Traditional Chinese medicine composition for treating plateau chronic cough

By using traditional Chinese medicine ingredients such as Fritillaria thunbergii in the form of tea, granules, or decoctions, this treatment targets the "dryness, heat, and deficiency" pathogenesis of chronic cough at high altitudes, clearing heat and resolving phlegm, moistening the lungs and relieving cough, thus solving the treatment challenges of chronic cough at high altitudes and achieving significant symptom relief and improved quality of life.

CN121668258APending Publication Date: 2026-03-17CHENGDU MILITARY GENERAL HOSPITAL OF PLA
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Patent Information

Application Number
CN202511741415.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-11-25
Publication Date
2026-03-17

AI Technical Summary

Technical Problem

Chronic cough in high-altitude areas lacks effective Western medical treatments, traditional Chinese medicine lacks prepared medicines, and existing Chinese medicine treatments are not very effective, resulting in a prolonged course of the disease and affecting patients' quality of life.

Method used

A traditional Chinese medicine composition is used, including Fritillaria thunbergii, Arctium lappa root, Asparagus cochinchinensis, Bambusa textilis, Morus alba root bark, Terminalia chebula, Citrus reticulata peel, Houttuynia cordata, Adenophora stricta, Astragalus membranaceus, and Siraitia grosvenorii. Based on the principles of syndrome differentiation and treatment in traditional Chinese medicine, it is prepared as a tea, granules, or decoction to target the pathogenesis of "dryness, heat, and deficiency" in the high-altitude environment. It clears heat and resolves phlegm, moistens the lungs and relieves cough, and treats both the symptoms and the root cause.

Benefits of technology

It significantly relieves symptoms of chronic cough at high altitudes, shortens the cough relief time, improves patients' quality of life, has high safety, and has an overall effective rate of 83.33%.

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating plateau chronic cough, which is prepared from the following raw materials in parts by weight: 2-30 parts of thunberg fritillary bulb, 2-30 parts of burdock root, 1-15 parts of radix asparagi, 1-15 parts of bamboo shavings, 1-15 parts of honey white mulberry root-bark, 1-15 parts of fructus chebulae, 1-10 parts of pericarpium citri reticulatae, 1-15 parts of herba houttuyniae, 1-15 parts of radix glehniae, 2-30 parts of radix astragali and 2-10 parts of fructus momordicae.
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Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine technology, and in particular relates to a traditional Chinese medicine composition for treating chronic cough at high altitudes. Background Technology

[0002] Chronic cough is defined as a cough lasting ≥8 weeks, with no obvious evidence of lung disease on chest X-ray. Cough is often the only symptom that prompts a patient's medical attention. Chronic cough is one of the most common clinical symptoms of the respiratory system.

[0003] The most common causes of chronic cough include upper airway cough syndrome, caused by the reflux of secretions from diseases of the nose, pharynx, and larynx (such as rhinitis and sinusitis), which irritates the throat. It is characterized by daytime coughing, postnasal drip, or a feeling of a foreign body in the throat. Reflux of stomach contents, such as stomach acid, irritates the esophagus and throat, triggering coughing. It may be accompanied by acid reflux and heartburn, but coughing may be the only symptom. Treatment with antacids is required and the course of treatment is relatively long. There is also chronic dry cough related to allergies, with normal lung function and provocation tests, but there may be a history of allergies or abnormal allergy markers; treatment with anti-allergy medications is effective. Other causes include drug-induced cough, early-stage interstitial lung disease, and psychogenic cough.

[0004] High-altitude areas are characterized by low oxygen, high cold, low pressure, high radiation, strong winds and sandstorms, and dry air. Soldiers stationed on high-altitude areas have their respiratory tracts exposed to the external environment for a long time, making them prone to chronic cough. The course of the disease is long and easily affected by various factors, leading to repeated attacks and prolonged illness, which can greatly affect the patient's quality of life.

[0005] For chronic cough at high altitudes, Western medicine lacks effective treatments, and traditional Chinese medicine lacks effective prepared medicines. This type of condition falls under the category of "chronic cough" in traditional Chinese medicine, and its location is in the lungs. "The upper burner is like a feather; it cannot fly without being cleared," therefore, most Chinese medicines used to treat this type of disease are those with a light and refreshing aroma. Summary of the Invention

[0006] To address the aforementioned technical problems, embodiments of the present invention provide a traditional Chinese medicine composition for treating chronic cough at high altitudes.

