Composition for improving sticky and greasy skin feeling of high-concentration glass color and preparation method thereof

Abstract

The invention relates to the technical field of cosmetics, in particular to a composition for improving the sticky and greasy skin feeling of high-concentration glass color and a preparation method thereof.The composition is prepared from, by weight, 2-4 parts of glyceryl polyether surfactant, 0.1-1 part of amino acid derivative surfactant, 0.5-6 parts of hydrophilic siloxane derivative and 0.1-3.5 parts of microemulsion phase; the microemulsion phase is prepared from polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, non-polar hydrocarbon grease, aliphatic dihydric alcohol and water. According to the composition, through the synergistic effect of the glyceryl polyether surfactant, the amino acid derivative surfactant, the hydrophilic siloxane derivative and the microemulsion phase, the sticky and greasy skin feeling of high-concentration glass color due to the formula is remarkably improved, the smearing freshness and consumer acceptance are improved, the formula process is simple, and industrial production is easy.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a composition and its preparation method for improving the sticky feel of high-concentration Pro-Xylane. Background Technology

[0002] Pro-Xylane (hydroxypropyl tetrahydropyranotriol), a star anti-aging ingredient, is widely used in skincare products due to its excellent ability to promote collagen synthesis. However, high-concentration Pro-Xylane (≥10%) formulations often result in a sticky, heavy feel, affecting user experience, especially in summer or for people with oily skin. This stickiness mainly stems from the hydrogen bonding between Pro-Xylane molecules and its high hydrophilicity, leading to a thick texture and poor absorption of the formula.

[0003] Traditional solutions include adding volatile silicone oils or reducing the concentration of Pro-Xylane, but the former may cause skin irritation, while the latter weakens efficacy. In existing technologies, glycerol polyethers and silane derivatives are often used to adjust formulation viscosity, but their effects as single ingredients are limited. For example, Chinese invention patent application CN118319777A discloses a supramolecular Pro-Xylane composition with multi-target anti-aging effects on the skin and its preparation method. It achieves the penetration-enhancing effect of Pro-Xylane by linking two delivery solvents, organic acids and amino acids, into a stable and ordered mixture through hydrogen bonds, but the effect is limited. Summary of the Invention

[0004] To address the problems in the prior art, the first aspect of this invention provides a composition for improving the sticky feel of high-concentration BOXOR on the skin, wherein the raw materials for preparation, by weight, include: 2-4 parts of glycerol polyether surfactant 0.1-1 part of amino acid derivative surfactants 0.5-6 parts of hydrophilic siloxane derivatives Microemulsion phase: 0.1-3.5 parts; The microemulsion phase comprises polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, nonpolar hydrocarbon oils, aliphatic diols, and water.

[0005] In one embodiment, the mass ratio of the glycerol polyether surfactant, the amino acid derivative surfactant, the hydrophilic siloxane derivative, and the microemulsion phase is (2-3):(0.2-0.5):(2-5):(1.5-3.5).

[0006] In a preferred embodiment, the mass ratio of the glycerol polyether surfactant, the amino acid derivative surfactant, the hydrophilic siloxane derivative, and the microemulsion phase is 2:0.2:3:2.4.

[0007] This invention utilizes a specific composition—glycerol polyether surfactants, amino acid derivative surfactants, hydrophilic siloxane derivatives, and a microemulsion phase—to synergistically improve the sticky feel of high-concentration Pro-Xylane formulations while maintaining stability and efficacy. The effect is particularly pronounced when the mass ratio of glycerol polyether surfactants, amino acid derivative surfactants, hydrophilic siloxane derivatives, and the microemulsion phase is (2-3):(0.2-0.5):(2-5):(1.5-3.5). At this ratio, the glycerol polyether surfactants first bind to Pro-Xylane through hydrogen bonds, forming a molecular encapsulation layer and reducing direct contact with the skin. The siloxane segments of the hydrophilic siloxane derivatives interact with the hydrophobic regions of the skin surface, significantly reducing interfacial tension and providing a foundation for the rapid and uniform spread of subsequent formulations on the skin. The amino acid derivative surfactants accelerate Pro-Xylane penetration and, together with the nano-dispersion system of the microemulsion phase, uniformly deliver Pro-Xylane to the stratum corneum, avoiding the heaviness and stickiness caused by localized accumulation of Pro-Xylane on the skin surface.

