Essence composition with skin whitening effect

Abstract

The present invention provides an essence composition having a skin whitening effect, and more particularly, to an essence composition having not only a skin whitening effect but also an effect of preventing skin aging.

Description

Technical Field

[0001] This invention relates to an essence composition having a skin whitening effect, and more specifically, not only to an essence composition having a skin whitening effect, but also to an essence composition having an anti-aging effect on the skin. Background Technology

[0002] Skin is a membrane covering the outside of the body. It has a variety of physiological functions that protect the body from various external stimuli, obstacles, dryness and other environmental factors, and plays a role in protecting and regulating internal organs and other internal organs.

[0003] However, with age, the secretion of various hormones that regulate metabolism decreases, and the function and activity of immune cells decline. This leads to a reduction in the biosynthesis of immune proteins and biological constituent proteins required by the body. External factors such as ozone layer depletion and other environmental pollution, which cause an increase in ultraviolet radiation, free radiation, and reactive oxygen species, result in physical and chemical stimuli and stress that weaken the normal function of the skin, causing aging, poor blood color, wrinkles, and other issues.

[0004] To reduce skin irritation from various chemicals and achieve superior skin-improving effects, the cosmetics industry is developing products using natural water. Natural ingredients not only have fewer side effects on the skin but also exhibit excellent skin-improving properties. Recently, with increased consumer response to cosmetics using natural ingredients, their development value as cosmetic raw materials has further increased.

[0005] Existing technical documents

[0006] Patent documents

[0007] (Patent Document 1) Korean Patent Registration No. 10-2476660 (Publication Date: 2022.12.07) Summary of the Invention

[0008] The problem that the invention aims to solve

[0009] The present invention was made in view of the above circumstances, and its purpose is to provide an essence composition that not only has skin whitening effect but also anti-skin aging effect.

[0010] means for solving problems

[0011] To address the aforementioned issues, the skin-whitening essence composition of the present invention comprises an aqueous phase component and an oil phase component.

[0012] In a preferred embodiment of the invention, the aqueous phase may include purified water and plant extracts.

[0013] In a preferred embodiment of the invention, the paid component may include a compound represented by the following chemical formula 1.

[0014] [Chemical Formula 1]

[0015]

[0016] In the chemical formula 1, R1, R2, R3, R4, R5 and R6 are each independently an alkoxy group from C1 to C10.

[0017] In one desired embodiment of the present invention, the essence composition of the present invention may include, for 100 parts by weight of purified water, compounds 1 to 2 represented by the chemical formula 1.

[0018] In one desired embodiment of the present invention, the essence composition of the present invention may include 5 to 15 parts by weight of plant extracts for 100 parts by weight of purified water.

[0019] In one intended embodiment of the present invention, the plant extract may include evening primrose hot water extract, evening primrose seed extract, sycamore leaf ethanol extract, and mulberry leaf ethanol extract.

[0020] In a preferred embodiment of the invention, the plant extracts per 10% by weight may include 20-40% by weight of evening primrose hot water extract, 20-40% by weight of evening primrose seed extract, 10-30% by weight of eucalyptus leaf ethanol extract and 10-30% by weight of mulberry leaf ethanol extract.

[0021] Invention Effects

[0022] The skin-whitening essence composition of the present invention not only has a skin-whitening effect, but also has an anti-aging effect. Detailed Implementation

[0023] Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings, so as to facilitate implementation by those skilled in the art. The present invention can be implemented in many different forms and is not limited to the embodiments described herein. For clarity of illustration in the drawings, parts unrelated to the description have been omitted, and the same reference numerals are used throughout the description for the same or similar components.

[0024] The skin-whitening essence composition of the present invention comprises an aqueous phase component and an oil phase component.

[0025] Aqueous phase component is a component comprising one or more aqueous phase components, such as water, including purified water, and may include one or more water selected from sodium periodate, bauxite, glycerin, glycerides, 1,2-adipic acid diol, hyaluronic acid, and plant extracts, preferably including purified water, periodate diol, propylene glycol, malonic acid, glycerides, glycerides, plant diols, diols, and glyceryl diol extracts. It may include...

