Antibacterial sanitary towel and preparation method thereof

Abstract

The invention provides an antibacterial sanitary napkin and a preparation method thereof.The antibacterial sanitary napkin comprises a surface layer, an absorption core layer and a bottom film, the absorption core layer is located between the bottom film and the surface layer, and an antibacterial compound is added to the surface layer and / or between the surface layer and the absorption core layer; the antibacterial compound is prepared from the following raw materials: cortex cinnamomi, rhizoma cyperi, fructus cnidii, herba leonuri, fructus amomi rotundus, radix sophorae flavescentis, fructus foeniculi, rhizoma coptidis and radix angelicae sinensis. According to the antibacterial sanitary towel, through the synergistic effect of natural plant components, the antibacterial, anti-inflammatory, itching-relieving and soothing effects can be achieved, and healthier and more comfortable menstrual period nursing experience can be provided for women.

Description

Technical Field

[0001] This application belongs to the field of manufacturing feminine hygiene products, and specifically relates to an antibacterial sanitary napkin and its preparation method. Background Art

[0002] Sanitary napkins are feminine hygiene products used during menstruation, and their main materials include cotton, non-woven fabric, pulp, etc. The function of sanitary napkins is to absorb the menstrual blood flowing out of the vagina during a woman's menstruation. During a woman's menstrual period, due to endocrine effects, the body's functions change, resistance decreases, the menstrual blood often has an unpleasant odor, and it is easy to breed bacteria, which can easily infect the reproductive system, gynecological diseases, urinary tract infections, etc., and is prone to risks such as skin itching and swelling.

[0003] In currently disclosed technical materials related to sanitary napkins, plant antibacterial components are also added. For example, in the patent with the patent number CN113616844A and the patent name: A Sanitary Napkin Capable of Reducing Odor and Its Production Process, a combination of traditional Chinese medicine raw materials such as Dictamnus dasycarpus Turcz., Evodia rutaecarpa (Juss.) Benth., Taraxacum mongolicum Hand.-Mazz., Cnidium monnieri (L.) Cuss. and Aquilaria sinensis (Lour.) Spreng. is used to exert the effect of inhibiting and killing bacteria; in the patent with the patent number CN118979381A and the patent name: An Antibacterial and Disease-Preventing Non-Woven Fabric for Female Care and Its Application, a composition of Atractylodes lancea (Thunb.) DC., Borneol, Coptis chinensis Franch., Leonurus japonicus Houtt., Dry Ginger, Cnidium monnieri (L.) Cuss., and Sophora flavescens Ait. is used to regulate the meridians and inhibit bacteria, etc.

[0004] However, in the currently disclosed relevant materials, when applied to sanitary napkins during actual use, the antibacterial effect is very limited and the duration is relatively short. Summary of the Invention

[0005] To solve the above problems, this application proposes an antibacterial sanitary napkin, which includes a surface layer, an absorption core layer, and a bottom film. The absorption core layer is located between the bottom film and the surface layer, and an antibacterial composite is added between the surface layer and / or between the surface layer and the absorption core layer. The antibacterial composite includes raw materials in the following mass fractions: cinnamon, cyperus rotundus, cnidium monnieri, motherwort, cardamom, sophora flavescens, fennel, coptis chinensis, angelica sinensis.

[0006] Cnidium monnieri: It contains osthole and has broad-spectrum antibacterial and antifungal effects. It can inhibit Staphylococcus aureus, Candida albicans, etc., can prevent local infections during menstruation, reduce odors, and has the effects of drying dampness, expelling wind, killing insects, and relieving itching.

[0007] Sophora flavescens and Coptis chinensis: They contain components such as matrine and berberine, can inhibit the growth of bacteria and fungi, relieve vulvar itching, and reduce the odor of secretions.

[0008] Cinnamon contains cinnamaldehyde, which has an inhibitory effect on bacteria and fungi.

[0009] Cardamom contains components such as cineole, which also has an inhibitory effect on bacteria.

[0010] Angelica sinensis: It contains components such as ferulic acid, has antibacterial effects and can assist in anti - inflammation.

[0011] Anethole in the volatile oil of fennel has an inhibitory effect on some bacteria.

[0012] Cyperus rotundus, Leonurus japonicus, Cinnamomum cassia: By promoting local blood circulation, they can relieve abdominal pain and discomfort caused by cold uterus.

[0013] Cinnamomum cassia, Amomum kravanh, Fennel, Cyperus rotundus: By their smell, they can soothe tense emotions and indirectly relieve dysmenorrhea.

[0014] Furthermore, on the basis of the basic formula of this application, other ingredients can also be added according to consumer needs. For example: Chamomile, Artemisia argyi, Mint, Tea tree essential oil.