[0008] In one embodiment, the glycerol polyether surfactant includes at least one of glycerol polyether-26, PEG-10 glycerol isostearate, and PEG-7 glycerol cocoate.

[0009] In a preferred embodiment, the glycerol polyether surfactant includes glycerol polyether-26.

[0010] In one embodiment, the amino acid derivative surfactant includes at least one of sodium bis(lauramide-glutamine)lysine, sodium lauroyl sarcosine, and sodium stearoyl glutamate.

[0011] In a preferred embodiment, the amino acid derivative surfactant includes sodium di(lauramide-glutamine)lysine.

[0012] In one embodiment, the hydrophilic siloxane derivative includes at least one of bis-PEG-18 methyl ether dimethylsilane, PEG / PPG-18 / 18 polydimethylsiloxane, and PEG-7 methyl ether polydimethylsiloxane.

[0013] In a preferred embodiment, the hydrophilic siloxane derivative comprises bis-PEG-18 methyl ether dimethylsilane.

[0014] In one embodiment, the mass ratio of the polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, nonpolar hydrocarbon oils, aliphatic diols and water is (0.2-0.8):(0.02-0.08):(0.2-0.8):(0.1-0.6):(0.1-0.6):(0.2-0.6):(0.1-0.3).

[0015] In a preferred embodiment, the mass ratio of the polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, nonpolar hydrocarbon oils, aliphatic diols and water is (0.3-0.6):(0.03-0.06):(0.4-0.6):(0.1-0.4):(0.1-0.4):(0.4-0.6):(0.2-0.3).

[0016] In a more preferred embodiment, the mass ratio of the polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, nonpolar hydrocarbon oils, aliphatic diols and water is 0.50:0.05:0.60:0.20:0.20:0.6:0.25.

[0017] In one embodiment, the polyoxyethylene hydrogenated castor oil includes PEG-60 hydrogenated castor oil.

[0018] In one embodiment, the nonpolar hydrocarbon oil includes at least one of hydrogenated polydecene, squalane, and hydrogenated polyisobutylene.

[0019] In one embodiment, the aliphatic diol includes at least one of 1,3-butanediol, 1,3-propanediol, dipropylene glycol, and propylene glycol.

[0020] In a preferred embodiment, the aliphatic diol comprises 1,3-butanediol.

[0021] A second aspect of the present invention provides a method for preparing a composition that improves the sticky feel of high-concentration phenolic resin, comprising at least the following steps: The glycerol polyether surfactant, amino acid derivative surfactant, hydrophilic siloxane derivative and microemulsion phase were stirred and mixed evenly at 40-50°C to obtain the composition that improves the sticky feel of high concentration of Bosein.

[0022] In one embodiment, the method for preparing the microemulsion phase includes: S1. Mix polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate and aliphatic diol, and heat in a water bath to 60-70°C to obtain phase A; S2. Mix isostearyl alcohol, isostearic acid, and nonpolar hydrocarbon oils, and heat in a water bath to 60-70°C to obtain phase B; S3. Under stirring conditions, slowly add phase B dropwise to phase A, and continue stirring for 10-15 minutes to obtain a mixed phase; S4. Water is slowly added dropwise to the mixed phase and stirred until homogeneous to obtain the microemulsion phase.

[0023] Beneficial effects 1. The composition of the present invention significantly improves the sticky feel of high-concentration Pro-Xylane formulations through the synergistic effect of glycerol polyether surfactants, amino acid derivative surfactants, hydrophilic siloxane derivatives, and a microemulsion phase. Glycerol polyether surfactants encapsulate Pro-Xylane through hydrogen bonds, reducing its direct contact with the skin; hydrophilic siloxane derivatives reduce interfacial tension, promoting uniform spread of the formulation on the skin; amino acid derivative surfactants accelerate Pro-Xylane penetration and, together with the nano-dispersion system of the microemulsion phase, prevent localized accumulation of Pro-Xylane on the skin surface, thereby eliminating the feeling of heaviness and stickiness.

[0024] 2. Traditional solutions require reducing the concentration of Pro-Xylane to ≤5% to improve skin feel, while this invention achieves 100% skin feel satisfaction even at a high concentration of 15%, thus achieving compatibility between high concentration of Pro-Xylane (≥15%) and a refreshing skin feel.

