Multi-wavelength optical fiber imaging device and system

Abstract

The invention relates to the technical field of biomedical imaging, in particular to a multi-wavelength optical fiber imaging device and system, and aims to solve the problem that an existing optical fiber imaging system obtains less imaging wavelength information. The multi-wavelength optical fiber imaging device comprises a plurality of transmission optical fibers, a scanner and an objective lens, a plurality of first light beams with different wavelengths can be transmitted to the scanner by arranging the transmission optical fibers with different specifications, the scanner changes the propagation direction of the first light beams with different wavelengths and scans a target tissue, and the target tissue is obtained. The plurality of first light beams of different wavelengths are focused on the target tissue by the objective lens so as to image the target tissue. According to the multi-wavelength optical fiber imaging device, respective transmission of multiple first light beams with different wavelengths is realized, the wavelength range of the working light beams transmitted by the imaging device is expanded, and the multiple first light beams with different wavelengths are used for imaging the target tissue, so that more imaging information of the target tissue is provided, and the imaging requirements of complex application scenes are met.

Description

Technical Field

[0001] The present application relates to the field of biomedical imaging technology, and in particular to a multi-wavelength fiber optic imaging device and system. Background Art

[0002] Fiber optic imaging systems transmit illumination or imaging light through optical fibers. The flexible light transmission characteristics of optical fibers allow fiber optic imaging systems to penetrate deep into the human body or animal body for endoscopic imaging, or to realize wearable or handheld optical imaging system designs. Remote scanning fiber optic imaging systems utilize optical fibers to transmit illumination and imaging light energy, and utilize mechanical or optical scanning devices located at the remote end to achieve two-dimensional or three-dimensional scanning imaging. They have advantages such as high resolution, low crosstalk, and high flexibility. In addition, fiber optic imaging systems have been combined with imaging technologies such as confocal imaging, optical coherence tomography, and multiphoton imaging to develop a series of imaging technologies such as fiber confocal imaging, fiber multiphoton imaging, and fiber optical coherence tomography, becoming a powerful tool for scientific research and disease diagnosis in the fields of life sciences and medicine.

[0003] However, the imaging wavelength information obtained by existing fiber optic imaging systems is limited and cannot meet the higher requirements of modern scientific research and clinical diagnosis for imaging wavelength information. Summary of the Invention

[0004] In view of this, embodiments of the present application provide a multi-wavelength fiber optic imaging device and system based on multi-channel fiber optic transmission to solve the problem that existing fiber optic imaging systems obtain less imaging wavelength information.

[0005] In a first aspect, an embodiment of the present application provides a multi-wavelength fiber optic imaging device, comprising: a plurality of transmission optical fibers, each of which is used to transmit a plurality of first light beams, the wavelength of the first light beam transmitted by each transmission optical fiber being different, the first end of the transmission optical fiber being used to receive the first light beam, and the second end of the transmission optical fiber being used to output the first light beam; a scanner, located on the first light beam output side of the plurality of transmission optical fibers, for receiving the first light beams transmitted by the second ends of the plurality of transmission optical fibers, and changing the propagation direction of the plurality of first light beams so as to use the plurality of first light beams to scan the target tissue; an objective lens, located on the first light beam output side of the scanner, for focusing the plurality of first light beams on the target tissue so as to image the target tissue.

[0006] In combination with the first aspect, in certain implementations of the first aspect, the multi-wavelength fiber imaging device further includes: a collimating optical element located between the multiple transmission optical fibers and the scanner, for collimating the first light beams output from the second ends of the multiple transmission optical fibers.

[0007] In combination with the first aspect, in certain implementations of the first aspect, the collimating optical element includes a first collimating lens, which is located between the multiple transmission optical fibers and the scanner, and is used to collimate the first light beams output from the second ends of the multiple transmission optical fibers; wherein the first collimating lens has multiple first focal points located on the first principal optical axis, and the multiple first focal points correspond one-to-one to the multiple first light beams, respectively. The second ends of the transmission optical fibers corresponding to the first light beams are located at the first focal points corresponding to the same first light beam, so that the propagation directions of the multiple first light beams emitted by the first collimating lens are parallel.

[0008] In combination with the first aspect, in some implementations of the first aspect, the first collimating lens includes a lens and / or a lens group having an Abbe number less than a preset value, so as to increase the distance between adjacent first focal points.

[0009] In combination with the first aspect, in certain implementations of the first aspect, the multi-wavelength fiber optic imaging device further includes: a first beam-combining optical element, located between the first collimating lens and the scanner, the first beam-combining optical element having a first refractive surface and a second refractive surface parallel to each other, when multiple first light beams with parallel propagation directions propagate to the first refractive surface, the incident angle of the first light beam is greater than 0° and less than 90°, the multiple first light beams can enter the first beam-combining optical element from the first refractive surface and be emitted from the first beam-combining optical element from the second refractive surface, and after the multiple first light beams are emitted from the second refractive surface, the propagation directions of the multiple first light beams coincide.

[0010] In combination with the first aspect, in certain implementations of the first aspect, the multi-wavelength fiber imaging device also includes: a second beam-combining optical element, located between the first collimating lens and the scanner, the second beam-combining optical element including a plurality of first optical film layers that are parallel to each other and spaced apart, the plurality of first optical film layers corresponding one-to-one to the plurality of first light beams, each first optical film layer capable of reflecting the corresponding first light beam and transmitting the first light beams other than the corresponding first light beam, so that each first light beam can reach the corresponding first optical film layer, and after the plurality of first light beams are respectively reflected by the corresponding first optical film layers, the propagation directions of the plurality of first light beams coincide.

[0011] In combination with the first aspect, in certain implementations of the first aspect, the collimating optical element includes a second collimating lens, which is located between the multiple transmission optical fibers and the scanner, and is used to collimate the first light beams output from the second ends of the multiple transmission optical fibers, and the second collimating lens has a second principal optical axis; wherein, the extension direction of the rotation axis of the light cone formed by the first light beam emitted from the second end of each transmission optical fiber can be parallel to or coincide with the extension direction of the second principal optical axis; the second collimating lens has multiple second focal points and multiple focal planes, the multiple second focal points correspond one-to-one to the multiple first light beams, each focal plane contains a second focus, and the second end of the transmission optical fiber corresponding to the first light beam is located in the focal plane corresponding to the same first light beam.

[0012] In combination with the first aspect, in certain implementations of the first aspect, the multi-wavelength fiber imaging device also includes: a third beam-combining optical element, located between the second collimating lens and the scanner, the third beam-combining optical element including a plurality of second optical film layers, the normals of the plurality of second optical film layers being arranged to cross each other, the plurality of second optical film layers corresponding one-to-one to the plurality of first light beams, each second optical film layer being capable of reflecting the corresponding first light beam and transmitting the first light beams other than the corresponding first light beam, so that each first light beam can reach the corresponding second optical film layer, and after the plurality of first light beams are respectively reflected by the corresponding second optical film layers, the propagation directions of the plurality of first light beams coincide.

[0013] In combination with the first aspect, in certain implementations of the first aspect, the multiple first light beams have respective corresponding field of view ranges, and the field of view range of the multi-wavelength fiber optic imaging device is the intersection of the respective corresponding field of view ranges of the multiple first light beams.

[0014] In combination with the first aspect, in certain implementations of the first aspect, the multi-wavelength fiber optic imaging device further includes: a probe having a receiving space for receiving the second ends of the plurality of transmission optical fibers, the scanner, and the objective lens.

[0015] In a second aspect, an embodiment of the present application provides a multi-wavelength fiber optic imaging system, comprising: a multi-wavelength fiber optic imaging device as mentioned in any one of the first aspects; a plurality of light sources, respectively located on the first light beam receiving sides of a plurality of transmission optical fibers, for respectively providing first light beams with different wavelengths to the first ends of the plurality of transmission optical fibers.

[0016] In combination with the second aspect, the multi-wavelength fiber imaging system further includes: at least one coupler, located between the multiple light sources and the first ends of the corresponding transmission optical fibers, for coupling the first light beam provided by at least one light source to the first end of the corresponding transmission optical fiber.

