Shampoo capable of preventing hair loss, removing dandruff and controlling oil

Abstract

The invention relates to an anti-hair-loss anti-dandruff oil-control shampoo, which comprises: a cleaning agent, a foaming agent, a thickening agent, a humectant, an oil-control agent, a softener and an anti-dandruff agent, the cleaning agent comprises 11.2% of sodium laureth sulfate, 0.021% of sodium benzoate, and 0.2% of sodium isostearoyl lactylate; the foaming agent comprises 0.69% of disodium cocoamphodiacetate and 0.26% of sodium chloride; compared with the prior art, the Chinese soapberry fruit extract and the ginseng root extract are used as oil control agents, Chinese soapberry is a natural plant, and the Chinese soapberry fruit extract is relatively mild, small in irritation to skin and hair, rich in saponin components and good in surface activity effect.

Description

Technical Field

[0001] The present invention belongs to the field of cleaning products, and particularly relates to an anti-dandruff and oil-control shampoo. Background Art

[0002] Shampoo, also known as hair shampoo, is a daily necessity for cleaning hair. Shampoo contains various ingredients, and the combined action of these ingredients can clean the scalp and hair. However, although the existing shampoos in the current technology can clean the hair, the oil-control effect is not ideal. Although oil-control agents such as silicone-based, surfactant-based, and high-molecular polymer-based are added, they have certain irritation to the scalp, and allergic reactions will occur after sensitive scalp people use them. Summary of the Invention

[0003] The purpose of the present invention is to provide an anti-dandruff and oil-control shampoo with less irritation, suitable for various hair qualities and sensitive scalps.

[0004] To achieve the above purpose, the technical solution adopted by the present invention is an anti-dandruff and oil-control shampoo, including: a detergent, a foaming agent, a thickening agent, a moisturizing agent, an oil-control agent, a softening agent, and an anti-dandruff agent;

[0005] Among them, the detergent includes 11.2% of sodium lauryl polyether sulfate, 0.021% of sodium benzoate, and 0.2% of sodium isostearoyl lactyl lactate; the foaming agent includes 0.69% of disodium cocoamphodiacetate, 0.26% of sodium chloride, and 0.05% of hexylene glycol; the oil-control agent includes 0.34% of sapindus mukorossi fruit extract, 0.06% of ginseng root extract, and 0.04% of 1,2-hexanediol; the softening agent includes 0.0375% of lauryl polyether, 0.003% of ethylhexylglycerin, 0.0375% of TEA dodecylbenzenesulfonate, 0.52% of dimethicone copolyol, 0.004% of cocamidopropyl betaine, 0.004% of C12-15 pareth-3, and 0.004% of guar hydroxypropyltrimonium chloride; the anti-dandruff agent includes 0.2% of zinc pyrithione ethanolamine salt.

[0006] Furthermore, the hair conditioner includes ginger root extract, skullcap root extract, chamomile flower extract, and tea extract.

[0007] Furthermore, the hair conditioner also includes butylene glycol, phenoxyethanol, and p-hydroxyacetophenone.

[0008] Furthermore, an anti-hair-loss agent, and the anti-hair-loss agent is Platycladus orientalis leaf extract.

[0009] Furthermore, the thickening agent includes coconut oil amide MEA, acrylamidopropyltrimonium chloride, and acrylamide copolymer.

[0010] Further, the humectant includes one or more of hydrogenated starch hydrolyzate, panthenol, adenosine, and phenoxyethanol.

