Formula and preparation method of external traditional Chinese medicine patch with functions of strengthening spleen, harmonizing stomach, promoting digestion and relieving pain

Abstract

The invention provides a formula and a preparation method of an external traditional Chinese medicine patch with spleen strengthening, stomach harmonizing, digestion promoting and pain relieving functions, and belongs to the field of traditional Chinese medicine formulae, the preparation method comprises the following steps: step 1, taking 9.26% by mass of rhizoma atractylodis, 3.70% by mass of fructus amomi, 18.52% by mass of cinnamon, 18.52% by mass of medicated leaven, 18.52% by mass of clove, 9.26% by mass of fructus evodiae, 18.52% by mass of fried semen raphani and 3.70% by mass of radix aucklandiae; step 2, mixing the taken medicines in a container, drying, crushing and grinding the mixed medicines into fine powder by adopting a stirring and crushing device, and sieving with a 220-240-mesh sieve to obtain fine powder; 3, warm water is added into a container, 3 g of the powdery mixed medicine and the warm water are mixed into paste, and the paste is taken out and spread on the patch. The formula has compatibility advantages and synergistic effects, and can strengthen the spleen and harmonize the stomach.

Description

Technical Field

[0001] The invention relates to the field of traditional Chinese medicine formulas, and in particular to a formula of an external-use traditional Chinese medicine patch capable of strengthening the spleen and stomach, promoting digestion and relieving pain, and a preparation method thereof. Background Art

[0002] Traditional Chinese Medicine believes that the body's qi and blood are transformed by the spleen and stomach from food, making the spleen and stomach the foundation of acquired health. However, irregular eating habits, overeating fatty foods, excessive worry, partial cravings, and uneven hunger and satiety can all harm the spleen and stomach.

[0003] Chinese patent publication number CN105343249A discloses a pharmaceutical composition for strengthening the spleen and stomach, promoting digestion and alleviating pain, and its preparation method. The composition is prepared from the following components, by weight: 2233.3g of Poria cocos, 900g of Caulis Aconiti Lateralis Preparata, 666.7g of Crataegus pinnatifida, and 200g of Citrus reticulatae. The preparation method is also provided. The pharmaceutical composition for strengthening the spleen and stomach, promoting digestion and alleviating pain, and its preparation method are effective for treating spleen and stomach deficiency, loss of appetite, abdominal distension and pain, diarrhea caused by indigestion, and malnutrition in children. Summary of the Invention

[0004] The purpose of the present invention is to provide a formula and preparation method of an external Chinese medicine patch with the functions of strengthening the spleen and stomach, promoting digestion and relieving pain, so as to solve the technical problem that the existing pharmaceutical compositions for strengthening the spleen and stomach, promoting digestion and relieving pain are not effective and cannot be used to treat the spleen and stomach through external Chinese medicine patches.

[0005] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0006] A formula for an external Chinese medicine compress with the effects of strengthening the spleen and stomach, promoting digestion and relieving pain is disclosed. The formula comprises the following components by weight: 9.06-9.46% of atractylodes lancea, 3.50-3.90% of amomum villosum, 18.32-18.72% of cinnamon bark, 18.32-18.72% of senna chinensis, 18.32-18.72% of cloves, 9.06-9.46% of evodia rutaecarpa, 18.32-18.72% of stir-fried radish seeds, and 3.50-3.90% of costus root.

[0007] Furthermore, the weight percentages of the formula are as follows: Atractylodes lancea 9.26%, Amomum villosum 3.70%, cinnamon bark 18.52%, Shenqu 18.52%, cloves 18.52%, Evodia rutaecarpa 9.26%, stir-fried radish seeds 18.52%, and costus root 3.70%.

[0008] A preparation method of an external Chinese medicine compress having the functions of strengthening the spleen and stomach, promoting digestion and relieving pain, comprising the following steps:

[0009] Step 1: Take 10% of Atractylodes lancea, 4% of Amomum villosum, 20% of Cinnamon bark, 20% of Shenqu, and 20% of Clove according to the mass percentage;

[0010] Step 2: Mix the drugs in a container, dry, crush, and grind the mixed drugs using a stirring and crushing device, pass through a 220-240 mesh sieve, and grind into fine powder;

[0011] Step 3: Add warm water to the container, mix 3 grams of powdered mixed medicine with warm water to form a paste, take out the paste and spread it on the patch.

