Composition for beriberi, onychomycosis, tinea corporis and pruritus cutanea

By combining a combination of fresh Sichuan pepper, artemisia annua, mugwort, perilla, vitex leaves, acorus calamus alcohol extract, and aloe vera juice, the lack of effectiveness in treating athlete's foot, onychomycosis, tinea corporis, and pruritus in existing technologies has been solved, achieving significant preventive and therapeutic effects.

CN122070929APending Publication Date: 2026-05-22四川曾氏御邸科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
四川曾氏御邸科技有限公司
Filing Date
2024-11-22
Publication Date
2026-05-22

AI Technical Summary

Technical Problem

Existing treatments are ineffective for athlete's foot, onychomycosis, tinea corporis, and pruritus, and are prone to recurrence; there are also no specific drugs available.

Method used

This treatment utilizes a combination of alcoholic extracts of fresh Sichuan pepper, artemisia annua, mugwort, perilla, vitex leaves, and acorus calamus, along with pressed aloe vera juice, to achieve symptomatic treatment by inhibiting bacteria, reducing the release of inflammatory mediators, and promoting wound healing.

Benefits of technology

It significantly reduces the recurrence rate of athlete's foot, onychomycosis, tinea corporis, and pruritus, providing better prevention and treatment effects.

✦ Generated by Eureka AI based on patent content.
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Abstract

The invention relates to a composition for beriberi, onychomycosis, tinea corporis and skin pruritus. The composition is prepared from the following component materials: fresh pepper alcohol extract, sweet wormwood alcohol extract, folium artemisiae argyi alcohol extract, perilla alcohol extract, negundo chastetree leaf alcohol extract, rhizoma acori graminei alcohol extract and aloe squeezed juice. The composition contains a plurality of bactericidal and anti-inflammatory substances which act together, and the fresh pepper alcohol extract has the effects of easing pain, resisting bacteria and diminishing inflammation; the artemisia apiacea alcohol extract inhibits the activity of inflammatory cells, reduces release of inflammatory mediators and can inhibit various fungi; the folium artemisiae argyi alcohol extract inhibits virus breeding and propagation; the perilla alcohol extract can inhibit pathogenic bacteria; the vitex negundo leaf alcohol extract and the rhizoma acori graminei alcohol extract can inhibit various bacteria and fungi, and the aloe squeezed juice has the effects of resisting virus infection and promoting wound recovery and can nourish skin. The composition has good prevention and treatment effects on beriberi, onychomycosis, tinea corporis and pruritus cutanea.
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Description

Technical Field

[0001] This invention belongs to the field of composition technology, and specifically relates to a composition for athlete's foot, onychomycosis, tinea corporis, and pruritus. Background Technology

[0002] Athlete's foot is a fungal infection of the foot caused by dermatophytes. It is usually classified into vesicular, squamous-keratotic, and erosive types, and may cause symptoms such as blisters, peeling, cracking, and erosion. Athlete's foot is a contagious skin disease that can be transmitted from person to person. Tinea unguium, also known as onychomycosis, is mainly caused by dermatophytes invading the nail plate and nail bed. It is actually a type of onychomycosis (infection of the fingernails and toenails caused by fungi such as dermatophytes, yeasts, and non-dermatophytes). Epidemiological data shows that the incidence of onychomycosis in the general population is 2% to 18%, and there are regional differences in China. Symptoms of onychomycosis vary depending on the type of infection; the nail plate may appear cloudy, thickened, separated, discolored, atrophied, detached, lifted, with an uneven surface, hooked nails, and paronychia. Tinea corporis is a superficial fungal infection of the skin caused by pathogenic fungi that parasitize the smooth skin of the human body (excluding the skin of the hands, feet, hair, nails, and groin). When pathogenic fungi invade the stratum corneum of the skin, they can cause a mild inflammatory reaction, resulting in lesions such as erythema, papules, and vesicles, followed by desquamation, often in a ring-like pattern, hence the common names tinea corporis or ringworm. These frequently occurring symptoms are generally treated with antibiotics or preventative measures, but because there is no specific antifungal drug, recurrence is common. Therefore, it is necessary to provide a special combination for treatment or prevention. Summary of the Invention

[0003] The purpose of this invention is to provide a composition for athlete's foot, onychomycosis, tinea corporis, and pruritus, which facilitates better prevention or treatment of these conditions and reduces their recurrence rate.

