Traditional Chinese medicine composition for treating bone diseases and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating bone diseases and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared by taking black monkshood, raw semen strychni, datura stramonium, dragon's blood and sappan wood as monarch drugs and taking ground beeltle, centipede, scorpio, Jin snake, zaocys dhumnade, black ant, teasel, rhizoma cibotii, native copper, rhizoma drynariae, radix achyranthis bidentatae, radix salviae miltiorrhizae, raw radix aconiti and the like as ministerial drugs; according to etiology and pathogenesis of bone diseases including cervical spondylosis, scapulohumeral periarthritis, rheumatic arthritis, hyperosteogeny and the like, medicines are reasonably combined, according to the etiology and pathogenesis, warm dredging and attacking evil are taken as main medicines, worm medicines are used for searching collaterals and eliminating evil are taken as essential medicines, the liver and kidney are tonified, the muscles and bones are strengthened, and the evil is prevented from hurting the body resistance; the traditional Chinese medicine can achieve the effects of warming channels and expelling cold, dispelling wind and eliminating dampness, activating meridians to stop pain, searching collaterals and eliminating evil, tonifying the liver and the kidney and the like, can effectively treat various orthopedic diseases, can treat symptoms by attacking evil and dredging collaterals, can treat root causes by tonifying the liver and the kidney, and achieves the purpose of treating both symptoms and root causes.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a traditional Chinese medicine composition for treating bone diseases and application thereof. Background Art

[0002] Orthopedic diseases, such as cervical spondylosis, frozen shoulder, rheumatoid arthritis, and bone hyperplasia, have long garnered significant attention in the medical community. In today's society, a wide range of treatment options are available for these orthopedic conditions, including surgical removal of the lesion, injections, Western medication, massage, and moxibustion. However, surgery and Western medications have significant side effects and are relatively expensive, making them inconvenient for patients to take long-term and often treating symptoms rather than the root cause. Massage and moxibustion cannot directly reach the lesion, providing only temporary relief but not a cure. Consequently, these conditions cause significant physical and psychological distress to patients, necessitating the development of therapeutics for these joint and bone diseases. While traditional Chinese medicine (TCM) treatments for conditions such as cervical spondylosis, frozen shoulder, rheumatoid arthritis, bone hyperplasia, bone spurs, lumbar disc herniation, and lumbar muscle strain, which are categorized as "arthritis," "bone arthritis," and "low back pain," are currently available, most medications offer limited efficacy. However, orthopedic conditions often present with multiple symptoms simultaneously, which can easily lead to suboptimal treatment outcomes. Summary of the Invention

[0003] Therefore, based on the above background, the present invention provides a Chinese medicine composition for treating bone diseases and its application. Rational combination of drugs can effectively treat a variety of orthopedic diseases including cervical spondylosis, periarthritis of the shoulder, rheumatoid arthritis, bone hyperplasia, etc.

[0004] The technical solution provided by the present invention is:

[0005] A traditional Chinese medicine composition for treating bone diseases, comprising the following raw materials by weight:

[0006] 30-80 parts of processed Arisaema, 30-90 parts of processed Pinellia, 30-90 parts of raw Chuanwu, 30-50 parts of raw Kusnezoffii, 30-100 parts of natural copper, 30-100 parts of processed frankincense, 30-100 parts of myrrh, 30-100 parts of safflower, 12-90 parts of Chuanxiong, 30-90 parts of Chinese angelica, 30-90 parts of Zedoaria, 30-90 parts of Sanguisorba officinalis, and 30-90 parts of catechu , 30-100 parts of peach kernel, 30-90 parts of papaya, 30-90 parts of clematis, 15-100 parts of pepper, 30-90 parts of borneol, 20-50 parts of camphor, 30-90 parts of cinnamon bark, 30-90 parts of strychnine seeds, 30-90 parts of ground beetle, 30-90 parts of geranium, 30-90 parts of millennium jian, 30-100 parts of chuanxiong, 30-100 parts of liujiu 30-90 parts of rhizoma drynariae, 30-90 parts of realgar, 30-100 parts of cyathula, 30-90 parts of seven-leaf parsnip, 30-90 parts of datura, 30-90 parts of angelica dahurica, 30-90 parts of herba scutellariae, 30-90 parts of whole worm, 30-90 parts of snake, 30-90 parts of snake, 30-90 parts of pittosporum tobira, 30-90 parts of black aconite root, 30-90 parts of scutellariae, 30-90 parts of whole worm, 30-90 parts of snake ... pittosporum tobira bark, 30-90 parts of black aconite root. 0 parts, 30-90 parts of Herba Lycopodii, 30-90 parts of Radix Asari, 30-90 parts of Rhizoma Et Rhizoma, 30-100 parts of Radix Angelicae Dahuricae, 30-100 parts of Radix Saposhnikoviae, 30-100 parts of Cibotium bark, 30-50 parts of Rhubarb, 30-50 parts of Sappan Wood, 30-90 parts of Salvia miltiorrhizae, 30-90 parts of Black Ant, 30-90 parts of Herba Ephedrae, 30-90 parts of Radix Et Rhizoma, and 30-90 parts of Ephedrae.

