Microwave-responsive antibacterial-promoting-repairing bismuth telluride-based thermoelectric material, preparation and application thereof

The microwave-responsive zinc oxide-bismuth telluride thermoelectric material solves the problem of biofilm clearance and tissue repair in wound infection, achieving efficient antibacterial and continuous repair, and overcoming the shortcomings of traditional thermoelectric materials and the poor penetration ability of photothermal therapy.

CN121337986BActive Publication Date: 2026-05-29XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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Patent Information

Application Number
CN202511916503.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-12-18
Publication Date
2026-05-29
Estimated Expiration
2045-12-18

AI Technical Summary

Technical Problem

Existing thermoelectric materials are difficult to simultaneously remove biofilms and continuously promote tissue repair in the treatment of wound infections. Traditional antibiotic treatment cannot completely eradicate biofilms, photothermal therapy has insufficient penetration ability, and thermoelectric materials have low energy conversion efficiency, making it difficult to achieve effective antibacterial and continuous repair.

Method used

A microwave-responsive bismuth telluride-based thermoelectric material was developed. Through a zinc oxide-bismuth telluride (ZnO-Bi2Te3) composite material, a large amount of ROS is generated by microwave excitation for efficient antibacterial activity. The material also promotes tissue repair through thermoelectric effects and slow release of zinc ions. At the same time, microneedle patches are used to precisely locate lesions.

Benefits of technology

It achieves efficient removal of biofilm, avoids infection recurrence, continuously promotes tissue repair, provides personalized treatment plans, reduces damage to normal tissues, and has the potential for large-scale production.

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Abstract

The present application relates to a kind of microwave response antibacterial promotes the repair of bismuth telluride-based thermoelectric material and preparation and application, belong to biological medicine technical field.The microwave response antibacterial promotes the repair of bismuth telluride-based thermoelectric material includes zinc oxide-bismuth telluride.The preparation method of the microwave response antibacterial promotes the repair of bismuth telluride-based thermoelectric material, including the following steps: bismuth nitrate pentahydrate and polyvinylpyrrolidone are dissolved in ethylene glycol to obtain solution A;Sodium hydroxide and sodium tellurite are dissolved in ethylene glycol to obtain solution B;Zinc oxide is dissolved in ethylene glycol to obtain solution C;Solution A, solution B and solution C are mixed, and the mixed solution is heated, and reaction product is prepared by reaction;The reaction product is treated, and zinc oxide-bismuth telluride is prepared.The microwave response antibacterial promotes the repair of bismuth telluride-based thermoelectric material provided by the present application can not only avoid the related risk of antibiotic treatment when being used for wound infection treatment, but also effectively remove bacterial film and continuously promote wound repair.
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Citation Information

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