[0004] To achieve the above objectives, the technical solution of the present invention is as follows.

[0005] A composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus comprises the following components: fresh Sichuan pepper alcohol extract, artemisia annua alcohol extract, mugwort alcohol extract, perilla alcohol extract, vitex trifolia leaf alcohol extract, acorus calamus alcohol extract, and aloe vera juice.

[0006] Furthermore, the composition of the above composition is as follows: in 100 parts by weight, fresh Sichuan pepper alcohol extract accounts for 20-30 parts, artemisia annua alcohol extract accounts for 10-15 parts, mugwort alcohol extract accounts for 10-20 parts, perilla alcohol extract accounts for 10-25 parts, vitex trifolia leaf alcohol extract accounts for 10-20 parts, acorus calamus alcohol extract accounts for 5-10 parts, and aloe vera juice accounts for 10-15 parts.

[0007] Furthermore, the composition of the above-mentioned composition is as follows: 20 parts of fresh Sichuan pepper alcohol extract, 10 parts of artemisia annua alcohol extract, 20 parts of mugwort alcohol extract, 25 parts of perilla alcohol extract, 10 parts of vitex trifolia leaf alcohol extract, 5 parts of acorus calamus alcohol extract, and 10 parts of aloe vera juice.

[0008] Furthermore, the composition of the above-mentioned composition is as follows: 25 parts of fresh Sichuan pepper alcohol extract, 15 parts of artemisia annua alcohol extract, 15 parts of mugwort alcohol extract, 10 parts of perilla alcohol extract, 10 parts of vitex trifolia leaf alcohol extract, 10 parts of acorus calamus alcohol extract, and 15 parts of aloe vera juice.

[0009] Furthermore, the composition of the above-mentioned composition is as follows: 30 parts of fresh Sichuan pepper alcohol extract, 10 parts of artemisia annua alcohol extract, 10 parts of mugwort alcohol extract, 10 parts of perilla alcohol extract, 20 parts of vitex trifolia leaf alcohol extract, 5 parts of acorus calamus alcohol extract, and 15 parts of aloe vera juice.

[0010] Further, the preparation steps of the fresh Sichuan pepper alcohol extract are as follows: fresh Sichuan pepper is washed clean and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:8, and extracted by shaking in a water bath at 45°C for 3 hours. Then, it is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered with activated carbon to obtain the fresh Sichuan pepper alcohol extract.

[0011] Further, the preparation steps of the artemisia annua alcohol extract are as follows: Artemisia annua is cleaned and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:8, and extracted by shaking in a water bath at 45°C for 3 hours. Then, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered with activated carbon to obtain the artemisia annua alcohol extract.

[0012] Further, the preparation steps of the mugwort extract are as follows: clean the mugwort leaves and air-dry them, mix them with edible alcohol at a solid-liquid ratio of 1:6, and extract them by shaking in a water bath at 45°C for 2 hours. Then filter the mixture, collect the filtrate, centrifuge to remove impurities, and filter with activated carbon to obtain the mugwort alcohol extract.

[0013] Further, the preparation steps of the perilla alcohol extract are as follows: fresh perilla is washed and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:9, and extracted by shaking in a water bath at 45°C for 4 hours. Then, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered with activated carbon to obtain the perilla alcohol extract.