[0011] A method for manufacturing an anti-dandruff and oil-control shampoo as described in any one of claims 1 to 6, characterized by comprising the following steps;

[0012] S1. Disperse TEA salt of dodecylbenzenesulfonic acid, laureth-23, phenoxyethanol, and ethylhexylglycerin into water, and rapidly stir at room temperature until dissolved to obtain a basic solution;

[0013] S2. Heat the basic solution to 85 °C, and sequentially add the extract of Platycladus orientalis leaves and fragrance, and keep warm and stir until completely dissolved;

[0014] S3. Take another beaker, mix sodium laureth sulfosuccinate, sodium benzoate, cocoamphodiacetate disodium, sodium chloride, hexylene glycol, and water to obtain a mixed solution,

[0015] Then put the extract of Sapindus mukorossi Gaertn. fruit, the extract of Panax ginseng root, and 1,2-hexanediol into the mixed solution, disperse and dissolve at 85 °C, and then cool it to below 40 °C for standby;

[0016] S4. Cool the solution in step 2 to below 40 °C, make up the water, add cocoamidopropyl betaine, C12-15 pareth-3, phenoxyethanol, and guar hydroxypropyltrimonium chloride, and stir evenly;

[0017] S5. Pre-dissolve cocoamide MEA with 10% water, and then add it to the solution in step 4, and stir evenly at room temperature;

[0018] S6. Sequentially add sodium lauryl ether sulfate, cocoamidopropyl betaine, sodium chloride, and sodium benzoate to the solution obtained in step 5, and stir evenly;

[0019] S7. Add the solution obtained in step 3 to the solution obtained in step 6, and stir evenly at room temperature;

[0020] S8. Dissolve the suspending agent and preservative with water in advance, and then add them to the solution obtained in step 7, and stir evenly at room temperature.

[0021] Preferably, the suspending agent includes hydrogenated castor oil, sodium methyl cocoyl taurate, polyglyceryl-10, glycerin, dipropylene glycol, and p-hydroxyacetophenone.

[0022] Preferably, the preservative includes 0.6% phenoxyethanol.

[0023] Compared with the prior art, the beneficial effects of the present invention are as follows: By using sapindus fruit extract and ginseng root extract as oil-control agents, sapindus is a natural plant, and its fruit extract is relatively mild, with less irritation to the skin and hair. It contains rich saponin components, has good surface activity, can effectively clean the oil, dirt and dandruff on the scalp and hair, make the hair fresh and clean, has certain antibacterial and anti-inflammatory properties, can inhibit the growth of harmful microorganisms on the scalp, reduce the occurrence of scalp inflammation, and contribute to maintaining the healthy state of the scalp. The sapindus fruit extract also contains some natural oils, vitamins and other nutrients, which can nourish the hair, increase the luster and elasticity of the hair, and at the same time have a certain moisturizing effect to prevent the hair from drying and splitting.

[0024] The ginseng root extract contains various nutrients such as ginsenosides, polysaccharides, amino acids, and vitamins. These components can deeply nourish the scalp and hair, provide necessary nutrients for the hair, and promote the healthy growth of the hair. Detailed implementation mode

[0025] The technical solutions in the embodiments of the present invention are clearly and completely described below. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments.

[0026] An anti-hair loss and anti-dandruff oil-control shampoo, comprising 64.338% of water, 22.2% of a detergent, 2% of a foaming agent, 2% of an oil-control agent, 2.3% of a softener, 0.8% of an anti-hair loss agent (the anti-hair loss agent is platycladus orientalis extract), 0.8% of an aromatic agent, 0.7% of a suspending agent, 1.1% of a preservative, 0.503% of a hair conditioner, etc.

[0027] The detergent therein includes 11.2% of sodium lauryl polyether sulfate, 0.021% of sodium benzoate, and 0.2% of sodium isostearoyl lactyl lactate;

[0028] The foaming agent includes 0.69% of disodium cocoamphodiacetate, 0.26% of sodium chloride, and 0.05% of hexylene glycol;

[0029] The thickener is 0.04%-1.5% of coconut amide MEA, acrylamidopropyltrimethylammonium chloride, acrylamide copolymer, and the moisturizer is 0.01%-0.5% of panthenol, phenoxyethanol;

[0030] The oil-control agent includes 0.34% of sapindus fruit extract, 0.06% of ginseng root extract, and 0.04% of 1,2-hexanediol;

[0031] The fabric softener contains 0.0375% of lauryl polyether, 0.003% of ethylhexyl glycerin, 0.0375% of TEA salt of dodecylbenzenesulfonic acid, 0.52% of polydimethylsiloxanol, 0.004% of cocamidopropyl betaine, 0.004% of C12-15 pareth-3 and 0.004% of guar hydroxypropyltrimonium chloride;

[0032] The antidandruff agent contains 0.2% of piroctone olamine.

