Radix codonopsis and radix astragali pulse-invigorating pill and preparation method thereof

Abstract

The pill comprises the following components in percentage by weight: 10-15% of a red ginseng extract, 5-10% of a ligusticum wallichii extract, 5-10% of an angelica sinensis extract, 5-10% of an astragalus membranaceus extract, 5-10% of a medlar extract, 5-10% of a liquorice extract, 5-10% of a salvia miltiorrhiza extract, 5-10% of a pericarpium citri reticulatae extract and 5-10% of a chrysanthemum extract. The pill is prepared from, by weight, 5%-10% of radix angelicae sinensis extract, 8%-12% of radix astragali seu hedysari extract, 5%-8% of fructus lycii extract, 3%-5% of radix glycyrrhizae extract, 6%-10% of radix salviae miltiorrhizae extract, 2%-5% of pericarpium citri reticulatae extract and 2%-4% of flos chrysanthemi extract, the proportion of effective components in all the extracts is optimized, and the pill activity can be enhanced, qi and blood can be regulated, and heart blood circulation can be improved. Therefore, the safety and the quality consistency of the pill are improved while the drug effect is guaranteed, the problems that the traditional Shenqi Tongmai pill is low in traditional Chinese medicinal material extraction rate, uneven in drug effect exertion and residual in harmful ingredients are solved, and the preparation method of the Shenqi Tongmai pill which is more stable in curative effect and more remarkable in drug effect is provided.

Description

Technical Field

[0001] The present invention relates to the technical field of the preparation of Shenqi Tongmai Pills, and particularly to a Shenqi Tongmai Pill and its preparation method. Background Art

[0002] As a traditional Chinese medicine pill, Shenqi Tongmai Pills are widely used in the treatment of various diseases caused by qi stagnation and blood stasis, and have achieved remarkable effects especially in improving blood circulation, regulating qi and blood, and promoting blood circulation to remove stasis. Traditional Shenqi Tongmai Pills are usually made by mixing extracts of traditional Chinese medicinal materials such as red ginseng, chuanxiong rhizome, angelica sinensis, astragalus membranaceus, and wolfberry fruit. By cooperating with each other, the medicinal effects of each component are enhanced to achieve the effects of regulating qi and blood and dispelling wind and dredging collaterals. These medicinal materials are obtained through different extraction processes, and their active ingredients can act together to effectively relieve symptoms such as chest tightness, headache, and numbness of hands and feet.

[0003] However, there are some deficiencies in the preparation process of Shenqi Tongmai Pills in the prior art. First of all, due to the inaccurate control of the extraction rate and proportion of the active ingredients of traditional Chinese medicine extracts, the exertion of the medicinal effect may be restricted to a certain extent. Especially when multiple medicinal materials are formulated together, if the extraction ratio of each medicinal material is not optimized, it may lead to insufficient medicinal effect. Secondly, the traditional extraction process and concentration process may not be able to fully extract the active ingredients in the medicinal materials, or may retain unnecessary impurities, affecting the quality and efficacy of the pills. Summary of the Invention

[0004] The present invention aims to solve at least one of the technical problems in the related art to some extent.

[0005] For this purpose, the object of the present invention is to provide a Shenqi Tongmai Pill and its preparation method, which can, through precise ratios of medicinal material extracts (such as red ginseng, chuanxiong rhizome, angelica sinensis, etc.), and by adopting advanced extraction techniques (such as steam distillation method, supercritical CO2 extraction method, etc.), increase the concentration of active ingredients in each medicinal material, while reducing unnecessary impurities. These optimization measures ensure that the medicinal effect of Shenqi Tongmai Pills is more stable, and the active ingredients play a better role, effectively solving the problems of low extraction rate and uneven medicinal effect in the prior art, and improving the quality and efficacy of the pills.

[0006] To achieve the above object, the present invention provides a Shenqi Tongmai Pill and its preparation method, which include the following components: 200 g of astragalus membranaceus, 100 g of ginseng, 150 g of ganoderma lucidum, 100 g of cordyceps sinensis, 100 g of pheretima aspergillum, 100 g of chuanxiong rhizome, 100 g of angelica sinensis, 150 g of suberect spatholobus stem, 100 g of carthamus tinctorius, 100 g of achyranthes bidentata, 100 g of persica, 100 g of paeonia lactiflora, 150 g of salvia miltiorrhiza, 100 g of cassia twig, 100 g of myrrh, 100 g of dragon's blood, 100 g of dipsacus asperoides, 100 g of taxillus chinensis.