[0014] Further, the preparation steps of the Vitex negundo leaf alcohol extract are as follows: fresh Vitex negundo leaves are washed clean and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:8, and extracted by shaking in a water bath at 45°C for 2 hours. Then, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered with activated carbon to obtain the Vitex negundo leaf alcohol extract.

[0015] Further, the fresh Acorus calamus is cleaned, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:30. The mixture is then extracted by shaking in a water bath at 45°C for 3 hours. After filtration, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Acorus calamus alcohol extract.

[0016] Furthermore, the aloe vera juice is a viscous juice obtained by pulping fresh aloe vera leaves and then filtering it using a filter press.

[0017] The functions and effects of the above-mentioned components are as follows:

[0018] (1) Fresh Sichuan pepper alcohol extract: The main functions of fresh Sichuan pepper alcohol extract include analgesia, antibacterial and anti-inflammatory effects, and dispelling cold and dampness. Fresh Sichuan pepper contains chemical components such as cinnamon, which have a certain analgesic effect. After being soaked in alcohol, these effective components may be extracted, helping to relieve pain. Fresh Sichuan pepper has a strong antibacterial and anti-inflammatory effect, especially against some common bacteria and fungi. After being soaked in alcohol, its antibacterial and anti-inflammatory effect may be enhanced, and it can be used to relieve local wounds, inflammation, and other problems.

[0019] (2) Artemisia annua alcoholic extract: Artemisia annua extract has anti-inflammatory effects, inhibiting the activity of inflammatory cells and reducing the release of inflammatory mediators, thus having a certain therapeutic effect on inflammatory diseases such as arthritis and dermatitis. Studies have shown that the minimum inhibitory concentration (MIC) of Artemisia annua extract against Aspergillus niger and Penicillium erythrorhizium is 1.25%, and against Penicillium is 5%. In addition, artemisinin-based drugs also have significant antifungal activity against Pneumocystis carinii, Cryptococcus neoformans, and Aspergillus fumigatus.

[0020] (3) Artemisia argyi alcohol extract: Artemisia argyi extract contains a variety of natural medicinal components. After the human body absorbs these medicinal components, it can enhance the body's anti-allergy ability and reduce the occurrence of various allergic diseases. In addition, it also has a certain therapeutic effect on common skin diseases such as allergic dermatitis, eczema, and scabies. Artemisia argyi extract retains most of the medicinal components in Artemisia argyi, which can not only eliminate a variety of bacteria in the human body, but also inhibit the growth and reproduction of viruses in the human body.

[0021] (4) Perilla alcohol extract: Perilla extract has antibacterial, astringent, and antipruritic effects on the skin. Perilla extract has a certain inhibitory effect on pathogens, thus playing an antibacterial role. Clinically, it can be used to treat diseases caused by bacterial infections, such as folliculitis and boils. Perilla extract can constrict capillaries, thereby achieving an antipruritic effect. Clinically, it can be used to relieve symptoms such as itchy skin and urticaria. Perilla extract also has a certain antipruritic effect on the skin, relieving symptoms such as itching and redness caused by insect bites.

[0022] (5) Vitex negundo leaf alcohol extract: The alcohol extract of Vitex negundo leaf has significant antibacterial activity. Studies have shown that the ethanol extract of Vitex negundo leaf has inhibitory effects on various bacteria and fungi. The extract of Vitex negundo leaf has inhibitory effects on Escherichia coli, Bacillus subtilis, Bacillus thuringiensis, Staphylococcus aureus, Rhizopus, Penicillium, Aspergillus niger, and Ganoderma lucidum. The extract of Vitex negundo leaf has a significant inhibitory effect on bacteria such as Escherichia coli, Bacillus subtilis, Bacillus thuringiensis, and Staphylococcus aureus. The extract of Vitex negundo leaf has a very strong inhibitory effect on the mycelial growth of Ganoderma lucidum.

