A composite vegetable oil fat emulsification system, a preparation method and application thereof

Abstract

The application provides a composite vegetable oil emulsification system, a preparation method and application thereof, and relates to the technical field of cosmetics.The composite vegetable oil emulsification system is composed of the following components in parts by weight: 40-60 parts of white pool rape seed oil, 20-40 parts of water, 5-15 parts of beeswax, 2-4 parts of sodium carbonate, 0.5-1.5 parts of octyldodecanol, 1.2-2.8 parts of agave sisalina leaf and seed oil, 1.2-2.8 parts of cyperus oil and 0.5-1.5 parts of malva sylvestris root extract; a low-temperature saponification reaction method is adopted, primary saponification can be realized at 45-49 DEG C, then secondary reaction is carried out by heating to 65-75 DEG C to obtain a stable emulsification system. The vegetable oil with specific components is the core, is compounded with cyperus oil and malva sylvestris root extract, the composite vegetable oil emulsification system obtained has multiple effects of mild long-acting moisturizing and high-efficiency anti-inflammatory soothing, has high stability, and has small particle size and PDI.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology, specifically relating to a composite plant oil emulsification system, its preparation method, and its application. Background Technology

[0002] Creamy cosmetics or face creams have a thicker texture and provide excellent moisturizing and hydrating effects, keeping the skin hydrated and repairing skin damage. Some functional face creams also have properties such as smoothing acne marks, eliminating scars, fading dark spots, reducing redness, moisturizing and locking in moisture, soothing, and anti-inflammatory effects. They can prevent moisture loss, create a moisturizing barrier for the skin, and have a repairing effect on the skin, thereby activating the skin's moisturizing function, promoting the absorption of effective ingredients, and providing strong moisturizing properties, which can specifically improve the sub-healthy state of the skin.

[0003] However, commercially available cream-based cosmetics primarily achieve their emulsification and cleansing functions through synthetic surfactants or traditional soap bases. Traditional soap-based creams (or cleansing creams) utilize strong alkali for complete saponification, resulting in a high pH value (>9). Long-term use can easily damage the skin barrier, leading to dryness and sensitivity. Creams prepared using emulsifiers obtained through strong alkali saponification reactions may irritate sensitive skin. Furthermore, many natural plant-based active ingredients with excellent repairing effects are easily deactivated in high-heat or strong-alkali processes, thus failing to achieve the multi-functional effects of low irritation, high emulsification, gentle and long-lasting moisturizing, skin barrier repair, and anti-inflammatory soothing.

[0004] The new soap-making method involves heating vegetable oil and an alkaline aqueous phase separately to specific temperatures, then mixing and stirring them. The soap-like substances generated by the saponification reaction act as emulsifiers, reducing the interfacial tension between oil and water, thus forming a stable emulsion. This method uses alkaline substances such as sodium hydroxide, calcium hydroxide, or triethanolamine at temperatures above 70°C for the saponification reaction. The high reaction temperature and the strong alkali result in emulsifiers with strong irritant properties, which are not conducive to soothing the skin. Chinese invention patent CN115969777A describes a corydalis-bletilla polysaccharide gel emulsion and its preparation method, including the following steps: mixing and dissolving bletilla polysaccharide and konjac gum in a solvent to obtain a first mixture; centrifuging the first mixture to obtain a supernatant; uniformly mixing glycerin, triethanolamine, and the supernatant, and maintaining the mixture in a 70°C water bath to obtain an aqueous phase; uniformly mixing corydalis, lavender essential oil, and molten stearic acid to obtain an oil phase; and uniformly mixing the oil phase into the aqueous phase for homogenization and emulsification. Chinese invention patent CN1105852A discloses a skin nutrient and a cosmetic composition containing the skin nutrient. The skin nutrient contains at least one saponified product. The saponification reaction is carried out under alkaline conditions using sodium hydroxide, potassium hydroxide, calcium hydroxide, and triethanolamine as reagents. Saponification products are difficult to form at temperatures below 50°C, making it impossible to obtain a product with uniform and stable properties. Therefore, those skilled in the art generally use a higher temperature of 70°C for the reaction.

