Reset method and electronic equipment

Abstract

The invention provides a reset method and electronic equipment, and relates to the technical field of medical treatment, in particular to the technical field of tumor tracking. The method comprises the following steps: acquiring a current two-dimensional image of a target object shot by an image guide device in image guide radiotherapy equipment from a preset angle under current fractional radiotherapy, and then acquiring a reference image of the target object under historical fractional radiotherapy and a first offset corresponding to the reference image, and finally, based on the current two-dimensional image of the target object, the reference image and the first offset, determining the current position offset of the target object under the current fractional radiotherapy. By means of the method, the accuracy of resetting the patient can be effectively improved.

Description

TECHNICAL FIELD

[0001] The present disclosure relates to the technical field of medical treatment, in particular to the technical field of tumor tracking, and specifically to a resetting method and an electronic device. BACKGROUND

[0002] Radiotherapy is a method of treating tumors by using radioactive rays. Cone Beam Computed Tomography (CBCT) image-guided technology is widely used in the field of radiotherapy. CBCT image-guided technology refers to: performing CBCT image guidance on a patient to obtain a CBCT image of the patient, then registering the CBCT image of the patient with a planning image of the patient to determine a setup deviation of the patient, and completing the setup of the patient through the setup deviation. The planning image is an image used when a treatment plan is formulated.

[0003] In recent years, the number of cancer patients is increasing year by year, and medical resources are tight, which leads to the fact that CBCT image guidance cannot be performed on patients at each radiotherapy in clinic. As a result, a resetting treatment method is proposed. Resetting treatment is generally applicable to the cases of light field lamps, laser lamps and setup coincidence.

[0004] However, ring accelerators generally do not have light field lamps, and the isocenter and virtual isocenter of the ring accelerator treatment are usually not coincident. In addition, the radiotherapy period of most patients is relatively long, so that the body state of the patient changes during radiotherapy, resulting in a change in the fit between the human body and the fixing device such as a mask, a thermoplastic film or a vacuum pad. Therefore, the method of correcting the position of the patient only according to the marker line and the laser line can cause a deviation between the tumor position of the patient during treatment and the tumor position in the planning image, and further affect the accuracy of resetting the patient. SUMMARY

[0005] The present disclosure provides a resetting method and an electronic device, which can reset a patient quickly based on a CBCT image guidance device, not only making the ring accelerator also capable of resetting treatment, but also improving the accuracy of resetting the patient.

[0006] In a first aspect, the present disclosure provides a resetting method, which comprises:

[0007] Under the current fraction radiotherapy, a two-dimensional image of a target object currently photographed by an image guidance device in an image-guided radiotherapy equipment from a preset angle is obtained, then a reference image of the target object under historical fraction radiotherapy and a first offset corresponding to the reference image are obtained, and finally a current position offset of the target object under the current fraction radiotherapy is determined based on the two-dimensional image of the target object currently, the reference image and the first offset.

[0008] The reference image is a two-dimensional image of the target object that is imaged at the same angle as the preset angle by using an image guiding device in historical fractionated radiotherapy. The first offset is a position offset of the target object obtained based on a two-dimensional image of the target object taken by the image guiding device in historical fractionated radiotherapy. The current position offset is used to reset the target object in at least two directions in the current fractionated radiotherapy, so that the position of the target object in at least two directions after resetting is consistent with the position of the target object in at least two directions adjusted based on the first offset in historical fractionated radiotherapy.

[0009] In some embodiments, based on the current two-dimensional image of the target object, the reference image and the first offset, the current position offset of the target object in the current fractionated radiotherapy is determined, comprising:

[0010] The current two-dimensional image of the target object and the reference image are registered to obtain a second offset, and the sum of the first offset and the second offset is taken as the current position offset of the target object in the current fractionated radiotherapy.

[0011] In some embodiments, based on the current two-dimensional image of the target object, the reference image and the first offset, the current position offset of the target object in the current fractionated radiotherapy is determined, comprising:

[0012] Based on the first offset, the current two-dimensional image of the target object is corrected to obtain a corrected two-dimensional image, and the corrected two-dimensional image and the reference image are registered to obtain the current position offset of the target object in the current fractionated radiotherapy.

[0013] In some embodiments, when the preset angle includes a first angle and a second angle, the first angle and the second angle are orthogonal to each other; when the preset angle includes one angle, the current two-dimensional image of the target object taken from the preset angle is a lateral two-dimensional image or an anterior-posterior two-dimensional image of the target object.

[0014] In some embodiments, the image guiding device includes at least one of a CBCT device, a CT device, and a magnetic resonance (MR) device.

[0015] In some embodiments, the image guiding device is a CBCT device, and the current two-dimensional image of the target object is a two-dimensional projection image. The reference image of the target object in historical fractionated radiotherapy is obtained by: obtaining a target two-dimensional projection image of the target object taken from the preset angle by using the CBCT device in historical fractionated radiotherapy, and taking the target two-dimensional projection image as the reference image of the target object in historical fractionated radiotherapy.

[0016] In some embodiments, the acquiring the target two-dimensional projection image of the target object under the historical fractionated radiotherapy and from the preset angle by the CBCT device comprises: acquiring a plurality of two-dimensional projection images of the target object under the historical fractionated radiotherapy and from different imaging angles by the CBCT device, and selecting, from the plurality of two-dimensional projection images, a two-dimensional projection image with the same imaging angle as the preset angle as the target two-dimensional projection image.

[0017] In some embodiments, the image guiding device is a CBCT device, and the current two-dimensional image of the target object is a two-dimensional projection image. The acquiring the reference image of the target object under the historical fractionated radiotherapy comprises: acquiring a CBCT image of the target object under the historical fractionated radiotherapy, digitally reconstructing the CBCT image at the preset angle to obtain a digitally reconstructed radiograph (DRR) image, and selecting the DRR image as the reference image of the target object under the historical fractionated radiotherapy.

[0018] The CBCT image is a three-dimensional reconstruction image generated by three-dimensional reconstruction of two-dimensional projection images of the target object under the historical fractionated radiotherapy and from different imaging angles by the CBCT device.

[0019] In some embodiments, the method further comprises:

[0020] storing the current two-dimensional image of the target object and the current position offset of the target object under the current fractionated radiotherapy, so as to be used as the reference image of the target object under the historical fractionated radiotherapy and the first offset corresponding to the reference image, respectively, in the next fractionated radiotherapy.

[0021] In some embodiments, the reference image of the target object under the historical fractionated radiotherapy is a reference image of the target object under the most recent historical fractionated radiotherapy.

[0022] In a second aspect, the disclosure also provides a resetting device, which comprises:

[0023] The first acquiring unit is configured to acquire, under the current fractionated radiotherapy, a current two-dimensional image of a target object taken from a preset angle by an image guiding device in an image-guided radiotherapy device. The reference image is a two-dimensional image with the same imaging angle as the preset angle in two-dimensional images of the target object taken by the image guiding device under the historical fractionated radiotherapy.

[0024] The second acquiring unit is configured to acquire a reference image of the target object under the historical fractionated radiotherapy and a first offset corresponding to the reference image. The first offset is a position offset of the target object based on two-dimensional images of the target object taken by the image guiding device under the historical fractionated radiotherapy.