[0026] Sodium hyaluronate is a moisturizing ingredient. For 100g of purified water, it can include 0.05-0.3g by weight, preferably 0.07-0.15g by weight. Meeting this weight range, the essence composition of this invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0027] Allantoin is a moisturizing ingredient. For 100g of purified water, it can include 0.1-0.4g, preferably 0.15-0.25g. Within this weight range, the essence composition of the present invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0028] Glycerin is a moisturizing ingredient. For 100g of purified water, it can include 15.0-21.0g by weight, preferably 17.0-19.0g by weight. Meeting this weight range, the serum composition of this invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0029] Glyceryl stearate is an emulsifier that can be present in 1.0 to 4.0 parts by weight of purified water, preferably 1.5 to 2.5 parts by weight. In addition to its skin-whitening effect, the essence composition of this invention can also prevent skin aging.

[0030] 1,2-Hexandediol is a solvent-based ingredient. For 100 parts by weight of purified water, it can include 1.0 to 4.0 parts by weight, preferably 1.5 to 2.5 parts by weight. Meeting this weight range, the essence composition of the present invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0031] Hyaluronic acid is a component that can act as a water-soluble thickener. For 100g of purified water, it can include 0.05-0.3g by weight, preferably 0.07-0.15g by weight. Meeting this weight range, the essence composition of the present invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0032] Plant extracts not only reduce skin irritation but also have excellent skin whitening effects. To impart anti-aging effects to the skin, the natural water used, for 100 parts by weight of purified water, can include 5 to 15 parts by weight, preferably 8 to 12 parts by weight. By satisfying this weight range, the skin-whitening essence composition of the present invention not only has skin whitening effects but also helps prevent skin aging.

[0033] Specifically, the plant extract may include one or more of the following: evening primrose hot water extract, evening primrose seed extract, sycamore leaf ethanol extract, and mulberry leaf ethanol extract, preferably including evening primrose hot water extract, evening primrose seed extract, sycamore leaf ethanol extract, and mulberry leaf ethanol extract.

[0034] Evening primrose is a naturalized plant, mostly found near water, roadsides, and wastelands. This is because it has a wine-like aroma and is favored by wild animals. The name "evening primrose" comes from its habit of opening at night to greet the moon. It grows straight, 50 to 90 cm tall, and is covered entirely in fine hairs. The root leaves spread out in a rose-like pattern from the roots, while the stem leaves are staggered, broadly linear, 5 to 15 cm long and 5 to 12 mm wide. The tips are pointed, the base directly touching the stem, the edges are shallowly serrated, and the leaves are dark green with a white midrib. The flowers are yellow, one in each leaf axil, opening at night and withering in the morning, slightly reddish. The fruit is a club-shaped tuber, 2-3 cm long, divided into four parts. The seed oil is used in folk remedies for diabetes, and the seed oil is used as an antipyretic.

[0035] The Chinese parasol tree is a tall tree with leaves growing in winter and belongs to the Sterculiaceae family of honey plants. The red parasol tree, also known as the parasol tree. The original parasol tree was the parasol tree. The original parasol tree of this parasol tree was the parasol tree, so the Chinese character is called the parasol tree. It is about 10 to 15 meters tall and about 60 - 90 centimeters in diameter. The leaves are 15 - 23 centimeters long and 12 - 29 centimeters wide, and grow huge pentagonal leaves facing each other. The underside of the leaf is heart-shaped. The leaf margin is flat, the front of the leaf is almost hairless, and the back has fine hairs. Around May - June, bell-shaped light purple tube flowers bloom on the terminal panicle, with a strong fragrance. The end is irregularly divided into five. The flower is about 6 cm long, light purple, and hairy. The fruit is egg-shaped with a pointed end, the follicle is 3 cm long, and multiple fruits gather together. After maturing in October, it splits into two pieces. The Chinese parasol tree grows fast and the wood can be used after 10 years of planting. The wood has beautiful grain, soft texture, is moisture-resistant, fire-resistant, light and wear-resistant, and is a good material for making furniture such as desks and wardrobes. In the past, people would plant Chinese parasol trees when they had a daughter for the dowry. In addition, the wood has the property of transmitting sound and is used to make musical instruments such as qin, pipa, and gayageum. The echo of the parasol tree is very good, and it is the first tree as a musical instrument material. In a room, the trunk and root bark are called tung bark or white tung bark and are used for hemorrhoids, contusions, sprains, wounds, malignant tumors, etc. The Chinese parasol tree can also be planted as an ornamental tree in the courtyard.