[0005] Furthermore, commercially available cream-based cosmetics often contain a large number of chemically irritating ingredients to enhance their moisturizing and anti-inflammatory properties. Prolonged use of these ingredients can actually damage the skin. In addition, the moisturizing, soothing, anti-inflammatory, and repairing effects of most cosmetics are attributed to active extracts, while the properties of the emulsifiers themselves are often overlooked.

[0006] For example, Chinese invention patent CN111407713A discloses a ginseng and deer antler eye ointment and its processing method, which uses more than 40 kinds of plant extracts and more than 10 kinds of moisturizing ingredients, including dipropylene glycol, sorbitol, glycerin, cyclopentamethoxysiloxane, polydimethylsiloxane, sodium hyaluronate, dextran, ginseng root extract, hydrogenated polyisobutylene, glyceryl stearate, coix seed extract, and safflower extract. Chinese invention patent CN114632013A discloses a moisturizing solid, wherein the emollient is one or any combination of hexyl laurate, triglyceride (ethylhexanoate), polydimethylsiloxane, polydimethylsiloxane / vinyl dimethylsiloxane crosspolymer, tocopherol, shea butter, meadowfoam seed oil, and jojoba seed oil; the moisturizer is octyl dodecanol, plantain leaf and artichoke seed oil, sunflower seed oil unsaponifiables, a mixture of lycoperdon flower / leaf / vine extract and tocopherol, glycerin, apple extract, and Chlorella / lupin protein fermentation product; the skin conditioning agent includes pentaerythritol tetra(bis-tert-butylhydroxyhydrocinnamic acid) ester, soluble collagen, carnosine, lemon extract, papain, tremella extract, hydrolyzed yeast protein, cordyceps extract, potato pulp extract, centella asiatica leaf extract, angelica sinensis leaf / stem extract, and magnolia liliiflora extract. In existing technologies, in order to achieve multiple technical effects in cosmetics, a large number of active ingredients are added, but the effect of simplifying the components and achieving synergistic effects among the components has not been achieved. Summary of the Invention

[0007] This invention addresses the problems existing in the prior art by providing a composite plant oil emulsion system, its preparation method, and its applications. This invention employs a low-temperature saponification reaction method, using plant oils with specific components as the core, to obtain a composite plant oil emulsion system that possesses multiple benefits including gentle and long-lasting moisturizing, skin barrier repair, and highly effective anti-inflammatory and soothing effects. The components are simplified, and the emulsion system exhibits high stability, small particle size, and low particle density (PDI).

[0008] To achieve the above objectives, the technical solution adopted by the present invention is as follows: First, the present invention provides a compound plant oil emulsification system, which, by weight, consists of the following components: 40-60 parts of meadowfoam (LIMNANTHES ALBA) seed oil, 20-40 parts of water, 5-15 parts of beeswax, 2-4 parts of sodium carbonate, 0.5-1.5 parts of octyldodecanol, 1.2-2.8 parts of Echium plantagineum seed oil, 1.2-2.8 parts of Cyperus rotundus oil, and 0.5-1.5 parts of Althaea sylvestris root extract.

[0009] Preferably, the composite plant oil emulsification system comprises, by weight, the following components: 45-55 parts meadowfoam seed oil, 25-35 parts water, 8-13 parts beeswax, 2.5-3.5 parts sodium carbonate, 0.8-1.2 parts octyldodecanol, 1.5-2.5 parts plantain leaf and blue thistle seed oil, 1.5-2.5 parts sedge oil and 0.8-1.2 parts marshmallow root extract.

[0010] More preferably, the composite plant oil emulsification system comprises, by weight, the following components: 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain leaf and blue thistle seed oil, 2 parts sedge oil and 1 part marshmallow root extract.

[0011] In this invention, the meadowfoam seed oil contains less than 20% unsaturated fatty acids and more than 80% long-chain fatty acids with C20 or higher.

[0012] Then, the present invention provides a method for preparing the above-mentioned composite vegetable oil emulsion system, comprising the following steps: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 45-49℃, and carry out low-temperature saponification reaction to obtain the primary product of saponification reaction; (2) Mix the primary product of the saponification reaction with beeswax, and heat to 65-75℃ for a secondary reaction to obtain a stable emulsion system A; (3) Emulsion system A is mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0013] Preferably, in step (1), the temperature of the heating is 47-49°C; more preferably, in step (1), the temperature of the heating is 49°C.

