Vaccine atomization device

Abstract

The invention provides a vaccine atomization device, and relates to the technical field of vaccine injection. The vaccine atomization device comprises an operation table, a driving part, an injector and an atomization head. The driving part is installed on the operation table, the injector comprises a tube body and a push rod, and the tube body is used for containing vaccines and provided with a tube opening. And one end of the push rod is connected with the driving piece. The push rod is driven by the driving part to move relative to the tube body, so that the vaccine is pushed out of the tube opening. The atomizing head is detachably connected with the pipe opening, can enter the nasal cavity and is used for atomizing vaccines. According to the technical scheme, the push rod is pushed through the driving piece, automatic pushing of vaccines is achieved, the vaccine administration efficiency can be improved, and labor is saved when the device is used by medical staff.

Description

Technical Field

[0001] This invention relates to the field of vaccine injection technology, and in particular to a vaccine atomization device. Background Technology

[0002] Generally, vaccines are administered via injection or inhalation. Injection is most commonly administered via intramuscular or subcutaneous injection. This method is used for most inactivated and recombinant protein vaccines, which stimulate a systemic immune response through blood circulation. Inhalation involves nebulizing the vaccine through the nasal cavity, acting directly on the respiratory mucosa. This mimics the natural infection pathway of the virus and can simultaneously stimulate mucosal and systemic immunity. The administration time for inhaled vaccines is generally longer than that for injectable vaccines.

[0003] In existing technologies, vaccine delivery devices all use syringes, replacing the needle with an nebulizer head. Administration is done by holding the syringe by hand. Medical staff need to use one hand to hold the recipient's nose and the other hand to apply force to the plunger, which is strenuous and inefficient. Furthermore, if hundreds of people need to be vaccinated daily, it places a significant physical and mental strain on medical staff. Therefore, there is an urgent need to design a vaccine nebulizer that improves injection efficiency and reduces labor intensity. Summary of the Invention

[0004] One object of the present invention is to provide a vaccine nebulization device that solves the technical problems of low efficiency and laboriousness of inhalation-based drug delivery in the prior art.

[0005] In particular, the present invention provides a vaccine nebulizer, comprising: Control panel; The driving component is mounted on the operating table; A syringe includes a tube body and a plunger, the tube body being used to contain a vaccine and having an opening, a portion of the plunger being located within the tube body and one end being connected to a drive member, the plunger being configured to move relative to the tube body under the drive of the drive member, thereby ejecting the vaccine from the opening; The nebulizer head is detachably connected to the tube opening. The nebulizer head can enter the nasal cavity and is used to nebulize the vaccine.

[0006] Optionally, it also includes: A guide rail is mounted on the operating table, and the drive component is slidably connected to the guide rail.

[0007] Optionally, the atomizing head includes an atomizing chip, which has a first flow channel and a second flow channel. The outlets of the first flow channel and the second flow channel are arranged opposite to each other, such that the vaccine flowing out of the first flow channel collides with the vaccine flowing out of the second flow channel, thereby achieving atomization.

[0008] Optionally, the dimensions of both the first flow channel and the second flow channel are in the micrometer range.

[0009] Optionally, the atomizing head also includes a nasal inhaler, which is hemispherical in shape.

[0010] Optionally, it also includes: The conduit is connected at one end to the tube opening and at the other end to the atomizing head.

[0011] Optionally, it also includes: The Luer connector is connected to both the nozzle and the atomizing head.

[0012] Optionally, it also includes: A controller, connected to the drive unit, is used to control the operation of the drive unit.

[0013] Optionally, the control panel is provided with an atomization button, a propulsion button, and a reset button, all of which are connected to the controller; When the push button is activated, the controller controls the drive unit to move the push rod to push the vaccine out of the tube; When the nebulization button is activated, the controller controls the nebulization head to work, thereby nebulizing the vaccine; When the reset button is activated, the controller controls the drive unit to reset the push rod.

[0014] Optionally, the operating table is equipped with a display screen, which is used to display information such as whether the vaccine has been dispensed and whether it has been nebulized.