[0015] Chamomile: It contains bisabolol, flavonoids, can have anti - inflammation, soothe sensitive skin, and relieve vulvar swelling or mild inflammation during menstruation.

[0016] Artemisia argyi: Its volatile oil eucalyptol has antibacterial and insect - repellent effects, can have mild antibacterial effects, and is suitable for those with a relatively cold body constitution.

[0017] Mint: It can adjust the smell, and its cool feeling can relieve the stuffy feeling, and its volatile components have a slight bacteriostatic effect.

[0018] Tea tree essential oil: It has the effects of strong antibacterial and fresh smell.

[0019] Furthermore, take Cinnamomum cassia, Amomum kravanh, Angelica sinensis, Fennel raw materials in a mass ratio of (5 - 8):(1 - 3):(0.1 - 0.3):(0.5 - 1) and extract them respectively. Then, perform embedding treatment on the obtained Cinnamomum cassia extract, Amomum kravanh extract, Angelica sinensis extract, and Fennel extract. The treatment steps are as follows: Mix the Cinnamomum cassia extract, Amomum kravanh extract, Angelica sinensis extract, and Fennel extract to obtain a mixed extract. Mix the mixed extract with an emulsifier to obtain an oil - phase liquid. Pour the oil - phase liquid into a chitosan solution and homogenize to form an emulsion. Add a cross - linker to the emulsion, stir, and dry to obtain a single - layer microcapsule.

[0020] The preparation method of the Cinnamomum cassia extract in this application: Steam distillation method. Pulverize Cinnamomum cassia to 20 - 40 mesh, load it into a distillation kettle. The mass ratio of Cinnamomum cassia to water is 1:8. Heat to 100 °C and distill for 3 - 4 hours. After condensation, collect the upper - layer cinnamon oil to obtain the Cinnamomum cassia extract.

[0021] The preparation method of the Amomum kravanh extract in this application: Cold - soaking method. Soak Amomum kravanh powder in 60% ethanol at room temperature for 48 hours, filter, and then concentrate it under vacuum to obtain the Amomum kravanh extract.

[0022] Preparation method of angelica extract: Angelica powder is defatted with petroleum ether, ultrasonically extracted with 70% ethanol for 30 minutes, and the extract is concentrated and purified with macroporous resin to obtain angelica extract.

[0023] Preparation method of fennel extract: Fennel seeds are crushed and mixed with water, directly heated, and the volatile oil is distilled out with water vapor, and separated after condensation to obtain fennel extract.

[0024] Furthermore, the mass ratio of the mixed extract to chitosan is (30 - 50):1; The emulsifier is one or more of Span 80, glycerol, and lecithin; the mass of the emulsifier accounts for 3 - 8% of the mixed extract; The cross-linking agent is sodium tripolyphosphate (TPP) or glutaraldehyde, and the mass ratio of chitosan to the cross-linking agent is (4 - 8):1; Chitosan is dissolved in an acetic acid solution with a concentration of 1 - 3% to obtain a chitosan solution, and the chitosan concentration is 1 - 5%. In this application, the acetic acid solution is a mixed solution of glacial acetic acid and water, and the acetic acid concentration refers to the volume percentage (v / v), and the chitosan concentration refers to the mass volume percentage (g / L).

[0025] Furthermore, isocyanate is mixed with acetone, and a catalyst is added and stirred until dissolved to obtain a polyurethane prepolymer solution. 30 - 60 wt% of the monolayer microcapsules are dispersed in liquid paraffin to obtain a dispersion liquid. The polyurethane prepolymer solution is slowly added dropwise to the dispersion liquid and stirred, and a chain extender is added dropwise for reaction. The double-layer microcapsules are collected by centrifugation and washed with petroleum ether to remove liquid paraffin, and dried to obtain double-layer microcapsules.

[0026] Furthermore, the mass ratio of isocyanate to acetone is 1:(2 - 5); The isocyanate is diphenylmethane diisocyanate (MDI) or isophorone diisocyanate (IPDI); The catalyst is dibutyltin dilaurate or stannous octoate, and the catalyst is 0.1 - 0.3% of the mass of the isocyanate; The monolayer microcapsules are 3 - 10% of the mass of the liquid paraffin; The mass ratio of the polyurethane prepolymer solution to the dispersion liquid is 1:(1 - 5); The chain extender is one or more of 1,4 - butanediol (BDO), ethylene glycol, and mocap; the molar ratio of isocyanate to the chain extender is (1 - 3):1.