[0017] The multi-wavelength fiber optic imaging device provided in this embodiment includes multiple transmission optical fibers, a scanner, and an objective lens. By providing multiple transmission optical fibers of varying specifications, multiple first light beams of different wavelengths can be transmitted to the scanner. The scanner changes the propagation direction of the multiple first light beams of different wavelengths and scans the target tissue. The multiple first light beams of different wavelengths can be focused on the target tissue by the objective lens to image the target tissue. The multi-wavelength fiber optic imaging device enables the separate transmission of multiple first light beams of different wavelengths, expanding the wavelength range of the operating light beams transmitted by the multi-wavelength fiber optic imaging device. It utilizes multiple first light beams of different wavelengths to image the target tissue, providing more imaging information of the target tissue and meeting the imaging requirements of complex application scenarios. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The above and other purposes, features, and advantages of the present application will become more apparent through a more detailed description of the embodiments of the present application in conjunction with the accompanying drawings. The accompanying drawings are intended to provide a further understanding of the embodiments of the present application and constitute a part of the specification. Together with the embodiments of the present application, they are used to explain the present application and do not constitute a limitation of the present application. In the drawings, the same reference numerals generally represent the same components or steps.

[0019] Figure 1 The figure shows a structural diagram of an application scenario of a multi-wavelength fiber optic imaging device provided by an embodiment of the present application.

[0020] Figure 2 Shown is a structural schematic diagram of an application scenario of a multi-wavelength fiber optic imaging device provided by another embodiment of the present application.

[0021] Figure 3 The figure shows a structural diagram of an application scenario suitable for a transmission optical fiber and a first collimating lens provided by an embodiment of the present application.

[0022] Figure 4 Shown is a structural schematic diagram of an application scenario of a multi-wavelength fiber optic imaging device provided by another embodiment of the present application.

[0023] Figure 5 The figure shows a structural diagram of an application scenario applicable to the first beam-combining optical element provided by an embodiment of the present application.

[0024] Figure 6 The figure shows a structural diagram of an application scenario of a second beam-combining optical element provided by an embodiment of the present application.

[0025] Figure 7 The figure shows a structural diagram of an application scenario suitable for a transmission optical fiber and a second collimating lens provided by an embodiment of the present application.

[0026] Figure 8 Shown is a structural schematic diagram of an application scenario of a multi-wavelength fiber optic imaging device provided by yet another embodiment of the present application.

[0027] Figure 9 The figure shows a structural diagram of an application scenario applicable to the third beam-combining optical element provided by an embodiment of the present application.

[0028] Figure 10 FIG2 is a schematic diagram showing the field of view of a multi-wavelength fiber optic imaging device provided in one embodiment of the present application.

[0029] Figure 11 The figure shows a structural diagram of an application scenario of a multi-wavelength fiber optic imaging system provided by an embodiment of the present application.

[0030] Figure 12 The figure shows a schematic structural diagram of an application scenario suitable for transmission optical fiber and light source provided by an embodiment of the present application.

[0031] Reference numerals:

[0032] 1. Multi-wavelength fiber imaging system; 10. Multi-wavelength fiber imaging device; 11. Transmission fiber; 110. First end of transmission fiber; 111. Second end of transmission fiber; 112. First light beam output side of transmission fiber; 113. First light beam receiving side of transmission fiber; 114. Second end of transmission fiber; 115. First end of transmission fiber; 12. Scanner; 120. First light beam output side; 13. Objective lens; 14. Collimating optical element; 140. First collimating lens; 1400. First focus; 141. Second collimating lens; 1410. Second focus; 15. First beam combining optical element; 150. First refractive surface; 151. Second refractive surface; 16. Second beam combining optical element; 160. First optical film layer; 17. Third beam combining optical element; 170. Second light 1. Optical film layer; 18. Probe; 180. Accommodation space; 19. First optical fiber ferrule; 20. First light beam; 200. First field of view; 201. Second field of view; 202. Third field of view; 203. Field of view of multi-wavelength optical fiber imaging device; 30. Target tissue; 40. Light source; 50. Coupler; 60. Second optical fiber ferrule; 70. Reflector; 80. Light modulator; 90. Second light beam; 91. Second light beam collection module; 910. Spectrum splitter; 911. Photoelectric conversion module; 912. Focusing lens; 92. Host; L1. First principal optical axis; L2. Second principal optical axis; L3. Rotation axis. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0034] Fiber optic imaging systems transmit illumination or imaging light through optical fibers. The flexible light transmission characteristics of optical fibers allow fiber optic imaging systems to penetrate deep into the human body or animal body for endoscopic imaging, or to realize wearable or handheld optical imaging system designs. Remote scanning fiber optic imaging systems utilize optical fibers to transmit illumination and imaging light energy, and utilize mechanical or optical scanning devices located at the remote end to achieve two-dimensional or three-dimensional scanning imaging. They have advantages such as high resolution, low crosstalk, and high flexibility. In addition, fiber optic imaging systems have been combined with imaging technologies such as confocal imaging, optical coherence tomography, and multiphoton imaging to develop a series of imaging technologies such as fiber confocal imaging, fiber multiphoton imaging, and fiber optical coherence tomography, becoming a powerful tool for scientific research and disease diagnosis in the fields of life sciences and medicine.

[0035] However, existing fiber optic imaging devices mainly rely on a single wavelength of light beam to illuminate the target tissue for imaging, and can only obtain imaging information of the target tissue at this wavelength. As a result, the imaging information obtained by the fiber optic imaging device is limited, which restricts the in-depth understanding and analysis of the target tissue and cannot meet the higher demands of modern scientific research and clinical diagnosis for imaging information.

[0036] In response to the above problems, the present application provides a multi-wavelength fiber optic imaging device based on multi-channel fiber optic transmission to provide an imaging tool for scientific research and clinical diagnosis that can obtain more imaging information.

[0037] Figure 1 The figure shows a structural diagram of an application scenario of a multi-wavelength fiber optic imaging device provided by an embodiment of the present application. Figure 2 The figure shows a schematic diagram of a structure of an application scenario of a multi-wavelength optical fiber imaging device provided by another embodiment of the present application. Figure 1 and Figure 2 The multi-wavelength fiber optic imaging device provided in this embodiment is described in detail. The multi-wavelength fiber optic imaging device 10 includes: a plurality of transmission optical fibers 11, a scanner 12 and an objective lens 13.

[0038] The plurality of transmission optical fibers 11 are respectively used to transmit a plurality of first light beams 20. Each transmission optical fiber 11 transmits a first light beam 20 of a different wavelength. The first end 110 of the transmission optical fiber is used to receive the first light beam 20, and the second end 111 of the transmission optical fiber is used to output the first light beam 20.

[0039] Specifically, the transmission optical fiber 11 is used to transmit the first light beam 20. Multiple transmission optical fibers 11 can respectively transmit the first light beam 20 in multiple spectral ranges. The transmission optical fiber 11 can transmit the first light beam 20 from a first end 110 of the transmission optical fiber to a second end 111 of the transmission optical fiber. Exemplarily, the first end and the second end of the transmission optical fiber can both be the ends of the transmission optical fiber.

[0040] Exemplarily, the first light beam can serve as illumination light or excitation light. Exemplarily, the first light beam can be visible light or invisible light. Exemplarily, the first light beam can be a red light beam, a blue light beam, or a green light beam. Exemplarily, the number of transmission optical fibers can be the same as the number of wavelength types of the first light beam. Each wavelength corresponds to a wavelength type.

[0041] For example, the material and structure of the transmission optical fiber can be selected based on the wavelength of the first light beam to be transmitted. For example, the transmission optical fiber can include a quartz optical fiber or a composite optical fiber. For example, the transmission optical fiber can be a composite optical fiber comprising a plastic cladding and a liquid core. For example, the transmission optical fiber can include a liquid optical waveguide. For example, the transmission optical fiber can include a hollow-core optical fiber. For example, the specifications of multiple transmission optical fibers can differ from each other.

[0042] The scanner 12 is located at the first beam output side 112 of the multiple transmission optical fibers, and is used to receive the first beams 20 transmitted by the second ends 111 of the multiple transmission optical fibers, and change the propagation directions of the multiple first beams 20 to scan the target tissue 30 using the multiple first beams 20.

[0043] Specifically, the first light beam output side 112 of the transmission optical fiber is the side of the transmission optical fiber 11 for emitting the first light beam 20. Further, the first light beam output side 112 of the transmission optical fiber is the side of the second end 111 of the transmission optical fiber for emitting the first light beam 20. The first light beams 20 emitted by multiple transmission optical fibers 11 can all be received by the scanner 12. Exemplarily, the first light beams emitted by all transmission optical fibers can all be received by the scanner 12. Exemplarily, the scanner 12 performs a two-dimensional plane scan or a three-dimensional stereo scan on the target tissue by changing the emission angle of the first light beam. Exemplarily, the scanner 12 may include a mechanical scanner. For example, the scanner may include a motor and a galvanometer or a rotating mirror. Exemplarily, the scanner 12 may also include an optical scanner. For example, the scanner may include a prism, a grating, an acousto-optic crystal, or an electro-optic crystal.