[0025] The determining unit is configured to determine a current position offset of the target object under the current fractionated radiotherapy based on the current two-dimensional image of the target object, the reference image, and the first offset. The current position offset is used to reset the target object in at least two directions in the current fractionated radiotherapy, so that the position of the target object in at least two directions after the reset is consistent with the position of the target object in at least two directions after the adjustment based on the first offset under the historical fractionated radiotherapy.

[0026] In a third aspect, the present disclosure also provides an electronic device, which comprises a processor and a memory configured to store processor-executable instructions; wherein the processor is configured to execute the instructions to implement any of the optional reset methods in the first aspect.

[0027] By the above technical solution, only a two-dimensional image of the target object at a preset angle needs to be obtained, and the current position offset of the target object under the current fractionated radiotherapy can be obtained. Compared with CBCT image guidance for the target object, the above technical solution can effectively reduce the number of times of irradiation of the target object by kilovoltage (KV) rays, effectively shorten the imaging time of the target object, and achieve the effect of fast resetting of the target object.

[0028] In addition, in this way, the current position offset of the target object is determined based on the current two-dimensional image of the target object, in combination with the reference image of the target object under the historical fractionated radiotherapy and the first offset corresponding to the reference image, so as to reset the target object. The present scheme resets the target object based on a small amount of images, rather than relying only on the marker line and the laser line of the laser lamp in the radiotherapy device to reset the target object. Therefore, the present scheme can effectively improve the accuracy of resetting the patient. BRIEF DESCRIPTION OF DRAWINGS

[0029] The accompanying drawings serve to better understand the present scheme and do not constitute a limitation on the present disclosure. Among them:

[0030] Figure 1 A scene schematic diagram of an image-guided radiotherapy system provided by an embodiment of the present disclosure;

[0031] Figure 2 A method flowchart of a reset method provided by an embodiment of the present disclosure;

[0032] Figure 3 A method flowchart of another reset method provided by an embodiment of the present disclosure;

[0033] Figure 4 A method flowchart of another reset method provided by an embodiment of the present disclosure;

[0034] Figure 5A method flowchart of another reset method provided by an embodiment of the present disclosure;

[0035] Figure 6 A method flowchart of another reset method provided by an embodiment of the present disclosure;

[0036] Figure 7 A method flowchart of another reset method provided by an embodiment of the present disclosure;

[0037] Figure 8 A schematic block diagram of an electronic device provided by an embodiment of the present disclosure. DETAILED DESCRIPTION

[0038] The technical solutions in the embodiments of the present disclosure will be described clearly and completely below with reference to the drawings in the embodiments of the present disclosure. Obviously, the described embodiments are only part of the embodiments of the present disclosure, rather than all the embodiments. Based on the embodiments in the present disclosure, all other embodiments obtained by a person skilled in the art without creative work fall within the protection scope of the present disclosure.

[0039] In the description of the present disclosure, it should be understood that the orientation or positional relationship indicated by the terms “center”, “longitudinal”, “lateral”, “length”, “width”, “thickness”, “upper”, “lower”, “front”, “rear”, “left”, “right”, “vertical”, “horizontal”, “top”, “bottom”, “inner”, “outer” and the like is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present disclosure and simplifying the description, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present disclosure. In addition, the terms “first”, “second”, “third” are only for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features limited by “first”, “second”, “third” can explicitly or implicitly include one or more of the features. In the description of the present disclosure, the meaning of “multiple” is two or more, unless otherwise specifically limited.

[0040] In the description of this disclosure, the term "exemplary" is used to mean "serving as an example, illustration, or description." Any embodiment described as "exemplary" in this disclosure is not necessarily to be construed as being more preferred or advantageous than other embodiments. The following description is provided to enable any person skilled in the art to make and use this disclosure. Details are set forth in the following description for purposes of explanation. It should be understood that those skilled in the art will recognize that this disclosure can be made without using these specific details. In other instances, well-known structures and processes will not be described in detail to avoid obscuring the description of this disclosure with unnecessary detail. Therefore, this disclosure is not intended to be limited to the embodiments shown, but is consistent with the broadest scope of the principles and features disclosed herein.

[0041] It should be noted that since the method of this embodiment is executed in an imaging computer device, the processing objects of each imaging computer device exist in the form of data or information, such as time, which is essentially time information. It can be understood that if size, quantity, position, etc. are mentioned in subsequent embodiments, they all refer to the corresponding data so that the computer device can process them. Specific details will not be elaborated here.

[0042] Radiation therapy is a method of treating tumors using radioactive rays and is one of the main treatments for malignant tumors. CBCT image-guided technology is widely used in the field of radiation therapy. CBCT image-guided technology refers to: guiding the patient through CBCT images to obtain the patient's CBCT images; then registering the patient's CBCT images with the treatment plan images to determine the patient's positioning deviation; and finally, using this deviation to determine the patient's positioning. The treatment plan images are those used to develop the treatment plan.

[0043] In recent years, the number of cancer patients has been increasing year by year, leading to a shortage of medical resources. This makes it impossible to perform CBCT image guidance for every radiotherapy session. In practice, repositioning therapy can be used when CBCT guidance is not available. Repositioning therapy is typically suitable when the light field lamp, laser lamp, and positioning are aligned. During repositioning therapy, the marking lines on the patient's body, face mask, thermoplastic film, or vacuum pad need to be aligned with the laser line of the laser lamp in the radiotherapy equipment. Once aligned, the patient's positioning is considered complete.

[0044] However, the ring accelerator generally does not have a light field lamp, and the isocenter and the virtual isocenter of the ring accelerator treatment generally do not coincide, and in addition, the radiotherapy cycle of most patients is relatively long, so that the body state of the patient changes during the radiotherapy, resulting in a change in the fit between the human body and the fixing device such as a mask, a thermoplastic film or a vacuum pad, and therefore, the method of correcting the position of the patient only according to the mark line and the laser line can cause a deviation between the tumor position of the patient during the treatment and the tumor position in the planning image, and further affect the accuracy of the repositioning of the patient.

[0045] Based on the above technical problem, the repositioning method provided in the embodiments of the present disclosure can obtain a current two-dimensional image of a target object (for example, a patient) photographed by an image guiding device in an image guided radiotherapy device from a preset angle under current fractionated radiotherapy, then obtain a reference image of the target object under historical fractionated radiotherapy and a first offset corresponding to the reference image, and finally determine a current position offset of the target object under the current fractionated radiotherapy based on the current two-dimensional image of the target object, the reference image and the first offset.

[0046] The reference image is a two-dimensional image of the target object whose imaging angle is the same as the preset angle in the two-dimensional image of the target object photographed by the image guiding device under the historical fractionated radiotherapy. The first offset is a position offset of the target object obtained based on the two-dimensional image of the target object photographed by the image guiding device under the historical fractionated radiotherapy. The current position offset is used to reposition the target object in at least two directions under the current fractionated radiotherapy, so that the position of the target object in the at least two directions after the repositioning is consistent with the position of the target object in the at least two directions adjusted based on the first offset under the historical fractionated radiotherapy.

[0047] Through the above technical solution, only the two-dimensional image of the target object at the preset angle needs to be photographed to obtain the current position offset of the target object under the current fractionated radiotherapy, so that the ring accelerator can also be used for repositioning treatment, and in addition, compared with the CBCT image guiding of the target object, the above technical solution can effectively reduce the imaging times of the target object, so as to achieve the effects of quickly repositioning the target object and reducing the additional irradiation of the target object.

