Extraction equipment of heparin sodium

By using a scraper that monitors the condition of the small intestinal muscle layer in real time and employing water-assisted scraping technology, the problem of muscle layer damage during small intestinal mucosal scraping was solved, improving the efficiency of mucosal scraping and enzymatic hydrolysis, and ensuring the quality of heparin sodium extraction.

CN121465069APending Publication Date: 2026-02-06HUBEI YINUORUI BIOLOGICAL PHARMA
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Patent Information

Application Number
CN202511924083.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-19
Publication Date
2026-02-06

AI Technical Summary

Technical Problem

In existing technologies, it is difficult to accurately determine whether the muscle layer is damaged when scraping the small intestinal mucosa, which leads to difficulties in subsequent purification and affects product quality.

Method used

The scraper is used to scan the state of the small intestinal muscle layer in real time. The damage to the muscle layer is detected by an optical current transformer and the scraper position is adjusted. Combined with water injection and impeller to accelerate mucosal separation, the scraping efficiency and enzymatic hydrolysis efficiency are improved.

Benefits of technology

It effectively reduces the impact of muscle layer damage on mucosal quality, improves mucosal scraping efficiency and enzymatic hydrolysis efficiency, and ensures the quality of subsequent processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses heparin sodium extraction equipment, and belongs to the technical field of heparin sodium production, the heparin sodium extraction equipment comprises a machine body, the inner side and the outer side of the machine body are jointly provided with a detection component, the detection component comprises a connecting frame jointly and fixedly connected to the upper sides of sliding blocks located on the front side and the rear side, and the left side of the lower end of the connecting frame is fixedly connected with a first fixing plate; the left side and the right side of the first fixing plate are jointly provided with through holes in a transverse linear array in a penetrating mode, the upper sides of the interiors of the through holes are provided with limiting grooves, the interiors of the limiting grooves are slidably connected with limiting blocks, and the lower sides of the limiting blocks are fixedly connected with scrapers. In the process of scraping the small intestine mucosa by the scraper, the optical current transformer scans the state of the small intestine muscle layer in real time, and if the small intestine muscle layer is damaged, the position of the scraper can be adjusted in time, so that the influence of I / III type collagen released after the muscle layer is damaged on the quality of the mucosa is effectively reduced.
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Description

Technical Field

[0001] This invention relates to the field of heparin sodium production technology, and more specifically, to an extraction apparatus for heparin sodium. Background Technology

[0002] Heparin sodium is an anticoagulant and a naturally occurring sodium salt of sulfated glycosaminoglycans. It is primarily extracted from the intestinal mucosa or liver of pigs or cattle. Chemically, it is a strongly negatively charged mucopolysaccharide polymer composed of chain structures of varying molecular weights. Hydrolysis yields various sugar derivatives that interfere with many stages of the blood clotting process, exhibiting anticoagulant effects both in vivo and in vitro. Its mechanism of action is complex, primarily involving binding to antithrombin III (AT-III), thereby enhancing the latter's inhibitory effect on activated coagulation factors II, IX, X, XI, and XII. This results in the inhibition of platelet aggregation and destruction, hindering the formation of thromboplastin-activating enzymes, preventing the conversion of prothrombin to thrombin, and inhibiting thrombin, thus preventing fibrinogen from converting into fibrin, thereby exerting its anticoagulant effect.

[0003] To extract heparin sodium from pig small intestine, the pig small intestine must first be processed. After the fresh pig small intestine is delivered to the factory, the first step is cleaning. The staff will carefully rinse the pig small intestine with plenty of clean water to remove impurities, blood and residual feces from the surface. After cleaning, the staff will use professional tools to scrape off the small intestinal mucosa. It is necessary to ensure that the mucosa is scraped off completely, but not too deeply and damaging other tissues. The scraped small intestinal mucosa will be put into a mixer and pulverized into a paste. The purpose of this is to fully disperse the mucosa and provide better conditions for the subsequent enzymatic hydrolysis process. In existing technologies, if the muscular layer is damaged during the scraping of the small intestinal mucosa, type I / III collagen will be released and compete with heparin sodium for resin adsorption sites. Therefore, it is crucial to accurately determine whether the small intestinal muscular layer is damaged, as this directly affects the difficulty of subsequent purification and product quality. Summary of the Invention

[0004] In view of the problems existing in the prior art, the purpose of this invention is to provide a heparin sodium extraction device.