[0023] (6) Acorus tatarinowii alcohol extract: Acorus tatarinowii alcohol extract has a significant inhibitory effect on various pathogenic fungi and bacteria. Studies have shown that Acorus tatarinowii ethanol extract has significant antibacterial activity against 15 pathogenic fungi, especially after 48 and 96 hours of treatment, the inhibition rate against apple anthracnose fungus and walnut twig blight fungus is over 90%. Acorus tatarinowii extract also has a significant antibacterial effect against bacteria such as Escherichia coli, Bacillus subtilis, and Staphylococcus aureus, with a bactericidal rate of over 94.5%. The active ingredients in Acorus tatarinowii extract, such as asarone, have the effects of clearing the mind, sterilizing and reducing inflammation, and activating the meridians. These ingredients can eliminate oxygen free radicals and promote the metabolic function of the dermis. The main components of Acorus tatarinowii extract include volatile oil and asarone. After ethanol extraction, these components can significantly inhibit the growth of various pathogenic fungi and bacteria, and have a broad antibacterial spectrum and strong antibacterial activity.

[0024] (7) Aloe vera juice: Aloe vera contains aloin A, wound hormones, and polysaccharide mannan, which have antiviral effects and promote wound healing. Aloe vera juice has anti-inflammatory properties. Because aloe vera has certain antimicrobial activity, including inhibiting the growth and reproduction of certain bacteria, fungi, and viruses, it can reduce inflammatory reactions and itching.

[0025] The beneficial effects of this invention are as follows: The composition, consisting of alcoholic extracts of fresh Sichuan pepper, artemisia annua, mugwort, perilla, vitex negundo, and acorus calamus, along with pressed aloe vera juice, exhibits good preventative and therapeutic effects against athlete's foot, onychomycosis, tinea corporis, and pruritus. The composition utilizes the synergistic interaction of multiple anti-inflammatory substances: Sichuan pepper alcoholic extract provides analgesia, antibacterial and anti-inflammatory effects; artemisia annua extract inhibits the activity of inflammatory cells and reduces the release of inflammatory mediators; mugwort extract inhibits viral growth and reproduction; perilla extract inhibits pathogens; vitex negundo and acorus calamus alcoholic extracts inhibit various bacteria and fungi; and pressed aloe vera juice has antiviral and wound-healing properties. These components work together to inhibit pathogens and reduce their release, providing antibacterial, anti-inflammatory, and analgesic effects, thus achieving good preventative and therapeutic effects against athlete's foot, onychomycosis, tinea corporis, and pruritus. Detailed Implementation

[0026] The specific embodiments of the present invention will be described below in conjunction with examples to provide a better understanding of the present invention.

[0027] Example 1

[0028] The composition for athlete's foot, onychomycosis, tinea corporis, and pruritus in this embodiment has the following mass components: 20 parts of fresh Sichuan pepper alcohol extract, 10 parts of Artemisia annua alcohol extract, 20 parts of Artemisia argyi alcohol extract, 25 parts of Perilla frutescens alcohol extract, 10 parts of Vitex negundo leaf alcohol extract, 5 parts of Acorus tatarinowii alcohol extract, and 10 parts of aloe vera juice. The preparation steps for the fresh Sichuan pepper alcohol extract are as follows: fresh Sichuan pepper is washed, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is then extracted using a water bath method at 45°C for 3 hours with shaking. After extraction, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the fresh Sichuan pepper alcohol extract. The preparation steps for the Artemisia annua alcohol extract are as follows: Artemisia annua is washed, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is then extracted using a water bath method at 45°C for 3 hours with shaking. After extraction, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Artemisia annua alcohol extract. The preparation steps for the Artemisia argyi extract are as follows: Artemisia argyi leaves are washed and air-dried, then mixed with edible alcohol at a solid-liquid ratio of 1:6. The mixture is extracted using a water bath method with shaking at 45°C for 2 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Artemisia argyi alcohol extract. The preparation steps for the Perilla frutescens alcohol extract are as follows: Fresh Perilla frutescens leaves are washed and pulped, then mixed with edible alcohol at a solid-liquid ratio of 1:9. The mixture is extracted using a water bath method with shaking at 45°C for 4 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Perilla frutescens alcohol extract. The preparation steps for the Vitex negundo leaf alcohol extract are as follows: Fresh Vitex negundo leaves are washed and pulped, then mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is extracted using a water bath method with shaking at 45°C for 2 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Vitex negundo leaf alcohol extract. The process involves cleaning fresh Acorus calamus, pulping it, mixing it with edible alcohol at a solid-liquid ratio of 1:30, and then extracting it using a water bath method at 45°C for 3 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Acorus calamus alcohol extract. The aloe vera juice is a viscous juice obtained by pulping fresh aloe vera leaves and filtering it using a filter press.