[0015] The vaccine nebulization device of this invention includes an operating table, a driving component, a syringe, and a nebulizing head. The driving component is mounted on the operating table. The syringe includes a tube body and a plunger. The tube body contains the vaccine and has an opening. A portion of the plunger is located within the tube body, and one end is connected to the driving component. The plunger is configured to move relative to the tube body under the drive of the driving component, thereby ejecting the vaccine from the opening. The nebulizing head is detachably connected to the opening and can enter the nasal cavity for nebulizing the vaccine. This technical solution uses a driving component to push the plunger, achieving automatic vaccine ejection, which improves the efficiency of vaccine administration and reduces the effort required by medical personnel.

[0016] The above and other objects, advantages and features of the present invention will become more apparent to those skilled in the art from the following detailed description of specific embodiments of the invention in conjunction with the accompanying drawings. Attached Figure Description

[0017] The following sections will describe some specific embodiments of the invention in detail by way of example and not limitation, with reference to the accompanying drawings. The same reference numerals in the drawings denote the same or similar parts or portions. Those skilled in the art should understand that these drawings are not necessarily drawn to scale. In the drawings: Figure 1 This is a schematic structural diagram of a vaccine nebulizer according to an embodiment of the present invention; Figure 2 This is a schematic structural diagram of an atomizing chip according to an embodiment of the present invention.

[0018] Figure label: 100-Vaccine nebulizer, 10-Operating table, 20-Driver, 30-Instrument, 40-Nebulizer head, 50-Guide rail, 60-Conduit, 11-Nebulization button, 12-Propulsion button, 13-Reset button, 14-Display screen, 31-Push rod, 32-Tube body, 33-Tube port, 41-Nebulization chip, 411-First flow channel, 412-Second flow channel, 413-Liquid inlet. Detailed Implementation

[0019] Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, and should not be construed as limiting the present invention.

[0020] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature, that is, include one or more of that feature. In the description of this invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified. When a feature "includes or contains" one or more of the features it encompasses, unless otherwise specifically stated, this indicates that other features are not excluded and may be further included.

[0021] Unless otherwise expressly specified and limited, the terms "connection," "installation," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art should be able to understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0022] Unless otherwise specified, all terms (including technical and scientific terms) used in the description of this embodiment have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.

[0023] Figure 1 This is a schematic structural diagram of a vaccine nebulizer 100 according to an embodiment of the present invention. Figure 1 As shown, in one specific embodiment, the vaccine nebulizer 100 includes an operating table 10, a drive unit 20, a syringe 30, and an nebulizing head 40. The drive unit 20 is mounted on the operating table 10. The syringe 30 includes a tube 32 and a plunger 31. The tube 32 is used to contain the vaccine and has an opening 33. A portion of the plunger 31 is located inside the tube 32, and one end is connected to the drive unit 20. The plunger 31 is configured to move relative to the tube 32 under the drive of the drive unit 20, thereby pushing the vaccine out of the opening 33. The nebulizing head 40 is detachably connected to the opening 33 and can enter the nasal cavity for nebulizing the vaccine.

[0024] This embodiment uses a drive component 20 to push the push rod 31, which realizes the automatic dispensing of the vaccine, improves the efficiency of vaccine administration, and is less strenuous for medical staff.

[0025] In some embodiments, the vaccine nebulizer 100 further includes a guide rail 50, which is mounted on the operating table 10, and the drive member 20 is slidably connected to the guide rail 50. This embodiment designs the guide rail 50 to guide the drive member 20, thereby improving the stability of the drive member 20's movement. It can be understood that the drive member 20 can move together with the push rod 31.

[0026] In some embodiments, the drive unit 20 is an electromechanical automation device, whose main function is to fix the syringe 30 and provide sufficient thrust to the plunger 31 of the syringe 30. This power source can be a motor, transducer, or actuator that moves axially, that is, it has a form that moves axially along with the plunger 31 of the syringe 30. The stroke of the motor, transducer, or actuator along the axial direction is generally limited, but it can still ensure that a single push is sufficient to meet the travel required for one dose of vaccine, providing sufficient thrust to complete one nebulization.

