Automatic sequencing pretreatment equipment compatible with multiple types of samples to be detected

By designing an automated pre-sequencing equipment compatible with multiple types of samples to be tested, the problem of poor compatibility of existing equipment is solved, automated processing is realized, and processing efficiency and sample quality are improved.

CN120536232AInactive Publication Date: 2025-08-26SHANGHAI JINFUKANG PHARMACEUTICAL ENGINEERING TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202511037737.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-07-28
Publication Date
2025-08-26
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

Existing pre-sequencing equipment is difficult to compatible with multiple types of samples to be tested, resulting in poor equipment compatibility, high operational complexity, large human error and limited overall efficiency.

Method used

Design an automated sequencing pre-processing equipment compatible with multiple types of samples to be tested, including sample receiving devices, nucleic acid extraction devices, nucleic acid mixing devices and library construction devices. By isolating the liquid and solid biological sample entrances and processing areas, automatic transfer and mixing can be achieved, avoid cross-contamination, and improve processing efficiency and quality.

Benefits of technology

Compatible processing of multiple types of samples to be tested is realized, which avoids cross-contamination, improves processing efficiency and sample quality, and reduces operational complexity and artificial errors.

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Abstract

The invention provides automatic sequencing pretreatment equipment compatible with multiple types of to-be-detected samples, and relates to the technical field of nucleic acid sequencing. The apparatus comprises: a sample receiving device comprising a liquid biological sample inlet and a solid biological sample inlet; the nucleic acid extraction device comprises a first transfer module for transferring a to-be-detected sample stored in a liquid biological sample inlet to a liquid biological sample treatment area, and a second transfer module for transferring a to-be-detected sample stored in a solid biological sample inlet to a solid biological sample treatment area, a liquid biological sample treatment area and a solid biological sample treatment area; the liquid biological sample treatment area and the solid biological sample treatment area are used for performing nucleic acid extraction treatment on a to-be-detected sample to obtain a nucleic acid extract; the nucleic acid mixing device is used for mixing nucleic acid extracts; and the library construction device is used for performing library preparation treatment on the nucleic acid extract to obtain a sequencing library. According to the equipment, compatibility processing of multiple types of to-be-tested samples is realized.
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