[0029] When the composition of this embodiment is mixed, it is used to treat patients with athlete's foot. It is applied to the affected area of ​​the athlete's foot. A follow-up study of 150 patients with athlete's foot showed that 100 patients experienced significant improvement in their athlete's foot and were cured after 7 days.

[0030] When the composition of this embodiment is mixed, it is used to treat patients with onychomycosis. It is applied to the onychomycosis area of ​​the patient. 80 patients with athlete's foot were followed up. 65 patients showed significant improvement in their onychomycosis and were cured after 7 days.

[0031] When the composition of this embodiment is mixed, it is used to treat patients with tinea corporis. It is applied to the affected area of ​​the tinea corporis. In a follow-up study of 120 patients with athlete's foot, tinea corporis disappeared significantly in 80 patients, and the disease was cured after 5 days.

[0032] When the composition of this embodiment is mixed, it is used to treat patients with pruritus. It is applied to the itchy areas of the patient's skin. In a follow-up study of 80 patients with athlete's foot, 70 patients experienced significant relief from itching and were cured after 7 days.

[0033] Example 2

[0034] The composition for athlete's foot, onychomycosis, tinea corporis, and pruritus in this embodiment has the following mass components: 25 parts of fresh Sichuan pepper alcohol extract, 15 parts of Artemisia annua alcohol extract, 15 parts of Artemisia argyi alcohol extract, 10 parts of Perilla frutescens alcohol extract, 10 parts of Vitex negundo leaf alcohol extract, 10 parts of Acorus tatarinowii alcohol extract, and 15 parts of aloe vera juice. The preparation steps for the fresh Sichuan pepper alcohol extract are as follows: fresh Sichuan pepper is washed, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is then extracted using a water bath at 45°C with shaking for 3 hours. After extraction, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the fresh Sichuan pepper alcohol extract. The preparation steps for the Artemisia annua alcohol extract are as follows: Artemisia annua is washed, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is then extracted using a water bath at 45°C with shaking for 3 hours. After extraction, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Artemisia annua alcohol extract. The preparation steps for the Artemisia argyi extract are as follows: Artemisia argyi leaves are washed and air-dried, then mixed with edible alcohol at a solid-liquid ratio of 1:6. The mixture is extracted using a water bath method with shaking at 45°C for 2 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Artemisia argyi alcohol extract. The preparation steps for the Perilla frutescens alcohol extract are as follows: Fresh Perilla frutescens leaves are washed and pulped, then mixed with edible alcohol at a solid-liquid ratio of 1:9. The mixture is extracted using a water bath method with shaking at 45°C for 4 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Perilla frutescens alcohol extract. The preparation steps for the Vitex negundo leaf alcohol extract are as follows: Fresh Vitex negundo leaves are washed and pulped, then mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is extracted using a water bath method with shaking at 45°C for 2 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Vitex negundo leaf alcohol extract. The process involves cleaning fresh Acorus calamus, pulping it, mixing it with edible alcohol at a solid-liquid ratio of 1:30, and then extracting it using a water bath method at 45°C for 3 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Acorus calamus alcohol extract. The aloe vera juice is a viscous juice obtained by pulping fresh aloe vera leaves and filtering it using a filter press.

