Acetylhydrazine derivatives having phenyl heteroatom substituents, processes for their preparation and use

By synthesizing acetylhydrazine derivatives with phenyl heteroatom substituents, a broad-spectrum antifungal fungicide was generated, solving the problems of poor control efficacy and drug resistance of existing fungicides against various plant pathogenic fungi, and achieving efficient control of various fungi.

CN122277439APending Publication Date: 2026-06-26HEFEI ZHINONG KECHUANG AGRICULTURAL TECHNOLOGY CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HEFEI ZHINONG KECHUANG AGRICULTURAL TECHNOLOGY CO LTD
Filing Date
2026-04-02
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing fungicides are not effective in controlling a variety of plant pathogenic fungi, especially against Fusarium graminearum and various resistant strains of wheat, and they also have the problem of drug resistance, making it difficult to meet the needs of comprehensive prevention and control.

Method used

Acetylhydrazine derivatives with phenyl heteroatom substituents were synthesized by reacting them in the presence of a condensing agent and an organic base to generate acetylhydrazine derivatives with broad-spectrum antifungal activity, which can be used to prepare plant fungicides.

Benefits of technology

It exhibits excellent broad-spectrum antifungal effects against fungi such as Fusarium graminearum, Sclerotinia sclerotiorum, Botrytis cinerea, Rhizoctonia solani, Alternaria alternata, Curvularia crescentis, Phytophthora capsici, and Sclerotium sclerotiorum, and also shows highly sensitive antifungal activity against drug-resistant strains such as resistant Fusarium graminearum.

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Abstract

This invention discloses a class of acetylhydrazine derivatives with phenyl heteroatom substituents, their preparation methods, and applications; the acetylhydrazine derivatives have the general structural formula shown below, and exhibit excellent broad-spectrum antifungal effects against fungi including *Fusarium graminearum*, *Sclerotinia sclerotiorum*, *Botrytis cinerea*, *Rhizoctonia solani*, *Alternaria alternata*, *Curvularia lunata*, *Phytophthora capsici*, *Sclerotium sclerotiorum*, and *Fusarium graminearum*.
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