[0012] Furthermore, in step 2, the stirring and crushing device is a powder pulverizer, and the time for crushing the mixed medicine by the powder pulverizer is 15-30 minutes.

[0013] Furthermore, in step 2, before powdering, the medicines are mixed and cleaned, and then air-dried or sun-dried.

[0014] Furthermore, in step 2, the powdered mixture is poured out and filtered using a filter with a mesh size of 220-240 mesh.

[0015] Furthermore, in step 3, the paste is poured out and sterilized at a temperature of 100 to 110° C. for 40 to 60 minutes.

[0016] The present invention's Atractylodes lancea has a pungent, bitter, and warming nature and meridians, and enters the spleen and stomach meridians. Traditional efficacy: It dries dampness and strengthens the spleen, dispels wind and cold. Modern pharmacology: It contains volatile oils (atractylenol and atractylenol), which have anti-ulcer, gastrointestinal motility, and digestive juice secretion-promoting effects. Application: It treats dampness obstructing the middle jiao (abdominal distension, loss of appetite), and improves the spleen and stomach's transport and transformation functions.

[0017] Amomum villosum: Nature and flavor: Pungent, warm; enters the spleen, stomach, and kidney meridians. Traditional effects: Eliminates dampness, promotes qi circulation, warms the middle and stops diarrhea, and stabilizes pregnancy. Modern pharmacology: Its volatile oil (bornyl acetate) inhibits gastric acid secretion, relieves gastrointestinal spasms, and promotes gastric emptying. Uses: Relieves spleen and stomach qi stagnation (abdominal distension and pain, belching) and harmonizes stomach qi.

[0018] Cinnamon: Properties and flavors: Pungent, sweet, and highly warming; it enters the kidney, spleen, heart, and liver meridians. Traditional benefits: Tonifies fire and yang, dispels cold and relieves pain, and warms and unclogs the meridians. Modern pharmacology: Cinnamaldehyde dilates blood vessels, improves gastrointestinal circulation, and enhances intestinal motility. Uses: Treats spleen and stomach deficiency (cold pain, diarrhea), warms the middle jiao, and relieves pain.

[0019] Clove: Nature and Flavor: Pungent, Warming; Enters the Spleen, Stomach, Lung, and Kidney meridians. Traditional Benefits: Warms the middle and reduces adverse reactions, dispels cold and relieves pain. Modern Pharmacology: Eugenol is antibacterial and anti-inflammatory, inhibits gastrointestinal smooth muscle spasms, and promotes gastric mucosal repair. Uses: Relieves vomiting and abdominal pain caused by stomach cold, and synergizes with cinnamon to enhance its warming effect.

[0020] Evodia rutaecarpa: Properties and flavors: Pungent, bitter, and hot; enters the liver, spleen, stomach, and kidney meridians. Traditional effects: Dispels cold and relieves pain, reduces adverse reactions and stops vomiting, and boosts yang and stops diarrhea. Modern pharmacology: Evodiamine is an analgesic and anti-inflammatory agent, inhibits gastric acid secretion, and improves gastrointestinal spasms. Uses: Targeted for cold stagnation in the liver and stomach (cold pain in the abdomen, vomiting, and acid reflux), and is particularly effective in relieving pain.

[0021] Shenqu: Nature and Flavor: Sweet, Pungent, Warming; Enters the Spleen and Stomach Meridians. Traditional Benefits: Helps with digestion and soothes the stomach, invigorates the spleen and stimulates appetite. Modern Pharmacology: Contains amylase, yeast, and volatile oils, promoting the secretion of digestive enzymes and breaking down carbohydrates. Uses: Targeted treatment for indigestion (abdominal bloating, poor appetite), synergistically enhances digestion with stir-fried radish seeds.

[0022] Woody

[0023] Nature and flavor: Pungent, bitter, warm; enters the spleen, stomach and large intestine meridians.

[0024] Efficacy: Promotes qi circulation and relieves pain, strengthens the spleen and aids digestion.

[0025] Modern pharmacology: Volatile oil (costus hydrocarbons) can bidirectionally regulate gastrointestinal motility (antispasmodic or prokinetic) and anti-ulcer.