[0035] When the composition of this embodiment is mixed, it is used to treat patients with athlete's foot. It is applied to the affected area of ​​the athlete's foot. A follow-up study of 120 patients with athlete's foot showed that 90 patients experienced significant improvement in their athlete's foot and were cured after 7 days.

[0036] When the composition of this embodiment is mixed, it is used to treat patients with onychomycosis. It is applied to the onychomycosis area of ​​the patient. 70 patients with athlete's foot were followed up. 50 patients showed significant improvement in their onychomycosis and were cured after 7 days.

[0037] When the composition of this embodiment is mixed, it is used to treat patients with tinea corporis. It is applied to the affected area of ​​the tinea corporis. In a follow-up study of 110 patients with athlete's foot, 90 patients showed significant disappearance of tinea corporis and were cured after 5 days.

[0038] When the composition of this embodiment is mixed, it is used to treat patients with pruritus. It is applied to the itchy areas of the patient's skin. In a follow-up study of 70 patients with athlete's foot, 60 patients experienced significant relief from itching and were cured after 7 days.

[0039] Example 3

[0040] The composition for athlete's foot, onychomycosis, tinea corporis, and pruritus in this embodiment has the following mass components: 30 parts of fresh Sichuan pepper alcohol extract, 10 parts of Artemisia annua alcohol extract, 10 parts of Artemisia argyi alcohol extract, 10 parts of Perilla frutescens alcohol extract, 20 parts of Vitex negundo leaf alcohol extract, 5 parts of Acorus tatarinowii alcohol extract, and 15 parts of aloe vera juice. The preparation steps for the fresh Sichuan pepper alcohol extract are as follows: fresh Sichuan pepper is washed, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is then extracted using a water bath at 45°C with shaking for 3 hours. After extraction, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the fresh Sichuan pepper alcohol extract. The preparation steps for the Artemisia annua alcohol extract are as follows: Artemisia annua is washed, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is then extracted using a water bath at 45°C with shaking for 3 hours. After extraction, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Artemisia annua alcohol extract. The preparation steps for the Artemisia argyi extract are as follows: Artemisia argyi leaves are washed and air-dried, then mixed with edible alcohol at a solid-liquid ratio of 1:6. The mixture is extracted using a water bath method with shaking at 45°C for 2 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Artemisia argyi alcohol extract. The preparation steps for the Perilla frutescens alcohol extract are as follows: Fresh Perilla frutescens leaves are washed and pulped, then mixed with edible alcohol at a solid-liquid ratio of 1:9. The mixture is extracted using a water bath method with shaking at 45°C for 4 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Perilla frutescens alcohol extract. The preparation steps for the Vitex negundo leaf alcohol extract are as follows: Fresh Vitex negundo leaves are washed and pulped, then mixed with edible alcohol at a solid-liquid ratio of 1:8. The mixture is extracted using a water bath method with shaking at 45°C for 2 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Vitex negundo leaf alcohol extract. The process involves cleaning fresh Acorus calamus, pulping it, mixing it with edible alcohol at a solid-liquid ratio of 1:30, and then extracting it using a water bath method at 45°C for 3 hours. The extract is then filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Acorus calamus alcohol extract. The aloe vera juice is a viscous juice obtained by pulping fresh aloe vera leaves and filtering it using a filter press.

[0041] When the composition of this embodiment is mixed, it is used to treat patients with athlete's foot. It is applied to the affected area of ​​the athlete's foot. A follow-up study of 120 patients with athlete's foot showed that 100 patients experienced significant improvement in their athlete's foot and were cured after 7 days.

[0042] When the composition of this embodiment is mixed, it is used to treat patients with onychomycosis. It is applied to the onychomycosis area of ​​the patient. 70 patients with athlete's foot were followed up. 60 patients showed significant improvement in their onychomycosis and were cured after 7 days.