[0007] The present invention relates to a Shenqi Tongmai Pills and its preparation method. By precisely proportioning extracts of various Chinese medicinal materials and adopting advanced extraction techniques, the extraction rate and bioavailability of the active ingredients in each medicinal material are improved. Medicinal materials such as red ginseng, chuanxiong rhizome, angelica sinensis, and astragalus membranaceus are extracted by methods such as steam distillation, ethanol extraction, and supercritical CO2 extraction, thus ensuring that the active ingredients in these medicinal materials are retained to the greatest extent during the preparation process. After the extracts are mixed in a certain proportion, they are further made into pills through optimized concentration and drying processes, ensuring the effectiveness and stability of the finished pills. At the same time, through the optimized extraction process, the residue of harmful ingredients is reduced, and the impurity pollution that may occur in traditional extraction methods is avoided. This method not only ensures the medicinal effect but also improves the safety and quality consistency of the pills. Through this innovative extraction and preparation process, the problems of low extraction rate of Chinese medicinal materials, uneven exertion of medicinal effects, and residue of harmful ingredients in traditional Shenqi Tongmai Pills are solved, and a preparation method of Shenqi Tongmai Pills with more stable curative effect and more significant medicinal effect is provided.

[0008] Specifically, the chuanxiong rhizome extract is extracted by the ethanol extraction method, and the extract content is 15% - 25% of the weight of the dry chuanxiong rhizome.

[0009] Specifically, the angelica sinensis extract is extracted by the supercritical CO2 extraction method, and the extract content is 20% - 30% of the weight of the dry angelica sinensis.

[0010] Specifically, the cassia twig extract is extracted by the water extraction method, and the extract content is 10% - 15% of the weight of the dry cassia twig.

[0011] A preparation method of Shenqi Tongmai Pills includes the following steps:

[0012] S1. According to the formula ratio, each Chinese medicinal material is crushed and dried to obtain raw material powder;

[0013] S2. The raw material powder is mixed in proportion and subjected to soaking extraction, and the extraction solution is treated by the solvent recovery method;

[0014] S3. After the extraction solution is concentrated, an appropriate amount of auxiliary materials is added to prepare a uniform paste;

[0015] S4. The paste is adjusted and kneaded at low temperature to finally make pills, and dried to the specified moisture content;

[0016] S5. Finally, the prepared Shenqi Tongmai Pills are screened, packaged, and subjected to quality inspection.

[0017] Specifically, in step S2, the soaking extraction process uses 70% ethanol as the extraction solvent, refluxes at 60°C for 2 hours, extracts 2 times, and the liquid-to-solid ratio is 10:1 each time.

[0018] Specifically, the adjuvants described in step S3 include honey and dextrin. The amount of honey used is 5% - 10% of the total mass of the extract, which is used to improve the viscosity of pill making and the taste of the finished product. The amount of dextrin used is 3% - 5%, which is used to adjust the formability and disintegration time of the pills.

[0019] Additional aspects and advantages of the present invention will be given in part in the following description, become apparent in part from the following description, or be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The above and / or additional aspects and advantages of the present invention will become apparent and be readily understood from the following description of the embodiments in conjunction with the drawings, wherein:

[0021] Figure 1 It is a graph of experimental data of Example 1 of the Shenqi Tongmai Pills and its preparation method of the present invention;

[0022] Figure 2 It is a graph of experimental data of Example 2 of the Shenqi Tongmai Pills and its preparation method of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0023] The embodiments of the present invention will be described in detail below. The examples of the embodiments are shown in the drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are intended to explain the present invention, and should not be construed as limiting the present invention. On the contrary, the embodiments of the present invention include all variations, modifications, and equivalents falling within the spirit and scope of the appended claims.

[0024] The Shenqi Tongmai Pills and its preparation method according to the embodiments of the present invention will be described below in conjunction with the drawings.

[0025] As Figure 1 shown, the Shenqi Tongmai Pills and its preparation method according to the embodiments of the present invention

[0026] include the following components: 200 g of Astragalus membranaceus, 100 g of Panax ginseng, 150 g of Ganoderma lucidum, 100 g of Cordyceps sinensis, 100 g of Pheretima aspergillum, 100 g of Ligusticum chuanxiong, 100 g of Angelica sinensis, 150 g of Spatholobus suberectus, 100 g of Carthamus tinctorius, 100 g of Achyranthes bidentata, 100 g of Prunus persica, 100 g of Paeonia lactiflora, 150 g of Salvia miltiorrhiza, 100 g of Cinnamomum cassia, 100 g of Myrrha, 100 g of Sanguis draxonis, 100 g of Dipsacus asperoides, 100 g of Taxillus chinensis.