[0025] 3. The composition of the present invention has a simple preparation method, few operation steps, readily available raw materials, mild reaction conditions, is suitable for large-scale production, and has significant prospects for industrial application. Attached Figure Description

[0026] Figure 1 The figures show the visual results of the stickiness of the samples prepared in each embodiment and comparative example; a and m in the figures are the visual results of the stickiness of the samples prepared in Examples 1-2 and Comparative Examples 1-11, respectively. Detailed Implementation

[0027] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to embodiments and accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. Experimental methods not specifying specific conditions in the embodiments were performed under conventional conditions or conditions recommended by the manufacturer. Reagents not specifying manufacturers are all commercially available conventional products.

[0028] The sample information used in this application is as follows: The glycerol polyether-26 is designated LIPONIC EG-1 and is sourced from Clariant Chemicals (Shanghai) Co., Ltd.

[0029] The sodium di(lauramide-glutamine)lysine is designated Pellicer LB-10 and is sourced from ASAHIKASEI FINECHEM CO., LTD.

[0030] The bis-PEG-18 methyl ether dimethylsilane is designated DOWSIL 2511 Cosmetic Wax and is sourced from Dow (Zhangjiagang) Investment Co., Ltd.

[0031] The hydrogenated polydecene is designated Silkflo 364 and is sourced from INEOSCO FELUY.

[0032] Example 1 The first aspect of this example provides a composition for improving the sticky feel of high-concentration BOXOR on the skin, wherein the raw materials for preparation are, by weight: Glyceryl polyether-26 2 parts 0.2 parts of sodium bis(lauramide-glutamine)lysine 3 parts of bis-PEG-18 methyl ether dimethylsilane 2.4 parts of microemulsion phase; The microemulsion phase comprises PEG-60 hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, nonpolar hydrocarbon oils, butanediol, and water.

[0033] The mass ratio of the PEG-60 hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, nonpolar hydrocarbon oils, 1,3-butanediol, and water is 0.50:0.05:0.60:0.20:0.20:0.6:0.25.

[0034] The nonpolar hydrocarbon oil is hydrogenated polydecene.

[0035] The second aspect of this example provides a method for preparing a composition that improves the sticky feel of high-concentration BOXOR on the skin, comprising the following steps: The glycerol polyether surfactant, amino acid derivative surfactant, hydrophilic siloxane derivative and microemulsion phase were stirred and mixed evenly at 45°C to obtain the composition that improves the sticky feel of high concentration of Bosein.

[0036] The method for preparing the microemulsion phase includes: S1. Polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate and aliphatic diol are mixed and heated in a water bath to 65°C to obtain phase A; S2. Mix isostearyl alcohol, isostearic acid, and nonpolar hydrocarbon oils, and heat in a water bath to 65°C to obtain phase B; S3. Under stirring conditions, phase B is slowly added dropwise to phase A, and stirring is continued for 12 minutes to obtain a mixed phase; S4. Water is slowly added dropwise to the mixed phase and stirred until homogeneous to obtain the microemulsion phase.

[0037] Example 2 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 4 parts 0.4 parts of sodium bis(lauramide-glutamine)lysine 6 parts of bis-PEG-18 methyl ether dimethylsilane 2.4 parts of microemulsion phase.

[0038] Comparative Example 1 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: 0.2 parts of sodium bis(lauramide-glutamine)lysine 3 parts of bis-PEG-18 methyl ether dimethylsilane 2.4 parts of microemulsion phase.

[0039] Comparative Example 2 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 2 parts 3 parts of bis-PEG-18 methyl ether dimethylsilane 2.4 parts of microemulsion phase.

[0040] Comparative Example 3 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 2 parts 0.2 parts of sodium bis(lauramide-glutamine)lysine 2.4 parts of microemulsion phase.

[0041] Comparative Example 4 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 2 parts 0.2 parts of sodium bis(lauramide-glutamine)lysine Three parts of bis-PEG-18 methyl ether dimethylsilane.

[0042] Comparative Example 5 The specific implementation method in this example is the same as in Example 1, except that, by weight, the raw material used for preparation is 2 parts of glycerol polyether-26.

[0043] Comparative Example 6 The specific implementation method of this example is the same as that of Example 1, except that, by weight, the raw material is 0.2 parts of sodium bis(lauramide-glutamine)lysine.