[0005] To solve the above problems, the present invention adopts the following technical solution, which can realize real-time scanning of the small intestinal muscle layer after scraping the small intestinal mucosa with a scraper, and adjust the scraper position in time if the small intestinal muscle layer is damaged.

[0006] A heparin sodium extraction device includes a body and a storage slot opened on the upper left side of the body. Electric guide rails are provided on both the front and rear sides of the upper end of the body. A slider is slidably connected inside the electric guide rails. Detection components are provided on both the inner and outer sides of the body. The detection component includes a connecting frame that is fixedly connected to the upper side of the front and rear sliders. A first fixing plate is fixedly connected to the lower left side of the connecting frame. The left and right sides of the first fixing plate are arranged in a horizontal linear array and have through holes. A limit groove is formed on the upper side of the inside of the through hole. A limit block is slidably connected inside the limit groove. A scraper is fixedly connected to the lower side of the limit block. A pressure spring is fixedly connected between the upper side of the limit block and the upper side of the inside of the limit groove. An optical current transformer is installed through the inside of the connecting frame.

[0007] Furthermore, a controller is provided on the upper side of the connecting frame, the scraper is located inside the through hole, and the shape of the limiting groove is adapted to the shape of the limiting block.

[0008] Furthermore, the inner and outer sides of the machine body are provided with a water injection assembly, which includes a second fixing plate fixedly connected to the lower right side of the connecting frame.

[0009] Furthermore, an expansion ring is fixedly connected to the left side of the second fixed plate in a horizontal linear array, the expansion ring passing through the second fixed plate. A conduit is fixedly connected to the right side of the body in a horizontal linear array. After the second fixed plate and the expansion ring move, they slide and fit on the outside of the conduit.

[0010] Furthermore, a counterweight cover is slidably overlapped on the upper side of the conduit, and rotating rods are fixedly connected to both the front and rear sides of the counterweight cover. Guide grooves are opened at both the front and rear ends of the right side inside the machine body. An inclined block is fixedly connected to the right side inside the guide groove. An inclined surface is provided on the lower side of the outer surface of the rotating rod. After the inclined surface of the rotating rod rolls, it presses against the inclined surface of the inclined block.

[0011] Furthermore, a first magnetic block is fixedly connected to the upper side of the counterweight cover, and a second magnetic block is fixedly connected to the upper right end of the machine body. The first magnetic block and the second magnetic block repel each other magnetically and do not directly contact each other. The right end of the conduit is connected to an external water supply device.

[0012] Furthermore, the interior of the machine body is provided with an agitation assembly, which includes a fixed frame that is fixedly connected to the front and rear sides of the lower end of the connecting frame.

[0013] Furthermore, an impeller is rotatably connected to the right side of the fixed frame, and the impeller is located inside the lower side of the machine body.

[0014] Furthermore, the interior of the machine body is provided with a collection component, which includes positioning plates fixedly connected to the left and right ends and the front and rear sides inside the machine body.

[0015] Furthermore, baffles are hinged to both the left and right ends of the upper side inside the body. A first storage frame is slidably attached to the upper side of the positioning plate. A first screen is provided inside the first storage frame. The first storage frame is located between the positioning plate and the baffle. A second storage frame is slidably attached to the upper side of the first screen. A second screen is provided on the lower side inside the second storage frame. The second storage frame is trapezoidal. A pull rod is fixedly connected to the upper inclined surface of the second storage frame.

[0016] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) The present invention uses a scraper to scrape the mucosa and then detects the state of the small intestine in real time. During the scraping process of the small intestine mucosa, the optical current transformer scans the state of the small intestine muscle layer in real time. If the small intestine muscle layer is damaged, the scraper position will be adjusted in time, which effectively reduces the impact of the type I / III collagen released after the muscle layer is damaged on the quality of the mucosa.

[0017] (2) The present invention uses a conduit to inject water into the small intestine during the process of scraping the mucosa, thereby improving the scraping efficiency of the mucosa. As the scraper scrapes the mucosa, the water mixed with compressed air will wash the inside of the small intestine, and the hydraulic expansion caused by the water will loosen the submucosa and accelerate the mucosa from the inside of the small intestine, thereby improving the scraping efficiency of the scraper.

