use a camera to record the corneal morphology in real time, obtain the corneal surface coordinates through calculation, and finally determine the configuration.

[0034] Therefore, the present invention adopts the above-mentioned device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, which has the following beneficial effects:

[0035] (1) Quantitative simulation environment: The present invention realizes standardized simulation of the corneal working environment. By precisely controlling the intraocular pressure and tear environment, the present invention provides a quantitative eyeball simulation environment that can be used to perform corresponding tests on corneal materials, and can be used to evaluate the corneal suturing effect and provide corresponding optimization suggestions, thereby improving the repeatability and reliability of the experiment.

[0036] (2) Precise suture tension monitoring: Precise suture tension monitoring technology is an innovative medical monitoring method. The present invention combines mechanical sensors and precision transmission devices to achieve accurate measurement and monitoring of the size and distribution of suture tension, simulating real surgical conditions. Precise suture tension plays a decisive role in wound healing and vision recovery. Therefore, the system helps to study the impact of suture parameters on corneal healing.

[0037] (3) Providing an effective feedback testing platform: The present invention provides an effective testing platform for the research and development of corneal substitutes. The sensors and data acquisition system equipped in the present invention can monitor the intraocular pressure and suture tension in real time, and can obtain the configuration changes of the cornea before and after the test process through camera recording and other means, thereby providing instant feedback to the operator, thereby accelerating the evaluation and optimization process of new corneal-related products and shortening the time from laboratory to clinic.

[0038] (4) Obtaining corneal material properties: Based on a simulated corneal usage environment, the present invention designs a scraping head to simulate the eyelid, and designs a channel in the scraping head to allow capillaries that transmit tear fluid to pass through, thereby ensuring that the cornea remains moist during the scraping process. The cornea can be scraped for a long time at a specific frequency to obtain the material property evolution of the tested corneal material under long-term usage. The fatigue performance of the corneal model can be tested by scraping action, and its service life can be predicted.

[0039] (5) Reduce animal experiment costs: By providing a test platform that simulates the real eyeball environment, the present invention uses a simplified experimental operation process to obtain test feedback information that cannot be obtained from animal experiments in corneal substitute research, reducing dependence on animal experiments, thereby reducing the economic and time costs of related research. It is helpful to deeply analyze the mechanical properties of corneal sutures and the causes of postoperative complications. It is helpful to promote scientific research in the field of corneal sutures and corneal substitutes, and promote the development of new technologies and methods.

[0040] The technical solution of the present invention is further described in detail below through the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] Figure 1 It is a partial structural schematic diagram of an embodiment of a device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension of the present invention;

[0042] Figure 2 A schematic diagram of the structure of a scraping assembly of the device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension of the present invention;

[0043] Figure 3 A partially enlarged schematic diagram of suture loading of the device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension of the present invention;

[0044] Figure 4 A schematic diagram of the structure of an intraocular pressure bubbler for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension of the device and method of the present invention;

[0045] Figure 5A schematic diagram of the exploded structure of the intraocular pressure bubbler of the device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension of the present invention;

[0046] Figure numerals: 1. intraocular pressure bubbler; 101. through port; 2. hydraulic tube; 3. T-tube; 31. clamp; 4. iron frame; 5. hydraulic sensor; 61. rack; 62. moving block; 63. knob; 64. support rod; 65. sleeve; 66. support member; 7. suture; 8. corneal model; 9. mechanical sensor; 10. rotating motor; 11. connecting rod; 12. scraping pressure head; 121. scraping head; 13. tear duct; 14. screw cover; 15. curved cover; 151. groove one; 16. limit rod; 17. base; 171. groove two. DETAILED DESCRIPTION

[0047] The technical solution of the present invention is further described below through the accompanying drawings and embodiments.

