Dual-mode ablation treatment system based on tissue characteristic automatic matching

Abstract

The invention discloses a dual-mode ablation treatment system based on tissue characteristic automatic matching, and the system comprises a power conversion circuit which is used for converting a 220V AC commercial power into a DC power required by the system and meeting the EMC standard; the system control circuit is used for scheduling each module to work, receiving a processing instruction and controlling a machine to respond; the parameter display circuit is used for displaying system parameters and states; the system has the advantages that radiofrequency ablation and microwave ablation technologies are innovatively integrated, tissue impedance signals are collected in real time through the impedance detection circuit, the focus characteristics are automatically judged through the system control circuit, and when impedance is small, the system is automatically switched to a microwave ablation mode; when the impedance is too large, the radio frequency ablation mode is automatically switched to; manual equipment replacement or manual mode switching is not needed, the problem that independent equipment is low in treatment efficiency is solved, and incomplete ablation or normal tissue damage caused by manual judgment deviation is avoided.

Description

Technical Field

[0001] This invention belongs to the technical field of ablation therapy systems, specifically relating to a dual-mode ablation therapy system based on automatic matching of tissue characteristics. Background Technology

[0002] In the field of minimally invasive interventional therapy, radiofrequency ablation and microwave ablation are two commonly used methods for lesion ablation. Radiofrequency ablation utilizes a high-frequency current of 300-750kHz, delivered to the lesion tissue via an ablation needle and patch electrodes. This causes high-speed oscillation and friction of ions within the tissue, generating a high temperature of 60-100℃, which induces protein denaturation and coagulative necrosis in the target area cells. The single-point ablation diameter is typically 2-3cm. Although the ablation speed is relatively slow, it offers good controllability of the ablation range and easy adjustment of the thermal field, making it suitable for ablation sites adjacent to the thyroid gland. Treatment of lesions in important structures such as the kidney hilum; microwave ablation technology uses high-frequency electromagnetic waves of 915MHz or 2450MHz. A microwave antenna is placed into the target tissue through a puncture needle, causing water molecules in the tissue to vibrate and rub at high speed, generating a high temperature of 60-150℃, which destroys the proteins and DNA of tumor cells, achieving irreversible coagulative necrosis. Its single-point ablation diameter can reach 3-8cm, with strong penetration and not limited by tissue impedance. However, the range controllability is poor, and the high-heat area is prone to damaging adjacent organs such as the intestines and diaphragm, requiring auxiliary isolation techniques.

[0003] In existing technologies, radiofrequency ablation devices and microwave ablation devices are mostly independent, requiring the switching of devices according to the lesion condition during clinical treatment. This is cumbersome and inefficient. Some devices that attempt to integrate the two technologies cannot automatically match the ablation mode according to tissue characteristics and still rely on manual judgment for switching. This not only increases the difficulty of operation for medical staff but may also lead to incomplete ablation or damage to normal tissue due to judgment errors. In addition, existing devices have shortcomings in self-test reliability, needle compatibility detection, and energy discharge protection, making it difficult to meet the high requirements of clinical treatment safety and precision. Summary of the Invention

