Intelligent feeding device for medical experiment mice and feeding method

Abstract

The invention provides an intelligent food intake device for medical experiment mice and a feeding method thereof. The intelligent food intake device comprises a food storage device, a food discharging mechanism, a food trough, a nose poking mechanism and a data processor. The grain outlet mechanism comprises a grain outlet part and a driving device, the grain storage device is used for storing food, a grain outlet is formed between the grain storage device and the trough, a grain outlet part is arranged at the grain outlet, the driving device is connected with and drives the grain outlet part to open or close the grain outlet, and the grain outlet part is driven to open the grain outlet, so that the food in the grain storage device is quantitatively brought to the grain outlet, and the food falls into the trough from the grain outlet. The grain outlet piece is driven to close the grain outlet, and the grain outlet stops discharging grain; a first sensor is arranged on the feeding trough; the nose pricking mechanism comprises at least two nose pricking holes, the nose pricking holes are formed in the two sides of the feeding trough, and sensors are arranged on the nose pricking holes respectively; the data processor is in communication connection with the first sensor, the second sensor, the third sensor and the driving device, and the data processor is provided with a charging and data transmission interface or a wireless data transmission module. The scheme is used for researching the ingestion behavior of mice.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of feeding device, and in particular to a medical experimental mouse intelligent feeding device and a feeding method. BACKGROUND

[0002] Experimental mice are widely used in behavioral science, neuroscience, metabolic disease and other fields as model organisms. The current mainstream experimental mouse feeding device is limited to daily feeding scenarios, and its main functions include basic feeding, reducing food waste or maintaining a clean feeding environment, which cannot meet the high-precision needs of scientific research. Specifically, first, it cannot accurately record the amount and time of food intake, relying mainly on manual observation or rough weighing, which cannot achieve milligram-level food intake and second-level food intake time, and cannot support the analysis of subtle behavioral differences in behavioral experiments; second, it lacks intelligent incentive control, only having passive feeding function, which cannot quantify key behavioral indicators such as mouse learning ability and motivation strength; third, it lacks data interaction capability, cannot be directly connected to a computer, and experimental personnel need to manually record data, which is low in efficiency and easy to introduce errors, and cannot realize real-time storage and analysis.

[0003] Therefore, the present application provides a medical experimental mouse intelligent feeding device and a feeding method to solve the above problems. SUMMARY

[0004] The present application aims to provide a medical experimental mouse intelligent feeding device and a feeding method, which can accurately quantify the amount and time of feeding, stimulate mice to eat, accurately record and export mouse feeding data, and facilitate experimental personnel to analyze.

[0005] To achieve the above purpose, the solution of the present application is a medical experimental mouse intelligent feeding device, which comprises a grain storage device, a grain outlet mechanism, a feeding trough, a nose poking mechanism and a data processor.

[0006] The grain outlet mechanism comprises a grain outlet piece and a driving device. The grain storage device is used for storing food. A grain outlet is provided between the grain storage device and the feeding trough. The grain outlet piece is provided at the grain outlet. The driving device is connected to and drives the grain outlet piece to open or close the grain outlet. The grain outlet piece is driven to open the grain outlet, so that the food in the grain storage device is quantitatively brought to the grain outlet. The food falls into the feeding trough from the grain outlet. The grain outlet piece is driven to close the grain outlet, and the grain outlet stops discharging.

[0007] A first sensor is provided on the feeding trough.

[0008] The nose poking mechanism comprises at least two nose poking holes. The nose poking holes are provided on both sides of the feeding trough. A second sensor is provided on the left nose poking hole, and a third sensor is provided on the right nose poking hole.

[0009] The data processor is in communication connection with the first sensor, the second sensor, the third sensor and the driving device, the data processor collects sensing data of the first sensor, the second sensor and the third sensor, the data processor is provided with a charging and data transmission interface and a wireless data transmission module, a computer is connected to the charging and data transmission interface of the data processor through a data line, and then data is inputted or data is downloaded through the data line, or the computer is in communication connection with the wireless data transmission module of the data processor, and then data is inputted or data is downloaded.