[0036] Mulberry trees are a general term for deciduous trees or shrubs belonging to the genus *Morus* in the family Moraceae. They are native to temperate and subtropical regions, and there are more than 30 species worldwide. Mulberry trees have been considered valuable trees with significant uses since ancient times. There are wild varieties such as the mountain mulberry (*Morus bombycis*), the stone mulberry (*Morus tiliaefolia*), and the Mongolian mulberry (*Morus mongolica*), whose young branches are hairless. Many mulberry trees are planted around houses or in yards. Mulberry trees are cultivated in many varieties for silkworm rearing, and their leaves are used as food for silkworms. The scientific name of the white elephant mulberry, *Morus*, means mulberry tree, and *alba* means white. Its twigs are grayish-brown or grayish-white, with residual hairs that gradually disappear. The leaves are oval, round, or oblong, divided into 3 to 5 sections, 10 cm long, with blunt serrations along the edges and pointed tips. The petioles and veins on the underside of the leaves have small hairs. The mulberry tree (Mulberry arborescens) blooms in June. Male flower spikes hang from unidentified inflorescences drooping from the leaf axils at the base of new branches, while female flower spikes are 5-10 mm long. There is almost no pistil stalk, and the pistil head has two. The seed ovary is hairless, and the fruit ripens in June, turning black. The fruit of the mulberry tree is called mulberry, also known as mulberry fruit, and in Chinese, it is called "heartbreak fruit." Mulberries are about 1.5-2.5 cm in size and resemble grapes. They initially turn from light green to red, becoming a dark reddish-brown mixed with red when fully ripe. Mulberries are sweet and sour, and are often eaten raw, but in the past, they were often used to make wine. Recently, I often make mulberry jam and also frequently eat mulberry greens for extended periods. In traditional Chinese medicine, mulberries are used as a medicinal herb, said to be able to turn gray hair black, enhance energy, and refresh the mind. The root bark, called mulberry bark, is used in some traditional Chinese medicines for its antipyretic, antitussive, diuretic, and anti-swelling properties, and is also believed to have skin-whitening effects, thus it is also used as a cosmetic ingredient. Wood is also used as furniture material, but its utilization rate is not high.

[0037] More specifically, the hot water extract of evening primrose involves drying evening primrose (Oenothra biennis) at 70–90°C, preferably 75–85°C, for 2–4 hours, and then pulverizing it afterward to prepare an evening primrose powder with a particle size of 40–60 mesh, preferably 45–55 mesh. The prepared evening primrose powder is then added to distilled water and mixed, and extracted at 80–85°C, preferably 15–15°C, for 15–25 minutes.

[0038] Furthermore, evening primrose seed extract is prepared by drying evening primrose seeds (Oenothra biennis) at 70–90°C for 2–4 hours, preferably at 75–85°C for 2.5–3.5 hours, followed by pulverizing to a mesh size of 70–90, preferably 75–85. The prepared evening primrose seed powder is then added to a supercritical carbon dioxide extraction apparatus and extracted at 35–55°C, preferably at 40–40 MPa, and preferably at a pressure of 120 MPa for approximately 160 minutes.

[0039] In addition, the ethanol extract of the leaves of the Chinese parasol tree can be obtained by adding the powder of the Chinese parasol tree leaves (Paulownia tomentosa leaf) to ethanol and mixing them together. The seeds are then soaked at a rate of 70-90°C, with the best temperature being 75-85°C, 600-800 rpm, and the best speed being 650-750 rpm for 12-36 hours. It is best to reflux and extract for 20-28 hours. After that, the extract is filtered with filter paper, concentrated to prepare the filtrate, and then freeze-dried.