[0048] In addition, in this way, the current position offset of the target object is determined based on the current two-dimensional image of the target object, in combination with the reference image of the target object under the historical fractionated radiotherapy and the first offset corresponding to the reference image, so as to reposition the target object, thereby effectively improving the accuracy of repositioning the patient.

[0049] Figure 1A scene schematic diagram of an image-guided radiotherapy system provided by an embodiment of the present disclosure can include an image-guided radiotherapy device 101, an image computer device 102, and a control device 103.

[0050] The image-guided radiotherapy device 101 can include a gantry 104, and a radiotherapy head 105 and an image-guiding device disposed on the gantry 104, wherein the image-guiding device includes an imaging source 106 and a detector 107. The imaging source 106 is configured to emit a cone-beam imaging beam, and the detector 107 is configured to receive the imaging beam passing through a target object to generate a two-dimensional image of the target object.

[0051] In an embodiment of the present disclosure, the detector 107 can be a flat panel detector or a curved detector, and the embodiment of the present disclosure does not limit the form of the detector 107.

[0052] In an embodiment of the present disclosure, the image-guiding device can be at least one of a CBCT device, a CT device, and an MR device, that is, the image-guiding device can be a CBCT device, a CT device, or an MR device, or can include any two of a CBCT device, a CT device, and an MR device, or can include a CBCT device, a CT device, and an MR device. The embodiment of the present disclosure does not limit the form of the image-guiding device.

[0053] When the image-guiding device is a CBCT device, the imaging source 106 is an X-ray tube, and the detector 107 is a flat panel detector.

[0054] The radiotherapy head 105 includes a therapeutic radiation source configured to emit therapeutic radiation to the target object, and the light beam emitted by the therapeutic radiation source can include a particle beam (for example, a neutron beam, a proton beam, an electron beam, etc.), a photon beam (for example, an X-ray beam, a gamma ray beam), or a combination of a particle beam and a photon beam.

[0055] The gantry 104 can be a ring-shaped gantry, a C-shaped arm gantry, a drum-shaped gantry, a multi-layer bowl / cylinder structure gantry, or the like. The gantry 104 can be a rotating gantry that can rotate around a rotation axis or a fixed gantry that cannot move. When the gantry 104 rotates, the imaging source 106 and the detector 107 rotate around the Y axis by any angle, so that a two-dimensional (2D) image of any two-dimensional plane of the target object can be generated.

[0056] The image computer device 102 is communicatively connected to the control device 103 and the detector 107, respectively, and the control device 103 is communicatively connected to the image-guided radiotherapy device 101.

[0057] In some embodiments, the imaging computer device 102 is a computer device with a graphical user interface (GUI), which includes one or more processors, memory, and one or more application programs. For example, the imaging computer device 102 may include an Image Guidance System (IGS) application. The processor of the imaging computer device executes the IGS application to: acquire a current two-dimensional image of the target object taken from a preset angle by the image guidance device in the image-guided radiotherapy apparatus under the current fractionation radiotherapy; then acquire a reference image of the target object under historical fractionation radiotherapy and a first offset corresponding to the reference image; and finally determine the current position offset of the target object under the current fractionation radiotherapy based on the current two-dimensional image of the target object, the reference image, and the first offset.

[0058] In this embodiment of the disclosure, the imaging computer device 102 and the control device 103 can be independent servers, or they can be a server network or server cluster composed of servers. For example, the computer devices described in this embodiment of the disclosure include, but are not limited to, computers, network hosts, single network servers, multiple network server sets, or cloud servers composed of multiple servers. Among them, cloud servers are composed of a large number of computers or network servers based on cloud computing.

[0059] In this embodiment, the imaging computer device 102 and the control device 103 can be general-purpose computer devices or special-purpose computer devices. In specific implementations, the computer device can be a desktop computer, a portable computer, a network server, a handheld computer (Personal Digital Assistant, PDA), a mobile phone, a tablet computer, a wireless terminal device, a communication device, an embedded device, etc. This embodiment does not limit the type of computer device.

[0060] The following is combined with Figure 1 ,by Figure 1 Taking a video computer device as an example, the reset method provided in the embodiments of this disclosure will be described. Figure 2 A flowchart of a reset method provided in this disclosure embodiment is shown below. Figure 2 As shown, the method includes:

[0061] S201, Under the current fractionated radiotherapy, acquire the current two-dimensional image of the target object taken by the image guidance device from a preset angle.

[0062] The image computer device can send a photographing instruction to the control device, and the control device can control the imaging source to emit an imaging beam to obtain a two-dimensional image of the target object at a preset angle on the detector, i.e., a current two-dimensional image of the target object, and the detector can send the current two-dimensional image of the target object to the image computer device.

[0063] In an optional embodiment, the number of preset angles can be 1 or 2.

[0064] It should be noted that when the number of preset angles is 2, the two preset angles are orthogonal to each other. Taking an example in which the preset angles include a first angle and a second angle, the first angle and the second angle are orthogonal to each other. Correspondingly, S201 can be replaced with: under the current fractionated radiotherapy, obtaining a current two-dimensional image of the target object photographed by the image guiding device at the first angle and a current two-dimensional image of the target object photographed by the image guiding device at the second angle.

[0065] In the embodiments of the present disclosure, one of the first angle and the second angle is a horizontal direction corresponding imaging angle (such as a left (L) lateral angle or a right (R) lateral angle), and the two-dimensional image of the target object photographed from the left (L) lateral angle or the right (R) lateral angle is a lateral two-dimensional image of the target object; the other is a vertical direction corresponding imaging angle (such as an anterior (A) frontal angle or a posterior (P) frontal angle), and the two-dimensional image of the target object photographed from the anterior (A) frontal angle or the posterior (P) frontal angle is a frontal two-dimensional image of the target object.

[0066] It should be noted that the horizontal direction can be parallel to the X axis of the IEC coordinate system, and the vertical direction can be parallel to the Y axis of the IEC coordinate system.

[0067] When the number of preset angles is 1, the two-dimensional image of the target object photographed from the preset angle is a lateral two-dimensional image or a frontal two-dimensional image of the target object.

[0068] S202, obtaining a reference image of the target object under historical fractionated radiotherapy and a first offset corresponding to the reference image.

[0069] The reference image is a two-dimensional image of the target object photographed by the image guiding device under the historical fractionated radiotherapy, and the imaging angle of the two-dimensional image is the same as the preset angle.

[0070] The first offset is a position offset of the target object obtained based on the two-dimensional image of the target object photographed by the image guiding device under the historical fractionated radiotherapy. The first offset corresponding to the reference image is used to correct the position of the target object under the historical fractionated radiotherapy, so that the position of the target object after correction under the historical fractionated radiotherapy is consistent with the position of the target object when the treatment plan is formulated.

[0071] The reference image under the historical fractionated radiotherapy can include a reference image taken by the image guidance device under any historical fractionated radiotherapy before the current fractionated radiotherapy. For example, assuming that the current fractionated radiotherapy is the third fractionated radiotherapy, the target object has taken reference images under the second fractionated radiotherapy and the first fractionated radiotherapy, the reference image of the target object under the historical fractionated radiotherapy can be the reference image of the target object under the second fractionated radiotherapy, or the reference image of the target object under the first fractionated radiotherapy.