[0018] (3) The present invention accelerates the flow of water inside the machine body by setting the impeller during the movement, so that the mucosa is slowly separated. After the machine body collects the mucosa, the impeller equipped with the fixed frame will accelerate the flow of water, so that the aggregated mucosa is slowly dispersed, avoiding the low enzyme permeability of the core area after the mucosa aggregates, which affects the subsequent enzymatic hydrolysis efficiency. It not only speeds up the enzymatic hydrolysis time, but also prevents the anaerobic environment of the aggregated core from causing an increase in the number of colonies. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of the present invention; Figure 2 This is a cross-sectional structural diagram of the present invention; Figure 3 This is a cross-sectional structural diagram of the body of the present invention; Figure 4 This is a cross-sectional view of the first storage frame of the present invention; Figure 5 This is a cross-sectional view of the counterweight cover of the present invention; Figure 6 This is a schematic diagram of the structure of the first fixing plate of the present invention; Figure 7 This is a cross-sectional view of the first fixing plate of the present invention; Figure 8This is a cross-sectional view of the connecting frame of the present invention.

[0020] Explanation of the labels in the diagram: 1. Body; 11. Storage slot; 12. Controller; 13. Electric guide rail; 14. Slider; 2. Detection component; 21. Connecting frame; 22. First fixing plate; 23. Through hole; 24. Limiting slot; 25. Limiting block; 26. Scraper; 27. Pressure spring; 28. Optical current transformer; 29. ​​Water injection assembly; 291. Conduit; 292. Second fixing plate; 293. Expansion ring; 294. Counterweight cover; 295. Rotating rod; 296. Guide groove; 297. Inclined block; 298. First magnetic block; 299. Second magnetic block; 3. Agitation assembly; 31. Fixing frame; 32. Impeller; 33. Collection component; 331. Positioning plate; 332. Baffle; 333. First storage frame; 334. First screen; 335. Second storage frame; 336. Second screen; 337. Pull rod. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.

[0022] Please see Figures 1 to 8 A heparin sodium extraction device includes a body 1 and a storage slot 11 opened on the upper left side of the body 1. Electric guide rails 13 are provided on both the front and rear sides of the upper end of the body 1. A slider 14 is slidably connected inside the electric guide rails 13. Detection components 2 are provided on both the inner and outer sides of the body 1. The detection component 2 includes a connecting frame 21 that is fixedly connected to the upper side of the sliders 14 on both the front and rear sides. A first fixing plate 22 is fixedly connected to the lower left side of the connecting frame 21. The left and right sides of the first fixing plate 22 are arranged in a horizontal linear array and have through holes 23. A limiting groove 24 is opened on the upper side of the through hole 23. A limiting block 25 is slidably connected inside the limiting groove 24. A scraper 26 is fixedly connected to the lower side of the limiting block 25. A pressure spring 27 is fixedly connected between the upper side of the limiting block 25 and the upper side of the inner side of the limiting groove 24. An optical current transformer 28 is installed through the inside of the connecting frame 21.

[0023] A controller 12 is provided on the upper side of the connecting frame 21, the scraper 26 is located inside the through hole 23, and the shape of the limiting groove 24 is adapted to the shape of the limiting block 25.

[0024] Water injection components 29 are provided on both the inner and outer sides of the body 1.

[0025] By adopting the above technical solution, one end of the small intestine is taken out from the storage groove 11 and inserted into the through hole 23 on the surface of the first fixing plate 22. At this time, the electromagnet attracts the limiting block 25 inside the limiting groove 24, causing the limiting block 25 to pull the scraper 26 upward. The limiting block 25 then squeezes the pressure spring 27 inside the limiting groove 24. When one end of the small intestine passes through the through hole 23 and contacts the component of the water injection assembly 29, the electromagnet releases its attraction to the limiting block 25. Subsequently, the pressure spring 27 pushes the limiting block 25, causing the scraper 26 to squeeze the small intestine. Then, the controller 12 starts the electric guide rail 13 above the machine body 1 to run, causing the slider 14 to slide inside the electric guide rail 13. During the sliding process of the slider 14 inside the electric guide rail 13, the connecting frame 21 above the slider 14 will drive the first fixing plate 22 and the small intestine fixed inside the through hole 23 to move to the right, so that the small intestine gradually detaches from the storage groove 11. When the electric guide rail 13 drives one end of the small intestine... When moved to the far right, the water injection component 29 will lock one end of the small intestine, and the electromagnet will adjust the attraction of the limiting block 25, so that the scraper 26 releases the pressure on the small intestine, but still contacts the upper side of the small intestine. Then, the electric guide rail 13 drives the connecting frame 21 to move to the left, so that the scraper 26 moves to the left and scrapes the mucosa inside the small intestine. During this process, the optical current transformer 28 inside the connecting frame 21 will scan the small intestine after the mucosa is scraped in real time. When the scanning signal is interrupted or the scattering is enhanced, the electromagnet at the corresponding position will slightly increase the attraction of the limiting block 25 until the scanning result feeds back a uniform high reflection signal, and the scraped mucosa will enter the body 1. Since the optical current transformer 28 scans the state of the small intestinal muscle layer in real time during the scraping of the small intestinal mucosa by the scraper 26, if the small intestinal muscle layer is damaged, the position of the scraper 26 will be adjusted in time, effectively reducing the impact of type I / III collagen released after muscle layer damage on the quality of the mucosa.