[0048] Unless otherwise defined, the technical terms or scientific terms used in the present invention should be understood by people with ordinary skills in the field to which the present invention belongs. The words "first", "second" and similar words used in the present invention do not indicate any order, quantity or importance, but are only used to distinguish different components. "Include" or "comprise" and similar words mean that the elements or objects appearing before the word include the elements or objects listed after the word and their equivalents, without excluding other elements or objects. "Connect" or "connected" and similar words are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "Up", "down", "left", "right" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0049] Example

[0050] See also Figure 1-5 The present invention provides a device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, including an eyeball environment simulation component and a corneal suture loading component, the corneal suture loading component includes a scraping component and a transmission component, the eyeball environment simulation component includes an intraocular pressure bubbler 1, a hydraulic tube 2, a T-tube 3 and a tear duct 13, the tear duct 13 is connected to the scraping component, the lower end opening on one side of the T-tube 3 is connected to the intraocular pressure bubbler 1 through the hydraulic tube 2, and the air tightness needs to be tested before the test starts to prevent liquid leakage. The lower end opening on the other side of the T-tube 3 is provided with a hydraulic sensor 5, which is used to measure and display the hydraulic pressure value, and the measured hydraulic pressure value is displayed through an external LCD digital display screen with an accuracy of 0.01kPa.

[0051] The T-tube 3 is fixed on the iron stand 4 by a clamp 31. The clamp 31 is a double clamp connected to each other, one clamp is clamped on the iron stand 4, and the other clamp is clamped on the T-tube 3. By adjusting the height of the clamp on the iron stand 4, the T-tube 3 is adjusted to an appropriate height, so that the lower end opening position of the T-tube 3 is the same as the height of the reserved hole, so that the pressure applied to the corneal model 8 matches the hydraulic pressure value displayed by the hydraulic sensor 5, thereby realizing real-time monitoring of the internal pressure of the cornea. The design of the iron stand 4 allows fine adjustment of the height and angle of the T-tube 3 to adapt to different experimental settings and test requirements.

[0052] The interior of the T-tube 3 is filled with liquid, and the hydraulic pressure provided is changed by changing the height of the internal liquid, and the hydraulic pressure is set to 0-10kPa. The liquid is a phosphate buffer. When the hydraulic pressure sensor 5 is connected to the power supply, the phosphate buffer is injected into the port 101 of the T-tube 3 as needed. The solution is used as a medium to simulate the aqueous humor environment inside the eyeball. The phosphate buffer is selected to simulate the physiological environment inside the eyeball and ensure the biocompatibility of the corneal model 8 during the test process.

[0053] The intraocular pressure bubbler 1 is made of metal material, including a base 17, on which a curved cover 15 is arranged, and groove 151 and groove 2 171 are respectively provided on the outer side of the curved cover 15 and the inner side of the base 17, and limit rods 16 are arranged in groove 2 171 and groove 1 151, and the two limit rods 16 are used to limit the plane movement of the curved cover 15 so that it can only move downward. This design ensures that when the corneal model 8 is fixed, it will not wrinkle due to the friction caused by twisting, and can maintain a smooth curved surface shape even when the internal pressure increases, which provides convenience for subsequent corneal loading tests. A corneal model 8 is arranged above the base 17, and the corneal model 8 is pressed by the curved cover 15, and is fixed to the base 17 by screwing the cover 14, and the base 17 and the cover 14 are connected by threads.

[0054] A through opening 101 is provided on the base 17, and a hydraulic cavity is provided inside the base 17. The hydraulic tube 2 passes through the through opening 101 and is connected to the hydraulic cavity, and the hydraulic tube 2 is made of nylon material. The intraocular pressure bubbler 1 is used to simulate the aqueous humor environment in the eyeball. By connecting with the hydraulic tube 2, hydraulic pressure can be applied to the inside, so that the fixed cornea can simulate the bulging state in the real eyeball. Such a design allows the deformation of the cornea to be accurately controlled in the experiment to more realistically reflect the physiological conditions during the operation. The external design is a special curved surface structure, which is used to adapt to the curvature geometry of the corneal model 8, and can prevent the corneal model 8 from being affected by the bulging effect caused by the wrinkles caused by the knob fixation.

