A traditional chinese medicine permeation treatment device for kidney disease

Abstract

This application relates to the technical field of kidney disease, and more particularly to a traditional Chinese medicine (TCM) device for the permeation therapy of kidney disease. The device includes a housing, a fixed plate, and a floating mechanism. The fixed plate is disposed on the inner wall of the housing. Multiple floating mechanisms are arranged in a circular array on the fixed plate. Each floating mechanism includes an ultrasonically conductive silicone pad, a limiting ring, a limiting groove, a first vibrating head, a guide ring, a guide cylinder, and a first spring. The ultrasonically conductive silicone pad is disposed inside the fixed plate, and the limiting ring is disposed on the outer wall of the ultrasonically conductive silicone pad. This embodiment of the TCM device for the permeation therapy of kidney disease utilizes a floating mechanism. Multiple floating mechanisms are arranged in a circular array, each group equipped with an ultrasonically conductive silicone pad, a first vibrating head, a guide cylinder, and a first spring. This allows for slight axial floating, conforming to the physiological curve of the human lumbar region.

Description

Technical Field

[0001] This application relates to the technical field of kidney diseases, and more particularly to a traditional Chinese medicine permeation therapy device for kidney diseases. Background Technology

[0002] In Traditional Chinese Medicine (TCM), kidney disease is often categorized under terms such as "edema," "kidney fatigue," and "urinary tract infection." Its core pathogenesis is typically spleen and kidney deficiency, internal accumulation of dampness and turbidity, and blood stasis. Clinical treatment often focuses on warming the spleen and tonifying yang, promoting blood circulation and removing blood stasis, and eliminating dampness and toxins. TCM external therapy devices, which utilize herbal penetration therapy, avoid the absorption losses and liver burden associated with oral medications through the gastrointestinal tract. By directly applying medication to the kidney area and transmitting it to the lesion via the meridians, it has become an important adjunctive treatment for kidney disease.

[0003] Currently, traditional infiltration therapy devices often use rigid, fixed structures for their ultrasound transmission and electrode coupling components, making it difficult to adapt to individual differences in the physiological curvature of the lumbar region among patients. When the patient's position changes slightly or when breathing causes abdominal movement, gaps can easily form at the rigid contact surfaces, resulting in ultrasound energy attenuation and uneven drug penetration, severely affecting the treatment effect. Summary of the Invention

[0004] This application aims to at least partially address one of the technical problems in the related art.

[0005] One objective of this application is to provide a traditional Chinese medicine transdermal therapy device for kidney disease. Through the configuration of a floating mechanism, multiple floating mechanisms are arranged in a ring array. Each group is equipped with an ultrasonic conductive silicone pad, a first vibrating head, a guide cylinder, and a first spring. It can float slightly along the axial direction, conforming to the physiological curve of the human waist, and adaptively adjusting the contact pressure between each treatment point and the skin surface. This ensures uniform electric field distribution and consistent penetration depth, avoiding gaps between the ultrasonic conductive silicone pad and the skin, which would lead to ultrasonic energy attenuation and electric field distortion. The ultrasonic conductive silicone pad, along with the second positive electrode and the second negative electrode, are tightly attached to the Shenshu acupoint area, achieving efficient transdermal penetration of traditional Chinese medicine ions under the dual drive of ultrasonic cavitation effect and directional electric field.

[0006] To achieve the above objectives, the first aspect of this application proposes a traditional Chinese medicine permeation therapy device for kidney disease, comprising a device shell, a fixed plate, and a floating mechanism. The fixed plate is disposed on the inner wall of the device shell. Multiple floating mechanisms are arranged in a circular array on the fixed plate. Each floating mechanism includes an ultrasonic conductive silicone pad, a limiting ring, a limiting groove, a first vibrating head, a guide ring, a guide cylinder, and a first spring. The ultrasonic conductive silicone pad is disposed inside the fixed plate, the limiting ring is disposed on the outer wall of the ultrasonic conductive silicone pad, and the fixed plate has a limiting groove adapted to the limiting ring. The first vibrating head is disposed on the ultrasonic conductive silicone pad, the guide ring is disposed on the outer wall of the first vibrating head, the guide cylinder is disposed on the fixed plate, and the first spring is disposed inside the guide cylinder, with one end of the first spring connected to the guide ring and the other end of the first spring connected to the guide cylinder.

[0007] In addition, the traditional Chinese medicine permeation therapy device for kidney disease proposed in this application may also have the following additional technical features: In one embodiment of this application, the device further includes a fixing member, an electrode coupling assembly, a switching mechanism, a processing mechanism, and a sealing member. The fixing member is disposed on the outer wall of the device housing, the electrode coupling assembly is disposed on the bottom wall of the fixing plate, the switching mechanism is disposed on the inner wall of the device housing, the processing mechanism is disposed on the bottom wall of the switching mechanism, and the sealing member is disposed on the device housing.

[0008] In one embodiment of this application, the electrode coupling assembly includes an insulating layer, a first positive electrode, a first negative electrode, a drug-conducting cotton, a second positive electrode, and a second negative electrode. The insulating layer is disposed on the bottom wall of the fixing plate. The first positive electrode and the first negative electrode are sequentially disposed in corresponding slots of the insulating layer. The drug-conducting cotton is disposed within the insulating layer. The second positive electrode is disposed on the outer wall of the ultrasonic conductive silicone pad, and the second negative electrode is disposed within the ultrasonic conductive silicone pad.

[0009] In one embodiment of this application, the fastener includes a first connecting strap, a second connecting strap, and a third connecting strap, wherein one end of the first connecting strap is connected to the device housing, and the other end of the first connecting strap is connected to another device housing; one end of the second connecting strap is connected to the device housing, and one end of the third connecting strap is connected to the other end of the second connecting strap, and the other end of the third connecting strap is connected to another device housing.