[0044] Comparative Example 7 The specific implementation method of this example is the same as that of Example 1, except that, by weight, the raw material is 3 parts of bis-PEG-18 methyl ether dimethylsilane.

[0045] Comparative Example 8 The specific implementation method in this example is the same as in Example 1, except that, by weight, the raw material is 2.4 parts of microemulsion phase.

[0046] Comparative Example 9 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 1 part 0.1 part of sodium bis(lauramide-glutamine)lysine 1.5 parts of bis-PEG-18 methyl ether dimethylsilane 2.4 parts of microemulsion phase.

[0047] Comparative Example 10 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 1 part 0.1 part of sodium bis(lauramide-glutamine)lysine 1.5 parts of bis-PEG-18 methyl ether dimethylsilane One microemulsion phase.

[0048] Comparative Example 11 The specific implementation method in this example is the same as in Example 1, except that the raw materials, by weight, are: Glyceryl polyether-26 4 parts 0.4 parts of sodium bis(lauramide-glutamine)lysine 6 parts of bis-PEG-18 methyl ether dimethylsilane Four microemulsion phases were prepared.

[0049] Figure 1 The figures show the visual results of the stickiness of the samples prepared in each embodiment and comparative example; a and m in the figures are the visual results of the stickiness of the samples prepared in Examples 1-2 and Comparative Examples 1-11, respectively.

[0050] Performance testing 1. Samples 1-13 were prepared by mixing the raw materials of the compositions of each embodiment and comparative example with Bosein and deionized water, respectively. The formulations of each sample are shown in Table 1-2 below, where / represents that the component is not present.

[0051] Table 1

[0052] Table 2

[0053] Visualization experiments were conducted on each sample: Experimental methods: (1) Take 3 drops of sample and add them to the 4×4 square on the back of the hand; (2) Apply evenly for 2 minutes until fully absorbed; (3) Gently place the back of your hand in the pile of foam balls, shake it three times, then place your hand flat on the table for a photograph, and count the foam balls using a counting camera; the experimental results are shown in Table 3 and Figure 1 .

[0054] Table 3

[0055] From the table above and Figure 1 As can be seen from the visualization experiment, the number of foam ball points in Example 1 was only 94, which was lower than the 113-165 of the corresponding samples in Comparative Examples 1-11. This also indicates that the composition provided in this application has the best effect on improving the sticky skin feel in a high concentration of BOXER (15% by mass) formulation system.

[0056] 2. Stickiness evaluation: Twelve subjects were selected and used products of sample 1 and samples 3-6 respectively. They rated the stickiness after absorption and obtained an average score of 0-5. The higher the score, the stronger the stickiness. The results are shown in Table 4.

[0057]

[0058] As can be seen from the table above, the composition provided in this application performs significantly better than the comparative examples in the stickiness evaluation. The average stickiness score of Sample 1 (Example 1) is only 1.83 points, which is significantly lower than the scores of Comparative Examples 1-4 (3.00 points, 3.08 points, 4.42 points, and 2.67 points, respectively). This result further verifies that the composition of the present invention can effectively reduce stickiness and improve the skin feel in high-concentration BOXER formulations.

[0059] 3. A high-concentration BOXER essence was prepared using the composition of Example 1. The formulation information is shown in Table 5 below.

[0060] Table 5

[0061] The preparation method is as follows: S1. At room temperature, premix phases B and F separately until homogeneous, and set aside for later use; S2. At room temperature, add a portion of phase A (1, 2) to the water pot, mix well, and then add it to the main pot. Add the remaining phase A (3, 4, 5, 6, 7) and phases B and C to the main pot, mix and heat to 82°C, and mix well. S3. Cool the main pot to 57°C, add phase D to the main pot, and mix well; S4. Cool the main pot to 42℃, add phases E and F to the main pot, mix well, and cool to room temperature to obtain a high-concentration BOXER essence.

[0062] This high-concentration Pro-Xylane serum was sent to SGS for human testing. Subjects: A total of 30 participants completed the assessment. They were healthy Chinese women with sensitive skin (screened by lactic acid stinging test), aged 33 to 50 years, with a mean age of 43.20 ± 4.16 years, and met the subject voluntary inclusion and exclusion criteria.

[0063] Assessment method: 30 valid subjects conducted self-skin feel assessment and scoring.