[0072] Considering that the body state of the target object when taking the reference image of the last fractionated radiotherapy is closest to the body state of the target object under the current fractionated radiotherapy, the effect of resetting the target object under the current fractionated radiotherapy is better by using the reference image of the last fractionated radiotherapy and the first offset corresponding to the reference image. The following is described by taking the reference image of the target object under the historical fractionated radiotherapy as an example. Correspondingly, the first offset is the image guidance result of the reference image of the target object under the last fractionated radiotherapy, which is used to correct the position of the target object identified in the reference image of the target object under the last fractionated radiotherapy, so that the position of the target object identified in the corrected reference image is consistent with the position of the target object identified in the planning image.

[0073] S203, determining a current position offset of the target object under the current fractionated radiotherapy based on the current two-dimensional image of the target object, the reference image, and the first offset.

[0074] The current position offset is used to reset the target object in at least two directions in the current fractionated radiotherapy, so that the position of the target object in at least two directions after resetting is consistent with the position of the target object in at least two directions adjusted based on the first offset under the historical fractionated radiotherapy.

[0075] For example, when the preset angle is the imaging angle corresponding to the horizontal direction, the current position offset can reset the target object in the vertical direction (corresponding to the Z axis of the IEC coordinate system) and the head-to-foot direction (corresponding to the Y axis of the IEC coordinate system). When the preset angle is the imaging angle corresponding to the vertical direction, the current position offset can reset the target object in the horizontal direction (corresponding to the X axis of the IEC coordinate system) and the head-to-foot direction (corresponding to the Y axis of the IEC coordinate system).

[0076] Specifically, the image computer device can determine the current position offset of the target object based on the current two-dimensional image of the target object, the reference image of the target object under the last fractionated radiotherapy, and the first offset corresponding to the reference image under the last fractionated radiotherapy, and send a moving instruction to the control device based on the current position offset. After receiving the moving instruction, the control device can control the treatment bed to move in at least two directions (corresponding to the Y and Z axes of the IEC coordinate system, or the X and Y axes, or the X, Y, and Z axes) to reset the target object, so that the position of the target object in at least two directions after resetting is consistent with the position of the target object corrected based on the first offset under the last fractionated radiotherapy.

[0077] By the above technical solution, only a two-dimensional image of the target object at a preset angle needs to be obtained to obtain the current position offset of the target object under the current fractionated radiotherapy. Compared with CBCT image guidance of the target object, the above technical solution can effectively reduce the time for imaging the target object by using KV-level rays and effectively shorten the time for resetting the target object, thereby achieving the effect of quickly resetting the target object.

[0078] In addition, in this mode, the current position offset of the target object is determined based on the current two-dimensional image of the target object and in combination with the reference image of the target object under the historical fractionated radiotherapy and the first offset corresponding to the reference image, so as to reset the target object. Instead of relying only on the marker line and the laser line of the laser lamp in the radiotherapy device to reset the target object, the present scheme can effectively improve the accuracy of resetting the patient.

[0079] In an optional embodiment, when the image computer device determines the current position offset of the target object under the current fractionated radiotherapy based on the current two-dimensional image of the target object, the reference image, and the first offset, it can be determined by the following two ways.

[0080] The first way is to register the current two-dimensional image of the target object and the reference image to obtain a second offset, and determine the current position offset of the target object under the current fractionated radiotherapy based on the first offset and the second offset.

[0081] Specifically, the current two-dimensional image of the target object and the reference image can be registered based on the position of the target object identified in the current two-dimensional image of the target object and the position of the target object identified in the reference image to obtain a second offset. Then, the sum of the first offset and the second offset can be taken as the current position offset of the target object under the current fractionated radiotherapy.

[0082] The second mode: based on the first offset, the current two-dimensional image of the target object is corrected to obtain a corrected two-dimensional image, and then the corrected two-dimensional image and the reference image are registered to obtain the current position offset of the target object under the current fractionated radiotherapy.

[0083] Specifically, the position of the target object identified in the current two-dimensional image of the target object can be corrected based on the first offset to obtain a corrected two-dimensional image, and then the corrected two-dimensional image and the reference image are registered based on the position of the target object identified in the corrected two-dimensional image and the position of the target object identified in the reference image to obtain the current position offset of the target object under the current fractionated radiotherapy.

[0084] After obtaining the current position offset of the target object by the above two modes, the image computer device can send a moving instruction to the control device based on the current position offset of the target object, and the control device can control the treatment bed to move and reset the target object after receiving the moving instruction, so that the position of the target object after resetting is consistent with the position of the target object corrected based on the first offset under the last fractionated radiotherapy.

[0085] The above content provides two modes for determining the current position offset of the target object under the current fractionated radiotherapy, which can improve the realizability of the embodiments of the present disclosure on the basis of effectively improving the accuracy of resetting the patient.

[0086] In the embodiments of the present disclosure, the image guiding device is not limited, and specifically, the image guiding device can include at least one of a CBCT device, a CT device, and an MR device. The following is described by taking the image guiding device as a CBCT device.

[0087] When the image guiding device is a CBCT device, the current two-dimensional image of the target object obtained in S201 is a two-dimensional projection image. Correspondingly, the reference image of the target object under the historical fractionated radiotherapy can include any one of a target two-dimensional projection image of the target object taken from a preset angle by the CBCT device, and a DRR image obtained by digitally reconstructing the CBCT image. The following will be described in detail by taking (1) the reference image of the target object under the historical fractionated radiotherapy as a target two-dimensional projection image of the target object taken from a preset angle by the CBCT device, and (2) the reference image of the target object under the historical fractionated radiotherapy as a DRR image obtained by digitally reconstructing the CBCT image at a preset angle.

[0088] The CBCT image is a three-dimensional reconstruction image generated by three-dimensional reconstruction of the two-dimensional projection images of the target object taken from different imaging angles by the CBCT device under the historical fractionated radiotherapy.

[0089] (1) The reference image of the target object under the historical fractionated radiotherapy is a target two-dimensional projection image of the target object photographed by the CBCT device from a preset angle.

[0090] On this basis, when obtaining the reference image of the target object under the historical fractionated radiotherapy, the target two-dimensional projection image of the target object photographed by the CBCT device from the preset angle under the historical fractionated radiotherapy can be obtained first, and then the target two-dimensional projection image is taken as the reference image of the target object under the historical fractionated radiotherapy.

[0091] Specifically, the image computer device can obtain a plurality of two-dimensional projection images of the target object photographed by the CBCT device from different imaging angles under the historical fractionated radiotherapy first, then from the plurality of two-dimensional projection images, the two-dimensional projection image with the same imaging angle as the preset angle is taken as the target two-dimensional projection image, and the target two-dimensional projection image is taken as the reference image of the target object under the historical fractionated radiotherapy.

[0092] (2) The reference image of the target object under the historical fractionated radiotherapy is a DRR image obtained by digitally reconstructing the CBCT image at the preset angle.

[0093] On this basis, when obtaining the reference image of the target object under the historical fractionated radiotherapy, the CBCT image of the target object under the historical fractionated radiotherapy can be obtained first, then the CBCT image is digitally reconstructed at the preset angle to obtain a DRR image, and finally the DRR image is taken as the reference image of the target object under the historical fractionated radiotherapy.