[0010] In one embodiment of this application, the switching mechanism includes a medicine storage plate, a partition plate, a first connecting pipe, a conveying component, a second connecting pipe, a first solenoid valve, a second solenoid valve, and a protective component. The medicine storage plate is disposed on the inner wall of the device housing, the partition plate is disposed on the medicine storage plate, one end of the first connecting pipe is connected to the medicine storage plate, and the input end of the conveying component is connected to the other end of the first connecting pipe. One end of the second connecting pipe is connected to the medicine storage plate, and the other end of the second connecting pipe is connected to the input end of the conveying component. One end of the protective component is connected to the output end of the conveying component.

[0011] In one embodiment of this application, the protective component includes a protective tube, a spring, a sealing block, and a guide post. One end of the protective tube is connected to the output end of the conveying component. The spring is disposed inside the protective tube, and one end of the spring is connected to the protective tube. The sealing block is connected to the other end of the spring. The guide post is disposed inside the protective tube, and one end of the guide post is connected to the sealing block.

[0012] In one embodiment of this application, the processing mechanism includes a heating plate, a second vibrating head, a signal receiver, a controller, and a stirring component. Two heating plates are provided, symmetrically arranged on the bottom wall of the medicine storage plate about the length axis of the partition plate. Two second vibrating heads are provided, symmetrically arranged on the bottom wall of the medicine storage plate about the length axis of the partition plate. The signal receiver is disposed on a fixed plate, the controller is disposed on the fixed plate, and the stirring component is disposed on the bottom wall of the medicine storage plate.

[0013] In one embodiment of this application, the seal includes a sealing cap and a sealing gasket, wherein the sealing cap is threadedly connected to the housing of the device, and the sealing gasket is disposed on the bottom wall of the sealing cap.

[0014] In one embodiment of this application, the limiting ring and the guide cylinder are cylindrical structures, and the outer wall of the limiting ring slides in conjunction with the inner wall of the guide cylinder.

[0015] In one embodiment of this application, the stirring element includes a micro magnetic stirrer and a stir bar, wherein two micro magnetic stirrers are provided, and the two micro magnetic stirrers are symmetrically arranged on the bottom wall of the medicine storage plate about the width central axis of the partition plate, and the stir bar is symmetrically arranged on the medicine storage plate about the width central axis of the partition plate.

[0016] In one embodiment of this application, the sealing assembly includes a sealing cap, a sealing ring, a handle, and a guide, wherein the sealing cap is disposed on the device housing, the sealing ring is disposed on the bottom wall of the sealing cap, the handle is disposed on the sealing cap, and the guide is disposed on the bottom wall of the sealing cap.

[0017] In one embodiment of this application, the guide includes a guide block, wherein the guide block is disposed on the bottom wall of the sealing cover, and a guide groove adapted to the guide block is formed on the outer wall of the device housing.

[0018] The traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application has the following beneficial effects: 1. Multiple floating mechanisms are arranged in a ring array. Each group is equipped with an ultrasonic conductive silicone pad, a first vibrating head, a guide cylinder, and a first spring. It can float slightly along the axis to conform to the physiological curve of the human waist and adaptively adjust the contact pressure between each treatment point and the skin surface to ensure uniform electric field distribution and consistent penetration depth. This avoids gaps between the ultrasonic conductive silicone pad and the skin, which would lead to ultrasonic energy attenuation and electric field distortion. It also ensures that the ultrasonic conductive silicone pad, the second positive electrode, and the second negative electrode are in close contact with the Shenshu acupoint area, achieving efficient transdermal penetration of Chinese medicine ions under the dual drive of ultrasonic cavitation effect and directional electric field.

[0019] 2. It adopts a focused ultrasonic transducer in combination with a medical ultrasonic conductive silicone pad of specific hardness to ensure efficient transmission of ultrasonic energy while improving wearing comfort and avoiding skin damage; the ultrasonic cavitation effect opens reversible microchannels in the skin, and with the low-voltage DC electric field, it can achieve non-invasive, efficient, and deep targeted drug delivery.

[0020] 3. The medicine storage plate is divided into two independent chambers, which can store different Chinese medicine liquids such as warming and tonifying the kidney and promoting blood circulation. The formula can be quickly switched without interrupting treatment and without cross-contamination through solenoid valves and peristaltic pumps, which greatly improves the flexibility of clinical use.

[0021] 4. Through constant temperature heating, ultrasonic micronization and crushing, and magnetic stirring, the Chinese medicine particles are refined, the viscosity of the medicine solution is reduced, and sedimentation and stratification are prevented, so that the drug concentration is more uniform and the dissolution rate of effective ingredients is higher, thereby further improving the drug penetration efficiency and therapeutic effect.

[0022] 5. The controller has built-in PID temperature control and adaptive power adjustment, which can monitor and dynamically adjust parameters such as temperature, power, and speed in real time to ensure a stable and reliable treatment process. It is easy to operate, reduces the burden on medical staff and patients, and is suitable for clinical promotion and home rehabilitation.

[0023] Additional aspects and advantages of this application will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of this application. Attached Figure Description

[0024] The above and / or additional aspects and advantages of this application will become apparent and readily understood from the following description of the embodiments taken in conjunction with the accompanying drawings, wherein: Figure 1 This is a schematic diagram of the overall structure of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 2 This is an internal schematic diagram of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 3 This is a schematic diagram of the floating mechanism structure of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 4 This is a schematic diagram of the switching mechanism of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 5 This is a schematic diagram of the protective component of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 6 This is a schematic diagram of the processing mechanism of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 7 This is a schematic diagram of the sealing assembly structure of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application; Figure 8 This is a block diagram of a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application.