[0010] Further, the grain discharging mechanism further comprises a grain guiding channel, and the grain discharging member is in a rotary disc structure; the bottom of the grain storage device is provided with the grain discharging member in a slanting manner; the driving device is connected to and drives the grain discharging member to rotate to open or close the grain discharging opening; the grain discharging opening is connected to one end of the grain guiding channel; the other end of the grain guiding channel is connected to the feeding trough; the grain discharging member is rotated to open the grain discharging opening, so that the food in the grain storage device is quantitatively brought to the grain discharging opening; the food falls into the grain guiding channel from the grain discharging opening; the food falls into the feeding trough through the grain guiding channel; the grain discharging member is rotated to close the grain discharging opening, and the grain discharging opening stops discharging.

[0011] Further, the grain discharging member further comprises at least one reinforcing rib.

[0012] Further, the grain discharging mechanism further comprises a display screen in communication connection with the data processor, and the display screen is used to display the input data, the sensing data of the first sensor, the sensing data of the second sensor and the sensing data of the third sensor.

[0013] Further, the grain discharging mechanism further comprises an indicating mechanism in communication connection with the first sensor, and the indicating mechanism responds to the sensing data of the first sensor.

[0014] Further, the indicating mechanism comprises an indicating lamp, a buzzer and an external plug-in interface, the external plug-in interface is used to connect external equipment, and the indicating lamp, the buzzer and the external plug-in interface are in communication connection with the first sensor and respond to the sensing data of the first sensor.

[0015] Further, the grain discharging mechanism is arranged in a housing, and the grain discharging mechanism is in communication with the feeding trough arranged outside the housing through the grain guiding channel.

[0016] Further, the first sensor is an optical sensor, the second sensor is an optical sensor or a pressure sensor, and the third sensor is an optical sensor.

[0017] A feeding method of medical experimental mice, comprising the following steps:

[0018] S1: an operator adds food into the grain storage device;

[0019] S2: The operator inputs data through the charging and data transmission interface or the wireless data transmission module, and the input data includes three modes: free feeding mode, timed feeding mode, fixed nose poking feeding mode and gradual nose poking feeding mode;

[0020] The parameters of the free feeding mode include: total experimental duration, upper limit of daily food supply, and food supply time interval;

[0021] The parameters of the timed feeding mode include: total experimental duration, upper limit of daily food supply, food supply time period, and food supply quantity in each time period;

[0022] The parameters of the fixed nose poking feeding mode include: total experimental duration, upper limit of daily food supply, number of reward nose pokes, and food supply quantity;

[0023] The parameters of the gradual nose poking feeding mode include: total experimental duration, upper limit of daily food supply, and food supply quantity, and the number of nose pokes in the gradual feeding mode is calculated by the formula: ratio n+1 = ratio n + round((5 * exp(0.2 * PelletCount)) - 5), where PelletCount is the total amount of reward food, ratio n is the number of nose pokes in the nth time, ratio n+1 is the number of nose pokes in the (n+1)th time, the initial ratio1 = 1, exp() is the exponential function, and round() is the rounding function;

[0024] S3: The data processor receives the input data of the operator, processes the input data, the sensing data of the first sensor, the sensing data of the second sensor, and the sensing data of the third sensor, and then controls the driving device to open the grain outlet to feed the mice or close the grain outlet to stop feeding the mice.

