A culture system

The design of the culture system enables automatic gas path control and non-removable observation of organ-on-a-chip, solving the problem of inconvenient observation in traditional culture processes and improving observation efficiency and culture results.

CN120966625BActive Publication Date: 2026-07-24XINSHENG INNOVATION (BEIJING) TECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
XINSHENG INNOVATION (BEIJING) TECHNOLOGY CO LTD
Filing Date
2025-07-11
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

Traditional organ-on-a-chip culture suffers from inconvenient observation, especially when the organ needs to be removed from the culture box, which affects the culture effect and is complicated to operate.

Method used

A culture system was designed, comprising a culture device, an imaging device, and a pressure supply device. The gas path interface is automatically connected or disconnected through a gas delivery component and a drive mechanism. Combined with the imaging device, the organ-on-a-chip can be observed without removing it, thus integrating the culture and observation functions of organ-on-a-chip.

Benefits of technology

It simplifies the observation process of organ-on-a-chip, improves observation efficiency, reduces the risk of contamination, and simulates the complex microenvironment of organs in the body, making it more convenient for researchers to use.

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Abstract

The application discloses a culture system, and relates to the technical field of organoids. The culture system comprises a culture device, an imaging device, and a pressure supply device. The culture device comprises a first base, a gas guide assembly, and a first driving mechanism. The first base has a bearing part for bearing a culture box. The gas guide assembly has a plurality of first gas ports and a plurality of second gas ports in communication. The first driving mechanism is installed on the first base and is used for driving the gas guide assembly to move, so that the second gas ports of the gas guide assembly are in communication or disconnected with gas path interfaces of the culture box. The imaging device is arranged opposite to an observation window of the culture box along a third direction. The pressure supply device comprises a positive pressure supply assembly and a negative pressure supply assembly. The positive pressure supply assembly has a first gas outlet in communication with some of the first gas ports, so as to provide positive pressure to the gas guide assembly. The negative pressure supply assembly has a second gas inlet in communication with the other first gas ports, so as to provide negative pressure to the gas guide assembly.
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Citation Information

Patent Citations

  • JP2005519602A

  • US20070148764A1