[0014] Preferably, in step (1), the low-temperature saponification reaction takes 1-3 hours; more preferably, in step (1), the low-temperature saponification reaction takes 2 hours.

[0015] Preferably, in step (2), the secondary reaction is carried out at a temperature of 68-72°C; more preferably, in step (2), the secondary reaction is carried out at a temperature of 70°C.

[0016] Preferably, in step (2), the secondary reaction has a reaction time of 0.5-2 hours; more preferably, in step (2), the secondary reaction has a reaction time of 1 hour.

[0017] Preferably, in step (1), the low-temperature saponification reaction requires stirring during the reaction process, and the stirring speed is 50-80 rpm; more preferably, the stirring speed is 60 rpm.

[0018] Preferably, in step (2), the secondary reaction requires stirring during the reaction process, and the stirring speed is 50-80 rpm; more preferably, the stirring speed is 60 rpm.

[0019] Preferably, in step (3), the mixing temperature is 45-49°C; more preferably, in step (3), the mixing temperature is 47-49°C; even more preferably, in step (3), the mixing temperature is 49°C.

[0020] Finally, this invention provides the application of the above-mentioned composite plant oil emulsification system in cosmetics that moisturize, soothe, reduce inflammation, and repair the skin barrier.

[0021] Compared with the prior art, the present invention has the following beneficial effects: 1. The composite plant oil emulsification system of this invention employs a low-temperature saponification reaction method, using specific plant oil components as the core, and possesses multiple effects including gentle and long-lasting moisturizing, skin barrier repair, and highly effective anti-inflammatory and soothing properties. Specifically, meadowfoam seed oil and sodium carbonate undergo a low-temperature saponification reaction first, followed by the addition of beeswax and a secondary reaction at 65-75°C. The resulting composite plant oil emulsification system is fine, highly stable, and has a small particle size and PDI. The preparation method of this invention effectively encapsulates components such as plantain leaf and artichoke seed oil, sedge oil, and marshmallow root extract, ensuring they remain active under gentle preparation conditions and do not irritate sensitive skin during use.

[0022] 2. The compound plant oil emulsification system of the present invention has a simplified formula, is pH-friendly to the skin, and can maximize the retention and synergistic enhancement of the efficacy of plant active ingredients. The plant oil, sedge seed oil and marshmallow root extract interact and complement each other, bringing significantly improved moisturizing, anti-inflammatory, skin barrier repair and skin soothing effects. Detailed Implementation

[0023] The following non-limiting embodiments are intended to enable those skilled in the art to gain a more comprehensive understanding of the present invention, but do not limit the invention in any way. The following content is merely an exemplary description of the scope of protection claimed by the present invention, and those skilled in the art can make various changes and modifications to the present invention based on the disclosed content, and such changes should also fall within the scope of protection claimed by the present invention.

[0024] When numerical ranges are given in the embodiments, it should be understood that, unless otherwise stated in the invention, both endpoints of each numerical range and any value between the two endpoints may be selected. Unless otherwise defined, all technical and scientific terms used in this invention have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains.

[0025] The present invention will be further described below by way of specific embodiments. Unless otherwise specified, all chemical reagents used in the embodiments of the present invention are obtained through conventional commercial means.

[0026] In a specific embodiment of the present invention, the meadowfoam seed oil was purchased from Guangzhou Huatu Cosmetics Technology Co., Ltd., with the material name HTMOL MEADOWFOAM SEED OIL; the beeswax was purchased from Nuoxin (Guangzhou) International Trading Co., Ltd., with the product number Cerafumei beeswax 2004; the octyl-dodecyl alcohol was purchased from Guangzhou Zibang Biomedical Co., Ltd., with the product number BINISOPA G20; the plantain leaf and blue thistle seed oil was purchased from Guangzhou Aoxue Biotechnology Co., Ltd., with the material code DEFENSLL; the sedge oil was purchased from Kosme Pharmaceutical (Shanghai) Co., Ltd.; and the grape seed oil was purchased from Limeda (Guangzhou) Chemical Trading Co., Ltd., with the product name grape seed oil. For the above components, products from different manufacturers do not have a significant impact on the efficacy.