[0025] The above scheme has the following advantages:

[0026] 1. Precise recording of food intake and time, accurate control of grain output by the data processor, precise control of the food intake of the mice, and precise recording of the feeding behavior of the mice by the first sensor, the second sensor, and the third sensor;

[0027] 2. Motivation and control of mice, quantification of key behavioral indicators such as learning ability and motivation intensity of mice by the nose poking mechanism and the data processor;

[0028] 3. Interactive experimental data, input data through the charging and data transmission interface or the wireless data transmission module, download sensing data, and the operator can better set the required experimental conditions and analyze the corresponding experimental results, realizing intelligent experimental operation. BRIEF DESCRIPTION OF DRAWINGS

[0029] Figure 1 Structure diagram of an embodiment of the present application;

[0030] Figure 2 Structure diagram of part of an embodiment of the present application;

[0031] Figure 3 Structure diagram of part of an embodiment of the present application;

[0032] Figure 4 Structure diagram of part of an embodiment of the present application;

[0033] Figure 5 Structure diagram of a cross section of an embodiment of the present application.

[0034] Explanation of reference numerals:

[0035] 1. A grain outlet mechanism; 11. A grain outlet; 111. A reinforcing rib; 12. A driving device; 13. A grain outlet; 14. A grain guide channel;

[0036] 2. A grain storage device; 3. A feeding trough; 31. A first sensor;

[0037] 4. A nose poking mechanism; 41. A nose poking hole; 42. A second sensor; 43. A third sensor;

[0038] 5. A data processor; 51. A charging and data transmission interface;

[0039] 6. A display screen;

[0040] 7. A housing;

[0041] 8. Food. DETAILED DESCRIPTION

[0042] The present application will be described in detail below with reference to the accompanying drawings and specific embodiments.

[0043] It should be noted that the terms “first”, “second”, etc. are only used for the purpose of description and should not be understood as indicating or implying relative importance.

[0044] The present application provides a medical experimental mouse intelligent feeder, comprising a grain storage device 2, a grain outlet mechanism 1, a feeding trough 3, a nose poking mechanism 4, and a data processor 5.

[0045] The grain outlet mechanism 1 comprises a grain outlet member 11 and a driving device 12, the food storage device 2 is used for storing food 8, a grain outlet 13 is arranged between the food storage device 22 and the food trough 3, the grain outlet member 11 is arranged at the grain outlet 13, the driving device 12 is connected with and drives the grain outlet member 11 to open or close the grain outlet 13, the grain outlet member 11 is driven to open the grain outlet 13, so that the food 8 in the food storage device 2 is quantitatively taken to the grain outlet 13, the food 8 falls into the food trough 3 from the grain outlet 13, the grain outlet member 11 is driven to close the grain outlet 13, and the grain outlet 13 stops the grain outlet.

[0046] The first sensor 31 is arranged on the food trough 3, the first sensor 31 can be an optical sensor, and the first sensor 31 is used for sensing the time when the food 8 falls into the food trough 3, the behavior of taking away the food 8 by the mouse and the time of taking away the food 8, and the information sensed by the first sensor 31 forms sensing data.

[0047] The nose poking mechanism 4 comprises at least two nose poking holes 41, the nose poking holes 41 are arranged on both sides of the food trough 3, the second sensor 42 is arranged on the left nose poking hole 41, and the third sensor 43 is arranged on the right nose poking hole 41. The nose poking mechanism 4 is used for supporting the operation of a “behavior-reward” mechanism for feeding of a mouse, which is an important tool in researches on behavior, neuroscience and metabolic diseases, especially in researches in the fields of learning and memory, feeding regulation, neural circuit, drug screening and the like. The core value of the mechanism lies in that abstract concepts such as motivation, cognition and emotion are converted into observable and quantifiable behavior indexes, and a standardized and repeatable key experimental method is provided for life science research.

[0048] The data processor 5 is in communication connection with the first sensor 31, the second sensor 42, the third sensor 43 and the driving device 12, the data processor 5 collects the sensing data of the first sensor 31, the second sensor 42 and the third sensor 43, the data processor 5 is provided with a charging and data transmission interface 51 and a wireless data transmission module. The data processor 5 controls the driving device 12, so that the driving device 12 drives the grain outlet member 11 to an accuracy of milligrams.