[0007] To achieve the above objectives, the embodiments of the present invention adopt the following technical solutions: On one hand, the present invention provides a traditional Chinese medicine composition for treating chronic cough at high altitudes, comprising the following raw materials by weight: 2-30 parts of Fritillaria thunbergii, 2-30 parts of Arctium lappa root, 1-15 parts of Asparagus cochinchinensis, 1-15 parts of Bambusa textilis, 1-15 parts of Morus alba root bark, 1-15 parts of Terminalia chebula, 1-10 parts of Citrus reticulata peel, 1-15 parts of Houttuynia cordata, 1-15 parts of Adenophora stricta, 2-30 parts of Astragalus membranaceus, and 2-10 parts of Siraitia grosvenorii.

[0008] In some embodiments, a traditional Chinese medicine composition for treating chronic cough at high altitudes comprises, by weight, the following ingredients: 2-20 parts of Fritillaria thunbergii, 2-25 parts of Arctium lappa root, 1-10 parts of Asparagus cochinchinensis, 1-12 parts of Bambusa textilis, 1-13 parts of Morus alba root bark, 2-12 parts of Terminalia chebula, 1-8 parts of Citrus reticulata peel, 2-12 parts of Houttuynia cordata, 5-15 parts of Adenophora stricta, 3-25 parts of Astragalus membranaceus, and 2-8 parts of Siraitia grosvenorii.

[0009] In some embodiments, a traditional Chinese medicine composition for treating chronic cough at high altitudes comprises, by weight, the following ingredients: 2-18 parts of Fritillaria thunbergii, 2-20 parts of Arctium lappa root, 2-8 parts of Asparagus cochinchinensis, 2-10 parts of Bambusa textilis, 3-10 parts of Morus alba root bark, 5-10 parts of Terminalia chebula, 2-8 parts of Citrus reticulata peel, 5-12 parts of Houttuynia cordata, 5-10 parts of Adenophora stricta, 5-25 parts of Astragalus membranaceus, and 3-8 parts of Siraitia grosvenorii.

[0010] In some embodiments, a traditional Chinese medicine composition for treating chronic cough at high altitudes comprises, by weight, the following ingredients: 5-15 parts of Fritillaria thunbergii, 5-15 parts of Arctium lappa root, 3-8 parts of Asparagus cochinchinensis, 5-10 parts of Bambusa textilis, 5-10 parts of Morus alba root bark, 5-8 parts of Terminalia chebula, 3-8 parts of Citrus reticulata peel, 5-10 parts of Houttuynia cordata, 6-10 parts of Adenophora stricta, 10-20 parts of Astragalus membranaceus, and 5-8 parts of Siraitia grosvenorii.

[0011] In some embodiments, a traditional Chinese medicine composition for treating chronic cough at high altitudes comprises, by weight, the following ingredients: 10 parts of Fritillaria thunbergii, 8 parts of Arctium lappa root, 5 parts of Asparagus cochinchinensis, 10 parts of Bambusa textilis, 5 parts of Morus alba root bark, 8 parts of Terminalia chebula, 5 parts of Citrus reticulata peel, 10 parts of Houttuynia cordata, 10 parts of Adenophora stricta, 20 parts of Astragalus membranaceus, and 5 parts of Siraitia grosvenorii.

[0012] This invention discloses a traditional Chinese medicine composition for treating chronic cough at high altitudes. It can be brewed as a tea, made into granules, or decocted into a soup for consumption. This herbal tea is based on the principles of traditional Chinese medicine's syndrome differentiation and treatment, combining suitable Chinese herbs into a formula. It is then brewed with boiling water and consumed at any time to achieve disease prevention and body conditioning. It is not only a common method for treating mild and chronic diseases but also an important measure for daily health maintenance.

[0013] The tea in this formula is a tea substitute for treating chronic cough at high altitudes, formulated under the guidance of traditional Chinese medicine theories, methods, prescriptions, and medicines, based on a combination of syndrome differentiation and disease differentiation. The formula includes Fritillaria thunbergii, burdock root, asparagus root, bamboo shavings, honey-processed mulberry bark, Terminalia chebula, dried tangerine peel, houttuynia cordata, Adenophora stricta, Astragalus membranaceus, and monk fruit.

[0014] Fritillaria thunbergii: Bitter and cold in nature. It enters the lung and heart meridians.