[0040] In addition, the ethanol extract of mulberry leaves can be prepared by mixing mulberry leaf (Morus alba leaf) powder with ethanol, and then refluxing the seeds at temperatures of 70-90℃ and 75-85℃ and speeds of 600-800 rpm and 650-750 rpm for 12-36 hours and 20-28 hours, respectively. After filtration with filter paper, the filtrate is concentrated under reduced pressure and then freeze-dried.

[0041] Furthermore, the percentage of plant extracts by total weight is as follows: Evening primrose hot water extract 20-40%, ideally 25-35% by weight, more ideally 28-32% by weight; Evening primrose seed extract 20-40% by weight, ideally 25-35% by weight, more ideally 28-32% by weight; Paulownia leaf ethanol extract 10-30% by weight, ideally 15-25%, ideally 18%-22%; Mulberry leaf extract 10%-22%, ideally 18%-22%, ideally 15% by weight; and Mulberry leaf extract 18%-22%. Because these weight percentage ranges are met, the skin-whitening essence composition of the present invention not only has a skin-whitening effect but also helps prevent skin aging.

[0042] The paid ingredient is a component comprising one or more ingredients for use in emulsion formulations, which may include glyceryl benzoate, scouaran, polyglyceryl-6-octanoate, hydroxybenzoate, cocoa-hexanoate / hexanoate and one or more compounds selected from those labeled with the following chemical formula 1, preferably glyceryl benzoate, propionic acid, cocoa-6-hexanoate, hexanoate / hexanoate, hexanoate, hexanoate / hexanoate may be included.

[0043] [Chemical Formula 1]

[0044]

[0045] In the chemical formula 1, R1, R2, R3, R4, R5 and R6 are each independently a C1 to C10 alkoxy group, preferably each independently a C1 to C3 alkoxy group.

[0046] Glyceryl benzoate is a skin-softening agent. For 100g of purified water, it can include 1.0 to 5.0g by weight, preferably 2.0 to 4.0g by weight. This weight range allows the essence composition of the present invention to not only have a skin-whitening effect, but also to prevent skin aging.

[0047] Squalene is a moisturizing agent. For 100g of purified water, it can comprise 2.0 to 7.0g by weight, preferably 3.0 to 5.0g by weight. Meeting this weight range, the serum composition of the present invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0048] Polyglyceryl-6-octastearate is an emulsifier that can be present in 0.5 to 3.0 parts by weight, preferably 0.7 to 1.5 parts by weight, per 100 parts by weight of purified water. This weight range allows the essence composition of the present invention to not only whiten the skin but also prevent skin aging.

[0049] Hydroxyapatite is an emulsifier that can be present in 0.1 to 1.5 parts by weight, preferably 0.3 to 0.7 parts by weight, per 100 parts by weight of purified water. In addition to its skin-whitening effect, the essence composition of this invention can also prevent skin aging.

[0050] Coco-caprylate / caprate is a solvent-like ingredient. For 100 parts by weight of purified water, it may include 0.1 to 1.0 parts by weight, preferably 0.2 to 0.5 parts by weight. Within this weight range, the essence composition of the present invention, which has the skin-whitening effect, not only has a skin-whitening effect but also helps prevent skin aging.

[0051] The compounds represented by Chemical Formula 1 not only reduce skin irritation but also have excellent skin whitening effects. To impart anti-aging effects to the skin, as a compound, it may include 1 to 2 parts by weight (preferably 1.3 to 1.7 parts by weight) for 100 parts by weight of purified water. By satisfying this weight range, the skin-whitening essence composition of the present invention not only has skin whitening effects but also helps prevent skin aging.

[0052] The present invention has been described above with reference to embodiments, but this is merely an example and does not limit the embodiments of the present invention. With ordinary knowledge in the art to which the embodiments of the present invention pertain, various modifications and applications not foreseen above can be seen without departing from the essential characteristics of the present invention. For example, the various components specifically appearing in the embodiments of the present invention can be implemented in other ways. Moreover, differences related to these modifications and applications should be interpreted as including within the scope of the present invention as defined in the appended claims.

