Humidifying assembly and breathing ventilation equipment

Abstract

A breathing ventilation apparatus (110) is provided that is configured to deliver breathing gas to a patient connection device (170). The breathing ventilation apparatus (110) includes: a gas pressurization unit (210) configured to generate pressurized breathing gas; a gas inlet (112) configured to introduce breathing gas to the breathing ventilation device (110); a gas outlet (111) configured to discharge pressurized breathing gas to the breathing tube (160); a detection module (250) configured to detect a pressure of the pressurized breathing gas; at least one non-volatile memory (150) configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers are configured to activate the respiratory ventilation device (110) and / or to activate a program that continuously reads information from the detection module (250) upon a pilot operation and to control the pressure of the pressurized respiratory gas using the information read from the detection module (250) and the at least one parameter.

Description

[0001] This application is a divisional application of the Chinese patent application with application date of October 26, 2018 and application number 201880093168.8. Technical Field

[0002] The present application relates generally to the detection, diagnosis, treatment, prevention, and amelioration of respiratory-related conditions and, more particularly, to systems and methods for delivering breathing gases. Background Art

[0003] Breathing is important for maintaining life in a subject (e.g., a human body). A subject's respiratory system facilitates gas exchange. The subject's nose and / or mouth form the entrance to the subject's airway. A variety of respiratory disorders exist (e.g., apnea, hypopnea, hyperpnea, snoring, etc.). Respiratory disorders can threaten a subject's health (and / or life). Therefore, it is desirable to develop systems and methods for delivering breathing gases to a subject. Summary of the Invention

[0004] In one embodiment, a humidification assembly is configured to humidify pressurized respiratory gas from a respiratory ventilation device, wherein the humidification assembly includes a liquid chamber configured to hold one or more liquids, wherein the liquid chamber includes a housing, a housing cover, and a humidification assembly gas inlet, the humidification assembly gas inlet configured to introduce pressurized respiratory gas into the housing via a first gas channel, wherein the first gas channel includes an outlet.

[0005] In one embodiment, the liquid chamber of the humidification assembly further comprises a humidification assembly gas outlet configured to direct the humidified and pressurized breathing gas back into the body of the respiratory ventilation device via a second gas passageway, wherein the second gas passageway comprises an inlet.

[0006] In one embodiment, the liquid chamber of the humidifying assembly includes an outer shell, wherein the humidifying assembly gas inlet of the liquid chamber and / or the humidifying assembly gas outlet of the liquid chamber are arranged on a first side surface of the outer shell of the liquid chamber, and wherein the first gas channel is used to connect the first gas channel and the outlet of the box, and / or the inlet of the second gas channel for connecting the second gas channel and the box is arranged inside the outer shell of the liquid chamber. In one embodiment, the outer shell includes an inner shell and a cover shell of a layered structure. This layered structure can make the outer shell easy to disassemble and clean.

[0007] By forming the first and second gas channels in the housing of the liquid chamber, the tank may include a simpler design with a wider opening and volume, allowing it to be more easily retained and filled than if filled with water through one gas channel.

[0008] In one embodiment, the outlet of the first gas channel faces the second side surface of the shell of the liquid chamber, the inlet of the second gas channel faces the third side surface of the shell of the liquid chamber, and the second side surface of the shell of the liquid chamber is opposite to the third surface of the shell of the liquid chamber.

[0009] By separating the inlet and outlet, the airflow can travel a longer distance while being exposed to the liquid in the tank, thereby improving humidification efficiency.

[0010] In one embodiment, the liquid chamber includes a guide plate disposed on an upper edge of the outlet of the first gas channel, the guide plate being configured to guide the pressurized breathing gas to flow downwardly to the tank.

[0011] In one embodiment, the first gas channel includes a first portion and a second portion, wherein the first portion of the first gas channel extends from the humidification assembly gas inlet of the liquid chamber to a first common plane, and the second portion of the first gas channel extends from the first common plane to an outlet of the first gas channel. This shape of the gas channel reduces noise emitted from the liquid chamber through the gas channel.

[0012] Additionally or alternatively, according to one embodiment, the second gas channel includes a first portion and a second portion, wherein the first portion of the second gas channel extends from an inlet of the second gas channel to a second common plane, and wherein the second portion of the second gas channel extends from the second common plane to the humidification assembly gas outlet of the liquid chamber.

[0013] By forming the first gas channel and the second gas channel to have a common plane, a compact design can be achieved.

[0014] Additionally or alternatively, the first and second gas channels may have substantially rectangular cross-sections, which may save dead space and / or increase the area of ​​the cross-section compared to a tubular cross-section, thereby allowing for a more compact design and / or lower resistance to the pressurized gas.

[0015] In one embodiment, the first gas channel and the second gas channel intersect each other; wherein the distance between the outlet and the gas inlet of the humidification component is greater than the distance between the outlet and the gas outlet of the humidification component.

[0016] Additionally or alternatively, a distance between the inlet and the humidification assembly gas outlet is greater than a distance between the inlet and the humidification assembly gas inlet.

[0017] By passing through the first and second gas passages, mechanical noise from the gas inlet of the humidification assembly connected to the first gas passage of the main body of the respiratory ventilation device and bubbling noise propagating in the housing and through the second gas passage are reduced due to a compact design that reduces dead space. Liquid in the housing is also less likely to reach the inlet and outlet.

[0018] In one embodiment, the first portion of the first gas channel is substantially parallel to the second portion of the second gas channel along a direction that is angled with respect to the first side surface of the housing of the liquid chamber. Additionally or alternatively, according to one embodiment, the second portion of the first gas channel and the first portion of the second gas channel are arranged in different layers. Additionally or alternatively, according to one embodiment, a first projection of the second portion of the first gas channel on a horizontal plane and a second projection of the first portion of the second gas channel on the horizontal plane intersect or at least partially overlap.

[0019] In one embodiment, the second portion of the first gas channel is disposed below the first portion of the second gas channel, or the first portion of the second gas channel is disposed below the second portion of the first gas channel.

[0020] In one embodiment, an area of ​​a first cross-section of the first gas channel on a first common plane is equal to or less than half an area of ​​a gas inlet of the humidification assembly of the liquid chamber, and / or a second cross-section of the second gas channel on a second common plane is equal to or less than half an area of ​​a gas outlet of the humidification assembly of the liquid chamber.

[0021] In one embodiment, the liquid chamber further includes: a first inclined plate disposed between the first cross-section and the gas inlet of the humidification assembly of the liquid chamber, the first inclined plate being configured to allow the pressurized respiratory gas to flow smoothly in the first gas channel; and a second inclined plate disposed between the second cross-section and the gas outlet of the humidification assembly of the liquid chamber, the second inclined plate being configured to allow the humidified and pressurized respiratory gas to flow smoothly in the second gas channel.

[0022] In one embodiment, the liquid chamber further comprises a connecting plate comprising a first hole and a second hole, wherein the first hole and the second hole correspond to a humidification assembly inlet and a humidification assembly gas outlet of the liquid chamber, respectively, and the connecting plate is configured to allow a sealed connection between the liquid chamber and the main body of the respiratory ventilation device.

[0023] In one embodiment, the liquid chamber further includes: a first groove, which is arranged between the gas inlet of the humidification assembly of the liquid chamber and the connecting plate, and the first groove is configured to accommodate a first portion of one or more liquids and prevent the first portion of the one or more liquids from entering the main body of the respiratory ventilation device when the liquid chamber is tilted; and / or a second groove, which is arranged between the gas outlet of the humidification assembly of the liquid chamber and the connecting plate, and the second groove is configured to accommodate a second portion of the one or more liquids and prevent the second portion of the one or more liquids from entering the main body of the respiratory ventilation device when the liquid chamber is tilted.

[0024] In one embodiment, at least a portion of the bottom of the first gas channel is located below the lower edge of the gas inlet of the humidification component of the liquid chamber, and / or at least a portion of the bottom of the second gas channel is located below the lower edge of the gas outlet of the humidification component of the liquid chamber below.

[0025] The arrangement can prevent fluid (eg condensed water) from being discharged from the gas passage through the gas outlet and / or entering the gas outlet when the tank cover is closed, or reduce such risk.

[0026] In one embodiment, the housing is connected and / or connectable to the housing and / or the housing lid and is pivotally arranged relative to the housing. Since the first gas channel and / or the second gas channel are formed together with the housing, the structure of the housing can be formed in a very simple manner, thereby allowing for better cleaning and liquid filling.

[0027] In one embodiment, the liquid-contacting sidewall of the liquid chamber is at least partially formed by the outer sidewall of the tank of the housing, which forms the outer surface of the humidification assembly. Additionally or alternatively, the housing is formed with only one opening for filling the liquid and replacing the pressurized gas. Compared to some known designs, the liquid chamber and / or housing can be formed in a simpler manner, for example, with a single sidewall, and / or with a substantially open top side, for example, thereby reducing weight and size, increasing the liquid-gas contact surface, and providing easier access to the housing / liquid chamber.

[0028] In one embodiment, the box cover is pivotally connected to the box body via a connecting mechanism; wherein at least a portion of the side surface of the first gas channel close to the connecting mechanism is covered by a side edge of the gas inlet of the humidifying assembly of the liquid chamber in the flow direction, and / or wherein at least a portion of the side surface of the second gas channel close to the connecting mechanism is covered by a side edge of the gas outlet of the humidifying assembly of the liquid chamber in the flow direction.

[0029] Once the lid is opened by pivoting the lid about the rotation axis defined by the connecting mechanism, the side of the first gas channel and / or the second gas channel that is adjacent to the connecting mechanism is shifted to a lower position than the other side of the first gas channel and the second gas channel. By covering at least a portion of such side, liquid in the first gas channel and / or the second gas channel is prevented from flowing or dripping out and damaging, for example, electronic components or dripping onto a surface on which, for example, a humidifier assembly is placed.

[0030] In one embodiment, the box cover is pivotally connected to the box body via the connecting mechanism, and wherein a distance between the connecting mechanism and the gas outlet of the humidification assembly is smaller than a distance between the connecting mechanism and the gas inlet of the humidification assembly.

[0031] Due to the connection mechanism and the lever action, ports closer to the connection mechanism (e.g., a pivotable hinge connection) can have a tighter seal and / or smaller gap tolerance than ports further from the connection mechanism. By arranging the humidification assembly gas outlet closer to the connection mechanism, the seal of the humidification assembly gas outlet is improved, which in some cases may be more critical than the seal of the unhumidified gas entering the humidification assembly through the humidification assembly.

[0032] In one embodiment, the respiratory ventilation device is configured to deliver respiratory gas to a patient interface, the respiratory ventilation device includes the above-mentioned humidification component, and also includes: a gas pressurizing unit, which is configured to generate pressurized respiratory gas by pressurizing the respiratory gas, the gas pressurizing unit is located in the main body of the respiratory ventilation device, the main body of the respiratory ventilation device includes a shell having a first side wall, which is configured to discharge pressurized respiratory gas; a main gas inlet, which is used to introduce respiratory gas into the respiratory ventilation device, the main gas inlet is arranged on the second side wall of the shell of the main body of the respiratory ventilation device; and a main gas outlet, which is configured to discharge the humidified and pressurized respiratory gas to the breathing tube.

[0033] In one embodiment, the primary gas outlet is configured to be disposed on a body of a respiratory ventilation device.

[0034] In one embodiment, the primary gas outlet is provided on the liquid chamber.

[0035] In one embodiment, a first side surface of the housing of the liquid chamber faces a first side wall of the casing of the main body of the respiratory ventilation device.

[0036] In one embodiment, a respiratory ventilation device is configured to deliver respiratory gas to a patient interface, the respiratory ventilation device comprising: a gas pressurization unit positioned in a body of the respiratory ventilation device; a humidification assembly removably connected to the body of the respiratory ventilation device; wherein the humidification assembly comprises: a liquid chamber configured to hold one or more liquids.

[0037] In one embodiment, the liquid chamber comprises a housing and a housing lid, wherein the housing lid is pivotally connected to the housing via a connection mechanism having a rotation axis; wherein the housing comprises an opening for filling at least one of the one or more liquids, wherein the opening is opened by opening the housing lid and / or is closable by closing the housing lid; and wherein the humidification assembly and the main body of the respiratory ventilation device are fluidically connected by closing the housing lid and / or are fluidically disconnected by opening the housing lid.

[0038] By using a pivotable lid, the main body and humidification assembly are fluidically connected to form a flow channel for pressurized gas and / or humidified and pressurized gas. The mechanical connection between the main body and the housing (typically filled with water) can be isolated from the fluid seal, making the mechanical connection between the main body and the housing easier to operate while ensuring that the fluid connection is airtight under pressure. Furthermore, the lever effect of the lid can be used to ensure that the fluid connection is in close proximity to the pressurized gas and easy to operate with minimal force. In some embodiments, the liquid chamber can be mounted directly on the main body of the respiratory ventilation device. The liquid chamber and the main body of the respiratory ventilation device can be fluidically connected via at least one connection port, which forms at least one flow channel between the main body of the respiratory ventilation device and the liquid chamber. The liquid chamber can also include an openable lid. To fill the liquid chamber with liquid, the user simply opens the lid and fills the housing with liquid. When filling, the fluid connection between the liquid chamber and the main body can be disconnected. Consequently, the respiratory ventilation device has a simplified structure and is easy to use. In some embodiments, the main body of the respiratory ventilation device may include a blower for the gas pressurization unit and / or a heating element configured to heat the liquid in the liquid chamber. The heating element may be mounted on a side surface of the main body. The heating element and the main body may be constructed as a single piece, or the heating element may be detachable from the main body. In some embodiments, the housing and lid may be locked when the lid is closed. In some embodiments, the liquid chamber and the heating element may be locked. In some embodiments, the lid may not be locked to the main body, but may be secured to the main body by locking between the housing and lid, and between the housing and main body. When the heating element is mounted in the liquid chamber, the lid can be opened by unlocking it from the housing. This facilitates opening and closing the lid, as well as fluid connection and disconnection between the lid and the main body. It should be noted that any other locking method between the housing and lid can achieve the above functions without unlocking the liquid chamber from the main body.

[0039] In some embodiments, the case and the body are attachable to each other by moving the case relative to the body in an attachment direction, with the angle between the axis of rotation and the attachment direction being between 20°-160°, or in some embodiments, between 45°-135°, or in some further embodiments, between 60°-120°; and / or wherein the case and the body are unlocked from each other by moving the case relative to the body in an unlocking direction, with the angle between the axis of rotation and the unlocking direction being between 20°-160°, or in some embodiments, between 45°-135°, or in some further embodiments, between 60°-120°.

[0040] By arranging the rotation axis relative to the attachment direction in this manner, closing the lid can be done in a direction perpendicular to the rotation axis and with a component in the attachment direction. Therefore, closing the lid toward the case also connects the case to the main body, thereby improving user comfort.

[0041] In some embodiments, the angle between the attachment direction and the unlocking direction is between -45° and 45°, in some other embodiments, the angle is between -30° and 30°, and in some other embodiments, the angle is between -15° and 15°. In one embodiment, the attachment direction and the unlocking direction can be substantially in the same direction. This can be further combined with the axis of rotation to allow the lid to be opened only in a direction substantially opposite to the unlocking direction, thereby preventing the user from accidentally unlocking the case by opening the lid. This improves user comfort.

[0042] In some embodiments, the humidification component and the main body of the respiratory ventilation device can be fluidically connected through at least one connecting port to form at least one flow channel between the main body of the respiratory ventilation device and the liquid chamber; wherein the at least one connecting port includes a gas inlet and a gas outlet; wherein the connecting port includes an axial seal, which is used to fluid-tightly connect the gas inlet and the gas outlet; wherein the inner surface of the axial sealing member at least partially forms the flow channel, and wherein the axial sealing member defines a sealing plane.

[0043] By using an axial sealing member, the sealing member creates less friction during connection and disconnection than, for example, a tapered connector that creates a radial seal, thereby improving user comfort and operational safety.

[0044] In some embodiments, the angle between the sealing plane and the liquid level in the liquid chamber is between -75° and 75°, in some other embodiments, the angle is between -30° and 30°, and in some other embodiments, the angle is between 15° and 65°; and / or wherein the angle between the sealing plane and the attachment direction is between 15° and 165°, in some other embodiments, the angle is between 30° and 150°, and in some other embodiments, the angle is between 45° and 135°, and in still other embodiments, the angle is between 70° and 110°; and / or wherein the angle between the liquid level and the unlocking direction is between 15° and 165°, in some other embodiments, the angle is between 30° and 150°, and in some other embodiments, the angle is between 45° and 135°, and in still other embodiments, the angle is between 70° and 110°.

[0045] By arranging the sealing plane in the manner described relative to the liquid level (e.g., a water level) and / or by arranging the attachment direction in the manner described relative to the liquid level, the risk of liquid spillage during sealing, unlocking, and / or attaching is reduced. The liquid level is the designed level of liquid during normal use of the respiratory ventilation device and humidification assembly.

[0046] In some embodiments, the inner surface of the axial sealing member at least partially forms the flow channel and / or the overlapping portion of the gas inlet and the gas outlet in a sealed state is less than 5 mm, so that the gas inlet can be disconnected from the gas outlet without contacting the gas inlet and the gas outlet; wherein the axial seal includes one or more elastic materials with a Shore hardness of less than 70 (for example, 20-70, 60, etc.) according to ASTMD2240 Typ A, wherein, compared with the state in which the main body and the humidification component are unlocked, the axial seal is axially compressed by 10%-50% and / or 0.5-6 mm (for example, 1-3 mm) in the sealed state.

[0047] In some embodiments, the gas inlet comprises an inlet hole and the gas outlet comprises an outlet hole, wherein the inlet hole and the outlet hole are formed of one or more materials having a higher hardness than the elastomeric material forming the axial sealing member.

[0048] In some embodiments, the axial sealing member is formed around the inlet opening and / or around the outlet opening.

[0049] In some embodiments, the inlet hole and the outlet hole are formed of a material having a higher hardness than the elastic material forming the axial sealing member, and the inlet hole and the outlet hole are spaced apart in the axial direction of the axial seal by the axial sealing member. In some embodiments, the inlet hole and the outlet hole are spaced apart in the axial direction of the axial sealing member by the axial sealing member by at least 1 mm, and in some embodiments, by at least 5 mm, in the sealed and attached state of the humidification assembly. By spacing the inlet hole and the outlet hole in the axial direction, not only is the friction between the gas inlet and outlet minimized, but the collision between the materials forming the inlet hole and the outlet hole having a higher hardness is also minimized, thereby reducing sudden noise during assembly and / or disassembly of the respiratory ventilation device. Shortly before the inlet and outlet holes are connected, the relative movement between the humidification assembly and the main body of the respiratory ventilation device is also buffered by the axial sealing member, which further increases the comfort of the user.

[0050] In some embodiments, the axial sealing member includes multiple components constructed of one or more elastomeric materials and configured such that only dynamic frictional forces exist between the components during coupling or decoupling of the humidification assembly.

[0051] In some embodiments, the axial sealing member includes a sealing lip protruding from at least one of the inlet hole and the outlet hole, wherein the sealing lip is inclined toward the center of the flow channel and is configured to bend toward the center of the flow channel if pressurized and / or compressed by connecting the gas inlet and the gas outlet.

[0052] In some embodiments, the liquid chamber is detachably connected to the main body of the respiratory ventilation device via a push-push mechanism.

[0053] In some embodiments, a pushing direction of the push-push mechanism is substantially perpendicular to a rotational axis of the connecting mechanism, wherein the humidification assembly and the main body of the respiratory ventilation device can be fluidically connected by connecting the case to the main body in the pushing direction when the case is connected to the main body, and by connecting the liquid chamber to the main body in the pushing direction when the case lid is closed.

[0054] In some embodiments, the gas pressurization unit is configured to generate pressurized breathing gas by pressurizing the breathing gas; the main body of the respiratory ventilation device includes a shell, which is provided with a first side wall, and the first side wall is configured to discharge the pressurized breathing gas; the humidification component is used to humidify the pressurized breathing gas; the respiratory ventilation device also includes: a first gas inlet, which is used to introduce the breathing gas into the respiratory ventilation device, and the gas inlet is provided on the second side wall of the shell of the main body of the respiratory ventilation device; and a first gas outlet, which is configured to discharge the humidified and pressurized breathing gas into the breathing tube; wherein the liquid chamber can be opened from the front surface of the respiratory ventilation device; wherein the humidification component also includes a heating plate, which is configured to heat one or more liquids and generate steam to humidify the pressurized breathing gas.

[0055] In some embodiments, the liquid chamber is removably connected to the body of the respiratory ventilation device.

[0056] In some embodiments, the liquid chamber includes: a housing; and a housing cover pivotally connected to the housing via a connecting mechanism.

[0057] In some embodiments, the tank cover includes a second gas inlet configured to introduce pressurized breathing gas from the main body of the respiratory ventilation device into the liquid chamber.

[0058] In some embodiments, the first gas outlet is disposed on the liquid chamber.

[0059] In some embodiments, the respiratory ventilation device further comprises: a connector configured to provide a sealed connection between the case cover and the body of the respiratory ventilation device, the connector comprising an inclined surface facing the case cover, the case cover comprising a corresponding inclined surface facing the connector, and the inclined surface of the case cover comprising the second gas inlet.

[0060] In some embodiments, the connector includes a gasket including a first hole, the first hole corresponding to the second gas inlet of the box cover, so that when the box cover is closed, the box cover is sealed to the main body of the respiratory ventilation device through the gasket, and the first hole and the gas inlet of the box cover can introduce pressurized breathing gas from the main body of the respiratory ventilation device into the liquid chamber.

[0061] In some embodiments, the respiratory ventilation device further comprises: a connector configured to provide a sealed connection between the box cover and the main body of the respiratory ventilation device, the connector comprising a first threaded hose corresponding to the second gas inlet of the box cover.

[0062] In some embodiments, the case cover includes a second gas inlet configured to introduce pressurized breathing gas from the main body of the respiratory ventilation device into the liquid chamber and a second gas outlet configured to discharge humidified and pressurized breathing gas from the liquid chamber back into the main body of the respiratory ventilation device.

[0063] In some embodiments, the respiratory ventilation device further comprises a connector configured to provide a sealed connection between the housing cover and a main body of the respiratory ventilation device.

[0064] In some embodiments, the connecting member includes an inclined surface facing the tank cover, the tank cover includes a corresponding inclined surface facing the connecting member, and the inclined surface of the tank cover includes the second gas inlet and the second gas outlet.

[0065] In some embodiments, the angle between the inclined surface of the connecting member and the horizontal plane is substantially within 45°-60°.

[0066] In some embodiments, the connecting member includes a gasket, the gasket including a first hole and a second hole, the first hole corresponding to the second gas inlet of the box cover, and the second hole corresponding to the second gas outlet of the box cover, so that when the box cover is closed, the box cover is sealed to the main body of the respiratory ventilation device through the gasket, and the first hole and second gas inlet of the box cover can introduce pressurized respiratory gas from the main body of the respiratory ventilation device into the liquid chamber, and the second hole and second gas outlet of the box cover can introduce humidified and pressurized respiratory gas from the liquid chamber back into the main body of the respiratory ventilation device.

[0067] In some embodiments, the connecting member includes a first threaded hose and a second threaded hose, the first threaded hose corresponds to the second gas inlet of the box cover, and the second threaded hose corresponds to the second gas outlet of the box cover.

[0068] In some embodiments, the first threaded hose and the second threaded hose are substantially vertical, and the second gas inlet and the second gas outlet of the box cover are arranged in a horizontal surface facing the first threaded hose and the second threaded hose, so that when the box cover is closed, the box cover is sealedly connected to the main body of the respiratory ventilation device through the first threaded hose and the second threaded hose, and the first threaded hose and the second gas inlet of the box cover can introduce pressurized respiratory gas from the main body of the respiratory ventilation device into the liquid chamber, and the second threaded hose and the second gas outlet of the box cover can introduce humidified and pressurized respiratory gas from the liquid chamber back into the main body of the respiratory ventilation device.

[0069] In some embodiments, the case lid includes a handle and a buckle located on the back of the handle, the case body includes a recess located relative to the handle of the case lid, and when the case lid is closed, the case lid is fastened to the case body by the engagement of the buckle and the recess.

[0070] In some embodiments, the handle is disposed on the front surface of the respiratory ventilation device, and the connection mechanism between the case body and the case lid is disposed on the rear surface of the respiratory ventilation device, such that when the case lid is opened, the lower surface of the case lid is substantially upright and faces the front surface of the respiratory ventilation device.

[0071] In some embodiments, the connection mechanism between the box body and the box cover includes: one or more first connecting members provided on the box body; and one or more second connecting members provided on the box cover, wherein the one or more second connecting members are pivotally connected to the one or more first connecting members.

[0072] In some embodiments, each of the one or more first connectors includes a pin hole, and each of the one or more second connectors includes a pin.

[0073] In some embodiments, each of the one or more second connectors includes a pin hole, and each of the one or more first connectors includes a pin.

[0074] In some embodiments, each of the one or more first connectors includes a first inclined guide surface, each of the one or more second connectors includes a second inclined guide surface, and the first inclined guide surface and the second inclined guide surface are configured to facilitate mounting the box cover on the box body.

[0075] In some embodiments, at least one of the one or more first connectors includes a protruding post, at least one of the one or more second connectors includes a groove, and the groove is configured to accommodate the protruding post and limit the rear rotational movement of the box lid when the box lid is opened to a certain angle.

[0076] In some embodiments, at least one of the one or more second connectors further comprises a guide groove disposed along a portion of a moving path of the protruding post, the guide groove being configured to smooth the movement of the protruding post.

[0077] In some embodiments, the guide groove includes a first end adjacent to the groove and a second end distal to the groove, and a depth of the guide groove gradually changes from a relatively small value at the first end to a relatively large value at the second end.

[0078] In some embodiments, the one or more second connectors include a baffle configured to limit a maximum rotational movement of the case lid when the case lid is opened.

[0079] In some embodiments, a respiratory ventilation device configured to deliver respiratory gas to a patient interface may include: a gas pressurizing unit configured to generate pressurized respiratory gas by pressurizing the respiratory gas, the gas pressurizing unit being positioned in a main body of the respiratory ventilation device, the main body of the respiratory ventilation device including a shell having a first side wall configured to discharge the pressurized respiratory gas; a gas inlet configured to introduce respiratory gas into the respiratory ventilation device, the gas inlet being disposed on a second side wall of the shell of the main body of the respiratory ventilation device; a gas filtering component configured to filter the respiratory gas introduced into the respiratory ventilation device and / or the pressurized respiratory gas discharged from the gas pressurizing unit; and a gas outlet configured to discharge the pressurized respiratory gas into a breathing tube.

[0080] In some embodiments, the gas filtering component may include: a housing that is detachably connected to the gas inlet of the respiratory ventilation device; and one or more gas filtering units installed in the housing, wherein the one or more gas filtering units are configured to filter the respiratory gas entering the respiratory ventilation device.

[0081] In some embodiments, the one or more gas filter units may include a first gas filter unit that is a coarse filter.

[0082] In some embodiments, the one or more gas filter units may include a second gas filter unit that is a fine filter.

[0083] In some embodiments, the housing may include a gas inlet end including a first cover plate having at least one hole and a gas outlet end including a second cover plate having at least one hole.

[0084] In some embodiments, the one or more gas filter units may include a coarse filter and a fine filter, and the coarse filter may be positioned closer to the gas inlet end of the housing than the fine filter.

[0085] In some embodiments, the gas inlet port may have a larger gas inlet area than the gas outlet port.

[0086] In some embodiments, the gas filtering component may further include a baffle having an area smaller than the gas inlet end of the housing, the baffle being installed in the housing and positioned closer to the gas inlet end of the housing than one or more gas cells.

[0087] In some embodiments, the gas outlet end of the housing may be sealed to the gas inlet end of the respiratory ventilation device via a silicone gasket.

[0088] In some embodiments, the gas filtering component may include a third gas filtering unit mounted inside a gas inlet of the respiratory ventilation device, the third gas filtering unit being configured to filter the respiratory gas entering the respiratory ventilation device.

[0089] In some embodiments, the third gas filter unit may include a coarse filter and / or a fine filter.

[0090] In some embodiments, the gas filtering component may include a fourth gas filtering unit configured to filter one or more gases with a pungent odor in one or more gas channels of the respiratory ventilation device, the fourth gas filtering unit including a membrane made of one or more nanomaterials with adsorption capacity.

[0091] In some embodiments, the one or more nanomaterials may include at least one of activated carbon or graphene.

[0092] In some embodiments, the fourth gas filtration unit can be installed outside the gas inlet of the respiratory ventilation device, at the gas inlet of the respiratory ventilation device, inside the gas inlet of the respiratory ventilation device, between the gas inlet of the respiratory ventilation device and the gas inlet of the gas pressurizing unit, at the gas inlet of the gas pressurizing unit, at the gas outlet of the gas pressurizing unit, between the gas outlet of the gas pressurization and the gas outlet of the respiratory ventilation device, and / or at the gas outlet of the respiratory ventilation device.

[0093] In some embodiments, the gas filtering component can include a fifth gas filter unit configured to filter bacteria from one or more gases in one or more gas channels of the respiratory ventilation device.

[0094] In some embodiments, the fifth gas filtration unit can be installed on the outside of the air inlet of the respiratory ventilation device, at the gas inlet of the respiratory ventilation device, inside the gas inlet of the respiratory ventilation device, between the gas inlet of the respiratory ventilation device and the gas inlet of the gas pressurizing unit, at the gas inlet of the gas pressurizing unit, at the gas outlet of the gas pressurizing unit, between the gas outlet of the gas pressurizing unit and the gas outlet of the respiratory ventilation device, and / or at the gas outlet of the respiratory ventilation device.

[0095] In some embodiments, the respiratory ventilation device may further include a humidification assembly configured to humidify the pressurized respiratory gas discharged from the gas pressurizing unit, and the fifth gas filter unit may be installed in the gas passage between the humidification assembly and the gas outlet of the respiratory ventilation device.

[0096] In some embodiments, the respiratory ventilation device may further include: a breathing mask; and a breathing tube configured to direct pressurized breathing gas from a gas outlet of the respiratory ventilation device to the breathing mask.

[0097] In some embodiments, the gas filtering component may include one or more gas filtering units, and at least one of the one or more gas filtering units may be installed in the breathing tube or the breathing mask.