[0007] Furthermore, it is composed of the following raw materials by weight:

[0008] 45 parts of processed Arisaema, 45 parts of processed Pinellia, 30 parts of raw Chuanwu, 30 parts of raw Kusnezoffii, 45 parts of natural copper, 40 parts of processed frankincense, 35 parts of myrrh, 50 parts of safflower, 35 parts of Chuanxiong, 40 parts of angelica, 30 parts of Zedoaria, 40 parts of Sanguisorba officinalis, 35 parts of catechu, 45 parts of peach kernel, 35 parts of papaya, 45 parts of clematis, 25 parts of Zanthoxylum bungeanum, 30 parts of borneol, 25 parts of camphor, 30 parts of cinnamon bark, 45 parts of raw Strychnos nux vomica, 35 parts of Eupolyphaga sinensis, 40 parts of Geranium, 35 parts of Millennium scutellaria, 35 parts of Dipsacus asper, and 30 parts of Achyranthes bidentata , 45 parts of Drynaria fortunei, 40 parts of realgar, 45 parts of Cyathula, 45 parts of Seven-leaf Parsley, 40 parts of Datura, 40 parts of Angelica dahurica, 45 parts of Herba striatae, 45 parts of Herba scutellariae, 35 parts of Scolopendra, 30 parts of Whole Insects, 35 parts of Snake, 35 parts of Snake, 40 parts of Cortex Pittosporume, 50 parts of Aconite, 40 parts of Herba Lycopodii, 45 parts of Caulis Aconiti Lateralis Preparata, 35 parts of Asarum, 45 parts of Notopterygium, 45 parts of Angelica dahurica, 40 parts of Saposhnikovia divaricata, 35 parts of Cibotium barometz, 30 parts of Rhubarb, 30 parts of Sappan Wood, 35 parts of Salvia miltiorrhiza, 35 parts of Black Ant, 40 parts of Herba Ephedrae, and 40 parts of Ephedra sinica.

[0009] Furthermore, it is composed of the following raw materials by weight:

[0010] 30 parts of processed Arisaema, 35 parts of processed Pinellia, 45 parts of raw Chuanwu, 45 parts of raw Kusnezoffii, 50 parts of natural copper, 35 parts of processed frankincense, 35 parts of myrrh, 45 parts of safflower, 40 parts of Chuanxiong, 45 parts of Chinese angelica, 40 parts of Zedoaria, 35 parts of Sanguisorba officinalis, 35 parts of catechu, 55 parts of peach kernel, 45 parts of papaya, 45 parts of clematis, 25 parts of Zanthoxylum bungeanum, 30 parts of borneol, 25 parts of camphor, 30 parts of cinnamon bark, 35 parts of raw Strychnos nux vomica, 35 parts of Eupolyphaga sinensis, 45 parts of Geranium, 40 parts of Millennium scutellaria, 35 parts of Dipsacus asper, and 45 parts of Achyranthes bidentata , 50 parts of Drynaria Rhizoma, 40 parts of Realgar, 45 parts of Cyathula, 40 parts of Seven-leaf Parsley, 45 parts of Datura, 40 parts of Angelicae Pubescentis, 45 parts of Herba Scutellariae, 40 parts of Scolopendra, 35 parts of Whole Insects, 30 parts of Snake, 35 parts of Snake, 30 parts of Pittosporum tobira, 40 parts of Black Aconite, 40 parts of Herba Lycopodii, 40 parts of Caulis Aconiti Lateralis Preparata, 40 parts of Asarum, 40 parts of Notopterygium, 30 parts of Angelicae Dahuricae, 40 parts of Saposhnikovia divaricata, 45 parts of Cibotium barometz, 35 parts of Rhubarb, 30 parts of Sappan Wood, 45 parts of Salvia miltiorrhiza, 45 parts of Black Ant, 40 parts of Herba Ephedrae, and 35 parts of Ephedra.