[0044] The objective lens 13 is located at the first light beam output side 120 of the scanner, and is used to focus the multiple first light beams 20 on the target tissue 30 to image the target tissue 30 .

[0045] Specifically, the first light beam output side 120 of the scanner is the side of the scanner 12 for emitting the first light beam 20. For example, the objective lens can be a lens assembly composed of a plurality of lenses, or a single lens. For example, the objective lens is used to focus the first light beam on the target tissue. For example, the target tissue can include biological tissue.

[0046] In some application scenarios, after receiving the first light beams 20 transmitted by the second ends 111 of the multiple transmission optical fibers, the scanner 12 can change the propagation direction of the first light beams 20 in both the tilt and pitch directions, thereby using the multiple first light beams 20 to scan one or more two-dimensional planes of the target tissue 30. The objective lens 13 focuses the multiple first light beams 20 on the scanned two-dimensional plane to form an image of the target tissue 30.

[0047] In some application scenarios, refer to Figure 1 The multi-wavelength fiber optic imaging device 10 may include three transmission optical fibers 11. The first light beam 20 is a red light beam, a blue light beam, or a green light beam. The three transmission optical fibers 11 transmit the red light beam, the blue light beam, and the green light beam, respectively. The red light beam, the blue light beam, and the green light beam are all received by the scanner 12. The scanner 12 uses the red light beam, the blue light beam, and the green light beam to scan the target tissue 30 at the same time. The objective lens 13 outputs the red light beam, the blue light beam, and the green light beam to the target tissue 30 at the same time. The multi-wavelength fiber optic imaging device 10 can make the red light beam, the blue light beam, and the green light beam irradiate the target tissue 30 at the same time, realize multi-color imaging of the target tissue 30, and thus provide more imaging information.

[0048] In some application scenarios, the target tissue may include multiple sub-target tissues. Different sub-target tissues can be labeled with fluorescent dyes with different excitation or emission wavelengths. A multi-wavelength fiber optic imaging device directs multiple first beams of different wavelengths toward the target tissue, capturing the distribution of each sub-target tissue and, therefore, the tissue structure of the target tissue, providing more structural information and diagnostic evidence for scientific research or clinical disease diagnosis.

[0049] In some application scenarios, multiple first light beams of different wavelengths reach the target tissue through a scanner and an objective lens, the target tissue can provide feedback to the multiple first light beams of different wavelengths, and multiple second light beams of different wavelengths are emitted by the target tissue. In some implementations, the objective lens is also used to receive multiple second light beams of different wavelengths. The multi-wavelength fiber optic imaging device may also include a dichroic mirror and an imaging fiber. The dichroic mirror is located between the objective lens and the scanner, and is capable of transmitting multiple first light beams and reflecting multiple second light beams. One end of the imaging fiber is located on the second light beam output side of the dichroic mirror, and is used to receive the multiple second light beams reflected by the dichroic mirror. The other end of the imaging fiber is used to output the multiple second light beams from the dichroic mirror so that the multiple second light beams can be collected. In other implementations, the multiple second light beams can be collected after passing through the objective lens, the scanner, and the multiple transmission fibers in sequence.

[0050] Exemplarily, the multi-wavelength fiber optic imaging device further includes one or more fiber optic sleeves. One fiber optic sleeve can be sleeved on the outside of one or more transmission optical fibers.

[0051] Exemplarily, the multi-wavelength fiber imaging device can be a multi-wavelength fiber imaging device based on multi-path fiber transmission.

[0052] The multi-wavelength fiber imaging device provided in the embodiment includes a plurality of transmission fibers, a scanner, and an objective lens. By arranging a plurality of transmission fibers with different specifications, a plurality of first light beams with different wavelengths can be transmitted to the scanner respectively. The scanner changes the propagation directions of the plurality of first light beams with different wavelengths and scans a target tissue. The plurality of first light beams with different wavelengths can be focused on the target tissue by the objective lens to image the target tissue. The multi-wavelength fiber imaging device realizes the separate transmission of the plurality of first light beams with different wavelengths, expands the wavelength range of the working light beams transmitted by the multi-wavelength fiber imaging device, and uses the plurality of first light beams with different wavelengths to image the target tissue to provide more imaging information of the target tissue and meet the imaging requirements of complex application scenarios.

[0053] In some embodiments, as shown in Figure 1 and Figure 2 The multi-wavelength fiber imaging device 10 further includes a collimating optical element 14. The collimating optical element 14 is located between the plurality of transmission fibers 11 and the scanner 12 and is configured to collimate the first light beams 20 output by the second ends 111 of the plurality of transmission fibers.

[0054] Specifically, the collimating optical element 14 can collimate the first light beams 20 output by the plurality of transmission fibers 11. Exemplarily, the collimating optical element 14 can collimate the first light beams 20 output by all the transmission fibers 11. Exemplarily, the collimating optical element can include a lens or a lens group. Exemplarily, the collimating optical element can include an achromatic cemented lens.

[0055] Exemplarily, the collimating optical element can have two opposite sides. The second ends of the plurality of transmission fibers can be located at one side of the collimating optical element, and the scanner can be located at the other side of the collimating optical element.

[0056] The multi-wavelength fiber imaging device provided in the embodiment further includes a collimating optical element located between the plurality of transmission fibers and the scanner. The collimating optical element can collimate the first light beams output by the plurality of transmission fibers, which is conducive to simplifying the structure of the multi-wavelength fiber imaging device and reducing the structural complexity of the multi-wavelength fiber imaging device.

[0057] Figure 3 FIG. 6 shows a structure diagram of an application scenario of the transmission fiber and the first collimating lens according to an embodiment of the present application. Figure 4 FIG. 7 shows a structure diagram of an application scenario of the multi-wavelength fiber imaging device according to another embodiment of the present application.

[0058] In some embodiments, as shown in Figures 2 to 4 As shown, the collimating optical element 14 includes a first collimating lens 140. The first collimating lens 140 is located between the plurality of transmission optical fibers 11 and the scanner 12 and is used to collimate the first light beams 20 output from the second ends 111 of the plurality of transmission optical fibers. The first collimating lens 140 has a first principal optical axis L1.

[0059] The first collimating lens 140 has multiple first focal points 1400 located along the first principal optical axis L1. Each of the multiple first focal points 1400 corresponds to a plurality of first light beams 20. The second end 111 of the transmission optical fiber corresponding to each first light beam 20 is located at the first focal point 1400 corresponding to the same first light beam 20, so that the propagation directions of the multiple first light beams 20 emitted by the first collimating lens 140 are parallel. Specifically, after being collimated by the first collimating lens 140, the propagation directions of the multiple first light beams 20 are all parallel to the first principal optical axis L1. The multiple first light beams 20 have the same beam direction.

[0060] Specifically, the second end 111 of the transmission optical fiber can be the terminal end of the transmission optical fiber 11. Because the wavelengths of the multiple first light beams 20 are different, different first light beams 20 correspond to different first focal points 1400. The multiple first focal points 1400 are all located on the first principal optical axis L1 and are spaced apart along the first principal optical axis L1 of the first collimating lens 140. The first light beams 20 output from the second ends 111 of the multiple transmission optical fibers are directed from the corresponding first focal points 1400 toward the first collimating lens 140, thereby achieving collimation of the multiple first light beams 20.

[0061] Exemplarily, the second end 111 of the transmission optical fiber may be an end face of the distal end of the transmission optical fiber 11. The center point of the end face is located at the first focus 1400.

[0062] For example, Figure 3 As shown, the first collimating lens 140 may have two sides disposed opposite to each other, the second ends 111 of the plurality of transmission optical fibers may be located on one side of the first collimating lens 140, and the scanner 12 may be located on the other side of the first collimating lens 140. The plurality of first focal points 1400 and the second ends 111 of the plurality of transmission optical fibers may be located on the same side of the first collimating lens 140.