[0027] Furthermore, cyperus rotundus, cnidium monnieri, leonurus artemisia, sophora flavescens, and coptis chinensis are crushed and mixed evenly according to the mass ratio of (4 - 7):(4 - 6):(1 - 3):(1 - 3):(0.1 - 0.3) to obtain a mixture, and a solvent is added for fractional extraction; Cyperus rotundus, Cnidium monnieri, Leonurus japonicus, Sophora flavescens, and Coptis chinensis are pulverized to 20 - 40 mesh; The solvent for the first extraction is ethanol and water, and the mass ratio of ethanol to water is (1 - 4):10. The mass ratio of the mixture to the solvent is 1:(10 - 20). The extraction temperature is 70 - 80°C, and the extraction time is 1 - 2 h. After extraction, filtration is performed to obtain the first extract and the medicinal residues; The medicinal residues are subjected to a second extraction. The solvent for the second extraction is ethanol and water, and the mass ratio of ethanol to water is (7 - 9):10. The mass ratio of the first extract to the solvent is 1:(10 - 20). The extraction temperature is 70 - 80°C, and the extraction time is 1 - 2 h. After extraction, filtration is performed to obtain the second extract, and the first extract and the second extract are mixed to obtain the extract.

[0028] Furthermore, the antibacterial composite and the dispersant are added to a mixed solution of ethanol and water, and stirred to obtain an antibacterial composite solution. The mass ratio of ethanol to water in the mixed solution is 3:(6 - 9).

[0029] Furthermore, the dispersant is Tween 80, and the mass of the dispersant accounts for 0.1 - 1% of the mass of the antibacterial composite; the mass of the antibacterial composite accounts for 0.1 - 10% of the mass of the mixed solution.

[0030] Furthermore, the antibacterial composite solution is coated on the non - woven fabric, and each square meter of the non - woven fabric contains 1 - 30 grams of the antibacterial composite; after drying and cutting, the non - woven fabric containing the antibacterial composite is arranged between the surface layer and / or between the surface layer and the absorbent core layer.

[0031] Furthermore, the non - woven fabric can be arranged above the surface layer, between the surface layer and the absorbent core layer, or used as the surface layer.

[0032] Furthermore, the method of coating the antibacterial composite solution on the non - woven fabric can be selected from conventional methods such as spraying and soaking.

[0033] Furthermore, the non - woven fabric is subjected to surface activation treatment using plasma, and the plasma is oxygen plasma or air plasma; the power for performing the surface activation treatment is 50 - 100 W, and the treatment time is 20 - 120 S.

[0034] The surface layer of the sanitary napkin generally uses non - woven fabric or polyethylene material; the absorbent layer generally selects materials such as fluff pulp and superabsorbent polymer; the bottom film generally selects materials such as PE film and breathable film. Generally, processes such as hot - melt adhesive bonding, hot - pressing process, and ultrasonic welding are selected for connection between the layers.

[0035] In addition to sanitary napkins, this application can also be applied to other products such as wet wipes, pantiliners, pessaries, and cotton tampons.

[0036] The 3D embossing process of the sanitary napkin surface layer produces a micro-protrusion structure, which concentrates stress through friction and reduces the actual trigger pressure.

[0037] This application can bring the following beneficial effects: 1. Through the synergistic effect of natural plant components, the antibacterial sanitary napkin of this application can play the roles of antibacterial, anti-inflammatory, antipruritic, soothing, and deodorizing, which helps to provide women with a healthier and more comfortable menstrual care experience.

[0038] 2. This application uses the microcapsule encapsulation technology to encapsulate the active ingredients, effectively preventing the volatilization and inactivation of volatile components. Cinnamon, cardamom, angelica, and fennel in this application contain volatile oils. The active ingredients are embedded by chitosan. On the one hand, it protects the active ingredients; on the other hand, it plays a slow-release role and prolongs the effective time of plant components.

[0039] 3. This application prepares a double-layer composite wall material. The outer layer uses the high-toughness material polyurethane to meet the high static strength to resist shear force and pressure during production or transportation; the inner layer uses the brittle material chitosan to meet the requirement of rupturing and releasing the core material when locally compressed; the rupture pressure of the microcapsule is controlled between 1-2 N / cm 2 within the range of human contact pressure values, which can keep it intact during normal production and transportation, while the pressure and friction of the body during use can rupture and release the core material.

[0040] 4. The antibacterial complex in this application contains extracts, single-layer microcapsules, and double-layer microcapsules, which have different release times. During use, different components are gradually released, continuously playing antibacterial and soothing roles for a long time.

[0041] 5. After the embedding treatment, multiple components are embedded together, which is easier to be evenly dispersed in the sanitary napkin material, improving the consistency and stability of the overall performance of the sanitary napkin; in addition, the embedded microcapsules can play a slow-release and isolation role, reducing the direct contact between plant extracts and the skin and reducing the irritation to the skin.