[0094] Specifically, the image computer device can obtain a plurality of two-dimensional projection images of the target object photographed by the CBCT device from different imaging angles under the historical fractionated radiotherapy first, then the plurality of two-dimensional projection images are three-dimensionally reconstructed to obtain the CBCT image of the target object under the historical fractionated radiotherapy, and then the CBCT image can be digitally reconstructed at the preset angle to obtain a DRR image, and the DRR image is taken as the reference image of the target object under the historical fractionated radiotherapy.

[0095] In order to more clearly introduce the above-described content, the following will be combined with the above embodiments to describe the reset method provided by the embodiments of the present disclosure, taking the image guide device as the CBCT device, the reference image of the target object under the historical fractionated radiotherapy as the reference image of the target object under the last fractionated radiotherapy, and the number of preset angles as 1 as an example.

[0096] Figure 3 The method flowchart of the reset method provided by the embodiments of the present disclosure is shown in Figure 3 The method comprises:

[0097] S301, under the current fractionated radiotherapy, obtaining a two-dimensional projection image of the target object currently captured by a CBCT device from a preset angle.

[0098] The preset angle can be an L lateral angle or an R lateral angle, and the two-dimensional projection image is an L lateral two-dimensional projection image or an R lateral two-dimensional projection image of the target object. The preset angle can also be an A frontal angle or a P frontal angle, and the two-dimensional projection image is an A frontal two-dimensional projection image or a P frontal two-dimensional projection image of the target object.

[0099] The specific implementation can refer to the description of S201 above, which will not be repeated here.

[0100] S302, obtaining a plurality of two-dimensional projection images of the target object obtained by using a CBCT device from different imaging angles under the last fractionated radiotherapy and a first offset.

[0101] The first offset can be a three-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y, and Z axes, or a six-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y, and Z axes and a rotational offset in X, Y, and Z axes.

[0102] The specific implementation can refer to the description of S202 above, which will not be repeated here.

[0103] S303, from the plurality of two-dimensional projection images, screening a target two-dimensional projection image (i.e., a reference image) with an imaging angle of the preset angle and a corresponding first offset (i.e., a first offset corresponding to the reference image).

[0104] The execution order of S301 in the embodiments of the present disclosure is not limited, for example, S301 can be executed before S302 and S303, or can be executed after S302 and S303, or can be executed simultaneously with S302 and S303.

[0105] S304, registering the two-dimensional projection image of the target object currently and the target two-dimensional projection image to obtain a second offset of the target object.

[0106] In the case that the two-dimensional projection image is an L lateral two-dimensional projection image or an R lateral two-dimensional projection image of the target object, the second offset contains at least two-dimensional offsets, and the two dimensions are offsets of an IEC coordinate system in Y and Z axes.

[0107] In the case that the two-dimensional projection image is an A frontal two-dimensional projection image or a P frontal two-dimensional projection image of the target object, the second offset contains at least two-dimensional offsets, and the two dimensions are offsets of an IEC coordinate system in X and Y axes.

[0108] S305, sum the first offset and the second offset as the current position offset of the target object under the current fractionated radiotherapy.

[0109] The sum of the first offset and the second offset can be the sum of the offsets of the IEC coordinate system in the Y and Z axes, or the sum of the offsets of the IEC coordinate system in the X and Y axes.

[0110] As can be known from the description of S203 above, the present embodiment provides two ways to determine the current position offset of the target object under the current fractionated radiotherapy, therefore, S304-S305 above can be replaced by: correcting the current two-dimensional projection image of the target object based on the first offset to obtain a corrected two-dimensional projection image, and then registering the corrected two-dimensional projection image and the target two-dimensional projection image to obtain the current position offset of the target object under the current fractionated radiotherapy.

[0111] The specific implementation of the above two ways to determine the current position offset of the target object under the current fractionated radiotherapy can refer to the description of S203 above, which will not be repeated here.

[0112] Figure 4 The method flowchart of another reset method provided by the present embodiment is shown in Figure 4 The method comprises:

[0113] S401, under the current fractionated radiotherapy, a two-dimensional projection image of a target object is obtained by a CBCT device from a preset angle.

[0114] The preset angle can be an L lateral angle or an R lateral angle, and the two-dimensional projection image is an L lateral two-dimensional projection image or an R lateral two-dimensional projection image of the target object; the preset angle can also be an A frontal angle or a P frontal angle, and the two-dimensional projection image is an A frontal two-dimensional projection image or a P frontal two-dimensional projection image of the target object.

[0115] The specific implementation can refer to the description of S201 above, which will not be repeated here.

[0116] S402, a CBCT image of the target object and a first offset under the last fractionated radiotherapy are obtained.

[0117] The CBCT image is a three-dimensional reconstruction image generated by three-dimensional reconstruction of two-dimensional projection images of the target object taken by a CBCT device from different imaging angles under the last fractionated radiotherapy; the first offset can be a three-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y and Z axes, or a six-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y and Z axes and a rotational offset in X, Y and Z axes.

[0118] S403, digitally reconstructing the CBCT image at the preset angle to obtain a DRR image at the preset angle.

[0119] The digitally reconstructing the CBCT image at the preset angle to obtain the DRR image at the preset angle can be digitally reconstructing the CBCT image at the preset angle to obtain the DRR image at the preset angle under the current fractionated radiotherapy, or digitally reconstructing the CBCT image at the preset angle to obtain the DRR image at the preset angle under the last fractionated radiotherapy.

[0120] S404, under the current fractionated radiotherapy, registering the current two-dimensional projection image of the target object and the DRR image to obtain a second offset of the target object.

[0121] In the case that the two-dimensional projection image is an L lateral two-dimensional projection image or an R lateral two-dimensional projection image of the target object, the second offset at least includes offsets in two dimensions, which are offsets of an IEC coordinate system in Y and Z axes.

[0122] In the case that the two-dimensional projection image is an A frontal two-dimensional projection image or a P frontal two-dimensional projection image of the target object, the second offset at least includes offsets in two dimensions, which are offsets of an IEC coordinate system in X and Y axes.

[0123] S405, summing the first offset and the second offset as a current position offset of the target object under the current fractionated radiotherapy.

[0124] The sum of the first offset and the second offset can be a sum of offsets of an IEC coordinate system in Y and Z axes, or a sum of offsets of an IEC coordinate system in X and Y axes.

[0125] As can be known from the description of S203, the present embodiment provides two ways to determine the current position offset of the target object under the current fractionated radiotherapy. Therefore, S404-S405 can be replaced by: correcting the current two-dimensional projection image of the target object based on the first offset to obtain a corrected two-dimensional projection image, and then registering the corrected two-dimensional projection image and the DRR image to obtain the current position offset of the target object under the current fractionated radiotherapy.

[0126] The resetting method provided by the present embodiment is mainly described from the perspective that the number of preset angles is 1. Next, taking the image guiding device as a CBCT device, the reference image of the target object under the historical fractionated radiotherapy as the reference image of the target object under the most recent fractionated radiotherapy, the number of preset angles as 2, and the first angle as a lateral angle (L or R lateral) and the second angle as a frontal angle (A or P frontal) as examples, the resetting method provided by the present embodiment is described.