[0011] Based on the same inventive concept, the present invention also provides the use of the above-mentioned traditional Chinese medicine composition for treating bone diseases in the preparation of external medicines for treating bone diseases.

[0012] Furthermore, the bone diseases include cervical spondylosis, periarthritis of the shoulder, rheumatoid arthritis, bone hyperplasia, bone spurs, lumbar disc herniation, and lumbar muscle strain.

[0013] Based on the same inventive concept, the present invention also provides a medicinal wine for treating bone diseases, which is prepared from the above-mentioned traditional Chinese medicine composition for treating bone diseases.

[0014] Furthermore, its preparation comprises the following steps:

[0015] S1: Take each raw material according to the amount and crush them separately;

[0016] S2: adding the raw materials crushed in step S1 into white wine and soaking them for not less than 40 days, filtering and taking the filtrate to obtain the medicinal wine.

[0017] Furthermore, the alcohol content of the liquor in step S2 is above 45 degrees.

[0018] Traditional Chinese medicine believes that the core cause and pathogenesis of bone diseases including cervical spondylosis, periarthritis of the shoulder, rheumatoid arthritis, and bone hyperplasia are mostly due to exogenous wind, cold, and dampness. "Suwen·Bi Lun" says: "Wind, cold, and dampness, the three qi, mixed together, form bi." It is often accompanied by liver and kidney deficiency, which causes the liver to fail to nourish the tendons, the kidneys to fail to control the bones, and blood stasis. Long-term bi causes phlegm and blood stasis to remain in the meridians. Therefore, the pathogenesis of the above symptoms is mostly due to the combination of wind, cold, dampness, blood stasis and phlegm, and liver and kidney deficiency.

[0019] Therefore, aiming at the etiology and pathogenesis of the above-mentioned bone diseases, the present invention rationally combines and groups drugs, wherein black aconite root, raw Strychnos nux vomica, Datura stramonium, Sanguisorba officinalis, and Sappan wood are used as the main drugs, which can warm the meridians and dispel cold, dredge the collaterals and relieve pain, and break up blood stasis and eliminate symptoms. Among them, black aconite root is very pungent and hot, and can strongly warm the meridians and dispel cold, dispel wind and dampness, and relieve pain, and break up deep-seated cold. Raw Strychnos nux vomica and Datura dredge the collaterals and relieve pain, and paralyze the nerves. Sanguisorba officinalis and Sappan wood can break up blood and remove blood stasis, dredge the collaterals and relieve pain.

[0020] The medicine uses the Chinese earthworm, centipede, scorpion, Jin snake, black-striped snake, black ant, Chuanxiong, dog spine, natural copper, bone drynail, Achyranthes bidentata, Salvia miltiorrhiza, raw Chuanwu, raw Caowu, Liuji Nu, safflower, peach kernel, Chuanxiong, Salvia miltiorrhiza, processed Arisaema, processed Pinellia ternata, and Ze Lan as the ministerial medicines to search the meridians and eliminate evil, and nourish the liver and kidneys. Among them, the Chinese earthworm, centipede, scorpion, Jin snake, and black-striped snake are used to search the wind and dredge the meridians, attack toxins and disperse nodules; black ant nourishes the kidneys and strengthens the tendons and bones, and eliminates rheumatism; Chuanxiong, dog spine, bone drynail, and Achyranthes bidentata nourish the liver and kidneys, strengthen the tendons and bones; natural copper connects tendons and bones; raw Chuanwu and raw Caowu help black aconite warm the meridians and dispel cold, dispel wind and dampness; Liuji Nu, safflower, peach kernel, Chuanxiong, and Salvia miltiorrhiza break up blood and remove blood stasis, dredge the meridians and relieve pain; processed Arisaema ternata, processed Pinellia ternata, and Ze Lan remove dampness and resolve phlegm, disperse nodules and reduce swelling to help the monarch medicine clear phlegm and blood stasis blocked meridians.