[0027] It should be noted that in this embodiment, the Shenqi Tongmai Pills are formulated rationally to integrate multiple pharmacological mechanisms such as replenishing qi, promoting blood circulation, dredging collaterals, and removing stasis. Astragalus membranaceus and Panax ginseng are used to greatly replenish qi and enhance the blood supply to the heart and brain. Ganoderma lucidum and Cordyceps sinensis can regulate immunity and have antioxidant effects. Blood-activating and stasis-removing herbs such as Ligusticum chuanxiong, Angelica sinensis, Salvia miltiorrhiza, and Paeonia lactiflora work synergistically to dredge meridians and collaterals and soften blood vessels. Spatholobus suberectus, Achyranthes bidentata, Dipsacus asperoides, and Taxillus chinensis have the effects of tonifying the liver and kidney, strengthening bones and muscles, and dredging meridians to relieve pain. Cinnamomum cassia, Prunus persica, Myrrha, and Sanguis draxonis can warm the meridians to relieve pain and promote blood circulation to generate new blood. In particular, Sanguis draxonis plays an important role in repairing vascular endothelium. This formula comprehensively reflects the therapeutic principle of traditional Chinese medicine of "replenishing qi and promoting blood circulation, dredging collaterals and removing stasis", is applicable to the adjuvant treatment of chronic ischemia of the cardiovascular and cerebrovascular systems and diseases of meridian blockage, and has good synergistic effects and overall regulatory capabilities.

[0028] Further, as Figure 1 shown, the Ligusticum chuanxiong extract is extracted by the ethanol extraction method, and the extract content is 15% - 25% of the weight of the dried Ligusticum chuanxiong.

[0029] It should be noted that the ethanol extraction method used for the Ligusticum chuanxiong extract described in this embodiment can effectively retain volatile oils and liposoluble active ingredients such as ferulic acid. Ethanol, as a solvent with moderate polarity, can dissolve various phenolic acids and organic acids with blood-activating effects in Ligusticum chuanxiong, improving the extraction efficiency and component stability. By controlling the extraction process parameters, the extract content is stabilized at 15% - 25% of the weight of the dried Ligusticum chuanxiong, which not only ensures the full extraction of pharmacodynamic substances but also facilitates the subsequent concentration and metering control of the preparation. This extraction method has the advantages of simple operation, strong repeatability, and high component purity, which helps to improve the quality controllability of the Shenqi Tongmai Pills preparation and its adaptability to industrial production.

[0030] Further, as Figure 1 shown, the Angelica sinensis extract is extracted by the supercritical CO2 extraction method, and the extract content is 20% - 30% of the weight of the dried Angelica sinensis.

[0031] It should be noted that the supercritical CO2 extraction method used for the Angelica sinensis extract described in this embodiment utilizes the high selective solubility of carbon dioxide in the supercritical state for liposoluble active ingredients, which can efficiently extract volatile oils, coumarins, and various liposoluble substances with blood-activating and anti-inflammatory effects in Angelica sinensis, while avoiding the degradation of heat-sensitive components or the problem of residual solvents in traditional water extraction or alcohol extraction. By controlling the extraction pressure, temperature, and time parameters, the extract content is stabilized at 20% - 30% of the weight of the dried Angelica sinensis, which not only ensures the stable release of pharmacodynamic components but also enhances the uniformity and traceability of the preparation quality, providing technical support for the efficient, safe, and modern production of the Shenqi Tongmai Pills.

[0032] Further, as Figure 1As shown, the cassia twig extract is extracted by the water extraction method, and the extract content is 10% - 15% of the weight of the dried cassia twig product.

[0033] It should be noted that in this embodiment, the cassia twig extract described is extracted by the water extraction method, which can fully dissolve the rich volatile oils, water-soluble flavonoids, cinnamaldehyde and other components with the effects of relieving muscle and promoting sweating, warming the channels and promoting blood circulation. Water, as a green solvent, can effectively retain the warming and dispersing activity of cassia twig when extracted at an appropriate temperature, while reducing the impact of organic solvent residues on the safety of the finished product. By optimizing the decocting time, concentration process and drying method, the extract content is stabilized at 10% - 15% of the weight of the dried cassia twig product, which not only ensures the stability and dose controllability of the core pharmacodynamic components, but also improves the clinical application effect of Shenqi Tongmai Pills in aspects such as warming the channels and dredging collaterals and relieving muscle spasms.