[0053] Preparation Example 1: Preparation of Evening Primrose Hot Water Extract

[0054] (1) The washed evening primrose (Oenothra biennis) was dried at 80°C for 3 hours and then pulverized to prepare evening primrose powder with a particle size of 50 mesh.

[0055] (2) The prepared evening primrose powder was mixed with 1L of distilled water and then extracted with hot water at 90°C for 20 minutes using an autoclave to prepare an evening primrose hot water extract.

[0056] Preparation Example 2: Preparation of Evening Primrose Seed Extract

[0057] (1) After washing the evening primrose (Oenothra biennis) seeds, dry them at 80°C for 3 hours and then crush them to prepare evening primrose seed powder with a particle size of 80 mesh.

[0058] (2) After the prepared evening primrose seed powder was put into the supercritical carbon dioxide extraction device, it was extracted for 150 minutes at a temperature of 45°C and a pressure of 30MPa to prepare evening primrose seed extract.

[0059] Preparation Example 3: Preparation of Ethanol Extract from Sycamore Leaves

[0060] 100g of paulownia tomentosa leaf powder was prepared. The prepared paulownia leaf powder was mixed in 500ml of ethanol and extracted by reflux at 80℃ and 700rpm for 24 hours. After filtration with filter paper, the filtrate was concentrated under reduced pressure and then freeze-dried to prepare the ethanol extract of paulownia leaves.

[0061] Preparation Example 4: Preparation of Mulberry Leaf Ethanol Extract

[0062] 100g of mulberry leaf powder was prepared. The prepared mulberry leaf powder was added to 500ml of ethanol and mixed. After extraction by reflux at 80℃ and 700rpm for 24 hours, the mixture was filtered with filter paper. The filtrate was concentrated under reduced pressure and then freeze-dried to prepare mulberry leaf ethanol extract.

[0063] Example 1: Creating a serum composition with skin-whitening effects

[0064] (1) Aqueous phase components were prepared by mixing purified water, sodium peraluminate, methionine, glycerol, glycerides, 1,2-adipic acid glycol, hyaluronic acid, and plant extracts at a temperature of 60°C. The components used to prepare the aqueous phase components were mixed in the weight percentages listed in Table 1 below. Furthermore, for the total weight percentage of plant extracts, a mixture of 30% by weight of evening primrose hot water extract prepared in Preparation Example 1, 30% by weight of evening primrose seed extract prepared in Preparation Example 2, 20% by weight of eucalyptus leaf ethanol extract prepared in Preparation Example 3, and 20% by weight of mulberry leaf ethanol extract prepared in Preparation Example 4 was used.

[0065] (2) An oil phase component was prepared by mixing glyceryl benzoate, squalane, polyglycerol-6 octadecyl ester, hydroxymethylrexate, cocoa-caprit / caprit and compounds labeled with the following chemical formula 1-1 at a temperature of 70°C. At this time, the components used to prepare the oil phase component were mixed in the weight parts listed in Table 1 below.

[0066] (3) At a temperature of 50°C, the aqueous phase component and the oil phase component are uniformly mixed to prepare an essence composition.

[0067] [Chemical Formula 1-1]

[0068]

[0069] In the chemical formula 1-1, R1, R2, R3, R4, R5 and R6 are methyl groups, respectively.

[0070] Table 1

[0071]

[0072] Example 2: Creating a serum composition with skin-whitening effects

[0073] The serum composition was prepared using the same method as in Example 1. However, unlike in Example 1, for 100 parts by weight of purified water, the compound with chemical formula 1-1 was not mixed to a weight of 1.5 parts by weight, and for 100 parts by weight of purified water, the compound with chemical formula 1-1 was mixed to a weight of 0.5 parts by weight, thus finally preparing the serum composition.

[0074] Example 3: Creating a serum composition with skin-whitening effects

[0075] The serum composition was prepared using the same method as in Example 1. However, unlike in Example 1, for 100 parts by weight of purified water, the compound with chemical formula 1-1 was not mixed to a weight of 1.5 parts by weight, and for 100 parts by weight of purified water, the compound with chemical formula 1-1 was mixed to a weight of 2.5 parts by weight, thus preparing the serum composition.