[0021] The adjuvants are prepared frankincense, myrrh, clematis root, herba scutellariae, geranium, scutellariae scutellariae, herba scutellariae, angelica root, angelica root, angelica root, angelica root, angelica root, angelica root, angelica root, angelica root, angelica root, angelica root, angelica root, realgar, angelica root, catechu, angelica root, realgar ...

[0022] Cinnamon bark, asarum, angelica dahurica, borneol, camphor, Sichuan pepper and ephedra are used as guiding drugs. Cassia twig and cinnamon warm and unblock the meridians, leading the medicine into the blood. Asarum and angelica dahurica dispel cold and open the orifices, leading the medicine upward. Achyranthes bidentata also serves as a guiding drug, leading the medicine downward to nourish the liver and kidneys. Borneol and camphor have aromatic properties, promoting transdermal absorption of the medicine and enhancing pain relief. Sichuan pepper and ephedra warm and unblock the pores, helping the medicine penetrate.

[0023] Looking at the whole prescription, the present invention mainly takes warming and promoting circulation to attack evil, and the main purpose is to use insect medicine to search for evil and eliminate evil, and nourish the liver and kidney to strengthen the tendons and bones, and prevent evil from damaging the body. The various medicines are reasonably matched, which can achieve the effects of warming the meridians and dispersing cold, dispelling wind and dampness, promoting circulation to relieve pain, searching for evil and eliminating evil, and nourishing the liver and kidney. It can effectively treat a variety of orthopedic diseases, and the present invention can treat the symptoms by attacking evil and unblocking the meridians, and treat the root cause by nourishing the liver and kidney, thereby achieving both symptomatic and root treatment. DETAILED DESCRIPTION

[0024] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0025] Example 1: A Chinese medicine composition for treating bone disease, which is composed of the following raw materials by weight:

[0026] 45 parts of processed Arisaema, 45 parts of processed Pinellia, 30 parts of raw Chuanwu, 30 parts of raw Kusnezoffii, 45 parts of natural copper, 40 parts of processed frankincense, 35 parts of myrrh, 50 parts of safflower, 35 parts of Chuanxiong, 40 parts of angelica, 30 parts of Zedoaria, 40 parts of Sanguisorba officinalis, 35 parts of catechu, 45 parts of peach kernel, 35 parts of papaya, 45 parts of clematis, 25 parts of Zanthoxylum bungeanum, 30 parts of borneol, 25 parts of camphor, 30 parts of cinnamon bark, 45 parts of raw Strychnos nux vomica, 35 parts of Eupolyphaga sinensis, 40 parts of Geranium, 35 parts of Millennium scutellaria, 35 parts of Dipsacus asper, and 30 parts of Achyranthes bidentata , 45 parts of Drynaria fortunei, 40 parts of realgar, 45 parts of Cyathula, 45 parts of Seven-leaf Parsley, 40 parts of Datura, 40 parts of Angelica dahurica, 45 parts of Herba striatae, 45 parts of Herba scutellariae, 35 parts of Scolopendra, 30 parts of Whole Insects, 35 parts of Snake, 35 parts of Snake, 40 parts of Cortex Pittosporume, 50 parts of Aconite, 40 parts of Herba Lycopodii, 45 parts of Caulis Aconiti Lateralis Preparata, 35 parts of Asarum, 45 parts of Notopterygium, 45 parts of Angelica dahurica, 40 parts of Saposhnikovia divaricata, 35 parts of Cibotium barometz, 30 parts of Rhubarb, 30 parts of Sappan Wood, 35 parts of Salvia miltiorrhiza, 35 parts of Black Ant, 40 parts of Herba Ephedrae, and 40 parts of Ephedra sinica.

[0027] Example 2: A Chinese medicine composition for treating bone disease, comprising the following raw materials by weight:

[0028] 30 parts of processed Arisaema, 35 parts of processed Pinellia, 45 parts of raw Chuanwu, 45 parts of raw Kusnezoffii, 50 parts of natural copper, 35 parts of processed frankincense, 35 parts of myrrh, 45 parts of safflower, 40 parts of Chuanxiong, 45 parts of Chinese angelica, 40 parts of Zedoaria, 35 parts of Sanguisorba officinalis, 35 parts of catechu, 55 parts of peach kernel, 45 parts of papaya, 45 parts of clematis, 25 parts of Zanthoxylum bungeanum, 30 parts of borneol, 25 parts of camphor, 30 parts of cinnamon bark, 35 parts of raw Strychnos nux vomica, 35 parts of Eupolyphaga sinensis, 45 parts of Geranium, 40 parts of Millennium scutellaria, 35 parts of Dipsacus asper, and 45 parts of Achyranthes bidentata , 50 parts of Drynaria Rhizoma, 40 parts of Realgar, 45 parts of Cyathula, 40 parts of Seven-leaf Parsley, 45 parts of Datura, 40 parts of Angelicae Pubescentis, 45 parts of Herba Scutellariae, 40 parts of Scolopendra, 35 parts of Whole Insects, 30 parts of Snake, 35 parts of Snake, 30 parts of Pittosporum tobira, 40 parts of Black Aconite, 40 parts of Herba Lycopodii, 40 parts of Caulis Aconiti Lateralis Preparata, 40 parts of Asarum, 40 parts of Notopterygium, 30 parts of Angelicae Dahuricae, 40 parts of Saposhnikovia divaricata, 45 parts of Cibotium barometz, 35 parts of Rhubarb, 30 parts of Sappan Wood, 45 parts of Salvia miltiorrhiza, 45 parts of Black Ant, 40 parts of Herba Ephedrae, and 35 parts of Ephedra.

[0029] The Chinese medicine composition of Example 1 or Example 2 can be made into medicinal wine for external use in treatment.

[0030] Then, the medicinal wine is prepared using Example 1 or Example 2, and its preparation comprises the following steps:

[0031] S1: Take each raw material according to the amount and crush them separately;

[0032] S2: Add the raw materials crushed in step S1 into 55-degree white wine and soak them for no less than 40 days, then filter and take the filtrate to obtain the medicinal wine.

[0033] Before preparing the medicinal wine, some drugs need to be processed to reduce or remove toxicity, such as black aconite root, stramonium, etc. This is a conventional technology in this field and will not be described in detail here.

[0034] When using, you can soak the medicinal wine in cotton cloth and apply it to the affected area; or apply it directly to the affected area for treatment.

[0035] Clinical data:

[0036] Since 2022, more than 300 patients with bone diseases have been treated with the present invention. The following is a retrospective summary of the treatment of patients with bone diseases treated with Example 1.

[0037] 178 patients with bone diseases were treated with the medicinal wine prepared in Example 1, including 93 males and 85 females, aged between 32 and 67 years old, of whom 27 patients suffered from cervical spondylosis only, 41 patients suffered from scapulohumeral periarthritis only, 16 patients suffered from rheumatoid arthritis only, 29 patients suffered from lumbar disc herniation only, and 6 patients suffered from bone spurs only, of whom 23 patients suffered from cervical spondylosis and bone hyperplasia simultaneously, 10 patients suffered from cervical spondylosis and lumbar muscle strain simultaneously, 15 patients suffered from rheumatoid arthritis and cervical spondylosis simultaneously, and 11 patients suffered from bone hyperplasia, cervical spondylosis, and lumbar muscle strain simultaneously.

[0038] The above patients all applied the medicinal wine prepared in Example 1 to the affected area 1-3 times a day, each time for not less than 40 minutes, for 15 consecutive days, and the therapeutic effect was statistically analyzed.

[0039] Different orthopedic diseases have different symptom manifestations. Before and after treatment, the TCM symptom scores of the above patients were calculated using the TCM symptom score table corresponding to the specific orthopedic disease. The TCM symptom score tables corresponding to cervical spondylosis, frozen shoulder, rheumatoid arthritis, bone hyperplasia / bone spurs, lumbar disc herniation, and lumbar muscle strain are shown in Tables 1 to 6 below, respectively.

[0040] Efficacy criteria:

[0041] Recovery: TCM syndrome score reduced by ≥95%;

[0042] Markedly effective: TCM syndrome score decreased by ≥70% and <95%;

[0043] Effective: TCM syndrome score decreased by ≥30% and <70%;

[0044] Ineffective: TCM syndrome score decreased by <30%.

[0045] Total effective rate = (cured + markedly effective + effective) × 100% / total number of cases.