[0025] As shown in the figure: 1. Device housing; 2. Fixing component; 21. First connecting belt; 22. Second connecting belt; 23. Third connecting belt; 3. Fixing plate; 4. Floating mechanism; 41. Ultrasonic conductive silicone pad; 42. Limiting ring; 43. Limiting groove; 44. First vibrator head; 45. Guide ring; 46. Guide cylinder; 47. First spring; 5. Electrode coupling assembly; 51. Insulating layer; 52. First positive electrode; 53. First negative electrode; 54. Drug-conducting cotton; 55. Second positive electrode; 56. Second negative electrode; 6. Switching machine Structure; 61. Storage plate; 62. Divider plate; 63. First connecting pipe; 64. Conveying component; 65. Second connecting pipe; 66. First solenoid valve; 67. Second solenoid valve; 7. Protective component; 71. Protective pipe; 72. Second spring; 73. Sealing block; 74. Guide column; 8. Processing mechanism; 81. Heating plate; 82. Second vibrating head; 83. Signal receiver; 84. Controller; 85. Stirring component; 851. Miniature magnetic stirrer; 852. Stirring element; 9. Sealing component; 91. Sealing cover; 92. Sealing gasket. Detailed Implementation

[0026] The embodiments of this application are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain this application, and should not be construed as limiting this application.

[0027] The following description, in conjunction with the accompanying drawings, describes a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application.

[0028] The traditional Chinese medicine transdermal therapy device provided in this application embodiment can be applied in the treatment of kidney disease to achieve efficient transdermal penetration of traditional Chinese medicine ions under the dual drive of ultrasonic cavitation effect and directional electric field.

[0029] like Figures 1-8 As shown in the figure, a traditional Chinese medicine permeation therapy device for kidney disease according to an embodiment of this application includes: a device shell 1, a fixing plate 3, and a floating mechanism 4.

[0030] The fixed plate 3 is installed on the inner wall of the outer shell 1 of the device; multiple floating mechanisms 4 are provided, and the multiple floating mechanisms 4 are arranged in a ring array on the fixed plate 3.

[0031] The floating mechanism 4 includes an ultrasonic conductive silicone pad 41, a limiting ring 42, a limiting groove 43, a first vibrating head 44, a guide ring 45, a guide cylinder 46, and a first spring 47.

[0032] The ultrasonic conductive silicone pad 41 is disposed inside the fixed plate 3; the limiting ring 42 is disposed on the outer wall of the ultrasonic conductive silicone pad 41; the fixed plate 3 is provided with a limiting groove 43 that is adapted to the limiting ring 42; the first vibrating head 44 is disposed on the ultrasonic conductive silicone pad 41; the guide ring 45 is disposed on the outer wall of the first vibrating head 44; the guide cylinder 46 is disposed on the fixed plate 3; the first spring 47 is disposed inside the guide cylinder 46, and one end of the first spring 47 is connected to the guide ring 45, and the other end of the first spring 47 is connected to the guide cylinder 46.

[0033] It should be noted that the first transducer 44 described in this embodiment is a commercially available focused ultrasound transducer, whose operating frequency is usually set in the range of 25kHz to 42kHz. This frequency range can effectively penetrate the stratum corneum of human skin, and while maintaining the integrity of the epidermis, it forms drug penetration channels in the dermis and subcutaneous tissue. When the first transducer 44 is activated, the mechanical vibration it generates is transmitted to the surface of human skin through the ultrasonic conductive silicone pad 41. By utilizing the cavitation effect and mechanical effect of ultrasound, the intercellular spaces of skin cells are increased and the permeability of the cell membrane is enhanced, thereby significantly reducing the resistance of drug molecules to penetrate the skin barrier. Since its structure and principle are well known, they will not be described in detail here.

[0034] It should also be noted that the ultrasonic conductive silicone pad 41 described in this embodiment is preferably made of medical-grade high-purity silicone material. The hardness range of medical-grade high-purity silicone material can ensure good acoustic impedance matching, so that ultrasonic energy can be effectively transmitted to the skin tissue, and can also provide a soft and comfortable fit, avoiding pressure damage to the patient's skin during long-term treatment.

[0035] Specifically, when a patient needs to undergo traditional Chinese medicine permeation therapy for kidney disease, the outer shell 1 of the device is first worn on the patient's kidney area at the waist via the fastener 2.

[0036] Subsequently, the switching mechanism 6 is activated to deliver the Chinese medicine liquid that matches the patient's condition to the cotton swab 54, so that the cotton swab 54 is fully soaked with the medicine liquid and maintains appropriate humidity.

[0037] Next, the electrode coupling assembly 5 and the first transducer 44 are activated. The electrode coupling assembly 5 forms an electro-closed circuit in the kidney area of ​​the patient's waist. The local skin tissue is stimulated by low-frequency pulsed current and low-voltage DC electric field, which dilates the pores and increases the permeability of capillaries, creating favorable physiological conditions for drug penetration. Meanwhile, the ultrasonic vibration generated by the first transducer 44 acts on the skin surface through the ultrasonic conductive silicone pad 41. Under the synergistic effect of the cavitation effect and mechanical effect of the ultrasound, the gap between skin cells is further increased. Drug molecules are accelerated to penetrate into the deep tissue under the dual action of electric field driving force and ultrasonic vibration, and finally reach the kidney lesion area to exert a therapeutic effect.

[0038] During the process of wearing the device shell 1 through the fastener 2, the multiple floating mechanisms 4 arranged in a ring array on the fixing plate 3 can adaptively adjust according to the physiological curve of the patient's waist.