[0098] In some embodiments, the respiratory ventilation device can further include a humidification assembly configured to humidify the pressurized respiratory gas exhausted from the gas pressurization unit.

[0099] In some embodiments, a respiratory ventilation device configured to deliver respiratory gas to a patient interface may include: a gas pressurization unit configured to generate pressurized respiratory gas by pressurizing the respiratory gas, the gas pressurization unit being positioned in the body of the respiratory ventilation device; and a connector configured to secure the gas pressurization unit to the interior space of the body of the respiratory ventilation device and / or to reduce vibration of the gas pressurization unit.

[0100] In some embodiments, the body of the respiratory ventilation device may include a housing having a first sidewall, the first sidewall being configured to discharge pressurized respiratory gas. The respiratory ventilation device may also include: a gas inlet configured to introduce respiratory gas into the respiratory ventilation device, the gas inlet being disposed on a second sidewall of the housing of the body of the respiratory ventilation device; and a gas outlet configured to discharge the humidified and pressurized respiratory gas into a breathing tube.

[0101] In some embodiments, the connector may include: a connecting portion configured to connect to the outlet of the gas pressurizing unit and form a sealed connection between the connector and the gas pressurizing unit; and a fixing portion configured to fix the connector to the internal space of the main body of the respiratory ventilation device and form a tight connection between the connector and the main body of the respiratory ventilation device.

[0102] In some embodiments, the fixing portion may have a sheet-like structure and may include an aperture configured to allow pressurized breathing gas to pass therethrough.

[0103] In some embodiments, the connecting portion may have a tubular structure; the first end of the connecting portion may be fixed to the fixing portion; the second end of the connecting portion may be connected to the outlet of the gas pressurizing unit; and the connecting portion may allow the pressurized respiratory gas to pass through the tubular structure to reach the hole of the fixing portion.

[0104] In some embodiments, the second end of the connecting portion may be an annular double-layered port including an inner layer and an outer layer.

[0105] In some embodiments, the inner layer may be connected to an outer surface of the outlet of the gas pressurizing unit.

[0106] In some embodiments, the outer surface of the outlet of the gas pressurization unit may include one or more protruding bumps, and the inner surface of the inner layer may include one or more corresponding grooves to match the one or more protruding bumps; or, the outer surface of the outlet of the gas pressurization unit may include one or more grooves, and the inner surface of the inner layer may include one or more corresponding protruding bumps to match the one or more grooves.

[0107] In some embodiments, the outer layer may include a first annular flexible structure configured to dampen vibrations of the gas pressurizing unit along an axial direction of the connecting portion.

[0108] In some embodiments, the first annular flexible structure may have at least one of a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or one or more folds.

[0109] In some embodiments, the outer layer may be connected to an inner surface of the outlet of the gas pressurizing unit.

[0110] In some embodiments, the inner surface of the outlet of the gas pressurization unit may include one or more protruding bumps, and the outer surface of the outer layer may include one or more corresponding grooves to match the one or more protruding bumps; or, the inner surface of the outlet of the gas pressurization unit may include one or more grooves, and the outer surface of the outer layer may include one or more corresponding protruding bumps to match the one or more grooves.

[0111] In some embodiments, the inner layer may include a first annular flexible structure configured to reduce vibration of the gas pressurizing unit along an axial direction of the connecting portion.

[0112] In some embodiments, the first annular flexible structure may have at least one of a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or one or more folds.

[0113] In some embodiments, the joint of the inner layer and the outer layer may include a second annular flexible structure configured to reduce vibration of the gas pressurizing unit along a radial direction of the connection portion.

[0114] In some embodiments, the second annular flexible structure may have at least one of a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or one or more folds.

[0115] In some embodiments, the fixing portion and the connecting portion may be integral.

[0116] In some embodiments, opposite sides of the fixing portion may be snapped into two slots of the main body of the respiratory ventilation device.

[0117] In some embodiments, the fixing portion or the connecting portion may include a flexible material.

[0118] In some embodiments, the flexible material may include at least one of an elastic material or a wear-resistant material.

[0119] In some embodiments, the gas outlet may be disposed on a body of the respiratory ventilation device.

[0120] In some embodiments, the gas outlet may be provided on the liquid chamber.

[0121] In some embodiments, the respiratory ventilation device may include one or more gas filter units mounted on the housing; wherein the one or more gas filter units may extend vertically from a lower edge of the gas pressurizing unit to an upper edge of the gas pressurizing unit, and / or wherein the one or more gas filter units may extend horizontally from one side of the gas pressurizing unit to an opposite side of the gas pressurizing unit.

[0122] In some embodiments, a respiratory ventilation device configured to deliver breathing gas to a patient interface may include: a gas pressurization unit configured to generate pressurized breathing gas by pressurizing the breathing gas, the gas pressurization unit positioned in a body of the respiratory ventilation device; and a primary gas outlet configured to discharge the humidified and pressurized breathing gas to a breathing tube.

[0123] In some embodiments, the main body of the respiratory ventilation device may include a shell having a first side wall, which is configured to discharge pressurized respiratory gas; the respiratory ventilation device may also include: a main gas inlet, which is used to introduce the respiratory gas into the respiratory ventilation device, and the main gas inlet is arranged on the second side wall of the shell of the main body of the respiratory ventilation device; and a gas parameter detection component, which is configured to detect one or more gas parameters of the respiratory ventilation device.

[0124] In some embodiments, the gas parameter detection component may include: a collection portion configured to obtain airflow; a first sensor configured to measure the pressure of the airflow; and a first tube configured to guide the airflow from the collection portion to the surface of the first sensor.

[0125] In some embodiments, the first sensor may be a pressure sensor.

[0126] In some embodiments, the first sensor can be integrated into a printed circuit board (PCB) mounted in an interior space of the respiratory ventilation device.

[0127] In some embodiments, the collection portion may face a primary gas outlet of the respiratory ventilation device.

[0128] In some embodiments, the collection portion may include: an inlet disposed on a first surface of the collection portion, the first surface facing a main gas outlet of the respiratory ventilation device; an outlet disposed on a second surface of the collection portion, the second surface being different from the first surface; and a curved channel disposed inside the collection portion, the curved channel being used to connect the inlet and the outlet; wherein the second surface of the collection portion may be sealedly connected to the inner surface of the main body of the respiratory ventilation device; and the inlet may be disposed above the second surface of the collection portion, or the collection portion may protrude from the inner surface of the main body of the respiratory ventilation device to prevent water from flowing in the collection portion.

[0129] In some embodiments, the inlet may be disposed below a top portion of the curved channel to prevent condensed water from flowing through the curved channel and reaching a surface of the first sensor.

[0130] In some embodiments, the inlet can be positioned below an upper edge of a primary gas outlet of the respiratory ventilation device, but above a lower edge of the primary gas outlet of the respiratory ventilation device.

[0131] In some embodiments, the outlet may be positioned below the inlet.

[0132] In some embodiments, the gas parameter detection component may be further configured to detect flow of one or more gases in one or more channels of the respiratory ventilation device.

[0133] In some embodiments, the gas parameter detection component may also include: a second sensor configured to detect a flow signal associated with one or more gases in one or more channels of the respiratory ventilation device; a second tube configured to direct the airflow from the collection portion to the surface of the second sensor; an auxiliary collection port disposed upstream of the one or more gases; and a third tube configured to direct the airflow from the auxiliary collection port to the surface of the second sensor.

[0134] In some embodiments, the first sensor and the second sensor may share the same collecting portion.

[0135] In some embodiments, the second sensor may be a flow sensor.

[0136] In some embodiments, the collecting portion may include silicone.

[0137] In some embodiments, the collecting portion may be detachably connected to the respiratory ventilation device.

[0138] In some embodiments, the respiratory ventilation device may further include a pressure sensor and a flow sensor for snoring detection, and a humidified gas inlet, wherein the humidified gas inlet is configured to introduce pressurized and humidified gas from the humidification component; the pressure sensor and the flow sensor may be connected to a portion located between a main gas outlet of the respiratory ventilation device and the humidified gas inlet via a curved channel.

[0139] In some embodiments, the gas parameter detection assembly can be configured to detect one or more gas parameters of the humidified and pressurized respiratory gas.

[0140] In some embodiments, the respiratory ventilation device may further include a humidification assembly configured to generate humidified and pressurized respiratory gas, and the gas parameter detection assembly may include a collection portion located downstream of the humidification assembly from the pressurized respiratory gas.

[0141] In some embodiments, the inlet of the collection portion may be positioned below an upper edge of the primary gas outlet of the respiratory ventilation device, but above a lower edge of the primary gas outlet of the respiratory ventilation device.

[0142] In some embodiments, a respiratory ventilation device configured to deliver respiratory gas to a patient interface may include: a gas pressurization unit positioned in a body of the respiratory ventilation device; a humidification assembly removably connected to the body of the respiratory ventilation device, the humidification assembly including a liquid chamber configured to hold one or more liquids; wherein the liquid chamber is removably connected to the body of the respiratory ventilation device via a push-push mechanism.

[0143] In some embodiments, the gas pressurization unit can be configured to generate pressurized breathing gas by pressurizing the breathing gas, wherein the main body of the respiratory ventilation device includes a shell having a first side wall, and the first side wall is configured to discharge the pressurized breathing gas; a humidification component, which can be configured to humidify the pressurized breathing gas; the respiratory ventilation device may also include: a gas inlet, which is used to introduce the breathing gas into the respiratory ventilation device, and the gas inlet is arranged on the second side wall of the shell of the main body of the respiratory ventilation device; and a gas outlet, which is configured to discharge the humidified and pressurized breathing gas to the breathing tube.

[0144] In some embodiments, the push-push mechanism may include: a guide groove provided on the main body of the respiratory ventilation device; a slider provided on the main body of the respiratory ventilation device, the slider being located in the guide groove, the slider being capable of moving back and forth along the guide groove in a first direction; and a push rod provided on the liquid chamber, the push rod being capable of moving back and forth in a second direction, the second direction being perpendicular to the first direction; wherein the slider may include a guide block, the guide block including a first inclined surface, a groove and a second inclined surface, the guide block being configured to guide or limit the moving position of the push rod.

[0145] In some embodiments, the inclination direction of the first inclined surface may be different from the inclination direction of the second inclined surface; and a first angle between the first inclined surface and the vertical direction may be greater than a second angle between the second inclined surface and the vertical direction.

[0146] In some embodiments, the guide block may have a frame similar to the letter A.

[0147] In some embodiments, the push-push mechanism may further include: a first spring including a first end and a second end, the first end of the first spring being connected to the first end of the guide block, and the second end of the first spring being fixed to the main body of the respiratory ventilation device; and a second spring including a first end and a second end, the first end of the second spring being connected to the second end of the guide block, and the second end of the second spring being fixed to the main body of the respiratory ventilation device; wherein, when the guide block is driven to move along the first direction, the first spring can be compressed; and the compressed first spring can drive the guide block to move in a direction opposite to the first direction.

[0148] In some embodiments, when driven by a first thrust, the push rod is capable of pushing the guide block to move in the first direction, while the push rod moves in the second direction and slides downward along the first inclined surface of the guide block; when the first thrust is released, the push rod is capable of moving in a direction opposite to the second direction, while the guide block moves in a direction opposite to the first direction, so that the push rod is stuck in the groove of the guide block; when driven by a second thrust, the push rod is capable of moving in the second direction and out of the groove, while the guide block moves in a direction opposite to the first direction, so that the push rod is released from the groove; and when the second thrust is released, the push rod is capable of moving in a direction opposite to the second direction and sliding upward along the second inclined surface of the guide block, while the guide block moves in a direction opposite to the first direction, so that the liquid chamber is released from the main body.

[0149] In some embodiments, the slider may further include a protrusion located below the groove of the guide block, wherein the protrusion is configured to guide the push rod to be clamped into the groove when the first thrust is released.

[0150] In some embodiments, the push rod may be disposed below the bottom surface of the liquid chamber; the guide groove and the slider may be disposed below the interface between the liquid chamber and the respiratory ventilation device body; the plate located on the interface may include a first hole; and the push rod may be able to pass through the first hole to interact with the slider.

[0151] In some embodiments, the plate located at the interface may include a second hole; the humidification assembly may also include a heating plate, which is configured to heat one or more liquids and generate steam to humidify the pressurized respiratory gas; and the heating plate may be mounted on the base of the respiratory ventilation device by one or more springs so that the heating plate can move up and down through the second hole when driven by pressure or when the pressure is released.

[0152] In some embodiments, the liquid chamber may include a bottom comprising a metallic thermally conductive material; and when the liquid chamber is mounted on the main body of the respiratory ventilation device, the bottom of the liquid chamber may be in close contact with the heating plate.

[0153] In some embodiments, the gas outlet may be disposed on a body of the respiratory ventilation device.

[0154] In some embodiments, the gas outlet may be provided on the liquid chamber.

[0155] In some embodiments, the push-push mechanism can be configured to unlock the liquid chamber from the main body of the respiratory ventilation device by pushing the liquid chamber in a direction substantially perpendicular to the liquid level in the liquid chamber. Because pushing is easier than pulling and can be performed one-handed, user comfort is improved. Furthermore, any locking and / or connecting mechanism between the liquid chamber and the main body will experience less pulling force and its lifespan is increased, as such mechanisms can generally withstand higher pushing forces than pulling forces. Furthermore, push-to-unlocking reduces the likelihood of liquid spilling from the housing during disassembly.

[0156] In some embodiments, the push-push mechanism can be configured to include an energy storage device for storing energy of the pushing action and for releasing the stored energy by applying a force on the liquid chamber in a direction substantially opposite to the pushing direction after the liquid chamber is unlocked.

[0157] In some embodiments, the liquid chamber may include: a housing; and a lid pivotally connected to the housing via a connection mechanism; wherein the lid can be configured to be closed by pushing in the pushing direction and / or configured to be opened by pulling in a direction substantially opposite to the pushing direction. Because the lid can be closed in the same direction, a single push action can simultaneously close the lid and connect the liquid chamber to the main body, thereby increasing comfort. When the lid opens in opposite directions, the chance of a user confusing opening the lid with removing the liquid chamber from the main body is minimized, thereby preventing a user from accidentally opening the lid and pouring out the liquid when they intended only to disconnect the humidifying assembly.

[0158] In some embodiments, a method for operating a respiratory ventilation device may include: connecting the humidification assembly to the main body of the respiratory ventilation device by pushing the liquid chamber in a pushing direction; and unlocking the humidification assembly from the main body by pushing the liquid chamber substantially in the pushing direction.

[0159] In some embodiments, the liquid chamber may include: a box body; and a box cover, which is pivotally connected to the box body by a connecting mechanism; the method may also include: before the connecting step, placing the humidification component on the surface of the respiratory ventilation device; the step of connecting the humidification component may also include locking the box cover with the box body by pushing the box cover basically along the pushing direction. BRIEF DESCRIPTION OF THE DRAWINGS

[0160] The present application is further described based on exemplary embodiments. These exemplary embodiments are described in detail with reference to the accompanying drawings. The drawings are not drawn to scale. These embodiments are non-limiting exemplary embodiments, in which like reference numerals represent similar structures throughout the several views of the drawings, and in which:

[0161] Figure 1 is a schematic diagram showing an exemplary system for delivering breathing gas according to some embodiments of the present disclosure;

[0162] Figure 2 is a block diagram showing an exemplary respiratory ventilation apparatus according to some embodiments of the present disclosure;

[0163] Figures 3A to 3D shows an exemplary respiratory ventilation device according to some embodiments of the present disclosure;

[0164] Figure 4 shows an exemplary process for delivering breathing gas according to some embodiments of the present disclosure;

[0165] Figures 5A to 5Eshows an exemplary gas channel of a respiratory ventilation device according to some embodiments of the present disclosure;

[0166] Figures 6A to 6E shows an exemplary gas filter component according to some embodiments of the present disclosure;

[0167] Figure 7A and Figure 7B shows an exemplary gas filtration unit according to some embodiments of the present disclosure;

[0168] Figures 8A to 8D shows different views of an exemplary noise reduction assembly according to some embodiments of the present disclosure;

[0169] Figures 9A to 9E shows an exemplary connection between a noise reduction assembly and a main body of a respiratory ventilation device according to some embodiments of the present disclosure;

[0170] Figures 10A to 10C shows an exploded view of an exemplary noise reduction assembly according to some embodiments of the present disclosure;

[0171] Figures 11A to 11F shows an exemplary connection between a gas pressure unit and a noise reduction box according to some embodiments of the present disclosure;

[0172] 12A to 12C shows an exemplary gas pressure unit according to some embodiments of the present disclosure;

[0173] Figure 13A and Figure 13B shows an exemplary connector according to some embodiments of the present disclosure;

[0174] Figure 14A and Figure 14B An exemplary respiratory ventilation device including a gas parameter detection assembly according to some embodiments of the present disclosure is shown;

[0175] Figure 15A and Figure 15B shows an interior space of an exemplary respiratory ventilation device including a gas parameter detection assembly according to some embodiments of the present disclosure;

[0176] 16A to 16D shows a portion of an exemplary gas parameter detection assembly and / or air flow detection assembly according to some embodiments of the present disclosure;

[0177] Figure 17 shows an exemplary respiratory ventilation device according to some embodiments of the present disclosure;

[0178] Figure 18A and Figure 18Bshows an exploded view of an exemplary liquid chamber according to some embodiments of the present disclosure;

[0179] Figure 19 shows an exemplary push-push mechanism connected to a liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure;

[0180] Figure 20A and Figure 20B shows an exemplary push-push mechanism according to some embodiments of the present disclosure;

[0181] Figure 21A and Figure 21B An exemplary process of installing a liquid chamber on a body of a respiratory ventilation device according to some embodiments of the present disclosure by a push-push mechanism is shown;

[0182] Figure 21C and Figure 21D shows an exemplary process of removing a liquid chamber from a body of a respiratory ventilation device according to some embodiments of the present disclosure via a push-push mechanism;

[0183] 22A to 22D shows an exemplary heating plate according to some embodiments of the present disclosure;

[0184] 23A to 23D shows an exemplary connection between a liquid chamber and a body of a respiratory ventilation device according to some embodiments of the present disclosure;

[0185] Figure 24 shows another exemplary connection between a liquid chamber and a body of a respiratory ventilation device according to some embodiments of the present disclosure;

[0186] Figure 25 shows an exemplary connector secured to a body of a respiratory ventilation device according to some embodiments of the present disclosure;

[0187] Figures 26A to 26C shows an exemplary connection between a liquid chamber and a body of a respiratory ventilation device according to some embodiments of the present disclosure;

[0188] Figure 27 An exemplary connection between a connector and a connecting plate of a box lid when the box lid is closed according to some embodiments of the present disclosure is shown;

[0189] Figures 28A to 28E An exemplary threaded hose showing a connector according to some embodiments of the present disclosure;

[0190] 29A to 29D shows an exemplary substrate of a respiratory ventilation device according to some embodiments of the present disclosure;

[0191] Figure 30A and Figure 30B shows an exemplary liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure;

[0192] Figure 31 An exemplary case cover for a liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure is shown;

[0193] Figures 32A to 32C An exemplary housing of a liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure is shown;

[0194] Figure 33A and Figure 33B shows an exemplary case according to some embodiments of the present disclosure;

[0195] Figure 34A and Figure 34B An exemplary tank lid according to some embodiments of the present disclosure is shown;

[0196] Figure 35A and Figure 35B The figure shows the cooperation between the protruding column of the first connecting member of the box body and the groove of the second connecting member of the box cover according to some embodiments of the present disclosure;

[0197] Figure 36A and Figure 36B shows an exemplary connection between a tank cover and a tank body of a liquid chamber according to some embodiments of the present disclosure;

[0198] Figure 37A and Figure 37B An exemplary tank lid according to some embodiments of the present disclosure is shown;

[0199] Figure 38 An exemplary cover shell according to some embodiments of the present disclosure is shown;

[0200] Figure 39A and Figure 39B shows an exemplary inner shell of a tank cover according to some embodiments of the present disclosure;

[0201] Figure 40 An exemplary bottom plate of an inner shell of a tank cover according to some embodiments of the present disclosure is shown;

[0202] Figure 41A and Figure 41B shows an exemplary internal structure of an inner shell of a case cover according to some embodiments of the present disclosure;

[0203] Figure 42A and Figure 42B Another exemplary tank lid according to some embodiments of the present disclosure is shown;

[0204] Figures 43A to 43C shows exemplary electronic components in the body of a respiratory ventilation device according to some embodiments of the present disclosure;

[0205] Figure 44A and Figure 44B shows an exemplary heating device according to some embodiments of the present disclosure; and

[0206] Figure 45 An exemplary liquid chamber according to some embodiments of the present disclosure is shown. DETAILED DESCRIPTION

[0207] The following description is presented to enable one skilled in the art to make and use the present application and is provided in the context of a particular application and its requirements. Various modifications to the disclosed embodiments will be apparent to those skilled in the art, and the general principles defined herein may be applied to other embodiments and applications without departing from the spirit and scope of the present application. Therefore, the disclosure of the present application is not limited to the embodiments shown, but is to be construed in accordance with the broadest scope of the claims.

[0208] The terms used herein are intended only to describe specific exemplary embodiments and are not intended to be limiting. As used herein, the singular forms "a," "an," and "the" may include plural forms unless the context clearly indicates otherwise. It should be further understood that the terms "include" and / or "comprise" used in this application specify the features, integers, steps, operations, elements, and / or components described, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups.

[0209] These and other features of the present application, as well as the operation and function of the related elements of the structure, as well as the combination of parts and manufacturing economy, may become more apparent upon consideration of the following description. Reference is made to the accompanying drawings, all of which form a part of this application. However, it should be expressly understood that the drawings are for illustration and description purposes only and are not intended to limit the scope of the present application. It should be understood that the drawings are not drawn to scale.

[0210] It should be understood that the terms "system," "engine," "unit," and / or "module" used herein are a method of distinguishing different components, elements, parts, portions, or assemblies at different levels. However, these terms may be replaced by other expressions if they achieve the same purpose.

[0211] It should be understood that when a unit, engine, or module is referred to as being "connected," "connected to," or "coupled to" another unit, engine, or module, it can be directly connected, unless the context clearly indicates otherwise, or there can be intermediate units, engines, or modules connected or coupled to or in communication with the other unit, engine, or module. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0212] As used herein, the term "environment" refers to the environment outside of, or surrounding, system 100 and / or subject 180. As used herein, "ambient gas" may refer to the gas outside of, or surrounding, system 100 and / or subject 180. The term "ambient humidity" with respect to a humidifier may refer to the humidity of the gas surrounding the humidifier (e.g., the humidity of the room in which respiratory ventilation device 110 and / or subject 180 is located). The term "ambient pressure" may refer to the pressure surrounding or outside of subject 180. The term "ambient (e.g., acoustic) noise" may refer to the background noise level in, for example, respiratory ventilation device 110 and / or the room in which respiratory ventilation device 110 is located, in addition to, for example, noise generated by respiratory ventilation device 110 or noise emanating from subject interface 170.

[0213] The flowcharts used in this application illustrate the operations of a system implementation according to some embodiments of the present application. It should be clearly understood that the operations of the flowcharts may not be implemented in order. Instead, the operations may be implemented in reverse order or simultaneously. In addition, one or more other operations may be added to the flowcharts. One or more operations may be omitted from the flowcharts.

[0214] Figure 1 is a schematic diagram illustrating an exemplary system for delivering breathing gas according to some embodiments of the present application. In some embodiments, the breathing gas may include natural air (or atmospheric air), purified air, oxygen, oxygen-enriched atmosphere, therapeutic drugs, pressurized air, humidified air, etc., or a combination thereof. As shown, the system 100 may include a respiratory ventilation device 110, a breathing tube 160, and an object interface 170. In some embodiments, the respiratory ventilation device may be a non-invasive ventilator. In some embodiments, the system 100 may also include a network 120, a terminal 130, a processing device 140, and a storage device 150. It should be noted that one or more of the network 120, the terminal 130, the processing device 140, and the storage device 150 may be omitted. The components in the system 100 may be connected in one or more of various ways. As an example only, Figure 1As shown, respiratory ventilation device 110 can be connected to processing device 140 via network 120. As another example, respiratory ventilation device 110 can be directly connected to processing device 140, as indicated by a double-headed arrow in the dashed line connecting respiratory ventilation device 110 and processing device 140. As another example, storage device 150 can be connected to processing device 140 directly or via network 120. As yet another example, terminal 130 can be directly connected to processing device 140 (as indicated by a double-headed arrow in the dashed line connecting terminal 130 and processing device 140) or connected to processing device 140 via network 120. In this application, "respiratory ventilation device" and "continuous positive airway pressure (CPAP) device" are used interchangeably.

[0215] Respiratory ventilation device 110 may be configured to detect, diagnose, treat, prevent, and / or improve a respiratory-related condition of subject 180. In some embodiments, respiratory ventilation device 110 may deliver pressurized respiratory gas to subject 180 (e.g., the nose and / or mouth of subject 180). In some embodiments, respiratory ventilation device 110 may include a gas inlet 112 and a gas outlet 111. Gas inlet 112 may be configured to introduce respiratory gas into respiratory ventilation device 110. In some embodiments, respiratory ventilation device 110 may pressurize the respiratory gas introduced through gas inlet 112. In some embodiments, gas outlet 111 may be connected to breathing tube 160. Gas outlet 111 may be configured to exhaust the pressurized respiratory gas. In some embodiments, breathing tube 160 may be connected to subject interface 170. Thus, the pressurized respiratory gas generated by respiratory ventilation device 110 may be exhausted to subject 180 via breathing tube 160 and subject interface. In some embodiments, respiratory ventilation device 110 may include one or more gas channels ( Figure 1 ), the gas passage is configured to guide the breathing gas to flow in the respiratory ventilation device 110. Further description of the respiratory ventilation device 110 can be found elsewhere in this application (e.g., Figures 3A-3D as well as Figures 5A-5E and its description).

[0216] In some embodiments, the respiratory ventilation device 110 may further include one or more controllers. The controllers may be connected to one or more components of the respiratory ventilation device directly or via a network (e.g., a wired network, a wireless network). The controllers may control the operation of one or more components of the respiratory ventilation device. In some embodiments, the controllers may be configured to activate the respiratory ventilation device 110 during boot operation. For example, the controllers may activate a random access memory (RAM) of the respiratory ventilation device 110, read one or more parameters from one or more storage devices 150 (e.g., non-volatile memory) of the respiratory ventilation device 110, and / or activate the detection module 250. In some embodiments, the parameters may include at least one parameter for controlling the pressure of the pressurized respiratory gas. In some embodiments, the controllers may be configured to activate a program that continuously reads information from the detection module 250 and uses at least the information read from the detection module 250 and the one or more parameters to control the pressure of the pressurized respiratory gas.

[0217] In some embodiments, respiratory ventilation device 110 may further include or be equipped with one or more sensors configured to detect parameters related to respiratory gas, exhaled gas from subject 180, and / or the operating state of respiratory ventilation device 110. Parameters related to respiratory gas may include, for example, the flow rate of respiratory gas, the flow velocity of respiratory gas, the temperature of respiratory gas, the humidity of respiratory gas, or the like, or a combination thereof. Parameters related to exhaled gas from subject 180 may include snoring of subject 180, respiratory rate of subject 180, respiratory volume of subject 180, pressure of exhaled gas from subject 180, deflated volume of exhaled gas from subject 180, spontaneous breathing rate of subject 180, or the like, or a combination thereof. Parameters related to the operating state of respiratory ventilation device 110 may include the operating time of respiratory ventilation device 110, the delay time of pressurized respiratory gas, deflated volume of pressurized respiratory gas, input voltage of gas pressurizing unit 210, or the like, or a combination thereof.

[0218] In some embodiments, respiratory ventilation device 110 may further include or be equipped with one or more gas filtration units configured to filter and / or purify the respiratory gas delivered to subject 180. In some embodiments, the gas filtration unit (e.g., a coarse filter, a fine filter, etc.) may filter one or more particles from the respiratory gas. In some embodiments, the gas filtration unit may filter bacteria from the respiratory gas. In some embodiments, the gas filtration unit may filter irritants from the respiratory gas.

[0219] In some embodiments, the subject 180 may be a healthy person. In some embodiments, the subject 180 may be a patient. In some embodiments, the patient may suffer from one or more respiratory-related disorders. In some embodiments, the respiratory-related disorders may be characterized by apnea, hypopnea, or hyperpnea, etc. Exemplary respiratory-related disorders may include, for example, obstructive sleep apnea (OSA), Cheyne-Stokes respiration (CSR), obesity hyperventilation syndrome (OHS), chronic obstructive pulmonary disease (COPD), neuromuscular disease (NMD), chest wall disease, etc. Obstructive sleep apnea (OSA) is a form of sleep-disordered breathing and may cause the affected patient to stop breathing for one or more periods (e.g., for 30 to 120 seconds, or 200 to 300 times per night). Cheyne-Stokes respiration (CSR) is another form of sleep-disordered breathing and may be harmful due to repetitive hypoxia. Obesity hyperventilation syndrome (OHS) is defined as a combination of severe obesity and chronic hypercapnia during wakefulness, and may cause dyspnea, morning headaches, excessive daytime sleepiness, etc. Chronic obstructive pulmonary disease (COPD) may include increased resistance to air movement, a prolonged expiratory phase of breathing, or loss of normal elasticity of the lungs. Chronic obstructive pulmonary disease (COPD) may cause dyspnea on exertion, chronic cough, sputum production, etc. Neuromuscular diseases (NMD) may include diseases and disorders that impair muscle function directly through intrinsic muscle pathology or indirectly through neuropathology. Neuromuscular diseases (NMD) may cause generalized weakness, dysphagia, dyspnea during exercise and at rest, fatigue, drowsiness, morning headaches, difficulty concentrating, and mood changes. Chest wall disease is a group of chest deformities that result in inefficient coupling between the respiratory muscles and the thorax. Chest wall disease may cause dyspnea on exertion, peripheral edema, orthopnea, recurrent chest infections, morning headaches, fatigue, poor sleep quality, loss of appetite, etc.