[0064] Rating criteria: 1 point indicates very dissatisfied, 2 points indicates somewhat dissatisfied, 3 points indicates some dissatisfied, 4 points indicates neither satisfied nor opposed, 5 points indicates somewhat satisfied, 6 points indicates relatively satisfied, and 7 points indicates very satisfied.

[0065] Satisfaction rate = (Number of participants with a score > 4) / (Number of valid participants) × 100%. Satisfaction rates are shown in Table 6 below.

[0066] Table 6

[0067] As shown in Table 6, the high-concentration Pro-Xylane serum prepared using the composition provided in this application exhibited excellent skin feel in human trials. Subjects generally reported that the serum did not feel sticky during application, had a light and easy-to-spread texture, and could be quickly and evenly applied to the skin and absorbed rapidly. After use, the skin felt refreshed, pleasant, gentle, and comfortable, without any discomfort. This fully demonstrates the significant effect of the composition provided in this application in improving the skin feel of high-concentration Pro-Xylane products.

Claims

1. A composition for improving the sticky skin feel of high concentrations of a bose factor, characterized in that, The raw materials for preparation include, by weight fraction: Glycerol polyether surfactant 2-4 parts Amino acid derivative surfactant 0.1-1 part Hydrophilic silicone derivative 0.5-6 parts Microemulsion phase 0.1-3.5 parts; The microemulsion phase includes polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, non-polar hydrocarbon oil, aliphatic glycol, and water.

2. The composition for improving the sticky skin feeling of high-concentration bose factors according to claim 1, characterized by, The mass ratio of the glycerol polyether surfactant, the amino acid derivative surfactant, the hydrophilic silicone derivative, and the microemulsion phase is (2-3):(0.2-0.5):(2-5):(1.5-3.5).

3. The composition for improving the sticky skin feeling of high-concentration bose factors according to claim 1, characterized by, The mass ratio of the glycerol polyether surfactant, the amino acid derivative surfactant, the hydrophilic silicone derivative, and the microemulsion phase is 2:0.2:3:2.

4.

4. The composition for improving the sticky skin feeling of high-concentration bose factors according to claim 1, characterized by, The glycerol polyether surfactant includes at least one of glycerol polyether-26, PEG-10 glyceryl isostearate, and PEG-7 glyceryl cocoate.

5. The composition for improving the sticky skin feeling of high-concentration bose factors according to claim 1, characterized by, The amino acid derivative surfactant includes at least one of sodium bis-lauramidoglutamidyl lysine, sodium lauroylmethylamino acetate, and sodium stearoyl glutamate.

6. The composition for improving the sticky skin feel of high-concentration bose factors according to claim 1, characterized by comprising, The hydrophilic silicone derivative includes at least one of bis-PEG-18 methyl ether dimethyl silane, PEG / PPG-18 / 18 dimethicone, and PEG-7 methyl ether dimethicone.

7. The composition for improving the sticky skin feel of high concentration of a bose factor according to claim 1, wherein The mass ratio of the polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, non-polar hydrocarbon oil, aliphatic glycol, and water is (0.2-0.8):(0.02-0.08):(0.2-0.8):(0.1-0.6):(0.1-0.6):(0.2-0.6):(0.1-0.3).

8. The composition for improving the sticky skin feeling of high-concentration bose factors according to claim 7, characterized by, The mass ratio of the polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, non-polar hydrocarbon oil, aliphatic glycol, and water is (0.3-0.6):(0.03-0.06):(0.4-0.6):(0.1-0.4):(0.1-0.4):(0.4-0.6):(0.2-0.3).

9. The composition for improving the sticky skin feeling of high-concentration bose factors according to claim 8, characterized by, The mass ratio of the polyoxyethylene hydrogenated castor oil, sorbitan sesquiisostearate, isostearyl alcohol, isostearic acid, non-polar hydrocarbon oil, aliphatic glycol, and water is 0.50:0.05:0.60:0.20:0.20:0.6:0.

25.

10. A method of preparing the composition for improving the sticky skin feel of high concentration of bose factors according to any one of claims 1-9, characterized in that, At least the following steps are included: The glycerol polyether surfactant, the amino acid derivative surfactant, the hydrophilic silicone derivative, and the microemulsion phase are stirred and mixed uniformly at 40-50°C to obtain the composition for improving the sticky skin feeling of high-concentration bovine growth factors.

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