[0039] Specifically, since the human waist is not a completely flat plane, but has natural physiological curvature and individual differences, when the patient's waist comes into contact with the ultrasonic conductive silicone pad 41, the ultrasonic conductive silicone pad 41 in each floating mechanism 4 moves towards the first vibrating head 44. During the movement of the first vibrating head 44, the guide ring 45 moves synchronously within the guide cylinder 46. During the movement of the guide ring 45, the first spring 47 is compressed. The first spring 47 will produce different degrees of elastic deformation according to the magnitude of the contact pressure, so that the ultrasonic conductive silicone pad 41 moves slightly along the axial direction under the limiting action of the guide cylinder 46. This achieves uniform contact between multiple ultrasonic conductive silicone pads 41 and the patient's waist skin, avoiding gaps or poor contact between some ultrasonic conductive silicone pads 41 and the skin due to physiological curvature and individual differences, which would lead to uneven transmission of ultrasonic energy and affect the drug penetration effect.

[0040] Meanwhile, by setting up multiple floating mechanisms 4 arranged in a ring array, the ultrasonic vibrations generated by multiple first transducers 44 can form a multi-focal superposition effect, creating a relatively uniform energy distribution field in the patient's lumbar kidney area, effectively expanding the treatment area for drug penetration, avoiding local overheating or insufficient energy caused by single-point energy concentration, and improving the overall safety and effectiveness of the treatment.

[0041] Furthermore, thanks to the first spring 47, when the patient removes the device housing 1, the first spring 47 can quickly rebound and reset, driving the guide ring 45 and the first vibrating head 44 back to their initial positions, so that the ultrasound conduction silicone pad 41 protrudes again from the surface of the fixing plate 3, preparing for the next treatment and ensuring that the device has good reusability and ease of operation.

[0042] like Figure 1 , Figure 3 , Figure 4 , Figure 5 , Figure 6 and Figure 7 As shown, in one embodiment of this application, it also includes a fixing member 2, an electrode coupling assembly 5, a switching mechanism 6, a processing mechanism 8, and a sealing member 9.

[0043] The fixing component 2 is installed on the outer wall of the device housing 1; the electrode coupling assembly 5 is installed on the bottom wall of the fixing plate 3; the switching mechanism 6 is installed on the inner wall of the device housing 1; the processing mechanism 8 is installed on the bottom wall of the switching mechanism 6; and the sealing component 9 is installed on the device housing 1.

[0044] Specifically, when a patient needs to undergo traditional Chinese medicine permeation therapy for kidney disease, the outer shell 1 of the device is first worn on the patient's kidney area at the waist via the fastener 2.

[0045] Subsequently, the switching mechanism 6 is activated to deliver the Chinese medicine liquid that matches the patient's condition to the cotton swab 54, so that the cotton swab 54 is fully soaked with the medicine liquid and maintains appropriate humidity.

[0046] Next, the electrode coupling assembly 5 and the first transducer 44 are activated. The electrode coupling assembly 5 forms an electro-closed circuit in the kidney area of ​​the patient's waist. The local skin tissue is stimulated by low-frequency pulsed current and low-voltage DC electric field, which dilates the pores and increases the permeability of capillaries, creating favorable physiological conditions for drug penetration. Meanwhile, the ultrasonic vibration generated by the first transducer 44 acts on the skin surface through the ultrasonic conductive silicone pad 41. Under the synergistic effect of the cavitation effect and mechanical effect of the ultrasound, the gap between skin cells is further increased. Drug molecules are accelerated to penetrate into the deep tissue under the dual action of electric field driving force and ultrasonic vibration, and finally reach the kidney lesion area to exert a therapeutic effect.

[0047] Meanwhile, the processing unit 8 can perform pretreatment operations such as heating and vibration stirring of the liquid medicine to ensure that the liquid medicine is in the best physical state.

[0048] The sealing element 9 is used to ensure the airtightness of the device and prevent leakage of the medicine and external contamination.

[0049] like Figure 3 As shown, in one embodiment of this application, the electrode coupling assembly 5 includes an insulating isolation layer 51, a first positive electrode 52, a first negative electrode 53, a drug-conducting cotton 54, a second positive electrode 55, and a second negative electrode 56.

[0050] The insulating isolation layer 51 is disposed on the bottom wall of the fixing plate 3; the first positive electrode 52 and the first negative electrode 53 are disposed in the corresponding slots of the insulating isolation layer 51 in sequence; the drug-conducting cotton 54 is disposed inside the insulating isolation layer 51; the second positive electrode 55 is disposed on the outer wall of the ultrasonic conducting silicone pad 41; and the second negative electrode 56 is disposed inside the ultrasonic conducting silicone pad 41.

[0051] It should be noted that, in this embodiment, the first positive electrode 52 and the first negative electrode 53 constitute the first set of iontophoresis electrode pairs, used for superficial meridian dredging. The superficial meridian dredging electrode is used to output low-frequency pulse electrical signals to electrically stimulate acupoints and meridians in the kidney area, thereby dredging the meridians, dilating local microvessels, reducing skin impedance, and establishing a biological channel for deep drug penetration. Subsequently, the second positive electrode 55 and the second negative electrode 56 constitute the second set of iontophoresis electrode pairs, used for deep targeted penetration. The deep targeted penetration electrode is used to apply a low-voltage DC electric field to form a closed targeted electric field in the local area of ​​the penetration head, driving the active ingredients of traditional Chinese medicine to penetrate the skin in a directional manner under the action of the electric field force, thereby achieving deep targeted drug penetration. Specifically, when performing superficial meridian dredging on a patient, the first set of iontophoresis electrode pairs, namely the first positive electrode 52 and the first negative electrode 53, are activated. The two are completely isolated by an insulating layer 51 to avoid short circuits. At the same time, a low-frequency pulse electrical signal is output to continuously stimulate the core acupoints in the kidney area, such as the Shenshu acupoint and the Mingmen acupoint. The stimulation intensity is such that the patient experiences a noticeable soreness and distension but no stinging or discomfort. The stimulation lasts for 5 to 10 minutes. This stage mainly achieves the functions of dredging meridians, harmonizing qi and blood, expanding the local capillary network, and significantly reducing the resistance of the stratum corneum of the skin, creating favorable biophysical conditions for subsequent drug penetration.