[0220] In some embodiments, subject interface 170 can be configured to connect respiratory ventilation device 110 to subject 180, for example, by providing a flow of breathing gas (e.g., air). In some embodiments, subject interface 170 can include a gas passageway for directing breathing gas. Subject connection device 170 can include a mask, a tube, or the like. For example, subject connection device 170 can be a nasal mask, a full-face mask, a tube connected to the mouth of subject 180, or a tracheostomy tube connected to the trachea of ​​subject 180. In some embodiments, subject connection device 170 can form a sealed connection with a facial area of ​​subject 180 to facilitate delivery of breathing gas at a pressure sufficient to vary from ambient pressure to achieve therapy (e.g., a positive pressure of approximately 10 cmH2O). For example, subject connection device 170 can be secured to the nose of subject 180 using various securing means (e.g., a securing cord or a securing ring). In some embodiments, subject connection device 170 may not form a sealed connection with a facial area of ​​subject 180 sufficient to facilitate delivery of breathing gas to subject 180 at a positive pressure of approximately 10 cmH2O. In some embodiments, the subject connection device 170 may further include a filter configured to filter respiratory gases. Further description of filters can be found elsewhere in this application (e.g., Figures 6A-6E , 7A and 7B and their descriptions). In some embodiments, subject connection device 170 may further include or be equipped with one or more sensors configured to detect parameters related to the respiratory gas and / or exhaled gas of subject 180. In some embodiments, subject connection device 170 may also include or be equipped with one or more gas filtration units configured to filter and / or purify the respiratory gas delivered to subject 180. In some embodiments, the gas filtration unit (e.g., a coarse filter, a fine filter, etc.) may filter one or more particles in the respiratory gas. In some embodiments, the gas filtration unit may filter bacteria in the respiratory gas. In some embodiments, the gas filtration unit may filter irritating gases in the respiratory gas.

[0221] In some embodiments, breathing tube 160 can be configured to direct breathing gas from respiratory ventilation device 110 to subject connection device 170. Breathing tube 160 can include a gas channel for directing breathing gas. In some embodiments, breathing tube 160 can form a sealed connection with gas outlet 111 of respiratory ventilation device 110. In some embodiments, breathing tube 160 can form a sealed connection with subject connection device 170. In some embodiments, breathing tube 160 can further include a heater configured to heat breathing tube 160 so that the breathing gas flowing through breathing tube 160 can be maintained at a specific temperature, preferably a temperature comfortable for the human body, such as a temperature within a range of 16-43°C, or within a range of 28-38°C. In some embodiments, breathing tube 160 can further include or be equipped with one or more sensors configured to detect parameters related to respiratory gas and / or exhaled gas of subject 180. In some embodiments, breathing tube 160 can further include or be equipped with one or more gas filtration units configured to filter and / or purify the breathing gas delivered to subject 180. In some embodiments, the gas filtration unit (e.g., a coarse filter, a fine filter, etc.) can filter one or more particles from the respiratory gas. In some embodiments, the gas filtration unit can filter bacteria from the respiratory gas. In some embodiments, the gas filtration unit can filter irritants from the respiratory gas.

[0222] In some embodiments, network 120 may comprise any suitable network that facilitates information and / or data exchange between system 100. In some embodiments, one or more components of system 100 (e.g., respiratory device 110, terminal 130, processing device 140, or storage device 150) may communicate information and / or data with one or more other components of system 100 via network 120. For example, processing device 140 may receive a signal from respiratory device 110 via network 120. As another example, processing device 140 may receive a user instruction from terminal 130 via network 120. In some embodiments, network 120 may be any type of wired or wireless network, or a combination thereof. The network 120 may be and / or include a public network (e.g., the Internet), a private network (e.g., a local area network (LAN), a wide area network (WAN), etc.), a wired network (e.g., an Ethernet network), a wireless network (e.g., an 802.11 network, a Wi-Fi network, etc.), a cellular network (e.g., a Long Term Evolution (LTE) network), a frame relay network, a virtual private network (“VPN”), a satellite network, a telephone network, a router, a hub, a switch, a server computer, and / or any combination thereof. By way of example only, the network 120 may include a cable network, a wired network, a fiber optic network, a telecommunications network, an intranet, a wireless local area network (WLAN), a metropolitan area network (MAN), a public switched telephone network (PSTN), a Bluetooth network, a ZigBee™ network, a near field communication (NFC) network, etc., or any combination thereof. In some embodiments, the network 120 may include one or more network access points. For example, the network 120 may include wired and / or wireless network access points, such as base stations and / or Internet exchange points, through which one or more components of the system 100 may connect to the network 120 to exchange data and / or information.

[0223] In some embodiments, terminal 130 may include a mobile device 130-1, a tablet computer 130-2, a laptop computer 130-3, or the like, or any combination thereof. In some embodiments, mobile device 130-1 may include a smart home device, a wearable device, a smart mobile device, a virtual reality device, an augmented reality device, or the like, or any combination thereof. In some embodiments, smart home devices may include smart lighting devices, smart appliance control devices, smart monitoring devices, smart cameras, intercoms, or the like, or any combination thereof. In some embodiments, wearable devices may include smart bracelets, smart shoes and socks, a pair of smart glasses, a smart helmet, a smart watch, smart clothing, a smart backpack, smart accessories, or the like, or any combination thereof. In some embodiments, smart mobile devices may include smartphones, personal digital assistants (PDAs), gaming devices, navigation devices, point-of-sale (POS) devices, or the like, or any combination thereof. In some embodiments, virtual reality devices and / or augmented reality devices may include virtual reality helmets, virtual reality glasses, virtual reality patches, augmented reality helmets, augmented reality glasses, augmented reality patches, or the like, or any combination thereof. For example, virtual reality devices and / or augmented reality devices may include Google Glass, head-mounted displays, holographic glasses, virtual reality helmets, or the like. In some embodiments, terminal 130 can remotely operate respiratory ventilation device 110. In some embodiments, terminal 130 can operate respiratory ventilation device 110 via a wireless connection. In some embodiments, terminal 130 can receive information and / or instructions input by a user and transmit the received information and / or instructions to respiratory ventilation device 110 or processing device 140 via network 120. In some embodiments, terminal 130 can receive data and / or information from processing device 140. In some embodiments, terminal 130 can display information related to system 100. In some embodiments, terminal 130 can be part of processing device 140. In some embodiments, terminal 130 can be omitted. In some embodiments, a user can remotely update the software of respiratory ventilation device 110 and / or set one or more parameters of respiratory ventilation device 110 through terminal 130.

[0224] In some embodiments, processing device 140 can process data and / or information obtained from respiratory ventilation device 110, terminal 130, and / or storage device 150. For example, processing device 140 can obtain signals detected by one or more sensors in respiratory ventilation device 110, breathing tube 160, and / or subject interface 170, and can process and / or analyze the signals to obtain one or more parameters related to subject 180's respiratory gases, exhaled gases, and / or the operating state of respiratory ventilation device 110. In some embodiments, processing device 140 can be a single server or a server group. The server group can be centralized or distributed. In some embodiments, processing device 140 can be local or remote. For example, processing device 140 can access information and / or data stored in respiratory ventilation device 110, terminal 130, and / or storage device 150 via network 120. As another example, processing device 140 can be directly connected to respiratory ventilation device 110, terminal 130, and / or storage device 150 to access the stored information and / or data. In some embodiments, processing device 140 can be implemented on a cloud platform. By way of example only, the cloud platform may include a private cloud, a public cloud, a hybrid cloud, a community cloud, a distributed cloud, an inter-cloud cloud, a multi-cloud, etc., or any combination thereof. In some embodiments, the processing device 140 may be implemented on a computing device of the respiratory ventilation device 110 .

[0225] In some embodiments, the processing device 140 may include an acquisition unit and a processing unit. The acquisition unit may be configured to obtain information related to the system 100 (e.g., the respiratory ventilation device 110, the processing device 140, the storage device 150, the terminal 130, etc.). This information may include signals detected by the detection module 250, data read from the storage device 150, instructions or data provided by the terminal 130, etc. In some embodiments, the information may be sent to the processing unit for processing. In some embodiments, the acquisition unit may obtain or transmit information via a tangible transmission medium or a carrier transmission medium. Tangible transmission media may include, for example, coaxial cables, copper wires, optical fibers, etc. The carrier transmission medium may take the form of electrical signals or electromagnetic signals (e.g., signals generated during radio frequency (RF) data communication). The processing unit may be configured to process the information obtained by the acquisition unit. The processing unit may include an advanced RISC machine processor (ARM), a programmable logic device (PLD), a microprocessor (MCU), a digital signal processor (DSP), a field programmable gate array (FPGA), a system-on-chip (SoC), etc., or any combination thereof.

[0226] In some embodiments, storage device 150 may store data and / or instructions. In some embodiments, storage device 150 may store data or information obtained from respiratory ventilation device 110. For example, based on signals obtained from one or more sensors of respiratory ventilation device 110, breathing tube 160, and / or subject connection device 170, processing device 140 may determine one or more parameters related to respiratory gases, exhaled gases of subject 180, and / or the operating state of respiratory ventilation device 110. The determined parameters may be stored in storage device 150 for further use or processing. In some embodiments, storage device 150 may store data obtained from terminal 130 and / or processing device 140. In some embodiments, storage device 150 may store data and / or instructions that processing device 140 may execute or use for executing the exemplary methods described herein. In some embodiments, storage device 150 may include a mass storage device, a removable storage device, a volatile read-write memory, a read-only memory (ROM), or the like, or any combination thereof. Exemplary mass storage devices may include magnetic disks, optical disks, solid-state drives, and the like. Exemplary removable memory may include a flash drive, a floppy disk, an optical disk, a memory card, a zipper disk, or a magnetic tape, and exemplary volatile read-write memory may include random access memory (RAM). Exemplary RAM may include dynamic RAM (DRAM), double data rate synchronous dynamic RAM (DDR SDRAM), static RAM (SRAM), thyristor RAM (T-RAM), and zero capacitor RAM (Z-RAM). Exemplary ROM may include mask ROM (MROM), programmable ROM (PROM), erasable programmable ROM (PEROM), electrically erasable programmable ROM (EEPROM), compact disc ROM (CD-ROM), and digital versatile disc ROM, among others. In some embodiments, storage device 150 may be implemented on a cloud platform. By way of example only, a cloud platform may include a private cloud, a public cloud, a hybrid cloud, a community cloud, a distributed cloud, an inter-cloud cloud, a multi-cloud, or any combination thereof.

[0227] In some embodiments, storage device 150 can be connected to network 120 to communicate with one or more components in system 100 (e.g., respiratory ventilation device 110, processing device 140, terminal 130, etc.). One or more components in system 100 can access data or instructions stored in storage device 150 via network 120. In some embodiments, storage device 150 can be directly connected to or communicate with one or more components in system 100 (e.g., respiratory ventilation device 110, processing device 140, terminal 130, etc.). In some embodiments, storage device 150 can be part of processing device 140. In some embodiments, storage device 150 can be part of respiratory ventilation device 110.

[0228] Figure 2 FIG is a block diagram illustrating an exemplary respiratory ventilation device 110 according to some embodiments of the present application. Figure 2 As shown, respiratory ventilation device 110 may include a pressurized air (CPAP) unit 210 , a humidification assembly 220 , an air filtration component 230 , a noise reduction assembly 240 , a detection module 250 , a control module 260 , and one or more peripheral devices 270 .

[0229] Gas pressurizing unit 210 can be configured to pressurize the breathing gas introduced into respiratory ventilation device 110. In some embodiments, gas pressurizing unit 210 can generate pressurized breathing gas based on introduced ambient gas (e.g., atmospheric air). In some embodiments, gas pressurizing unit 210 can provide pressurized breathing gas to subject 180. In some embodiments, gas pressurizing unit 210 can include a blower (e.g., a motor-driven blower). In some embodiments, gas pressurizing unit 210 can include a compressed gas reservoir. In some embodiments, when the blower is operating, breathing gas (e.g., ambient gas) can be continuously drawn into respiratory ventilation device 110 via gas inlet 112, and the breathing gas can then be pressurized. The pressurized breathing gas generated by gas pressurizing unit 210 can be further discharged into breathing tube 160 via gas outlet 111. In some embodiments, gas pressurizing unit 210 can be controlled by a controller of respiratory ventilation device 110. For example, the activation, operation (e.g., speed), and / or deactivation of gas pressurizing unit 210 can be controlled (and / or regulated) by the controller of respiratory ventilation device 110.

[0230] Humidification assembly 220 can be configured to humidify (pressurized) respiratory gases. In some embodiments, humidification assembly 220 can humidify (pressurized) respiratory gases by introducing water vapor into the (pressurized) respiratory gases. In some embodiments, humidification assembly 220 can include a liquid chamber 222 and / or a heating device 224. Liquid chamber 222 can be configured to hold one or more liquids (e.g., water). Heating device 224 can be configured to heat the one or more liquids contained in liquid chamber 222 and / or generate water vapor having a temperature in the range of, for example, 30-50 degrees Celsius. Water vapor can be introduced into the (pressurized) respiratory gases, which can then be humidified. In some embodiments, liquid chamber 222 can include a box and / or a box lid. The box can be configured to hold one or more liquids. The box lid can be configured to introduce (pressurized) respiratory gases onto the surface of the one or more liquids and / or to introduce humidified (pressurized) respiratory gases into liquid chamber 222. In some embodiments, the case cover may include a housing, a gas inlet configured to introduce (pressurized) breathing gas into the liquid chamber 222 via a first gas passage, and / or a gas outlet configured to introduce humidified (pressurized) breathing gas back into the respiratory ventilation device 110 via a second gas passage. In some embodiments, the heating device 224 may include a heater plate mounted below the case or the interior floor of the case, one or more heating rods, one or more heating electrodes, the like, or any combination thereof.

[0231] In some embodiments, the humidification assembly 220 can humidify the (pressurized) respiratory gas by introducing one or more water droplets into the (pressurized) respiratory gas. In some embodiments, the humidification assembly 220 can include a liquid chamber 222 not shown and / or an ultrasonic nebulizer (e.g., a ceramic diaphragm). The ceramic diaphragm can be controlled by a controller of the respiratory ventilation device 110 to vibrate at an ultrasonic frequency to produce a plurality of water droplets. The water droplets can be introduced into the (pressurized) respiratory gas, which can then be humidified. Further description of the humidification assembly 220 can be found elsewhere in this application (e.g., Figure 17-2 2, Figures 30A-36B and its description).

[0232] Gas filtering component 230 can be configured to filter respiratory gas introduced into respiratory ventilation device 110. In some embodiments, gas filtering component 230 can filter pressurized respiratory gas discharged from gas pressurizing unit 210. In some embodiments, gas filtering component 230 can include a housing. In some embodiments, the housing of gas filtering component 230 can be removably connected to gas inlet 112 of respiratory ventilation device 110. In some embodiments, gas filtering component 230 can include multiple gas filtering units. In some embodiments, one or more gas filtering units can be mounted in the housing. In some embodiments, one or more gas filtering units can be mounted anywhere else on respiratory ventilation device 110, breathing tube 160, and / or subject connection device 170. In some embodiments, one or more of the one or more gas filtering units can be configured to filter respiratory gas entering respiratory ventilation device 110. In some embodiments, one or more gas filtering units can be configured to filter respiratory gas entering CPAP. In some embodiments, one or more gas filtering units can be configured to filter pressurized respiratory gas flowing out of gas pressurizing unit 210. In some embodiments, one or more gas filtering units can be configured to filter pressurized respiratory gas flowing into humidification assembly 220. In some embodiments, one or more gas filter units may be configured to filter the humidified and pressurized respiratory gas flowing from humidification assembly 220 .

[0233] In some embodiments, the gas filter component 230 may include one or more ultrafine filter units installed on the outside of the gas inlet 112, one or more gas filter units installed on the inside of the gas inlet 112, one or more gas filter units with an antibacterial membrane or a deodorizing membrane, and one or more gas filter units with an antibacterial membrane or a deodorizing membrane are located in the gas channel of the respiratory ventilation device 110, the breathing tube 160 and / or the object connection device 170.

[0234] By way of example only, in some embodiments, the gas filter component 230 may include a first gas filter unit. The first gas filter unit may be a coarse filter. In some embodiments, the gas filter component 230 may include a second gas filter unit. The second gas filter unit may be a fine filter. In some embodiments, the gas filter component 230 may include a third gas filter unit. The third gas filter unit may be mounted within the gas inlet 112 of the respiratory ventilation device 110. The third gas filter unit may be configured to filter ambient gas entering the respiratory ventilation device 110. In some embodiments, the third gas filter unit may include a coarse filter and / or a fine filter. In some embodiments, the gas filter component 230 may include a fourth gas filter unit. The fourth gas filter unit may be configured to filter one or more gases with a pungent odor (also referred to as irritant gases) in one or more gas passages of the respiratory ventilation device 110. In some embodiments, the fourth gas filter unit may include a membrane made of one or more nanomaterials having adsorptive properties (e.g., activated carbon, graphene, etc.). In some embodiments, the gas filter component 230 may include a fifth gas filter unit. The fifth gas filter unit can be configured to filter bacteria from one or more gases in one or more gas passages of the respiratory ventilation device 110, the breathing tube 160, and / or the subject connection device 170. Further description of the gas filter component 230 can be found elsewhere in this application (e.g., Figures 6A-7B and its description).

[0235] The noise reduction assembly 240 can be configured to reduce the noise generated by the operation of the gas pressurization unit 210 (e.g., a blower) and / or the flow of breathing gas. In some embodiments, the noise reduction assembly 240 may include a noise reduction box that houses the gas pressurization unit 210. In some embodiments, the noise reduction box may include one or more sound absorbing materials disposed on the inner wall of the noise reduction box. In some embodiments, the noise reduction box may include one or more frames configured to secure one or more sound absorbing materials. Exemplary sound absorbing materials may include organic fibers, inorganic fibers, inorganic foams, foam plastics, etc., or any other material having a sound absorbing function. Further description of the noise reduction assembly 240 may be found elsewhere in this application (e.g., Figures 8A-11F and its description).

[0236] Detection module 250 may be configured to detect one or more parameters related to system 100 (e.g., respiratory ventilation device 110, subject 180). Exemplary parameters may include a flow rate of respiratory gas, a flow rate of respiratory gas, a temperature of respiratory gas, a humidity of respiratory gas, snoring of subject 180, a respiratory rate of subject 180, a respiratory volume of subject 180, or the like, or a combination thereof. In some embodiments, the parameters may include an operating state of respiratory ventilation device 110 (e.g., an operating time of respiratory ventilation device 110, a delay time for pressurizing respiratory gas, an amount of air leakage of pressurized respiratory gas, an input voltage of gas pressurizing unit 210, or the like).

[0237] In some embodiments, the detection module 250 may include one or more sensors configured to detect parameters. Exemplary sensors may include flow sensors, pressure sensors, humidity sensors, temperature sensors, timers, etc. For example, the detection module 250 may include a snoring detection component (e.g., a pressure sensor) (see Figure 15A and 15B ), the snore detection component is configured to detect snoring of a user (eg, subject 180) of respiratory ventilation device 110. As another example, detection module 250 may include a flow detection component (see Figure 15A and 15B ), the flow detection component is configured to detect the flow of one or more gases in one or more channels of the respiratory ventilation device 110. In some embodiments, the detection module 250 may further include a liquid level detection component (e.g., a liquid level sensor) configured to detect the liquid level in the tank of the liquid cavity 222.

[0238] The control module 260 can be configured to control the operation of components of the system 100 (e.g., the gas pressurization unit 210, the humidification assembly 220, the gas filtration component 230, the detection module 250, the processing device 140, the storage device 150, the terminal 130, etc.). In some embodiments, the control module 260 can be configured to activate the respiratory ventilation device 110 during a boot operation. For example, the control module 260 can load a boot program from the storage device 150, load a user program from the storage device 150, activate one or more peripheral devices of the control module 260 (e.g., a communication interface, a timer, an AD acquisition interface, an indicator light, a button, a knob, a power switch, etc.), activate one or more sensors, activate the gas pressurization unit 210, activate one or more configuration parameters, and / or activate one or more processing parameters. As another example, the control module 260 can activate a random access memory of the respiratory ventilation device 110, read one or more parameters from the storage device 150 (e.g., a non-volatile memory) of the respiratory ventilation device 110, and / or activate the detection module 250. In some embodiments, control module 260 can be configured to initiate a program that continuously reads information from detection module 250 and uses at least the information read from the detection module and one or more parameters to control the pressure of the pressurized respiratory gas. In some embodiments, control module 260 can cause a sensor to detect one or more parameters (e.g., pressure) of the pressurized respiratory gas and / or adjust the rotational speed of gas pressurization unit 210 to maintain the detected pressure of the pressurized respiratory gas within a predetermined range. In some embodiments, in response to an abnormal condition determined based on a comparison between the current state of respiratory ventilation device 110 and a plurality of parameters read from storage device 150, control module 260 can cause respiratory ventilation device 110 to issue an alarm or reminder to the user. In some embodiments, the current state of respiratory ventilation device 110 may include the pressure of the respiratory gas. In some embodiments, the parameters read from storage device 150 may include one or more thresholds associated with an upper limit for pressure, an upper limit for air leakage of the pressurized respiratory gas, a lower limit for air leakage of the pressurized respiratory gas, a lower limit for respiratory rate, or a lower limit for input voltage to respiratory ventilation device 110. In some embodiments, control module 260 may adjust the rotational speed of gas pressurizing unit 210 to delay pressurizing breathing gas after respiratory ventilation device 110 is activated.

[0239] The control module 260 can be implemented as a software and / or hardware module (e.g., a controller) and can be stored in any type of non-transitory computer-readable medium or other storage device. For example, the control module 260 can be stored in the processing device 140. In some embodiments, the software module can be compiled and linked into an executable program. It should be understood that the software modules can be called from other modules or from themselves, and / or can be called in response to detected events or interrupts. Software modules configured to be executed on a computing device (e.g., the processor of the processing device 140) can be provided on a computer-readable medium, such as a compact disc, digital video disc, flash drive, disk, or any other tangible medium, or as a digital download (and can initially be stored in a compressed or installable format, requiring installation, decompression, or decryption before execution). Such software code can be stored in part or in full on a memory device of the executing computing device for execution by the computing device. The software instructions can be embedded in firmware, such as an EPROM. It should also be understood that the hardware module can include connected logic units, such as gates and flip-flops, and / or can include programmable units, such as a programmable gate array or processor. The modules or computing device functions described herein can be implemented as software modules and can be represented in hardware or firmware. Generally, the modules described herein refer to logical modules, which can be combined with other modules or divided into sub-modules, regardless of the physical organization or storage of the logical modules. In some embodiments, the control module 260 or controller can include signal processing circuitry, memory circuitry, one or more processors, a single-chip microcomputer, etc., or a combination thereof. In some embodiments, at least a portion of the control module 260 or controller can be integrated into one or more printed circuit boards of the respiratory ventilation device 110.

[0240] The peripheral device 270 may be configured to facilitate operation or use of the respiratory ventilation device 110. In some embodiments, the peripheral device 270 may include the breathing tube 160, the subject connection device 170, etc., or a combination thereof. Further description of the peripheral device 270 may be found elsewhere in this application (e.g., Figure 1 and its description).

[0241] It should be noted that the above description of the respiratory ventilation device 110 is provided for illustrative purposes only and is not intended to limit the scope of the present application. A person skilled in the art may make various changes and modifications based on the teachings of the present application. However, those changes and modifications do not depart from the scope of the present application.

[0242] In some embodiments, respiratory ventilation apparatus 110 may include one or more additional modules, units, components, devices, etc.

[0243] For example, respiratory ventilation device 110 may include a storage module configured to store data generated during operation of respiratory ventilation device 110 .

[0244] As another example, respiratory ventilation device 110 may include one or more ultraviolet lamps disposed in one or more gas passages of respiratory ventilation device 110, breathing tube 160, and / or subject connection device 170. The ultraviolet lamps may be configured to disinfect one or more gases flowing in respiratory ventilation device 110, one or more gas passages in respiratory ventilation device 110, or one or more components of respiratory ventilation device 110 (e.g., humidification assembly 220), among other things.

[0245] As another example, respiratory ventilation device 110 may include one or more display panels configured to display information related to system 100 .

[0246] As another example, the respiratory ventilation device 110 may include a communication module that is configured to communicate information with the processing device 140, the terminal 130, etc. The communication module can be connected to a network (e.g., the network 120) to facilitate data communication. The communication module can establish a connection between the processing device 140 and the respiratory ventilation device 110, the terminal 130, or the storage device 150. The connection can be a wired connection, a wireless connection, or a combination of the two to enable data transmission and reception. The wired connection may include an electrical cable, an optical cable, a telephone line, etc., or any combination thereof. The wireless connection may include Bluetooth, Wi-Fi, a wireless metropolitan area network, a wireless local area network, a wireless personal area network, a mobile network (e.g., 3G, 4G, 5G, etc.), etc., or a combination thereof. In some embodiments, the communication module may include a standardized communication port, such as RS232, RS485, etc. In some embodiments, the communication module may include a specially designed communication port.

[0247] As another example, respiratory ventilation device 110 may include a remote control unit. The remote control unit may be configured to remotely operate respiratory ventilation device 110. A user (e.g., subject 180) may operate respiratory ventilation device 110 via the remote control unit without having to adjust one or more components of respiratory ventilation device 110 (e.g., switch 311, display panel 312, knob 313, home button 314, etc., as shown in FIG. 3 ).

[0248] In some embodiments, one or more components of respiratory ventilation device 110 may be omitted. For example, heating device 224 may be omitted and / or replaced with an ultrasonic nebulizer. As another example, humidification assembly 220 may be omitted. As another example, gas filtering component 230 may be omitted.

[0249] Figures 3A-3DAn exemplary respiratory ventilation apparatus according to some embodiments of the present application is shown. Figure 3A The front side of respiratory ventilator 300 is shown. Figure 3B The back side of respiratory ventilator 300 is shown. Figure 3C The other rear side of respiratory ventilator 300 is shown. Figure 3D The main components of the respiratory ventilation device 300 are shown. Figures 3A-3D As shown, respiratory ventilation device 300 may include a body 310 and a fluid chamber 320 .

[0250] like Figure 3A As shown, the main body 310 of the respiratory ventilation device 300 may include an on / off key 311, a display panel 312, a knob 313, a home button 314, etc. The on / off key 311 can be configured to switch the respiratory ventilation device 300 between an on state and an off state. For example, if the respiratory ventilation device 300 is off, the user (e.g., subject 180) can press the on / off key 311 to start the respiratory ventilation device 300. As another example, if the respiratory ventilation device 300 is on, the user (e.g., subject 180) can press the on / off key 311 to turn off the respiratory ventilation device 300. The display panel 312 can be configured to display information related to the respiratory ventilation device 300. The displayed information may include, for example, parameters related to respiratory gas, exhaled gas of subject 180, and / or the operating status of the respiratory ventilation device 110. More descriptions of the parameters can be found elsewhere in this application (e.g., Figure 1 In some embodiments, the display panel 312 can be configured as a software interface for the respiratory ventilation device 110. In the following embodiments, the display panel 312 can be a touch panel.

[0251] Knob 313 can be configured to facilitate a user (e.g., subject 180) adjusting and / or setting the values ​​of one or more displayed parameters and / or menu items of the software executed in respiratory ventilation device 110. In some embodiments, knob 313 can be rotated and / or pressed. For example, subject 180 can rotate knob 313 to adjust the pressure or humidity of the respiratory gas, etc. As another example, subject 180 can press knob 313 to confirm an adjusted (or set) parameter, select a menu item, exit a function interface, etc. As another example, subject 180 can long-press knob 313 (or short-press knob 313 twice) to enter a physician interface. The physician interface allows the physician to adjust and / or set one or more parameters related to respiratory ventilation device 110. Home button 314 is pressed to switch to the main interface of the software. In some embodiments, long-pressing home button 314 can mute the hardware and / or software of respiratory ventilation device 110. One or more of the switch key 311 , the display panel 312 , the knob 313 , and the home button 314 may be disposed on the front side, the back side, the top side, the left side, or the right side of the respiratory ventilation device 300 .

[0252] like Figure 3A As shown, the liquid chamber 320 may include a box 322 and a box cover 321. The liquid chamber 320 may be detachably connected to the main body 310 of the respiratory ventilation device 300 (see Figure 3D In some embodiments, liquid chamber 320 can be removably connected to body 310 of respiratory ventilation device 300. A user (e.g., subject 180) can remove liquid chamber 320 from respiratory ventilation device 300 to facilitate filling tank 322 with liquid, exchanging liquid in tank 322, cleaning tank 322, and / or sterilizing liquid chamber 320. Further description of liquid chamber 320 can be found elsewhere in this application (e.g., Figure 18A , 18B, 23A, 26B, 30A, 30B, 36A, and 36B and their descriptions). Figure 3A As shown, for illustrative purposes, the liquid chamber 320 is disposed on the right side of the body 310. It should be noted that in some embodiments, the liquid chamber 320 may be disposed on the left side of the body 310.

[0253] like Figure 3BAs shown, the respiratory ventilation device 300 may include a gas inlet 332 and a gas outlet 331. In some embodiments, the body 310 of the respiratory ventilation device 300 may include a shell. The shell may include a first side wall (e.g., located at the junction between the body 310 and the liquid chamber 320) and a second side wall (e.g., a rear side). The first side wall may be configured to discharge pressurized respiratory gas. The gas inlet 332 may be disposed on the body 310. In some embodiments, the gas inlet 332 may be disposed on the second side wall of the shell of the body 310 of the respiratory ventilation device 300. In some embodiments, the gas inlet 332 may be disposed on the front side, the rear side, or the top side of the respiratory ventilation device 300. In some embodiments, the gas inlet 332 may be disposed on a side of the respiratory ventilation device 300 opposite the liquid chamber 320. As Figure 3A and 3B As shown, since the liquid chamber 320 is disposed on the right side of the main body 310, the gas inlet 332 can be disposed on the left side of the respiratory ventilation device 300. Figure 3B As shown, a gas outlet 331 is provided on the main body 310. The gas outlet 331 can be provided on the same side of the respiratory ventilation device 300 as the gas inlet 332. In some embodiments, the gas outlet 331 and the gas inlet port 332 can be provided on different sides of the respiratory ventilation device 300. In some embodiments, the gas outlet 331 can be provided on the liquid chamber 320. In some embodiments, the respiratory ventilation device 300 can include or be equipped with one or more gas filter units (e.g., a coarse filter, a fine filter, etc.) inside the gas inlet 332 to filter the respiratory gas entering the gas inlet 332.