[0026] like Figures 1 to 5 and Figure 7 As shown, the water injection assembly 29 includes a second fixing plate 292 fixedly connected to the lower right side of the connecting frame 21.

[0027] An expansion ring 293 is fixedly connected to the left side of the second fixed plate 292 in a horizontal linear array. The expansion ring 293 passes through the second fixed plate 292. A conduit 291 is fixedly connected to the right side of the body 1 in a horizontal linear array. After the second fixed plate 292 and the expansion ring 293 move, they slide and are sleeved on the outside of the conduit 291.

[0028] A counterweight cover 294 is slidably overlapped on the upper side of the conduit 291. A rotating rod 295 is fixedly connected to both the front and rear sides of the counterweight cover 294. Guide grooves 296 are opened at both the front and rear ends of the right side inside the machine body 1. An inclined block 297 is fixedly connected to the right side inside the guide groove 296. An inclined surface is provided on the lower side of the outer surface of the rotating rod 295. After the inclined surface of the rotating rod 295 rolls, it presses against the inclined surface of the inclined block 297.

[0029] A first magnetic block 298 is fixedly connected to the upper side of the counterweight cover 294, and a second magnetic block 299 is fixedly connected to the upper right end of the body 1. The first magnetic block 298 and the second magnetic block 299 are magnetically repelled, and the first magnetic block 298 and the second magnetic block 299 are not in direct contact. The right end of the conduit 291 is connected to an external water supply device.

[0030] By adopting the above technical solution, after one end of the small intestine passes through the through hole 23, it can be fitted onto the outside of the expansion ring 293 on the left side of the second fixing plate 292. As the connecting frame 21 moves the small intestine to the outside of the catheter 291, the catheter 291 will push the small intestine, causing it to gradually detach from the outside of the expansion ring 293. During this process, the second fixing plate 292 pushes the counterweight cover 294 to move, causing the rotating rods 295 on both sides of the counterweight cover 294 to slide inside the guide groove 296. When the inclined surface of the rotating rod 295 contacts the inclined block 297 inside the guide groove 296, the counterweight will rotate ninety degrees. As the connecting frame 21 moves to the left... The mobile, external water supply device periodically injects water with a water-to-air ratio (mixed with compressed air) of 4:1 into the small intestine. At the same time, the first magnetic block 298 fixed on the surface of the counterweight cover 294 is pushed by the repulsion between it and the second magnetic block 299 on the upper part of the body 1, so that the counterweight cover 294 presses against the small intestine outside the tube 291. During the scraping of the mucosa by the scraper 26, the water flushing will accelerate the mucosa detachment. As the scraper 26 scrapes the mucosa, the water mixed with compressed air will flush the inside of the small intestine, and the hydraulic expansion caused by the water will loosen the submucosa and accelerate the detachment of the mucosa from the inside of the small intestine, thereby improving the scraping efficiency of the scraper 26.

[0031] like Figure 2 , Figure 3 and Figure 6 As shown, the machine body 1 is further provided with an agitation component 3 inside, which includes a fixed frame 31 fixedly connected to the front and rear sides of the lower end of the connecting frame 21.

[0032] An impeller 32 is rotatably connected to the right side of the fixed frame 31, and the impeller 32 is located inside the lower side of the body 1.

[0033] By adopting the above technical solution, during the movement of the connecting frame 21, the fixing frame 31 fixed on the lower side of the connecting frame 21 will drive the impeller 32 to move inside the body 1. When there is water inside the body 1, the impeller 32 driven by the fixing frame 31 will start to rotate under the water pressure inside the water source. After the impeller 32 rotates inside the water source, it will accelerate the flow of water, causing the aggregated mucosa to slowly disperse. Since the impeller 32 equipped with the fixing frame 31 will accelerate the flow of water after the body 1 collects the mucosa, the aggregated mucosa will be slowly washed away, avoiding the low enzyme permeability of the core area after the mucosa aggregates, which would affect the subsequent enzymatic hydrolysis efficiency. This not only speeds up the enzymatic hydrolysis time, but also prevents the anaerobic environment of the aggregated core from causing an increase in the colony count.