[0046] Among patients with multiple bone diseases, if each disease meets the criteria for recovery, it will be recorded as recovered; if each disease meets the criteria for marked effect, it will be recorded as marked effect; if each disease meets the criteria for effectiveness, it will be recorded as effective. If any disease meets the criteria for ineffectiveness, it will be recorded as ineffective. If a disease meets two criteria, the one that meets the lower criteria will be regarded as effective. For example, if a patient suffers from two diseases at the same time, one meets the criteria for recovery and the other meets the criteria for marked effect, then this patient will be recorded as markedly effective.

[0047] The treatment results are as follows:

[0048] 43 people were cured, 68 people showed significant effect, 52 people were effective, and 15 people were ineffective, with an effective rate of 91.57%.

[0049] Table 1: TCM Syndrome Score Table for Cervical Spondylosis

[0050]

[0051] Table 2: TCM Syndrome Score Table for Periarthritis of Shoulder

[0052]

[0053] Table 3: TCM Syndrome Score Table for Rheumatoid Arthritis

[0054] Symptoms 0 points 1 point 2 points 3 points Redness, swelling, heat, and pain in joints —— Dull pain after exertion Persistent soreness tingling with radiation to the upper limbs Morning stiffness time ≤ 15 minutes 15-30 minutes 30-60 minutes >60 minutes Migratory pain Fixed pain ≤2 joints wandering 3-4 joints wandering ≥5 joints wandering Fever and thirst —— Low fever (<37.5°C) Moderate fever (37.5-38.5℃) High fever (>38.5°C) Tongue and pulse Light red and thin white fur Red and greasy tongue coating Crimson yellow and dry tongue coating Dark purple with little moss

[0055] Table 4: TCM Syndrome Score Table for Bone Hyperplasia / Bone Spur

[0056] Symptoms 0 points 1 point 2 points 3 points tingling in joints —— pain after exertion Persistent stinging Severe pain at night Friction in joints —— There is sound during activity Sound and pain Sound and movement disorders Weakness in waist and knees —— Occasional soreness and weakness Persistent soreness Need support when walking X-ray osteophyte size —— Osteophytes≤2mm Osteophytes 2-4 mm Osteophytes >4 mm

[0057] Table 5: TCM Syndrome Score Table for Lumbar Disc Herniation

[0058] Symptoms 0 points 1 point 2 points 3 points Low back pain radiating to lower limbs —— Dull pain after exertion Persistent soreness tingling with radiation to the upper limbs Straight Leg Raise Angle ＞70° 15-30 minutes 30-60 minutes >60 minutes Lower limb muscle strength Normal (Level 5) Level 4 Level 3 Level 0-2 Second function normal Weak urination Urinary retention incontinence

[0059] Table 6: TCM Syndrome Score Table for Lumbar Muscle Strain

[0060] Symptoms 0 points 1 point 2 points 3 points Lower back pain —— soreness after exertion Persistent soreness Stinging and refusing to press Range of tenderness —— 1 tender point 2-3 tender points widespread tenderness Limited activity normal Mild limitation in bending difficulty bending over Can't bend over Increased fatigue —— Worsened by prolonged sitting Standing for 30 minutes increases weight Worsened by slight activity

[0061] Typical cases:

[0062] The present invention has been used in numerous treatment cases, and generally has good effects. The following are some typical cases.

[0063] Case 1: Lumbar disc herniation (rehabilitation)

[0064] Zhang, male, 52 years old, diagnosed with lumbar disc herniation for 2 years, low back pain with radiating numbness of the left lower limb, difficulty walking (<100 meters), VAS pain score 7 points. MRI showed L4 / L5 intervertebral disc herniation. Oral non-steroidal drugs are not effective. Afterwards, the medicated wine prepared by Example 1 of the present invention was applied to the waist and affected limb every day for 30 minutes each time, and combined with mild massage treatment, at least 2 times a day. After 1 week, the pain was relieved (VAS 5 points), and the numbness was slightly reduced. After 4 weeks of continuous treatment, low back pain and numbness of lower limbs basically disappeared, the ability to walk was restored (can walk 500 meters continuously without discomfort), and the bending range of motion was significantly improved (up to 90 degrees). Follow up for 3 months, the symptoms did not recur, and the daily work and life were resumed.