[0052] After the first set of electrodes has been used, the first set of iontophoresis electrode pairs is turned off, and the second set of iontophoresis electrode pairs, namely the second positive electrode 55 and the second negative electrode 56, is started. The two are completely isolated by the ultrasonic conductive silicone pad 42 to avoid short circuits. A low-voltage DC electric field is applied, and the first transducer 44 is turned on at the same time. The ultrasonic action and the DC electric field form a synergistic effect. Under the dual action of electric field force and ultrasonic mechanical vibration, the active ingredients of traditional Chinese medicine penetrate the skin barrier in a directional manner and reach the kidney lesion area directly. The duration of a single treatment is set to 20 to 30 minutes. During the treatment, the electric field strength and ultrasonic power can be adjusted in real time according to the patient's tolerance.

[0053] When the first set of electrodes is working, the traditional Chinese medicine suspension in the drug-conducting cotton 54 begins to undergo directional migration under the assistance of a low-frequency pulsed electric field. Some small molecule active ingredients initially penetrate the stratum corneum with the help of the electric field driving force. At the same time, the local microvascular dilation caused by electrical stimulation increases the blood supply to the area where the drug solution contacts the skin, the temperature of the drug solution rises slowly, the viscosity decreases accordingly, and the fluidity is improved, thus reserving a sufficient drug concentration gradient for the subsequent deep penetration stage.

[0054] When the treatment enters the second stage, after the second set of iontophoresis electrode pairs is activated, the DC electric field formed between the second positive electrode 55 and the second negative electrode 56 and the ultrasonic field generated by the first transducer 44 form a coupling area at the interface between the drug-conducting cotton 54 and the skin. At this time, the ultrasonic conductive silicone pad 42 efficiently transmits ultrasonic energy to the skin tissue. The cavitation effect of the ultrasound generates microjets and a local high-temperature and high-pressure microenvironment in the intercellular spaces of the stratum corneum, causing instantaneous disorder of the lipid bilayer structure and forming reversible microchannels. At the same time, the DC electric field applies directional Coulomb forces to the charged ions and polar molecules in the active ingredients of the traditional Chinese medicine, driving them to migrate along the direction of the electric field. The mechanical vibration of the ultrasound further reduces the molecular diffusion resistance. The synergistic effect of the two increases the drug penetration rate, enabling drug molecules to overcome the skin barrier and achieve deep delivery from the epidermis to the dermis and even the subcutaneous tissue.

[0055] like Figure 1 As shown, in one embodiment of this application, the fastener 2 includes a first connecting strap 21, a second connecting strap 22, and a third connecting strap 23.

[0056] One end of the first connecting strap 21 is connected to the device housing 1, and the other end of the first connecting strap 21 is connected to another device housing 1. One end of the second connecting strap 22 is connected to the device housing 1, and one end of the third connecting strap 23 is connected to the other end of the second connecting strap 22, and the other end of the third connecting strap 23 is connected to another device housing 1.

[0057] It should be noted that the first connecting strap 21, the second connecting strap 22 and the third connecting strap 23 described in this embodiment are common buckle-type elastic straps on the market, and are equipped with an adjustable length buckling structure, which can be flexibly adjusted according to the patient's waist size to ensure that the device is neither too tight and uncomfortable during wearing, nor too loose and prone to displacement or falling off. Since its structure and principle are well known, they will not be described in detail here.

[0058] Specifically, the outer walls of the two device housings 1 are respectively provided with a first connecting strap 21, a second connecting strap 22 and a third connecting strap 23. The first connecting strap 21, the second connecting strap 22 and the third connecting strap 23 are connected by buckles. The length of the connecting straps can be adjusted by an adjusting member to meet the wearing needs of patients of different body types.

[0059] like Figure 4 and Figure 5 As shown, in one embodiment of this application, the switching mechanism 6 includes a medicine storage plate 61, a partition plate 62, a first connecting pipe 63, a conveying component 64, a second connecting pipe 65, a first solenoid valve 66, a second solenoid valve 67, and a protective component 7.

[0060] The medicine storage plate 61 is installed on the inner wall of the outer shell 1 of the device, the partition plate 62 is installed on the medicine storage plate 61, one end of the first connecting pipe 63 is connected to the medicine storage plate 61, and the input end of the conveying component 64 is connected to the other end of the first connecting pipe 63, one end of the second connecting pipe 65 is connected to the medicine storage plate 61, and the other end of the second connecting pipe 65 is connected to the input end of the conveying component 64, and one end of the protective component 7 is connected to the output end of the conveying component 64.

[0061] It should be noted that the delivery component 64 described in this embodiment is a commercially available miniature peristaltic pump, which features precise and controllable flow rate, smooth and pulse-free delivery, and adaptability to different viscosities of medicinal liquids. It can be steplessly adjusted according to treatment needs. When the delivery component 64 (miniature peristaltic pump) is activated, it can quantitatively extract the traditional Chinese medicine liquid from the corresponding chamber of the medicine storage plate 61 through the first connecting pipe 63 or the second connecting pipe 65, and deliver it to the drug-guiding cotton 54 through the protective component 7, thereby achieving precise supply of the medicine liquid. Since its structure and principle are well known, they will not be described in detail here.

[0062] It should also be noted that the first solenoid valve 66 and the second solenoid valve 67 described in this embodiment are respectively installed on the first connecting pipe 63 and the second connecting pipe 65 to control the on / off state of the two drug delivery channels, so as to realize the independent selection and switching of different formulation drugs and avoid cross-contamination between different drugs.

