A multi-stage separation and purification equipment for collagen peptides

Abstract

This invention discloses a multi-stage separation and purification device for collagen peptides, relating to the field of collagen processing technology. It aims to solve the technical problem of difficulty in separating and purifying collagenase raw materials due to their diversity, as demonstrated by existing equipment. The device includes an enzymatic hydrolysis tank with a multi-stage separation mechanism at its bottom. This mechanism comprises a drive rod assembly, a fixed cylinder assembly, and a centrifugal inner ball assembly. The drive rod assembly drives the centrifugal inner ball assembly to rotate within the fixed cylinder assembly. The centrifugal inner ball assembly expands radially due to centrifugal force, forming a variable-gap extrusion and grinding chamber with the inner wall of the fixed cylinder assembly. It has two working states: bone fragment crushing and fiber chopping. The centrifugal ball segments have grooves, within which arc blades are movably inserted. These arc blades automatically extend and retract according to the rotational speed under the control of an elastic telescopic rod. A linked defoaming mechanism includes a guide plate and a defoaming disc, using rotational power to guide the foam to the vortex blades for rupture. This invention can simultaneously achieve bone fragment crushing, fiber depolymerization, and multi-stage filtration and defoaming, significantly improving raw material utilization and purification efficiency.

Description

Technical Field

[0001] This invention relates to the field of collagen processing technology, and more specifically, to a multi-stage separation and purification device for collagen peptides. Background Technology

[0002] Collagen peptides are widely used in functional foods, biomedicine, cosmetics and other fields due to their good biocompatibility and easy absorption. Market demand continues to grow, and enzymatic hydrolysis is currently the mainstream industrial process for preparing collagen peptides.

[0003] In actual production, bone-derived collagen peptides, such as bovine bones, pig bones, and fish bones, are used as raw materials. During the enzymatic hydrolysis process, a large amount of bone debris and lumpy undecomposed tissue often remain in the raw materials, resulting in insufficient contact between the enzyme preparation and the raw materials, low conversion and utilization rates of the raw materials, and large particulate impurities can easily cause blockages in subsequent separation processes, increasing equipment maintenance costs.

[0004] When collagen peptides are prepared from raw materials rich in connective tissue, such as pigskin, cowhide, and animal tendons, the enzymatic hydrolysis process produces a large number of incompletely degraded short collagen fibers. These fibers are prone to entanglement and sticking together, which not only encapsulates the raw materials and enzyme preparations, further aggravating the problem of insufficient enzymatic hydrolysis, but also clogs the separation screen, increases the difficulty of material discharge, and seriously affects the continuous and stable operation of the production line.

[0005] Current collagen peptide separation and purification equipment mostly uses a single sieving structure, which cannot simultaneously achieve the crushing and refining of blocky impurities, the disintegration and deagglomeration of fiber clusters, and multi-stage separation and purification. This makes it difficult to balance raw material utilization and purification efficiency, and it cannot meet the processing requirements of collagen enzymatic hydrolysates containing complex impurities, exhibiting significant technical shortcomings. Therefore, we propose a multi-stage separation and purification device for collagen peptides. Summary of the Invention

[0006] The purpose of this invention is to provide a multi-stage separation and purification device for collagen peptides, so as to solve the technical problem that the diversity of collagenase raw materials makes it difficult for existing equipment to separate and purify them.

[0007] To solve the above technical problems, the present invention provides the following technical solution: a multi-stage separation and purification device for collagen peptides, including an enzymatic hydrolysis tank, wherein a multi-stage separation mechanism is provided at the bottom of the enzymatic hydrolysis tank, and a linkage defoaming mechanism is provided on the inner wall of the enzymatic hydrolysis tank at the top of the multi-stage separation mechanism, wherein the bottom of the linkage defoaming mechanism is fixedly connected to the multi-stage separation mechanism; The multi-stage separation mechanism includes a drive rod assembly, a fixed cylinder assembly, and a centrifugal inner ball assembly. The drive rod assembly is rotatably inserted into the bottom of the enzymatic hydrolysis tank, the fixed cylinder assembly is fixedly disposed on the inner wall of the enzymatic hydrolysis tank, and the centrifugal inner ball assembly is sleeved on the drive rod assembly near the inside of the fixed cylinder assembly. The drive rod assembly drives the centrifugal inner ball assembly to rotate synchronously within the fixed cylinder assembly. The centrifugal inner ball assembly can radially open with the centrifugal force generated by the rotation. After opening, the centrifugal inner ball assembly and the inner wall of the fixed cylinder assembly enclose a variable gap extrusion and grinding chamber, which is used to crush and refine large bone fragments and undecomposed materials in the collagen peptide hydrolysate. The centrifugal inner ball assembly, by adjusting the fitting gap with the inner wall of the fixed cylinder assembly, has at least two working states: one is the bone fragment crushing state, in which the gap is narrowed, used for high-intensity extrusion grinding and crushing of hard bone fragments and blocky materials; the other is the fiber chopping state, in which the gap is adapted and adjusted, used for chopping, depolymerizing and dispersing tangled collagen fibers.

[0008] Preferably, the enzymatic hydrolysis tank has an inlet at the top, a base at the bottom, a discharge port on the outer side of the bottom, and a separatory plate at the top inside.