[0033] The hair conditioner contains 0.0175% of ginger root extract, 0.00035% of skullcap root extract, 0.0001% of chamomile flower extract and 0.0001% of tea extract, 0.1184% of butanediol, 0.000012% of phenoxyethanol and 0.00005% of p-hydroxyacetophenone.

[0034] The thickeners in the shampoo also include cocamide MEA, acrylamidopropyltrimonium chloride, acrylamide copolymer, etc.

[0035] The moisturizers include one or more of hydrogenated starch hydrolysates, panthenol, adenosine and phenoxyethanol.

[0036] This application uses sapindus fruit extract and ginseng root extract, which are less irritating to the skin and hair, suitable for various hair qualities and sensitive scalps. And the sapindus fruit contains rich saponin components, which have good surface activity, can effectively clean the oil, dirt and dandruff on the scalp and hair, make the hair fresh and clean, have certain antibacterial and anti-inflammatory properties, can inhibit the growth of harmful microorganisms on the scalp, reduce the occurrence of scalp inflammation, and help maintain the healthy state of the scalp. The sapindus fruit extract also contains some natural oils, vitamins and other nutrients, which can nourish the hair, increase the luster and elasticity of the hair, and at the same time have a certain moisturizing effect to prevent the hair from drying and splitting.

[0037] The ginseng root contains various nutrients such as ginsenosides, polysaccharides, amino acids, vitamins, etc. These components can deeply nourish the scalp and hair, provide necessary nutrients for the hair, promote the healthy growth of the hair, can stimulate the blood circulation of the scalp, enhance the vitality of hair follicles, help the hair better absorb nutrients, so that the hair is more tough and strong, reduce hair loss and breakage, have strong antioxidant effects, can scavenge free radicals in the scalp and hair, slow down the aging process of the hair, prevent the hair from becoming withered and fragile, keep the hair in a young state, help regulate the oil secretion of the scalp, make the scalp oil secretion reach a balanced state, reduce oil secretion for oily hair quality, and play a moisturizing role for dry hair quality, making the hair keep fresh and shiny.

[0038] When preparing the above anti-dandruff and oil-control shampoo, the following steps are generally adopted;

[0039] S1. Disperse TEA dodecylbenzenesulfonate, laureth-23, phenoxyethanol and ethylhexylglycerin in water, and stir rapidly at room temperature until dissolved to obtain a basic solution;

[0040] S2. Heat the basic solution to 85 °C, and successively add Platycladus orientalis leaf extract and essence, and keep warm and stir until completely dissolved;

[0041] S3. Take another beaker, mix disodium laureth sulfosuccinate, sodium benzoate, cocoamphodiacetate disodium, sodium chloride, hexylene glycol and water to obtain a mixed solution,

[0042] Then put Sapindus mukorossi fruit extract, Panax ginseng root extract and 1,2-hexanediol into the mixed solution, disperse and dissolve at 85 °C, and then cool it to below 40 °C for standby;

[0043] S4. Cool the solution in step 2 to below 40 °C, make up the water, add cocoamidopropyl betaine, C12-15 pareth-3, phenoxyethanol and guar hydroxypropyltrimonium chloride, and stir evenly;

[0044] S5. Pre-dissolve cocoamide MEA with 10% water, and then add it to the solution in step 4, and stir evenly at room temperature;

[0045] S6. Successively add sodium lauryl ether sulfate, cocoamidopropyl betaine, sodium chloride and sodium benzoate to the solution obtained in step 5, and stir evenly;

[0046] S7. Add the solution obtained in step 3 to the solution obtained in step 6, and stir evenly at room temperature;

[0047] S8. Dissolve the suspending agent and preservative with water in advance and add them to the solution obtained in step 7, and stir evenly at room temperature;

[0048] Finally, after passing the inspection, it is canned.