[0254] like Figure 3C As shown, the respiratory ventilation device 300 may include a gas filter component 340. The gas filter component 340 may be configured to filter the respiratory gas entering the respiratory ventilation device 300. The gas filter component 340 may be detachably connected to the gas inlet 332 of the respiratory ventilation device 300 (see Figure 3D ). The gas filter component 340 may include a coarse filter and / or a fine filter ( Figures 3A-3D It should be noted that the gas filter component 340 may be optional. In some embodiments, the respiratory ventilation device 300 may not include the gas filter component 340. Figure 1 The gas filter component 340 is shown. Figure 3D As shown, the liquid chamber 320 and / or the gas filter component 340 can be removably connected to the body 310 of the respiratory ventilation device 300. Further description of the gas filter component 340 can be found elsewhere in this application (e.g., Figures 6A-7B and its description).

[0255] like Figure 3CAs shown, respiratory ventilation device 300 may include a first interface 350, a second interface 360, and a third interface 370. First interface 350 may be configured to provide power to heating device 224 of respiratory ventilation device 300. Second interface 360 ​​may be configured as an interface for software upgrades and / or data reading (or transmission). Third interface 370 may be configured to provide power to respiratory ventilation device 300.

[0256] Figure 4 An exemplary process for delivering breathing gas according to some embodiments of the present application is shown. In some embodiments, Figure 4 One or more operations of the process 400 shown in FIG. 4 include: Figure 1 The system 100 shown implements a method for delivering breathing gas. Figure 4 For example, Figure 4 The illustrated process may be stored in the form of instructions in storage device 150 and called and / or executed by processing device 140. As another example, a portion of process 400 may be implemented on respiratory ventilation device 110. The illustrated process presented below is for illustrative purposes. In some embodiments, the process may be accomplished using one or more additional operations not described and / or without one or more operations discussed. In addition, Figure 4 The operations of the processes illustrated and the order in which they are described below are not intended to be limiting.

[0257] At 410, the respiratory ventilation device 110 (e.g., the control module 260) may activate one or more components of the respiratory ventilation device 110. In some embodiments, the respiratory ventilation device 110 may be activated upon a boot operation (e.g., a user pressing a power button on the respiratory ventilation device 110). In some embodiments, the control module 260 may load a boot program from a storage device (e.g., RAM, ROM, flash memory, solid-state digital (SD) memory card, etc.) of the respiratory ventilation device 110, load a user program from the storage device of the respiratory ventilation device 110, activate one or more peripheral devices of the control module 260 (e.g., a communication interface, a timer, an AD acquisition interface, an indicator light, a button, a knob, a power switch, etc.), activate one or more sensors, activate the gas pressurization unit 210, activate one or more configuration parameters, and / or activate one or more therapy parameters. In some embodiments, control module 260 may access a random access memory of respiratory ventilation device 110, read one or more parameters from a storage device (e.g., non-volatile memory, flash memory, SD card) on the main body of respiratory ventilation device 110 and / or network 120, and / or initiate detection module 250. In some embodiments, control module 260 may initiate a program that continuously reads information from detection module 250 and uses at least the information read from detection module 250 and one or more parameters to control the pressure of the pressurized respiratory gas. In some embodiments, the parameters read from a storage device (e.g., non-volatile memory, flash memory, SD card) on the main body of respiratory ventilation device 110 and / or network 120 may include one or more thresholds associated with an upper pressure limit, an upper air leak limit for the pressurized respiratory gas, a lower air leak limit for the pressurized respiratory gas, a lower limit for the pressurized respiratory gas, a lower respiratory rate limit, or a lower input voltage limit for the respiratory ventilation device 110.

[0258] At 420, respiratory ventilation device 110 may deliver breathing gas to a user (e.g., subject 180). In some embodiments, control module 260 may control or adjust the rotational speed of gas pressurizing unit 210 to pressurize the breathing gas, and the pressurized breathing gas may be distributed (or delivered) to subject 180 via one or more gas channels, breathing tube 160, and / or subject connection 170 of respiratory ventilation device 110. In some embodiments, control module 260 may adjust the rotational speed of gas pressurizing unit 210 to delay pressurizing the breathing gas after respiratory ventilation device 110 is activated. In some embodiments, the delay may be preset by the user.

[0259] At 430, respiratory ventilation device 110 may detect information related to the respiratory gas and / or subject 180. In some embodiments, control module 260 may cause detection module 250 (e.g., one or more sensors) to detect one or more parameters (e.g., pressure) of the pressurized respiratory gas. The detected information may include parameters related to the respiratory gas, exhaled gas from subject 180, and / or the operating state of respiratory ventilation device 110. Further description of the parameters may be found elsewhere in this application (e.g., Figure 2 and its description). In some embodiments, control module 260 may determine one or more parameters based on the operating conditions of one or more components of respiratory ventilation device 110. For example, control module 260 may determine the pressure of the respiratory gas based on the rotation speed, input voltage, and / or real-time power of gas pressurizing unit 210. In some embodiments, control module 260 may adjust the rotation speed of gas pressurizing unit 210 to maintain the detected pressure of the pressurized breath within a certain range.

[0260] At 440, respiratory ventilation device 110 may determine whether an abnormal condition has been identified. In some embodiments, control module 260 may identify the abnormal condition based on a comparison between the current state of respiratory ventilation device 110 and a plurality of parameters read from a storage device of the main body of respiratory ventilation device 110 and / or network 120. In some embodiments, the current state of respiratory ventilation device 110 may include, for example, the pressure of the respiratory gas, the amount of air leakage of the pressurized respiratory gas, the respiratory rate, the input voltage of gas pressurization unit 210, etc. In response to determining that an abnormal condition has been identified, process 400 may proceed to 450. In response to determining that no abnormal condition has been identified, process 400 may return to 420, i.e., respiratory ventilation device 110 may continue to deliver respiratory gas.

[0261] At 450, respiratory ventilation device 110 may provide an alarm or reminder to the user (e.g., subject 180). The alarm or reminder may include voice, text, etc. For example, in response to an abnormal situation, respiratory ventilation device 110 may sound an alarm, respiratory ventilation device 110 may display a notification on a display, and / or control module 260 may send a command to terminal 130 to display a notification or sound an alarm, etc. In some embodiments, after respiratory ventilation device 110 provides the alarm or reminder to the user, the process may return to 420, i.e., respiratory ventilation device 110 may continue to deliver breathing gas.

[0262] Figures 5A-5E FIG. 2 shows an exemplary gas channel of a respiratory ventilation device according to some embodiments of the present application. Figure 5AAs shown in FIG, a flow of respiratory gas (e.g., ambient gas) can flow into the respiratory ventilation device 300 from a gas inlet 332 and out of the respiratory ventilation device 300 from a gas outlet 331. In some embodiments, the respiratory gas pressure therapy device 300 can further include a gas filter component 340 mounted on the outside of the gas inlet 332. The respiratory gas can be filtered by the gas filter component 340 before entering the respiratory ventilation device 300 through the gas inlet 332. Figure 5B As shown, one side of the body 310 connected to the liquid chamber 320 may include an outlet port 501 and an inlet port 502. The respiratory gas filtered by the gas filter device 340 may be pressurized by the gas pressurizing unit 210 and then pass through the outlet port 501 of the body 310. Figure 5C As shown, the liquid chamber 320 may include a tank 322 and a tank cover 321, and the side of the tank cover 321 attached to the main body 310 may include an outlet port 503 and an inlet port 504. The filtered and pressurized respiratory gas passing through the outlet port 501 of the main body 310 can enter the liquid chamber 320 from the inlet port 504 of the tank cover 321 and be humidified in the tank 322. The outlet port 503 of the tank cover 321 can output the pressurized and humidified respiratory gas. Figure 5D and 5E As shown, the pressurized and humidified respiratory gas output by the outlet port 503 of the tank cover 321 can return to the main body 310 from the inlet port 502 of the main body 310 and flow out of the respiratory pressure therapy device 300 from the gas outlet 331 of the respiratory ventilation device 300.

[0263] It should be noted that the above description of the respiratory ventilation device 300 is provided for illustrative purposes only and is not intended to limit the scope of the present application. For those skilled in the art, various changes and modifications can be made under the teachings of the present application. However, those changes and modifications do not depart from the scope of the present application. In some embodiments, the respiratory ventilation device 300 may not include the humidification component 220 (i.e., the liquid chamber 320 can be omitted). In some embodiments, the gas outlet 331 of the respiratory ventilation device 300 may be provided on the liquid chamber 320, and therefore, the inlet port 502 of the respiratory ventilation device 300 and the outlet port 503 of the liquid chamber 320 can be omitted. That is, the pressurized respiratory gas can be introduced into the liquid chamber 320 via the outlet 501 of the main body 310 and the inlet 504 of the liquid chamber 320, and then discharged to the breathing tube via the gas outlet on the liquid chamber 320. Accordingly, the humidified respiratory gas may not flow back to the main body 310.

[0264] Figures 6A-6E An exemplary gas filtering component according to some embodiments of the present application is shown. Figure 6A FIG. 6 is a first isometric view of the gas filter component 600 , showing the front, left side, and top side of the gas filter component 600 . Figure 6B A first exploded view of the gas filtering component 600 is shown. Figure 6C The internal structure of the housing of the gas filtering component 600 is shown. Figure 6D A second exploded view of the gas filtering component 600 is shown. Figure 6E FIG. 6 is a second isometric view of the air filter component 600 , showing the back, left, and top sides of the air filter component 600 . In some embodiments, the air filter component 600 can be removably coupled to the air inlet 112 of the respiratory ventilation device 110 .

[0265] The gas filter component 600 may include a housing 601 and one or more gas filter units (eg, a first gas filter unit 605, a second gas filter unit 606, etc.). In some embodiments, the respiratory gas (eg, ambient gas) may be passed through the Figure 6A The direction indicated by the arrow in the middle portion of the figure is through the air filter component 600 into the respiratory ventilation device 300 (e.g., when the air boosting unit 210 is in operation). The air filter component 600 (e.g., the first air filter unit 605, the second air filter unit 606, etc.) can filter the respiratory gas entering the respiratory ventilation device 300. In some embodiments, one or more air filter units can filter the respiratory gas at different levels.

[0266] The housing 601 may include a gas inlet port 602 and a gas outlet port 609. The gas inlet port 602 may include a first cover 604. The gas outlet port 609 may include a second cover 607. In some embodiments, the first cover 604 may have the same dimensions as the gas inlet port 602. In some embodiments, the first cover 604 may include at least one aperture to allow respiratory gas to enter the gas filter component 600. In some embodiments, the second cover 607 may have smaller dimensions than the gas outlet port 609. In some embodiments, the second cover 607 may include at least one aperture to allow respiratory gas to exit the gas filter component 600 and enter the respiratory ventilation device 300. In some embodiments, the first cover 604 may be removably connected to the housing 601. In some embodiments, the first cover 604 may include a frame. In some embodiments, the frame of the first cover 604 may include one or more apertures or recesses, and the housing 601 may include one or more corresponding protrusions (or vice versa) to allow the first cover 604 to be connected to the housing 601. In some embodiments, the second cover plate 607 can be fixed to the gas outlet end 609 of the housing 601 by a sealing connection. In some embodiments, the second cover plate 607 and the housing 601 can be configured as a single piece. In some embodiments, the first cover plate 604 and / or the second cover plate 607 can be configured to prevent deformation of one or more gas filter units (e.g., the first gas filter unit 605 and / or the second gas filter unit 606) of the gas filter component 600. In some embodiments, the housing 601 of the gas filter component 600 can be configured to facilitate disassembly of the gas filter component 600 and / or facilitate replacement of the gas filter units (e.g., the first gas filter unit 605 and / or the second gas filter unit 606) of the gas filter component 600.

[0267] In some embodiments, the gas filter component 600 may have a stepped or conical three-dimensional structure. In some embodiments, the gas filter component 600 may have a rectangular parallelepiped shape. In some embodiments, the gas filter component 600 may have a funnel shape. In some embodiments, the gas outlet port 609 of the housing 601 may have a funnel shape. In some embodiments, the gas inlet port 602 may have the same size as the gas outlet port 609. In some embodiments, the gas inlet port 602 may have a larger size than the gas outlet port 609, thereby increasing the intake amount of respiratory gas flowing into the gas filter component 600. In some embodiments, the gas outlet port 609 may have a funnel shape so that the gas outlet port 609 can be connected to the gas inlet 112 of the respiratory ventilation device 110. In some embodiments, the cross-section (perpendicular to the inflow direction of the respiratory gas) of the air inlet end 602 (or the first cover plate 604) of the gas filtering component 600 can be larger than the cross-section of the gas outlet end 609 (or the second cover plate 607), which means that the air inlet area of ​​the air inlet end 602 (or the first cover plate 604) is larger than the air inlet area of ​​the air outlet end 609 (or the second cover plate 607).

[0268] In some embodiments, the first cover plate 604 (or the gas inlet end 602) and the second cover plate 607 (or the gas outlet end 609) may have the same shape. In some embodiments, the first cover plate 604 (or the gas inlet end 602) and the second cover plate 607 (or the gas outlet end 609) may have different shapes. For example, the first cover plate 604 and the second cover plate 607 may have the shape of a rounded rectangle. As another example, the first cover plate 604 and the second cover plate 607 may have a circular shape. As yet another example, the first cover plate 604 may have the shape of a rounded rectangle, while the second cover plate 607 may have a circular shape. As yet another example, the first cover plate 604 may have a circular shape, while the second cover plate 607 may have the shape of a rounded rectangle.

[0269] The first cover plate 604 may include a plurality of holes. The holes of the first cover plate 604 may be configured to facilitate the breathing gas to flow through the first cover plate 604 and reach the gas filtration unit to be filtered. After flowing through the plurality of holes of the first cover plate 604, the breathing gas may be filtered by the gas filtration unit. The filtered breathing gas may then flow through the second cover plate 607 and enter the gas inlet 112 of the respiratory ventilation device 110. The second cover plate 607 may include one or more holes. The holes of the second cover plate 607 may be configured to facilitate the filtered breathing gas to flow through the second cover plate 607 and reach the gas inlet 112. In some embodiments, the number of holes provided on the first cover plate 604 may be greater than the number of holes provided on the second cover plate 607.

[0270] In some embodiments, the holes of the first cover plate 604 and / or the second cover plate 607 may have a strip, circle, rectangle, triangle, diamond, hexagon, star, or similar shape, or any combination thereof. The holes may have a relatively small size so that the user's fingers cannot be inserted. In some embodiments, the holes of the first cover plate 604 and / or the second cover plate 607 may be evenly distributed. Figure 6A As shown in FIG, 198 circular holes are evenly distributed on the first cover plate 604, forming an array of 11 rows and 18 columns. Figure 6E As shown in FIG, 16 circular holes are evenly distributed on the second cover plate 607, forming an array of 4 rows and 4 columns. It should be noted that in some embodiments, the holes of the first cover plate 604 and / or the second cover plate 607 may be unevenly distributed. In some embodiments, the holes of the first cover plate 604 and / or the second cover plate 607 may help regulate the flow of respiratory gas entering the gas inlet 112 of the respiratory ventilation device 110, thereby reducing the noise generated by the flow.

[0271] In some embodiments, the first air filter unit 605 may be a coarse filter. In some embodiments, the coarse filter may be positioned adjacent to the first cover plate 604. The coarse filter may include a coarse filter sponge (also known as a coarse filter foam). In some embodiments, the first air filter unit 605 may include one or more layers of coarse filter sponge (or multiple layers of filter membrane). The coarse filter sponge may be configured to filter or adsorb solid particles (e.g., dust, resin, pollen, etc.) from respiratory gas entering the air filter component 600. In some embodiments, the size of particles filtered by the coarse filter sponge may be greater than 5 microns. In some embodiments, the coarse filter may further include a fixing portion configured to secure the coarse filter sponge within the housing 601.

[0272] In some embodiments, the second air filter unit 606 may be a fine filter. The fine filter may include a fine filter sponge (also referred to as a fine filter foam). In some embodiments, the second air filter unit 606 may include one or more layers of fine filter sponge (or multiple layers of ultrafiltration membrane). The fine filter sponge may be configured to filter or adsorb solid particles larger than 1 micron, such as PM2.5 particles. Exemplary components of the coarse filter sponge and / or fine filter sponge may include synthetic fibers, polyester fibers, glass fibers, or any combination thereof. In some embodiments, the fine filter may further include a securing portion configured to secure the fine filter sponge within the housing 601. In some embodiments, the housing 601 may include one or more frames configured to secure the first air filter unit 605 and / or the second air filter unit 606. In some embodiments, the first air filter unit 605 may be positioned closer to the first cover plate 604 than the second air filter unit 606 (i.e., the distance between the first air filter unit 605 and the first cover plate 604 may be smaller than the distance between the second air filter unit 606 and the first cover plate 604).

[0273] In some embodiments, the second air filter unit 606 can be installed behind the first air filter unit 605 along the air flow direction. In some embodiments, respiratory gas may first flow through the first air filter unit 605 and then through the second air filter unit 606. In some embodiments, one or more grilles can be provided between the first air filter unit 605 and the second air filter unit 606, creating a certain distance between the first and second air filter units 605, 606. This facilitates the flow of respiratory gas through the first and second air filter units 605, 606 and enhances the filtering effect of the first and second air filter units 605, 606. In some embodiments, the first and second air filter units 605, 606 can be independently installed in the housing 601. In some embodiments, the replacement cycle of the first air filter unit 605 can be shorter than that of the second air filter unit 606. In some embodiments, the first and second air filter units 605, 606 can be detachably connected to the housing 601. The detachable connection can include a snap-fit ​​connection, a threaded connection, a hinge connection, or any combination thereof.

[0274] In some embodiments, the housing 601 of the gas filter component 600 may further include a connecting component configured to connect the gas filter component 600 to the gas inlet 112 of the respiratory ventilation device 110. Figure 6EAs shown, the connection portion may include a positioning claw 608 located on the rear side of the housing 601 and a snap claw 603 located on the left (or right) side of the housing 601. By pressing and / or holding the snap claw 603, the user (e.g., subject 180) can easily connect (or disconnect) the gas filter component 600 to (or from) the respiratory ventilation device 110. Therefore, a pair of limiting holes MZ0204 (see FIG. MZ02B ) can be provided on both sides of the gas inlet 112, respectively engaging with the snap claws 603 on both sides, so that the gas filter component 600 can be fixed to the respiratory ventilation device 110.

[0275] To ensure a sealed connection between the gas filter component 6 and the respiratory ventilation device 110, a sealing element (e.g., a silicone gasket) may be provided between the gas outlet end 609 and the gas inlet 112 of the respiratory ventilation device 110. For example, the sealing element may be provided at the gas outlet end 609. As another example, the sealing element may be provided at the gas inlet 112 of the respiratory ventilation device 110 (see MZ0206 in FIG. MZ02B ).

[0276] In some embodiments, the gas filter component 600 may further include a first baffle (not shown). In some embodiments, the area of ​​the first baffle may be smaller than the gas inlet end 602 of the housing 601. In some embodiments, the first baffle may be installed in the housing 601 closer to the gas inlet end 602 than the gas filter unit. In some embodiments, the coarse filter may be positioned closer to the gas inlet end 602 of the housing 601 than the fine filter. For example, the first baffle may be installed between the first cover plate 604 and the first gas filter unit 605. In some embodiments, the first baffle may allow respiratory gas to flow into the gas filter component 600 from one or more sides (e.g., four sides) of the first baffle, thereby reducing noise generated by the gas flow.

[0277] In some embodiments, the gas filtering component 600 can be disposed between the gas outlet of the respiratory ventilation device 300 and the breathing tube 160. In some embodiments, the gas outlet end 609 can have a funnel shape so that the gas outlet end 609 can be connected to the breathing tube 160.

[0278] It should be noted that in some embodiments, the air filter component 600 can be configured to protrude from the housing of the respiratory ventilation device 110. In some embodiments, a certain distance can exist between the first air filter unit 605 and the second air filter unit 606. In some embodiments, the air filter component 600 can be equipped with one or more grilles between the first air filter unit 605 and the second air filter unit 606. In some embodiments, the first air filter unit 605 can be disposed on the first cover plate 604. In some embodiments, the second air filter unit 606 can be disposed on the second cover plate 607. In some embodiments, both the first air filter unit 605 and the second air filter unit 606 can be disposed on the first cover plate 604. In some embodiments, both the first air filter unit 605 and the second air filter unit 606 can be disposed on the second cover plate 607. In some embodiments, the number of holes disposed on the first cover plate 604 can be greater than the number of holes disposed on the second cover plate 607.

[0279] Figure 7A and 7B An exemplary gas filtration unit according to some embodiments of the present application is shown. Figure 7A FIG. 2 is an isometric view of respiratory ventilation device 300 (without humidification assembly 220 ), showing the back side of respiratory ventilation device 300 . Figure 7B An exploded view of respiratory ventilation apparatus 300 is shown.

[0280] The respiratory ventilation device 300 may include a third gas filter unit 702. In some embodiments, the third gas filter unit 702 may be disposed at the gas inlet 701 of the respiratory ventilation device 300. In some embodiments, the third gas filter unit 702 may be configured to filter the respiratory gas (e.g., ambient gas) entering the gas inlet 701. The third gas filter unit 702 may include a coarse filter and / or a fine filter. Further description of the coarse filter and / or the fine filter may be found elsewhere in this application (e.g., Figures 6A-6E In some embodiments, third air filter unit 702 may be installed within the air inlet of respiratory ventilation device 300, between the air inlet of respiratory ventilation device 300 and the air inlet of the gas pressurizing unit, at the air inlet of the gas pressurizing unit, at the air outlet of the gas pressurizing unit, between the air outlet of the gas pressurizing unit and the air outlet of respiratory ventilation device 300, at the air outlet of respiratory ventilation device 300, at breathing tube 160, and / or subject connection device 170. For example, third air filter unit 702 may be positioned between the air outlet of respiratory ventilation device 300 and between breathing tube 160.

[0281] In some embodiments, the gas inlet 701 may include or be equipped with a second baffle 705 and / or a third baffle 703. In some embodiments, one or more restriction holes 704 may be provided on one or more sides of the gas inlet 701. The restriction holes 704 may be configured to facilitate the fixing of additional gas filtering components (e.g., Figures 6A-6E The gas filter component 600 shown in FIG. 7 is shown in FIG. 7 . The second baffle 705 and the third baffle 703 can be configured to secure the third gas filter unit 702 at the gas inlet 701. In some embodiments, the third gas filter unit 702 can be secured between the second baffle 705 and the third baffle 703. The second baffle 705 can include a plurality of holes so that the respiratory gas can flow through the second baffle 705. The holes can have various shapes. For example, Figure 7B As shown, the holes may have a strip shape. It should be noted that in some embodiments, if additional gas filtering components (e.g., Figures 6A-6E ), the second baffle 705 can be removed from the gas inlet 701. If the additional gas filter component is not used, the second baffle 705 can be installed at the gas inlet 701, and the second baffle 705 can cover the restriction hole 704. In some embodiments, the third baffle 703 can be a transverse baffle. The third baffle 703 can include a plurality of protrusions configured to support the third gas filter unit 702. In some embodiments, the edge 706 of the gas inlet 701 can include or be equipped with a sealing element to form a sealed connection between the additional gas filter component and the gas inlet 701.

[0282] In some embodiments, the respiratory ventilation device 300 may include a fourth gas filtration unit. The fourth gas filtration unit may be configured to filter pungent odors and / or one or more harmful gases (e.g., formaldehyde) from one or more gas channels of the respiratory ventilation device 300. In some embodiments, the fourth gas filtration unit may include a membrane made of one or more nanomaterials having adsorption capacity. The one or more nanomaterials may include activated carbon, graphene, graphene oxide, carbon nanotubes, etc., or any combination thereof. The one or more nanomaterials may have a large specific surface area. A large specific surface area may indicate a large number of surface atoms. Surface atoms may be more reactive than inner-layer atoms and may be more likely to adsorb gas molecules. Therefore, a larger specific surface area of ​​a nanomaterial may indicate a stronger adsorption capacity.

[0283] If the respiratory ventilation device 300 is used by a patient in a hospital, the pungent odor may be the smell of hospital disinfectant. If the respiratory ventilation device 300 is used by a user at home, the pungent odor may be the smell of smoking and / or cooking smoke. In some embodiments, the fourth gas filter unit may be installed outside the gas inlet of the respiratory ventilation device 300, at the gas inlet of the respiratory ventilation device 300, inside the gas inlet of the respiratory ventilation device 300, between the gas inlet of the respiratory ventilation device 300 and the gas inlet of the gas pressurizing unit, inside the gas inlet of the gas pressurizing unit, at the gas outlet of the gas pressurizing unit, between the gas outlet of the gas pressurizing unit and the gas outlet of the respiratory ventilation device 300, at the gas outlet of the respiratory ventilation device 300, inside the breathing tube 160, and / or inside the subject connection device 170. For example, the fourth gas filter unit may be located between the gas outlet of the respiratory ventilation device 300 and the breathing tube 160.

[0284] In some embodiments, the respiratory ventilation device 300 may include a fifth gas filtration unit. The fifth gas filtration unit can be configured to filter bacteria from one or more gases in one or more gas channels of the respiratory ventilation device 300. In some embodiments, after long-term use, a large number of bacteria can spread in the respiratory ventilation device 300. The fifth gas filtration unit may include a membrane for filtering bacteria. The membrane can use one or more physical or chemical techniques to achieve bacterial filtration. The physical or chemical techniques may include a high-efficiency particulate air filter (HEPA) of H13 grade or above, plasma sterilization technology, photocatalyst sterilization technology (e.g., a catalyst with titanium dioxide as a base material, CH-CUT technology with CH-CUT nanomaterials as a core, etc.), semiconductor catalytic sterilization technology, etc., or any combination thereof. In some embodiments, the fifth air filter unit can be installed outside the air inlet of the respiratory ventilation device 300, at the air inlet of the respiratory ventilation device 300, inside the air inlet of the respiratory ventilation device 300, between the air inlet of the respiratory ventilation device 300 and the air inlet of the gas pressurizing unit, at the air inlet of the gas pressurizing unit, at the air outlet of the gas pressurizing unit, between the air outlet of the gas pressurizing unit and the air outlet of the respiratory ventilation device 300, at the air outlet of the respiratory ventilation device 300, within the breathing tube 160, and / or within the subject connection device 170. For example, the fifth air filter unit can be located between the air outlet of the respiratory ventilation device 300 and the breathing tube 160. In some embodiments, considering that moisture may be more suitable for bacterial growth, the fifth air filter unit can be installed in the air passage between the liquid chamber 222 and the air outlet of the respiratory ventilation device 300. In some embodiments, the respiratory ventilation device 300 can include one or more air filter units (e.g., a third air filter unit, a fourth air filter unit, a fifth air filter unit, etc.) installed in the breathing tube 160 and / or the subject interface 170.

[0285] It should be noted that in some embodiments, the filter sponges of one or more of the first, second, third, fourth, and fifth air filter units can be made of different materials, have different shapes, and / or different colors. In some embodiments, to facilitate replacement of the filter units, the first, second, third, fourth, and / or fifth air filter units can be mounted at a connection between two components of the respiratory ventilation device 300 (e.g., a connection between the main body of the respiratory ventilation device 300 and the liquid chamber, a connection between the gas outlet of the respiratory ventilation device 300 and the breathing tube 160, a connection between the breathing tube 160 and the subject connection device 170, etc.). In some embodiments, the filter units can be removed from the respiratory ventilation device 300 and stored under appropriate conditions (e.g., a drying room, sterilizer, storage box, dustproof box, etc.).

[0286] In some embodiments, an ultrasonic nebulizer can be used in humidification assembly 220 to generate droplets of one or more therapeutic drugs and / or one or more liquids and introduce them into the respiratory gas. In some embodiments, one or more filter units described above can be used to filter harmful particles from the droplets of therapeutic drugs and / or liquids and / or respiratory gas. In some embodiments, the filter sponge of the filter unit can include a hydrophobic surface.

[0287] Figures 8A-8D Different views of an exemplary noise reduction assembly are shown according to some embodiments of the present application. Figure 8A An axonometric view of the noise reduction assembly 8 is shown. Figure 8B The bottom surface of the noise reduction assembly 8 is shown. Figure 8C The internal structure of the noise reduction assembly 8 with sound absorbing material is shown. Figure 8D The internal structure of the noise reduction assembly 8 is shown without the sound absorbing material. The noise reduction assembly 8 can be configured to reduce the noise generated by the gas pressurization unit 808 and / or the noise generated by the (pressurized) breathing gas flowing in the gas passage of the respiratory ventilation device 110. The noise reduction assembly 8 can include a noise reduction box 801, one or more sound absorbing materials, and / or one or more frames.

[0288] In some embodiments, the noise reduction box 801 can be a sealed box having an air inlet 809 (e.g., an air inlet for introducing respiratory gas into the noise reduction box 801) and an air outlet 810 (e.g., a gas outlet for outputting (pressurized) respiratory gas). In some embodiments, the air inlet 809 of the noise reduction box 801 can be sealedly connected to the inside of the gas inlet 112 of the respiratory ventilation device 110, so that the respiratory gas entering the gas inlet 112 of the respiratory ventilation device 110 can flow directly into the noise reduction box 801. In some embodiments, the air inlet 809 of the noise reduction box 801 can be configured as the gas inlet 112 of the respiratory ventilation device 110.

[0289] Noise reduction box 801 can house a gas pressurizing unit 808. Gas pressurizing unit 808 can include a blower configured to generate a pressurized flow of breathing gas based on the gas introduced into respiratory ventilation device 110. In some embodiments, after being filtered by one or more gas filtration units mounted within the gas inlet, the breathing gas can enter gas pressurizing unit 808 and be pressurized by the blower, thereby generating pressurized breathing gas. The pressurized breathing gas can be discharged from noise reduction box 801 via gas outlet 810 to the internal gas passageway of respiratory ventilation device 110.

[0290] In some embodiments, the noise reduction box 801 may include one or more sound absorbing materials (e.g., L-shaped sound absorbing material 804, dotted-line sound absorbing material 802, rectangular sound absorbing material 803). The sound absorbing material may be disposed on the inner wall of the noise reduction box 801. Figure 8C As shown, the L-shaped sound absorbing material 804 and the dotted-line sound absorbing material 802 can be disposed near the air inlet 809 , and the rectangular sound absorbing material 803 can be disposed near the gas pressurizing unit 808 .