[0065] Case 2: Knee osteoarthritis (significant improvement, functional recovery)

[0066] Li, female, 68 years old. She had a history of osteoarthritis of both knees for 5 years, and X-rays showed narrowing of the joint space and formation of osteophytes. She complained of persistent knee pain (VAS 6 points), stiffness, difficulty going up and down stairs, and needed crutches. She then applied the medicated wine prepared in Example 1 of the present invention to her knees and massaged them until they became hot, twice a day. After 2 weeks of treatment, the morning stiffness time was shortened, and the pain when walking on the ground was relieved (VAS 4 points). After 6 weeks of treatment, the pain was significantly relieved (VAS 2 points), she could walk without crutches, and only felt slight soreness when going up and down the stairs. After 12 weeks of treatment, she was able to carry out daily activities (buying groceries, taking a walk), and her joint mobility was close to normal. Her condition was stable during the six-month follow-up, and her quality of life was greatly improved.

[0067] Case 3: Rheumatoid frozen shoulder (symptoms completely recovered)

[0068] Lu, a 60-year-old female, suffered from rheumatoid periarthritis of the shoulder. She could not lift her hand when combing her hair. She applied the medicated wine prepared in Example 2 of the present invention to the affected area and combined it with mild massage. After one application, she felt her hand was much more relaxed. After daily treatment, she could put her hand halfway behind her back after three consecutive treatments. After one course of treatment (10 sessions), she could lift her hand completely. Her periarthritis of the shoulder was completely cured.

[0069] The present invention and its embodiments are described above. Such description is not restrictive. The embodiment shown in the embodiment is only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by the above, and does not deviate from the purpose of the invention, without creatively designing a structure and embodiment similar to the technical solution, they shall fall within the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for treating bone disease, characterized in that: By weight, it is composed of the following ingredients: 30-80 parts of processed Arisaema, 30-90 parts of processed Pinellia, 30-90 parts of raw Chuanwu, 30-50 parts of raw Kusnezoffii, 30-100 parts of natural copper, 30-100 parts of processed frankincense, 30-100 parts of myrrh, 30-100 parts of safflower, 12-90 parts of Chuanxiong, 30-90 parts of Chinese angelica, 30-90 parts of Zedoaria, 30-90 parts of Sanguisorba officinalis, and 30-90 parts of catechu , 30-100 parts of peach kernel, 30-90 parts of papaya, 30-90 parts of clematis, 15-100 parts of pepper, 30-90 parts of borneol, 20-50 parts of camphor, 30-90 parts of cinnamon bark, 30-90 parts of strychnine seeds, 30-90 parts of ground beetle, 30-90 parts of geranium, 30-90 parts of millennium jian, 30-100 parts of chuanxiong, 30-100 parts of liujiu 30-90 parts of rhizoma drynariae, 30-90 parts of realgar, 30-100 parts of cyathula, 30-90 parts of seven-leaf parsnip, 30-90 parts of datura, 30-90 parts of angelica dahurica, 30-90 parts of herba scutellariae, 30-90 parts of whole worm, 30-90 parts of snake, 30-90 parts of snake, 30-90 parts of pittosporum tobira, 30-90 parts of black aconite root, 30-90 parts of scutellariae, 30-90 parts of whole worm, 30-90 parts of snake ... pittosporum tobira bark, 30-90 parts of black aconite root. 0 parts, 30-90 parts of Herba Lycopodii, 30-90 parts of Radix Asari, 30-90 parts of Rhizoma Et Rhizoma, 30-100 parts of Radix Angelicae Dahuricae, 30-100 parts of Radix Saposhnikoviae, 30-100 parts of Cibotium bark, 30-50 parts of Rhubarb, 30-50 parts of Sappan Wood, 30-90 parts of Salvia miltiorrhizae, 30-90 parts of Black Ant, 30-90 parts of Herba Ephedrae, 30-90 parts of Radix Et Rhizoma, and 30-90 parts of Ephedrae.