[0055] The scraping assembly includes a rotary motor 10, which is a Xiaomi CyberGear servo micromotor. By controlling the frequency and amplitude of the rotation through a microprocessor, the movement of the scraping head 12 can be accurately controlled to simulate different eyelid movement modes. The output end of the rotary motor 10 is fixedly connected to the upper part of the connecting rod 11, and the lower end of the connecting rod 11 is connected to the scraping head 12. The scraping head 12 is used to reciprocate and scrape the corneal implant to simulate the movement of the eyelid when blinking. A scraping head 121 with an arc structure is fixedly arranged below the scraping head 12. The scraping head 121 is adapted to the curvature of the corneal model 8 to simulate the scraping action of the real eyelid on the cornea with high fidelity. The scraping head 12 and the scraping head 121 are made of rubber material. The connecting rod 11 is set as a hollow structure, and a reserved hole with a diameter of 1 mm is opened on the scraping head 121. The tear duct 13 passes through the connecting rod 11 and the reserved hole and is fixed above the corneal model 8. The tear duct 13 is made of PDMS capillaries and is used to continuously drip tears in the form of water drops onto the bulging cornea at a quantitative frequency of 5 μl / min to form a uniform tear film environment. The design of the tear duct 13 takes into account the fluidity and distribution uniformity of tears to simulate the real tear secretion and distribution process.

[0056] The morphological changes of the corneal model 8 during the scraping process can be recorded by an industrial camera. The selection of the industrial camera takes into account high resolution and high frame rate to capture the subtle changes of the corneal model 8 during the scraping process.

[0057] The transmission assembly includes two racks 61 arranged on both sides of the intraocular pressure bubbler 1, and a moving block 62 is arranged above the two racks 61. A gear is arranged inside the moving block 62. The gear and the rack 61 are meshed and connected. The center of the gear is fixedly connected to the knob 63, and the knob 63 extends to the outside of the moving block 62. A support rod 64 is arranged above the moving block 62, and a sleeve 65 is arranged on the support rod 64. A rotating knob is arranged on the sleeve 65. The tightness of the sleeve 65 is adjusted by rotating the rotating knob so that it can move up and down on the support rod 64 to change the longitudinal position. A support member 66 is arranged on the sleeve 65, and a mechanical sensor 9 is arranged on the support member 66. The mechanical sensor 9 is used to measure the size of the suture force transmitted by the connected suture 7, with an accuracy of 0.001N. Induction rings are arranged on the mechanical sensors 9 on both sides, and sutures are connected to the induction rings on both sides. The transmission assembly is used to achieve free movement in the longitudinal and lateral directions and to be fixed at any position. It is connected to the mechanical sensor 9 to achieve the loading of the corneal suture force. When in use, by rotating the knob 63, the gear is driven to move left and right on the rack 61, thereby adjusting the lateral position of the mechanical sensor 9. By changing the height of the sleeve 65, the longitudinal position of the mechanical sensor 9 is adjusted.

[0058] The method for using the device for simulating eyelid scraping and intraocular pressure loading and monitoring suture 7 tension comprises the following steps:

[0059] S1. Equipment preparation: Ensure that all components are intact, assemble the components correctly, calibrate the hydraulic sensor 5 and the mechanical sensor 9, connect the data acquisition system, and start the data acquisition system to preheat to a stable working state. The specific steps are as follows:

[0060] S11, build the bubbler, hydraulic tube 2, T-tube 3, iron frame 4, hydraulic sensor 5, transmission device, mechanical sensor 9, micromotor, connecting rod 11, scraping head 12, and tear duct 13. Connect the components, the hydraulic sensor 5, the port 101 of the bubbler and the scraping head 12 should be located at the same horizontal line, so that the corneal model 8 and the hydraulic sensor 5 display data are equal after loading the hydraulic pressure, and the scraping head 12 remains stable when applying pressure to avoid affecting the test due to uneven pressure or equipment vibration.