[0291] In some embodiments, the one or more sound-absorbing materials may include porous materials, panel materials, resonant materials, or any combination thereof. Exemplary porous materials include carpet, draperies, spray cellulose, aerated plaster, fibrous mineral wool and fiberglass, open-cell foam, felt or cast porous ceiling tiles, or any combination thereof. In some embodiments, porous materials may be the most commonly used sound-absorbing materials. In some embodiments, the thickness of the porous material may be important in sound absorption. The sound-absorbing effect of porous materials may stem from the fact that sound can penetrate the porous material upon impacting its surface. In some embodiments, sound energy can be converted into heat, resulting in only a relatively small portion being reflected as sound energy. In other words, the porous material can absorb a portion of the sound. In some embodiments, the panel material may be a non-rigid, non-porous material. The panel material can be placed over a space that vibrates in a bending mode in response to the sound pressure exerted by adjacent gas molecules. Exemplary panel (or membrane) materials may include thin wood. In some embodiments, the panel material may be configured to absorb low-frequency noise. Resonant materials may be configured to absorb sound within a relatively narrow frequency range. Resonant materials may include some perforated materials and materials with openings (holes and slots). An exemplary resonant material may include a Helmholtz resonant material, which may have the shape of a bottle. The resonant frequency may be controlled by the size of the opening, the length of the neck, and the volume of gas trapped in the bottle-shaped chamber.

[0292] In some embodiments, the noise reduction box 801 may further include one or more frames configured to hold one or more sound absorbing materials. In some embodiments, the size and / or shape of the frames and the size and / or shape of the corresponding sound absorbing materials may match. Figure 8D As shown, frame 805 and frame 806 can be configured to fix L-shaped sound absorbing material 804 and dotted line sound absorbing material 802 on the inner wall of noise reduction box 801 respectively. Frame 807 can be configured to fix rectangular sound absorbing material 803. It should be noted that not all sound absorbing materials and frames are in Figure 8C and Figure 8D For the purpose of illustration, only three sound absorbing materials and their corresponding frames are described in the preset disclosure, but the subject matter is not intended to limit the scope of the present application.

[0293] like Figure 8C and Figure 8DAs shown, one or more sound-absorbing materials and / or one or more frames can form a gas channel with one or more twists and / or one or more loops in the noise reduction box 801. The gas channel in the noise reduction box 801 can be divided into a plurality of sub-gas channels with different cross-sections. The noise generated by the blower may continuously collide with the sound-absorbing material, resulting in that the vibration energy can be continuously absorbed and the noise can be effectively reduced in decibels. In some embodiments, the sub-gas channel can form at least two damping spaces, including a first damping space near the gas inlet 809 and a second damping space surrounding the gas booster unit 808. The first damping space and the second damping space can be connected by the sub-gas channel therebetween. In some embodiments, at least two damping spaces can provide a larger cone than the respiratory gas for the sub-gas channel connecting them, and then a relatively low respiratory gas resistance can be achieved at a relatively high speed. Therefore, the noise generated by the flow of respiratory gas (especially the high-frequency component of the noise) can be effectively reduced.

[0294] Figures 9A-9E 1 shows an exemplary connection between a noise reduction assembly and a main body of a respiratory ventilation device according to some embodiments of the present application. In some embodiments, a noise reduction box 801 can be secured between a housing cover 901 of the respiratory ventilation device 110 and a bottom plate 902 of the respiratory ventilation device 110. In some embodiments, the noise reduction box 801 can include one or more protrusions and / or one or more grooves. In some embodiments, the housing cover 901 and / or the bottom plate 902 can include one or more corresponding grooves and / or one or more corresponding protrusions configured to cooperate with the protrusions and / or grooves so that the noise reduction box 801 can be secured between the housing cover 901 and the bottom plate 902.

[0295] Figures 10A-10C 1 shows an exemplary exploded view of a noise reduction assembly according to some embodiments of the present application. The noise reduction box 801 may include a box cover 1001, a box body MZ1003 and a filling component 1002. The noise reduction box 801 may accommodate a gas booster unit 808. In some embodiments, the filling component 1002 may be arranged around the gas booster unit 808. The filling component 1002 may include a plurality of sound absorbing materials, which are configured to reduce the noise generated in the noise reduction box 801. The gas booster unit 808 may include a gas inlet ( Figures 10A-10C 801) and a gas outlet 1004. The gas inlet of the gas pressurizing unit 808 can be configured to introduce the breathing gas from the noise reduction box 801 into the gas pressurizing unit 808. The gas outlet 1004 can be configured to discharge the pressurized breathing gas from the gas pressurizing unit 808 to the gas passageway of the main body of the respiratory ventilation device 110.

[0296] Figures 11A-11EFIG1 shows an exemplary connection between a gas pressurizing unit and a noise reduction box according to some embodiments of the present application. In some embodiments, the noise reduction box 801 may further include one or more supports (e.g., three supports) 1102 configured to support the gas pressurizing unit 808 in the interior space of the box body 1003 of the noise reduction box 801 (see FIG1 ). Figure 11E and 11F In some embodiments, the housing 1003 of the noise reduction box 801 may include one or more corresponding limiting holes 1104 configured to limit the position of the support members 1102. In some embodiments, each of the support members 1102 may include a supporting portion and a buffering portion. The supporting portion of each support member 1102 may be made of a hard material to secure the gas booster unit 808 in the noise reduction box 801. The buffering portion of each support member 1102 may be made of a flexible material (e.g., silicone) to dampen vibrations of the gas booster unit 808 to reduce noise.

[0297] In some embodiments, the gas pressurizing unit 808 may include a gas inlet 1103 configured to introduce respiratory gas from the noise reduction box 801 into the gas pressurizing unit 808. In some embodiments, the gas pressurizing unit 808 may include a connector 1101 configured to secure the gas pressurizing unit to the interior space of the noise reduction box 801. In some embodiments, the housing 1003 of the noise reduction box 801 may include a limiting groove 1105. The connector 1101 may be secured in the limiting groove 1105 so that the gas pressurizing unit 808 may be secured in the interior space of the noise reduction box 801 (see FIG. 1 ). Figure 11E and 11F )). In some embodiments, the connector 1101 can damp vibrations of the gas booster unit 808 in one or more directions. Further description of the connector 1101 can be found elsewhere in this application (e.g., Figure 13A and 13B and their descriptions).

[0298] Figures 12A-12C An exemplary gas pressurizing unit according to some embodiments of the present disclosure is shown. Figure 12A As shown, the gas pressurization unit 808 may include a connector 1101 and one or more supports 1102. The connector 1101 may be configured to secure the gas pressurization unit 808 to the interior space of the main body of the respiratory ventilation device 110. In some embodiments, the connector 1101 may be configured to suppress vibration of the gas pressurization unit 808 in one or more directions and / or prevent vibration transmission of the gas pressurization unit 808 (e.g., to the noise reduction box 801). Vibration of the gas pressurization unit 808 may be generated during transportation, operation, etc. In some embodiments, the connector 1101 may be detachably connected to the gas outlet 1004 of the gas pressurization unit 808.

[0299] Figure 12B 1 shows a side cross-sectional view of a connector 1101 according to some embodiments of the present disclosure connected to a blower. In some embodiments, the gas outlet 1004 of the gas pressurizing unit 808 can be connected to the connector 1101 by one or more threads. In some embodiments, the gas outlet 1004 of the gas pressurizing unit 808 can be connected to the connector 1101 by one or more protrusions and one or more corresponding grooves. In some embodiments, the inner surface of the gas outlet 1004 can be connected to the outer surface of the connector 1101. In some embodiments, as Figure 12B As shown, the inner surface of the connector 1101 can be connected to the outer surface of the gas outlet 1004. Figure 12C As shown, two annular grooves located in the inner surface of the connector 1101 can be connected to two annular protrusions located on the outer surface of the gas outlet 1004 of the gas pressurizing unit 808. In some embodiments, the connector 1101 can be made of a flexible material with elasticity (e.g., silicone), or the connector 1101 can include a flexible material with elasticity (e.g., silicone). In some embodiments, the gas outlet 1004 of the gas pressurizing unit 808 can be directly inserted into the connector 1101, or the gas outlet 1004 of the gas pressurizing unit 808 can be rotated relative to the gas pressurizing unit 808 so that the gas outlet 1004 can be connected to the connector 1101.

[0300] Figure 13A and 13B Exemplary connectors according to some embodiments of the present disclosure are shown. Figure 13A An axonometric view of connector 1101 is shown. Figure 13B A side cross-sectional view of the connector 1101 is shown. Figure 13A and 13B As shown, the connector 1101 may include a connecting portion 1301 and a fixing portion 1302. The connecting portion 1301 and the fixing portion 1302 may be made of the same or different materials. In some embodiments, the connecting portion 1301 may be configured to mate with the gas outlet 1004 (see FIG. Figure 12B ) connection and / or forming a sealed connection between connector 1101 and gas pressurizing unit 808. 1101 and gas pressurizing unit 808. In some embodiments, to prevent the gas outlet 1004 of gas pressurizing unit 808 from separating from connector 1301, connector 1301 can be made of one or more flexible materials (e.g., silicone) so that connector 1101 can withstand or dampen vibrations of gas pressurizing unit 808 caused by rough operation of respiratory ventilation device 110.

[0301] In some embodiments, fixing portion 1302 can be configured to fix connector 1101 to the interior space of the body of respiratory ventilation device 110 and / or to form a tight connection between connector 1101 and the body of respiratory ventilation device 110. In some embodiments, fixing portion 1302 can be configured to fix connector 1101 to a noise reduction box (e.g., Figure 8B The noise reduction box 801 shown in FIG) and / or a fastener is formed between the connecting member 1101 and the noise reduction box. Figure 11B As shown, the noise reduction box 801 may include one or more limiting grooves 1105 (e.g., fixing grooves) connected to the fixing portion 1302 of the connector 1101. In some embodiments, the gas pressurizing unit 808 can be fixed in a fixed position within the noise reduction box 801 by fixing two opposite sides of the fixing portion 1302 into the fixing grooves.

[0302] In some embodiments, the fixing portion 1302 can be made of one or more hard materials, such as Teflon, which is a thermoplastic polymer with relatively high strength and / or toughness. Figure 13A As shown, the fixing portion 1302 may have a sheet-like structure. In some embodiments, the fixing portion 1302 may include a hole configured to allow (pressurized) breathing gas to pass through. In some embodiments, the connecting portion 1301 may have a tubular structure. The tubular structure may include a first end 1303 and a second end 1304. In some embodiments, the first end 1303 of the connecting portion 1301 may be fixed to the fixing portion 1302. In some embodiments, the second end 1304 of the connecting portion 1301 may be connected to the outlet port of the gas pressurizing unit 808. The connecting portion 1301 may allow (pressurized) breathing gas to pass through the tubular structure to the hole in the fixing portion 1302. In some embodiments, the (pressurized) breathing gas may be discharged from the gas pressurizing unit 808 and flow continuously through the gas outlet 1004, the connecting portion 1301, the hole in the fixing portion 1302, the gas outlet 810 of the decompression tank 801, and enter the internal gas channel of the respiratory ventilation device 110.

[0303] In some embodiments, the connecting portion 1301 may include one or more annular structures. The one or more annular structures may be connected end to end. In some embodiments, a specific distance may be provided between each two adjacent annular structures in the one or more annular structures. In some embodiments, each of the one or more annular structures may include an outer annular structure and an inner annular structure. The outer annular structure may be connected to the fixing portion 1302. The inner annular structure may be connected to the noise reduction box, fix the implementation connector 1101 to the noise reduction box, and / or form a fastened connection between the connector 1101 and the noise reduction box.

[0304] In some embodiments, as Figure 13B As shown, the connecting portion 1301 and the fixing portion 1302 can be configured as an integral part. In some embodiments, the second end 1304 of the connecting portion 1301 can have an annular double-layer structure, which includes an inner layer 1305 and an outer layer 1306. In some embodiments, the second end 1304 of the connecting portion 1301 can have an annular multi-layer structure, which includes an inner layer 1305, an outer layer 1306, and one or more intermediate layers ( Figure 13B not shown).

[0305] In some embodiments, as Figure 13B As shown, one end of the outer layer 1306 can be connected to the fixing portion 1302 of the connector 1101, and the other end of the outer layer 1306 can be connected to the inner layer 1305. In some embodiments, the inner layer 1305 may not be connected to the fixing portion 1302. In some embodiments, the inner layer 1305 can be connected to the outer surface of the gas outlet 1004 of the gas pressurizing unit 808. In some embodiments, the outer surface of the gas outlet 1004 of the gas pressurizing unit 808 may include one or more protrusions, and the inner surface of the inner layer 1305 may include one or more corresponding grooves to match the one or more protrusions, so that the gas outlet 1004 of the gas pressurizing unit 808 can be fixed to the connector 1101. In some embodiments, the outer surface of the gas outlet 1004 of the gas pressurizing unit 808 may include one or more grooves, and the inner surface of the inner layer 1305 may include one or more corresponding protrusions to match the one or more grooves, so that the gas outlet 1004 of the gas pressurizing unit 808 can be fixed to the connector 1101. The protrusions and / or grooves can have various shapes (e.g., rectangular parallelepiped, cube, cylinder, cone, truncated cone, prism, pyramid, truncated pyramid, etc. or any combination thereof). For example only, Figure 13B As shown, the protrusions and corresponding grooves can be annular. In some embodiments, the protrusions and / or corresponding grooves can be evenly arranged. Alternatively or additionally, the protrusions and / or corresponding grooves can be arranged in a disordered manner. In some embodiments, the outer layer 1306 may include a first annular flexible structure 1307, which is configured to withstand or suppress the vibration of the gas pressurization unit 808 along the axial direction of the connecting portion 1301. In some embodiments, the first annular flexible structure 1307 may have a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, etc. or a combination thereof. In some embodiments, the first annular flexible structure 1307 may have one or more folds.

[0306] In some embodiments, one end of the inner layer 13-05 can be connected to the fixing portion 1302 of the connector 1101, and the other end of the inner layer 1305 can be connected to the outer layer 1306. In some embodiments, the outer layer 1306 may not be connected to the fixing portion 1302. In some embodiments, the outer layer 1306 can be connected to the inner surface of the gas outlet 1004 of the gas pressurizing unit 808. In some embodiments, the inner surface of the gas outlet 1004 of the gas pressurizing unit 808 may include one or more grooves, and the outer surface of the outer layer 1306 may include one or more corresponding protrusions to match the one or more grooves, so that the gas outlet 1004 of the gas pressurizing unit 808 can be fixed to the connector 1101. In some embodiments, the inner surface of the gas outlet 1004 of the gas pressurizing unit 808 may include one or more protrusions, and the outer surface of the outer layer 1306 may include one or more corresponding grooves to match the one or more protrusions, so that the gas outlet 1004 of the gas pressurizing unit 808 can be fixed to the connector 1101. The protrusions and / or grooves can have various shapes (e.g., rectangular parallelepiped, cube, cylinder, cone, truncated cone, prism, pyramid, truncated pyramid, etc. or any combination thereof). For example only, Figure 13B As shown, the protrusions and corresponding grooves may be annular. In some embodiments, the protrusions and / or corresponding grooves may be arranged evenly. Alternatively or additionally, the protrusions and / or corresponding grooves may be arranged disorderly. In some embodiments, the inner layer 1305 may include a first annular flexible structure, which is configured to withstand or suppress the vibration of the gas pressurization unit MZ03-08 along the axial direction of the connecting portion 1301. In some embodiments, the first annular flexible structure may have a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, etc. or a combination thereof. In some embodiments, the first annular flexible structure may have one or more folds.

[0307] In some embodiments, the joint between the inner layer 1305 and the outer layer 1306 may include a second annular flexible structure 1308 configured to withstand or dampen vibrations of the gas pressurizing unit 808 along a radial direction of the connecting portion 1301. In some embodiments, the second annular flexible structure 1308 may have a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or any combination thereof. In some embodiments, the second annular flexible structure 1308 may have one or more folds.

[0308] In some embodiments, if the second end 1304 of the connection portion 1301 has an annular multi-layer structure comprising an inner layer 1305, an outer layer 1306, and one or more intermediate layers, the one or more intermediate layers may comprise a first annular flexible structure configured to withstand or dampen vibrations of the gas pressurizing unit 808 along the axial direction of the connection portion 1301. In some embodiments, the first annular flexible structure may have a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or any combination thereof. In some embodiments, the first annular flexible structure may have one or more folds. In some embodiments, the joint between the inner layer 1305 and the intermediate layer, the joint between the outer layer 1306 and the intermediate layer, and / or the joint between two intermediate layers may comprise one or more second annular flexible structures configured to withstand or dampen vibrations of the gas pressurizing unit 808 along the radial direction of the connection portion 1301. In some embodiments, each second annular flexible structure may have a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or any combination thereof. In some embodiments, each second annular flexible structure may have one or more folds.

[0309] It should be noted that the above description is provided for illustrative purposes only and is not intended to limit the scope of the present disclosure. For those of ordinary skill in the art, various changes and modifications can be made under the teachings of the present disclosure. However, these changes and modifications do not depart from the scope of the present disclosure. In some embodiments, the number of first annular flexible structures may be greater than one. In some embodiments, the number of second annular flexible structures may be greater than one. In some embodiments, the first annular flexible structure, the second annular flexible structure, the inner layer 1305 and / or the outer layer 1306 may be made of the same or different materials. For example, the first annular flexible structure and / or the second annular flexible structure may be made of a material with relatively high elasticity (e.g., a flexible material), while the inner layer 1305 and / or the outer layer 1306 may be made of a material with relatively low elasticity (e.g., a hard material). In some embodiments, the first annular flexible structure, the second annular flexible structure, the inner layer 1305 and / or the outer layer 1306 may have the same or different thicknesses. For example, the first annular flexible structure and / or the second annular flexible structure can have a relatively small thickness, while the inner layer 1305 and / or the outer layer 1306 can have a relatively large thickness. In some embodiments, the first annular flexible structure, the second annular flexible structure, the inner layer 1305 and / or the outer layer 1306 can be partially reinforced by one or more fibers. In some embodiments, the connector 1101 can be manufactured based on 3D printing. In some embodiments, the structure of the connector 1301 can be applied to various connectors of the respiratory ventilation device 110, including, for example: a connector located between the air outlet 111 and the breathing tube 160, a connector located between the main body of the respiratory ventilation device 110 and the liquid chamber, a connector located between the breathing tube 160 and the object interface 170, etc.

[0310] Figure 14A and 14B An exemplary respiratory ventilation device is shown that includes a gas parameter detection assembly according to some embodiments of the present disclosure. The gas parameter detection assembly can be configured to detect one or more gas parameters of (pressurized and / or humidified) respiratory gas downstream from, for example, humidification assembly 220. In some embodiments, the parameters detected by the gas parameter detection assembly can include snoring of a user of respiratory ventilation device 110 (e.g., subject 180). Figure 14A An isometric view of the main body of respiratory ventilation device 110 including a gas parameter sensing assembly is shown. Figure 14B A cross-sectional view of a respiratory ventilation device 110 including a gas parameter detection assembly is shown. In some embodiments, Figure 14A and 14BAs shown, the gas parameter detection assembly may include a collection unit 1401. Collection unit 1401 may be configured to collect airflow. In some embodiments, collection unit 1401 may be positioned downstream of the humidified and pressurized respiratory gas associated with humidification assembly 220. In some embodiments, the airflow may be disrupted by snoring by a user of respiratory ventilation device 110 (e.g., subject 180). In some embodiments, the main body of respiratory ventilation device 110 may include a gas return chamber 1404. Gas return chamber 1404 may be connected to a gas outlet 1402 of respiratory ventilation device 110. In this disclosure, gas outlet 1402 of respiratory ventilation device 110 may also be referred to as the main gas outlet of respiratory ventilation device 110. Gas return chamber 1404 may be configured to direct the (pressurized and humidified) respiratory gas to gas outlet 1402. In some embodiments, collection unit 1401 may be positioned within gas return chamber 1404. In some embodiments, collection unit 1401 may be positioned facing gas outlet 1402 of respiratory ventilation device 110. In some embodiments, the collection portion 1401 can be detachably connected to the respiratory ventilation device 110. In some embodiments, the collection portion 1401 can be fixed to the respiratory ventilation device 110 via one or more slots (e.g., two slots) provided on one or more sides of the collection portion 1401 (see Figure 16B ).

[0311] In some embodiments, as Figure 14A 、 14BAs shown in Figures 16A-16D , the collection portion 1401 may include an inlet 1601, an outlet 1602, and / or at least one channel 1403 (also referred to as a gas channel). In some embodiments, the channel 1403 may be a curved channel. In some embodiments, the channel 1403 may be disposed within the collection portion 1401. In some embodiments, the first end of the channel 1403 may be the inlet 1601. In some embodiments, the inlet 1601 may be located on a first surface (e.g., the front surface) of the collection portion 1401. In some embodiments, the first surface may face the gas outlet 1402 of the respiratory ventilation device 110. In some embodiments, the second end of the channel 1403 may be the outlet 1602. In some embodiments, the outlet 1602 may be located on a second surface (e.g., the bottom surface) of the collection portion 1401. In some embodiments, the second surface may be different from the first surface. In some embodiments, the second surface of the collection portion 1401 may be sealingly connected to an inner surface of the main body of the respiratory ventilation device 110 (e.g., the bottom surface of the gas return chamber 1404). In some embodiments, inlet 1601 may be positioned above gas return chamber 1404. In some embodiments, inlet 1601 may be positioned above the second surface of collection portion 1401. In some embodiments, collection portion 1401 may protrude from the inner surface of the main body of respiratory ventilation device 110 (e.g., the bottom surface of gas return chamber 1404) to prevent water from flowing into collection portion 1401. In some embodiments, the cross-sectional area of ​​channel 1403 may gradually increase from inlet 1601 to outlet 1602. In some embodiments, one or more ports (e.g., first port 1501, second port 1502) are positioned in the interior space below outlet 1602 of collection portion 1401. In some embodiments, airflow may be introduced into the interior space of respiratory ventilation device 110 via collection portion 1401 and the one or more ports. In some embodiments, collection portion 1401 may be made of a flexible material (e.g., silicone) or a rigid material. In some embodiments, collection portion 1401 may be made of a hydrophobic material.

[0312] Figure 15A and 15B 15. The interior space of an exemplary respiratory ventilation device including a gas parameter detection assembly according to some embodiments of the present disclosure is shown. In some embodiments, a printed circuit board (PCB) can be installed in the interior space of the respiratory ventilation device 110. In some embodiments, one or more sensors (e.g., first sensor 1504, second sensor 1505) can be integrated into the PCB. Figure 15A A bottom view of the interior of respiratory ventilator 110 is shown. Figure 15BAn enlarged view of one or more sensors integrated into a printed circuit board (PCB) mounted within the interior space of respiratory ventilation device 110 is shown. Figure 15A and 15B As shown, the gas parameter detection component may include a first sensor 1504. In some embodiments, the first sensor 1504 may be configured to measure a gas parameter associated with snoring based on airflow. In some embodiments, the first sensor 1504 may be configured to detect the pressure of the airflow. In some embodiments, the first sensor 1504 may include a third port 1506 located on its surface. In some embodiments, the third port 1506 may be integrally formed on the surface of the first sensor 1504. In some embodiments, the first sensor 1504 may be a pressure sensor. In some embodiments, the gas parameter detection component may include a first tube (not shown). The first tube may connect the first port 1501 with the third port 1506. The first tube may be configured to direct the airflow from the collection portion 1401 to the surface of the first sensor 1504.

[0313] In some embodiments, first sensor 1504 (e.g., a pressure sensor) can be further configured to detect the pressure of the respiratory gas in one or more gas channels of respiratory ventilation device 110. In some embodiments, the pressure of the respiratory gas in the gas channels of respiratory ventilation device 110 can be detected based on a low-frequency portion of the signal detected by first sensor 1504, while a snoring signal can be detected based on a high-frequency portion of the signal detected by first sensor 1504. In some embodiments, control module 260 can control and / or adjust the rotational speed of gas pressurization unit 210 to achieve a desired pressure of the respiratory gas based on the detected pressure of the respiratory gas.

[0314] In some embodiments, the respiratory ventilation device 110 may include a flow detection assembly. The flow detection assembly may be configured to detect the flow of one or more gases in one or more channels of the respiratory ventilation device 110. In some embodiments, the first sensor and the second sensor may share the same acquisition unit 1401. In some embodiments, the flow detection assembly may include a second sensor 1505. The second sensor 1505 may be configured to detect flow signals associated with one or more gases in one or more channels of the respiratory ventilation device 110. In some embodiments, the second sensor 1505 may be a flow sensor. In some embodiments, the second sensor 1505 may include a fourth port 1507 and / or a fifth port 1508 located on its surface. In some embodiments, the fourth port 1507 and / or the fifth port 1508 may be integrally formed on the surface of the second sensor 1505. In some embodiments, the flow detection assembly may include a sixth port 1503 (also referred to as an auxiliary acquisition port). The sixth port 1503 may be disposed in the body of the respiratory ventilation device 110. In some embodiments, the sixth port 1503 may be positioned upstream of the one or more gases flowing to the collection portion 1401. In some embodiments, the sixth port 1503 may be configured to collect gas flow from the gas outlet port of the gas pressurizing unit 210. In some embodiments, the flow detection assembly may include a second tube (not shown) and / or a third tube (not shown). The second tube may be configured to direct the gas flow from the collection portion 1401 to the surface of the second sensor 1505. In some embodiments, the second tube may connect the second port 1502 with the fourth port 1507 to direct the gas flow from the collection portion 1401 to the surface of the second sensor 1505. The third tube may be configured to direct the gas flow from the auxiliary collection port to the surface of the second sensor 1505. In some embodiments, the third tube may connect the fifth port 1508 with the sixth port 1503 to direct the gas flow from the auxiliary collection port to the surface of the second sensor 1505.

[0315] Figures 16A-16D An exemplary collection unit of a gas parameter detection assembly and / or flow detection assembly according to some embodiments of the present disclosure is shown. Collection unit 1401 can be disposed in the body of respiratory ventilation device 110, facing gas outlet 1402 of respiratory ventilation device 110. In some embodiments, collection unit 1401 can obtain pressurized and humidified respiratory gas from downstream of humidification assembly 220. As a result, the airflow obtained by collection unit 1401 can be more stable, and the detected parameters (e.g., snoring, pressure, flow rate, etc.) can be more accurate. Figure 16A 14 shows a perspective view of a collection portion 1401 according to some embodiments of the present disclosure. Figure 16AAs shown, the collection portion 1401 may have a roughly rounded rectangular parallelepiped structure with six surfaces (e.g., a front surface, a back surface, a top surface, a bottom surface, a left surface, and a right surface). The front surface of the collection portion 1401 may face the gas outlet 14-02 of the respiratory ventilation device 110. In some embodiments, the collection portion 1401 may have another structure including a rectangular parallelepiped, a cube, a cylinder, a prism, etc., or any combination thereof.

[0316] In some embodiments, the collection portion 1401 may include an inlet 1601. In some embodiments, the inlet 1601 may be located on the front surface of the collection portion 1401 facing the gas outlet 1402 of the respiratory ventilation device 110. In some embodiments, the inlet 1601 may be located below the upper edge of the gas outlet 1402 of the respiratory ventilation device 110, but above the lower edge of the gas outlet 1402. In some embodiments, the inlet 1601 may be located in the upper left corner of the front surface. In some embodiments, the inlet 1601 may be located at another location on the front surface. For example, the inlet 1601 may be located in the upper right corner or the center of the front surface. In some embodiments, the inlet 1601 may be located on another surface of the collection portion 1401, such as the top surface of the collection portion 1401. In some embodiments, the inlet 1601 may have the shape of an elongated rounded rectangle (or strip). In some embodiments, the inlet 1601 may have other shapes, including square, circular, polygonal, etc., or any combination thereof. In some embodiments, inlet 1601 can have one or more openings.

[0317] Figure 16B FIG shows a side perspective view of a collection portion 1401 according to some embodiments of the present disclosure. Figure 16BAs shown, the collection portion 1401 may include one or more slots. The one or more slots may be configured to establish a detachable connection between the collection portion 1401 and the main body of the respiratory ventilation device 110. In some embodiments, the one or more slots may include a first securing slot 1602 and a second securing slot 1603. The first securing slot 1602 and the second securing slot 1603 may be located on the same or different surfaces of the collection portion 1401. For example, the first securing slot 1602 may be located on the front surface of the collection portion 1401, while the second securing slot 1603 may be located on the rear surface of the collection portion 1401. In some embodiments, the first securing slot 1602 and the second securing slot 1603 may be located in parallel to secure the collection portion 1401 horizontally. In some embodiments, the first securing slot 1602 and the second securing slot 1603 may be located on the right and left surfaces, respectively. In some embodiments, the first fixing slot 1602 and the second fixing slot 1603 may be disposed closer to the bottom surface of the collecting portion 1401. In some embodiments, the collecting portion 1401 may include a first groove 1605 and a second groove 1606 disposed on any surface of the collecting portion 1401 (eg, the right surface).

[0318] In some embodiments, one or more claws may be provided on the bottom surface of the collection portion 1401. Accordingly, one or more slots connected to the one or more claws may be provided in the body of the respiratory ventilation device 110 to secure the collection portion 1401. In some embodiments, one or more slots may be provided on the bottom surface of the collection portion 1401, and one or more claws connected to the one or more slots may be provided in the body of the respiratory ventilation device 110 to secure the collection portion 1401.

[0319] Figure 16C 1 shows a bottom perspective view of the collection portion 14-01 according to some embodiments of the present disclosure. Figure 16C As shown, the collection portion 1401 may include an outlet 1602. In some embodiments, as shown Figure 16CAs shown, outlet 1602 can be disposed on the bottom surface of collection portion 141. In some embodiments, outlet 1602 can be disposed on another surface of collection portion 1401, such as the rear surface of collection portion 1401. Outlet 1602 can be disposed below inlet 1601. In some embodiments, outlet 1602 can have a rounded rectangular shape. In some embodiments, outlet 1602 can have a square, circular, polygonal, or any combination thereof. In some embodiments, a silicone gasket 1604 can be disposed on collection portion 1401 to ensure a sealed connection between collection portion 1401 and the main body of respiratory ventilation device 110. In some embodiments, silicone gasket 1604 can be disposed around outlet 1602. In some embodiments, outlet 1602 can be disposed closer to the upper edge of silicone gasket 1604.