[0127] Figure 5 The method flowchart of another resetting method provided by the present embodiment is shown in FIG. 5, and the method includes the following steps. Figure 5

[0128] S501, under the current fractionated radiotherapy, acquiring the current two-dimensional projection images of the target object taken by the CBCT device from the lateral angle and the frontal angle respectively.

[0129] The current two-dimensional projection images include a lateral two-dimensional projection image and a frontal two-dimensional projection image of the target object.

[0130] S502, acquiring the first offset and the plurality of two-dimensional projection images of the target object taken by the CBCT device from different imaging angles under the most recent fractionated radiotherapy.

[0131] The first offset can be a three-dimensional offset, such as the horizontal offset of the IEC coordinate system in the X, Y and Z axes, or a six-dimensional offset, such as the horizontal offset of the IEC coordinate system in the X, Y and Z axes and the rotational offset in the X, Y and Z axes.

[0132] S503, under the current fractionated radiotherapy, selecting target two-dimensional projection images with the same imaging angle as the lateral angle and the frontal angle from the plurality of two-dimensional projection images.

[0133] The target two-dimensional projection image with the same imaging angle as the lateral angle is a lateral target two-dimensional image, and the target two-dimensional projection image with the same imaging angle as the frontal angle is a frontal target two-dimensional image.

[0134] ​The embodiments of the present disclosure do not limit the execution sequence of S501. For example, S501 can be executed before S502 and S503, can be executed after S502 and S503, or can be executed simultaneously with S502 and S503.

[0135] S504, under the current fractionated radiotherapy, registering (two-dimensional registration) the lateral two-dimensional projection image and the lateral target two-dimensional image to obtain a lateral two-dimensional offset; registering (two-dimensional registration) the frontal two-dimensional projection image and the frontal target two-dimensional image to obtain a frontal two-dimensional offset; and obtaining a second offset of the target object based on the lateral two-dimensional offset and the frontal two-dimensional offset.

[0136] The lateral two-dimensional offset can be an offset of the IEC coordinate system in two directions of Y and Z axes; the frontal two-dimensional offset can be an offset of the IEC coordinate system in two directions of X and Y axes; and the second offset can be a three-dimensional offset, such as a horizontal offset of the IEC coordinate system in three directions of X, Y and Z axes, or a six-dimensional offset, such as a horizontal offset of the IEC coordinate system in three directions of X, Y and Z axes and a rotational offset in three directions of X, Y and Z axes.

[0137] S505, summing the first offset and the second offset as a current position offset of the target object under the current fractionated radiotherapy.

[0138] As can be known from the description of S203, the embodiments of the present disclosure provide two ways to determine the current position offset of the target object under the current fractionated radiotherapy. Therefore, S504-S505 can be replaced by: based on the first offset, respectively correcting the lateral two-dimensional projection image and the frontal two-dimensional projection image of the target object of the target object to obtain corrected lateral two-dimensional projection image and frontal two-dimensional projection image, then registering (two-dimensional registration) the corrected lateral two-dimensional projection image and the lateral target two-dimensional image to obtain a corrected lateral two-dimensional offset, and registering (two-dimensional registration) the corrected frontal two-dimensional projection image and the frontal target two-dimensional image to obtain a corrected frontal two-dimensional offset; and obtaining a second offset of the target object based on the corrected lateral two-dimensional offset and the corrected frontal two-dimensional offset.

[0139] Figure 6 The method flowchart of another resetting method provided by the embodiments of the present disclosure is shown in FIG. 6, which includes the following steps. Figure 6

[0140] S601, under the current fractionated radiotherapy, acquiring a two-dimensional lateral projection image and a two-dimensional frontal projection image of the target object currently taken by a CBCT device from a L lateral angle and an A frontal angle, respectively.

[0141] ​S602, acquire a CBCT image of the target object and a first offset under a last fractionated radiotherapy.

[0142] The CBCT image is a three-dimensional reconstruction image generated by three-dimensional reconstruction of two-dimensional projection images of the target object taken from different imaging angles by the CBCT device under the last fractionated radiotherapy; the first offset is a result of CBCT image guidance, and the first offset can be a three-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y and Z axes, or a six-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y and Z axes and a rotational offset in X, Y and Z axes.

[0143] S603, digitally reconstruct the CBCT image at the L lateral angle and the A frontal angle to obtain a lateral DRR image and a frontal DRR image at the L lateral angle and the A frontal angle in a repositioning treatment stage under the current fractionated radiotherapy.

[0144] S604, register the current lateral two-dimensional projection image and the current frontal two-dimensional projection image of the target object with the lateral DRR image and the frontal DRR image respectively to obtain a second offset of the target object under the current fractionated radiotherapy.

[0145] The second offset can be a three-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y and Z axes, or a six-dimensional offset, such as a horizontal offset of an IEC coordinate system in X, Y and Z axes and a rotational offset in X, Y and Z axes.

[0146] S605, sum the first offset and the second offset as a current position offset of the target object under the current fractionated radiotherapy.

[0147] The sum of the first offset and the second offset can be a sum of horizontal offsets and / or rotational offsets of an IEC coordinate system in X, Y and Z axes.

[0148] As can be known from the description of S203 above, the embodiments of the present disclosure provide two ways to determine the current position offset of the target object under the current fractionated radiotherapy, and therefore, S604-S605 above can be replaced by: correcting the current lateral two-dimensional projection image and the current frontal two-dimensional projection image of the target object based on the first offset to obtain corrected lateral two-dimensional projection image and frontal two-dimensional projection image, and then registering the corrected lateral projection image and the frontal two-dimensional projection image with the DRR lateral image and the DRR frontal image respectively to obtain the current position offset of the target object under the current fractionated radiotherapy.

[0149] In an optional implementation, the image computer device can further store the current two-dimensional image of the target object and the current position offset of the target object under the current fractionated radiotherapy, so that the stored current two-dimensional image of the target object under the current fractionated radiotherapy can be used as a reference image of a next fractionated radiotherapy of the current fractionated radiotherapy, and the stored current position offset of the target object under the current fractionated radiotherapy can be used as a first offset of the next fractionated radiotherapy of the current fractionated radiotherapy.

[0150] The following takes the radiotherapy process of a target object including N (N is a natural number greater than 1) fractionated radiotherapies as an example to introduce a resetting method provided by the embodiments of the present disclosure, as shown in the following figure, the method includes: Figure 7

[0151] S701, in a resetting treatment stage under the nth fractionated radiotherapy, first, a current two-dimensional projection image of the target object is obtained by the CBCT device from a preset angle; then, a reference image of the target object under the mth fractionated radiotherapy (indicating a historical fractionated radiotherapy) and a first offset corresponding to the reference image are obtained; finally, based on the current two-dimensional image of the target object, the reference image and the first offset, a current position offset of the target object under the nth fractionated radiotherapy is determined.

[0152] Wherein, n is an integer greater than 1, and m is an integer greater than 0 and less than n.

[0153] In the case of m equal to 1, the reference image of the target object under the first fractionated radiotherapy and the first offset corresponding to the reference image can be obtained in the following way:

[0154] Method one: (1) obtaining a target two-dimensional projection image of the target object under the first fractionated radiotherapy by the CBCT device from a preset angle; (2) taking the target two-dimensional projection image as the reference image of the target object under the first fractionated radiotherapy. On this basis, the first offset corresponding to the reference image of the target object under the first fractionated radiotherapy is the offset obtained after registering the target two-dimensional projection image and a DRR image of the preset angle generated based on the planning image of the target object.