[0061] S12. Connect the sensor to a data acquisition system, such as a computer or other data logging device, to monitor and record data in real time during the test.

[0062] S2, corneal operating environment simulation: install the corneal model 8, adjust the eyeball environment simulation components, simulate the tear environment, and monitor the environmental parameters. The specific steps are as follows:

[0063] S21. Install the corneal model 8: fix the corneal model 8 to be tested on the curved cover 15 of the intraocular pressure bubbler 1, and adjust the position until the intraocular pressure bubbler 1 and the center of the corneal model 8 are on the same horizontal line, so as to simulate the real eyeball structure.

[0064] S22, adjusting the eyeball environment simulation component: injecting liquid into the hydraulic chamber of the intraocular pressure bubbler 1 through the T-tube 3, and adjusting the hydraulic pressure to the required intraocular pressure level.

[0065] S23, simulating tear environment: dripping simulated tears in the form of water drops continuously onto the bulging cornea model 8 through the tear tube 13 to form a uniform tear film environment.

[0066] S24. Monitoring environmental parameters: using the hydraulic sensor 5 to monitor the intraocular pressure level.

[0067] S25, adjusting corneal curvature: as needed, adjusting the curved cover 15 outside the intraocular pressure bubbler 1 to adapt to corneal models 8 with different curvatures so that the cornea is not affected by the wrinkles caused by the screwing cover 14.

[0068] S3, corneal suture loading: set suture parameters, simulate eyelid movement, apply suture force, and monitor suture force. The specific steps are as follows:

[0069] S31. According to the experimental purpose, the rotation frequency and amplitude of the rotating motor 10 are set, and the height of the scraping head 12 is adjusted to change the scraping force and frequency provided by the scraping head 12.

[0070] S32, scraping the corneal model 8 back and forth using the scraping head 12 to simulate the movement of the eyelids during blinking, and at the same time applying tension of the suture 7 to the corneal model 8 through the transmission assembly and the mechanical sensor 9, and using the suture 7 to transfer force on the cornea to simulate the application of force during the actual suturing process.

[0071] S33, monitor the data output by the mechanical sensor 9 in real time, monitor the tension of the suture 7 and make the tension of the suture 7 within a predetermined range, and use a camera to record the corneal morphology in real time, obtain the corneal surface coordinates by calculation, and finally determine the configuration.

[0072] Therefore, the present invention adopts the above-mentioned device and method for simulating eyelid scraping and intraocular pressure loading and monitoring the tension of suture 7 to achieve uniformity of corneal suturing, reduce secondary corneal damage caused by uneven suturing, reduce the risk of postoperative complications, and provide an experimental basis for the research and development of corneal substitutes.

[0073] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that they can still modify or replace the technical solution of the present invention with equivalents, and these modifications or equivalent replacements cannot cause the modified technical solution to deviate from the spirit and scope of the technical solution of the present invention.

Claims

1. A device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, characterized in that: It includes an eyeball environment simulation component and a sutured cornea loading component, the sutured cornea loading component includes a scraping assembly and a transmission assembly, the eyeball environment simulation component includes an intraocular pressure bubbler, a hydraulic tube, a T-tube and a tear duct, the tear duct is connected to the scraping assembly, the lower end opening on one side of the T-tube is connected to the intraocular pressure bubbler through the hydraulic tube, and the lower end opening on the other side of the T-tube is provided with a hydraulic sensor.

2. The device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 1, characterized in that: The intraocular pressure bubble instrument comprises a base, a curved cover is arranged on the base, a groove 1 and a groove 2 are respectively provided on the outer side of the curved cover and the inner side of the base, and a limit rod is arranged in the groove 2 and the groove 1; A cornea model is arranged on the base, the cornea model is pressed by the curved cover and is screwed and fixed on the base by a screw cap, and the base and the screw cap are connected by threads.