[0004] The purpose of this invention is to provide a dual-mode ablation treatment system based on automatic matching of tissue characteristics, which integrates radiofrequency and microwave ablation technologies. It identifies tissue characteristics in real time through impedance detection, automatically switches ablation modes, and optimizes self-testing, needle bar identification and energy protection mechanisms to improve treatment efficiency and safety.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a dual-mode ablation therapy system based on automatic tissue characteristic matching, comprising... A power conversion circuit is used to convert 220V AC mains power into DC power required by the system and to meet EMC specifications. The system control circuit is used to schedule the work of each module, receive and process instructions, and control the machine to respond. A parameter display circuit, used to display system parameters and status; A radio frequency (RF) generating circuit is used to respond to the scheduling of the system control circuit and output RF energy of corresponding power. An impedance detection circuit is used to collect the current and voltage signals of the output system and feed the data back to the system control circuit for impedance calculation. A microwave generating circuit, wherein the microwave generating circuit is used to output microwave energy; A high-voltage start-up circuit is used to drive the microwave generator circuit to start. An electrostatic discharge (ESD) protection circuit, which is used to isolate electrostatic interference; An output switching circuit is used to switch between microwave output energy and radio frequency output energy. A power detection circuit, wherein the power detection circuit is used to detect the output power; A temperature monitoring circuit, which is used to monitor the temperature signal fed back by the ablation needle; Needle bar identification circuit, which is used to identify the model of ablation needle; An energy output interface, wherein the energy output interface is used to transmit ablation energy; A signal feedback interface, wherein the signal feedback interface is used to transmit feedback signals; An interactive button interface is provided for users to adjust system parameters and control system operation.

[0006] As a preferred technical solution of the present invention, the power conversion circuit adopts an AC-DC transformer with a power supply of 500W and outputs 24V DC power; the system control circuit integrates a step-down module to convert the 24V voltage into 5V and 3.3V voltages for use by each module.

[0007] As a preferred technical solution of the present invention, the parameter display circuit adopts a display module, which is connected to the system control circuit through a serial port, and can display working parameters, running status and operation prompts through touch feedback.

[0008] As a preferred technical solution of the present invention, the impedance detection circuit includes a current transformer, a sampling coil and an operational amplifier. The current transformer and the sampling coil collect the current and voltage signals at the output terminal. The operational amplifier reduces the signal proportionally and feeds it back to the system control circuit, which then calculates the impedance.

[0009] As a preferred embodiment of the present invention, the output switching circuit includes a relay, a driver chip, and a multi-functional resistor; the relay switches the energy output type in response to the system control circuit signal, and the multi-functional resistor acts as a self-test resistor during self-test and as a discharge resistor after the power output ends, guiding the discharge of excess energy.

[0010] As a preferred technical solution of the present invention, the temperature monitoring circuit adopts a T-type thermocouple detection chip, coupled with a common-mode filter, and reads the melting needle temperature signal through the signal feedback interface. When the temperature exceeds the safety warning value, the system control circuit stops power output and alarms.

[0011] As a preferred technical solution of the present invention, the needle bar identification circuit is an ADC reading circuit. It reads the resistance value of the built-in identification resistor of the de-flashing needle through the signal feedback interface, and compares it with the built-in model table of the system using a lookup table method to determine whether the needle bar model matches. If they do not match, the system locks and prompts an error.

[0012] As a preferred technical solution of the present invention, it also includes a power output mode, which includes a manual mode and an automatic mode; in the manual mode, the system outputs radio frequency or microwave energy according to the user's selection; in the automatic mode, the system automatically switches between radio frequency or microwave ablation mode according to the impedance value fed back by the impedance detection circuit.

[0013] As a preferred technical solution of the present invention, it also includes an operating mode, which includes an impedance mode and a time mode; in the impedance mode, the power output stops after the impedance reaches a set value; in the time mode, the power output continues until the set time is reached and then stops.

[0014] As a preferred technical solution of the present invention, the interactive button interface is treated with electrostatic protection and forms a dual interactive mode with the touch function of the parameter display circuit.