[0042] 6. This application uses hierarchical extraction. The first extraction preliminarily extracts some components that are easily soluble in water and low-concentration ethanol, and the second extraction further extracts more components with slightly lower polarity and better solubility in high-concentration ethanol, thereby improving the overall extraction rate of the effective components of the raw materials.

[0043] 7. The non-woven fabric is treated by plasma to increase the surface roughness and active groups, and improve the loading capacity.

[0044] 8. The particle sizes of the single-layer microcapsules and double-layer microcapsules in this application are 10-20 microns, and after spraying, they are evenly embedded in the gaps between the non-woven fabric fibers.

[0045] 9. All the antibacterial complexes of this application use plant extracts, which not only have antibacterial effects but also have many advantages such as antibacterial persistence, product safety, and use comfort. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] The drawings described herein are used to provide a further understanding of this application, and constitute a part of this application. The schematic embodiments and descriptions thereof of this application are used to explain this application and do not constitute an improper limitation to this application. In the drawings: Figure 1 It is a schematic structural diagram of a sanitary napkin in this application. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0047] Unless otherwise specified, the reagents and instruments used in the following examples are all commercially available products.

[0048] For the extraction of cinnamon, cardamom, angelica, and fennel, conventional extraction methods can be selected, such as the following methods: Preparation method of cinnamon extract: Steam distillation method. Crush cinnamon to 20 - 40 mesh, load it into a distillation kettle, the mass ratio of cinnamon to water is 1:8, heat to 100 °C, distill for 3 - 4 hours, and collect the upper - layer cinnamon oil after condensation to obtain cinnamon extract.

[0049] Preparation method of cardamom extract: Cold - soaking method. Soak cardamom powder in 60% ethanol at room temperature for 48 hours, filter and then concentrate under vacuum to obtain cardamom extract.

[0050] Preparation method of angelica extract: Degrease angelica powder with petroleum ether, ultrasonically extract with 70% ethanol for 30 minutes, concentrate the extract and then purify it with macroporous resin to obtain angelica extract.

[0051] Preparation method of fennel extract: Crush fennel seeds and mix them with water, directly heat, the volatile oil is distilled out with water vapor, and the fennel extract is obtained after condensation and separation.

[0052]

Example 1

[0053] (1) Dissolve chitosan (1 / 30 of the mass of the mixed extract) in an acetic acid aqueous solution with a concentration (v / v) of 1% to obtain a chitosan solution with a concentration (g / L) of 1%; (2) After the raw materials are extracted, the cinnamon extract, cardamom extract, angelica extract, and fennel extract are mixed to obtain a mixed extract. The mixed extract is mixed with Span 80 (3% of the mass of the mixed extract) to obtain an oil-phase liquid. The oil-phase liquid is poured into a chitosan solution and homogenized to form an emulsion. Sodium tripolyphosphate (1 / 4 of the mass of chitosan) is added to the emulsion, stirred for 1 h, and dried to obtain single-layer microcapsules; (3) Cyperus rotundus, Cnidium monnieri, Leonurus artemisia, Sophora flavescens, and Coptis chinensis are pulverized to 20 mesh, mixed evenly to obtain a mixed material, and a solvent is added for fractional extraction; The solvent for the first extraction is ethanol and water, and the mass ratio of ethanol to water is 1:10. The mass ratio of the mixed material to the solvent is 1:20, the extraction temperature is 70 °C, the extraction time is 1 h, and after extraction, filtration is carried out to obtain the first extract and the medicinal residue; The medicinal residue is subjected to a second extraction. The solvent for the second extraction is ethanol and water, and the mass ratio of ethanol to water is 7:10. The mass ratio of the first extract to the solvent is 1:10, the extraction temperature is 80 °C, the extraction time is 2 h, and after extraction, filtration is carried out to obtain the second extract. The first extract and the second extract are mixed to obtain an extract; (4) The single-layer microcapsules, the extract, and Tween 80 (0.1% of the sum of the masses of the single-layer microcapsules and the extract) are added to a mixed solution of ethanol and water (the mass ratio of ethanol to water is 3:6). The mass of the mixed solution is 10 times the sum of the masses of the single-layer microcapsules and the extract. After stirring, an antibacterial composite solution is obtained; (5) The non-woven fabric is soaked in the antibacterial composite solution until the non-woven fabric is dry, and each square meter of the non-woven fabric contains 30 g of the antibacterial composite.

