A zinc chelating peptide from euphausia superba and a preparation method and application thereof

By preparing zinc chelate peptides derived from Antarctic krill, the problems of poor taste and low bioavailability of existing zinc supplements have been solved, achieving efficient and safe zinc supplementation and improving resource utilization and industrial value.

CN122277663APending Publication Date: 2026-06-26YELLOW SEA FISHERIES RES INST CHINESE ACAD OF FISHERIES SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
YELLOW SEA FISHERIES RES INST CHINESE ACAD OF FISHERIES SCI
Filing Date
2026-04-14
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing zinc supplements suffer from poor taste, strong gastrointestinal irritation, low bioavailability, and significant side effects, making it difficult to effectively improve the problem of insufficient dietary zinc intake for approximately 2 billion people worldwide in the short term.

Method used

Using Antarctic krill powder as raw material, peptides with zinc chelating ability are prepared through enzymatic hydrolysis, desalination, and ultrafiltration. These peptides include KEDGF, QQLVDDHF, LVWVNEEDQLR, and YGYIHSCPTNLGTGMR, which serve as carriers for fourth-generation zinc supplements.

Benefits of technology

It improves zinc chelation capacity, significantly enhances zinc absorption, provides a safe and efficient way to supplement zinc, and improves resource utilization and industrial value.

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Abstract

This invention provides an Antarctic krill-derived zinc chelating peptide, its preparation method, and its applications, belonging to the field of marine bioactive peptide technology. This invention utilizes defatted Antarctic krill powder to prepare high-affinity zinc chelating peptides, and the obtained peptides exhibit excellent zinc chelating capabilities. Mass spectrometry identification identified four peptides, all of which possess excellent zinc chelating abilities. The Antarctic krill-derived zinc chelating peptide prepared by this invention significantly enhances the zinc chelating ability compared to currently confirmed Antarctic krill peptides, and can be used as a carrier for fourth-generation zinc supplements in the prevention and treatment of zinc deficiency in common foods, health foods, and pharmaceuticals. This invention achieves high-value and precise utilization of defatted Antarctic krill powder, a processing byproduct, effectively improving resource utilization and industrial value, while also providing a new feasible approach for the development of safe and efficient zinc supplements.
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