[0015] Compared with the prior art, the beneficial effects of the present invention are: This system innovatively integrates radiofrequency ablation and microwave ablation technologies. It collects tissue impedance signals in real time through an impedance detection circuit, and the system control circuit automatically judges the characteristics of the lesion. When the impedance is too low, it automatically switches to microwave ablation mode; when the impedance is too high, it automatically switches to radiofrequency ablation mode. There is no need to manually change equipment or manually switch modes. This solves the problem of low treatment efficiency of independent equipment and avoids incomplete ablation or damage to normal tissue caused by human judgment errors. It achieves the treatment goal of "rapid coverage of large lesions and precise inactivation of small lesions". The system supports adjusting the switching impedance value between microwave and radio frequency modes in the settings page, which can optimize the treatment plan according to the physiological characteristics of different organs and tissues. For example, lung tissue has many cavities, so the switching impedance can be increased to avoid excessive diffusion of microwave energy; liver tissue is rich in blood and has low impedance, so the switching impedance can be decreased to ensure rapid microwave ablation while reducing energy waste and further improving the treatment's targeting. The system has both a touch function for parameter display circuitry and a physical operation function for interactive button interface. The touch function supports intuitive parameter setting and mode selection, which is suitable for precise operation. The physical buttons are treated with electrostatic protection and can still operate stably in complex surgical environments, meeting the needs of diverse clinical scenarios and reducing the difficulty of operation for medical staff. After powering on, the system automatically completes self-testing through the built-in multi-functional resistor in the output switching circuit, without manual triggering, and quickly confirms the circuit status. When the ablation needle is connected, the needle bar identification circuit automatically determines the model compatibility by reading the resistance value of the marked resistor, without the need for manual verification of specifications, which saves operation time, avoids treatment risks caused by human error, and improves process efficiency. The multi-functional resistor built into the output switching circuit automatically switches to a "bleeding resistor" after the power output is finished, guiding the excess energy remaining in the energy output circuit to the resistor end for consumption, avoiding residual energy from breaking down the relay or being reflected back to the radio frequency / microwave generating circuit. This solves the problem of core component damage caused by the inability to bleed energy in traditional equipment, significantly extending the service life of the equipment and reducing clinical maintenance costs. Full-link electrostatic protection ensures circuit stability: The electrostatic protection circuit (TVS tube + ESD tube) is integrated into key modules such as parameter display circuit, interactive button interface, and signal feedback interface. It can isolate external electrostatic interference, prevent electrostatic breakdown of precision components such as MCU chip and display module, and ensure that the system can still operate stably in a dry surgical environment, avoiding equipment failure or treatment interruption caused by electrostatic discharge.

[0016] This system integrates two ablation techniques into one device, significantly reducing the floor space required for the operating room and lowering the costs of hospital equipment procurement and space layout. It is especially suitable for minimally invasive interventional treatment rooms with limited space. Attached Figure Description

[0017] Figure 1 This is a functional block diagram of the power conversion circuit of the present invention; Figure 2 This is a schematic diagram of the system control circuit of the present invention; Figure 3 This is a circuit diagram of the output switching circuit of the present invention; Figure 4 This is a detailed circuit diagram of the temperature detection circuit of the present invention; Figure 5 This is a detailed circuit diagram of the needle bar recognition circuit of the present invention; Figure 6 This is a block diagram of the self-testing method of the present invention; Figure 7 This is a flowchart of the algorithm of the present invention; Figure 8 This is a system block diagram of the present invention. Detailed Implementation