[0054] [Example 2] In this example, the mass ratio of the antibacterial composite raw materials cinnamon, cardamom, angelica, fennel, Cyperus rotundus, Cnidium monnieri, Leonurus artemisia, Sophora flavescens, and Coptis chinensis is 8:3:0.3:1:7:6:3:3:0.3.

[0055] (1) Chitosan (1 / 50 of the mixed extract) is dissolved in an aqueous acetic acid solution with a concentration of 3% to obtain a chitosan solution with a concentration of 5%; (2) The cinnamon extract, cardamom extract, angelica extract, and fennel extract are mixed to obtain a mixed extract. The mixed extract is mixed with glycerol (8% of the mass of the mixed extract) to obtain an oil-phase liquid. The oil-phase liquid is poured into the chitosan solution and homogenized to form an emulsion. Glutaraldehyde (1 / 8 of the mass of chitosan) is added to the emulsion, stirred for 1.5 h, and dried to obtain single-layer microcapsules; (3) Cyperus rotundus, Cnidium monnieri, Leonurus artemisia, Sophora flavescens, and Coptis chinensis are pulverized to 40 mesh, mixed evenly to obtain a mixed material, and a solvent is added for fractional extraction; The solvent for the first extraction is ethanol and water, and the mass ratio of ethanol to water is 4:10. The mass ratio of the mixture to the solvent is 1:10. The extraction temperature is 80 °C, the extraction time is 2 h, and after extraction, filtration gives the first extract and the medicinal residue; The medicinal residue is subjected to a second extraction. The solvent for the second extraction is ethanol and water, and the mass ratio of ethanol to water is 9:10. The mass ratio of the first extract to the solvent is 1:20. The extraction temperature is 70 °C, the extraction time is 1 h, and after extraction, filtration gives the second extract. The first extract and the second extract are mixed to obtain the extract; (4) Add the single-layer microcapsules, the extract, and Tween 80 (1% of the sum of the masses of the single-layer microcapsules and the extract) to a mixed solution of ethanol and water (the mass ratio of ethanol to water is 3:9). The mass of the mixed solution is 1000 times the sum of the masses of the single-layer microcapsules and the extract. After stirring, an antibacterial composite solution is obtained; (5) Spray the antibacterial composite solution onto the non-woven fabric until the non-woven fabric is dry. Each square meter of the non-woven fabric contains 1 g of the antibacterial composite.

[0056]

Example 3

[0057] (1) Dissolve chitosan (1 / 40 of the mixed extract) in an aqueous acetic acid solution with a concentration of 2% to obtain a chitosan solution with a concentration of 3%; (2) Mix the cinnamon extract, cardamom extract, angelica extract, and fennel extract to obtain a mixed extract. Mix the mixed extract with lecithin (5% of the sum of the masses of the mixed extract) to obtain an oil-phase liquid. Pour the oil-phase liquid into the chitosan solution and homogenize to form an emulsion. Add sodium tripolyphosphate (1 / 5 of the mass of chitosan) to the emulsion, stir for 2 h, and after drying, obtain single-layer microcapsules; (3) Pulverize cyperus rotundus, cnidium monnieri, motherwort, sophora flavescens, and coptis chinensis to 30 mesh, mix evenly to obtain a mixture, and add a solvent for fractional extraction; The solvent for the first extraction is ethanol and water, and the mass ratio of ethanol to water is 3:10. The mass ratio of the mixture to the solvent is 1:15. The extraction temperature is 75 °C, the extraction time is 1.5 h, and after extraction, filtration gives the first extract and the medicinal residue; The medicinal residues are subjected to a second extraction. The solvent for the second extraction is ethanol and water, and the mass ratio of ethanol to water is 8:10. The mass ratio of the first extract to the solvent is 1:15. The extraction temperature is 75 °C, and the extraction time is 1.5 h. After extraction, filtration is performed to obtain an extract. (4) Add the single-layer microcapsules, the extract, and Tween 80 (0.5% of the sum of the masses of the single-layer microcapsules and the extract) to a mixed solution of ethanol and water (the mass ratio of ethanol to water is 3:8). The mass of the mixed solution is 100 times the sum of the masses of the single-layer microcapsules and the extract. After stirring, an antibacterial composite solution is obtained. (5) Spray the antibacterial composite solution onto the non-woven fabric until the non-woven fabric is dry, and each square meter of the non-woven fabric contains 10 grams of the antibacterial composite.

[0058]

Example 4

[0059]

Example 5

[0060]

Example 6

[0061]

Example 7

[0062] (5) Use oxygen plasma to activate the surface of the non-woven fabric. The power of the surface activation treatment is 100 W, and the treatment time is 20 s. Spray the antibacterial composite solution onto the surface-treated non-woven fabric until the non-woven fabric is dry, and each square meter of the non-woven fabric contains 10 grams of the antibacterial composite.