[0063] For example, Figure 3As shown, in each transmission optical fiber 11, the second end 111 of the transmission optical fiber can be the end of the second end portion 114 of the transmission optical fiber. The extension directions of the second end portions 114 of the multiple transmission optical fibers can be parallel to each other. The extension direction of the second end portion 114 of the transmission optical fiber can be arranged to cross the extension direction of the first principal optical axis L1. The extension directions of the second end portions 114 of the multiple transmission optical fibers are parallel to each other, which is beneficial to reducing the overall circumferential size of the second end portions 114 of the multiple transmission optical fibers, so that the circumferential size of the multi-wavelength optical fiber imaging device 10 can be set smaller, and is beneficial to reducing the total area of ​​the light spots corresponding to the multiple first light beams 20, so that the volume of the first collimating lens 140 can be set smaller and can also meet the requirements of collimating the multiple first light beams 20, which is beneficial to reducing the volume and weight of the multi-wavelength optical fiber imaging device 10.

[0064] For example, Figure 3 As shown, the multi-wavelength fiber optic imaging system 1 may further include a first fiber optic ferrule 19. The second ends 114 of the plurality of transmission optical fibers may be inserted into the same first fiber optic ferrule 19. This secures the second ends 111 of the plurality of transmission optical fibers and helps reduce the overall circumferential size of the second ends 114 of the plurality of transmission optical fibers.

[0065] For example, Figure 3 As shown, on a plane passing through the centerline of the second end 114 of the transmission fiber and the first principal optical axis L1, the orthographic projection of the second end 114 of the transmission fiber is located on one side of the first principal optical axis L1, while the orthographic projection of the first collimating lens 140 is located on the other side of the first principal optical axis L1. With this arrangement, the first light beams 20 transmitted by the multiple transmission fibers 11 can be emitted toward the same side of the first principal optical axis L1 on the plane passing through the centerline of the second end 114 of the transmission fiber and the first principal optical axis L1. This allows the first collimating lens 140 to retain only the portion located on the other side of the first principal optical axis L1, thus reducing its size. For example, on a plane perpendicular to the first principal optical axis L1, the orthographic projection of the first collimating lens 140 can be fan-shaped. For example, the first collimating lens 140 can be formed by cutting a conventional collimating lens. The first collimating lens 140 can be the portion of the conventional collimating lens that is intended to be passed through by the multiple first light beams 20.

[0066] For example, Figure 4As shown, the multiple first light beams 20 can pass through the first collimating lens 140, the scanner 12, and the objective lens 13 in sequence before reaching the target tissue 30. In other words, the multiple first light beams 20 collimated by the first collimating lens 140 do not need to be combined before reaching the target tissue 30. This arrangement is conducive to simplifying the structure of the multi-wavelength fiber optic imaging device, reducing the volume and weight of the multi-wavelength fiber optic imaging device, so that the multi-wavelength fiber optic imaging device can meet the requirements of miniaturization and lightweight, and the multi-wavelength fiber optic imaging device can be suitable for application scenarios with high requirements on volume and weight. For example, the multi-wavelength fiber optic imaging device can be used as an endoscope to observe the internal cavity of animals or humans.

[0067] In the multi-wavelength fiber imaging device provided in this embodiment, the first collimating lens serves as a collimating optical element to collimate the first light beams transmitted by the multiple transmission optical fibers. Since the wavelengths of the multiple first light beams are different, the different first light beams correspond to different first focal points of the first collimating lens. The second end of the transmission optical fiber corresponding to the first light beam is positioned at the first focal point corresponding to the same first light beam, thereby achieving collimation of the first light beams transmitted by the multiple transmission optical fibers, and making the beam pointing angles of the multiple first light beams collimated by the first collimating lens the same, and the propagation directions of the multiple first light beams are parallel, which is beneficial for the multiple first light beams collimated by the first collimating lens to be able to image the target tissue without being combined.

[0068] In some embodiments, the first collimating lens 140 may include a lens having an Abbe number less than a preset value to increase the distance between adjacent first focal points 1400. The first collimating lens 140 may also include a lens group to increase the distance between adjacent first focal points 1400.

[0069] Since the first collimating lens includes a lens having an Abbe number less than a preset value, or is formed by a lens group, the dispersion of the first collimating lens can be enhanced to increase the spacing between adjacent first focal points so that the second end of the transmission optical fiber has sufficient physical space for arrangement.

[0070] For example, the preset value may be less than or equal to 60. For example, the first collimating lens may include a lens having an Abbe number less than or equal to 60. For example, the Abbe number of the lens included in the first collimating lens may be 30, 40, or 60. For example, the first collimating lens may be an aspheric lens.

[0071] Exemplarily, the first collimating lens may include a lens group, and the lens group may be formed by fixing a plurality of lenses made of different materials through a mechanical structure or by gluing.

[0072] Figure 5 FIG2 is a schematic diagram of a structure of an application scenario of a first beam combining optical element provided by an embodiment of the present application. Figure 2 and Figure 5The multi-wavelength fiber imaging device 10 further includes a first beam combining optical element 15 .

[0073] The first beam-combining optical element 15 is located between the first collimating lens 140 and the scanner 12. The first beam-combining optical element 15 has a first refractive surface 150 and a second refractive surface 151 that are parallel to each other. When multiple first light beams 20 with parallel propagation directions propagate to the first refractive surface 150, the incident angle of the first light beams 20 is greater than 0° and less than 90°. The multiple first light beams 20 can enter the first beam-combining optical element 15 through the first refractive surface 150 and exit the first beam-combining optical element 15 through the second refractive surface 151. After exiting the second refractive surface 151, the propagation directions of the multiple first light beams 20 coincide.

[0074] In some application scenarios, such as Figure 5 As shown, after being collimated by the first collimating lens 140, the multiple first light beams 20 have the same beam direction, the propagation directions of the multiple first light beams 20 are parallel and do not overlap, and the centroids of the light spots corresponding to the multiple first light beams 20 are slightly spaced apart and do not overlap. Because the incident angle of the first light beams 20 when propagating to the first refractive surface 150 is greater than 0° and less than 90°, the first light beams 20 can be refracted when entering the first beam-combining optical element 15 from the first refractive surface 150. Because the first refractive surface 150 and the second refractive surface 151 are parallel, the first light beams 20 will experience lateral displacement when emitting from the first beam-combining optical element 15.

[0075] Because the wavelengths of the multiple first light beams 20 differ, the first beam-combining optical element 15 has different refractive indices for the first light beams 20 of different wavelengths. After the multiple first light beams 20 enter the first beam-combining optical element 15 via the first refractive surface 150 and exit the first beam-combining optical element 15 via the second refractive surface 151, the multiple first light beams 20 have different lateral displacements. This allows the centroids of the beam spots corresponding to the multiple first light beams 20 to coincide, and the propagation directions of the multiple first light beams 20 to coincide, thereby achieving beam combining of the multiple first light beams 20.

[0076] Exemplarily, the first beam-combining optical element may include one or more optical glass plates. Exemplarily, the propagation directions of the multiple first light beams may be made to coincide by adjusting one or more of factors, such as the angle between the first light beam and the first refractive surface, the distance between the second refractive surface and the first refractive surface, and the refractive index and dispersion characteristics of the first beam-combining optical element. Exemplarily, the number of first light beams with different wavelengths is two. The centroid of the light spots of the two collimated light beams formed by the two first light beams may be adjusted by adjusting the angle between the first light beam and the first refractive surface.

[0077] For example, refer to Figure 2, multiple first light beams can reach the target tissue after passing through the first collimating lens, the first beam combining optical element, the scanner and the objective lens in sequence.

[0078] The multi-wavelength fiber optic imaging device provided in this embodiment further includes a first beam-combining optical element having a first and a second parallel refractive surface. After being collimated by a first collimating lens, multiple first light beams with parallel propagation directions are refracted upon entering the first beam-combining optical element through the first refractive surface and further refracted upon exiting the first beam-combining optical element through the second refractive surface. Because the wavelengths of the multiple first light beams differ, the first beam-combining optical element has different refractive indices for the first light beams of different wavelengths, and the lateral displacements of the multiple first light beams also differ. This allows the propagation directions of the multiple first light beams to coincide, thereby combining the corresponding beams of the multiple first light beams and enabling the multiple first light beams of different wavelengths to image the same region of target tissue.

[0079] Figure 6 The figure shows a schematic diagram of a structure applicable to an application scenario of a second beam combining optical element provided by an embodiment of the present application. Figure 2 and Figure 6 As shown, the multi-wavelength fiber optic imaging device 10 further includes a second beam combining optical element 16 .