[0034] The preparation method includes the following steps:

[0035] S1. According to the formula ratio, each Chinese medicinal material is pulverized and dried to obtain raw material powder;

[0036] S2. The raw material powder is mixed in proportion and subjected to soaking extraction, and the extract is treated by the solvent recovery method;

[0037] S3. After the extract is concentrated, an appropriate amount of auxiliary materials are added to prepare a uniform paste;

[0038] S4. The paste is adjusted and kneaded at low temperature and finally made into pills, and dried to the specified moisture content;

[0039] S5. Finally, the prepared Shenqi Tongmai Pills are screened, packaged and subjected to quality inspection.

[0040] It should be noted that the key to the preparation method described in this embodiment lies in the optimized extraction and concentration processes, ensuring that the active ingredients of the extract are concentrated and of high purity. The selection of auxiliary materials is also carefully designed to enable the full release of the active ingredients in the pills. Through low-temperature drying, the active substances of the drug are ensured not to be excessively degraded, improving the curative effect of Shenqi Tongmai Pills.

[0041] Furthermore, as Figure 1 shown, in the soaking extraction process described in step S2, 70% ethanol is used as the extraction solvent, reflux extraction is carried out at 60 °C for 2 hours, and extraction is carried out 2 times, with a liquid-to-solid ratio of 10:1 each time. The auxiliary materials described in step S3 include honey and dextrin. The amount of honey used is 5% - 10% of the total mass of the extract, which is used to improve the viscosity of pill making and the taste of the finished product. The amount of dextrin used is 3% - 5%, which is used to adjust the formability and disintegration time of the pills.

[0042] It should be noted that in this embodiment, the process design of reflux extraction for 2 hours at 60°C with 70% ethanol as the extraction solvent for 2 times in step S2 takes into account the dissolution efficiency of both polar and non-polar components, and can effectively extract various active ingredients in traditional Chinese medicinal materials such as flavonoids, phenolic acids, volatile oils, etc., ensuring the integrity of the extract components and the concentration stability; the liquid-solid ratio is controlled at 10:1 each time, which can not only fully dissolve the active ingredients, but also facilitate the subsequent solvent recovery and concentration treatment, being conducive to energy conservation and environmental protection; in step S3, honey and dextrin are introduced as excipients. Among them, in addition to providing appropriate viscosity, honey also has the effect of moistening the lungs and nourishing qi, helping to enhance the taste of the finished product and the patient compliance. Dextrin improves the plasticity and disintegration behavior of the powder through its rheological properties, helping to maintain the uniformity of the dosage form during the pill-making process and the drug release stability in the later stage, thereby improving the forming quality and clinical use effect of Shenqi Tongmai Pills.

[0043] Example 1:

[0044] Preparation method of Shenqi Tongmai Pills based on optimized formula and extraction process

[0045] Background:

[0046] This embodiment aims to demonstrate the preparation of Shenqi Tongmai Pills by optimizing the formula and extraction process to enhance the drug efficacy and improve the extraction rate of components. This embodiment details how to improve the concentration of active ingredients in each medicinal material and ensure the consistency of drug efficacy through precise proportioning and advanced extraction techniques.

[0047] Experimental materials:

[0048] Astragalus membranaceus, Panax ginseng, Ganoderma lucidum, Cordyceps sinensis, Pheretima aspergillum, Ligusticum chuanxiong, Angelica sinensis, Spatholobus suberectus, Carthamus tinctorius, Achyranthes bidentata, Prunus persica, Paeonia lactiflora, Salvia miltiorrhiza, Cinnamomum cassia, Myrrha, Sanguis draxonis, Dipsacus asperoides, Taxillus chinensis

[0049] Extraction solvents: water, ethanol, supercritical CO2

[0050] Experimental steps:

[0051] Crushing and drying of medicinal materials:

[0052] Crush medicinal materials such as Astragalus membranaceus, Panax ginseng, Ganoderma lucidum, etc., and perform low-temperature drying at 45°C until the water content is lower than 10%.

[0053] Extraction process:

[0054] Extract of Cinnamomum cassia: Use steam distillation method to extract the active ingredients in Cinnamomum cassia, and control the concentration of the extract at 30%-50% of the dry weight of Cinnamomum cassia.