[0027] In this invention, the marshmallow root extract can be a commercially available product or a homemade product; in a specific embodiment of this invention, the marshmallow root extract is a homemade product, comprising the following steps: (1) The root of the hollyhock was crushed and then heated with water at 60-68℃ for extraction. The solid and liquid were separated to obtain an aqueous extract. (2) The aqueous extract is concentrated, and then an ethanol solution is added until the volume concentration of ethanol in the system is 75%-85%. The precipitate is allowed to stand and then dried to obtain the okra root extract.

[0028] Basic Example 1: Preparation method of marshmallow root extract (1) The root of the hollyhock was crushed and then heated and stirred with 20 times its weight of water at 65°C for 6 hours. The solid and liquid were separated to obtain the water extract. (2) The aqueous extract was concentrated (relative density 1.25-1.30, 25℃), and then ethanol was added until the volume concentration of ethanol in the system was 80%. The precipitate was allowed to stand and dried to obtain the okra root extract.

[0029] The marshmallow root extract from the basic example 1 was used to prepare the following examples and comparative examples of compound plant oil emulsion systems.

[0030] Example 1 A compound plant oil emulsification system comprises, by weight: 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain leaf and blue thistle seed oil, 2 parts sedge oil and 1 part marshmallow root extract.

[0031] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0032] Example 2 A compound plant oil emulsification system comprises, by weight, 45 parts meadowfoam seed oil, 25 parts water, 8 parts beeswax, 2.5 parts sodium carbonate, 1.2 parts octyldodecanol, 2.5 parts plantain leaf and blue thistle seed oil, 2.5 parts sedge oil and 0.8 parts marshmallow root extract.

[0033] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 47°C, and carry out low-temperature saponification reaction for 3 hours under stirring at 50 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 72°C, and carry out a secondary reaction for 0.5 h under stirring at 50 rpm to obtain a stable emulsion system A; (3) At a temperature of 47°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0034] Example 3 A complex plant oil emulsification system comprises, by weight, 55 parts meadowfoam seed oil, 35 parts water, 13 parts beeswax, 3.5 parts sodium carbonate, 0.8 parts octyldodecyl alcohol, 1.5 parts plantain leaf and blue thistle seed oil, 1.5 parts sedge oil and 1.2 parts marshmallow root extract.

[0035] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 45°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 80 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 68°C, and carry out a second reaction for 2 hours under stirring at 80 rpm to obtain a stable emulsion system A; (3) At a temperature of 45°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0036] Example 4 A compound plant oil emulsification system comprises, by weight: 40 parts meadowfoam seed oil, 20 parts water, 5 parts beeswax, 2 parts sodium carbonate, 1.5 parts octyldodecyl alcohol, 2.8 parts plantain leaf and blue thistle seed oil, 1.2 parts sedge oil and 0.5 parts marshmallow root extract.

[0037] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 47°C, and carry out low-temperature saponification reaction for 3 hours under stirring at 50 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 75°C, and carry out a second reaction for 1 hour under stirring at 50 rpm to obtain a stable emulsion system A. (3) At a temperature of 47°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0038] Example 5 A compound plant oil emulsification system comprises, by weight: 60 parts meadowfoam seed oil, 40 parts water, 15 parts beeswax, 4 parts sodium carbonate, 0.5 parts octyldodecyl alcohol, 1.2 parts plantain leaf and blue thistle seed oil, 2.8 parts sedge oil and 1.5 parts marshmallow root extract.

[0039] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 47°C, and carry out low-temperature saponification reaction for 1 hour under stirring at 50 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 65°C, and carry out a second reaction for 1 hour under stirring at 50 rpm to obtain a stable emulsion system A. (3) At a temperature of 47°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0040] Comparative Example 1 Unlike Example 1, in the compound vegetable oil emulsification system, meadowfoam seed oil is replaced with grape seed oil (obtained by steam distillation and cooling of grape seeds, and separation of the upper oil layer using an oil separator).

[0041] A complex plant oil emulsification system comprises, by weight, 50 parts grape seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain seed oil, 2 parts sedge oil, and 1 part marshmallow root extract.

[0042] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix grape seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction; (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0043] Comparative Example 2 Unlike Example 1, in the compound vegetable oil emulsification system, sedge oil is replaced with argan oil (obtained by physical pressing of argan oil).