[0015] Burdock root: Bitter and slightly sweet in taste, cool in nature. It enters the lung and heart meridians.

[0016] Asparagus: Sweet and bitter in taste, cold in nature. It enters the lung and kidney meridians.

[0017] Bamboo shavings: sweet in taste, slightly cold in nature. They enter the lung, stomach, heart, and gallbladder meridians.

[0018] Honey-processed mulberry bark: slightly cold in nature, sweet in taste, and enters the lung meridian.

[0019] Terminalia chebula: It has a bitter, sour, and astringent taste, and enters the lung and large intestine meridians.

[0020] Dried tangerine peel: It is bitter, pungent, and warm in nature, and enters the lung and spleen meridians.

[0021] Houttuynia cordata: It has a pungent taste, is cold in nature, and enters the lung meridian.

[0022] North American ginseng: Sweet, bitter, and bland in taste; cool in nature. Enters the lung and spleen meridians.

[0023] Astragalus: It has a sweet taste and slightly warm properties, and enters the lung and spleen meridians.

[0024] Monk fruit: sweet and cool in nature, and enters the lung and large intestine meridians.

[0025] In the high-altitude environment, external pathogens easily stagnate and transform into heat, forming phlegm-heat. Fritillaria thunbergii clears and resolves phlegm-heat, relieving stagnation and dispersing nodules; Houttuynia cordata clears heat and detoxifies, specifically eliminating lung abscesses. Together, these two herbs clear "lung heat and phlegm stagnation" caused by high-altitude stress and infection, serving as the principal herbs. Burdock root soothes the throat and detoxifies, mulberry bark moistens dryness and relieves asthma, and monk fruit clears heat and moistens the lungs, serving as the assistant herbs. Their powerful moisturizing properties directly counteract the "dryness" of the high altitude, relieving dry cough and sore throat, while simultaneously clearing lung heat through bowel movements (the lungs and large intestine are internally and externally related). Astragalus membranaceus, Adenophora stricta, and Asparagus cochinchinensis tonify qi and nourish yin; bamboo shavings and tangerine peel resolve phlegm and regulate qi; Terminalia chebula astringes the lungs and stops cough, serving as the adjuvant herbs.

[0026] This comprehensive approach fully embodies the principles of traditional Chinese medicine (TCM) in "differentiation of syndromes and treatment based on syndrome differentiation" and "adaptation to the three factors (time, place, and individual)." Targeting the core pathogenesis of chronic cough at high altitudes—characterized by "dryness, heat, and deficiency"—it employs a combined approach of tonifying and purging. Fritillaria thunbergii and Houttuynia cordata clear heat and resolve phlegm to expel pathogens, while Astragalus membranaceus and Adenophora stricta tonify qi and nourish yin to support the body's resistance. Simultaneously, it moistens and nourishes the lungs with Siraitia grosvenorii and Asparagus cochinchinensis to combat dryness, and Citrus reticulata peel to dry dampness and resolve phlegm, preventing the accumulation of body fluids into phlegm. While dispersing lung heat, Terminalia chebula astringes lung qi, ensuring that the elimination of pathogens does not harm the body's resistance, achieving a balance between dispersing and astringing. Therefore, this invention, a TCM composition for treating chronic cough at high altitudes, can be considered a comprehensive treatment for chronic cough caused by the unique environment of high altitudes. Attached Figure Description

[0027] Figure 1 Images of the throat before treatment, 7 days, and 14 days later: a) Throat image of the treatment group before treatment; b) Throat image of the treatment group 7 days after treatment; c) Throat image of the treatment group 14 days after treatment; d) Throat image of the waiting group before treatment; e) Throat image of the waiting group 7 days after treatment; f) Throat image of the waiting group 14 days after treatment. Detailed Implementation

[0028] The technical solutions in some embodiments of this disclosure are described clearly and completely below. Obviously, the described embodiments are only some embodiments of this disclosure, and not all embodiments. Based on the embodiments provided in this disclosure, all other embodiments obtained by those skilled in the art are within the scope of protection of this disclosure.

[0029] Example 1

[0030] Steep 2g of Fritillaria thunbergii, 2g of burdock root, 1g of asparagus root, 1g of bamboo shavings, 1g of honey-processed mulberry bark, 1g of Terminalia chebula, 1g of dried tangerine peel, 1g of houttuynia cordata, 1g of Adenophora stricta, 2g of Astragalus membranaceus, and 2g of Siraitia grosvenorii in boiling water for 10 minutes before drinking.