[0055] Extract of Ligusticum chuanxiong: Adopt ethanol extraction method, and the concentration of the extract is 15%-25% of the dry weight of Ligusticum chuanxiong.

[0056] Angelica extract: Using supercritical CO2 extraction method, the concentration of the extract is 20%-30% of the weight of dry Angelica sinensis.

[0057] The extracts of other medicinal materials (such as Astragalus membranaceus, Lycium barbarum, Glycyrrhiza uralensis, etc.) are obtained by water extraction method, and the concentration range is 3%-10% of the weight of dry medicinal materials.

[0058] Concentration and mixing of extracts:

[0059] Concentrate the extracts of each medicinal material to a certain concentration (about 1 / 3 of the original solution), and then mix them precisely according to the ratio in claim 1.

[0060] Preparation of pills:

[0061] Mix the concentrated extract with excipients (such as honey, starch, etc.) to prepare a paste, and make pills with a diameter of about 0.5 cm through processes such as kneading and rolling pills. Finally, dry the prepared pills at 60°C until the water content is controlled at 3%-5%.

[0062] Quality inspection and packaging:

[0063] Conduct quality inspections such as appearance inspection, content determination, dissolution test, etc. on the prepared Shenqi Tongmai Pills, and perform packaging after meeting the standards.

[0064] Experimental results:

[0065] Analysis of the content of active ingredients:

[0066] Use HPLC analysis method to determine the content of active ingredients in each medicinal material extract, such as ginsenosides in red ginseng, ligustrazine in Ligusticum chuanxiong, Angelica polysaccharide in Angelica sinensis, etc. The experimental results show that through the optimized extraction process, the extraction rate of active ingredients in each medicinal material has increased by 20%-30% compared with the traditional process.

[0067] Pharmacodynamic evaluation:

[0068] Use animal models (such as rat blood circulation model) for pharmacodynamic evaluation. After oral administration, the hemorheological indexes of animals (such as blood viscosity, erythrocyte sedimentation rate) are significantly improved, showing that the pharmacodynamic effect is significantly better than that of traditional Shenqi Tongmai Pills.

[0069] Example 2:

[0070] Preparation of Shenqi Tongmai Pills with optimized formula and its clinical application

[0071] Background:

[0072] In this example, by optimizing the formula ratio and extraction process of Shenqi Tongmai Pills, clinical experiments are carried out to verify and evaluate the actual effects of the new preparation method in improving blood circulation, regulating qi and blood, etc.

[0073] Experimental materials:

[0074] Red ginseng, chuanxiong rhizome, angelica sinensis, astragalus membranaceus, wolfberry fruit, licorice root, salvia miltiorrhiza, tangerine peel, chrysanthemum

[0075] Extraction solvents: water, ethanol, supercritical CO2

[0076] Experimental procedures:

[0077] Selection and extraction of medicinal materials:

[0078] Select high-quality Chinese medicinal materials such as red ginseng, chuanxiong rhizome, and angelica sinensis according to the formula ratio in claim 1, and extract them using the above optimized extraction process, and control the concentration of each extract within the specified range.

[0079] Formula preparation:

[0080] Mix the extracts according to the ratio in claim 1, where the red ginseng extract is 15%, the chuanxiong rhizome extract is 10%, the angelica sinensis extract is 8%, etc., to ensure that the synergistic effect of each component is fully exerted.

[0081] Preparation and quality control of pills:

[0082] Concentrate the mixed extract to a paste, add appropriate excipients, and prepare it into uniform pills. The pills are dried at low temperature to an appropriate moisture content, and quality control such as appearance, weight, and hardness is carried out.

[0083] Clinical trials:

[0084] Select 60 patients (30 males and 30 females), and divide them into a treatment group and a control group according to the patients' conditions. The treatment group is given the newly prepared Shenqi Tongmai Pills, 2 times a day, 5 pills each time, and the control group is given the traditional Shenqi Tongmai Pills. The treatment period is 4 weeks. After the treatment, clinical evaluations are carried out, including symptom improvement scores, hemorheology tests, and improvement of clinical signs.

[0085] Experimental results:

[0086] Symptom improvement evaluation:

[0087] After 4 weeks of treatment, the improvement degree of symptoms such as chest tightness, headache, and numbness of hands and feet in the treatment group was significantly better than that in the control group, and the subjective feelings of the patients also indicated that the newly prepared Shenqi Tongmai Pills had better effects.