[0026] Application: Eliminate qi stagnation (abdominal distension, intestinal rumbling) and regulate gastrointestinal function.

[0027] Stir-fried radish seeds

[0028] Nature and flavor: pungent, sweet, neutral; enters the lung, spleen and stomach meridians.

[0029] Efficacy: Helps digestion and relieves bloating, reduces qi and resolves phlegm.

[0030] Modern pharmacology: Mustard oil promotes intestinal peristalsis, accelerates the excretion of food accumulation, and reduces intestinal tension.

[0031] Application: Specializes in treating food stagnation and qi stagnation (belching, acid regurgitation, abdominal distension and constipation), and works synergistically with Shenqu to help digest food and relieve stagnation.

[0032] The present invention has the following beneficial effects due to the adoption of the above technical solution:

[0033] 1. Compatibility advantages and synergistic effects

[0034] ① Strengthen the spleen and stomach

[0035] Core combination: Atractylodes (drying dampness) + Amomum villosum (promoting qi) + Shenqu (digestion) → dispel dampness and restore spleen function. Warming the middle and dispersing cold: Cinnamon (warming yang) + Clove (reducing adverse reactions) + Evodia rutaecarpa (pain relief) → dispel middle-jiao cold pathogenicity and improve symptoms of deficiency and cold.

[0036] ②Digestion and relieving stagnation

[0037] Main effect for eliminating food stagnation: Muxiang (reducing qi and relieving bloating) + Shenqu (enzymatically dissolving food stagnation) → accelerate the excretion of food stagnation and relieve abdominal distension and constipation. Auxiliary effect for promoting qi circulation: Stir-fried Radish Seed (bidirectionally regulating gastrointestinal motility) + Amomum villosum (promoting gastric emptying) → eliminate qi stagnation and restore gastrointestinal motility.

[0038] 2. Analgesic mechanism

[0039] Direct analgesia: Evodia rutaecarpa (inhibits pain signals) + Clove (antispasmodic) → relieves gastrointestinal spasmodic pain.

[0040] Indirect improvement: Cinnamon bark (improves blood flow) + Atractylodes macrocephala (anti-ulcer) → relieve pain by repairing mucosa and promoting circulation.

[0041] 3. Overall evaluation

[0042] This prescription mainly warms the middle and dispels cold, promotes qi and aids digestion, while also drying dampness and strengthening the spleen, relieving spasms and relieving pain. It is suitable for symptoms of spleen and stomach deficiency and cold combined with qi stagnation and dampness obstruction, manifested as:

[0043] Main symptoms: cold pain in the abdomen, bloating after eating, belching and acid reflux, loose stools or constipation.

[0044] Applicable people: patients with chronic gastritis, functional dyspepsia, and irritable bowel syndrome (cold and dampness type).

[0045] Note: The proportion of warming and hot herbs (cinnamon, cloves, and Evodia rutaecarpa) in the prescription is relatively high. If the patient has excess heat or excessive fire due to yin deficiency (dry mouth, red tongue, constipation), it should be used with caution or the combination should be adjusted. DETAILED DESCRIPTION

[0046] To make the objectives, technical solutions, and advantages of the present invention more clearly understood, the present invention is further described in detail with reference to preferred embodiments below. However, it should be noted that many of the details listed in this specification are merely intended to help the reader gain a thorough understanding of one or more aspects of the present invention, and these aspects of the present invention can be practiced even without these specific details.

[0047] A formula for an external Chinese medicine patch with the functions of strengthening the spleen and stomach, promoting digestion and relieving pain, characterized in that the weight percentages of the formula are as follows: 9.26% of Atractylodes lancea, 3.70% of Amomum villosum, 18.52% of Cinnamon bark, 18.52% of Shenqu, 18.52% of Clove, 9.26% of Evodia rutaecarpa, 18.52% of Rhizoma Raphani, and 3.70% of Aucklandia lappa.