[0031] Example 2

[0032] Steep 3g of Fritillaria thunbergii, 5g of burdock root, 2g of asparagus root, 2g of bamboo shavings, 3g of honey-processed mulberry bark, 3g of Terminalia chebula, 2g of dried tangerine peel, 2g of houttuynia cordata, 4g of Adenophora stricta, 2g of Astragalus membranaceus, and 2g of Siraitia grosvenorii in boiling water for 11 minutes before drinking.

[0033] Example 3

[0034] Steep 5g of Fritillaria thunbergii, 3g of Arctium lappa root, 3g of Asparagus cochinchinensis, 3g of Bambusa textilis, 2g of Morus alba root bark, 2g of Terminalia chebula, 3g of Citrus reticulata peel, 2g of Houttuynia cordata, 3g of Adenophora stricta, 5g of Astragalus membranaceus, and 3g of Siraitia grosvenorii in boiling water for 12 minutes before drinking.

[0035] Example 4

[0036] Steep 6g of Fritillaria thunbergii, 5g of Arctium lappa root, 10g of Asparagus cochinchinensis, 3g of Bambusa textilis, 5g of Morus alba root bark, 6g of Terminalia chebula, 5g of Citrus reticulata peel, 3g of Houttuynia cordata, 4g of Adenophora stricta, 5g of Astragalus membranaceus, and 6g of Siraitia grosvenorii in boiling water for 16 minutes before drinking.

[0037] Example 5

[0038] Steep 10g of Fritillaria thunbergii, 10g of Arctium lappa root, 5g of Asparagus cochinchinensis, 5g of Bambusa textilis, 8g of Morus alba root bark, 10g of Terminalia chebula, 5g of Citrus reticulata peel, 5g of Houttuynia cordata, 5g of Adenophora stricta, 10g of Astragalus membranaceus, and 5g of Siraitia grosvenorii in boiling water for 18 minutes before drinking.

[0039] Example 6

[0040] Prepare granules from 15g of Fritillaria thunbergii, 10g of Arctium lappa root, 8g of Asparagus cochinchinensis, 5g of Bambusa textilis, 8g of Morus alba root bark, 5g of Terminalia chebula, 8g of Citrus reticulata peel, 5g of Houttuynia cordata, 10g of Adenophora stricta, 10g of Astragalus membranaceus, and 5g of Siraitia grosvenorii. Mix with water and it is ready to drink.

[0041] Example 7

[0042] Prepare granules from 10g of Fritillaria thunbergii, 20g of Arctium lappa root, 5g of Asparagus cochinchinensis, 15g of Bambusa textilis, 10g of Morus alba root bark, 11g of Terminalia chebula, 5g of Citrus reticulata peel, 10g of Houttuynia cordata, 8g of Adenophora stricta, 15g of Astragalus membranaceus, and 5g of Siraitia grosvenorii. Mix well with water and it is ready to drink.

[0043] Example 8

[0044] Prepare granules from 20g of Fritillaria thunbergii, 20g of Arctium lappa root, 15g of Asparagus cochinchinensis, 10g of Bambusa textilis, 5g of Morus alba root bark, 10g of Terminalia chebula, 5g of Citrus reticulata peel, 10g of Houttuynia cordata, 5g of Adenophora stricta, 10g of Astragalus membranaceus, and 5g of Siraitia grosvenorii. Mix well with water and it is ready to drink.

[0045] Example 9

[0046] Prepare granules from 15g of Fritillaria thunbergii, 15g of Arctium lappa root, 10g of Asparagus cochinchinensis, 5g of Bambusa textilis, 10g of Morus alba root bark, 5g of Terminalia chebula, 5g of Citrus reticulata peel, 10g of Houttuynia cordata, 10g of Adenophora stricta, 10g of Astragalus membranaceus, and 5g of Siraitia grosvenorii. Mix well with water and it is ready to drink.

[0047] Example 10

[0048] Prepare granules from 15g of Fritillaria thunbergii, 20g of burdock root, 15g of asparagus root, 10g of bamboo shavings, 10g of honey-processed mulberry bark, 10g of Terminalia chebula, 10g of dried tangerine peel, 15g of Houttuynia cordata, 10g of Adenophora stricta, 20g of Astragalus membranaceus, and 10g of Siraitia grosvenorii. Mix with water and it is ready to drink.