[0076] Example 4: Creating a serum composition with skin-whitening effects

[0077] The essence composition was prepared using the same method as in Example 1. However, unlike in Example 1, for 100 parts by weight of purified water, 10.0 parts by weight of plant extracts were not mixed, and for 100 parts by weight of purified water, 3.0 parts by weight of plant extracts were mixed, thus preparing the essence composition.

[0078] Example 5: Creating a serum composition with skin-whitening effects

[0079] The essence composition was prepared using the same method as in Example 1. However, unlike in Example 1, for 100 parts by weight of purified water, 10.0 parts by weight of plant extracts were not mixed, and for 100 parts by weight of purified water, 17.0 parts by weight of plant extracts were mixed to finally prepare the essence composition.

[0080] Example 6: Creating a serum composition with skin-whitening effects

[0081] The essence composition was prepared using the same method as in Example 1. However, unlike Example 1, for the total weight percentage of plant extracts, a mixture of 30% by weight of evening primrose hot water extract prepared in Preparation Example 1, 30% by weight of evening primrose seed extract prepared in Preparation Example 2, and 40% by weight of sycamore leaf ethanol extract prepared in Preparation Example 3 was used.

[0082] Example 7: Creating a serum composition with skin-whitening effects

[0083] The essence composition was prepared using the same method as in Example 1. However, unlike Example 1, a mixture of 30% by weight of evening primrose hot water extract prepared in Preparation Example 1, 30% by weight of evening primrose seed extract prepared in Preparation Example 2, and 40% by weight of mulberry leaf ethanol extract prepared in Preparation Example 4 was used as the total weight percentage of plant extracts.

[0084] Example 8: Creating a serum composition with skin-whitening effects

[0085] The essence composition was prepared using the same method as in Example 1. However, unlike Example 1, for the total weight percentage of plant extracts, a mixture of 20% evening primrose hot water extract prepared in Preparation Example 1, 20% evening primrose seed extract prepared in Preparation Example 2, 30% sycamore leaf ethanol extract prepared in Preparation Example 3, and 30% mulberry leaf ethanol extract prepared in Preparation Example 4 was used.

[0086] Example 9: Creating a serum composition with skin-whitening effects

[0087] The essence composition was prepared using the same method as in Example 1. However, unlike Example 1, the total weight percentage of the plant extracts was a mixture of 40% by weight of evening primrose hot water extract prepared in Preparation Example 1, 40% by weight of evening primrose seed extract prepared in Preparation Example 2, 10% by weight of sycamore leaf ethanol extract prepared in Preparation Example 3, and 10% by weight of mulberry leaf ethanol extract prepared in Preparation Example 4.

[0088] Comparative Example 1: Manufacturing of an essence composition with skin whitening effect

[0089] (1) Aqueous phase components were prepared by mixing purified water, sodium peraluminate, methionine, glycerol, glycerides, 1,2-adipic acid glycol, hyaluronic acid, and plant extracts at a temperature of 60°C. The components used to prepare the aqueous phase components were mixed in the weight percentages shown in Table 2 below. Furthermore, for the total weight percentage of plant extracts, a mixture of 30% by weight of evening primrose hot water extract prepared in Preparation Example 1, 30% by weight of evening primrose seed extract prepared in Preparation Example 2, 20% by weight of eucalyptus leaf ethanol extract prepared in Preparation Example 3, and 20% by weight of mulberry leaf ethanol extract prepared in Preparation Example 4 was used.

[0090] (2) An oil phase component was prepared by mixing glyceryl benzoate, squalane, polyglycerol-6 octadecyl ester, hydroxymethyl rexate, and cocoa-caprit / caprit at a temperature of 70°C. The components used to prepare the oil phase component were mixed in the weight parts listed in Table 2 below.

[0091] (3) At a temperature of 50°C, the aqueous phase component and the oil phase component are uniformly mixed to prepare an essence composition.

[0092] Table 2

[0093]

[0094] Experimental Example 1: Confirming Antioxidant Effect (DPPH assay)

[0095] To confirm that the serum compositions prepared in Examples 1-9 and Comparative Example 1 each have antioxidant effects that have anti-aging effects, the radial scavenging ability of DPPH was evaluated.