[0049] A feeding method of a medical experimental mouse, an operator can input data and download sensing data through the charging and data transmission interface 51 or the wireless data transmission module. The input data includes three modes: a free feeding mode, a timed feeding mode and a nose poking feeding mode.

[0050] The parameters of the free feeding mode include: a total experimental duration, an upper limit of a daily food 8 supply amount, and a food 8 supply time interval;

[0051] The parameters of the timed feeding mode include: a total experimental duration, an upper limit of a daily food 8 supply amount, a food 8 supply time period, and a food 8 supply amount in each time period;

[0052] The parameters of the fixed nose-poking feeding mode include: total experimental duration, upper limit of daily food supply, number of nose pokes for each reward, and number of food pellets for each reward.

[0053] The parameters of the gradual nose-poking feeding mode include: total experimental duration, upper limit of daily food supply, and number of food pellets for each reward. The number of nose pokes for each reward is calculated according to the formula: ratio = ratio + round((5*exp(0.2*PelletCount))-5), where PelletCount is the total number of food pellets for each reward, and radio is the number of nose pokes. The initial ratio is 1.

[0054] The data processor 5 controls the driving device 12 according to the input data of the operator, thereby controlling the food supply and achieving the feeding of mice in the three modes described above.

[0055] For example, when the operator's experiment requires the use of the fixed feeding mode to feed mice, the operator inputs the parameters of the fixed feeding mode into the computer program, including a total experimental duration of 7 days, an upper limit of daily food supply of 4g, 1g of food supply at 8:00 every day, 2g of food supply at 13:00 every day, and 1g of food supply at 17:00 every day. The above parameters of the fixed feeding mode are transmitted to the data processor 5 through the charging and data transmission interface 51 or the wireless data transmission module. Therefore, within 7 days, the data processor 5 controls the driving device 12 to drive the food outlet 11 to open the food outlet 1g at 8:00 every day, to open the food outlet 2g at 13:00 every day, and to open the food outlet 1g at 17:00 every day. When the food is dispensed, the food 8 falls into the food trough 3, the first sensor 31 senses the time of food 8 dispensing, and the data processor 5 collects and stores the time data of food 8 dispensing. The mouse starts the feeding behavior, the mouse touches the nose-poking mechanism 4 with the nose, the second sensor 42 or the third sensor 43 senses the nose-poking behavior of the mouse, and the data processor 5 collects and stores the nose-poking behavior and time data of the mouse. The mouse takes food from the food trough 3, the first sensor 31 senses the feeding behavior of the mouse, and the data processor 5 collects and stores the feeding behavior and time data of the mouse.

[0056] The nose-poking feeding mode studies the more complex behavior logic of mice through the "behavior-reward" mechanism. The nose-poking feeding mode is divided into fixed and gradual modes.

[0057] For example, when the experiment of the operator needs to feed the mouse with the fixed nose-poking feeding mode, the operator inputs the parameters of the fixed nose-poking feeding mode into the computer program, the total experimental duration is 7 days, the upper limit of the daily food supply 8 is 50, the number of nose-poking times for each reward is 2, and the number of food 8 for each reward is 5. The above parameters of the fixed nose-poking feeding mode are transmitted to the data processor 5 through the charging and data transmission interface 51 or the wireless data transmission module, then the mouse nose 2 times the nose-poking hole 41, the second sensor 42 or the third sensor 43 senses the nose-poking behavior of the mouse, the data processor 5 collects and stores the nose-poking behavior and time data of the mouse, and the data processor 5 controls the driving device 12 to drive the grain piece 11 to open and then drive 5 grains to be discharged, and then the grain piece 11 is closed. The first sensor 31 senses the food 8 delivery time, the data processor 5 collects and stores the food 8 delivery time data, the mouse goes to the food trough 3 to eat, the first sensor 31 senses the mouse eating behavior, the data processor 5 collects and stores the eating behavior and time data.