[0018] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0019] Example 1 Please see Figures 1-8 This is the first embodiment of the present invention, which provides a dual-mode ablation therapy system based on automatic tissue characteristic matching, including... The power conversion circuit uses the MQF500E-24S model, which can provide 500W of power. It is an AC-DC transformer that complies with EMC safety standards and is used to convert 220V AC mains power into 24V DC power for the machine, providing sufficient power to the system. The system control circuit uses an MCU chip and peripheral circuits to schedule the other circuit modules, ensure the normal operation of the entire system, and interface with user operation modules such as parameter display circuit and interactive button interface. It is responsible for receiving user commands and controlling the machine to respond. The parameter display circuit uses a DMG10600K070_03W model display module with a resolution of 1024*600. It is electrically connected to the system control circuit and communicates via a serial port. It is responsible for displaying relevant data of machine operation under the scheduling of the system control circuit, providing real-time reminders of the system's operating status, and has a touch feedback function. The radio frequency (RF) generation circuit, also known as the RF generation module circuit, is detailed in CN119867906A, a multi-channel RF energy ablation output system and method, which includes a programmable voltage regulation circuit and an RF energy generation circuit. These circuits are electrically connected to the system control circuit and are responsible for responding to the scheduling of the system control circuit and outputting RF energy of corresponding power. Impedance detection circuit, which includes current transformer, sampling coil and operational amplifier. The current transformer and sampling coil collect the current and voltage signals at the output terminal. The operational amplifier reduces the signal proportionally and feeds it back to the system control circuit, which then calculates the impedance. The microwave generating circuit, which consists of the magnetron and connecting wires, is electrically connected to the high-voltage starting circuit and is responsible for outputting the microwave energy of this system. The high-voltage starting circuit, also known as the microwave starting board, is responsible for receiving small-amplitude control signals generated by the system control circuit and outputting corresponding high voltage according to the amplitude of the signal to start the magnetron to output microwave energy. Electrostatic discharge protection circuit, namely TVS diode and ESD diode, is responsible for isolating the system from possible electrostatic interference from the outside and ensuring that the system’s precision components are not damaged by electrostatic discharge. The output switching circuit, namely the relay and its control circuit, is responsible for responding to the control signals of the system control circuit and switching the type of signal connected to the energy output interface to complete the switching between microwave output energy and radio frequency output energy. The power detection circuit, also known as the power detection module, is responsible for detecting the output power of the system and feeding this data back to the system control circuit in real time. The system control circuit then transmits the data to the parameter display circuit for display. The temperature monitoring circuit uses a dedicated T-type thermocouple detection chip to read the temperature signal fed back by the energy carrier ablation needle and transmit it to the system control circuit. The system control circuit then transmits it to the parameter display circuit for display and provides an alarm when the temperature exceeds the safe range. The needle bar identification circuit is an ADC reading circuit. It reads the resistance value of the built-in marking resistor of the de-flashing needle through the signal feedback interface, and compares it with the built-in model table of the system using a lookup table method to determine whether the needle bar model matches. If they do not match, the system locks and prompts an error. The power output interface, also known as the BNC interface, is used for microwave and radio frequency power output because it can transmit power signals with high quality. The signal feedback interface, also known as the aviation connector, is used to connect signals such as temperature and needle bar information to this system because it has a limit switch and can be selected with multiple core numbers. Interactive button interface: The interactive button interface is a regular button that has been treated with electrostatic protection before being connected to the system, so that users can easily adjust system parameters and control the operation of the system.

[0020] Example 2 Please see Figures 1-8 This is the second embodiment of the present invention, which is based on the previous embodiment, but differs in that: a dual-mode ablation treatment system based on automatic tissue characteristic matching, the operation of which includes the following steps: (1) When the equipment is turned on, the power conversion circuit works to provide a stable operating voltage to each component; It should be noted that this system adopts a multi-stage power supply mode. Since different modules of this system require different operating voltages, a 24V power supply is provided by the power conversion circuit, and a 5V and 3.3V output is provided by the step-down module integrated on the system control circuit.

[0021] (2) The system control circuit initializes the system hardware and software resources, detects whether the working status of the internal circuit is normal, and feeds back the working information of the circuit to the parameter display circuit.

[0022] (3) If the system detects that the internal circuit is not working properly, it will send an error message to the parameter display circuit and lock the system, and will no longer provide ablation output function to prevent accidents from happening; It should be noted that this system has a unique self-testing method, which is implemented by embedding a multi-functional resistor in the output switching circuit. Through different combinations of relay opening and closing, this resistor serves as a buffer between the energy carrying system and the relay. During internal self-testing, the relay connects the energy output system to the multi-functional resistor, which then acts as a self-testing resistor. The system outputs a small amount of power instantaneously to the self-testing resistor. At the same time, the power detection circuit and impedance detection circuit operate to detect whether the power and impedance correspond to the resistance value of the self-testing resistor. If normal, the self-test is passed; if abnormal, an alarm is triggered.