[0088] Hemorheology indexes:

[0089] Hemorheology tests showed that the blood viscosity and erythrocyte sedimentation rate of the patients in the treatment group were significantly lower than the baseline values, showing good effects of promoting blood circulation and removing blood stasis.

[0090] Clinical effect comparison:

[0091] After 4 weeks of treatment, the overall effective rate of the treatment group was 90%, while that of the control group was 75%. Through statistical analysis, the difference between the treatment group and the control group was significant (P<0.05), indicating that the newly prepared Shenqi Tongmai Pills had better efficacy in improving qi and blood circulation.

[0092] In summary, by precisely proportioning extracts of various Chinese medicinal herbs and adopting advanced extraction techniques, the extraction rate and bioavailability of the active ingredients in each herb were improved. Herbs such as red ginseng, chuanxiong, angelica, and astragalus were extracted by methods such as steam distillation, ethanol extraction, and supercritical CO2 extraction, thus ensuring that the active ingredients in these herbs were retained to the greatest extent during the preparation process. After the extracts were mixed in a certain proportion, they were further made into pills through optimized concentration and drying processes, ensuring the effectiveness and stability of the finished pills. At the same time, through the optimized extraction process, the residue of harmful components was reduced, and the impurity pollution that might occur in traditional extraction methods was avoided. This method not only ensured the efficacy of the medicine but also improved the safety and quality consistency of the pills. Through this innovative extraction and preparation process, the present invention effectively solved the problems of low extraction rate of Chinese medicinal herbs, uneven efficacy, and residue of harmful components in traditional Shenqi Tongmai Pills, and provided a method for preparing Shenqi Tongmai Pills with more stable efficacy and more significant medicinal effects.

[0093] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those of ordinary skill in the art can make changes, modifications, substitutions, and variations to the above embodiments within the scope of the present invention.

Claims

1. A Shenqi Tongmai Pill, characterized in that: It includes the following ingredients: 200g of Astragalus, 100g of Ginseng, 150g of Ganoderma lucidum, 100g of Cordyceps sinensis, 100g of Pheretima, 100g of Chuanxiong, 100g of Angelica sinensis, 150g of Millettia reticulata, 100g of Safflower, 100g of Niu Xi, 100g of Peach Kernel, 100g of Red Peony Root, 150g of Salvia miltiorrhiza, 100g of Cassia Twig, 100g of Myrrh, 100g of Sanguisorba officinalis, 100g of Chuanduan, and 100g of Parasitic Plant.

2. The Shenqi Tongmai Pill according to claim 1, characterized in that The chuanxiong extract is extracted by ethanol extraction, and the content of the extract is 15% to 25% of the weight of the chuanxiong dry product.

3. The Shenqi Tongmai Pill according to claim 1, characterized in that The angelica extract is extracted by supercritical CO2 extraction, and the content of the extract is 20% to 30% of the weight of the angelica dry product.

4. The Shenqi Tongmai Pill according to claim 1, characterized in that The cinnamon twig extract is extracted by water extraction, and the content of the extract is 10% to 15% of the weight of the cinnamon twig dry product.

5. A method for preparing Shenqi Tongmai Pills, according to claims 1-4, characterized in that: The following steps are involved: S1. According to the formula ratio, each Chinese medicinal material is crushed and dried to obtain raw material powder; S2. The raw powders are mixed in proportion, extracted by immersion, and the extract is treated by a solvent recovery method; S3. After the extract is concentrated, an appropriate amount of auxiliary materials is added to form a uniform paste; S4. The paste is adjusted and kneaded at low temperature to finally form pills, which are dried to a specified moisture content; S5. Finally, the prepared Shenqi Tongmai Pills are screened, packaged, and quality inspected.

6. The method for preparing Shenqi Tongmai Pills according to claim 5, characterized in that: The soaking extraction process in step S2 uses 70% ethanol as the extraction solvent, refluxes at 60° C. for 2 hours, and extracts twice, each time with a liquid-to-solid ratio of 10:

1.

7. The method for preparing Shenqi Tongmai Pills according to claim 5, characterized in that: The auxiliary materials in step S3 include honey and dextrin. The amount of honey is 5% to 10% of the total mass of the extract, which is used to improve the viscosity of the pills and the taste of the finished product. The amount of dextrin is 3% to 5%, which is used to adjust the pill forming properties and disintegration time.

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