[0063]

Example 8

[0064] (5) Use air plasma to activate the surface of the non-woven fabric. The power of the surface activation treatment is 50 W, and the treatment time is 120 s. Spray the antibacterial composite solution onto the surface-treated non-woven fabric until the non-woven fabric is dry, and each square meter of the non-woven fabric contains 10 grams of the antibacterial composite.

[0065]

Example 9

[0066] (5) The surface of the non-woven fabric was activated using oxygen plasma. The power of the surface activation treatment was 80 W and the treatment time was 60 s. The antibacterial composite solution was sprayed onto the surface-treated non-woven fabric until the non-woven fabric was dry, and 10 grams of the antibacterial composite was contained in each square meter of the non-woven fabric.

[0067]

Example 10

[0068] The original step (4) was modified as follows: Diphenylmethane diisocyanate was mixed with acetone (mass ratio 1:2), and dibutyltin dilaurate (0.1% of the mass of the isocyanate) was added and stirred until dissolved to obtain a polyurethane prepolymer solution. Cinnamon extract, cardamom extract, angelica extract, and fennel extract were dispersed in liquid paraffin (the sum of the masses of cinnamon extract, cardamom extract, angelica extract, and fennel extract was 3% of the mass of the liquid paraffin) to obtain a dispersion. The polyurethane prepolymer solution (mass ratio to the dispersion 1:1) was slowly added dropwise to the dispersion and stirred, and 1,4-butanediol (molar ratio of isocyanate to chain extender 1:1) was added dropwise and reacted for 2 hours. The double-layer microcapsules were collected by centrifugation, washed with petroleum ether to remove the liquid paraffin, and dried.

[0069]

Example 11

[0070]

Example 12

[0071]

Comparative Example 1

[0072]

Comparative Example 2

[0073]

Comparative Example 3

[0074]

Comparative Example 4

[0075]

Comparative Example 5

[0076]

Comparative Example 6

[0077]

Characterization

[0078] It can be analyzed from the above table that if the artemisia argyi extract, mentha haplocalyx extract, and tea tree essential oil are not encapsulated, the obtained antibacterial composite has no sustained-release function, resulting in an increase in skin irritation; In addition, the composition and ratio of the composition of the present invention have an impact on the skin irritation results.

[0079] 2. Antibacterial test The experimental strains were Staphylococcus aureus (ATCC6538), Escherichia coli (ATCC25922), and Candida albicans (ATCC10231). The antibacterial test method referred to Appendix C, Product Antibacterial Properties, of GB15979 Hygiene Standards for Disposable Sanitary Products. The specific steps were as follows: (1) Cut the non-woven fabrics coated with the antibacterial composite in the examples and comparative examples into specimens of 1.0 cm * 1.0 cm; (2) Put the above specimens into 250 mL Erlenmeyer flasks, add 70 mL of PBS and 5 mL of bacterial suspension respectively, so that the concentration of the bacterial suspension is 1×10 6 ~9×10 6 cfu / mL. Fix the Erlenmeyer flasks on the oscillator shaker and shake at 300 r / min. Replace the fresh bacterial suspension every 2 hours; For Candida albicans, take 0.5 mL of the oscillated sample solution at 1 h, 6 h, and 24 h respectively, inoculate it on a petri dish by the agar pouring method, and culture it at 37 °C for 24 h, and then perform colony counting. For Staphylococcus aureus and Escherichia coli, only record the colony count at 1 h.

[0080] (4) Repeat the test 3 times, and calculate the antibacterial rate according to the following formula: X = (A - B) / A * 100%, where X is the antibacterial rate, A is the average colony count of the control sample (the control sample is the non-woven fabric not coated with the antibacterial composite); B is the average colony count of the test sample.

[0081]

[0082] For the antibacterial effect against Staphylococcus aureus, Coptis chinensis, Cinnamomum cassia, Sophora flavescens, and Cnidium monnieri are used as the main active ingredients; for the antibacterial effect against Escherichia coli, Coptis chinensis, Cinnamomum cassia, and Foeniculum vulgare are used as the main active ingredients; for the antibacterial effect against Candida albicans, Cinnamomum cassia, Cnidium monnieri, and Sophora flavescens are used as the main active ingredients.

[0083] It can be analyzed from the above table that: the antibacterial composite obtained in this application has a good antibacterial effect, and chitosan encapsulates the active ingredients, and the antibacterial composite also has a long-term antibacterial effect.

[0084] In addition, the components and proportions of the antibacterial composite also have a great influence on the antibacterial effect.