[0320] Figure 16D FIG shows a side cross-sectional view of the collecting portion 1401 according to some embodiments of the present disclosure. Figure 16D As shown, collection portion 1401 may include channel 1403. Channel 1403 may be disposed within collection portion 1401. Channel 1403 may be configured to connect inlet 1601 and outlet 1602. In some embodiments, channel 1403 may have a relatively small cross-sectional area near inlet 1601 and a relatively large cross-sectional area near outlet 1602. In some embodiments, the cross-sectional area of ​​channel 1403 may gradually increase from inlet 1601 to outlet 1602. In some embodiments, pressurized respiratory gas may include a certain amount of moisture. In some embodiments, condensation of water vapor in the pressurized respiratory gas may generate one or more water droplets near inlet 1601. In some embodiments, to prevent condensed water droplets from flowing from inlet 1601 and channel 1403 onto the surface of first sensor 1504, channel 1403 may include a downward-pointing portion near inlet 1601, such that inlet 1601 is positioned below the top of channel 1403. Therefore, it is possible to prevent condensed water droplets from flowing to the surface of the first sensor through the channel 1403 under the action of gravity.

[0321] In some embodiments, respiratory ventilation device 110 may include a pressure sensor (e.g., first sensor 1504) and an airflow sensor (e.g., second sensor 1505) for detecting snoring, and a humidified gas inlet (e.g., inlet 1601) configured to introduce pressurized and humidified respiratory gas from humidification assembly 220. In some embodiments, the pressure sensor and the airflow sensor may be connected to a portion located between a main gas outlet (e.g., gas outlet 1402) of respiratory ventilation device 110 and the humidified gas inlet via a (tortuous) channel (e.g., channel 1403).

[0322] Figure 17 17 shows an exemplary respiratory ventilation device according to some embodiments of the present disclosure. The respiratory ventilation device 1700 may include a body 1702, and / or a humidification assembly. In some embodiments, the heating assembly may be configured to humidify the pressurized respiratory gas to produce pressurized and humidified respiratory gas. In some embodiments, the humidification assembly may include a liquid chamber 1704, a heating plate 1710, and a heat conducting plate 1810 (see FIG. 17 ). Figure 18A and 18B Liquid chamber 1704 can be configured to contain one or more liquids (e.g., water and / or medication). The thermally conductive plate can be configured to conduct heat from heating plate 1710 to heat the one or more liquids and generate vapor to humidify the pressurized respiratory gas. In some embodiments, the thermally conductive plate can be disposed at the bottom of liquid chamber 1704. In some embodiments, the thermally conductive plate can include a metal thermally conductive material.

[0323] In some embodiments, the body 1702 may include a gas pressurization unit ( Figure 17 ), gas inlet 1706, gas outlet 1708 and / or support plate 1707. In some embodiments, the gas inlet 1706 and / or gas outlet 1708 can be disposed at a first interface between the body 1702 and the liquid chamber 1704. In some embodiments, the support plate 1707 can be disposed at a second interface between the body 1702 and the liquid chamber 1704. In some embodiments, the support plate 1707 can be fixed to a substrate of the body 1702. In some embodiments, the first interface between the body 1702 and the liquid chamber 1704 (see Figures 23A-23D ) may refer to the side surface of the body 1702 and the corresponding side surface of the liquid chamber 1704. In some embodiments, the second interface between the body 1702 and the liquid chamber 1704 (see Figure 17-21D ) can refer to the bottom surface of the liquid chamber 1704 and the corresponding surface of the support plate 1707 of the main body 1702. In some embodiments, the gas outlet 1708 can be configured to discharge the pressurized breathing gas from the main body 1702 to the liquid chamber 1704. In some embodiments, the gas inlet 1706 can be configured to direct the pressurized and humidified breathing gas from the liquid chamber 1704 back into the main body 1702. In some embodiments, the support plate 1707 may include a first hole 1709 and / or a second hole 1711. In some embodiments, the first hole 1709 and / or the second hole 1711 can be disposed on the second interface. In some embodiments, at least a portion of the heating plate 1710 can be disposed in the second hole 1711.

[0324] The heating plate 1710 can be configured to heat one or more liquids in the liquid chamber 1704 and / or generate vapor to humidify the pressurized breathing gas. In some embodiments, the heating plate 1710 can be mounted on the base of the body 1702 by one or more springs 2202 (see Figure 22C ). The heating plate 1710 can move up and down through the second hole 1711 when driven by pressure or when the pressure is released.

[0325] In some embodiments, the liquid chamber 1704 can be detachably connected to the body 1702, so that the humidification assembly can be detachably connected to the body 1702. For example, the liquid chamber 1704 can be detachably connected to the body 1702 by a push-push mechanism (see Figure 19-21D ) is detachably connected to the main body 1702 via a hole (e.g., first hole 1709) of the support plate 1707. If the liquid chamber 1704 is mounted on the main body 1702 of the respiratory ventilation device 1700, the bottom of the liquid chamber 1704 (e.g., the heat conducting plate of the liquid chamber 1704) can be in close contact with the heating plate 1710. More description of the humidification assembly can be found in other parts of this disclosure (e.g., Figure 18A and 18B and its description).

[0326] Figure 18A and 18B An exploded view of an exemplary liquid chamber according to some embodiments of the present disclosure is shown. Figure 18A and 18B As shown, the liquid chamber 1704 may include a box cover and a box body. In some embodiments, the box cover may include a cover shell 1802 and one or more gas channels 1805. In some embodiments, the box body may include a box shell 1808, a heat conducting plate sealing gasket 1809, and a heat conducting plate 1810. It should be noted that in some embodiments, the gas channel 1805 may be provided in the box. In some embodiments, the liquid chamber 1704 may include a fixing gasket 1806 and / or a box cover sealing gasket 1807 located between the box body and the box cover. The fixing gasket 1806 and / or the box cover sealing gasket 1807 may be configured to achieve a sealed connection between the box body and the box cover. In some embodiments, the liquid chamber 1704 may include a connecting plate 1803 and / or a gas channel sealing gasket 1804 to cooperate with the main body 1702.

[0327] In some embodiments, the components of liquid chamber 1704 may be detachably connected. For example, connecting plate 1803 may be disposed and / or secured to cover 1802 by bonding, riveting, mortising, clamping, meshing, or any combination thereof. As another example, gas channel sealing gasket 1804 may be connected and / or secured to gas channel 1805. As another example, retaining gasket 1806 and / or lid sealing gasket 1807 may be disposed and / or secured to cover 1808 to improve the airtightness between cover 1802 and cover 1808. In some embodiments, retaining gasket 1806 may be disposed within lid sealing gasket 1807. As another example, heat conducting plate sealing gasket 1809 may be disposed between heat conducting plate 1810 and the bottom frame of cover 1808. As yet another example, heat conducting plate 1810 may be connected to heat conducting plate sealing gasket 1809 by bonding, riveting, mortising, clamping, meshing, or any combination thereof. As yet another example, the heat conducting plate sealing gasket 1809 can be secured to the bottom frame of the tank shell 1808 by bonding, riveting, mortising, clamping, meshing, or the like, or any combination thereof.

[0328] Figure 19 An exemplary push-push mechanism connected to a liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure is shown. In some embodiments, push-push mechanism 1904 can be disposed below support plate 1707. In some embodiments, housing 1808 of liquid chamber 1704 can be removably connected to push-push mechanism 1904 via push rod 1906. In some embodiments, push rod 1906 can be disposed below the bottom surface of liquid chamber 1704.

[0329] In some embodiments, liquid chamber 1704 can be driven by a first thrust. When the first thrust is released, push rod 1906 can lock with push-push mechanism 1904, allowing liquid chamber 1704 to be mounted on body 1702 of respiratory ventilation device 1700. If liquid chamber 1704 is driven by a second thrust, and when the second thrust is released, push rod 1906 can be removed from push-push mechanism 1904, allowing liquid chamber 1704 to be released from body 1702 of respiratory ventilation device 1700. In some embodiments, the direction of the first thrust can be the same as the direction of the second thrust. For example, the direction of the first thrust and the direction of the second thrust can be vertically downward. In some embodiments, push-push mechanism 1904 can be positioned on the side of the first interface between body 1702 and liquid chamber 1704, so that the first thrust and the second thrust can be in horizontal directions.

[0330] Figure 20A and 20B An exemplary push-push mechanism according to some embodiments of the present disclosure is shown. Figure 20AAn axonometric view of the push-push mechanism 1904 is shown. Figure 20B An exploded view of the push-push mechanism 1904 is shown. In some embodiments, as Figure 20A and 20B As shown, the push-push mechanism 1904 may include a guide groove 2002, a slider 2004, a first spring 2006, a second spring 2008 and a push rod 1906 (see Figure 19 )wait.

[0331] The guide groove 2002 can be configured to accommodate the first spring 2006 and the second spring 2008 and guide the movement of the slider 2004. In some embodiments, the guide groove 2002 can be disposed on the main body (e.g., main body 1702) of the respiratory ventilation device 1700. For example, the guide groove 2002 can be disposed below the support plate 1707 of the main body (e.g., main body 1702) of the respiratory ventilation device 1700. In some embodiments, the guide groove 2002 can be secured to the main body (e.g., main body 1702) by bonding, riveting, mortising, clamping, meshing, or the like, or any combination thereof. In some embodiments, the guide groove 2002 can be made of a material such as cast iron, stainless steel, non-ferrous metal, plastic, or the like, or any combination thereof.

[0332] The slider 2004 can be mounted on the guide slot 2002. In some embodiments, the slider 2004 can move forward and backward along the guide slot 2002 in a first direction. In some embodiments, the first direction can be parallel to the guide slot 2002. In some embodiments, the slider 2004 can include a guide block 2005. The guide block 2005 can be configured to guide or limit the movement position of the push rod 1906. In some embodiments, as Figure 20A and 20BAs shown, guide block 2005 may have a frame similar to the character A. In some embodiments, guide block 2005 may include a frame different from the character A (e.g., a frame for the character N or M, etc.). In some embodiments, guide block 2005 may include a first inclined surface 2015, a groove 2035, a second inclined surface 2025, and a third inclined surface 2055. In some embodiments, third inclined surface 2055 may be substantially vertical. In some embodiments, the inclination direction of first inclined surface 2015 may be different from the inclination direction of second inclined surface 2025. In some embodiments, the first angle between first inclined surface 2015 and the vertical direction may be greater than the second angle between second inclined surface 2025 and the vertical direction. First inclined surface 2015, second inclined surface 2025, and / or third inclined surface 2055 may be configured to guide the movement of push rod 1906. Groove 2035 may be configured to limit the movement of push rod 1906. In some embodiments, guide block 2005 may include a first protrusion 2065, a second protrusion 2075, and / or a third protrusion 2085. First protrusion 2065 and / or second protrusion 2075 may be configured to prevent push rod 1906 from moving out of groove 2035 when liquid chamber 1704 is mounted on body 1702, thereby securing liquid chamber 1704 to body 1702. In some embodiments, first protrusion 2065 and / or second protrusion 2075 may be sharp. In some embodiments, the bottom end of first protrusion 2065 may be lower than the bottom end of second protrusion 2075. In some embodiments, first protrusion 2065 and second protrusion 2075 may be located on the same side of third protrusion 2085 in a horizontal direction.

[0333] In some embodiments, the slider 2004 may further include a protrusion 2045 (or bump) positioned below the groove 2035 of the guide block 2005. The protrusion 2045 may include a first inclined surface and a second inclined surface. The first inclined surface of the protrusion 2045 may be adjacent to the first inclined surface of the guide block 2005. The second inclined surface of the protrusion 2045 may be adjacent to the second inclined surface of the guide block 2005. In some embodiments, the groove 2035 may cooperate with the protrusion 2045 to limit the movement of the push rod 1906. In some embodiments, the slider 2004 may be made of a material such as cast iron, stainless steel, non-ferrous metal, plastic, or any combination thereof. In some embodiments, the material of the slider 2004 may be the same as or different from the material of the guide groove 2002.

[0334] A first spring 2006 and a second spring 2008 can be disposed in guide slot 2002. First spring 2006 can include a first end and a second end. The first end of first spring 2006 can be connected to the first end of guide block 2005. The second end of first spring 2006 can be secured to the main body (e.g., main body 1702) of respiratory ventilation device 1700. Second spring 2008 can include a first end and a second end. The first end of second spring 2008 can be connected to the second end of guide block 2005. The second end of second spring 2008 can be secured to the main body (e.g., main body 1702) of respiratory ventilation device 1700. In some embodiments, first spring 2006 can be the same as or different from second spring 2008 in terms of, for example, material (e.g., carbon steel or alloy steel), type (e.g., coil spring, wave spring, shaped spring, or conical spring), size, etc., or any combination thereof.

[0335] In some embodiments, the first spring 2006 and the second spring 2008 can be configured to guide the moving direction of the guide block 2005 (or the slider 2004). In some embodiments, if the guide block 2005 (or the slider 2004) is driven in a first direction (e.g. Figure 20B The compressed second spring 2008 can drive the guide block 2005 (or the slider 2004) to move in the opposite direction of the first direction (for example, Figure 20B ). Additionally or alternatively, if guide block 2005 (or slider 2004) is driven to move in a direction opposite to the first direction, first spring 2006 may be compressed. The compressed first spring 2006 can drive guide block 2005 (or slider 2004) to move in the first direction. In some embodiments, first spring 2006 may be omitted.

[0336] In some embodiments, push rod 1906 may include a first end and a second end. The first end of push rod 1906 may be mounted on liquid chamber 1704 (e.g., housing 1808). The second end of push rod 1906 may cooperate with guide block 2005. In some embodiments, push rod 1906 may move back and forth along a second direction. In some embodiments, the second direction may be perpendicular to the first direction of movement of guide block 2005 (or slider 2004). In some embodiments, the second end of push rod 1906 may include a fixed structure, such as a protrusion (e.g., a cylinder). In some embodiments, the second end of push rod 1906 may include a rotatable structure, such as a bearing assembly. In some embodiments, the second end of push rod 1906, including the fixed structure, can slide along first inclined surface 2015, third inclined surface 2055, groove 2035, and second inclined surface 2025 of guide block 2005. In some embodiments, the second end of the bolt 1906 including the rotatable structure can roll along the first inclined surface 2015 , the third inclined surface 2055 , the groove 2035 , and the second inclined surface 2025 of the guide block 2005 .

[0337] Figure 21A and 21B An exemplary process for mounting a liquid chamber on a body of a respiratory ventilation device using a push-push mechanism according to some embodiments of the present disclosure is shown. Figure 21AAs shown, liquid chamber 1704 can be driven by a first thrust and then mounted on body 1702. In some embodiments, the first thrust can be generated by a user (e.g., subject 180). The direction of the first thrust can be indicated by arrow A (e.g., vertical direction, also referred to as the second direction). In some embodiments, push rod 1906 can pass through first hole 1709 and interact with guide block 2005. In some embodiments, in its natural state, the center of push rod 1906 can be located to the right of the bottom of second protrusion 2075 along the first direction. When driven by the first thrust, push rod 1906 can move along the second direction (indicated by arrow A) with liquid chamber 1704 and slide downward along first inclined surface 2015 of guide block 2005. Therefore, when push rod 1906 moves downward, it can push guide block 2005 to move in the first direction (indicated by arrow B) and compress second spring 2008. At the same time, the compressed second spring 2008 can generate a reaction force that causes the push rod 1906 to be pressed by the guide block 2005. In some embodiments, the first direction can be substantially perpendicular to the second direction. In some embodiments, if the first thrust is greater than the reaction force, the push rod 1906 can slide downward along the third inclined surface 2055 and move to or near the bottom edge of the third inclined surface 2055. The push rod 1906 can then separate from the first inclined surface and / or the third inclined surface 2055 and reach below the bottom of the first protrusion 2065.

[0338] In some embodiments, if the first pushing force is released, the push rod 1906 may move in a direction opposite to the second direction, and the push rod 1906 may slide in the left portion of the area formed by the protrusion 2045 and the groove 2035 of the guide block 2005. At the same time, the guide block 2005 may move in a direction opposite to the first direction. When the push rod 1906 moves to the top position of the groove 2035, the push rod 1906 and the guide block 2005 may stop moving, and thus the push rod 1906 may be inserted into the groove 2035 of the guide block 2005 (see FIG. 2 ). Figure 21B ). Thus, the liquid chamber 1704 can be mounted on the main body 1702 of the respiratory ventilation device. In some embodiments, when a first thrust is applied to the liquid chamber 1704 and / or when the liquid chamber 1704 is mounted on the main body 1702, the heating plate 1710 can be pressed by the bottom surface of the liquid chamber 1704 and can move downward in the second hole 1711. In some embodiments, one or more springs 2202 located below the heating plate 1710 can be pressed, and then the heating plate 1710 and the heat conducting plate 1810 located at the bottom of the liquid chamber 1704 can form close contact (or tight contact).

[0339] Figure 21C and21D An exemplary process for removing a liquid chamber from a body of a respiratory ventilation device using a push-push mechanism according to some embodiments of the present disclosure is shown. Figure 21C As shown, liquid chamber 1704 can be driven by a second thrust and then released from body 1702. In some embodiments, the second thrust can be generated by a user (e.g., object 180). The direction of the second thrust can be indicated by arrow A (e.g., vertical direction, also referred to as the second direction). When driven by the second thrust, push rod 1906 can move along the second direction (indicated by arrow A) together with liquid chamber 1704 and move downward in the right part of the area formed by protrusion 2045 and groove 2035 of guide block 2005. At the same time, guide block 2005 can move in the opposite direction of the first direction (indicated by arrow B'). In some embodiments, the movement of guide block 2005 in the opposite direction of the first direction can be driven by the reaction force of second spring 2008. Then, push rod 1906 can be released from groove 2035 and can reach below the bottom of second protrusion 2075.

[0340] In some embodiments, if the second thrust is released, one or more compressed springs 2202 below the heating plate 1710 can drive the heating plate 1710 to move in a direction opposite to the second direction. This movement of the heating plate 1710 can drive the liquid chamber 1704 to move in a direction opposite to the second direction, and this movement of the liquid chamber 1704 can cause the guide push rod 1906 to move in a direction opposite to the second direction. The push rod 1906 can then move along the second inclined surface of the guide block 2005, and the guide block 2005 can move in a direction opposite to the first direction (indicated by arrow B'). As a result, the liquid chamber 1704 can be released from the main body 1702 of the respiratory ventilation device 1700 (see Figure 21D ), and the liquid chamber 1704 can be removed from the body 1702.

[0341] It should be noted that the above description of the push-push mechanism 1904 is provided for illustrative purposes only and is not intended to limit the scope of the present disclosure. A person of ordinary skill in the art may make various changes and modifications based on the teachings of the present disclosure. However, such changes and modifications do not depart from the scope of the present disclosure. In some embodiments, the push-push mechanism 1904 may be mounted on the body 1702 of the respiratory ventilation device in different orientations, and therefore different push forces may be required to install and / or remove the liquid chamber 1704 from the body 1702. In some embodiments, the guide block 2005 may be configured to Figures 20A-21DThe guide block 2005 shown in FIG is mirror-image symmetrical. In some embodiments, the push-push mechanism 1904 may include more than one push rod. In some embodiments, the push-push mechanism 1904 may be configured to unlock the liquid chamber 1704 from the main body of the respiratory ventilation device 110 by pushing the liquid chamber 1704 in a pushing direction. The pushing direction may be substantially perpendicular to the liquid level in the liquid chamber 1704. In some embodiments, the push-push mechanism 1904 may be configured to form an energy storage device that stores energy from the pushing action and releases the stored energy after unlocking the liquid chamber 1704 by applying a force substantially opposite the pushing direction. It should be noted that in some embodiments, the lid of the liquid chamber 1704 may be configured to be closed by pushing in the pushing direction. In some embodiments, the lid of the liquid chamber 1704 may be configured to be opened by pulling in a direction substantially opposite the pushing direction. In some embodiments, during operation of the respiratory ventilation device 110, a user can connect the humidification assembly (e.g., liquid chamber 1704) to the main body of the respiratory ventilation device 110 by pushing the liquid chamber 1704 in the pushing direction, and / or unlock the humidification assembly from the main body by substantially pushing the liquid chamber 1704 in the pushing direction. In some embodiments, before performing the connection operation, the user can place the humidification assembly on a surface of the respiratory ventilation device 110. In some embodiments, the connection operation of the humidification assembly can include locking the housing cover to the housing by pushing the housing cover substantially in the pushing direction.

[0342] Figures 22A-22C 2204 (e.g., Figure 22D ), which is configured to secure one or more springs 2202 (e.g. Figure 22C and 22D Accordingly, the base plate 2203 of the main body 1702 may include one or more fixing posts or bolts configured to fix the second ends of the springs 2202. Thus, the heating plate 1710 may be mounted or fixed to the base plate 2203 of the main body 1702 via one or more springs 2202. Figure 17As shown, the heating plate 1710 can move up and down through the second hole 1711 when driven by pressure or when the pressure is released. In order to facilitate the movement of the heating plate 1710 in the second hole 1711, the heating plate 1710 may include one or more guide protrusions 2201. For example, the heating plate 1710 may include a guide protrusion 2201 on each side of the heating plate 1710. Accordingly, the sidewall of the second hole 1711 may include one or more guide grooves (not shown). The guide protrusions and guide grooves may be configured to guide the movement of the heating plate 1710 and / or limit the position of the heating plate 1710. For example, the second hole 1711 may include a guide groove in each of its side walls. It should be noted that in some embodiments, the heating plate 1710 may include one or more guide grooves, and the second hole 1711 may include one or more guide protrusions corresponding to the guide grooves.

[0343] Figures 23A-23D An exemplary connection between a liquid chamber and a body of a respiratory ventilation device is shown, according to some embodiments of the present disclosure. Figure 23A The figure shows an axonometric view of a connector 2301 that is connected to a tank cover 2302 of a liquid chamber 2303. It should be noted that the cover housing of the tank cover 2302 is not shown for illustration purposes. Figure 23A FIG23B shows an axonometric view of the connector 2301. FIG23B shows an axonometric view of the connector 2301. Figure 23C An axonometric view of the tank cover 2302 is shown. Figure 23D A cross-sectional view of the sealed connection between the gasket 2305 of the connector 2301 and the tank cover 2302 is shown.

[0344] The connector 2301 can be configured to provide a sealed connection between the case cover 2302 and the body of the respiratory ventilation device 110, thereby ensuring airtightness of the pressurized breathing gas flowing between the liquid chamber 2303 and the body of the respiratory ventilation device 110. In some embodiments, the connector 2301 can be fixed to the body of the respiratory ventilation device 110. In some embodiments, the connector 2301 can be detachably connected to the body of the respiratory ventilation device 110. In some embodiments, the housing of the body of the respiratory ventilation device 110 can include a space (e.g., chamber 2502) for accommodating the connector 2301. In some embodiments, the connector 2301 and the body can be a unitary piece. In some embodiments, if the liquid chamber 2303 is fixed to a support plate (e.g., Figure 172302 and the housing of the liquid chamber 2303 are closed, the connector 2301 can provide a sealed connection between the housing cover 2302 and the main body of the respiratory ventilation device 110. In some embodiments, the connector 2301 can be fixed or mounted on the housing cover 2302. In some embodiments, the connector 2301 can be removably connected to the housing cover 2302. In some embodiments, the housing cover 2302 can include a space for mounting the connector 2301. In some embodiments, the connector 2301 and the housing cover 2302 can be integral.

[0345] like Figure 23BAs shown, connector 2301 may include a support frame 2304 and / or a gasket 2305. Support frame 2304 may be configured to support gasket 2305 and / or facilitate securing gasket 2305 to the main body of respiratory ventilation device 110. In some embodiments, gasket 2305 may include an inclined surface. In some embodiments, the inclined surface of connector 2301 (or gasket 2305) may be at an angle to a horizontal plane. In some embodiments, the angle may be substantially within a range of 0 to 90 degrees (e.g., within a range of 30 to 60 degrees). Gasket 2305 may be configured to form a sealed connection between cover 2302 and the main body of respiratory ventilation device 110. In some embodiments, gasket 2305 may include a first hole 2306 and / or a second hole 2307 disposed on the inclined surface. In some embodiments, support frame 2304 may include at least one gas flow channel connected to first hole 2306 and / or second hole 2307. Each of the at least one gas flow channel can be connected to one or more gas channels of the main body of respiratory ventilation device 110. In some embodiments, the edge of first hole 2306 can form a first protrusion 2311. In some embodiments, the edge of second hole 2307 can include a second protrusion 2312. The first protrusion 2311 and / or the second protrusion 2312 can protrude into the case lid 2302. The first protrusion 2311 and / or the second protrusion 2312 can facilitate a sealed connection between connector 2301 and case lid 2302. In some embodiments, the cross-section of the first protrusion 2311 and / or the second protrusion 2312 can have a C-shape, an S-shape, an O-shape, a V-shape, an M-shape, an N-shape, a Z-shape, a U-shape, one or more folds, or a combination thereof. In some embodiments, the first protrusion 2311 and / or the second protrusion 2312 can be made of a soft material (e.g., silicone, soft glue, or any combination thereof). In some embodiments, the first protruding structure 2311 and / or the second protruding structure 2312 can be made of the same material as the gasket 2305. In some embodiments, the first protruding structure 2311 and / or the second protruding structure 2312 can be made of a material different from the material of the gasket 2305. In some embodiments, the thickness of the first protruding structure 2311 and / or the second protruding structure 2312 can be less than the thickness of the gasket 2305.

[0346] In some embodiments, the gasket 2305 can be fixed to the main body of the respiratory ventilation device 110 (e.g., the support frame 2304 of the connector 2301). In some embodiments, the gasket 2305 can be detachably connected to the main body of the respiratory ventilation device 110 (e.g., the support frame 2304 of the connector 2301) by, for example, gluing, bonding, bolting, or the like, or a combination thereof. In some embodiments, the support frame 2304 can be made of a rigid plastic material. Exemplary rigid plastic materials can include acrylonitrile butadiene styrene (ABS) resin material, polyoxymethylene (POM) plastic material, polystyrene (PS) plastic material, polymethyl methacrylate (PMMA) plastic material, polycarbonate (PC) plastic material, poly(ethylene terephthalate) (PET) plastic material, poly(butylene terephthalate) (PBT) plastic material, poly(phenylene oxide) (PPO) plastic material, or any combination thereof. In some embodiments, gasket 2305 can be made of a resilient material, such as an elastomer, a rubber (e.g., silicone), or a combination thereof. In some embodiments, gasket 2305 can include a protruding edge at the interface of support frame 2304 and gasket 2305. The protruding edge of gasket 2305 can facilitate a sealed connection between connector 2301 and the body of respiratory ventilation device 110.

[0347] like Figures 23A-23D As shown, the inclined surface of the gasket 2305 can face the corresponding inclined surface of the connecting plate 2308 of the box cover 2302. The box cover 2302 may include a gas inlet 2309 and a gas outlet 2310. The first hole 2306 located on the inclined surface of the gasket 2305 can correspond to the gas inlet 2309 of the box cover 2302, and the second hole 2307 located on the inclined surface of the gasket 2305 can correspond to the gas outlet 2310 of the box cover 2302. In some embodiments, if the liquid chamber 2303 is fixed to a support plate (e.g., a support plate) of the main body of the respiratory ventilation device 110, Figure 17 1707) and the housing cover 2302 is closed with the housing of the liquid chamber 2303. The housing cover 2302 can be sealed with the main body of the respiratory ventilation device 110 via a gasket 2305. A first hole 2306 of the gasket 2305 and a gas inlet 2309 of the housing cover 2302 can introduce pressurized respiratory gas from the main body of the respiratory ventilation device 110 into the liquid chamber 2303. A second hole 2307 of the gasket 2305 and a gas outlet 2310 of the housing cover 2302 can introduce the humidified and pressurized respiratory gas from the liquid chamber 2303 back into the main body of the respiratory ventilation device 110.

[0348] like Figure 23DAs shown, if the case cover 2302 is closed, the first protruding structure 2311 may be squeezed and deformed, and then may form a closed line contact with the connecting plate 2308 of the case cover 2302 (e.g., around the edge of the gas inlet 2309 and / or the gas outlet 2310). Therefore, the airtightness of the respiratory gas flowing between the main body of the respiratory ventilation device 110 and the liquid chamber 2303 can be ensured.

[0349] Figure 24 Another exemplary connection between a liquid chamber and a body of a respiratory ventilation device according to some embodiments of the present disclosure is shown. Figure 24 As shown, the liquid chamber 2403 may include a housing 2401 and a lid 2402. The connector 2301 may be configured to provide a sealed connection between a portion of the housing 2401 and the main body of the respiratory ventilation device 110. In some embodiments, the connector 2301 may not directly contact the lid 2402. Therefore, the state of the lid 2402 (open or closed) may not affect the connection between the connector 2301 and the housing 2401. In some embodiments, the lid 2402 can be opened using a handle 2404. The handle 2404 may have one or more notches that make the handle 2404 easier to operate. In some embodiments, the lid 2402 may be a sliding cover. In some embodiments, the lid 2402 can slide horizontally or at an angle (e.g., 10 degrees, 20 degrees, 30 degrees, etc.) relative to the horizontal. In some embodiments, to ensure a sealed connection between the box body 2401 and the box cover 2402 , a sealing material (or elastic material) such as silicone may be provided at the interface 2405 between the box body 2401 and the box cover 2402 .