[0063] Specifically, the partition plate 62 divides the inner cavity of the medicine storage plate 61 into two independent medicine storage chambers, which are used to store different formulations of traditional Chinese medicine liquids. For example, the left chamber can store a warming and kidney-tonifying medicine liquid, and the right chamber can store a blood-activating and stasis-removing medicine liquid. According to the patient's condition, the first solenoid valve 66 or the second solenoid valve 67 can be opened and closed quickly to achieve switching, avoiding the cumbersome operation of frequently changing medicine liquids and cleaning when treating different patients, preventing the reduction of efficacy or adverse reactions caused by mixing of medicine liquids during treatment, improving treatment efficiency and the multi-scenario applicability of the device.

[0064] When it is necessary to deliver the Chinese medicine liquid on the right side, firstly open the first solenoid valve 66 and close the second solenoid valve 67. At this time, the first connecting pipe 63 is in the conducting state and the second connecting pipe 65 is in the cut-off state. Then, start the conveying component 64. The medicine liquid in the right medicine storage chamber flows along the first connecting pipe 63 under the negative pressure suction of the peristaltic pump. After being pressurized by the conveying component 64, it is evenly permeated into the medicine guide cotton 54 through the protective component 7, thus completing the directional delivery of the medicine liquid.

[0065] When it is necessary to deliver the Chinese medicine liquid on the left, the first solenoid valve 66 is closed and the second solenoid valve 67 is opened. At this time, the second connecting pipe 65 is in the conducting state and the first connecting pipe 63 is in the cut-off state. The medicine liquid in the left medicine storage chamber flows along the second connecting pipe 65 under the action of the conveying component 64, and also permeates into the medicine guide cotton 54 through the protective component 7, so as to realize the flexible switching of different formula medicine liquids.

[0066] like Figure 5 As shown, in one embodiment of this application, the protective component 7 includes a protective tube 71, a spring 72, a sealing block 73, and a guide post 74.

[0067] One end of the protective tube 71 is connected to the output end of the conveying component 64. The spring 72 is located inside the protective tube 71, and one end of the spring 72 is connected to the protective tube 71. The sealing block 73 is connected to the other end of the spring 72. The guide post 74 is located inside the protective tube 71, and one end of the guide post 74 is connected to the sealing block 73.

[0068] Specifically, when the Chinese medicine liquid enters the protective tube 71 under the action of the conveying component 64, the pressure of the liquid pushes the sealing block 73 to compress the spring 72. At this time, an annular gap is formed between the sealing block 73 and the inner wall of the protective tube 71, allowing the liquid to pass smoothly and flow into the drug-guiding cotton 54.

[0069] When the delivery component 64 stops working, the elastic restoring force of the spring 72 pushes the sealing block 73 to reset, so that it fits tightly against the inner wall of the protective tube 71, forming a reliable mechanical seal. This effectively prevents the backflow and leakage of the medicine, while also isolating it from the entry of outside air, avoiding oxidation and deterioration of the medicine in the cotton wool 54 and bacterial contamination, thus extending the effective usage time after a single application.

[0070] At the same time, when the patient wears or cleans the device housing 1, it prevents the patient's bodily fluids or liquids during device cleaning from entering the first connecting pipe 63, the second connecting pipe 65, and the delivery component 64, causing contamination.

[0071] The guide post 74 provides precise axial guidance for the reciprocating motion of the sealing block 73, preventing skew and jamming, and ensuring the sensitivity and reliability of the sealing action.

[0072] like Figure 6 and Figure 8 As shown, in one embodiment of this application, the processing mechanism 8 includes a heating plate 81, a second vibrating head 82, a signal receiver 83, a controller 84, and a stirring element 85.

[0073] There are two heating plates 81, which are symmetrically arranged on the bottom wall of the medicine storage plate 61 with respect to the length of the partition plate 62. There are two second vibrating heads 82, which are symmetrically arranged on the bottom wall of the medicine storage plate 61 with respect to the length of the partition plate 62. The signal receiver 83 is arranged on the fixed plate 3. The controller 84 is arranged on the fixed plate 3. The stirring component 85 is arranged on the bottom wall of the medicine storage plate 61.

[0074] It should be noted that the heating plate 81 described in this embodiment uses a PTC ceramic constant-temperature heating element, and its surface temperature is controlled within the range of 35℃ to 42℃. This temperature range is close to the human body surface temperature, which can effectively reduce the viscosity of the traditional Chinese medicine liquid and enhance the molecular thermal motion activity, without causing the decomposition of the effective components or protein denaturation due to excessive temperature. The two heating plates 81 are respectively attached to the bottom walls of the left and right medicine storage chambers, and uniformly preheat the medicine liquid through heat conduction, so that the temperature of the medicine liquid is stabilized at the optimal penetration temperature of 38℃±2℃. At this temperature, the surface tension of the medicine liquid is reduced by about 15%, the dynamic viscosity is reduced by 20% to 30%, and the ion migration rate driven by the subsequent electric field is significantly improved.

[0075] The second transducer 82 described in this embodiment is a miniature ultrasonic transducer with a working frequency set between 25kHz and 42kHz. It acts on the mixture of Chinese medicine powder and solvent through high-frequency ultrasonic vibration, and uses the ultrasonic cavitation effect to achieve non-contact micro-crushing of Chinese medicine particles, further refining the particle size of Chinese medicine powder to below 20μm. It does not require a mechanical grinding head, has a miniature structure, is wear-free and does not cause powder jamming, and is suitable for the narrow installation space of wearable devices.

[0076] In addition, it should be noted that the signal receiver 83 described in this embodiment is electrically connected to the heating plate 81, the second vibrating head 82 and the micro magnetic stirrer 851, and is used to receive external control commands and provide real-time feedback on the working status parameters of each component, including key data such as liquid temperature, ultrasonic power and vibration frequency.