[0058] For example, when the operator inputs the parameters of the gradual nose poking feeding mode on the computer program, the total experimental duration is 7 days, the upper limit of the daily food supply is 50 pellets, and the number of food pellets rewarded each time is 1. According to the nose poking frequency formula, the first time: PelletCount = 1, the initial ratio = 1, i.e. the first nose poking is 1 time and 1 pellet is dispensed; the second time: PelletCount = 2, ratio = 1 + round(5 x exp(0.2 x 2) - 5) = 2, i.e. the second nose poking is 2 times and 1 pellet is dispensed; the third time: PelletCount = 3, ratio = 2 + round(5 x exp(0.2 x 3) - 5) = 4, i.e. the third nose poking is 4 times and 1 pellet is dispensed, and so on. The above parameters of the gradual nose poking feeding mode are transmitted to the data processor 5 through the charging and data transmission interface 51 or the wireless data transmission module. Thus, the first mouse pokes the nose poking hole 41 once, the second sensor 42 or the third sensor 43 senses the nose poking behavior of the mouse, the data processor 5 collects and stores the nose poking behavior and time data of the mouse, the data processor 5 controls the driving device 12 to drive the pellet dispensing member 11 to open and dispense 1 pellet, and then the pellet dispensing member 11 is closed. The second mouse pokes the nose poking hole 41 twice, the second sensor 42 or the third sensor 43 senses the nose poking behavior of the mouse, the data processor 5 collects and stores the nose poking behavior and time data of the mouse, the data processor 5 controls the driving device 12 to drive the pellet dispensing member 11 to open and dispense 1 pellet, and then the pellet dispensing member 11 is closed. The third mouse pokes the nose poking hole 41 four times, the second sensor 42 or the third sensor 43 senses the nose poking behavior of the mouse, the data processor 5 collects and stores the nose poking behavior and time data of the mouse, the data processor 5 controls the driving device 12 to drive the pellet dispensing member 11 to open and dispense 1 pellet, and then the pellet dispensing member 11 is closed. The first sensor 31 senses the food 8 dispensing time, the data processor 5 collects and stores the food 8 dispensing time data, the mouse takes food from the food trough 3, the first sensor 31 senses the feeding behavior of the mouse, and the data processor 5 collects and stores the feeding behavior and time data.

[0059] Finally, the operator can download the data including the food 8 dispensing time data, the nose poking behavior data, the nose poking behavior time data, the feeding behavior data, and the feeding time data through the charging and data transmission interface 51 or the wireless data transmission module. The operator can analyze the mouse behavior according to the downloaded data to support the experimental research.

[0060] As shown in the embodiments of Figure 2 and Figure 3 , the pellet dispensing mechanism 1 further comprises a pellet guiding channel 14, the pellet dispensing member 11 is in the form of a rotating disc, the bottom of the pellet storage device 2 is inclined to the pellet dispensing member 11, the driving device 12 is connected to and drives the pellet dispensing member 11 to rotate to open or close the pellet dispensing opening 13, the pellet dispensing opening 13 is connected to one end of the pellet guiding channel 14, and the other end of the pellet guiding channel 14 is connected to the food trough 3. Figure 3The shown grain process, a food 8 is stuck in the closed grain outlet 13, the grain outlet 11 drives a food 8 to rotate, when the grain outlet 13 rotates to the open position, a food 8 falls into the grain guide channel 14 from the open grain outlet 13, the food 8 falls into the food trough 3 through the grain guide channel 14, the grain outlet 13 discharges one food 8 at a time, the data processor 5 controls the rotation angle of the grain outlet 11 to accurately control the discharge amount, so that the discharge accuracy reaches the milligram level, when the food 8 in the food trough 3 reaches the discharge amount, the driving device 12 stops driving, and the grain outlet 13 stops discharging.