[0080] The second beam-combining optical element 16 is positioned between the first collimating lens 140 and the scanner 12. The second beam-combining optical element 16 includes a plurality of first optical film layers 160 arranged parallel to each other and spaced apart. The plurality of first optical film layers 160 correspond one-to-one to the plurality of first light beams 20. Each first optical film layer 160 is capable of reflecting the corresponding first light beam 20 and transmitting all first light beams 20 except the corresponding first light beam 20, so that each first light beam 20 reaches the corresponding first optical film layer 160. Furthermore, after the plurality of first light beams 20 are reflected by the corresponding first optical film layer 160, the propagation directions of the plurality of first light beams 20 overlap.

[0081] In some application scenarios, after being collimated by the first collimating lens 140, the beam directions of the multiple first light beams 20 are the same, the propagation directions of the multiple first light beams 20 are parallel and do not overlap, and the center of mass of the light spots of the multiple first light beams 20 are slightly spaced apart and do not overlap. When the multiple first light beams 20 propagate to the second beam-combining optical element 16, because the multiple first optical film layers 160 correspond one-to-one to the multiple first light beams 20, each first optical film layer 160 can reflect the corresponding first light beam 20 and transmit the first light beams 20 other than the corresponding first light beam 20, so that each first light beam 20 can reach the corresponding first optical film layer 160 and be reflected by the corresponding first optical film layer 160.

[0082] Since the multiple first optical film layers 160 are arranged in parallel and at intervals, the propagation directions of the multiple first light beams 20 are parallel. By adjusting the position of the first optical film layer 160, the lateral displacement of the first light beam 20 can be independently adjusted, so that the center of mass of the light spots corresponding to the multiple first light beams 20 coincide, and the propagation directions of the multiple first light beams 20 coincide, so as to realize the combination of the light beams corresponding to the multiple first light beams 20.

[0083] Exemplarily, when a plurality of first light beams 20 with parallel propagation directions propagate to the second beam-combining optical element 16 , the propagation direction of each first light beam 20 is neither parallel nor perpendicular to the corresponding first optical film layer 160 .

[0084] For example, the plurality of first light beams may sequentially pass through a first collimating lens, a second beam combining optical element, a scanner, and an objective lens before reaching the target tissue. For example, the plurality of first light beams may sequentially pass through a first collimating lens, a first beam combining optical element, a second beam combining optical element, a scanner, and an objective lens before reaching the target tissue.

[0085] Exemplarily, the first optical film layer may include a dichroic film. Exemplarily, the first optical film layer may also include a narrow-band reflective film. Optionally, the second beam-combining optical element may include a plurality of stacked optical glass plates, each surface of which is coated with the first optical film layer. Exemplarily, the number of optical glass plates may be the same as the number of wavelengths of the first light beam. The optical glass plates have a first plane and a second plane disposed opposite to each other. The first plane of each optical glass plate is coated with a corresponding first optical film layer.

[0086] The multi-wavelength fiber imaging device provided in this embodiment further includes a second beam-combining optical element, which includes a plurality of first optical film layers arranged parallel to each other and spaced apart, the plurality of first optical film layers corresponding one-to-one to the plurality of first light beams. Each first optical film layer is capable of reflecting the corresponding first light beam and transmitting first light beams other than the corresponding first light beam, so that each first light beam can reach the corresponding first optical film layer and be reflected by the corresponding first optical film layer, thereby aligning the centroids of the light spots corresponding to the plurality of first light beams and aligning the propagation directions of the plurality of first light beams collimated by the first collimating lens, thereby achieving beam combining of the plurality of first light beams, thereby enabling the plurality of first light beams of different wavelengths to image the same area of ​​the target tissue.

[0087] In addition, by adjusting the position of the first optical film layer, the lateral displacement of the first light beam can be independently adjusted. For complex situations such as a large number of wavelength types of the first light beam, the second beam-combining optical element can still realize the beam combining of multiple light beams corresponding to the first light beams, thereby expanding the application scenarios of the multi-wavelength fiber optic imaging device.

[0088] Figure 7The figure shows a structural diagram of an application scenario suitable for a transmission optical fiber and a second collimating lens provided by an embodiment of the present application. Figure 8 Shown is a structural schematic diagram of an application scenario of a multi-wavelength fiber optic imaging device provided by yet another embodiment of the present application.

[0089] like Figure 7 and Figure 8 As shown, the collimating optical element 14 includes a second collimating lens 141. The second collimating lens 141 is positioned between the plurality of transmission optical fibers 11 and the scanner 12 and is configured to collimate the first light beams 20 output from the second ends 111 of the plurality of transmission optical fibers. The second collimating lens 141 has a second principal optical axis L2. The rotation axis L3 of each light cone formed by the first light beam 20 emitted from the second end 111 of the transmission optical fiber can extend parallel to or coincide with the direction of the second principal optical axis L2.

[0090] Specifically, the first light beam 20 forms a light cone after being emitted from the second end 111 of the transmission optical fiber. The extension direction of the rotation axis L3 of the light cone formed by the first light beam 20 is parallel to or coincides with the second main optical axis L2.

[0091] In some implementations, the rotation axes of the light cones formed by the first light beams 20 emitted from the second ends 111 of the multiple transmission optical fibers can extend in directions parallel to the direction of the second principal optical axis L2. In other implementations, the rotation axis L3 of the light cone formed by one of the first light beams 20 emitted from the second ends 111 of the multiple transmission optical fibers can extend in directions that coincide with the direction of the second principal optical axis L2, while the rotation axes L3 of the light cones formed by the remaining first light beams 20 can extend in directions parallel to the direction of the second principal optical axis L2.

[0092] The second collimating lens 141 has a plurality of second focal points 1410 and a plurality of focal planes 1411. The plurality of second focal points 1410 correspond one-to-one to the plurality of first light beams 20, and each focal plane 1411 includes a second focal point 1410. The second end 111 of the transmission optical fiber corresponding to the first light beam 20 is located at the focal plane 1411 corresponding to the same first light beam 20.

[0093] Specifically, since the wavelengths of the multiple first light beams 20 are different, different first light beams 20 correspond to different second focal points 1410. Different second focal points 1410 are located in different focal planes 1411. The multiple focal planes 1411 are perpendicular to the second principal optical axis L2 and are arranged at intervals. Since the second end 111 of the transmission optical fiber corresponding to the first light beam 20 is located in the focal plane 1411 corresponding to the same first light beam 20, and the extension direction of the rotation axis L3 of each light cone formed by the first light beam 20 emitted by the second end 111 of the transmission optical fiber can be parallel to or coincide with the extension direction of the second principal optical axis L2, the second collimating lens 141 can achieve simultaneous collimation of the multiple first light beams 20 and compensate for the axial chromatic aberration when the multiple first light beams 20 are collimated.

[0094] Illustratively, the second end 111 of the transmission optical fiber may be an end face of the distal end of the transmission optical fiber 11. Illustratively, the extending direction of the second end 114 of the transmission optical fiber is parallel to or coincides with the extending direction of the second principal optical axis L2.

[0095] For example, Figure 8 As shown, multiple first light beams 20 can sequentially pass through the second collimating lens 141, the scanner 12, and the objective lens 13 before reaching the target tissue. In other words, the multiple first light beams collimated by the second collimating lens do not need to be combined before reaching the target tissue. This arrangement helps simplify the structure of the multi-wavelength fiber optic imaging device, reducing the size and weight of the multi-wavelength fiber optic imaging device, allowing the multi-wavelength fiber optic imaging device to meet the requirements of miniaturization and lightweighting, making the multi-wavelength fiber optic imaging device suitable for application scenarios with high requirements for size and weight.

[0096] In the multi-wavelength fiber optic imaging device provided in this embodiment, a second collimating lens serves as a collimating optical element to collimate the first light beams transmitted by multiple transmission optical fibers. Because the wavelengths of the multiple first light beams differ, different first light beams correspond to different second focal points. Because the line connecting the orthographic projection of the second end of the transmission optical fiber corresponding to the first light beam and the second focal point corresponding to the same first light beam on a plane passing through the second principal optical axis is perpendicular to the second principal optical axis, the second end of the transmission optical fiber corresponding to the first light beam is located in the focal plane corresponding to the same first light beam. Furthermore, because the rotation axis of the light cone formed by each first light beam emitted from the second end of the transmission optical fiber can extend parallel to or coincide with the extension direction of the second principal optical axis, the second collimating lens can simultaneously collimate the multiple first light beams and compensate for axial chromatic aberration during the collimation of the multiple first light beams. This avoids the need for a complex achromatic design for the multi-wavelength fiber optic imaging device, reduces the manufacturing cost, volume, and weight of the multi-wavelength fiber optic imaging device, and facilitates imaging of target tissue by the multiple first light beams collimated by the second collimating lens without combining them.