[0023] (4) If the system detects that the internal circuit is working normally, the system control circuit and the control parameter display circuit will display the standby interface, waiting for the user to operate.

[0024] (5) Users can set system operating parameters through the touch function of the parameter display circuit or through the interactive button interface, and connect the energy carrying system (ablation needle) that is compatible with this system.

[0025] (6) After the user confirms that the parameter settings are correct, press the power output button in the interactive button interface. The system control circuit reads the parameters of the needle bar identification circuit to determine whether the specifications of the inserted energy carrying system (ablation needle) match the model of the machine and whether the parameters are set.

[0026] (7) If the model matching fails, the system control circuit control parameter display circuit will display an error message and lock the system, waiting for the user to insert the correct model of ablation needle product; It should be noted that the needle bar identification circuit used in this invention has electrostatic protection function, and the needle bar model identification function is realized by the following method: First, each model of ablation needle integrates a different identification resistor. This resistor is connected to the system through a signal feedback interface. The system reads the resistance value of the resistor and compares it with the model judgment table built into the system using a lookup table method, thereby obtaining the specific needle bar model. After obtaining the model, the system parameters can be restricted according to the model information. If the inserted model is not compatible with the machine model, the system control circuit controls the parameter display circuit to issue an alarm prompt.

[0027] (8) If the model is successfully matched, the system control circuit will first determine the power output mode set by the user.

[0028] (9) If the power output mode set by the user is manual mode, then single-mode output will be performed according to the output method (RF or microwave) set by the user.

[0029] (10) If the power output mode set by the user is automatic mode, the system control circuit reads the signal returned by the impedance detection circuit in real time to calculate the impedance information, and selects the form of power output according to the impedance information. If the impedance is too small, microwave ablation is used for fast ablation. If the impedance is too large, radio frequency is used for slow supplementary ablation. It should be noted that the present invention determines the impedance near the application point of the load-bearing system using the following method: In RF output mode, the system obtains the output voltage and current information through the current transformer and sampling coil in the impedance detection circuit, and then proportionally reduces it to the voltage range that the system control circuit can read through the operational amplifier. The system control circuit then reads and calculates the impedance, which is then displayed by the parameter display circuit. In microwave output mode, the system still outputs a small amount of radio frequency energy as a probe signal through the aforementioned radio frequency output circuit to obtain the impedance near the application point of the bearing system. Meanwhile, the impedance value for switching between microwave and radio frequency output energy forms is adjustable in the system settings page. This parameter is adjustable to facilitate handling tumor tissues in different adaptation areas. For example, if there are many cavities in the lungs, the switching impedance can be adjusted to be larger; if the liver tissue has sufficient blood supply, the switching impedance can be appropriately reduced.

[0030] (11) In addition to the two power output modes, there are two more operating modes, as follows: If the user selects impedance mode, the system control circuit reads the impedance information in real time and stops power output when the impedance reaches the set value. If the user selects the time mode, the system control circuit will output power for a fixed duration according to the ablation time set by the user, and stop outputting power after the set time is reached. (12) During the above power output process, the power detection circuit is responsible for detecting the power output of the system in real time and transmitting the value to the system control circuit, which then displays it on the parameter display circuit.

[0031] (13) During the above power output process, the temperature monitoring circuit displays the temperature of the energy carrying system (ablation needle) in real time. When the temperature exceeds the warning value, the system control circuit will stop the power output and issue an alarm on the parameter display circuit.

[0032] (14) After the power output is completed, the system control circuit controls the machine to enter the standby state, waiting for the user's next operation; It should be noted that this invention employs a unique circuit protection mechanism. When the power output ends, the output switching circuit of this system immediately disconnects the energy output circuit from the energy carrying system. However, the energy output of the energy output circuit cannot be reduced to zero instantaneously. If this energy has nowhere to be released after disconnection, it will be output to the relay terminal or reflected back into the energy output system, leading to a reduction in the service life of the relay and the energy output system. Therefore, this system is designed with a multi-functional resistor circuit, which acts as a self-test resistor during power-on self-test and as a discharge resistor when power output ends. Specifically, when the power output ends, the relay connects the energy output system to both ends of the multi-functional resistor. At this moment, the output of the energy carrying system will instantly drop to zero, and the excess energy generated after the energy output system stops will also be guided to the multi-functional resistor terminal for discharge.