[0043] When the composition of this embodiment is mixed and used to treat patients with tinea corporis, it is applied to the affected area. In a follow-up study of 80 patients with athlete's foot, 65 patients showed significant disappearance of tinea corporis and were cured after 5 days.

[0044] When the composition of this embodiment is mixed, it is used to treat patients with pruritus. It is applied to the itchy areas of the patient's skin. In a follow-up study of 90 patients with athlete's foot, 80 patients experienced significant relief from itching and were cured after 7 days.

[0045] The above description represents the preferred embodiments of the present invention. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of the present invention, and these improvements and modifications are also considered to be within the scope of protection of the present invention.

Claims

1. A composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus, characterized in that: It is composed of the following components: fresh Sichuan pepper alcohol extract, artemisia alcohol extract, mugwort alcohol extract, perilla alcohol extract, vitex leaf alcohol extract, acorus alcohol extract, and aloe vera juice.

2. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The composition comprises the following components by weight: in 100 parts by weight, fresh Sichuan pepper alcohol extract accounts for 20-30 parts, artemisia annua alcohol extract accounts for 10-15 parts, mugwort alcohol extract accounts for 10-20 parts, perilla alcohol extract accounts for 10-25 parts, vitex trifolia leaf alcohol extract accounts for 10-20 parts, acorus calamus alcohol extract accounts for 5-10 parts, and aloe vera juice accounts for 10-20 parts.

3. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The composition comprises the following components by weight: 20 parts of fresh Sichuan pepper alcohol extract, 10 parts of artemisia annua alcohol extract, 20 parts of mugwort alcohol extract, 25 parts of perilla alcohol extract, 10 parts of vitex trifolia leaf alcohol extract, 5 parts of acorus calamus alcohol extract, and 10 parts of aloe vera juice.

4. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The preparation steps of the fresh Sichuan pepper alcohol extract are as follows: fresh Sichuan pepper is cleaned, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:

8. The mixture is then extracted by shaking in a water bath at 45°C for 3 hours. After filtration, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the fresh Sichuan pepper alcohol extract.

5. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The preparation steps of the artemisia annua alcohol extract are as follows: Artemisia annua is cleaned and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:8, and extracted by shaking in a water bath at 45°C for 3 hours. Then, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered with activated carbon to obtain the artemisia annua alcohol extract.

6. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The preparation steps of the Artemisia argyi extract are as follows: wash the Artemisia argyi clean and air dry it, mix it with edible alcohol at a solid-liquid ratio of 1:6, and extract it by shaking in a water bath at 45°C for 2 hours. Then filter it, collect the filtrate, centrifuge to remove impurities, and filter it with activated carbon to obtain the Artemisia argyi alcohol extract.

7. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The preparation steps of the perilla alcohol extract are as follows: fresh perilla is washed and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:9, and extracted by shaking in a water bath at 45°C for 4 hours. Then, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the perilla alcohol extract.

8. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The preparation steps of the Vitex negundo leaf alcohol extract are as follows: fresh Vitex negundo leaves are washed and pulped, mixed with edible alcohol at a solid-liquid ratio of 1:8, and extracted by shaking in a water bath at 45°C for 2 hours. Then, the mixture is filtered, the filtrate is collected, centrifuged to remove impurities, and filtered with activated carbon to obtain the Vitex negundo leaf alcohol extract.

9. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The fresh Acorus calamus was cleaned, pulped, and mixed with edible alcohol at a solid-liquid ratio of 1:

30. The mixture was then extracted by shaking in a water bath at 45°C for 3 hours. The extract was then filtered, the filtrate was collected, centrifuged to remove impurities, and filtered through activated carbon to obtain the Acorus calamus alcohol extract.

10. The composition for treating athlete's foot, onychomycosis, tinea corporis, and pruritus according to claim 1, characterized in that: The aloe vera juice is a viscous juice obtained by pulping fresh aloe vera leaves and then filtering it using a filter press.