[0097] Figure 9FIG2 is a schematic diagram of a structure of an application scenario of a third beam combining optical element provided by an embodiment of the present application. Figure 2 、 Figure 8 and Figure 9 The multi-wavelength fiber imaging device 10 further includes a third beam-combining optical element 17. The third beam-combining optical element 17 is located between the second collimating lens 141 and the scanner 12. The third beam-combining optical element 17 includes a plurality of second optical film layers 170, with the normal directions of the plurality of second optical film layers 170 intersecting with each other. The plurality of second optical film layers 170 correspond one-to-one to the plurality of first light beams 20. Each second optical film layer 170 is capable of reflecting the corresponding first light beam 20 and transmitting the first light beams 20 other than the corresponding first light beam 20, so that each first light beam 20 can reach the corresponding second optical film layer 170, and after the plurality of first light beams 20 are respectively reflected by the corresponding second optical film layer 170, the propagation directions of the plurality of first light beams 20 overlap.

[0098] The working principle of the third beam combining optical element 17 is similar to that of the second beam combining optical element 16. In some application scenarios, such as Figure 9 As shown, after being collimated by the second collimating lens 150, the propagation directions of the multiple first light beams 20 intersect with each other, and the centroids of the light spots corresponding to the multiple first light beams 20 do not overlap. When the multiple first light beams 20 propagate to the third beam-combining optical element 17, since the multiple second optical film layers 170 correspond one-to-one to the multiple first light beams 20, each second optical film layer 170 can reflect the corresponding first light beam 20 and transmit the first light beams 20 other than the corresponding first light beam 20, so that each first light beam 20 can reach the corresponding second optical film layer 170 and be reflected by the corresponding second optical film layer 170.

[0099] Since the normals of the multiple second optical film layers 170 are arranged to intersect with each other, the incident angle and incident point of the first light beam 20 can be independently adjusted by adjusting the position and angle of the second optical film layer 170, so that the center of mass of the light spots corresponding to the multiple first light beams 20 coincide, and the propagation directions of the multiple first light beams 20 coincide, thereby realizing the combination of the light beams corresponding to the multiple first light beams 20.

[0100] For example, Figure 9 As shown, the plurality of second optical film layers 170 can be spaced apart. For example, adjacent second optical film layers can also be connected. For example, the second optical film layer can include a dichroic film. For example, the second optical film layer can include a narrow-band reflective film, a broadband reflective film, or a metal film.

[0101] Exemplarily, the plurality of first light beams may sequentially pass through the second collimating lens, the third beam combining optical element, the scanner, and the objective lens before reaching the target tissue.

[0102] The multi-wavelength fiber imaging device provided in this embodiment further includes a third beam-combining optical element, which includes a plurality of second optical film layers, the normal directions of the plurality of second optical film layers being arranged to intersect with each other, and the plurality of second optical film layers corresponding one-to-one to the plurality of first light beams. Each second optical film layer is capable of reflecting the corresponding first light beam and transmitting the first light beams other than the corresponding first light beam, so that each first light beam can reach the corresponding second optical film layer and be reflected by the corresponding second optical film layer, thereby aligning the centroids of the light spots corresponding to the plurality of first light beams and aligning the propagation directions of the plurality of first light beams after being collimated by the second collimating lens, thereby achieving beam combining of the plurality of first light beams, so that the plurality of first light beams of different wavelengths can image the same area of ​​the target tissue.

[0103] In addition, by adjusting the position and angle of the second optical film layer, the incident angle and incident point of the first light beam can be adjusted independently. For complex situations such as a large number of wavelength types of the first light beam, the third beam-combining optical element can still realize the beam combining of multiple light beams corresponding to the first light beams, thereby expanding the application scenarios of the multi-wavelength fiber optic imaging device.

[0104] Figure 10 FIG. 1 is a schematic diagram of the field of view of a multi-wavelength fiber optic imaging device provided in one embodiment of the present application. Figure 10 As shown, the multiple first light beams 20 have respective corresponding field of view ranges, and the field of view range 203 of the multi-wavelength fiber optic imaging device is the intersection of the respective corresponding field of view ranges of the multiple first light beams 20 .

[0105] Since the fields of view corresponding to the multiple first light beams 20 may not completely overlap, for example, when the propagation directions of the multiple first light beams incident on the objective lens intersect with each other, the intersection of the fields of view corresponding to the multiple first light beams 20 can be obtained, and the intersection can be determined as the field of view of the microdevice 10. The field of view 203 of the multi-wavelength fiber optic imaging device can be determined and calibrated to improve imaging quality.

[0106] For example, Figure 10 As shown, first light beam 20 is a red light beam, a blue light beam, or a green light beam. Three transmission optical fibers 11 transmit the red light beam, the blue light beam, and the green light beam, respectively. The red light beam has a first field of view 200, the blue light beam has a second field of view 201, and the green light beam has a third field of view 202. The field of view 203 of the multi-wavelength fiber optic imaging device can be the intersection of the first field of view 200, the second field of view 201, and the third field of view 202.

[0107] For example, Figure 8As shown, the multiple first light beams collimated by the second collimating lens do not need to be combined before reaching the target tissue. The propagation directions of the multiple first light beams intersect with each other, and the fields of view corresponding to the multiple first light beams do not completely overlap. The common portion of the fields of view corresponding to the multiple first light beams can be intercepted so that multiple first light beams of different wavelengths can reach the same area of ​​the target tissue. The same area of ​​the target tissue can then provide feedback to the multiple first light beams of different wavelengths, thereby improving the imaging quality of the target tissue.

[0108] Figure 11 FIG2 is a schematic diagram of a structure of an application scenario of a multi-wavelength fiber optic imaging system according to an embodiment of the present invention. A multi-wavelength fiber optic imaging device 10 can be applied to a multi-wavelength fiber optic imaging system 1 .

[0109] In some embodiments, as Figure 11 As shown, the multi-wavelength fiber optic imaging device 10 also includes a probe 18 having a housing 180. Housing 180 is used to accommodate the second ends 111 of the multiple transmission optical fibers, the scanner 12, and the objective lens 13. By integrating the second ends of the multiple transmission optical fibers, the scanner, and the objective lens into the probe, the probe protects the aforementioned components. Furthermore, the probe's shape and size can be designed based on actual applications, enabling the multi-wavelength fiber optic imaging device to be applied in a wide range of scenarios.

[0110] Exemplarily, the second end of the transmission optical fiber, the scanner, and the objective lens are all connected to the probe. This allows the probe to support and secure these structures. Exemplarily, the multi-wavelength fiber optic imaging device or a probe integrating the second end of the transmission optical fiber, the scanner, and the objective lens can be used as an endoscope, an in vivo clinical diagnostic tool for observing the internal cavity of animals or humans, or as a handheld or wearable multi-wavelength fiber optic imaging device.

[0111] Exemplarily, the accommodation space is also used to accommodate a collimating optical element. For example, the accommodation space can also be used to accommodate a first collimating lens, and can also be used to accommodate a second collimating lens. Exemplarily, the accommodation space can also accommodate a first collimating lens and a first beam-combining optical element, and can also be used to accommodate a first collimating lens and a second beam-combining optical element. Exemplarily, the accommodation space can also accommodate a second collimating lens and a third beam-combining optical element.

[0112] like Figure 11 As shown, an embodiment of the present application further provides a multi-wavelength fiber optic imaging system 1. The multi-wavelength fiber optic imaging system 1 comprises: the multi-wavelength fiber optic imaging device 10 described in any of the above embodiments and a plurality of light sources 40. The plurality of light sources 40 are respectively located at the first light beam receiving side 113 of the plurality of transmission optical fibers, and are configured to respectively provide first light beams 20 of different wavelengths to the first ends 110 of the plurality of transmission optical fibers.

[0113] Specifically, the first-beam receiving side of the transmission fiber 113 is a side of the transmission fiber 11 for receiving the first beam 20. Further, the first-beam receiving side of the transmission fiber 113 is a side of the first end 110 of the transmission fiber for receiving the first beam 20. Exemplarily, the light source 40 and the first beam 20 are in one-to-one correspondence. The number of the light sources 40 can be the same as the number of the wavelength categories of the first beams 20. Exemplarily, the light source can include a continuous laser, a pulsed laser, or a light-emitting diode.