[0085] 3. Supplementary experiment on antibacterial test The experimental strain was Candida albicans (ATCC10231), and the specific steps were as follows: (1) Cut the non-woven fabrics coated with the antibacterial composite in Examples 4 - 6 and Example 10 into specimens of 1.0 cm * 1.0 cm; (2) Simulate the state of squeezing the double-layer microcapsules during human movement, use a 500 g weight, corresponding to 1.6 N / CM2 , vertically press the sample 10 times, (3) Put the above sample into a 250 mL Erlenmeyer flask, add 70 mL of PBS and 5 mL of bacterial suspension respectively, so that the concentration of the bacterial suspension is 1×10 6 ~9×10 6 cfu / mL, fix the Erlenmeyer flask on an oscillator shaker, shake it at 300 r / min, and replace the fresh bacterial suspension every 2 hours; (4) Take 0.5 mL of the oscillated sample solution at 1 h, 6 h, and 24 h respectively, inoculate the petri dish by the agar pouring method, and culture it at 37 °C for 24 h, and then perform colony counting; (5) Repeat the experiment 3 times, and calculate the antibacterial rate according to the following formula: X=(A - B) / A*100%, where X is the antibacterial rate, A is the average colony count of the control sample (the control sample is a non-woven fabric without coating the antibacterial composite); B is the average colony count of the test sample.

[0086] 4. Stability For the non-woven fabrics coated with the antibacterial composite obtained in the examples and comparative examples, rub them with sandpaper and observe the shedding of the micro antibacterial composite.

[0087]

[0088] It can be analyzed from the above table that: through the double-layer embedding technology, the microcapsules can resist the shock during production and transportation. During use, due to the changes in body positions such as sitting, walking, and lying of the human body, the microcapsules are squeezed during movement to release the core material, achieving the effect of long-term antibacterial, and it is very suitable for use in sanitary napkin products with small quantity and night use.

[0089] In addition, the stability of the antibacterial composition of the present application on the non-woven fabric is also relatively good; the components and proportions of the antibacterial composition will also affect the stability of the combined group dispersed on the non-woven fabric.

[0090]

Application Scenario

[0091] In order to prevent the addition of the antibacterial composite from blocking the micropores on the surface layer of the sanitary napkin and affecting the air permeability, the antibacterial composite should be avoided from directly contacting the core absorption area 1. As shown in the attachment, if the non-woven fabric is used as the surface layer, the antibacterial composite is coated on the non-core absorption area 2 of the non-woven fabric; if the non-woven fabric is not used as the surface layer, then punch holes in the non-woven fabric coated with the antibacterial composite so that it adheres to the sanitary napkin and exposes the core absorption area. Figure 1 As shown in the attachment, if the non-woven fabric is used as the surface layer, the antibacterial composite is coated on the non-core absorption area 2 of the non-woven fabric; if the non-woven fabric is not used as the surface layer, then punch holes in the non-woven fabric coated with the antibacterial composite so that it adheres to the sanitary napkin and exposes the core absorption area.

[0092] The connection between the non-woven fabric added with the antibacterial composite and the adjacent layer can be achieved through processes such as hot melt adhesive bonding, hot pressing process, ultrasonic welding, etc.; if there is a concern that the high production temperature may damage the activity of the antibacterial composite, the bonding temperature can be reduced, or a spot pressing or edge pressing method can be adopted.

[0093] Each embodiment in this specification is described in a progressive manner. For the same or similar parts among the embodiments, reference can be made to each other, and each embodiment focuses on the differences from other embodiments. In particular, for the system embodiment, since it is basically similar to the method embodiment, the description is relatively simple, and the relevant parts can be referred to the description of the method embodiment.

[0094] The above are only the embodiments of the present application and are not used to limit the present application. For those skilled in the art, various changes and modifications can be made to the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included within the scope of the claims of the present application.

Claims

1. An antibacterial sanitary napkin, characterized in that, It includes a surface layer, an absorbent core layer, and a bottom film. The absorbent core layer is located between the bottom film and the surface layer. An antibacterial composite is added between the surface layer and / or between the surface layer and the absorbent core layer. The antibacterial composite includes the following raw materials: cinnamon, cyperus rotundus, cnidium monnieri, motherwort, cardamom, sophora flavescens, fennel, coptis chinensis, and angelica sinensis.