[0350] Figure 25 An exemplary connector secured to a body of a respiratory ventilation device according to some embodiments of the present disclosure is shown. Figure 25As shown, a protruding platform 2501 can be provided at the gas outlet of a noise reduction box (e.g., noise reduction box 801) or in the gas channel between the gas outlet of the noise reduction box and the connector 2301. In some embodiments, the protruding platform 2501 can include a gas channel corresponding to the gas outlet. In some embodiments, the gas channel between the gas outlet of the noise reduction box and the connector 2301 can form a chamber 2502. The chamber 2502 may include a bottom surface. In some embodiments, if the gas outlet of the protruding platform 2501 is in a vertical direction, the upper edge of the protruding platform 2501 can be set to be higher than the bottom surface of the chamber 2502. In some embodiments, if the gas outlet of the protruding platform 2501 is in a horizontal direction, the lower edge of the gas channel in the protruding platform 2501 can be set to be higher than the bottom surface of the chamber 2502. In some cases, if the respiratory ventilation device 110 is tilted (i.e., the liquid chamber is tilted), a certain amount of liquid in the liquid chamber (e.g., liquid chamber 1704, liquid chamber 2403) may accidentally flow out of the liquid chamber and / or the connector 2301 through the gas inlet (e.g., gas inlet 2309) and / or gas outlet (e.g., gas outlet 2310) of the liquid chamber and into the chamber 2502 of the main body of the respiratory ventilation device 110. In some embodiments, the protruding platform 2501 can prevent liquid from entering or reaching the interior space of the main body of the respiratory ventilation device, the detection module 250, the noise reduction assembly 240, and / or the gas pressurization unit 210.

[0351] In some embodiments, the protruding platform 2501 can be fixed to the gas outlet of the noise reduction assembly 240, the gas pressurizing unit 210, or can be fixed in the chamber 2502. In some embodiments, the protruding platform 2501 can be detachably connected to the gas outlet of the noise reduction assembly 240, the gas pressurizing unit 210, or the chamber 2502 via a detachable connection structure (e.g., a threaded structure, a groove structure, a snap-fit ​​joint structure, etc., or any combination thereof).

[0352] Figures 26A-26C An exemplary connection between a body and a liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure is shown. The connector 2601 can be configured to provide a sealed connection between the box cover 2603 and the body 2602 of the respiratory ventilation device 110. In some embodiments, the connector 2601 can include a first threaded hose 2601a and / or a second threaded hose 2601b. The hollow hole of the first threaded hose 2601a can form a gas outlet for the body 2602. The hollow hole of the second threaded hose 2601b can form a gas inlet for the body 2602. In some embodiments, the first threaded hose 2601a and / or the second threaded hose 2601b can be made of an elastic material, including, for example, an elastomer, a rubber (e.g., silicone), etc. or a combination thereof.

[0353] In some embodiments, the tank cover 2603 of the liquid chamber may include a connecting plate 2606 equipped with a gas inlet 2604 and / or a gas outlet 2605 of the tank cover 2603. The gas outlet of the main body 2602 may correspond to the gas inlet 2604 of the tank cover 2603. The gas inlet of the main body 2602 may correspond to the gas outlet 2605 of the tank cover 2603. In some embodiments, as Figure 26A As shown, the hollow holes of the first and second threaded hoses 2601a, 2601b of the connector 2601 can be arranged substantially vertically at a first interface between the main body 2602 and the liquid chamber of the respiratory ventilation device 110. Accordingly, the connecting plate 2606 can be arranged substantially horizontally on the case cover 2603. Therefore, when the case cover 2603 is closed, a sealed connection can be formed between the main body 2602 and the liquid chamber of the respiratory ventilation device 110 via the connector 2601.

[0354] Figure 27 FIG. 2 shows an exemplary connection between the connector 2601 and the connecting plate 2606 of the box cover 2603 when the box cover 2603 is closed according to some embodiments of the present disclosure. Figure 27 As shown, if the box cover 2603 is closed, the connector 2601 can be connected to the connecting plate 2606 of the box cover 2603 and can form a closed line contact with the connecting plate 2606, which can ensure the airtightness of the pressurized breathing gas flowing between the liquid chamber and the main body of the respiratory ventilation device 110.

[0355] Figures 28A-28E An exemplary threaded hose of a connector according to some embodiments of the present disclosure is shown. In some embodiments, the threaded hose of the connector may include one or more corrugated structures on its sidewall. The one or more corrugated structures may be any shape, such as a quarter circle, a semicircle, an arc, a groove, a U-shape, a V-shape, a Z-shape, an M-shape, an S-shape, a C-shape, an O-shape, or any combination thereof. When the lid 2603 is closed, the one or more corrugated structures may provide the connector with a certain degree of elasticity, thereby forming a closed line contact with the lid 2603.

[0356] In some embodiments, one or more curved structures may be present at the top edge of the threaded hose of the connector, and the curved structures may have, for example, a circular, annular, arcuate, crescent, oblique, grooved, U-shaped, V-shaped, Z-shaped, M-shaped, S-shaped, C-shaped, O-shaped, etc., or any combination thereof. The one or more curved structures may enable the connector to form one or more closed-line contacts with the tank cover 2603, thereby ensuring airtightness of the pressurized breathing gas flowing between the liquid chamber and the main body of the respiratory ventilation device 110.

[0357] For example, in Figure 28AIn the embodiment, the threaded hose of the connector may have a two-layer corrugated structure on its side wall. Figure 28B In the embodiment, the threaded hose of the connector may include a quarter-circular pleated structure 2801 near the top edge of the threaded hose and an arc-shaped pleated structure 2802 near the bottom of the threaded hose. In some embodiments, the quarter-circular pleated structure 2801 and / or the arc-shaped pleated structure 2802 may be provided on the inner surface of the threaded hose. In some embodiments, the threaded hose may include an S-shaped curved structure (not shown) located on its top edge. Figure 28C In the embodiment, the threaded hose may include a double C-shaped curved structure 2804 located on its top edge. When the box cover is closed, the double C-shaped curved structure 2804 may form two closed line contacts between the connector and the box cover. Figure 28D In the embodiment, the threaded hose may include an approximately circular structure 2805 located on its top edge. Figure 28E In the embodiment, the threaded hose includes a crescent-shaped curved structure 2806. When the box cover is closed, the approximately circular structure 2805 and the crescent-shaped curved structure 2806 can provide a sealed closed line contact between the connector and the box cover. Figure 1 In some embodiments, the spiral hose may include a bend structure (not shown) in the shape of a slanted line on its top edge and a trapezoidal groove (not shown) on its inner surface. All of the above-mentioned spiral hoses can be configured to ensure airtightness of pressurized breathing gas flowing between the liquid chamber and the main body of the respiratory ventilation device 110.

[0358] Figures 29A-29D An exemplary base plate of a respiratory pressure therapy device 110 is shown, according to some embodiments of the present disclosure. Figure 29A The outer surface of substrate 2900 is shown. Figure 29B Indicates the inner surface of the substrate 2900. Figure 29C A side cross-sectional view of substrate 2900 is shown. Figure 29D 29. An enlarged view of one or more holes 2920 provided on a substrate 2900 is shown. The one or more holes 2920 may be configured to discharge liquid from a liquid chamber (e.g., Figure 17 In some embodiments, during the process of adding liquid to the liquid chamber or in other circumstances (e.g., if the respiratory ventilation device 110 is tilted (i.e., the liquid chamber is tilted), or the liquid chamber is not hermetically sealed), a certain amount of liquid may leak from the liquid chamber onto the base plate 2900 located below the liquid chamber. The leaked liquid can flow out of the respiratory ventilation device 110 through the hole 2920. Therefore, the leaked liquid will not accumulate on the base plate 2900. Figure 29C and Figure 29DAs shown, each of the one or more holes 2920 can have a stepped cross-section. In some embodiments, holes 2920 can facilitate drainage of leaked liquid. In some embodiments, holes 2920 can prevent foreign matter (e.g., a finger of subject 180) from entering respiratory ventilation device 110. In some embodiments, one or more holes 2920 can conform to international standards to enhance the overall appearance of respiratory ventilation device 110 and / or prevent subject 180 from directly viewing the interior of respiratory ventilation device 110 from the outside.

[0359] Figure 30A and 30B An exemplary liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure is shown. Figure 30A and 30B Schematic diagrams showing the liquid chamber 3000 in the open mode from different views are shown. Figure 30A and 30B As shown, the liquid chamber 3000 may include a housing 3002 and a lid 3004. In some embodiments, the lid 3004 may be pivotally connected to the housing 3002 via a connection mechanism. In some embodiments, the liquid chamber 3000 may be opened from the front surface of the respiratory ventilation device 110.

[0360] The housing 3002 can be configured to hold one or more liquids (e.g., water and / or medication). In some embodiments, the housing 3002 can include an opening for filling at least one of the one or more liquids. In some embodiments, the opening can be opened by opening the housing lid 3004 and / or closed by closing the housing lid 3004. In some embodiments, the humidification assembly 220 and the main body of the respiratory ventilation device 110 can be fluidically connected by closing the housing lid 3004 and / or disconnected by opening the housing lid 3004. In some embodiments, the housing 3002 and the main body can be connected to each other by moving the housing 3002 relative to the main body in an attachment direction, wherein the angle between the rotation axis and the attachment direction is between 20° and 160°. In some embodiments, the housing 3002 and the main body can be unlocked from each other by moving the housing 3002 relative to the main body in an unlocking direction, wherein the angle between the rotation axis and the unlocking direction is between 20° and 160°. In some embodiments, the angle between the attachment direction and the unlocking direction may be between -45° and 45°.

[0361] In some embodiments, the humidification assembly 220 and the main body of the respiratory ventilation device 110 can be fluidically connected via at least one connection port for forming at least one flow channel between the main body of the respiratory ventilation device 110 and the liquid chamber 3000. In some embodiments, the at least one connection port (e.g., connector 2301) can include a gas inlet (e.g., second hole 2307) and a gas outlet (e.g., first hole 2306). In some embodiments, the connection port (e.g., connector 2301) can include an axial seal (e.g., first protrusion 2311 and / or second protrusion 2312) for fluid-tightly connecting the gas inlet 3102 and the gas outlet 3104. In some embodiments, the inner surface of the axial seal can at least partially form the flow channel. In some embodiments, the axial seal can define a sealing plane. In some embodiments, the angle between the sealing plane and the liquid level within the liquid chamber 3000 can be between -75° and 75° (e.g., -30° and 30°). In some embodiments, the angle between the sealing plane and the attachment direction may be between 15° and 65°. In some embodiments, the angle between the liquid level and the attachment direction and / or the unlocking direction may be between 45° and 135°.

[0362] In some embodiments, liquid chamber 3000 can be removably coupled to the body of respiratory ventilation device 110 via a push-push mechanism (eg, push-push mechanism 1904 ).

[0363] In some embodiments, the push direction of the push-push mechanism can be substantially perpendicular to the rotational axis of the connection mechanism. In some embodiments, the humidification assembly 220 and the main body of the respiratory ventilation device 110 can be fluidly connected by closing the case lid 3004 in the push direction of the push-push mechanism when the case 3002 is attached to the main body and / or by attaching the liquid chamber 3000 to the main body in the push direction when the case lid 3004 is closed.

[0364] The shape of the case 3002 may include a cube, a rectangular parallelepiped, or an irregular shape that can match the main body of the respiratory ventilation device 110. The case 3002 may be transparent, opaque, or translucent. In some embodiments, the case 3002 may include one or more marks for indicating the liquid level (e.g., water level) of one or more liquids in the case 3002. For example, the case 3002 may include a first adhesive mark located on the side surface of the case 3002 indicating the minimum liquid level allowed and / or a second adhesive mark located on the side surface of the case 3002 indicating the maximum liquid level allowed. As another example, the case 3002 may include a float (e.g., a colored float) floating on the one or more liquids within the case 3002. In some embodiments, the case 3002 may be equipped with a sensor for detecting the liquid level of one or more liquids. More description of the case 3002 can be found elsewhere in this disclosure (e.g., Figure 18A 、 18B and 32A-32C and their descriptions).

[0365] In some embodiments, the shape of the case cover 3004 can be similar to or different from the shape of the case body 3002. The shape of the case cover 3004 can include a cube, a rectangular parallelepiped, or an irregular shape that can fit the main body of the respiratory ventilation device 110. The material of the case cover 3004 can be similar to or different from the material of the case body 3002. The case cover 3004 can be transparent, opaque, or translucent. Further description of the case cover 3004 can be found elsewhere in this disclosure (e.g., Figure 31 and 37A -42B and its description).

[0366] In some embodiments, the lid 3004 may include a handle 3006 and one or more buckles (e.g., a first buckle 3008a and / or a second buckle 3008b) located on the rear side of the handle 3006. The handle 3006 may be configured to facilitate opening and / or closing of the lid 3004. The case 3002 may include one or more recesses (e.g., a first recess 3010a or a second recess 3010b) located opposite the handle 3006 (particularly corresponding to the position of the one or more buckles on the handle). When the lid 3004 is closed, the lid 3004 may be secured to the case 3002 through the engagement of the one or more buckles and the one or more recesses. In some embodiments, the first recess 3010a and / or the second recess 3010b may be equipped with a transverse bar. In some embodiments, the first buckle 3008a and / or the second buckle 3008b can be fastened via the transverse rod such that the case lid 3004 can be fastened to the case body 3002 .

[0367] In some embodiments, the box cover 3004 can be rotatably connected to the box body 3002 via a connection mechanism 3009. In some embodiments, the box cover 3004 can be pivotally connected to the box body 3002 by providing a connection mechanism 3009 having a rotation axis. In some embodiments, the box cover 3004 can be opened by rotating to a specific angle (e.g., 90 degrees, 100 degrees, etc.) relative to the box body 3002. The specific angle can be associated with the maximum rotational movement of the box cover 3004. In some embodiments, the liquid chamber 3000 can be opened from the front surface of the respiratory ventilation device 110. In some embodiments, as Figure 30A and 30B As shown, the connecting mechanism 3009 can be provided on the rear side (or rear surface) of the respiratory ventilation device 110, and the handle 3006 can be provided on the front surface of the respiratory ventilation device 110, so that when the box cover 3004 is opened, the lower surface of the box cover 3004 can be substantially upright and face the front surface of the respiratory ventilation device 110. In some embodiments, the connecting mechanism 3009 can be provided on the side surface of the respiratory ventilation device 110 away from the main body of the respiratory ventilation device 110, the handle 3006 can be provided on the top surface of the respiratory ventilation device 110, and the box cover 3004 can be opened so that the lower surface of the box cover 3004 can be substantially upright and face the main body (not shown) of the respiratory ventilation device 110. In some embodiments, the connecting mechanism 3009 can be configured as a guide groove (not shown), and the box cover 3004 can be opened by moving horizontally relative to the box body 3002. More description of the connecting mechanism 3009 can be found elsewhere in this disclosure (e.g., Figures 33A-36B and its description).

[0368] In some embodiments, the liquid chamber 3000 may include a connector (e.g. Figure 18A and 18B 3004) is configured to provide a sealed connection between the housing 3002 and the lid 3004 so that the liquid chamber 3000 is sealed when the lid 3004 is closed to the housing 3002. The connector can be made of a material having properties such as sealing, flexibility, elasticity, or any combination thereof. For example, the connector can include a flexible rubber (e.g., silicone) or a mixture of flexible rubber and hard rubber. In some embodiments, the connector can be fixed to the bottom surface of the lid 3004 and / or the upper surface of the housing 3002.

[0369] It should be noted that the above description of the liquid chamber 3000 is provided for illustrative purposes only and is not intended to limit the scope of the present disclosure. For those skilled in the art, various changes and modifications can be made under the guidance of the present disclosure. However, these changes and modifications do not depart from the scope of the present disclosure. For example, the case 3002 of the liquid chamber 3000 may be equipped with a sensor for detecting the liquid level of one or more liquids. When the liquid level is less than a predetermined level, the respiratory ventilation device 110 can generate a reminder based on the signal of the sensor. As another example, the case cover 3004 can slide obliquely relative to the case 3002. As another example, the case cover 3004 can slide in an arc at a certain angle relative to the case 3002.

[0370] Figure 31 An exemplary case cover for a liquid chamber of a respiratory ventilation device according to some embodiments of the present disclosure is shown. Case cover 3004 may include a cover shell. The cover shell may include a front surface corresponding to the front surface of respiratory ventilation device 110, a rear surface corresponding to the rear surface of respiratory ventilation device 110, a top surface remote from a corresponding case (e.g., case 3002), a bottom surface that may contact case 3002, a side surface proximal to the body of respiratory ventilation device 110, a side surface remote from the body of respiratory ventilation device 110, and the like. Case cover 3004 may include a gas inlet 3102, a gas outlet 3104, a handle 3006, a connector 3108 of a connection mechanism 3009, and the like. Gas inlet 3102 may be configured to introduce pressurized respiratory gas from the body of respiratory ventilation device 110 into the liquid chamber (e.g., liquid chamber 3000). Gas outlet 3104 may be configured to introduce humidified and pressurized respiratory gas from the liquid chamber back into the body of respiratory ventilation device 110.

[0371] like Figure 31 As shown, the handle 3006 can be provided on the front surface of the box cover 3004. The connector 3108 of the connection mechanism 3009 can be provided on the rear surface of the box cover 3004. The gas inlet 3102 and the gas outlet 3104 can be provided on a side surface (e.g., an inclined surface) of the box cover 3004 that is close to the main body of the respiratory ventilation device 110. In some embodiments, the gas inlet 3102 and the gas outlet 3104 can be provided on a portion of the bottom surface of the box cover 3004 (see FIG. Figure 26B The gas inlet 3102 and the gas outlet 3104 may be located close to the main body of the respiratory ventilation device and may not be in contact with the housing 3002 .

[0372] Figures 32A-32C An exemplary housing of a liquid chamber of a respiratory ventilation device is shown, according to some embodiments of the present disclosure. Figures 32A-32CThe housing 3002 is shown in different views. The housing 3002 may include a front surface facing the user of the respiratory ventilation device 110, a rear surface facing away from the user of the respiratory ventilation device 110, a top surface that may contact the housing cover 3004, a bottom surface facing away from the housing cover 3004, a side surface close to the body of the respiratory ventilation device 110, a side surface facing away from the body of the respiratory ventilation device 110, etc. The housing 3002 may include a connector 3202 of a connection mechanism 3009, a bolt 3204, one or more notches 3010, etc.

[0373] like Figures 32A-32C As shown, the connecting member 3202 of the connecting mechanism 3009 can be disposed on the rear surface of the housing 3002. The connecting member 3202 of the connecting mechanism 3009 and the connecting member 3108 of the connecting mechanism 3009 can form an integral connecting mechanism 3009. The bolt 3204 can be disposed below the bottom surface of the housing 3002. The bolt 3204 can be fixed to the bottom surface of the housing 3002 by the connecting member 3205. In some embodiments, the bolt 3204 can be a push-push mechanism (e.g., Figure 19-21D The one or more recesses 3010 may be provided on the front surface of the case 3002 to coincide with the handle 3006 of the case lid 3004.

[0374] In some embodiments, the side surface of the liquid chamber 3000 proximate the body of the respiratory ventilation device 110 can be angled relative to the horizontal plane. In some embodiments, the angle between the side surface of the case 3002 proximate the body of the respiratory ventilation device 110 and the horizontal plane can be greater than the angle between the inclined surface of the case cover 3004 and the horizontal plane, which can facilitate a sealed connection between the case cover 3004 and the body of the respiratory ventilation device 110. In some embodiments, the front surface of the case 3002, the rear surface of the case 3002, and / or the side surface of the case 3002 distal from the respiratory ventilation device 110 can extend downward to one or more baffles (e.g., baffles 3011a, 3011b, and / or 3011c) located below the bottom surface. If the liquid chamber is mounted on the respiratory ventilation device 110, the baffles 3011a, 3011b, and / or 3011c can form a space to accommodate a portion of the base of the main body of the respiratory ventilation device 110 (e.g., a portion of the base plate 110 and / or the heating device 14). If the liquid chamber is placed separately, the baffles 3011a, 3011b, and / or 3011c can support the box 3002 (or the liquid chamber) and / or protect the bolt 3204 and the connector 3205. In some embodiments, the bolt 3204 and the connector 3205 can also be referred to as a push rod (e.g., Figure 19 Push rod 1906 shown in ).

[0375] Figure 33A and 33B illustrative examples of boxes according to some embodiments of the present disclosure are shown. Figure 33A and 33B As shown, the housing 3300 may include one or more first connectors 3310 . In some embodiments, each of the one or more first connectors 3310 may include a pin hole 3320 , a protruding column 3340 , and / or a first inclined guide surface 3330 .

[0376] Figure 34A and 34B An exemplary case cover according to some embodiments of the present disclosure is shown. Figure 34A and 34B As shown, the case lid 3400 may include one or more second connectors 3410. In some embodiments, each of the one or more second connectors 3410 may include a pin 3420, a second inclined guide surface 3430, a groove 3440, and / or a guide slot 3450. In some embodiments, the pin 3420 may be placed in a pin hole 3320, allowing the case lid 3400 to be secured to the case 3300. The pin 3420 may rotate within the pin hole 3320 during the process of opening and / or closing the case lid 3400. In some embodiments, the first inclined guide surface 3330 of the first connector 3310 and the second inclined guide surface 3430 of the second connector 3410 may be configured to facilitate mounting the case lid 3400 on the case 3300. In some embodiments, the guide slot 3450 may include a first end adjacent to the groove 3440 and a second end distal to the groove 3440. In some embodiments, the depth of the guide slot 3450 may gradually change from a relatively small value at the first end to a relatively large value at the second end. In some embodiments, the guide slot 3450 may be curved to accommodate the rotational movement of the case cover 3400 relative to the case body 3300 .

[0377] Figure 35A and 35B FIG. 4 shows the cooperation of the protruding column of the first connecting member of the box body and the groove of the second connecting member of the box cover according to some embodiments of the present disclosure. Figure 35AAs shown, if the lid 3400 is closed, the protruding post 3340 can be positioned at or near the second end of the guide groove 3450. During the process of opening the lid 3400, the protruding post 3340 can gradually slide along the guide groove 3450 from the second end to the first end. The design of the first end of the guide groove 3450 having a relatively small depth relative to the second end of the guide groove 3450 can make it easier for the protruding post 3340 to fall into the groove 3440. The design of the second end of the guide groove 3450 having a relatively large depth relative to the first end of the guide groove 3450 can facilitate the second end of the guide groove 3450 to accommodate the protruding post 3340 when the lid 3400 is closed. In some embodiments, if the lid 3400 is opened to a certain angle, the protruding post 3340 can fall into the groove 3440 and restrict the lid 3400 from rotating back. Because groove 3440 and guide groove 3450 are disconnected and / or the depth of the first end of guide groove 3450 is less than the depth of groove 3440, protruding post 3340 is not easily separated from groove 3440. When protruding post 3340 falls into groove 3440, the disconnection between groove 3440 and guide groove 3450 and / or the relatively small depth of the first end of guide groove 3450 prevent lid 3400 from rotating back without external force (e.g., force from a user). If force is applied to lid 3400 (e.g., by a user (e.g., subject 180)) to close lid 3400, protruding post 3340 can separate from groove 3440 and gradually slide along guide groove 3450 from the first end to the second end until lid 3400 is closed. In some embodiments, the protruding post 3340 may have a hemispherical shape, a semi-elliptical shape, or other convex structure having a curved surface to reduce friction between the protruding post 3340 and the guide groove 3450 .

[0378] Figure 36A and 36B An exemplary connection between the housing and lid of a liquid chamber 3600 according to some embodiments of the present disclosure is shown. In some embodiments, the lid 3400 can be rotatably connected to the housing 3300 via a connection mechanism (e.g., connection mechanism 3009) including a first connection member 3310 and a second connection member 3410. In some embodiments, the first connection member 3310 can be pivotally connected to the second connection member 3410.

[0379] In some embodiments, as Figure 36A and 36B As shown, a pair of first connectors 3310 can be positioned between a pair of second connectors 3410. In some embodiments, a pair of second connectors 3410 can be positioned between a pair of first connectors 3310. In some embodiments, as Figure 36A and 36BAs shown, the first connector 3310 can be disposed on the rear surface of the case 3300. In some embodiments, the first connector 3310 can be disposed on another surface of the case 3300. For example, the first connector 3310 can be disposed on both side surfaces of the case 3300 and close to the rear surface of the case 3300, and correspondingly, the second connector 3410 can be disposed on both side surfaces of the case cover 3400 and close to the rear surface of the case cover 3400. In another example, the first connector 3310 and the second connector 3410 can be hidden in the case 3300 or the case cover 3400, occupying a portion of the space of the case 3300 or the case cover 3400. As another example, the first connector 3310 and the second connector 3410 can be disposed on a side surface of the liquid chamber 3600 and opposite to the gas inlet and / or gas outlet of the gas channel located above the housing 3300 (i.e., if the user faces the front surface of the respiratory ventilation device 110, the first connector 3310 and the second connector 3410 can be disposed on the right side surface of the liquid chamber 3600).

[0380] In some embodiments, the box body 3300 and / or the box cover 3400 may have an irregular shape. Therefore, the shape or size of the first connector 3310 and / or the second connector 3410 may be irregular. For example, Figure 36A and 36B As shown, in order to match the irregular shape of the case 3300 or the case cover 3400, the lengths of the pair of first connectors 3310 can be different, so that when the case cover 3400 is opened, the lower surface of the case cover 3400 can be substantially upright and face the front surface of the respiratory ventilation device 110. In some embodiments, if the shape of the case 3300 and / or the case cover 3400 is regular, the first connector 3310 and / or the second connector 3410 can be regular and symmetrical.

[0381] like Figure 36B As shown, the second connecting member 3410 may include a baffle 3660 or be connected by a baffle 3660. In some embodiments, if the box cover 3400 is opened to a certain angle, the baffle 3660 may be blocked by a portion of the first connecting member 3310, thereby preventing the box cover 3400 from rotating excessively and limiting the maximum rotational movement of the box cover 3400. In some embodiments, the liquid chamber 3600 may include one or more mounting shafts located between the box cover 3400 and the box body 3300. An example of a mounting shaft may be a pin 3420 (see Figure 34B In some embodiments, the mounting shaft may include a first mounting shaft and a second mounting shaft. In some embodiments, the height of the first mounting shaft is greater than the height of the second mounting shaft. In some embodiments, the first mounting shaft may be arranged to be higher than the second mounting shaft.

[0382] It should be noted that the above description of the connection between the housing 3300 and the lid 3400 is provided for illustrative purposes only and is not intended to limit the scope of the present disclosure. A person of ordinary skill in the art may make various changes and modifications based on the teachings of this disclosure. However, such changes and modifications do not depart from the scope of this disclosure. In some embodiments, the connection between the housing 3300 and the lid 3400 may be achieved in other ways, such as a hinged connection. For example, the housing 3300 and the lid 3400 may each include cylindrical holes on the same horizontal line, and the housing 3300 and the lid 3400 may be connected by a hinge pin extending through the holes. As another example, one end of the housing 3300 may include a hollow post having a "C" shape, and correspondingly, one end of the lid 3400 may include a post that matches the hollow post, so that when the lid 3400 is installed on the housing 3300, the post can be clamped into the C-shaped hollow post to achieve a rotatable connection between the housing 3300 and the lid 3400.

[0383] Figure 37A and 37B An exemplary case cover according to some embodiments of the present disclosure is shown. In some embodiments, as Figure 37A and 37B As shown, the box cover 3700 may include a cover shell 3710, a connecting plate 3720, an inner shell 3730, a gas channel sealing frame 3740, a bottom plate 3750, a fixing frame 3760, and a box cover sealing frame 3770. In some embodiments, the connecting plate 3720 may include a first hole 3721 and a second hole 3722. In some embodiments, the first hole 3721 may be a gas inlet of the box cover 3700 (also referred to as a humidification assembly gas inlet). In some embodiments, the second hole 3722 may be a gas outlet of the box cover 3700 (also referred to as a humidification assembly gas outlet). In some embodiments, the connecting plate 3720 may be arranged at an angle on the outside of the cover shell 3710.

[0384] Figure 38 An exemplary cover shell according to some embodiments of the present disclosure is shown. In some embodiments, as Figure 38As shown, the cover 3710 may include a first hole 3711, a second hole 3712, a connecting frame 3713, a baffle 3714, one or more first clips 3715, and one or more second clips 3716. The first hole 3711 and the first hole 3721 of the connecting plate 3720 may serve as a gas inlet for the box cover 3700. The second hole 3712 and the second hole 3722 of the connecting plate 3720 may serve as a gas outlet for the box cover 3700. The connecting plate 3720 may be connected (e.g., fixed) to the connecting frame 3713. In some embodiments, the connecting plate 3720 may be connected to the connecting frame 3713 by bonding, riveting, mortising, clamping, meshing, or the like, or any combination thereof. The baffle 3714 can be used to separate the gas inlet and the gas outlet of the box cover 3700 between the cover shell 3710 and the connecting plate 3720, so that the breathing gas flowing into the box cover 3700 can be isolated from the breathing gas flowing out of the box cover 3700.

[0385] In some embodiments, a sealing strip (not shown) can be used to improve the airtightness of the connection between the connecting frame 3713 and the connecting plate 3720. For example, all joints between the connecting frame 3713 and the connecting plate 3720 can be equipped with a sealing strip. In some embodiments, a sealing strip (not shown) can be provided at the joint between the baffle 3714 and the connecting plate 3720. In some embodiments, such as Figure 37A As shown, a first groove 37215 and / or a second groove 37225 may be provided between the cover shell 3710 and the connecting plate 3720. The first groove 37215 and / or the second groove 37225 may be used to accommodate a portion of a housing (e.g., Figure 36A and 36B 3300) and prevents the liquid from entering the body of the respiratory ventilation device 110. For example, if the liquid chamber (e.g., Figure 36A and 36B If the liquid chamber 3600 shown in the figure is tilted or skewed, a portion of the liquid loaded in the box body 3300 can flow into the box cover 3700, and the first groove 37215 and / or the second groove 37225 can accommodate the said portion of liquid and prevent the said portion of liquid from entering the main body of the respiratory ventilation device 110.