[0049] It should be noted that the suspending agent includes hydrogenated castor oil, sodium methyl cocoyl taurate, polyglyceryl-10, glycerin, dipropylene glycol and p-hydroxyacetophenone, and the preservative includes 0.6% phenoxyethanol.

[0050] This product is tested in a human trial experiment;

[0051] I. Materials and Methods

[0052] 1. Test substance: The original product of the final cosmetic product.

[0053] 2. Subjects: A total of 30 people, including 6 males and 24 females, aged 18 to 59 years old, with an average age of 36.47 ± 13.52 years, meeting the volunteer inclusion criteria for subjects.

[0054] 3. Trial method: Let the subjects directly use the test product according to the usage characteristics and methods indicated on the label of the cosmetic product. Observe or conduct a telephone follow-up on the skin reactions of the subjects once a week, and record the results according to the grading standard of skin adverse reactions in the Human Trial Test of Cosmetics Safety and Technical Specifications (2015 Edition). The trial period is not less than 4 weeks.

[0055] II. Test Results

[0056] Results of the Human Trial Test of Anti-Hair Loss Cosmetics

[0057]

[0058] Note: See the attachment for the skin reaction conditions of 30 subjects at different observation times.

[0059] The results of the human trial test showed that 0 out of 30 people had skin adverse reactions.

[0060] Skin Reaction Conditions of 30 Subjects at Different Observation Times

[0061]

[0062]

[0063] Note: The results of the first 30 valid subjects were statistically analyzed using the systematic sampling method.

[0064] In addition, the anti-hair loss function of this product was tested.

[0065] I. Materials and Methods

[0066] 1. Test product: The original cosmetic end product.

[0067] 2. Control product: A corresponding test product matrix formula product without anti-hair loss efficacy ingredients, tested in parallel with the test product.

[0068] 3. Elution period product: The same as the control product. During the elution period, both the test group and the control group used the control product.

[0069] 4. Instrument and Equipment

[0070] 4.1 Professional digital camera: The pixel is not less than 15 million, and parameters such as aperture size, sensitivity (ISO), and focal length are kept consistent throughout the entire test process.

[0071] 4.2 Image capture bracket: It can fix the position of the subject's head, keep the top of the head perpendicular to the camera lens, and cooperate with a professional digital camera to take photos of all the hair with the top of the head as the center.

[0072] 4.3 Dermoscope: LED light source, wavelength 450 - 750 nm, color temperature 6500 - 8000 K, illuminance not less than 5401x, magnification ≥20 times, detection diameter not less than 1.0 cm or area not less than 0.8 cm 2 。

[0073] 4.4 Comb: The tooth density is moderate (tooth spacing 0.9 - 1.1 mm), the tooth length is 2.0 - 3.0 cm, the comb length is not less than 10 cm (excluding the comb handle), and the same specification and material of the comb must be used throughout the test process. After each use, it shall be disinfected according to the relevant requirements in the "Technical Specification for Disinfection in Medical Institutions" (WS-T 367-2012).

[0074] 5. Subjects: A total of 60 valid subjects completed the test, aged 24 to 60 years. Among them, there were 30 subjects in the experimental group, 1 male and 29 females, with an average age of 50.23 ± 8.67 years; 3 0 subjects in the control group, 4 male 26 subjects, 51.23±6.48 female subjects, with an average age of

[0075] years. They met the voluntary inclusion and exclusion criteria for subjects.

[0075] 6. Test method: Conduct inspections according to the specific requirements of the current valid technical specification method. Subjects who passed the initial screening needed to undergo a 2-week washout period, and then be screened again after the washout period. Eligible subjects selected for the formal test were divided into an experimental group and a control group by stratified randomization, and the test product and the control product were distributed respectively. Use the products correctly according to the product instructions for 12 weeks. During the test, the subjects were required to keep a usage diary and strictly abide by the restrictive requirements. Visits were conducted before product use (baseline value), and at 4 weeks, 8 weeks, and 12 weeks after use. Each visit included hair loss counting, assessment of local hair density, visual assessment of overall hair density, image capture, and recording. After all visits, the overall hair density was evaluated by image.