[0049] Example 11

[0050] Boil 30g of Fritillaria thunbergii, 30g of Arctium lappa root, 15g of Asparagus cochinchinensis, 15g of Bambusa textilis, 15g of Morus alba root bark, 15g of Terminalia chebula, 10g of Citrus reticulata peel, 15g of Houttuynia cordata, 15g of Adenophora stricta, 30g of Astragalus membranaceus, and 10g of Siraitia grosvenorii in water to make a decoction, which can then be consumed.

[0051] Example 12

[0052] Boil 25g of Fritillaria thunbergii, 30g of Arctium lappa root, 10g of Asparagus cochinchinensis, 15g of Bambusa textilis, 10g of Morus alba root bark, 15g of Terminalia chebula, 10g of Citrus reticulata peel, 10g of Houttuynia cordata, 15g of Adenophora stricta, 20g of Astragalus membranaceus, and 10g of Siraitia grosvenorii in water to make a decoction, which can then be consumed.

[0053] Example 13

[0054] Boil 30g of Fritillaria thunbergii, 30g of Arctium lappa root, 15g of Asparagus cochinchinensis, 15g of Bambusa textilis, 15g of Morus alba root bark, 15g of Terminalia chebula, 10g of Citrus reticulata peel, 15g of Houttuynia cordata, 15g of Adenophora stricta, 30g of Astragalus membranaceus, and 10g of Siraitia grosvenorii in water to make a decoction, which can then be consumed.

[0055] Example 14

[0056] Boil 25g of Fritillaria thunbergii, 20g of Arctium lappa root, 15g of Asparagus cochinchinensis, 10g of Bambusa textilis, 15g of Morus alba root bark, 15g of Terminalia chebula, 10g of Citrus reticulata peel, 15g of Houttuynia cordata, 10g of Adenophora stricta, 25g of Astragalus membranaceus, and 8g of Siraitia grosvenorii in water to make a decoction, which can then be consumed.

[0057] Example 15

[0058] Boil 10g of Fritillaria thunbergii, 8g of Arctium lappa root, 5g of Asparagus cochinchinensis, 10g of Bambusa textilis, 5g of Morus alba root bark, 8g of Terminalia chebula, 5g of Citrus reticulata peel, 10g of Houttuynia cordata, 10g of Adenophora stricta, 20g of Astragalus membranaceus, and 5g of Siraitia grosvenorii in water to make a decoction, which can then be consumed.

[0059] Clinical efficacy and safety analysis of the composition of this invention for treating patients with chronic cough at high altitudes.

[0060] 1. Research Methods 1.1 Cases and Grouping According to relevant diagnostic, inclusion, and exclusion criteria, 60 patients diagnosed with chronic cough at high altitudes between August 11, 2025 and September 11, 2025 were included. Their ages ranged from 18 to 45 years, and gender was not limited. Patients were randomly divided into a treatment group (n=30) and a waiting-for-treatment group (n=30) based on their consultation time (numbered 1-60). The treatment group received one dose of the herbal composition obtained in Example 15, twice a day, for 14 consecutive days, using the same preparation method as before. The waiting-for-treatment group received one dose of the herbal composition obtained in Example 15, twice a day, 14 days after enrollment, for 14 consecutive days, using the same preparation method as before.

[0061] The treatment group recorded changes in various symptoms and signs after 7 and 14 days of drinking the product.

[0062] 1.2 Diagnostic criteria 1.2.1 Western Medicine Diagnostic Criteria Referencing the Pulmonary Diseases Committee of the Internal Medicine Branch of the China Association of Traditional Chinese Medicine, the Traditional Chinese Medicine Diagnosis and Treatment of Cough. The National Consensus Opinion (2011 Edition) established the diagnostic criteria for chronic cough: cough lasting for more than 8 weeks, with no obvious abnormalities seen on chest X-ray.