[0034] like Figures 1 to 4 As shown, the inside of the body 1 is provided with a collection component 33, which includes positioning plates 331 fixedly connected to the left and right ends and the front and rear sides inside the body 1.

[0035] Both the left and right ends of the upper side of the machine body 1 are hinged with baffles 332. The upper side of the positioning plate 331 is slidably connected to a first storage frame 333. The first storage frame 333 is provided with a first screen 334 inside. The first storage frame 333 is located between the positioning plate 331 and the baffle 332. The upper side of the first screen 334 is slidably connected to a second storage frame 335. The lower side of the interior of the second storage frame 335 is provided with a second screen 336. The second storage frame 335 is trapezoidal. The upper inclined surface of the second storage frame 335 is fixedly connected to a pull rod 337.

[0036] By adopting the above technical solution, the mucus scraped off by the scraper 26 enters the machine body 1 under the influence of water. At this time, the first collection frame 333 inside the machine body 1 collects the mucus. The first collection frame 333 is set inside the machine body 1 by the positioning plate 331 and the baffle 332. The baffle 332 is movable, so that the first collection frame 333 can be directly removed from the machine body 1. When it is necessary to remove the first collection frame 333 from the machine body 1, the water source and the mucus can be separated by the first screen 334. Before removing the first collection frame 333, one side of the first collection frame 333 can be pulled to tilt the first collection frame 333. Then, by pulling... Rod 337 pushes the second collection frame 335 inside the first collection frame 333. After the second collection frame 335 is pushed, it will scrape the mucus on the surface of the first screen 334 and collect it. The water that enters the second collection frame 335 will be discharged through the second screen 336, so that the mucus is collected by the second collection frame 335. Since the mucus collected by the first collection frame 333 still floats on the surface of the water source, the frequency of mucus aggregation is reduced. After the second collection frame 335 moves, it will collect the mucus above the first screen 334, so that the collection efficiency of the mucus is guaranteed, thereby ensuring the subsequent processing efficiency of the mucus.

[0037] Working principle: One end of the small intestine passes through the through hole 23 and fits onto the outside of the dilation ring 293. Then, the pressure spring 27 pushes the limiting block 25, causing the scraper 26 to squeeze the small intestine. Next, the controller 12 activates the electric guide rail 13 above the machine body 1, causing the slider 14 to move the connecting frame 21 above it. When the electric guide rail 13 moves one end of the small intestine to the far right, the small intestine fits onto the outside of the tube 291. When the connecting frame moves to the left, the small intestine disengages from the outside of the dilation ring 293. Simultaneously, the counterweight cover 294 locks the small intestine in place, and the connecting frame 21 moves to the left. During the process, the electromagnet adjusts the distance between the scraper 26 and the small intestine, causing the scraper 26 to begin scraping away the mucosa inside the small intestine. Meanwhile, the optical current transformer 28 inside the connecting frame 21 scans the small intestine in real time after the mucosa has been scraped away. When the scanning signal is interrupted or scattering intensifies, the electromagnet at the corresponding position slightly increases its attraction to the limiting block 25 until the scanning result returns a uniform, highly reflective signal. The scraped mucosa then enters the machine body 1. As the connecting frame 21 moves to the left, the external water supply device periodically fills the machine with water at a water-to-air ratio (mixed with compressed air) of 4:1. As the mucosa enters the small intestine, the water flushing accelerates its shedding. Simultaneously, the fixing bracket 31, located on the lower side of the connecting bracket 21, drives the impeller 32 to move within the body 1. When water is stored inside the body 1, the impeller 32, pushed by the fixing bracket 31, begins to rotate under the pressure of the water. This rotation accelerates the water flow, causing the accumulated mucosa to slowly disperse. The mucosa scraped by the scraper 26, propelled by the water, enters the body 1 and is collected by the first collection frame 333. When it is necessary to remove the first collection frame 333 from the body 1... When the part is removed, the water source and the mucus can be separated through the first screen 334. Before removing the first storage frame 333, one side of the first storage frame 333 can be pulled to tilt the first storage frame 333. Then, the second storage frame 335 inside the first storage frame 333 is pushed by the pull rod 337. After the second storage frame 335 is pushed, it will scrape the mucus on the surface of the first screen 334 and collect it. The water source that enters the second storage frame 335 will be discharged by the second screen 336, so that the mucus is collected by the second storage frame 335.