[0027] In some embodiments, the atomizing head 40 includes an atomizing chip 41, which has a first flow channel 411 and a second flow channel 412. The outlets of the first flow channel 411 and the second flow channel 412 are arranged opposite to each other, such that the vaccine flowing out of the first flow channel 411 collides with the vaccine flowing out of the second flow channel 412, thereby achieving atomization. Here, the atomizing chip 41 has a liquid inlet 413, which is connected to both the first flow channel 411 and the second flow channel 412. The liquid in the liquid inlet 413 is pressurized by thrust, forming two jets at the outlets of the first flow channel 411 and the second flow channel 412. The angle of the jets is precisely designed so that, under sufficiently large thrust, the two jets will collide, breaking the cohesion of the liquid and forming dispersed tiny particles, thereby achieving the atomization effect.

[0028] In some embodiments, the dimensions of the first flow channel 411 and the second flow channel 412 are both in the micrometer range. This atomizing chip 41 can be fabricated on a silicon substrate by photolithography and etching, and then the silicon substrate is bonded to glass for sealing. This is a typical MEMS process, so it is suitable for mass production. Under mass application, the manufacturing cost of the entire atomizing head 40 is low, and it can be used as a disposable medical consumable.

[0029] The atomizing head 40 in this embodiment can provide a smaller droplet diameter, meeting the requirement of 1-10μm, and has good atomization performance.

[0030] In some embodiments, the syringe 30 tube wall is made of borosilicate glass with high strength and pressure resistance, the ends of the tube wall are connected by metal, and the inside is a metal push rod 31. The head of the push rod 31 is preferably made of a piston made of Teflon material with good friction resistance and sealing performance.

[0031] The syringes 30 made of borosilicate glass are available in various capacities. With a fixed length, a larger capacity syringe 30 can hold more doses of inoculation solution. This larger capacity corresponds to a larger piston diameter and inner wall diameter on the plunger 31, requiring greater thrust for nebulization. A smaller capacity syringe 30 holds fewer doses of inoculation solution, but has a smaller piston diameter and inner wall diameter on the plunger 31, requiring less thrust for nebulization.

[0032] With a fixed capacity for syringe 30, a larger inner diameter of the tube results in a shorter length for syringe 30, leading to a shorter stroke for the electromechanical automation device. Conversely, a smaller inner diameter results in a longer length for syringe 30, leading to a longer stroke for the electromechanical automation device.

[0033] In some embodiments, the atomizing head 40 also includes a nasal inhaler, which is hemispherical in shape. The nasal inhaler structure designed in this embodiment is adaptable to the human nasal cavity. Here, the entire outer shell of the atomizing head 40 is made of plastic.

[0034] In some embodiments, the vaccine nebulizer 100 further includes a conduit 60, one end of which is connected to the port 33, and the other end is connected to the nebulizer head 40. The conduit 60 is made of a flexible material and can be understood as a soft conduit 60. The function of the conduit 60 is to expand the spatial range of motion of the nebulizer head 40. It should be noted that the conduit 60 is not mandatory; the nebulizer head 40 can also be directly connected to the syringe 30.

[0035] In some embodiments, the vaccine nebulizer 100 further includes a Luer connector, which is connected to both the port 33 and the nebulizer head 40. The Luer connector has a spiral structure, which ensures airtightness while also ensuring ease of installation and disassembly.

[0036] In some embodiments, the vaccine nebulizer 100 further includes a controller connected to the drive unit 20 for controlling the operation of the drive unit 20.

[0037] In some embodiments, the control panel 10 is provided with an atomization button 11, a push button 12, and a reset button 13, all of which are connected to a controller. When the push button is activated, the controller controls the drive unit 20 to move the push rod 31 and moves the drive unit 20 along the guide rail 50 to push the vaccine out of the tube 32. When the atomization button 11 is activated, the controller controls the atomization head 40 to operate, thereby atomizing the vaccine. When the reset button is activated, the controller controls the drive unit 20 to reset the push rod 31.

[0038] In some embodiments, the control panel 10 is provided with a display screen 14, which is used to display information on whether the vaccine has been dispensed and whether it has been atomized, so that medical staff can continue to the next step of the operation.

[0039] This embodiment increases the capacity of the syringe 30, which can meet the needs of multiple doses of vaccine administration with a single injection. This can further reduce the frequency of medication extraction by medical staff, thereby improving vaccination efficiency.