[0076] II. Test Results

[0077] Table 1 Results of hair loss counting before and after product use (mean ± standard deviation) Unit: root

[0078]

[0079] Note: The paired t-test (or the Wilcoxon signed-rank test for two related samples) was used for statistical analysis of the test product group. Compared with the baseline value before use, *P < 0.05

[0080] Table 2 Results of the difference in hair loss count before and after product use (mean ± standard deviation). Unit: root

[0081]

[0082] Note: 1. Independent samples t-test (or Wilcoxon rank sum test for two independent samples) was used for statistical analysis. Compared with the control product group, *P<0.05.

[0083] 2. Difference = Test parameter after product use - Test parameter before product use.

[0084] Table 3 Results of local hair density before and after product use (mean ± standard deviation). Unit: root / cm 2

[0085]

[0086] Note: Paired t-test (or Wilcoxon rank sum test for two related samples) was used for statistical analysis of the test product group. Compared with the baseline value before use, *P<0.05

[0087] Table 4 Results of the difference in local hair density before and after product use (mean ± standard deviation). Unit: root / cm 2

[0088]

[0089] Note: 1. Independent samples t-test (or Wilcoxon rank sum test for two independent samples) was used for statistical analysis. Compared with the control product group, *P<0.05.

[0090] 2. Difference = Test parameter after product use - Test parameter before product use.

[0091] Table 5 Results of overall hair density before and after product use [Median (Minimum, Maximum)]. Unit: grade

[0092]

[0093] Note: Wilcoxon rank sum test for two related samples was used for statistical analysis of the test product group. Compared with the baseline value before use, *P<0.05.

[0094] Table 6 Results of the difference in overall hair density before and after product use [Median (Minimum, Maximum)]. Unit: grade

[0095]

[0096] Note: 1. Wilcoxon rank sum test for two independent samples was used for statistical analysis. Compared with the control product group, *P<0.05.

[0097] 2. Difference = Test parameter after product use - Test parameter before product use.

[0098] III. Test Conclusions

[0099] 1. After using the test product, the hair loss count in the test product group showed significant improvement compared to the pre - use baseline value at the 4 - week and 12 - week follow - up time points (P < 0.05), there was no significant difference compared to the pre - use baseline value at the 8 - week follow - up time point, and the difference in hair loss count at each follow - up time point was not significantly different compared to the control product group;

[0100] 2. After using the test product, the local hair density in the test product group showed significant improvement compared to the pre - use baseline value at the 8 - week and 12 - week follow - up time points (P < 0.05), there was no significant difference compared to the pre - use baseline value at the 4 - week follow - up time point, and the difference in local hair density at the 8 - week and 12 - week follow - up time points was significantly higher than that of the control product group (P < 0.05);

[0101] 3. After using the test product, the overall hair density in the test product group showed significant improvement compared to the pre - use baseline value at the 12 - week follow - up time point (P < 0.05), there was no significant difference compared to the pre - use baseline value at the 4 - week and 8 - week follow - up time points, and the difference in overall hair density at the 8 - week and 12 - week follow - up time points was significantly higher than that of the control product group (P < 0.05).

[0102] In summary, under the conditions of this test, the test product has the effect of preventing hair loss.

[0103] Appendix Table 1: Detection Results of the Test Product Group and the Control Product Group (Table of Measurement Data Results)

[0104]

[0105]

[0106]

[0108] Continued Appendix Table 1: Detection Results of the Test Product Group and the Control Product Group (Table of Measurement Data Results)

[0109]

[0110]

[0111] Appendix Table 2: Detection Results of the Test Product Group and the Control Product Group (Table of Ranked Data Results)

[0112]

[0113]

[0114]

[0115] As described above, it is only the specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention can easily think of changes or substitutions, which should all be covered by the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims described above.