2. A Chinese medicine composition for treating bone disease according to claim 1, characterized in that: By weight, it is composed of the following ingredients: 45 parts of processed Arisaema, 45 parts of processed Pinellia, 30 parts of raw Chuanwu, 30 parts of raw Kusnezoffii, 45 parts of natural copper, 40 parts of processed frankincense, 35 parts of myrrh, 50 parts of safflower, 35 parts of Chuanxiong, 40 parts of angelica, 30 parts of Zedoaria, 40 parts of Sanguisorba officinalis, 35 parts of catechu, 45 parts of peach kernel, 35 parts of papaya, 45 parts of clematis, 25 parts of Zanthoxylum bungeanum, 30 parts of borneol, 25 parts of camphor, 30 parts of cinnamon bark, 45 parts of raw Strychnos nux vomica, 35 parts of Eupolyphaga sinensis, 40 parts of Geranium, 35 parts of Millennium scutellaria, 35 parts of Dipsacus asper, and 30 parts of Achyranthes bidentata , 45 parts of Drynaria fortunei, 40 parts of realgar, 45 parts of Cyathula, 45 parts of Seven-leaf Parsley, 40 parts of Datura, 40 parts of Angelica dahurica, 45 parts of Herba striatae, 45 parts of Herba scutellariae, 35 parts of Scolopendra, 30 parts of Whole Insects, 35 parts of Snake, 35 parts of Snake, 40 parts of Cortex Pittosporume, 50 parts of Aconite, 40 parts of Herba Lycopodii, 45 parts of Caulis Aconiti Lateralis Preparata, 35 parts of Asarum, 45 parts of Notopterygium, 45 parts of Angelica dahurica, 40 parts of Saposhnikovia divaricata, 35 parts of Cibotium barometz, 30 parts of Rhubarb, 30 parts of Sappan Wood, 35 parts of Salvia miltiorrhiza, 35 parts of Black Ant, 40 parts of Herba Ephedrae, and 40 parts of Ephedra sinica.

3. A Chinese medicine composition for treating bone disease according to claim 1, characterized in that: By weight, it is composed of the following ingredients: 30 parts of processed Arisaema, 35 parts of processed Pinellia, 45 parts of raw Chuanwu, 45 parts of raw Kusnezoffii, 50 parts of natural copper, 35 parts of processed frankincense, 35 parts of myrrh, 45 parts of safflower, 40 parts of Chuanxiong, 45 parts of Chinese angelica, 40 parts of Zedoaria, 35 parts of Sanguisorba officinalis, 35 parts of catechu, 55 parts of peach kernel, 45 parts of papaya, 45 parts of clematis, 25 parts of Zanthoxylum bungeanum, 30 parts of borneol, 25 parts of camphor, 30 parts of cinnamon bark, 35 parts of raw Strychnos nux vomica, 35 parts of Eupolyphaga sinensis, 45 parts of Geranium, 40 parts of Millennium scutellaria, 35 parts of Dipsacus asper, and 45 parts of Achyranthes bidentata , 50 parts of Drynaria Rhizoma, 40 parts of Realgar, 45 parts of Cyathula, 40 parts of Seven-leaf Parsley, 45 parts of Datura, 40 parts of Angelicae Pubescentis, 45 parts of Herba Scutellariae, 40 parts of Scolopendra, 35 parts of Whole Insects, 30 parts of Snake, 35 parts of Snake, 30 parts of Pittosporum tobira, 40 parts of Black Aconite, 40 parts of Herba Lycopodii, 40 parts of Caulis Aconiti Lateralis Preparata, 40 parts of Asarum, 40 parts of Notopterygium, 30 parts of Angelicae Dahuricae, 40 parts of Saposhnikovia divaricata, 45 parts of Cibotium barometz, 35 parts of Rhubarb, 30 parts of Sappan Wood, 45 parts of Salvia miltiorrhiza, 45 parts of Black Ant, 40 parts of Herba Ephedrae, and 35 parts of Ephedra.

4. Use of the traditional Chinese medicine composition for treating bone diseases according to any one of claims 1 to 3 in preparing external medicines for treating bone diseases.

5. The use according to claim 4, characterized in that The bone diseases include cervical spondylosis, periarthritis of the shoulder, rheumatoid arthritis, bone hyperplasia, bone spurs, lumbar disc herniation, and lumbar muscle strain.

6. A medicinal wine for treating bone diseases, characterized in that: The bone disease-treating Chinese medicine composition is prepared from the Chinese medicine composition for treating bone diseases according to any one of claims 1 to 3.

7. The medicinal wine for treating bone diseases according to claim 6, characterized in that: Its preparation comprises the following steps: S1: Take each raw material according to the amount and crush them separately; S2: adding the raw materials crushed in step S1 into white wine and soaking them for not less than 40 days, filtering and taking the filtrate to obtain the medicinal wine.

8. The medicinal wine for treating bone diseases according to claim 7, characterized in that: The alcohol content of the liquor in step S2 is above 45 degrees.

Images