[0155] Method two: (1) obtaining a plurality of two-dimensional projection images of the target object under the first fractionated radiotherapy by the CBCT device from different imaging angles; (2) from the plurality of two-dimensional projection images, taking a two-dimensional projection image with the same imaging angle as the preset angle as the target two-dimensional projection image; (3) taking the target two-dimensional projection image as the reference image of the target object under the first fractionated radiotherapy.

[0156] ​On this basis, the first offset corresponding to the reference image of the target object under the first fractionated radiotherapy is the offset obtained after registration of the two-dimensional projection image of the target object and the DRR image at the preset angle generated based on the planning image of the target object. Alternatively, the first offset corresponding to the reference image of the target object under the first fractionated radiotherapy is the offset obtained after registration of the three-dimensional reconstruction image generated after three-dimensional reconstruction of the plurality of two-dimensional projection images of the target object obtained by the CBCT device from different imaging angles and the planning image of the target object.

[0157] Method three: (1) obtaining a CBCT image of the target object under the first fractionated radiotherapy, wherein the CBCT image is a three-dimensional reconstruction image generated after three-dimensional reconstruction of the two-dimensional projection images of the target object obtained by the CBCT device from different imaging angles (such as an imaging angle range greater than 180 degrees) under the first fractionated radiotherapy; (2) digitally reconstructing the CBCT image at a preset angle to obtain a DRR image; and (3) taking the DRR image as the reference image of the target object under the first fractionated radiotherapy. On this basis, the first offset corresponding to the reference image of the target object under the first fractionated radiotherapy is the offset obtained after registration of the CBCT image of the target object and the planning image of the target object.

[0158] The planning image can be one or more of a CT image, an MR image, or other three-dimensional images used to develop a treatment plan for the target object.

[0159] In the case where m is greater than 1, the reference image of the target object under the mth fractionated radiotherapy and the first offset corresponding to the reference image can be obtained by the following methods:

[0160] Method one: (1) obtaining a target two-dimensional projection image of the target object obtained by the CBCT device from a preset angle under the mth fractionated radiotherapy (i.e., the previous fractionated radiotherapy of the current fractionated radiotherapy); and (2) taking the target two-dimensional projection image as the reference image of the target object under the n-1th fractionated radiotherapy. On this basis, the current position offset of the target object under the n-1th fractionated radiotherapy is taken as the first offset corresponding to the reference image.

[0161] Method two: (1) obtaining a plurality of two-dimensional projection images of the target object obtained by the CBCT device from different imaging angles under any historical fractionated radiotherapy in the mth fractionated radiotherapy (m = 1, 2, 3, …, n-1); (2) from the plurality of two-dimensional projection images, taking a two-dimensional projection image with the same imaging angle as the preset angle as a target two-dimensional projection image; and (3) taking the target two-dimensional projection image as the reference image of the target object under the n-1th fractionated radiotherapy.

[0162] On this basis, the first offset corresponding to the reference image of the target object under the mth fraction of radiotherapy is: the offset obtained after registration of the two-dimensional projection image of the target and the DRR image at a preset angle generated based on the planning image of the target object. Alternatively, the first offset corresponding to the reference image of the target object under the mth fraction of radiotherapy is: the offset obtained after registration of the three-dimensional reconstruction image generated after three-dimensional reconstruction of the plurality of two-dimensional projection images of the target object obtained by the CBCT device from different imaging angles under the mth fraction of radiotherapy and the planning image of the target object.

[0163] Method three: (1) acquiring a CBCT image of the target object under any historical fraction of radiotherapy in the mth fraction of radiotherapy m = 1, 2, 3, … n-1, wherein the CBCT image is a three-dimensional reconstruction image generated after three-dimensional reconstruction of the two-dimensional projection image of the target object obtained by the CBCT device from different imaging angles (such as the entire imaging angle range being greater than 180 degrees) under any historical fraction of radiotherapy in the mth fraction of radiotherapy m = 1, 2, 3, … n-1; (2) digitally reconstructing the CBCT image at a preset angle to obtain a DRR image; (3) taking the DRR image as the reference image of the target object under any historical fraction of radiotherapy in the mth fraction of radiotherapy m = 1, 2, 3, … n-1. On this basis, the first offset corresponding to the reference image of the target object under the mth fraction of radiotherapy is: the offset obtained after registration of the CBCT image of the target object and the planning image of the target object.

[0164] S702, n = n + 1, determining whether n is greater than N, if not, executing S701; if yes, ending the flow.

[0165] The ending of the flow indicates that all fractions of radiotherapy are completed.

[0166] Figure 8 A schematic block diagram of an example electronic device 800 that can be used to implement embodiments of the present disclosure is shown. The electronic device is intended to represent various forms of digital computers, such as laptops, desktops, tablets, personal digital assistants, servers, blade servers, mainframes, and other appropriate computers. The electronic device can also represent various forms of mobile devices, such as personal digital assistants, cellular telephones, smartphones, wearable devices, and other similar computing devices. The components shown here, their connections and relationships, and their functions, are meant to be examples only, and are not meant to limit the implementations of the present disclosure described and / or claimed in this document. In some embodiments, the electronic device can be the image computer device shown in Figure 1 FIG. 1.

[0167] As Figure 8As shown, the electronic device 800 includes a computing unit 801 that can perform various appropriate actions and processes in accordance with a computer program stored in a read-only memory 802 or a computer program loaded into a random access memory 803 from a storage unit 808. Various programs and data required for the operation of the electronic device 800 can also be stored in the random access memory (RAM) 803. The computing unit 801, the read-only memory (ROM) 802, and the RAM 803 are connected to each other through a bus 804. An input / output (I / O) interface 805 is also connected to the bus 804.

[0168] A plurality of components in the electronic device 800 are connected to the input / output interface 805, including an input unit 806 such as a keyboard, a mouse, and the like, an output unit 807 such as various types of displays, a speaker, and the like, a storage unit 808 such as a magnetic disk, an optical disk, and the like, and a communication unit 809 such as a network card, a modem, a wireless communication transceiver, and the like. The communication unit 809 allows the electronic device 800 to exchange information / data with other devices through a computer network such as the Internet and / or various telecommunication networks.

[0169] The computing unit 801 can be various general-purpose and / or special-purpose processing components having processing and computing capabilities. Some examples of the computing unit 801 include, but are not limited to, a central processing unit, a graphics processing unit (GPU), various specialized artificial intelligence (AI) computing chips, various computing units running machine learning model algorithms, a digital signal processor, and any appropriate processor, controller, microcontroller, and the like. The computing unit 801 performs various methods and processes described above, such as the reset method. For example, in an embodiment, the reset method can be implemented as a computer software program that is tangibly embodied in a machine-readable medium, such as the storage unit 808. In an embodiment, part or all of the computer program can be loaded and / or installed on the electronic device 800 via the ROM 702 and / or the communication unit 809. When the computer program is loaded into the RAM 803 and executed by the computing unit 801, one or more steps of the reset method described above can be performed. Alternatively, in other embodiments, the computing unit 801 can be configured to perform the reset method by any other appropriate means, such as by means of firmware.

