Characteristic chromatogram construction method, characteristic chromatogram and detection method of traditional Chinese medicine granules
The characteristic map of traditional Chinese medicine particles is constructed through liquid chromatography analysis technology, which solves the problem of difficulty in controlling the quality of traditional Chinese medicine particles in the existing technology, and realizes the quality monitoring of traditional Chinese medicine particles and guarantees the efficacy and safety of the product.
CN120121771APending Publication Date: 2025-06-10HENAN MEDICAL DEVICE INSPECTION INST +1
Patent Information
- Application Number
- CN202510267098.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-07
- Publication Date
- 2025-06-10
AI Technical Summary
Technical Problem
The prior art is difficult to effectively control the overall quality of traditional Chinese medicine particles, which makes it difficult to monitor the complexity of its components.
Method used
Through liquid chromatography analysis technology, a characteristic map of traditional Chinese medicine particles is constructed, and the characteristic map is used for quality detection and control to ensure the efficacy and safety of traditional Chinese medicine particles products.
Benefits of technology
The quality monitoring of multiple index components of traditional Chinese medicine particles has been achieved, the quality evaluation and control level has been improved, and the efficacy and safety of the product have been ensured.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN120121771A_ABST
Abstract
The invention relates to the technical field of traditional Chinese medicine detection, in particular to a characteristic spectrum construction method, a characteristic spectrum and a detection method of traditional Chinese medicine granules. The traditional Chinese medicine granules comprise protocatechuic aldehyde, hydroxysafflor yellow A, salvianolic acid B, cinnamic acid and cinnamaldehyde; the construction method comprises the following steps: taking protocatechuic aldehyde, hydroxysafflor yellow A, salvianolic acid B, cinnamic acid and cinnamaldehyde reference substances, and preparing a mixed reference substance solution; preparing a test solution from the traditional Chinese medicine granules; and respectively carrying out liquid chromatographic analysis on the mixed reference substance solution and the test solution to obtain the characteristic chromatogram of the traditional Chinese medicine granules. Wherein the liquid chromatographic analysis conditions comprise that a phosphoric acid solution is used as a mobile phase A, acetonitrile is used as a mobile phase B, and gradient elution is carried out. The problem that the quality of traditional Chinese medicine particles is difficult to control is solved.
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Citation Information
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