[0044] A complex plant oil emulsification system comprises, by weight, 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain leaf and blue thistle seed oil, 2 parts argan oil and 1 part marshmallow root extract.

[0045] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A was mixed with octyl dodecanol, plantago seed oil, argan oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0046] Comparative Example 3 Unlike Example 1, the marshmallow root extract was replaced with astragalus extract. The preparation method of astragalus extract was as follows: Astragalus was pulverized, then heated and stirred with 20 times its weight of water at 65°C for 6 hours. Solid-liquid separation was performed to obtain an aqueous extract. The aqueous extract was concentrated (relative density 1.25-1.30, 25°C), and then ethanol was added until the volume concentration of ethanol in the system reached 80%. The mixture was allowed to stand to obtain a precipitate, which was then dried to obtain the astragalus extract.

[0047] A compound plant oil emulsification system comprises, by weight, 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain leaf and blue thistle seed oil, 2 parts sedge oil and 1 part astragalus extract.

[0048] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and astragalus extract to obtain a complex plant oil emulsion system.

[0049] Comparative Example 4 Unlike Example 1, the components in the compound plant oil emulsion system are different, and it does not contain the components: sedge oil and marshmallow root extract.

[0050] A compound vegetable oil emulsification system comprises, by weight, 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, and 2 parts plantago seed oil.

[0051] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A, octyl dodecanol and plantago seed oil were mixed to obtain a composite plant oil emulsion system.

[0052] Comparative Example 5 Unlike Example 1, the components in the compound plant oil emulsion system are different, and it does not contain the component: sedge oil.

[0053] A complex plant oil emulsification system comprises, by weight, 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain leaf and blue thistle seed oil, and 1 part marshmallow root extract.

[0054] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A was mixed with octyl dodecanol, plantago seed oil and marshmallow root extract to obtain a complex plant oil emulsion system.

[0055] Comparative Example 6 Unlike Example 1, the components in the compound plant oil emulsion system are different, and it does not contain the component: marshmallow root extract.

[0056] A compound vegetable oil emulsification system comprises, by weight, 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain leaf and blue thistle seed oil, and 2 parts sedge oil.

[0057] The preparation method of this composite vegetable oil emulsification system is as follows: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 49°C, and carry out low-temperature saponification reaction for 2 hours under stirring at 60 rpm to obtain the primary product of saponification reaction. (2) Mix the primary product of the saponification reaction with beeswax, heat to 70°C, and carry out a second reaction for 1 hour under stirring at 60 rpm to obtain a stable emulsion system A; (3) At a temperature of 49°C, emulsion system A was mixed with octyl dodecanol, plantain leaf blue thistle seed oil and sedge oil to obtain a composite plant oil emulsion system.

[0058] Comparative Example 7 Unlike Example 1, the weight ratios of meadowfoam seed oil, plantain leaf and blue thistle seed oil, sedge oil, and marshmallow root extract in the compound plant oil emulsification system are different. All other aspects are the same as in Example 1.

[0059] A compound plant oil emulsification system comprises, by weight, 51.5 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2.9 parts plantain leaf and blue thistle seed oil, 0.4 parts sedge oil and 0.2 parts marshmallow root extract.

[0060] Comparative Example 8 Using the saponification reaction temperature and alkaline substance sodium carbonate of Example 1 of this application, and combined with the method of Example 1 of Invention Patent CN1105852A, an emulsion product of meadowfoam seed oil was prepared.

[0061] Add 27g of ethanol to 60g of meadowfoam seed oil and react at 49℃ for 45min; then add 15g of saturated sodium carbonate aqueous solution dropwise at 49℃ for 5min; then raise the temperature to 70℃ and stir at 60rpm for 1h. After the reaction is complete, a mixture is obtained that cannot form an emulsion system.

[0062] Test Example 1: Stability Test Samples: Composite vegetable oil emulsion system products prepared in Examples 1-5.

[0063] Detection method: The average particle size and polydispersity index (PDI) of each sample were measured using a Malvern particle size analyzer. 1 mL of sample was placed in a beaker, and 50 mL of meadowfoam seed oil was added to dilute the sample and shaken well (to avoid multiple scattering effects). The diluted sample was then added to the sample cell of the Malvern particle size analyzer, and the particle size and PDI value of each sample were measured at 25°C. Three parallel measurements were performed, and the average value was taken.