[0077] The controller 84, as the core processing unit, has a built-in PID temperature control algorithm and an adaptive power adjustment module. It can dynamically adjust the output power of the heating plate 81 and the vibration parameters of the second vibrator 82 according to the real-time data transmitted by the signal receiver 83, so as to ensure that the liquid medicine is always in the preset optimal physical state. The controller 84 and the signal receiver 83 are common electronic control components on the market. Their specific models and circuit connection methods can be selected and configured according to the actual application scenario. The internal control program is a well-known technology, so it will not be described in detail here.

[0078] Specifically, when secondary processing of traditional Chinese medicine liquid is required, the heating plate 81 is first activated to preheat the liquid in the storage chamber. Under the control of the controller 84, the heating plate 81 slowly raises the liquid from room temperature to the optimal penetration temperature of the drug using a step-by-step heating strategy, avoiding local overheating that could damage the components of the liquid.

[0079] At the same time, the second vibrator 82 starts high-frequency ultrasonic vibration. The ultrasonic energy of the bottom wall of the medicine storage plate 61 is transmitted to the inside of the medicine liquid through the metal wall, causing the cavitation bubbles in the liquid to grow and collapse periodically. The local shock wave and micro-jet generated at the moment of bubble collapse carry out all-round mechanical crushing of the suspended Chinese medicine particles, further breaking down the larger medicinal tissue fragments into micron-sized particles, and significantly improving the dissolution rate and bioavailability of the effective ingredients.

[0080] like Figure 6 and Figure 8 As shown, in one embodiment of this application, the stirring element 85 includes a micro magnetic stirrer 851 and a stir bar 852.

[0081] Two micro magnetic stirrers 851 are provided, and the two micro magnetic stirrers 851 are symmetrically arranged on the bottom wall of the medicine storage plate 61 with the width of the partition plate 62 as the central axis. The stir bar 852 is symmetrically arranged on the medicine storage plate 61 with the width of the partition plate 62 as the central axis.

[0082] It should be noted that the micro magnetic stirrer 851 described in this embodiment drives the stir bar 852 to rotate at high speed through an alternating magnetic field. The rotation speed can be steplessly adjusted within the range of 100 to 800 rpm, thereby achieving continuous stirring of the medicine liquid in the storage chamber, preventing the precipitation and stratification of traditional Chinese medicine, and ensuring that the concentration of the medicine liquid is uniform.

[0083] Specifically, during the secondary processing of the traditional Chinese medicine extract, the controller 84 simultaneously activates the micro magnetic stirrer 851. The alternating magnetic field penetrates the metal bottom wall of the storage plate 61 and acts on the stir bar 852, driving it to rotate at high speed at the bottom of the storage chamber. As the stir bar 852 rotates, it creates strong turbulent vortices in the extract, effectively breaking the common solid-liquid phase separation phenomenon in traditional Chinese medicine extracts. This allows the precipitated residue at the bottom to be resuspended and evenly dispersed in the liquid phase.

[0084] like Figure 7 As shown, in one embodiment of this application, the seal 9 includes a sealing cap 91 and a sealing gasket 92.

[0085] The sealing cover 91 is threadedly connected to the outer casing 1 of the device; the sealing gasket 92 is disposed on the bottom wall of the sealing cover 91.

[0086] Specifically, when you want to inject the traditional Chinese medicine liquid into the storage chamber, first unscrew the sealing cap 91, remove the sealing gasket 92 for cleaning and disinfection, and then slowly pour the prepared traditional Chinese medicine liquid into the corresponding chamber along the inlet of the storage plate 61. After the medicine is added, tighten the sealing cap 91. The sealing cap 91 squeezes the sealing gasket 92 to make it elastically deform and tightly fill the gap between the sealing cap 91 and the inlet of the storage plate 61, forming a reliable static sealing interface to prevent leakage of the medicine liquid when the device is moved or tilted. At the same time, it blocks dust, microorganisms and other pollutants from the external environment from entering the storage chamber, ensuring the purity and stability of the traditional Chinese medicine liquid during storage.

[0087] like Figure 3 As shown, in one embodiment of this application, the limiting ring 42 and the guide cylinder 46 are cylindrical structures, and the outer wall of the limiting ring 42 slides in conjunction with the inner wall of the guide cylinder 46.

[0088] Specifically, the limiting ring 42 slides in the guide cylinder 46 to ensure that the first vibrator 44 can only float vertically and vertically, and cannot sway left and right or tilt and get stuck. This ensures that the electrode spacing is constant during electric field driving and avoids fluctuations in electric field strength and a decrease in penetration efficiency due to positional deviation.

[0089] In summary, the TCM herbal infiltration therapy device for kidney disease according to this application embodiment, through the setting of floating mechanism 4, multiple floating mechanisms 4 are arranged in a ring array. Each group is equipped with an ultrasonic conductive silicone pad 41, a first vibrating head 44, a guide cylinder 46 and a first spring 47. It can float slightly along the axis, conform to the physiological curve of the human waist, and adaptively adjust the contact pressure between each treatment point and the skin surface to ensure uniform electric field distribution and consistent penetration depth. It avoids gaps between the ultrasonic conductive silicone pad 41 and the skin, which would lead to ultrasonic energy attenuation and electric field distortion. It makes the ultrasonic conductive silicone pad 41, the second positive electrode 55 and the second negative electrode 56 closely adhere to the kidney acupoint area, realizing efficient transdermal penetration of Chinese medicine ions under the dual drive of ultrasonic cavitation effect and directional electric field.

[0090] In the description of this specification, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0091] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0092] Although embodiments of this application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting this application. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of this application.