3. The device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 2, characterized in that: The scraping assembly includes a rotary motor, the output end of the rotary motor is fixedly connected to the upper part of the connecting rod, the lower end of the connecting rod is connected to a scraping pressure head, a scraping head with an arc structure is fixedly arranged below the scraping pressure head, and the scraping head is adapted to the curvature of the corneal model; The connecting rod is configured as a hollow structure, a reserved hole is provided on the scraping head, and the tear duct passes through the connecting rod and the reserved hole and is fixed above the cornea model.

4. The device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 3, characterized in that: The transmission assembly includes two racks arranged on both sides of the intraocular pressure bubbler, a moving block is arranged above the two racks, a gear is arranged inside the moving block, the gear is meshed with the rack, the center of the gear is fixedly connected to a knob, and the knob extends to the outside of the moving block; A support rod is arranged above the moving block, a sleeve is arranged on the support rod, a support member is arranged on the sleeve, a mechanical sensor is arranged on the support member, induction rings are arranged on both sides of the mechanical sensors, and sutures are connected to the induction rings on both sides.

5. The device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 4, characterized in that: The T-shaped tube is fixed on the iron frame by a clamp, and the lower end opening position of the T-shaped tube is at the same height as the reserved hole.

6. The device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 5, characterized in that: The interior of the T-shaped tube is filled with liquid, and the hydraulic pressure provided is changed by changing the height of the internal liquid, and the hydraulic pressure is set to 0-10 kPa.

7. The device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 6, characterized in that: A through opening is provided on the base, a hydraulic cavity is provided in the base, and the hydraulic pipe passes through the through opening and is communicated with the hydraulic cavity.

8. A method for using the device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension as described in claim 7, characterized in that: The following steps are involved: S1. Equipment preparation: Ensure that all components are intact, assemble the components correctly, calibrate the hydraulic sensor and mechanical sensor, connect the data acquisition system, and start the data acquisition system to preheat to a stable working state; S2. Corneal operating environment simulation: install the corneal model, adjust the eyeball environment simulation components, simulate the tear environment, and monitor the environmental parameters; S3, Suturing cornea loading: setting suturing parameters, simulating eyelid movement, applying suturing force, and monitoring suturing force.

9. The method of the device for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 8, characterized in that: The specific steps of S2 are as follows: S21. Installing the corneal model: fixing the corneal model to be tested on the curved cover of the intraocular pressure bubbler, and adjusting the position until the intraocular pressure bubbler and the center of the corneal model are on the same horizontal line, so as to simulate the real eyeball structure; S22. Adjust the eyeball environment simulation component: inject liquid into the hydraulic chamber of the intraocular pressure bubbler through the T-tube, and adjust the hydraulic pressure to the required intraocular pressure level; S23, simulating tear environment: dropping simulated tears in the form of water drops continuously onto the bulging cornea model through the tear duct to form a uniform tear film environment; S24, monitoring environmental parameters: monitoring intraocular pressure levels using hydraulic sensors; S25. Adjust corneal curvature: As needed, adjust the curved cover on the outside of the intraocular pressure bubbler to adapt to corneal models with different curvatures so that the cornea is not affected by the wrinkles caused by rotating the cover.

10. The method of simulating eyelid scraping and intraocular pressure loading and monitoring suture tension according to claim 9, characterized in that: The specific steps of S3 are as follows: S31. According to the experimental purpose, the rotation frequency and amplitude of the rotating motor are set, and the height of the scraping head is adjusted to change the scraping force and frequency provided by the scraping head; S32, scraping the corneal model back and forth with the scraping head to simulate the movement of the eyelids when blinking, and applying suture tension to the corneal model through the transmission component and the mechanical sensor, and using the suture to transfer the force on the cornea to simulate the actual suturing process; S33. Monitor the data output by the mechanical sensor in real time, monitor the suture tension and make it within a predetermined range, and use a camera to record the corneal morphology in real time, obtain the corneal surface coordinates through calculation, and finally determine the configuration.

Images