Claims

1. An anti-dandruff and oil-control shampoo, characterized in that , including: A cleaning agent, the cleaning agent including 11.2% sodium lauryl polyether sulfate, 0.021% sodium benzoate, 0.2% sodium isostearoyl lactyl lactate; A foaming agent, the foaming agent including 0.69% disodium cocoamphodiacetate, 0.26% sodium chloride, 0.05% hexylene glycol; A thickening agent of 0.04% - 1.5%, a humectant of 0.01% - 0.5%; An oil-control agent, the oil-control agent including 0.34% sapindus mukorossi fruit extract, 0.06% ginseng root extract, 0.04% 1,2 - hexanediol; A softening agent, the softening agent including 0.0375% lauryl polyether, 0.003% ethylhexylglycerin, 0.0375% TEA - dodecylbenzenesulfonate, 0.52% polydimethylsiloxanol, 0.004% cocoamidopropyl betaine, 0.004% C12 - 15 pareth - 3, and 0.004% guar hydroxypropyltrimonium chloride; An anti - dandruff agent, the anti - dandruff agent including 0.2% piroctone olamine; 2. The anti-dandruff and oil-control shampoo according to claim 1, characterized in that, It also includes: A hair conditioning agent, the hair conditioning agent including ginger root extract, skullcap root extract, chamomile flower extract and tea extract.

3. The anti-dandruff and oil-control shampoo according to claim 2, wherein The hair conditioning agent also includes butylene glycol, phenoxyethanol and p - hydroxyacetophenone.

4. The anti-dandruff and oil-control shampoo according to claim 1, characterized in that It also includes: An anti - hair - loss agent, the anti - hair - loss agent being platycladus orientalis leaf extract.

5. The anti-dandruff and oil-control shampoo according to claim 1, characterized in that, The thickening agent includes coconut oil amide MEA, acrylamidopropyl trimethyl ammonium chloride, acrylamide copolymer.

6. The anti-dandruff and oil-control shampoo according to claim 1, characterized in that, The humectant includes one or more of hydrogenated starch hydrolysate, panthenol, adenosine and phenoxyethanol.

7. A manufacturing method of the anti-dandruff and oil-control shampoo according to any one of claims 1 to 6, characterized in that, It includes the following steps; S1. Disperse TEA - dodecylbenzenesulfonate, lauryl polyether - 23, phenoxyethanol and ethylhexylglycerin into water, and stir rapidly at room temperature until dissolved to obtain a basic solution; S2. Heat the basic solution to 85°C, and sequentially add platycladus orientalis leaf extract and essence, and keep warm and stir until completely dissolved; S3. Take another beaker, mix sodium lauryl polyether sulfosuccinate, sodium benzoate, disodium cocoamphodiacetate, sodium chloride, hexylene glycol and water to obtain a mixed solution, then put sapindus mukorossi fruit extract, ginseng root extract and 1,2 - hexanediol into the mixed solution, disperse and dissolve at 85°C, and then cool it to below 40°C for standby; S4. Cool the solution in step 2 to below 40°C, make up the water, add cocoamidopropyl betaine, C12 - 15 pareth - 3, phenoxyethanol and guar hydroxypropyltrimonium chloride, and stir evenly; S5. Pre - dissolve coconut oil amide MEA with 10% water first, and then add it into the solution in step 4, and stir evenly at room temperature; S6. Sequentially add sodium lauryl polyether sulfate, cocoamidopropyl betaine, sodium chloride and sodium benzoate into the solution obtained in step 5, and stir evenly; S7. Add the solution obtained in step 3 into the solution obtained in step 6, and stir evenly at room temperature; S8. Dissolve the suspending agent and preservative with water in advance and add them into the solution obtained in step 7, and stir evenly at room temperature.

8. The manufacturing method of the anti-dandruff and oil-control shampoo according to claim 7, characterized in that, The suspension agent described above includes hydrogenated castor oil, sodium methyl cocoyl taurate, polyglycerol-10, glycerol, dipropylene glycol, and hydroxyacetophenone.

9. The manufacturing method of the anti-dandruff and oil-control shampoo according to claim 7, characterized in that, The preservative described above includes 0.6% phenoxyethanol.

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