[0038] The above description is merely a preferred embodiment of the present invention; however, the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and its improved concepts, should be covered within the scope of protection of the present invention.

Claims

1. A heparin sodium extraction device, comprising a body (1) and a receiving groove (11) formed on the upper left side of the body (1), wherein electric guide rails (13) are provided on both the front and rear sides of the upper end of the body (1), and a slider (14) is slidably connected inside the electric guide rails (13), characterized in that: The inner and outer sides of the body (1) are equipped with detection components (2); The detection component (2) includes a connecting frame (21) that is fixedly connected to the upper side of the front and rear sliders (14). A first fixing plate (22) is fixedly connected to the lower left side of the connecting frame (21). The left and right sides of the first fixing plate (22) are arranged in a horizontal linear array and have through holes (23). A limiting groove (24) is opened on the upper side of the inside of the through hole (23). A limiting block (25) is slidably connected inside the limiting groove (24). A scraper (26) is fixedly connected to the lower side of the limiting block (25). A pressure spring (27) is fixedly connected between the upper side of the limiting block (25) and the upper side of the inside of the limiting groove (24). An optical current transformer (28) is installed through the inside of the connecting frame (21).

2. The heparin sodium extraction device according to claim 1, characterized in that: The upper side of the connecting frame (21) is provided with a controller (12), the scraper (26) is located inside the through hole (23), and the shape of the limiting groove (24) is adapted to the shape of the limiting block (25).

3. The heparin sodium extraction device according to claim 1, characterized in that: The inner and outer sides of the body (1) are provided with a water injection assembly (29), which includes a second fixing plate (292) fixedly connected to the lower right side of the connecting frame (21).

4. The heparin sodium extraction device according to claim 3, characterized in that: An expansion ring (293) is fixedly connected to the left side of the second fixing plate (292) in a horizontal linear array. The expansion ring (293) passes through the second fixing plate (292). A conduit (291) is fixedly connected to the right side of the body (1) in a horizontal linear array. After the second fixing plate (292) and the expansion ring (293) move, they slide and are sleeved on the outside of the conduit (291).

5. The heparin sodium extraction device according to claim 4, characterized in that: The upper side of the conduit (291) is slidably connected to a counterweight cover (294). The front and rear sides of the counterweight cover (294) are fixedly connected to rotating rods (295). The front and rear ends of the right side of the body (1) are provided with guide grooves (296). The right side of the inside of the guide groove (296) is fixedly connected to an inclined block (297). The lower side of the outer surface of the rotating rod (295) is provided with an inclined surface. After the inclined surface of the rotating rod (295) rolls, it presses against the inclined surface of the inclined block (297).

6. The heparin sodium extraction device according to claim 5, characterized in that: The upper side of the counterweight cover (294) is fixedly connected to a first magnetic block (298), and the upper right side of the body (1) is fixedly connected to a second magnetic block (299). The first magnetic block (298) and the second magnetic block (299) are magnetically repelled, and the first magnetic block (298) and the second magnetic block (299) are not in direct contact. The right end of the conduit (291) is connected to an external water supply device.

7. The heparin sodium extraction device according to claim 1, characterized in that: The machine body (1) is provided with an agitation assembly (3), which includes a fixed frame (31) fixedly connected to the front and rear sides of the lower end of the connecting frame (21).

8. The heparin sodium extraction device according to claim 7, characterized in that: An impeller (32) is rotatably connected to the right side of the fixed frame (31), and the impeller (32) is located on the lower inside of the body (1).

9. The heparin sodium extraction device according to claim 1, characterized in that: The body (1) is provided with a collection component (33), which includes a positioning plate (331) fixedly connected to the left and right ends and the front and rear sides inside the body (1).

10. The heparin sodium extraction device according to claim 9, characterized in that: Both the left and right ends of the upper side of the body (1) are hinged with baffles (332). The upper side of the positioning plate (331) is slidably connected to a first storage frame (333). The first storage frame (333) is provided with a first screen (334). The first storage frame (333) is located between the positioning plate (331) and the baffle (332). The upper side of the first screen (334) is slidably connected to a second storage frame (335). The lower side of the interior of the second storage frame (335) is provided with a second screen (336). The second storage frame (335) is trapezoidal. The upper inclined surface of the second storage frame (335) is fixedly connected to a pull rod (337).