[0033] Although embodiments of the invention have been shown and described in detail above, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A dual-mode ablation therapy system based on automatic tissue characteristic matching, characterized in that: include A power conversion circuit is used to convert 220V AC mains power into DC power required by the system and to meet EMC specifications. The system control circuit is used to schedule the work of each module, receive and process instructions, and control the machine to respond. A parameter display circuit, used to display system parameters and status; A radio frequency (RF) generating circuit is used to respond to the scheduling of the system control circuit and output RF energy of corresponding power. An impedance detection circuit is used to collect the current and voltage signals of the output system and feed the data back to the system control circuit for impedance calculation. A microwave generating circuit, wherein the microwave generating circuit is used to output microwave energy; A high-voltage start-up circuit is used to drive the microwave generator circuit to start. An electrostatic discharge (ESD) protection circuit, which is used to isolate electrostatic interference; An output switching circuit is used to switch between microwave output energy and radio frequency output energy. A power detection circuit, wherein the power detection circuit is used to detect the output power; A temperature monitoring circuit, which is used to monitor the temperature signal fed back by the ablation needle; Needle bar identification circuit, which is used to identify the model of ablation needle; An energy output interface, wherein the energy output interface is used to transmit ablation energy; A signal feedback interface, wherein the signal feedback interface is used to transmit feedback signals; An interactive button interface is provided for users to adjust system parameters and control system operation.

2. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The power conversion circuit uses an AC-DC transformer with a power supply of 500W and outputs 24V DC power; the system control circuit integrates a step-down module to convert the 24V voltage into 5V and 3.3V voltages for use by each module.

3. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The parameter display circuit uses a display module, which is connected to the system control circuit via a serial port. It can display working parameters, operating status, and operation prompts via touch feedback.

4. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The impedance detection circuit includes a current transformer, a sampling coil, and an operational amplifier. The current transformer and the sampling coil collect the current and voltage signals at the output terminals. The operational amplifier reduces the signal proportionally and feeds it back to the system control circuit, which then calculates the impedance.

5. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The output switching circuit includes a relay, a driver chip, and a multi-function resistor. The relay switches the energy output type in response to the system control circuit signal. The multi-function resistor acts as a self-test resistor during self-test and as a discharge resistor after the power output ends, guiding the discharge of excess energy.

6. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The temperature monitoring circuit uses a T-type thermocouple detection chip, paired with a common-mode filter. It reads the melting needle temperature signal through the signal feedback interface. When the temperature exceeds the safety warning value, the system control circuit stops power output and issues an alarm.

7. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The needle bar identification circuit is an ADC reading circuit. It reads the resistance value of the built-in identification resistor of the de-flashing needle through the signal feedback interface, and compares it with the built-in model table of the system using a lookup table method to determine whether the needle bar model matches. If they do not match, the system locks and prompts an error.

8. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: It also includes power output modes, which include manual mode and automatic mode; in manual mode, the system outputs radio frequency or microwave energy according to the user's selection; in automatic mode, the system automatically switches between radio frequency or microwave ablation mode according to the impedance value fed back by the impedance detection circuit.

9. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 8, characterized in that: It also includes operating modes, which include impedance mode and time mode; in impedance mode, power output stops after the impedance reaches a set value; in time mode, power output continues until the set time is reached and then stops.

10. The dual-mode ablation therapy system based on automatic tissue characteristic matching according to claim 1, characterized in that: The interactive button interface is electrostatic protected and forms a dual-interaction mode with the touch function of the parameter display circuit.

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