[0386] In some embodiments, the bottom plate 3750 can be secured to the inner shell 3730 by bonding, riveting, mortising, clamping, meshing, or the like, or any combination thereof. In some embodiments, the bottom plate 3750 and the inner shell 3730 can be configured as a single piece. In some embodiments, a first clasp 3715 can be used to secure the inner shell 3730 and the bottom plate 3750 to the cover 3710. For example, the inner shell 3730 and the bottom plate 3750 can be clamped to the cover 3710 using the first clasp 3715. In some embodiments, the first clasp 3715 can be positioned in the middle of the inner sidewall of the cover 3710 opposite the connecting frame 3713. In some embodiments, a second clasp 3716 can be used to secure the fixing frame 3760 to the cover 3710. In some embodiments, a plurality (eg, 4, 6, 8, etc.) of second hooks 3716 may be provided on the inner sidewall of the cover 3710 to secure the fixing frame 3760 to the cover 3710. For example, Figure 38 As shown, each of the two side walls of the cover shell 3710 adjacent to the connecting frame 3713 may include three second hooks 3716. In some embodiments, the box cover sealing frame 3770 may be fixed to the fixing frame 3760. In some embodiments, the fixing frame 3760 and the box cover sealing frame 3770 may be connected by bonding, clamping, meshing, etc. or any combination thereof. The box cover sealing frame 3770 can be used to improve the box body (e.g. Figure 36A and 36B 3700) and the cover 3700. In some embodiments, the cover sealing frame 3770 may be made of a sealing material, such as silicone, rubber, nylon, or any combination thereof. In some embodiments, some or all components of the cover 3710 (e.g., the first hole 3711, the second hole 3712, the connecting frame 3713, the baffle 3714, the first hook 3715, and / or the second hook 3716) may be configured as a single piece.

[0387] In some embodiments, the cover 3710 may be connected and / or capable of being connected to the housing and / or the housing lid 3700. In some embodiments, the cover 3710 may be pivotally mounted relative to the housing. In some embodiments, the liquid-contacting sidewall of the liquid chamber may be at least partially formed by an outer sidewall of the housing that forms the outer surface of the humidification assembly 220. In some embodiments, the housing may be formed with only one opening for filling the liquid and / or for replacing the pressurized respiratory gas. In some embodiments, the housing lid 3700 may be pivotally connected to the housing via a connection mechanism. In some embodiments, at least a portion of the side of the first gas channel proximate the connection mechanism may be covered by a side edge of the humidification assembly gas inlet of the liquid chamber along the flow direction. In some embodiments, at least a portion of the side of the second gas channel proximate the connection mechanism may be covered by a side edge of the humidification assembly gas outlet of the liquid chamber along the flow direction. In some embodiments, the distance between the connection mechanism and the humidification assembly gas outlet may be smaller than the distance between the connection mechanism and the humidification assembly gas inlet.

[0388] Figure 39A and 39B An exemplary inner shell of a case cover according to some embodiments of the present disclosure is shown. Figure 39A and 39B As shown, the inner shell 3730 may include a gas inlet 3731 and / or a gas outlet 3732. In some embodiments, the gas inlet 3731 may be used to pass a first gas channel (e.g., Figure 39A The gas passage indicated by the arrow in FIG) introduces gas (e.g., pressurized breathing gas) into the liquid chamber. Figure 39AAs shown, the first gas channel (also referred to as the gas inlet channel) may include an outlet 3733. In some embodiments, the outlet 3733 of the first gas channel may be used to connect the first gas channel to the housing. Gas may flow out of the first gas channel through the outlet 3733 and into the liquid chamber. In some embodiments, the inner shell 3730 may include a guide plate 3734. In some embodiments, the guide plate 3734 may be disposed on an edge of the outlet 3733 of the first gas channel. In some embodiments, the guide plate 3734 may be disposed on an upper edge and / or a side edge of the outlet 3733 of the first gas channel (e.g., a side edge closer to the gas inlet 3731 and / or gas outlet 3732 of the inner shell 3730). In some embodiments, the guide plate 3734 may be used to guide the gas downward to the housing below the cover 3700. Thus, the guide plate 3734 may reduce the amount of gas flowing into other spaces (e.g., the space between the cover 3710 and the inner shell 3730). In some embodiments, the gas channel sealing frame 3740 can be connected to the inner shell 3730 to ensure airtightness between the inner shell 3730 and the housing 3710. In some embodiments, the gas channel sealing frame 3740 can be fixed to the inner shell 3730 by bonding, riveting, mortising, clamping, meshing, etc. or any combination thereof.

[0389] In some embodiments, the gas inlet 3731 (also referred to as the humidification assembly gas inlet) and the outlet 3733 of the first gas channel can be disposed on different side surfaces of the inner shell 3730. For example, Figure 39A As shown, the gas inlet 3731 can be provided on the right side portion of the first side surface of the inner shell 3730, and the outlet 3733 of the first gas channel can be provided on the left side portion of the second side surface of the inner shell 3730, wherein the second side surface of the inner shell 3730 can be adjacent to the first side surface of the inner shell 3730 in a clockwise direction. The gas inlet 3731 and the outlet 3733 of the first gas channel can be provided as shown in FIG. Figure 39A The arrangement shown makes it difficult for liquid (e.g., water) in the case to enter the main body of the respiratory ventilation device 110 regardless of how the respiratory ventilation device 110 is placed or moved. In some embodiments, the distance between the outlet 3733 of the first gas channel and the gas inlet of the humidification assembly can be greater than the distance between the outlet 3733 of the first gas channel and the gas outlet of the humidification assembly. In some embodiments, the first side surface of the cover shell 3710 of the liquid chamber can face the first side wall of the housing of the main body of the respiratory ventilation device 110.

[0390] In some embodiments, the gas outlet 3732 (also referred to as the humidification assembly gas outlet) can be used to discharge gas through a second gas channel (e.g., Figure 39BThe gas passage indicated by the arrow in the middle (eg, the gas passage indicated by the arrow in the middle) directs the gas (eg, humidified and pressurized breathing gas) back to the main body of the respiratory ventilation device 110. Figure 39B As shown, the second gas channel (also referred to as the gas outlet channel) may include an inlet 3735. In some embodiments, the inlet 3735 of the second gas channel may be used to connect the second gas channel to the housing. Gas may flow from the liquid chamber into the second gas channel through the inlet 3735. In some embodiments, the first gas channel and / or the second gas channel may have a substantially rectangular cross-section. In some embodiments, the first gas channel and the second gas channel may intersect each other.

[0391] In some embodiments, the gas outlet 3732 (also referred to as the humidification assembly gas outlet) and the inlet 3735 of the second gas channel may be disposed on different side surfaces of the inner shell 3730. For example, Figure 39B As shown, the gas outlet 3732 can be provided on the left portion of the first side surface of the inner shell 3730, and the inlet 3735 of the second gas channel can be provided on the right portion of the third side surface of the inner shell 3730, wherein the third side surface of the inner shell 3730 can be adjacent to the first side surface of the inner shell 3730 in a counterclockwise direction. The gas outlet 3732 and the inlet 3735 of the second gas channel can be as shown. Figure 39B The arrangement shown makes it difficult for liquid (e.g., water) in the housing to enter the main body of the respiratory ventilation device 110, regardless of how the respiratory ventilation device 110 is placed or moved. In some embodiments, the first gas channel and the second gas channel can be arranged to be non-parallel (e.g., intersecting) within the liquid chamber, such that the outlet 3733 of the first gas channel and the inlet 3735 of the second gas channel are in different directions. In some embodiments, the distance between the inlet 3735 of the second gas channel and the gas outlet of the humidification assembly can be greater than the distance between the inlet 3735 of the second gas channel and the gas inlet of the humidification assembly.

[0392] In some embodiments, the gas inlet and / or gas outlet of the case cover 3700 (i.e., the gas inlet and / or gas outlet of the humidification assembly of the liquid chamber) may be located on the first side surface of the cover shell 3710 of the liquid chamber (corresponding to the first side surface of the inner shell 3730). In some embodiments, the outlet 3733 of the first gas channel and the inlet 3735 of the second gas channel may be located on opposite side surfaces of the inner shell 3730. For example, the outlet 3733 of the first gas channel may be located on the second side surface of the inner shell 3730, while the inlet 3735 of the second gas channel may be located on the third side surface of the inner shell 3730. In other words, the outlet 3733 of the first gas channel may face the second side surface of the cover shell 3710 corresponding to the second side surface of the inner shell 3730, while the inlet 3735 of the second gas channel may face the third side surface of the cover shell 3710 corresponding to the third side surface of the inner shell 3730.

[0393] In some embodiments, as Figure 39B As shown, part or all of the bottom plate 3750 can be set below the lower edge of the gas inlet 37311 and / or the lower edge of the gas outlet 37321 of the box cover 3700. Therefore, the bottom plate 3750 can accommodate a portion of the liquid in the box body, and the height difference between the bottom plate 3750 and the lower edge of the gas inlet 37311 and / or the lower edge of the gas outlet 37321 can prevent the liquid in the box body from entering the main body of the respiratory ventilation device 110. In some embodiments, the inner shell 3730 may include one or more third hooks 3736. The third hook 3736 can be used to connect the gas channel sealing frame 3740 to the inner shell 3730. Figure 39B As shown, the inner shell 3730 may include three hooks 3736 , and the three hooks 3736 may be equally spaced apart on the bottom edge of the first side surface of the inner shell 3730 .

[0394] Figure 40 FIG. 2 shows an exemplary bottom plate of the inner shell of the box cover according to some embodiments of the present disclosure. Figure 40 As shown, the bottom plate 3750 may include one or more sealing strips 3752 disposed along the edge of the bottom plate 3750. The sealing strips 3752 may be used to improve the airtightness of the connection between the bottom plate 3750 and the inner shell 3730. In some embodiments, the bottom plate 3750 may include a bottom portion of the second gas channel (e.g., the second inclined plate 3751) and a bottom portion of the first gas channel (e.g., the remaining portion of the bottom plate 3750 excluding the second inclined plate 3751).

[0395] Figure 41A and 41B An exemplary internal structure of an inner shell of a tank cover according to some embodiments of the present disclosure is shown. Figure 41A The air intake passages of the tank cover 3700 are shown. Figure 41A An upward view of the tank lid 3710 is shown without the base plate 3750. Figure 41B The air outlet passage of the tank cover 3700 is shown. Figure 41B 3700 is shown in cross-section. In some embodiments, the air inlet passage (ie, Figure 41A The first gas channel indicated by the arrow shown in FIG37 may include a first portion and a second portion. The first portion of the first gas channel may extend from the gas inlet of the box cover 3700 (e.g., the first hole 3721) to a common plane (e.g., the Figure 41A and 41B 3737). The second portion of the first gas channel can extend from the common plane 3737 to the outlet 3733 of the first gas channel. In some embodiments, the second gas channel may include a first portion and a second portion. The first portion of the second gas channel can extend from the inlet of the second gas channel 3735 to the common plane 3737. The second portion of the second gas channel can extend from the common plane 3737 to the gas outlet of the cover 3700 (e.g., the second hole 3722).

[0396] In some embodiments, the first portion of the first gas channel may be along a first side surface of the cover shell 3710 of the box cover 3700 (eg, Figure 38 The side surface including the connecting frame 3713 shown) has an angle (e.g., substantially perpendicular) that is substantially parallel to the second portion of the second gas channel. In some embodiments, the second portion of the first gas channel and the first portion of the second gas channel may be arranged in different layers. In some embodiments, a first projection of the second portion of the first gas channel on a horizontal plane and a second projection of the first portion of the second gas channel on the horizontal plane may intersect or at least partially overlap. In some embodiments, as Figure 41A and 41B As shown, the second portion of the first gas channel may be disposed below the first portion of the second gas channel. In some embodiments, the first portion of the second gas channel may be disposed below the second portion of the first gas channel. In some embodiments, the area of ​​the first cross-section of the first gas channel located on the common plane may be equal to or less than a portion (e.g., half) of the area of ​​the gas inlet (e.g., first hole 3721) of the box cover 3700. In some embodiments, the area of ​​the second cross-section of the second gas channel located on the common plane may be equal to or less than a portion (e.g., half) of the area of ​​the gas outlet (e.g., second hole 3722) of the box cover 3700.

[0397] In some embodiments, a first inclined plate 3739 (see FIG. 37A ) may be provided between the first cross section and the gas inlet (eg, the first hole 3721 ) of the tank cover 3700 . Figure 39B and 41B ). The first inclined plate 3739 can be used to smooth the flow of pressurized respiratory gas in the first gas channel. In some embodiments, the first inclined plate 3739 (see Figure 39B and 41B ) can be provided as part of the inner shell 3730. In some embodiments, a second inclined plate 3751 can be provided between the second cross section and the gas outlet (e.g., second hole 3722) of the box cover 3700. The second inclined plate 3751 can be used to smooth the flow of the humidified and pressurized respiratory gas in the second gas channel. In some embodiments, the second inclined plate 3751 (see Figure 40 and 41B ) may be provided on the bottom of the box cover 3700. For example, the second inclined plate 3751 may be a part of the bottom plate 3750.

[0398] It should be noted that the above description of the can lid 3700 is provided for illustrative purposes only and is not intended to limit the scope of the present disclosure. A person skilled in the art may make various changes and modifications based on the teachings of the present disclosure. However, such changes and modifications do not depart from the scope of the present disclosure. For example, Figure 42A and 42B As shown, the inner shell 4230 of the box cover 4200 may not include the first inclined plate. As another example, the box cover 4200 may not include the second inclined plate. As another example, the bottom of the box cover 4200 may be horizontally aligned with the lower edge of the gas inlet 4221 and / or the gas outlet 42. In some embodiments, the first inclined plate 3739 (see FIG. Figure 39B and 41B ) can be disposed between the first cross section of the canister cover 3700 and the air inlet (e.g., the first hole 3721). The first inclined plate 3739 can be configured to smooth the flow of pressurized breathing gas in the first gas channel. In some embodiments, the first inclined plate 3739 (see Figure 39B and 41B ) can be provided as part of the inner shell 3730. In some embodiments, a second inclined plate 3751 can be provided between the second cross section of the case cover 3700 and the gas outlet (e.g., the second hole 3722). The second inclined plate 3751 can be configured to smooth the flow of the humidified and pressurized respiratory gas in the second gas channel. In some embodiments, the second inclined plate 3751 (see Figure 40 and 41B ) can be provided on the bottom of the box cover 3700. For example, the second inclined plate 3751 can be a part of the bottom plate 3750. The lower edge of 22 is aligned. Figure 42Aand 42B Another exemplary tank cover according to some embodiments of the present disclosure is shown.

[0399] Figures 43A-43C 1 shows exemplary electronic components in the body of a respiratory ventilation device according to some embodiments of the present disclosure. In some embodiments, as Figure 43A As shown, the electronic components 4300 in the main body may include one or more printed circuit boards (PCBs) 4320, a switch button 4310, a wireless module assembly 4330, a knob 4350, a secure digital (SD) card read-write storage module 4340, a panel 4360, a home button 4370, and a display 4380. In some embodiments, the printed circuit board (PCB) 4320 may include one or more processors (e.g., ARM, PLD, MCU, DSP, FPGA, SoC), one or more controllers, one or more resistors, one or more capacitors, one or more inductors, one or more crystal oscillators, one or more ceramic filters, one or more mechanical switches, one or more connectors, one or more diodes, one or more transistors, one or more thyristors, one or more integrated circuits, one or more sensors (e.g., flow sensor, pressure sensor, humidity sensor, temperature sensor, etc.). In some embodiments, one or more processors (and / or one or more controllers) can be coupled to one or more electronic components 4300, switch button 4310, wireless module assembly 4330, knob 4350, home button 4370, and display 4380 of printed circuit board (PCB) 4320 to control the operation of respiratory ventilation device 110. For example, if a user (e.g., subject 180) presses switch button 4310, the processor can be triggered to control the start or stop of respiratory ventilation device 110. In some embodiments, gas pressurization unit 210 can be coupled (or electrically connected) to electronic component 4300. In some embodiments, electronic component 4300 can include gas pressurization unit 210.

[0400] In some embodiments, first hole 4361 may be provided on panel 4360, and knob 4350 may be connected (or coupled) to printed circuit board (PCB) 4320 through first hole 4361. In some embodiments, if knob 4350 is rotated, a controller may control one or more operations of electronic assembly 4300. In some embodiments, knob 4350 may be used to adjust the brightness of display 4380. For example, if knob 4350 is gradually turned in a certain direction (clockwise or counterclockwise), the brightness of display 4380 may increase, whereas if knob 4350 is turned in the opposite direction, the brightness of display 4380 may decrease. In some other embodiments, knob 4350 may be used to adjust airflow. For example, if knob 4350 is gradually turned in a certain direction (clockwise or counterclockwise), the airflow may increase, whereas if knob 4350 is turned in the opposite direction, the airflow may decrease. In some embodiments, knob 4350 may function as an on / off button. In some implementations, knob 4350 can be used to adjust the pressure of the breathing gas flowing in the gas passageway of respiratory ventilation device 110. For example, if knob 4350 is gradually turned in a certain direction (clockwise or counterclockwise), the pressure of the breathing gas can become greater, whereas, if knob 4350 is turned in the opposite direction, the pressure of the breathing gas can become less.

[0401] In some embodiments, panel 4360 can be used to protect display 4380 from damage and / or enhance the overall appearance of respiratory ventilation device 110. In some embodiments, panel 4360 can be transparent. In some embodiments, information displayed on display 4380 can be viewed through panel 4360. The information displayed on display 4380 can include a user interface, one or more operating parameters generated or detected during operation of respiratory ventilation device 110, vital sign information of a user (e.g., subject 180), and the like. In some embodiments, the operating parameters can include pressure of the respiratory gas, temperature of the respiratory gas, humidity of the respiratory gas, operating mode of respiratory ventilation device 110, status of peripheral devices, operating time, and the like. In some embodiments, the vital sign information can include the user's respiratory rate, snoring, sleep status, tidal volume, and the like. In some other embodiments, a light sensor for detecting the intensity of ambient light can be disposed on the exterior of respiratory ventilation device 110 and coupled to electronic component 4300, so that the processor (and / or controller) can automatically control the brightness of display 4380 based on the intensity of the ambient light. In some embodiments, the display 4380 may include a liquid crystal display (LCD) screen, a light emitting diode (LED) screen, or the like.

[0402] In some embodiments, the home button 4370 can be used to reset the operating parameters to their original or initial values. In some embodiments, the home button 4370 can be used to control the interface to return to the home page or the previous page. In some embodiments, a second hole 4362 can be provided on the panel 4360, and the home button 4370 can be connected to (or coupled to) the printed circuit board (PCB) 4320 through the second hole 4362.

[0403] In some embodiments, wireless module assembly 4330 can be used to control respiratory ventilation device 110. In some embodiments, wireless module assembly 4330 can include a Bluetooth module, a ZigBee module, a mobile communication module, a radio frequency (RF) communication module, a WiFi module, or the like, or a combination thereof. In some embodiments, respiratory ventilation device 110 can connect to the internet via the WiFi module. In some embodiments, operating parameters of respiratory ventilation device 110 can be adjusted (or controlled, or changed) by a remote computer (e.g., a mobile terminal). In some embodiments, the radio frequency (RF) communication module can be coupled to a remote control, and a user (e.g., subject 180) can remotely start, stop, adjust, and / or control the operation of respiratory ventilation device 110 via the remote control. In some embodiments, wireless module assembly 4330 can be coupled to one or more sensors provided in respiratory ventilation device 110 to obtain information detected by the sensors. For example, wireless module assembly 4330 can be coupled to a flow sensor positioned in a gas passage of respiratory ventilation device 110 to obtain the flow rate of respiratory gas.

[0404] In some embodiments, a secure digital (SD) card read-write storage module 4340 can be used to accommodate a secure digital (SD) card, read information from the SD card, and / or write information to the SD card. It should be noted that a secure digital (SD) card may not be necessary. In some embodiments, the secure digital (SD) card can be used to store a user's vital sign information, operating parameters generated or detected during operation of the respiratory ventilation device 110, and / or one or more preset operating parameters. In some embodiments, the storage size of the secure digital (SD) card can be selected by the user.

[0405] Figure 44A and 44B An exemplary heating device according to some embodiments of the present disclosure is shown. Figure 44A As shown, heating device 4414 can be disposed on substrate 4410 of the main body of respiratory ventilation device 110. In some embodiments, at least a portion of substrate 4410 can be disposed below a liquid chamber (e.g., liquid chamber 320). Heating device 4414 can be used to heat the liquid in the liquid chamber and / or accelerate the evaporation of the liquid in the liquid chamber. In some embodiments, as Figure 44B As shown, the heating device 4414 may include a bracket 4440, a heating plate 4420 and a fixing frame 4430. The fixing frame 4430 can be used to fix the heating plate 4420 to the bracket 4440. In some embodiments, the heating plate 4420 can be fixed to the bracket 4440 by one or more screws (or snaps) or any other fixing mechanism. The heating plate 4420 may include, for example, a stainless steel electric heating plate (mica electric heating plate), a ceramic electric heating plate, a cast aluminum electric heating plate, a cast copper electric heating plate, etc. or a combination thereof. In some embodiments, one or more springs 4460 can be provided under the bracket 4440 so that if pressure is applied to or removed from the heating plate 4420, the heating device 4414 can move up and down. More description of the connection between the heating device 4414 and the substrate 4410 can be found elsewhere in this disclosure (e.g. Figures 22A-22D and its description).

[0406] Figure 45 An exemplary liquid chamber according to some embodiments of the present disclosure is shown. In some embodiments, the liquid chamber 4500 may include a housing 4530. The housing 4530 can be used to accommodate one or more liquids. In some embodiments, the housing 4530 may include a heat conducting plate 4510. The heat conducting plate 4510 can be used to conduct the heat generated by the heating plate 4420 to the liquid in the housing 4530, so that the liquid can evaporate to produce steam to humidify the respiratory gas. In some embodiments, the heat conducting plate 4510 can be made of a heat conducting material, which includes, for example, one or more metals with heat conductivity (e.g., copper, aluminum), heat conducting silicone, etc., or a combination thereof. In some embodiments, one or more heat conducting coatings (e.g., heat conducting silicone) can be provided on the surface of the heat conducting plate 4510 to promote thermal contact between the heating plate 4420 and the heat conducting plate 4510.

[0407] In some embodiments, the heat conducting plate 4510 can be fixed to the bottom of the housing 4530 by screws or glue. In some embodiments, the bottom of the housing 4530 can include a groove 4520. In some embodiments, the shape of the groove 4520 can match the shape of the heating plate 4420, so that if the housing 4530 is installed on the bottom plate 4410, the heating device 4414 can be completely or partially captured in the groove 4520. As a result, the heating plate 4420 and the heat conducting plate 4510 can be tightly connected.

[0408] In order to reduce heat loss, it may be necessary to ensure that the heating plate 4420 and the heat conducting plate 4510 are in close contact with each other. Figure 44BAs shown in FIG, one or more springs 4460 may be disposed below heating plate 4420. If housing 4530 is mounted above heating device 4414, springs 4460 may be compressed. The compressed springs 4460 may push heating plate 4420 toward heat transfer plate 4510, increasing the contact pressure between heating plate 4420 and heat transfer plate 4510 and ensuring close contact therebetween. In some embodiments, multiple elastic columns may be used in place of springs 4460.

[0409] In some other embodiments, one or more heating rods, one or more electrodes, or one or more ultrasonic atomizers can be installed directly in the tank 4530 to heat the liquid in the tank 4530. In some embodiments, the heating device 4414 can be coupled to (or electrically connected to) the electronic assembly 4300. The controller can control the start, stop, pause, and resume of heating by the heating device 4414, the heating rate of the heating device 4414, the heating power of the heating device 4414, etc., to control the humidity of the respiratory gas.

[0410] Having thus described the basic concepts, it will be apparent to those skilled in the art, after reading this detailed disclosure, that the foregoing detailed disclosure is intended to be presented by way of example only and is not restrictive. Although not expressly stated herein, various changes, improvements, and modifications may be intended by those skilled in the art. Such changes, improvements, and modifications are intended to be suggested by this disclosure and are within the spirit and scope of the exemplary embodiments of the present disclosure.

[0411] In addition, certain terms have been used to describe embodiments of the present disclosure. For example, the terms "one embodiment," "an embodiment," and / or "some embodiments" mean that a particular feature, structure, or characteristic described in conjunction with the embodiment is included in at least one embodiment of the present disclosure. Therefore, it should be emphasized and understood that two or more references to "an embodiment," "one embodiment," or "an alternative embodiment" in various parts of this specification do not necessarily refer to the same embodiment. In addition, particular features, structures, or characteristics may be appropriately combined in one or more embodiments of the present disclosure.

[0412] Furthermore, it will be understood by those skilled in the art that aspects of the present disclosure may be shown and described in any of a number of patentable categories or contexts, including any new and useful method, machine, manufacture, or composition of matter, or any new and useful improvement thereof. Thus, aspects of the present disclosure may be implemented entirely by hardware, entirely by software (including firmware, resident software, microcode, etc.), or a combination of software and hardware implementations, all of which are generally referred to herein as "units," "modules," or "systems." Furthermore, aspects of the present disclosure may take the form of a computer program product embodied in one or more computer-readable media having a computer-readable program code embodied thereon.

[0413] Similarly, it should be understood that in the foregoing descriptions of the embodiments of the present disclosure, various features are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of simplifying the disclosure to aid understanding of one or more of the various inventive embodiments of the present disclosure. However, this method of disclosure should not be interpreted as reflecting an intention that the claimed subject matter requires more features than expressly recited in each claim. Rather, an inventive embodiment may have fewer than all the features of a single foregoing disclosed embodiment.

[0414] In some embodiments, the numbers expressing quantities or properties used to describe and claim certain embodiments of the present application should ...

Claims

1. A humidification assembly configured to humidify pressurized breathing gas from a respiratory ventilation device, the humidification assembly comprising: a liquid chamber configured to contain one or more liquids, the liquid chamber comprising a box body and a box cover; in: The box cover includes a shell, a humidifying component gas inlet, a humidifying component gas outlet, a first gas channel with an outlet, and a second gas channel with an inlet. The humidification assembly gas inlet is configured to introduce pressurized respiratory gas into the housing through the first gas passage, The humidification assembly gas outlet is configured to direct the humidified pressurized breathing gas back into the body of the respiratory ventilation device through the second gas passageway. The humidifying assembly gas inlet and the humidifying assembly gas outlet are provided on the same side surface of the housing, and The first gas channel and the second gas channel are configured as a single piece that is associated with the housing to fluidly connect the first gas channel to the humidification assembly gas inlet and to fluidly connect the second gas channel to the humidification assembly gas outlet.

2. The humidifying assembly according to claim 1, wherein The outer shell includes an inner shell and a cover shell of a layered structure, and the first gas channel and the second gas channel are formed together with the inner shell.

3. The humidifying assembly according to claim 2, wherein: The tank cover includes a bottom plate, and the bottom plate is connected to the inner shell so that the bottom plate forms at least a portion of a surface of at least one of the first gas channel or the second gas channel.

4. The humidifying assembly according to claim 3, wherein: The bottom plate and the inner shell are configured as an integral piece.

5. The humidifying assembly according to claim 1, wherein: The housing is connected and / or connectable to the housing and is pivotally arranged relative to the housing. The humidifying assembly according to claim 1 , wherein: An outlet of the first gas channel for connecting the first gas channel and the box body, and / or an inlet of the second gas channel for connecting the second gas channel and the box body are arranged inside the housing.

7. The humidifying assembly according to claim 6, wherein: The outlet of the first gas passage and the inlet of the second gas passage face opposite inner side surfaces of the housing.

8. The humidifying assembly according to claim 1, wherein: The tank cover further includes at least one guide plate disposed on at least one edge of the outlet of the first gas channel, one of the at least one guide plate being configured to guide the pressurized breathing gas downwardly to the tank body.

9. The humidifying assembly according to claim 8, wherein: The one of the at least one guide plate has an inclination angle relative to a horizontal plane.

10. The humidifying assembly according to claim 8, wherein: The outlet of the first gas channel, the inlet of the second gas channel, and the at least one guide plate are configured so that an angle between a first flow direction of the pressurized breathing gas flowing out of the outlet of the first gas channel and a second flow direction of the pressurized breathing gas flowing into the inlet of the second gas channel is equal to or less than 90 degrees.

11. The humidifying assembly according to claim 1, wherein: A bottom edge of the outlet of the first gas channel is lower than a bottom edge of the inlet of the second gas channel.

12. The humidifying assembly according to claim 1, wherein The first gas channel includes a first portion and a second portion, wherein the first portion and the second portion satisfy at least one of the following conditions: The first portion of the first gas channel is parallel to at least a portion of the second gas channel; An extension direction of the second portion of the first gas channel is different from an extension direction of the first portion of the first gas channel; A bottom surface of the first portion of the first gas channel is lower than a bottom surface of the second portion of the first gas channel.

13. The humidifying assembly according to claim 1, wherein: The cross-sectional areas of at least two locations of the first gas channel are different.

14. The humidifying assembly according to claim 1, wherein A distance between the outlet of the first gas channel and the gas inlet of the humidifying component is greater than a distance between the outlet of the first gas channel and the gas outlet of the humidifying component.

15. The humidifying assembly according to claim 1, wherein At least a portion of the bottom of the first gas channel is located below the lower edge of the gas inlet of the humidifying assembly of the liquid chamber, and / or at least a portion of the bottom of the second gas channel is located below the lower edge of the gas outlet of the humidifying assembly of the liquid chamber.

16. The humidifying assembly according to claim 1, wherein At least a portion of one side of the first gas channel is covered by a side edge of the gas inlet of the humidifying assembly, and / or At least a portion of one side of the second gas channel is covered by a side edge of the gas outlet of the humidifying assembly.

17. A respiratory ventilation device for delivering respiratory gas to a patient interface, the respiratory ventilation device comprising a humidification assembly configured to humidify the respiratory gas, the humidification assembly comprising: a liquid chamber, the liquid chamber being configured to contain one or more liquids, the liquid chamber comprising a box body and a box cover; in: The box cover includes a shell, a humidifying component gas inlet, a humidifying component gas outlet, a first gas channel with an outlet, and a second gas channel with an inlet. The humidification assembly gas inlet is configured to introduce pressurized respiratory gas into the box through the first gas channel, The humidification assembly gas outlet is configured to direct the humidified pressurized respiratory gas back into the main body of the respiratory ventilation device through the second gas passage. The humidifying assembly gas inlet and the humidifying assembly gas outlet are provided on the same side surface of the housing, and The first gas channel and the second gas channel are configured as an integral piece connected to the housing so that the first gas channel is in fluid communication with the humidification assembly gas inlet and the second gas channel is in fluid communication with the humidification assembly gas outlet.

18. The respiratory ventilation apparatus of claim 17, wherein: The humidification assembly is removably connected to the main body of the respiratory ventilation device.

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