[0064] After placing each diluted sample at 40±2℃ and 75%±5%RH for 2 months, the particle size and polydispersity index were tested again. The stability of the emulsion system was judged from the changes in average particle size and polydispersity index.

[0065] The average particle size and polydispersity index results for each sample are shown in Table 1.

[0066] Table 1

[0067] As can be seen from the results in Table 1, the composite plant oil emulsion system prepared in the embodiments of the present invention has a small average particle size, a low polydispersity index, and a uniform particle size, which is conducive to skin absorption. After two months of high-temperature accelerated testing, the average particle size and polydispersity index showed little change, indicating that the performance is uniform and stable.

[0068] Experiment 2: Anti-inflammatory and soothing effect test Experiment on the effect of LPS (lipopolysaccharide)-induced secretion of inflammatory factors RAW264.7 cells were seeded into well plates and incubated overnight at 37°C in a 5% CO2 incubator. Blank groups, model groups, and sample groups (Example 1-Example 5, Comparative Example 1-Comparative Example 7) were set up. When the cell seeding rate of the well plates reached 50-60%, the samples were processed.

[0069] The blank group was given culture medium without LPS inducer (DMEM medium); the model group was given culture medium containing LPS inducer (1 μg / g); the sample group was given culture medium containing LPS inducer (1 μg / mL) and 1g of emulsion system sample (compound vegetable oil emulsion systems of Examples 1-5 and Comparative Examples 1-7, respectively).

[0070] After adding the samples, the well plates were placed in an incubator (37℃, 5% CO2) for culture. After 12 hours of cell incubation, the cell supernatant was collected, and the levels of inflammatory factors NO and IL-6 were detected using the corresponding ELISA kits. The results are shown in Table 2.

[0071] Table 2

[0072] In Table 2, # and ## This indicates that each group of data has a significant difference compared to the model group. # This indicates that P < 0.05. ## This indicates that P < 0.01; △ and △△ This indicates that the data from each comparative example group are significantly different from those from Example 1 group. △ This indicates that P < 0.05. △△ This indicates that P < 0.01.

[0073] As shown in Table 2, the composite plant oil emulsification system of this invention has a significant inhibitory effect on LPS-induced secretion of NO and IL-6 in macrophages, and its overall improvement effect is superior to that of the individual components in Comparative Examples 4-6. Furthermore, compared to the composite plant oil emulsification systems in Comparative Examples 1-3 where components were replaced, the components in this invention work synergistically and effectively, resulting in enhanced anti-inflammatory efficacy. The appropriate proportions of components in the composite plant oil emulsification system of this invention lead to superior anti-inflammatory efficacy compared to the conventionally formulated Comparative Example 7.

[0074] Test Example 3: Hydrating and Moisturizing Effect Test Sixty-five female participants (aged 20-40 years) with healthy facial skin were randomly divided into 13 groups of 5 volunteers each. Each group used the compound plant oil emulsification system described in Examples 1-5 and Comparative Examples 1-7, respectively. The control group used 5% glycerin by volume.

[0075] Cosmetic product sample: The compound plant oil emulsion system was diluted with 5% glycerin by volume to obtain a cosmetic product containing 10% by mass of the compound plant oil emulsion system.

[0076] Measurement environment: The measurement shall be carried out in a spacious, well-ventilated examination room with stable temperature, humidity and other environmental conditions.

[0077] After washing and drying their faces with the same facial cleanser, test subjects marked 2×2cm test areas on their left and right cheeks and measured the skin moisture content in the test areas. Then, 0.5g of a cosmetic product sample (containing 10% of a compound plant oil emulsion system) was applied to the test areas once in the morning and once in the evening. Test subjects in the blank group applied 0.5g of 5% glycerin to the test areas once in the morning and once in the evening.

[0078] Before using the samples, the skin moisture content was tested using a RealBubeeRBX-916 skin stratum corneum moisture meter. Two weeks after the last use of the samples, the skin moisture content was tested again at 0 min and 60 min. The moisture content results were the average of the skin moisture content of the left and right cheeks of 5 test subjects. The skin moisture content (%) is shown in Table 3.