[0040] In this embodiment, medical staff first draw the vaccine into the tube opening 33 through the syringe 30, then connect the plunger 31 of the syringe 30 to the drive unit 20, then connect the nebulizer head 40 to the tube opening 33 through the conduit 60 or Luer connector, and finally operate the operating table 10 to make the drive unit 20 push the plunger 31 to realize the ejection and nebulization of the vaccine.

[0041] The preparation work for medical staff before vaccination is as follows: draw enough vaccine solution into syringe 30; return the drive component 20 to its original position and connect it to syringe 30; install catheter 60 and nebulizer head 40. The nebulizer head 40 needs to be replaced after each vaccination and is a consumable.

[0042] The procedure for a single vaccination by medical staff is as follows: Install the nebulizer head 40 and instruct the recipient to prepare for vaccination. Then, aim the nebulizer head 40 at the recipient's nasal cavity. Next, operate the push button and nebulization button 11 on the control panel 10 in sequence. After approximately 1-3 seconds, remind the recipient to leave. Finally, remove the nebulizer head 40. Repeat this process until the vaccine solution in the syringe 30 is completely consumed. Because the entire process is highly automated and requires no manual operation by medical staff, it saves time and labor, helping to improve the efficiency of medical staff in large-scale inhaled vaccination.

[0043] Compared to traditional injectable vaccines, this inhaled vaccine eliminates the need for injection, reducing recipients' fear of needles and improving vaccination compliance. This embodiment utilizes an automated vaccine delivery system, making the vaccination process convenient and rapid, reducing the workload of medical staff, and facilitating large-scale inhaled vaccine administration.

[0044] Therefore, those skilled in the art should recognize that although numerous exemplary embodiments of the present invention have been shown and described in detail herein, many other variations or modifications conforming to the principles of the present invention can be directly determined or derived from the disclosure of the present invention without departing from the spirit and scope of the invention. Thus, the scope of the present invention should be understood and construed as covering all such other variations or modifications.

Claims

1. A vaccine atomizing device, characterized in that, include: Control panel; The driving component is mounted on the operating table; A syringe includes a tube body and a plunger, the tube body being used to contain a vaccine and having an opening, a portion of the plunger being located within the tube body and one end being connected to a drive member, the plunger being configured to move relative to the tube body under the drive of the drive member, thereby ejecting the vaccine from the opening; The nebulizer head is detachably connected to the tube opening. The nebulizer head can enter the nasal cavity and is used to nebulize the vaccine.

2. The vaccine atomizing device according to claim 1, characterized in that, Also includes: A guide rail is mounted on the operating table, and the drive component is slidably connected to the guide rail.

3. The vaccine atomizing device according to claim 1, characterized in that, The atomizing head includes an atomizing chip, which has a first flow channel and a second flow channel. The outlets of the first flow channel and the second flow channel are arranged opposite to each other, so that the vaccine flowing out of the first flow channel collides with the vaccine flowing out of the second flow channel, thereby achieving atomization.

4. The vaccine atomizing device according to claim 3, characterized in that, The dimensions of both the first flow channel and the second flow channel are in the micrometer range.

5. The vaccine atomizing device according to claim 4, characterized in that, The atomizing head also includes a nasal inhaler, which is hemispherical in shape.

6. The vaccine nebulizer according to any one of claims 1-5, characterized in that, Also includes: The conduit is connected at one end to the tube opening and at the other end to the atomizing head.

7. The vaccine nebulizer according to any one of claims 1-5, characterized in that, Also includes: The Luer connector is connected to both the nozzle and the atomizing head.

8. The vaccine nebulizer according to any one of claims 1-5, characterized in that, Also includes: A controller, connected to the drive unit, is used to control the operation of the drive unit.

9. The vaccine atomizing device according to claim 8, characterized in that, The control panel is equipped with an atomization button, a propulsion button, and a reset button, all of which are connected to the controller. When the push button is activated, the controller controls the drive unit to move the push rod to push the vaccine out of the tube; When the nebulization button is activated, the controller controls the nebulization head to work, thereby nebulizing the vaccine; When the reset button is activated, the controller controls the drive unit to reset the push rod.

10. The vaccine nebulizer according to any one of claims 1-5, characterized in that, The control panel is equipped with a display screen, which is used to display information such as whether the vaccine has been dispensed and whether it has been nebulized.

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