[0096] Specifically, the essence compositions prepared in Examples 1-9 and Comparative Example 1 were each added to a 100-micron DPPH solution at a depth of 50 microns, and reacted under light-shielding conditions at room temperature (25°C) for 15 minutes. The absorbance was measured at 517 nm. As a control group (PC, Positive control), α-tocopherol was used, and the radial elimination energy of DPPH was calculated according to Formula 1 below. The results are shown in Table 3 below.

[0097] [Mathematical Expression 1]

[0098] Inhibition (%) = {1-OD} sample / OD control}×100

[0099] Experiment Example 2: Confirmation of Whitening Effect (Tyrosinase Inhibition Effect)

[0100] To confirm the whitening effect of the essence compositions manufactured in Examples 1-9 and Comparative Example 1, the blocking effect of theanine enzyme was evaluated.

[0101] Specifically, in Examples 1-9 and Comparative Example 1, 80 hectares of 100 mM Sodiumphosphate buffer (pH 6.8) and 40 hectares of Tyrosinase were added to a 40 hectares solution, respectively, and the reaction was carried out at 37°C for 15 minutes. Then, 40 hectares of L-DOPA were added to the reaction solution, and after reacting at 37°C for 9 minutes, the inhibitory effect of theanine enzyme was measured by ELISA at 475 nm. Positive Control was used for nose measurement, and the inhibition rate of tyrosinase was calculated according to the following mathematical formula 2, and the results are shown in Table 3 below:

[0102] [Mathematical Expression 2]

[0103] Tyrosinase inhibition effect (%) = {1-OD sample / OD Control}×100

[0104] Table 3

[0105] the difference Example 1 Example 2 Example 3 Example 4 Example 5 DPPH free radical scavenging capacity (%) 60.4 56.9 60.1 51.5 60.0 Tyrosinase inhibition rate (%) 66.1 63.0 66.1 58.8 65.0 the difference Example 6 Example 7 Example 8 Example 9 Comparative Example 1 DPPH free radical scavenging capacity (%) 58.9 59.4 59.5 59.7 55.5 Tyrosinase inhibition rate (%) 64.0 64.2 64.4 65.1 57.2

[0106] As shown in Table 3, the prepared serum composition in Example 1 was confirmed to have the best antioxidant and whitening effects. Furthermore, the serum composition prepared in Example 3 contained more compounds labeled with Formula 1-1 than the sensor composition prepared in Example 1; however, since the blocking rate of the thiophene inhibitor did not increase, not only was the cost-effectiveness reduced, but the radial elimination energy of DPPH was also decreased.

[0107] Simple variations or modifications of the present invention can be readily implemented by a person with ordinary knowledge in the art, and such variations or modifications can be considered to be included within the scope of the present invention.

Claims

1. A serum composition with skin-whitening effect, comprising an aqueous phase component and an oil phase component, wherein, The aqueous phase components include purified water and plant extracts. The oil phase component includes compounds labeled with the following chemical formula 1, which are essence components with skin whitening effects. [Chemical Formula 1] In the chemical formula 1, R1, R2, R3, R4, R5 and R6 are each independently an alkoxy group from C1 to C10.

2. The serum composition with skin-whitening effect according to claim 1, wherein, The essence composition contains, by weight, 1 to 2 compounds represented by the chemical formula 1, relative to 100 parts by weight of purified water.

3. The serum composition with skin-whitening effect according to claim 1, wherein, The essence composition comprises 5 to 15 parts by weight of plant extract relative to 100 parts by weight of purified water.

4. The serum composition with skin-whitening effect according to claim 3, wherein, The plant extracts include evening primrose hot water extract, evening primrose seed extract, sycamore leaf ethanol extract, and mulberry leaf ethanol extract.

5. The serum composition with skin-whitening effect according to claim 4, wherein, The plant extracts, relative to the total weight, include 20-40% by weight of evening primrose hot water extract, 20-40% by weight of evening primrose seed extract, 10-30% by weight of eucalyptus leaf ethanol extract, and 10-30% by weight of mulberry leaf ethanol extract.

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