[0114] Exemplarily, the multi-wavelength fiber imaging system can be a distally-scanned multi-wavelength fiber imaging system. The second end of the transmission fiber, the scanner, and the objective lens can be located at the distal end, and the first end of the transmission fiber and the light source can be located at the proximal end.

[0115] Since the multi-wavelength fiber imaging system 1 includes the multi-wavelength fiber imaging device 10, the multi-wavelength fiber imaging system 1 has all the technical features and technical effects of the multi-wavelength fiber imaging device 10, which will not be repeated here.

[0116] In some application scenarios, the multi-wavelength fiber imaging system 1 can further include a module for collecting a plurality of second beams to convert the optical signal into an electrical signal to generate an image of the target tissue. The collection of a plurality of second beams and the generation of an image of the target tissue using a plurality of second beams can be implemented using common knowledge or conventional techniques in the art, which will not be repeated here.

[0117] Figure 12 Fig. 1 shows a structure schematic diagram of an application scenario suitable for the transmission fiber and the light source according to an embodiment of the present application.

[0118] In some embodiments, as shown in Figs. 1-2, Figure 1 , Figure 11 and Figure 12 the multi-wavelength fiber imaging system 1 further includes at least one coupler 50. The at least one coupler 50 is located between the plurality of light sources 40 and the corresponding first end 110 of the transmission fiber, for coupling the first beam 20 provided by the at least one light source 40 to the corresponding first end 110 of the transmission fiber.

[0119] Exemplarily, the coupler can include a gradient-index lens, a spherical lens, an aspherical lens, a cemented lens, or a lens group. For example, the coupler can be a microscopic objective lens.

[0120] Exemplarily, as shown in Figs. 1-2, Figure 1 and Figure 11As shown, the multi-wavelength fiber-optic imaging system 1 can include multiple couplers 50. There is a one-to-one correspondence between the couplers 50, the light sources 40, and the transmission fibers 11. Each coupler 50 can be used to couple the first light beam 20 provided by the corresponding light source 40 to the first end 110 of the corresponding transmission fiber. For example, when parameters such as the mode field diameter and numerical aperture of the multiple transmission fibers vary significantly, each first light beam can be coupled to the first end of the corresponding transmission fiber by the corresponding coupler.

[0121] For example, Figure 12 As shown, the multi-wavelength fiber-optic imaging system 1 can include a coupler 50. The coupler 50 can be used to couple the first light beams 20 provided by the multiple light sources 40 to the first ends 110 of the corresponding transmission fibers. For example, when the parameters such as the mode field diameter and numerical aperture of the multiple transmission fibers differ slightly, the multiple first light beams can be coupled to the first ends of the corresponding transmission fibers by the same coupler.

[0122] In some embodiments, as Figure 12 As shown, the multi-wavelength fiber optic imaging system 1 may further include a second fiber optic ferrule 60. In each transmission optical fiber 11, the first end 110 of the transmission optical fiber may be the terminal end of the first end portion 115 of the transmission optical fiber. Multiple first end portions 115 of the transmission optical fibers may be inserted into the same second fiber optic ferrule 60. This allows for the securement of the multiple first ends 110 of the transmission optical fibers, helps reduce the overall circumferential dimensions of the multiple first end portions 115 of the transmission optical fibers, and facilitates coupling the first light beams 20 provided by the multiple light sources 40 to the corresponding first ends 110 of the transmission optical fibers using the same coupler 50.

[0123] In some embodiments, as Figure 12 As shown, the multi-wavelength fiber optic imaging system 1 may further include at least one reflector 70. Reflector 70 is located between the light source 40 and the coupler 50 and is configured to reflect the first light beam 20. By using the reflector to change the propagation direction of the first light beam provided by the light source, the angle at which the first light beam enters the coupler is adjusted. This facilitates the passage of different first light beams through the same coupler into the first ends of multiple transmission optical fibers at different locations. This allows multiple first light beams of different wavelengths to be coupled into corresponding transmission optical fibers by the same coupler, thereby improving coupling efficiency.

[0124] In some embodiments, as Figure 1 、 Figure 11 and Figure 12 As shown, the multi-wavelength fiber optic imaging system 1 may further include at least one optical modulator 80. The optical modulator 80 is located between the light source 40 and the coupler 50 and is used to control the intensity of the first light beam 20 provided by the light source 40. The optical modulator can regulate the optical power or intensity of the first light beam output by the light source to meet the optical power or intensity requirements of the first light beam for imaging the target tissue.

[0125] Exemplarily, the light source 40 corresponds to the light modulator 80. Exemplarily, the light modulator may include an electro-optic crystal modulator, an acousto-optic crystal modulator, or a liquid crystal modulator. Exemplarily, the light modulator may also include a mechanically rotatable half-wave plate and a polarization-dependent beam splitter.

[0126] For example, Figure 4 As shown, since the multiple first light beams reach the target tissue after passing through the first collimating lens, the scanner and the objective lens in sequence, that is, the multiple first light beams collimated by the first collimating lens are not combined before reaching the target tissue, after being collimated by the first collimating lens, the propagation directions of the multiple first light beams are parallel and do not overlap, and the centroids of the light spots corresponding to the multiple first light beams have a small distance between them and do not overlap.

[0127] Since the overall size of the centroid of the light spot corresponding to the multiple first light beams may be larger than the size of the entrance pupil diameter in the multi-wavelength fiber optic imaging device, at least a portion of the light beam corresponding to at least one first light beam is blocked by the aperture, resulting in a reduction in the effective optical power of the first light beam under the objective lens. In this case, the optical power or intensity of the first light beam blocked by the aperture can be increased by an optical modulator to compensate for the reduction in the effective optical power of the first light beam under the objective lens. In this way, high imaging quality of the target tissue can still be obtained without combining the multiple first light beams after being collimated by the first collimating lens before reaching the target tissue. In addition, the multi-wavelength fiber optic imaging device does not need to be provided with a beam combining optical element, and the entrance pupil diameter can also be designed to be smaller, which is conducive to reducing the volume and weight of the multi-wavelength fiber optic imaging device, so that the multi-wavelength fiber optic imaging device can be used in application scenarios with high requirements for volume and weight. For example, the multi-wavelength fiber optic imaging device can be used as an endoscope or a wearable multi-wavelength fiber optic imaging device.

[0128] In some embodiments, as Figure 11 As shown, the objective lens 13 is further configured to receive a second light beam 90 fed back from the target tissue 30 after the first light beam 20 is input into the target tissue 30, and output the second light beam 90 to the scanner 12. The scanner 12 is further configured to output the received second light beam 90 to the second end 111 of the transmission optical fiber. The first end 110 of the transmission optical fiber is also configured to output the second light beam 90.

[0129] In some embodiments, as Figure 11 As shown, the multi-wavelength fiber optic imaging system 1 may further include a second beam collection module 91. The second beam collection module 91 is located between the light source 40 and the coupler 50 and is configured to collect the second beam 90. The coupler 50 is further configured to couple the second beam 90 output from the first end 110 of the transmission optical fiber to the second beam collection module 91.

[0130] For example, Figure 11As shown, the second light beam collection module 91 may include a beam splitter 910 and a photoelectric conversion module 911. The beam splitter 910 is located between the coupler 50 and the light source 40, and is capable of transmitting the first light beam 20 and reflecting the second light beam 90. The photoelectric conversion module 911 is located on the side of the beam splitter 910 that reflects the second light beam 90, and is used to convert the received second light beam 90 into an electrical signal.

[0131] For example, the optical splitter 910 may include one or more combinations of optical elements such as a dichroic mirror, a prism, a grating, etc. For example, the photoelectric conversion module 911 may include a photodetector.

[0132] Exemplarily, the second light beam collection module 91 may further include a condenser lens 912 . The condenser lens 912 is located between the beam splitter 910 and the photoelectric conversion module 911 and is configured to converge the second light beam 90 reflected by the beam splitter 910 to the photoelectric conversion module 911 .

[0133] In some embodiments, the multi-wavelength fiber-optic imaging system 1 may further include a host 92. The host 92 may integrate the first end 110 of the transmission fiber and the light source 40. The host 92 may also integrate the coupler 50, the optical modulator 80, and the reflector 70. The host 92 may also integrate a second beam collection module 91.