2. The antibacterial sanitary napkin according to claim 1, wherein Cinnamon, cardamom, angelica sinensis, and fennel raw materials are taken in a mass ratio of (5 - 8):(1 - 3):(0.1 - 0.3):(0.5 - 1) and then extracted separately. The cinnamon extract, cardamom extract, angelica sinensis extract, and fennel extract obtained by extraction are subjected to embedding treatment. The treatment steps are as follows: The cinnamon extract, cardamom extract, angelica sinensis extract, and fennel extract are mixed to obtain a mixed extract. The mixed extract is mixed with an emulsifier to obtain an oil-phase liquid. The oil-phase liquid is poured into a chitosan solution and homogenized to form an emulsion. A cross-linking agent is added to the emulsion, stirred, and dried to obtain monolayer microcapsules.

3. The antibacterial sanitary napkin according to claim 2, characterized in that, Isocyanate is mixed with acetone, and a catalyst is added and stirred until dissolved to obtain a polyurethane prepolymer solution. 30 - 60 wt% of the monolayer microcapsules are dispersed in liquid paraffin to obtain a dispersion. The polyurethane prepolymer solution is slowly added dropwise to the dispersion and stirred. A chain extender is added dropwise for reaction. The double-layer microcapsules are collected by centrifugation, washed with petroleum ether to remove the liquid paraffin, and dried.

4. The antibacterial sanitary napkin according to claim 2, characterized in that, The mass ratio of the mixed extract to chitosan is (30 - 50):1; The emulsifier is one or more of Span 80, glycerol, and lecithin; the mass of the emulsifier accounts for 3 - 8% of the mass of the mixed extract; The cross-linking agent is sodium tripolyphosphate or glutaraldehyde, and the mass ratio of chitosan to the cross-linking agent is (4 - 8):1; Chitosan is dissolved in an acetic acid solution with a concentration of 1 - 3% to obtain a chitosan solution, and the chitosan concentration is 1 - 5%.

5. The antibacterial sanitary napkin according to claim 3, characterized in that, The mass ratio of isocyanate to acetone is 1:(2 - 5); The isocyanate is diphenylmethane diisocyanate or isophorone diisocyanate; The catalyst is dibutyltin dilaurate or stannous octoate, and the mass of the catalyst is 0.1 - 0.3% of the mass of the isocyanate; The mass of the monolayer microcapsules is 3 - 10% of the mass of the liquid paraffin; The mass ratio of the polyurethane prepolymer solution to the dispersion is 1:(1 - 5); The chain extender is one or more of 1,4 - butanediol, ethylene glycol, and mocap; the molar ratio of isocyanate to the chain extender is (1 - 3):

1.

6. The antibacterial sanitary napkin according to claim 1, wherein, Cyperus rotundus, cnidium monnieri, motherwort, sophora flavescens, and coptis chinensis are pulverized and mixed evenly in a mass ratio of (4 - 7):(4 - 6):(1 - 3):(1 - 3):(0.1 - 0.3) to obtain a mixture, and a solvent is added for fractional extraction; The solvent for the first extraction is ethanol and water, and the mass ratio of ethanol to water is (1 - 4):

10. The mass ratio of the mixture to the solvent is 1:(10 - 20), the extraction temperature is 70 - 80 °C, the extraction time is 1 - 2 h, and after extraction, filtration is performed to obtain a first extract and medicinal residues; The medicinal residues are subjected to a second extraction. The solvent for the second extraction is ethanol and water, and the mass ratio of ethanol to water is (7 - 9):

10. The mass ratio of the first extract to the solvent is 1:(10 - 20). The extraction temperature is 70 - 80 °C, and the extraction time is 1 - 2 h. After extraction and filtration, a second extraction solution is obtained. The first extraction solution and the second extraction solution are mixed to obtain an extract.

7. The preparation method of the antibacterial sanitary napkin according to any one of claims 1-6, characterized in that, The antibacterial complex and the dispersant are added to a mixed solution of ethanol and water, and stirred to obtain an antibacterial complex solution. The mass ratio of ethanol to water in the mixed solution is 3:(6 - 9).

8. The preparation method according to claim 7, characterized in that, The dispersant is Tween 80. The mass of the dispersant accounts for 0.1 - 1% of the mass of the antibacterial complex; the mass of the antibacterial complex accounts for 0.1 - 10% of the mass of the mixed solution.

9. A preparation method according to claim 7, characterized in that, The antibacterial complex solution is coated on the non-woven fabric. Each square meter of the non-woven fabric contains 1 - 30 grams of the antibacterial complex; after drying and cutting, the non-woven fabric containing the antibacterial complex is disposed between the surface layer and / or between the surface layer and the absorbent core layer.

10. A preparation method according to claim 9, characterized in that, The non-woven fabric is subjected to surface activation treatment by plasma. The plasma is oxygen plasma or air plasma; the power for the surface activation treatment is 50 - 100 W, and the treatment time is 20 - 120 S.

Images