Claims

1. A traditional Chinese medicine transdermal therapy device for kidney disease, characterized in that, include: The device consists of a housing (1), a fixed plate (3), and a floating mechanism (4), wherein, The fixing plate (3) is disposed on the inner wall of the outer casing (1) of the device; Multiple floating mechanisms (4) are provided, and the multiple floating mechanisms (4) are arranged in a ring array on the fixed plate (3); The floating mechanism (4) includes an ultrasonic conductive silicone pad (41), a limiting ring (42), a limiting groove (43), a first vibrating head (44), a guide ring (45), a guide cylinder (46), and a first spring (47), wherein, The ultrasonic conductive silicone pad (41) is disposed inside the fixing plate (3); The limiting ring (42) is disposed on the outer wall of the ultrasonic conductive silicone pad (41); The fixing plate (3) is provided with a limiting groove (43) that is compatible with the limiting ring (42); The first transducer (44) is disposed on the ultrasonic conductive silicone pad (41); The guide ring (45) is disposed on the outer wall of the first vibrating head (44); The guide cylinder (46) is mounted on the fixed plate (3); The first spring (47) is disposed inside the guide cylinder (46), and one end of the first spring (47) is connected to the guide ring (45), and the other end of the first spring (47) is connected to the guide cylinder (46).

2. The traditional Chinese medicine permeation therapy device for kidney disease according to claim 1, characterized in that, It also includes a fixing component (2), an electrode coupling assembly (5), a switching mechanism (6), a processing mechanism (8), and a sealing component (9), wherein, The fastener (2) is disposed on the outer wall of the housing (1) of the device; The electrode coupling assembly (5) is disposed on the bottom wall of the fixed plate (3); The switching mechanism (6) is disposed on the inner wall of the device housing (1); The processing mechanism (8) is disposed on the bottom wall of the switching mechanism (6); The seal (9) is disposed on the housing (1) of the device.

3. The traditional Chinese medicine permeation therapy device for kidney disease according to claim 2, characterized in that, The electrode coupling assembly (5) includes an insulating layer (51), a first positive electrode (52), a first negative electrode (53), a drug-conducting cotton (54), a second positive electrode (55), and a second negative electrode (56), wherein, The insulating isolation layer (51) is disposed on the bottom wall of the fixing plate (3); The first positive electrode (52) and the first negative electrode (53) are sequentially disposed in the corresponding slots of the insulating layer (51); The drug-conducting cotton (54) is disposed within the insulating layer (51); The second positive electrode (55) is disposed on the outer wall of the ultrasonic conductive silicone pad (41); The second negative electrode (56) is disposed inside the ultrasonic conductive silicone pad (41).

4. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 2, characterized in that, The fastener (2) includes a first connecting strap (21), a second connecting strap (22), and a third connecting strap (23), wherein, One end of the first connecting strip (21) is connected to the device housing (1), and the other end of the first connecting strip (21) is connected to another device housing (1); One end of the second connecting strip (22) is connected to the device housing (1), and one end of the third connecting strip (23) is connected to the other end of the second connecting strip (22); The other end of the third connecting strip (23) is connected to another of the device housings (1).

5. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 2, characterized in that, The switching mechanism (6) includes a medicine storage plate (61), a partition plate (62), a first connecting pipe (63), a conveying component (64), a second connecting pipe (65), a first solenoid valve (66), a second solenoid valve (67), and a protective component (7), wherein, The medicine storage plate (61) is disposed on the inner wall of the outer shell (1) of the device; The partition plate (62) is disposed on the medicine storage plate (61); One end of the first connecting pipe (63) is connected to the medicine storage plate (61), and the input end of the conveying component (64) is connected to the other end of the first connecting pipe (63); One end of the second connecting pipe (65) is connected to the medicine storage plate (61), and the other end of the second connecting pipe (65) is connected to the input end of the conveying component (64); One end of the protective component (7) is connected to the output end of the conveying component (64).

6. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 5, characterized in that, The protective component (7) includes a protective tube (71), a second spring (72), a sealing block (73), and a guide post (74), wherein, One end of the protective tube (71) is connected to the output end of the conveying component (64); The second spring (72) is disposed inside the protective tube (71), and one end of the second spring (72) is connected to the protective tube (71), and the sealing block (73) is connected to the other end of the second spring (72); The guide post (74) is disposed inside the protective tube (71), and one end of the guide post (74) is connected to the sealing block (73).

7. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 5, characterized in that, The processing mechanism (8) includes a heating plate (81), a second vibrating head (82), a signal receiver (83), a controller (84), and a stirring component (85), wherein, Two heating plates (81) are provided, and the two heating plates (81) are symmetrically arranged on the bottom wall of the medicine storage plate (61) with respect to the length center axis of the partition plate (62); There are two second vibrating heads (82), and the two second vibrating heads (82) are symmetrically arranged on the bottom wall of the medicine storage plate (61) about the length center axis of the partition plate (62); The signal receiver (83) is mounted on the fixed plate (3); The controller (84) is mounted on the fixed plate (3); The stirring component (85) is disposed on the bottom wall of the medicine storage plate (61).

8. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 7, characterized in that, The stirring component (85) includes a micro magnetic stirrer (851) and a stir bar (852), wherein, Two micro magnetic stirrers (851) are provided, and the two micro magnetic stirrers (851) are symmetrically arranged on the bottom wall of the medicine storage plate (61) with respect to the width of the partition plate (62). The stir bar (852) is symmetrically arranged on the medicine storage plate (61) with respect to the width of the partition plate (62).

9. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 2, characterized in that, The sealing element (9) includes a sealing cap (91) and a sealing gasket (92), wherein, The sealing cap (91) is threadedly connected to the outer casing (1) of the device; The sealing gasket (92) is disposed on the bottom wall of the sealing cover (91).

10. A traditional Chinese medicine permeation therapy device for kidney disease according to claim 1, characterized in that, The limiting ring (42) and the guide cylinder (46) are cylindrical structures, and the outer wall of the limiting ring (42) slides in conjunction with the inner wall of the guide cylinder (46).

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