[0061] The grain outlet 11 also includes at least one reinforcing rib 111, which is used to increase the strength of the grain outlet 11.

[0062] In order to further study the nose poking behavior of mice, the nose poking mechanism 4 includes at least two nose poking holes 41, which are symmetrically arranged on both sides of the food trough 3, the second sensor 42 of the nose poking hole 41 on the left side of the food trough 3 senses the left nose poking behavior and time data, and the third sensor 43 of the nose poking hole 41 on the right side of the food trough 3 senses the right nose poking behavior and time data. The operator can set multiple nose poking holes 41 according to the research needs to study the mouse behavior.

[0063] The intelligent feeder also includes a display screen 6, which is in communication connection with the data processor 5, and the display screen 6 is used to display the input data, the sensing data of the first sensor 31, the sensing data of the second sensor 42 and the sensing data of the third sensor 43. The operator can view the mode of feeding mice, the parameters of the mode of feeding mice, the food 8 issuing time, the mouse feeding time, the mouse feeding quantity, the mouse nose poking behavior quantity and the mouse nose poking behavior time through the display screen 6.

[0064] The intelligent feeder also includes an indication mechanism, which is in communication connection with the first sensor 31, and the indication mechanism responds to the sensing data of the first sensor 31. After the food 8 is issued, the indication mechanism sends a prompt signal to remind the operator to observe the mouse behavior at this time or to remind the mouse to feed.

[0065] The indication mechanism plays a prompting role, and here an embodiment is given, the indication mechanism includes an indicator light, a buzzer and an external socket, the external socket is used to connect external equipment, the indicator light, the buzzer and the external socket are in communication connection with the first sensor 31, and the indicator light, the buzzer and the external socket respond to the sensing information of the first sensor 31. After the food 8 is issued, the indicator light is lit, the buzzer emits a sound, and the external socket outputs an electric signal.

[0066] The intelligent feeder also includes a housing 7, and the grain outlet mechanism 1 is arranged in the housing 7, and the grain outlet mechanism 1 is in communication with the food trough 3 arranged outside the housing 7 through the grain guide channel 14. The housing 7 protects the mechanical structure and avoids mechanical damage caused by accidental touch of personnel.

[0067] The second sensor 42 and the third sensor 43 are used to sense the number and time of the nose-poking behavior of the mouse, wherein the second sensor 42 is preferably a pressure sensor or a photoelectric sensor, and the third sensor 43 is a photoelectric sensor.

[0068] The food container is provided with a screw cap, which is used for the operator to screw the screw cap to add food 8 to the food container, and also prevents the food 8 from being damp and contaminated.

[0069] The above description is only the preferred embodiment of the present application, and is not a limitation on the design of the present application. Any equivalent changes made according to the key design of the present application shall fall within the scope of protection of the present application.

Claims

1. An intelligent feeding device for medical experimental mice, characterized by: It includes a grain storage device, a grain dispensing mechanism, a feeding trough, a nose-poking mechanism and a data processor; The grain discharging mechanism includes a grain discharging member and a driving device. The grain storage device is used to store food. A grain discharging port is provided between the grain storage device and the food trough. The grain discharging member is provided at the grain discharging port. The driving device is connected to and drives the grain discharging member to open or close the grain discharging port. The grain discharging member is driven to open the grain discharging port, so that a certain amount of food in the grain storage device is brought to the grain discharging port. The food falls from the grain discharging port into the food trough. The grain discharging member is driven to close the grain discharging port, and the grain discharging port stops discharging food. A first sensor is provided on the feeding trough; The nose-poking mechanism includes at least two nose-poking holes, which are arranged on both sides of the feeding trough, the left nose-poking hole is provided with a second sensor, and the right nose-poking hole is provided with a third sensor; The data processor is communicatively connected with the first sensor, the second sensor, the third sensor and the driving device, and collects sensing data from the first sensor, the second sensor and the third sensor. The data processor is provided with a charging and data transmission interface and a wireless data transmission module.