[0048] A preparation method of an external Chinese medicine compress having the functions of strengthening the spleen and stomach, promoting digestion and relieving pain, comprising the following steps:

[0049] Step 1: taking Atractylodes lancea, Amomum villosum, cinnamon bark, Shenqu, cloves, Evodia rutaecarpa, stir-fried radish seeds and costus root according to the mass percentage of any one of claims 1-2;

[0050] Step 2: Mix the drugs in a container, dry, crush, and grind the mixed drugs using a stirring and crushing device, pass through a 220-240 mesh sieve, and grind into fine powder;

[0051] Step 3: Add warm water to the container, mix 3 grams of powdered mixed medicine with warm water to form a paste, take out the paste and spread it on the patch.

[0052] In the embodiment of the present invention, in step 2, the stirring and crushing device is a powder pulverizer, and the time for crushing the mixed medicine by the powder pulverizer is 15-30 minutes.

[0053] In the embodiment of the present invention, in step 2, before powdering, the medicines are mixed and cleaned, and then air-dried or sun-dried.

[0054] In the embodiment of the present invention, in step 2, the powdery mixture is poured out and filtered using a filter with a mesh size of 220-240 mesh.

[0055] In the embodiment of the present invention, in step 3, the paste is poured out and sterilized at a temperature of 100-110° C. for 40-60 minutes.

[0056] After applying the patch to 600 cases of abdominal pain caused by indigestion, the clinical symptoms of abdominal pain and poor appetite were significantly improved. After applying the patch to 300 cases of indigestion, the clinical symptoms of indigestion and abdominal pain were cured.

[0057] Matters not covered by the present invention are known technologies.

[0058] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as within the scope of protection of the present invention.

Claims

1. A formula for an external Chinese medicine patch that strengthens the spleen and stomach, promotes digestion and relieves pain, characterized by: The weight percentages of the formula are as follows: 9.06-9.46% of Atractylodes lancea, 3.50-3.90% of Amomum villosum, 18.32-18.72% of Cinnamon bark, 18.32-18.72% of Shenqu, 18.32-18.72% of Clove, 9.06-9.46% of Evodia rutaecarpa, 18.32-18.72% of Fried Radish Seed, and 3.50-3.90% of Costus root.

2. The formula of the Chinese medicine patch for external use having the functions of strengthening the spleen and stomach, promoting digestion and relieving pain according to claim 1, characterized in that: The weight percentages of the formula are as follows: 9.26% of Atractylodes lancea, 3.70% of Amomum villosum, 18.52% of Cinnamon bark, 18.52% of Shenqu, 18.52% of Cloves, 9.26% of Evodia rutaecarpa, 18.52% of Fried Radish Seeds, and 3.70% of Costus root.

3. The preparation method of the Chinese medicinal patch for external use having the functions of invigorating the spleen and stomach, promoting digestion and relieving pain according to claim 1, characterized in that: The preparation method comprises the following steps: Step 1: taking Atractylodes lancea, Amomum villosum, cinnamon bark, Shenqu, cloves, Evodia rutaecarpa, stir-fried radish seeds and costus root according to the mass percentage of any one of claims 1-2; Step 2: Mix the drugs in a container, dry, crush, and grind the mixed drugs using a stirring and crushing device, pass through a 220-240 mesh sieve, and grind into fine powder; Step 3: Add warm water to the container, mix 3 grams of powdered mixed medicine with warm water to form a paste, take out the paste and spread it on the patch.

4. The method for preparing the Chinese medicinal patch for external use having the functions of invigorating the spleen and stomach, promoting digestion and relieving pain according to claim 3, characterized in that: In step 2, the stirring and crushing device is a powder pulverizer, and the time for crushing the mixed medicine by the powder pulverizer is 15-30 minutes.

5. The method for preparing the Chinese medicinal patch for external use having the functions of strengthening the spleen and stomach, promoting digestion and relieving pain according to claim 3, characterized in that: In step 2, before powdering, mix and clean the medicine, and then air dry or sun dry it.

6. The method for preparing the Chinese medicinal patch for external use having the functions of invigorating the spleen and stomach, promoting digestion and relieving pain according to claim 3, characterized in that: In step 2, the powdered mixture is poured out and filtered using a filter with a mesh size of 220-240 meshes.

7. The method for preparing the Chinese medicinal patch for external use having the functions of strengthening the spleen and stomach, promoting digestion and relieving pain according to claim 3, characterized in that: In step 3, the paste is poured out and sterilized at 100-110° C. for 40-60 minutes.