Use of phenylalanine lactate for the preparation of a medicament for distinguishing between healthy people and hypertensive patients and for improving blood pressure in hypertensive patients

By using lactate phenylalanine as a biomarker and combining it with mass spectrometry to detect metabolites in biological samples, the problem of distinguishing between healthy people and hypertensive patients has been solved. Lactate phenylalanine drugs have been developed, which significantly improve blood pressure in hypertensive patients, achieving rapid and sensitive detection and treatment effects.

CN121577894BActive Publication Date: 2026-07-24BEIJING INST OF HEART LUNG & BLOOD VESSEL DISEASES
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING INST OF HEART LUNG & BLOOD VESSEL DISEASES
Filing Date
2025-11-19
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

Current technologies lack effective biomarkers to distinguish between healthy individuals and hypertensive patients, and there is a lack of drugs that can significantly improve blood pressure in hypertensive patients.

Method used

Using lactate phenylalanine as a biomarker, the levels of metabolites in biological samples were detected by mass spectrometry. The working characteristic curve was used to distinguish between healthy people and hypertensive patients. Lactate phenylalanine drugs were developed to improve hypertension. The content of multiple metabolites was detected by liquid chromatography-tandem mass spectrometry.

Benefits of technology

It enables rapid and sensitive differentiation between healthy individuals and hypertensive patients, significantly reduces blood pressure in hypertensive patients, provides a new drug for the treatment of hypertension, and the detection method is simple and efficient.

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Abstract

The application belongs to the technical field of biological medicine, and particularly relates to application of phenylalanine lactate in preparation of medicines for distinguishing healthy people from hypertension patients and improving blood pressure of hypertension patients. The application discloses phenylalanine lactate, medicines for detecting phenylalanine lactate, and application of phenylalanine lactate as a marker in preparation of medicines for distinguishing healthy people from hypertension patients. The application provides application of phenylalanine lactate in preparation of medicines for preventing, improving or treating hypertension. Meanwhile, the application also provides a detection method of phenylalanine lactate, and improves accuracy of biological sample detection. The application can prevent, improve or treat hypertension by detecting content of phenylalanine lactate in a biological sample and supplementing phenylalanine lactate.
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Citation Information

Patent Citations

  • US20230296622A1