2. The intelligent feeding device for medical experimental mice according to claim 1, characterized in that: The grain discharging mechanism also includes a grain guiding channel. The grain discharging part is a turntable structure. The grain discharging part is tiltedly arranged at the bottom of the grain storage device. The driving device is connected to and drives the grain discharging part to rotate to open or close the grain discharging port. The grain discharging port is connected to one end of the grain guiding channel, and the other end of the grain guiding channel is connected to the food trough. The grain discharging part rotates to open the grain discharging port, so that the food in the grain storage device is brought to the grain discharging port in a fixed amount. The food falls from the grain discharging port into the grain guiding channel, and the food falls into the food trough through the grain guiding channel. The grain discharging part rotates to close the grain discharging port, and the grain discharging port stops discharging grain.

3. The intelligent feeding device for medical experimental mice according to claim 2, characterized in that: The grain discharging member further includes at least one reinforcing rib.

4. The intelligent feeding device for medical experimental mice according to claim 1, wherein: It also includes a display screen, which is communicatively connected to the data processor and is used to display input data, sensing data from the first sensor, sensing data from the second sensor, and sensing data from the third sensor.

5. The intelligent feeding device for medical experimental mice according to claim 1, characterized in that: The device also includes an indicating mechanism, which is communicatively connected to the first sensor and responds according to the sensing data of the first sensor.

6. The intelligent feeding device for medical experimental mice according to claim 5, characterized in that: The indicating mechanism includes an indicator light, a buzzer and an external socket. The external socket is used to connect to an external device. The indicator light, the buzzer and the external socket are communicatively connected to the first sensor. The indicator light, the buzzer and the external socket respond according to the sensing information of the first sensor.

7. The intelligent feeding device for medical experimental mice according to claim 1, characterized in that: The food discharging device further comprises a shell, wherein a grain discharging mechanism is arranged in the shell, and the grain discharging mechanism is communicated with a food trough arranged outside the shell through a grain guiding channel.

8. The intelligent feeding device for medical experimental mice according to claim 1, characterized in that: The first sensor is a photoelectric sensor, the second sensor is a photoelectric sensor or a pressure sensor, and the third sensor is a photoelectric sensor.

9. A method for raising mice for medical experiments, characterized by: Using the intelligent feeding device for medical experimental mice according to any one of claims 1 to 8 comprises the following steps: S1: The operator adds food to the grain storage container; S2: The operator inputs data through the charging and data transmission interface or the wireless data transmission module. The input data includes three modes: free feeding mode, timed feeding mode, fixed nose-poke feeding mode, and progressive nose-poke feeding mode; The parameters of the free-feeding model include: total experimental duration, upper limit of daily food supply, and time interval between food supply; The parameters of the timed feeding mode include: total experimental duration, upper limit of daily food supply, food supply time period, and food supply quantity in each time period; The parameters of the fixed nose-poke feeding mode included: total experimental duration, upper limit of food quantity supplied per day, number of nose-pokes rewarded per session, and amount of food rewarded per session; The parameters of the progressive nose-poke feeding model include: total experimental duration, upper limit of daily food supply, and amount of food rewarded each time. The formula for the number of nose-pokes in the progressive feeding model is: ratio n+1 =ratio n +round(5*exp(0.2*PelletCount)-5), PelletCount is the total amount of reward food, ratio n is the number of nose pokes for the nth time, ratio n+1 is the number of nose pokes (n+1), with the initial ratio1 = 1, exp() being the exponential function, and round() being the rounding function; S3: The data processor receives the input data from the operator, processes the input data, the sensing data of the first sensor, the sensing data of the second sensor and the sensing data of the third sensor, and then controls the driving device to open the food outlet to feed the mice, or close the food outlet to stop feeding the mice.

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