[0170] The various embodiments of the systems and techniques described above can be implemented in digital electronic circuitry, integrated circuitry, specially designed application specific integrated circuits (ASICs), field programmable gate arrays (FPGAs) computer hardware, firmware, software, and / or combinations of each to perform the various embodiments. These various embodiments can include implementation in one or more computer programs that are executable and / or interpretable on a programmable system including at least one programmable processor, which can be special or general purpose, coupled to receive data and instructions from, and to transmit data and instructions to, a storage system, at least one input device, and at least one output device.

[0171] Program code for carrying out methods of the present disclosure can be written in any combination of one or more programming languages. The program code can be provided to a processor or controller of a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the program code, when executed by the processor or controller, produces a means for implementing the functions / operations specified in the flowchart and / or block diagram block or blocks. The program code can be executed entirely on a machine, partially on a machine, partially on a machine as a stand-alone software package, and partially on a remote machine or entirely on a remote machine or server.

[0172] In the context of the present disclosure, a machine-readable medium can be a tangible medium that contains or stores a program for use by or in connection with an instruction execution system, apparatus, or device. The machine-readable medium can be a machine-readable signal medium or a machine-readable storage medium. A machine-readable medium can include but is not limited to an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any suitable combination of the foregoing. More specific examples of the machine-readable storage medium will include one or more lines of electrical connections, portable computer disks, hard disk drives, random access memory, read-only memory, erasable programmable read-only memory, optical fibers, portable compact disc read-only memories, optical storage devices, magnetic storage devices, or any suitable combination of the foregoing.

[0173] To provide for interaction with a user, the systems and techniques described here can be implemented on a computer having a display device (e.g., a cathode ray tube (CRT) or liquid crystal display (LCD) monitor) for displaying information to the user and a keyboard and a pointing device (e.g., a mouse or a trackball) by which the user can provide input to the computer. Other kinds of devices can be used to provide for interaction with a user as well; for example, feedback provided to the user can be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and input from the user can be received in any form, including acoustic, speech, or tactile input.

[0174] The systems and techniques described here can be implemented in a computing system that includes a back end component (e.g., as a data server), or that includes a middleware component (e.g., an application server), or that includes a front end component (e.g., a user computer having a graphical user interface or a Web browser through which a user can interact with an implementation of the systems and techniques described here), or any combination of such back end, middleware, or front end components. The components of the system can be interconnected by any form or medium of digital data communication (e.g., a communication network). Examples of communication networks include a local area network (LAN), a wide area network (WAN), and the Internet.

[0175] The computer system can include clients and servers. A client and server are generally remote from each other and typically interact through a communication network. The relationship of client and server can arise by virtue of computer programs running on the respective computers and having a client-server relationship to each other. The server can be a cloud server, a server of a distributed system, or a server combined with a blockchain.

[0176] It should be understood that the various forms of flow shown above can be re-ordered, added to, or deleted from without departing from the scope of the present disclosure. For example, the steps recited in the present disclosure can be executed in parallel, in series, or in a different order, as long as the desired results of the present disclosure are achieved, and the present disclosure is not limited herein.

[0177] The above detailed description does not limit the scope of the disclosure. Various modifications, combinations, sub-combinations and alternatives can be made to the detailed description. Any modification, equivalent replacement and improvement etc. made within the spirit and principle of the disclosure shall be included in the scope of the disclosure.

Claims

1. A reset method, characterized by, The method comprises: under current fractionated radiotherapy, acquiring a current two-dimensional image of a target object photographed from a preset angle by an image guiding device; acquiring a reference image of the target object under historical fractionated radiotherapy and a first offset corresponding to the reference image; the reference image is a two-dimensional image of the target object photographed by the image guiding device under the historical fractionated radiotherapy, and the imaging angle of the two-dimensional image is the same as the preset angle; the first offset is a position offset of the target object based on a two-dimensional image of the target object photographed by the image guiding device under the historical fractionated radiotherapy; based on the current two-dimensional image of the target object, the reference image and the first offset, determining a current position offset of the target object under the current fractionated radiotherapy; the current position offset is used for resetting the target object in at least two directions under the current fractionated radiotherapy, so that the position of the target object in the at least two directions after resetting is consistent with the position of the target object in the at least two directions adjusted based on the first offset under the historical fractionated radiotherapy.

2. The method of claim 1, wherein, The method comprises: registering the current two-dimensional image of the target object and the reference image to obtain a second offset of the target object; the sum of the first offset and the second offset is taken as the current position offset of the target object under the current fractionated radiotherapy.

3. The method of claim 1, wherein, The method comprises: based on the first offset, correcting the current two-dimensional image of the target object to obtain a corrected two-dimensional image; registering the corrected two-dimensional image and the reference image to obtain the current position offset of the target object under the current fractionated radiotherapy.

4. The method of claim 1, wherein, In the case that the preset angle comprises two angles of a first angle and a second angle, the first angle and the second angle are orthogonal to each other; in the case that the preset angle comprises one angle, the current two-dimensional image of the target object photographed from the preset angle is a lateral two-dimensional image or an anteroposterior two-dimensional image of the target object.

5. The method of claim 1, wherein, The image guiding device comprises at least one of a cone beam computed tomography (CBCT) device, a CT device and a magnetic resonance (MR) device.

6. The method of claim 5, wherein, The image guiding device is a CBCT device, and the current two-dimensional image of the target object is a two-dimensional projection image; The method comprises: acquiring a target two-dimensional projection image of the target object photographed from the preset angle by the CBCT device under the historical fractionated radiotherapy; taking the target two-dimensional projection image as the reference image of the target object under the historical fractionated radiotherapy.

7. The method of claim 6, wherein, The target two-dimensional projection image of the target object is obtained from the preset angle by using the CBCT device under the historical fractionated radiotherapy, and the obtaining includes: A plurality of two-dimensional projection images of the target object are obtained from different imaging angles by using the CBCT device under the historical fractionated radiotherapy; From the plurality of two-dimensional projection images, a two-dimensional projection image with the same imaging angle as the preset angle is selected as the target two-dimensional projection image.

8. The method of claim 5, wherein, The image guiding device is a CBCT device, and the current two-dimensional image of the target object is a two-dimensional projection image; The reference image of the target object under the historical fractionated radiotherapy includes: A CBCT image of the target object under the historical fractionated radiotherapy is obtained; the CBCT image is a three-dimensional reconstruction image generated by performing three-dimensional reconstruction on two-dimensional projection images of the target object taken from different imaging angles by the CBCT device under the historical fractionated radiotherapy; A digital reconstruction image DRR image is obtained by performing digital reconstruction on the CBCT image at the preset angle; The DRR image is used as the reference image of the target object under the historical fractionated radiotherapy.

9. The method of claim 1, wherein, The method further includes: The current two-dimensional image of the target object and the current position offset of the target object under the current fractionated radiotherapy are stored to be used as the reference image of the target object under the historical fractionated radiotherapy and the first offset corresponding to the reference image in the next fractionated radiotherapy, respectively.

10. The method of claim 1, wherein, The reference image of the target object under the historical fractionated radiotherapy is the reference image of the target object under the most recent historical fractionated radiotherapy.

11. An electronic device, comprising: The electronic device includes: A processor; A memory configured to store executable instructions of the processor; The processor is configured to execute the instructions to implement the reset method according to any one of claims 1-10.

Images