[0063] 1.2.1 Traditional Chinese Medicine Diagnostic Criteria Traditional Chinese Medicine Diagnostic Criteria, Pulmonary Diseases Committee of Internal Medicine Branch of China Association of Traditional Chinese Medicine. Expert Consensus on the Diagnosis and Treatment of Cough with Traditional Chinese Medicine (2011 Edition), taking into account the characteristics of chronic cough at high altitudes, is as follows: The main symptom is cough, which is dry cough or with little phlegm, and the phlegm is sticky and difficult to cough up; it may be accompanied by dry throat, itchy throat, dry mouth without thirst or little water intake, sore throat, and a feeling of a foreign body in the throat. Symptoms are worse after talking a lot or in the afternoon or evening. (2) The tongue is red with little or thin white coating, and the pulse is thready and rapid or thready and weak; (3) Susceptible to colds, fatigue, weak voice, thirst, spontaneous sweating and night sweats, easily induced or aggravated by wind and cold; 1.3 Inclusion Criteria (1) Meets the above diagnostic criteria and is able to cooperate with the research and treatment of patients; (2) The subjects voluntarily participated in the clinical trial and signed an informed consent form; (3) Those with complete clinical data; (4) Residing in a plateau region for more than one month.

[0064] 1.4 Exclusion Criteria (1) Medication for treating throat conditions has been used within the past 7 days; (2) Pregnant or lactating women; (3) Individuals allergic to this drug; 1.5 Shedding Criteria (1) Severe adverse reactions, allergies, etc. occur; (2) Those who fail to take medication as prescribed; (3) Lost-to-follow-up patients; (4) Patients in the waiting treatment group whose condition deteriorated rapidly during the waiting period and who urgently needed medication. The reasons for dropout in dropout cases are recorded and not included in the statistical data.

[0065] 1.6 Observation Indicators 1.6.1 Cough relief time and throat condition The cough relief time of the two groups of patients was recorded, along with throat images before treatment, 7 days after treatment, and 14 days after treatment.

[0066] 1.6.2 Traditional Chinese Medicine Syndrome Scoring The symptoms include cough, sticky sputum, chest tightness, shortness of breath, and itchy throat.

[0067] 1.6.3 Security Indicators (1) If any adverse events occur during the study, record in detail the time of occurrence, clinical symptoms and signs, duration, severity, effective measures taken and outcome.

[0068] (2) General vital signs: body temperature, heart rate, respiration, blood pressure, etc.

[0069] 1.6.4 Therapeutic Indicators Cured is defined as the near disappearance of symptoms such as cough, itchy throat, and phlegm; significantly effective is defined as improvement in symptoms such as cough, itchy throat, and phlegm; ineffective is defined as no significant improvement in symptoms such as cough. The total effective rate is calculated as [(number of cured cases + number of significantly effective cases) / total number of cases] × 100%. In Traditional Chinese Medicine (TCM) syndrome scoring, 0 points represents no symptoms, 1 point represents mild, 2 points represents moderate, and 3 points represents severe.

[0070] 1.7 Statistical Analysis Statistical analysis was performed using SPSS 26.0. Data conforming to a normal distribution were analyzed using independent samples t-tests between groups and paired samples t-tests within groups. Data not conforming to a normal distribution were analyzed using the rank-sum test. Categorical data were expressed using the chi-square test. 2 For small sample sizes, the rank-sum test was used. P < 0.05 indicates that the difference is statistically significant.

[0071] 2. Research Results 2.1 Cough relief time and throat condition The cough relief time was 10.97±5.42 days in the treatment group and 16.33±4.63 days in the waiting group, showing a significant difference between the two groups. p <0.05 (Table 1). Throat images of the two groups before treatment, 7 days after treatment, and 14 days after treatment are shown below. Figure 1 As shown, the number of pharyngeal follicles in the treatment group decreased significantly after 14 days of treatment, while no significant changes were observed in the waiting treatment group.

[0072] Table 1 Group n Cough relief time (days) Treatment group 30 10.97±5.42 Waiting for treatment group 30 16.33±4.63 value 4.126 value <0.05 2.2 Comparison of TCM syndrome scores before and after treatment Before treatment, there was no significant difference in the total scores of TCM symptoms and signs between the two groups (P>0.05). After 7 and 14 days of treatment, the total scores of symptoms and signs in the treatment group were significantly lower than those in the waiting group at the same time point (P<0.05). The total scores of symptoms and signs in both groups after 7 and 14 days of treatment were significantly lower than those before treatment (P<0.05), as shown in Table 2.

[0073] Table 2 Comparison of TCM syndrome scores before and after treatment Treatment group Waiting for treatment group Before treatment 10.97±5.72 10.49±5.04 7 days of treatment 7.37±4.63*# 8.97±4.77* 14 days of treatment 3.94±3.88*# 7.89±5.35* Note: * P < 0.05, compared with pre-treatment values ​​in this group; # P < 0.05, compared with the waiting-for-treatment group at the same time.