[0134] For example, a system on chip (SOC) or a field programmable gate array (FPGA) may be integrated into the host to process the electrical signal provided by the photodetector.

[0135] In some embodiments, the objective lens is also used to receive multiple second light beams of different wavelengths. The multi-wavelength fiber optic imaging device may also include a dichroic mirror and an imaging fiber. The dichroic mirror is located between the objective lens and the scanner, and is capable of transmitting multiple first light beams and reflecting multiple second light beams. One end of the imaging fiber is located on the second light beam output side of the dichroic mirror, and is used to receive the multiple second light beams reflected by the dichroic mirror. The other end of the imaging fiber is used to output multiple second light beams of the dichroic paste so that the multiple second light beams can be collected. The multi-wavelength fiber optic imaging system also includes a photoelectric conversion imaging module, which is located on the second light beam output side of the imaging fiber, and is used to receive the multiple second light beams and convert the received multiple second light beams into electrical signals to generate an image of the target tissue.

[0136] The basic principles of the present application have been described above in conjunction with specific embodiments. However, it should be noted that the advantages, strengths, and effects mentioned in this application are merely illustrative and not restrictive, and it should not be assumed that these advantages, strengths, and effects are required of each embodiment of this application. In addition, the specific details disclosed above are merely illustrative and facilitating understanding, and are not restrictive. The above details do not limit this application to necessarily being implemented using the above specific details.

[0137] The block diagrams of the devices, devices, equipment, and systems involved in this application are merely illustrative examples and are not intended to require or imply that they must be connected, arranged, or configured in the manner shown in the block diagrams. As will be appreciated by those skilled in the art, these devices, devices, equipment, and systems can be connected, arranged, or configured in any manner. Words such as "include," "comprise," "have," "have," and the like are open-ended words, meaning "including but not limited to," and can be used interchangeably therewith. The words "or" and "and" used herein refer to the words "and / or" and can be used interchangeably therewith, unless the context clearly indicates otherwise. The word "such as" used herein refers to the phrase "such as but not limited to," and can be used interchangeably therewith.

[0138] It should also be noted that in the apparatus, device, and method of the present application, each component or each step can be decomposed and / or recombined, and such decomposition and / or recombination should be regarded as equivalent solutions of the present application.

[0139] The above description of the disclosed aspects is provided to enable any person skilled in the art to make or use the present application. Various modifications to these aspects will be readily apparent to those skilled in the art, and the general principles defined herein may be applied to other aspects without departing from the scope of the present application. Therefore, the present application is not intended to be limited to the aspects shown herein, but rather to be accorded the widest scope consistent with the principles and novel features disclosed herein.

[0140] The above description has been provided for the purpose of illustration and description. In addition, this description is not intended to limit the embodiments of the present application to the forms disclosed herein. Although a number of example aspects and embodiments have been discussed above, those skilled in the art will recognize certain variations, modifications, alterations, additions, and sub-combinations thereof.

Claims

1. A multi-wavelength optical fiber imaging device, characterized in that: include: a plurality of transmission optical fibers, each of the plurality of transmission optical fibers being used to transmit a plurality of first light beams, each of the first light beams transmitted by the transmission optical fibers having a different wavelength, a first end of the transmission optical fiber being used to receive the first light beam, and a second end of the transmission optical fiber being used to output the first light beam; a scanner, located at the first light beam output side of the plurality of transmission optical fibers, configured to receive the first light beams transmitted from the second ends of the plurality of transmission optical fibers, and change propagation directions of the plurality of first light beams to scan a target tissue using the plurality of first light beams; The objective lens is located at the first light beam output side of the scanner, and is used to focus the plurality of first light beams on the target tissue to image the target tissue.

2. The multi-wavelength optical fiber imaging device according to claim 1, characterized in that: Also includes: A collimating optical element is located between the plurality of transmission optical fibers and the scanner, and is used to collimate the first light beams output from the second ends of the plurality of transmission optical fibers.

3. The multi-wavelength optical fiber imaging device according to claim 2, characterized in that: The collimating optical element includes a first collimating lens, which is located between the plurality of transmission optical fibers and the scanner and is used to collimate the first light beams output from the second ends of the plurality of transmission optical fibers; In which, the first collimating lens has multiple first focal points located on the first principal optical axis, the multiple first focal points respectively correspond to multiple first light beams, and the second end of the transmission optical fiber corresponding to the first light beam is located at the first focal point corresponding to the same first light beam, so that the propagation directions of the multiple first light beams emitted by the first collimating lens are parallel.

4. The multi-wavelength optical fiber imaging device according to claim 3, characterized in that: The first collimating lens includes a lens and / or a lens group having an Abbe number smaller than a preset value, so as to increase the distance between adjacent first focal points.

5. The multi-wavelength optical fiber imaging device according to claim 3, characterized in that: Also includes: A first beam-combining optical element is located between the first collimating lens and the scanner. The first beam-combining optical element has a first refractive surface and a second refractive surface that are parallel to each other. When multiple first light beams with parallel propagation directions propagate to the first refractive surface, the incident angle of the first light beam is greater than 0° and less than 90°. The multiple first light beams can enter the first beam-combining optical element through the first refractive surface and exit the first beam-combining optical element through the second refractive surface. After the multiple first light beams are emitted from the second refractive surface, the propagation directions of the multiple first light beams coincide.

6. The multi-wavelength optical fiber imaging device according to claim 3, characterized in that: Also includes: The second beam-combining optical element is located between the first collimating lens and the scanner. The second beam-combining optical element includes a plurality of first optical film layers that are parallel to each other and spaced apart. The plurality of first optical film layers correspond one-to-one to the plurality of first light beams. Each first optical film layer can reflect the corresponding first light beam and transmit the first light beams other than the corresponding first light beam, so that each first light beam can reach the corresponding first optical film layer, and after the plurality of first light beams are respectively reflected by the corresponding first optical film layers, the propagation directions of the plurality of first light beams coincide.

7. The multi-wavelength optical fiber imaging device according to claim 2, characterized in that: The collimating optical element includes a second collimating lens, which is located between the plurality of transmission optical fibers and the scanner and is used to collimate the first light beams output from the second ends of the plurality of transmission optical fibers, and the second collimating lens has a second principal optical axis; wherein the extension direction of the rotation axis of each light cone formed by the first light beam emitted from the second end of the transmission optical fiber can be parallel to or coincide with the extension direction of the second main optical axis; The second collimating lens has multiple second focal points and multiple focal planes. The multiple second focal points correspond one-to-one to the multiple first light beams. Each focal plane contains one second focal point. The second end of the transmission optical fiber corresponding to the first light beam is located on the focal plane corresponding to the same first light beam.

8. The multi-wavelength optical fiber imaging device according to claim 7, characterized in that: Also includes: A third beam-combining optical element is located between the second collimating lens and the scanner. The third beam-combining optical element includes multiple second optical film layers. The normals of the multiple second optical film layers are arranged to cross each other. The multiple second optical film layers correspond one-to-one to the multiple first light beams. Each second optical film layer can reflect the corresponding first light beam and transmit the first light beams except the corresponding first light beam, so that each first light beam can reach the corresponding second optical film layer, and after the multiple first light beams are respectively reflected by the corresponding second optical film layers, the propagation directions of the multiple first light beams coincide.

9. The multi-wavelength optical fiber imaging device according to claim 7, characterized in that: The plurality of first light beams have respective corresponding fields of view, and the field of view of the multi-wavelength fiber optic imaging device is the intersection of the respective fields of view corresponding to the plurality of first light beams.

10. The multi-wavelength optical fiber imaging device according to any one of claims 1 to 9, characterized in that: Also includes: The probe has a receiving space for receiving the second ends of the plurality of transmission optical fibers, the scanner and the objective lens.

11. A multi-wavelength fiber optic imaging system, characterized in that: include: The multi-wavelength optical fiber imaging device according to any one of claims 1 to 10; A plurality of light sources are respectively located at the first light beam receiving sides of the plurality of transmission optical fibers, and are used to respectively provide the first light beams with different wavelengths to the first ends of the plurality of transmission optical fibers.

12. The multi-wavelength fiber optic imaging system according to claim 11, characterized in that: Also includes: At least one coupler is located between the plurality of light sources and the first ends of the corresponding transmission optical fibers, and is used to couple the first light beam provided by at least one of the light sources to the first ends of the corresponding transmission optical fibers.

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