[0079] Table 3

[0080] In Table 3, # and ## This indicates that the data from each comparative example group showed significant differences compared to the data from Example 1 group. # This indicates that P < 0.05. ## This indicates that P < 0.01.

[0081] As shown in Table 3, the composite plant oil emulsification system of the present invention exhibits excellent moisturizing effects, significantly superior to the comparative examples. The glycerin in the blank group showed limited moisturizing performance; the skin moisture content 60 minutes after the last application did not change significantly compared to before application, indicating that glycerin had little impact on improving skin moisture content. Changes in the components of meadowfoam seed oil, sedge oil, and astragalus extract in Comparative Examples 1-3 all resulted in varying degrees of decrease in moisturizing ability, with skin moisture content significantly lower than in the example group. The absence of components in Comparative Examples 4-6 disrupted the synergistic effect between components, particularly the absence of sedge oil and marshmallow root extract, leading to a highly significant decrease in moisturizing performance. Changes in the component ratios in Comparative Example 7 resulted in a decrease in moisturizing effect.

[0082] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, and is not intended to limit the scope of protection of the present invention. Simple modifications or equivalent substitutions made by those skilled in the art to the technical solution of the present invention do not depart from the essence and scope of the technical solution of the present invention.

Claims

1. A composite vegetable oil emulsification system, characterized in that, By weight, it consists of the following components: 40-60 parts meadowfoam seed oil, 20-40 parts water, 5-15 parts beeswax, 2-4 parts sodium carbonate, 0.5-1.5 parts octyldodecanol, 1.2-2.8 parts plantain leaf and blue thistle seed oil, 1.2-2.8 parts sedge oil and 0.5-1.5 parts marshmallow root extract.

2. The composite vegetable oil emulsification system according to claim 1, characterized in that, By weight, it consists of the following components: 45-55 parts meadowfoam seed oil, 25-35 parts water, 8-13 parts beeswax, 2.5-3.5 parts sodium carbonate, 0.8-1.2 parts octyldodecanol, 1.5-2.5 parts plantain leaf and blue thistle seed oil, 1.5-2.5 parts sedge oil and 0.8-1.2 parts marshmallow root extract.

3. The composite vegetable oil emulsification system according to claim 2, characterized in that, By weight, it consists of the following components: 50 parts meadowfoam seed oil, 30 parts water, 10 parts beeswax, 3 parts sodium carbonate, 1 part octyldodecyl alcohol, 2 parts plantain seed oil, 2 parts sedge oil and 1 part marshmallow root extract.

4. The composite vegetable oil emulsification system according to any one of claims 1-3, characterized in that, The meadowfoam seed oil contains less than 20% unsaturated fatty acids and more than 80% long-chain fatty acids with C20 or higher.

5. The method for preparing the composite vegetable oil emulsification system according to any one of claims 1-4, characterized in that, Including the following steps: (1) Mix meadowfoam seed oil with water and sodium carbonate, heat to 45-49℃, and carry out low-temperature saponification reaction to obtain the primary product of saponification reaction; (2) Mix the primary product of the saponification reaction with beeswax, and heat to 65-75℃ for a secondary reaction to obtain a stable emulsion system A; (3) Emulsion system A is mixed with octyl dodecanol, plantain leaf blue thistle seed oil, sedge oil and marshmallow root extract to obtain a complex plant oil emulsion system.

6. The preparation method according to claim 5, characterized in that, In step (1), the temperature for heating is 47-49℃; in step (1), the time for the low-temperature saponification reaction is 1-3h.

7. The preparation method according to claim 5, characterized in that, In step (2), the secondary reaction is carried out at a temperature of 68-72℃; In step (2), the secondary reaction takes 0.5-2 hours.

8. The preparation method according to claim 5, characterized in that, In step (1), the low-temperature saponification reaction requires stirring during the reaction process, and the stirring speed is 50-80 rpm; In step (2), the secondary reaction requires stirring during the reaction process, with a stirring speed of 50-80 rpm.

9. The preparation method according to claim 5, characterized in that, In step (3), the mixing temperature is 45-49℃.

10. The application of the composite plant oil emulsification system according to any one of claims 1-4 in cosmetics that moisturize, soothe, reduce inflammation, and repair the skin barrier.

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