[0074] 2.3 Safety Evaluation During the study, the patients' body temperature, heart rate, respiration, blood pressure, and other indicators remained stable, and no adverse events occurred. The safety assessment was Level 1.

[0075] 2.4 Overall effective rate of treatment in the two groups of patients A comparison of the clinical efficacy between the two groups of patients revealed that the total effective rate was 83.33% in the treatment group and 50.00% in the waiting group, with a statistically significant difference (P < 0.05), as shown in Table 3.

[0076] Table 3 Comparison of clinical efficacy

[0077] Note: * P < 0.05, compared with the waiting treatment group In the description of this specification, specific features, structures, materials, or characteristics may be combined in any suitable manner in one or more embodiments or examples.

[0078] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention should be included within the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be determined by the scope of the claims.

Claims

1. A traditional Chinese medicine composition for treating high altitude chronic cough, characterized in that, The following raw materials are included by weight parts: Fritillaria thunbergii Miq. 2-30 parts, burdock root 2-30 parts, Asparagus cochinchinensis (Lour.) Merr. 1-15 parts, bamboo shavings 1-15 parts, honeyed mulberry bark 1-15 parts, Terminalia chebula Retz. 1-15 parts, dried tangerine or orange peel 1-10 parts, Houttuynia cordata Thunb. 1-15 parts, Radix Adenophorae 1-15 parts, Astragalus membranaceus (Fisch.) Bunge 2-30 parts, and Momordica grosvenori Swingle 2-10 parts.

2. The Chinese medicine composition for treating chronic cough at high altitude according to claim 1, characterized in that, The following raw materials are included by weight parts: Fritillaria thunbergii Miq. 2-20 parts, burdock root 2-25 parts, Asparagus cochinchinensis (Lour.) Merr. 1-10 parts, bamboo shavings 1-12 parts, honeyed mulberry bark 1-13 parts, Terminalia chebula Retz. 2-12 parts, dried tangerine or orange peel 1-8 parts, Houttuynia cordata Thunb. 2-12 parts, Radix Adenophorae 5-15 parts, Astragalus membranaceus (Fisch.) Bunge 3-25 parts, and Momordica grosvenori Swingle 2-8 parts.

3. The Chinese medicine composition for treating chronic cough at high altitude according to claim 1, characterized in that, The following raw materials are included by weight parts: Fritillaria thunbergii Miq. 2-18 parts, burdock root 2-20 parts, Asparagus cochinchinensis (Lour.) Merr. 2-8 parts, bamboo shavings 2-10 parts, honeyed mulberry bark 3-10 parts, Terminalia chebula Retz. 5-10 parts, dried tangerine or orange peel 2-8 parts, Houttuynia cordata Thunb. 5-12 parts, Radix Adenophorae 5-10 parts, Astragalus membranaceus (Fisch.) Bunge 5-25 parts, and Momordica grosvenori Swingle 3-8 parts.

4. The Chinese medicine composition for treating chronic cough at high altitude according to claim 1, characterized in that, The following raw materials are included by weight parts: Fritillaria thunbergii Miq. 5-15 parts, burdock root 5-15 parts, Asparagus cochinchinensis (Lour.) Merr. 3-8 parts, bamboo shavings 5-10 parts, honeyed mulberry bark 5-10 parts, Terminalia chebula Retz. 5-8 parts, dried tangerine or orange peel 3-8 parts, Houttuynia cordata Thunb. 5-10 parts, Radix Adenophorae 6-10 parts, Astragalus membranaceus (Fisch.) Bunge 10-20 parts, and Momordica grosvenori Swingle 5-8 parts.

5. The Chinese medicine composition for treating chronic cough at high altitude according to claim 1, characterized in that, The following raw materials are included by weight parts: Fritillaria thunbergii Miq. 10 parts, burdock root 8 parts, Asparagus cochinchinensis (Lour.) Merr. 5 parts, bamboo shavings 10 parts, honeyed mulberry bark 5 parts, Terminalia chebula Retz. 8 parts, dried tangerine or orange peel 5 parts, Houttuynia cordata Thunb. 10 parts, Radix Adenophorae 10 parts, Astragalus membranaceus (Fisch.) Bunge 20 parts, and Momordica grosvenori Swingle 5 parts.