[0009] Preferably, the multi-stage separation mechanism further includes a liquid guide tube, which is fixedly sleeved on the drive rod assembly.

[0010] Preferably, the drive rod assembly includes a main gear disc and a main shaft. The main shaft is rotatably inserted into the bottom end of the enzymatic hydrolysis tank, and the main gear disc is fixedly sleeved on the bottom end of the main shaft. The main gear disc is driven by an external power mechanism.

[0011] Preferably, the fixed cylinder assembly includes a bottom cylinder, an inner support rod, an outer straight cylinder, an outer hemispherical cylinder, and a bushing. The bottom cylinder is fixedly disposed on the inner wall of the enzymatic hydrolysis tank. The bushing is rotatably sleeved on the drive rod assembly. The inner support rod is arranged in a ring at equal intervals on the inner wall of the bottom cylinder. The end of the inner support rod away from the bottom cylinder is connected to the bushing. The outer straight cylinder is fixedly disposed on the top of the bottom cylinder, and the outer hemispherical cylinder is fixedly disposed on the outer straight cylinder.

[0012] Preferably, the centrifugal inner ball assembly includes a fixed sleeve, a movable sleeve, a spring, a connecting rod unit, and centrifugal ball petals. The fixed sleeve is fixedly sleeved on the drive rod assembly, and the movable sleeve is movably sleeved on the drive rod assembly. One end of the spring is fixedly connected to the fixed sleeve, and the other end of the spring is fixedly connected to the movable sleeve. One end of the connecting rod unit is hinged to the fixed sleeve, and the other end of the connecting rod unit is hinged to the movable sleeve. The centrifugal ball petals are fixedly connected to the connecting rod unit.

[0013] Preferably, the linkage unit includes a main linkage and a secondary linkage. One end of the main linkage is hinged to the fixed bearing sleeve, and the other end of the main linkage is fixedly connected to the centrifugal ball petal. One end of the secondary linkage is hinged to the movable bearing sleeve, and the other end of the secondary linkage is hinged to the main linkage.

[0014] Preferably, the centrifugal ball petal has fan-shaped, equally spaced slots, and an arc blade is movably inserted into the slot. An arc plate is fixedly mounted on the centrifugal ball petal, and a plurality of elastic telescopic rods are fixedly mounted on the arc plate. The end of the elastic telescopic rod away from the arc plate is fixedly connected to the arc blade.

[0015] Preferably, the linkage defoaming mechanism includes a flow guide plate and a defoaming plate. The flow guide plate is fixedly sleeved on the top of the drive rod assembly, and the defoaming plate is fixedly disposed on the inner wall of the enzymatic hydrolysis tank at the position of the flow guide plate.

[0016] Preferably, the guide plate is provided with liquid inlet grooves in a ring at equal intervals, and the guide plate is also provided with oblique flow holes in a ring at equal intervals; The defoaming disc is arc-shaped and inwardly folded, and the inner wall of the defoaming disc is fixed with swirling blades at equal intervals in a ring.

[0017] Compared with the prior art, the beneficial effects of the present invention are: 1. This invention utilizes a centrifugal inner ball assembly. When the drive rod assembly rotates the assembly, the centrifugal ball petals open radially under centrifugal force, forming a variable-gap extrusion and grinding chamber with the inner wall of the fixed cylinder assembly. The rotation speed can be adjusted to flexibly switch between bone fragment crushing and fiber chopping states. In the bone fragment crushing state, the gap narrows, allowing for high-intensity extrusion and grinding of hard bone fragments and lumpy materials. In the fiber chopping state, the gap is adjusted to effectively chop, deagglomerate, and disperse tangled collagen fibers. This structure enables targeted treatment of different types of impurities using the same equipment, solving the technical problem that traditional equipment cannot simultaneously crush and refine lumpy impurities and break up and deagglomerate fiber clumps, significantly improving the utilization rate of raw material enzymatic hydrolysis and the efficiency of separation and purification.

[0018] 2. This invention features fan-shaped, evenly spaced slots on a centrifugal disc, within which movably inserted arc blades are connected to an arc plate via elastic telescopic rods. During low-speed bone fragment crushing, the centrifugal force is relatively small, and the arc blades retract into the slots under the tension of the elastic telescopic rods, preventing blade breakage and focusing on compression and grinding. During high-speed fiber chopping, the centrifugal force increases, causing the arc blades to be thrown out of the slots and protrude from the disc surface, enabling high-speed chopping of tangled collagen fibers. This design achieves intelligent switching of the arc blades' automatic extension and retraction according to the rotational speed, requiring no additional power or external control. This extends the blade's lifespan and significantly improves the processing capacity of enzymatic hydrolysates containing fiber clumps.

[0019] 3. This invention features a linked defoaming mechanism, including a guide plate fixedly mounted on the top of the drive rod assembly and a defoaming disc fixed to the inner wall of the enzymatic hydrolysis tank. The guide plate has oblique flow holes, and the defoaming disc is arc-shaped with inwardly folded edges and swirling blades evenly spaced on its inner wall. During operation, the guide plate rotates synchronously with the drive rod assembly, guiding the foam from the upper part of the enzymatic hydrolysis tank through the oblique flow holes to the edge and throwing it towards the defoaming disc. The arc-shaped inwardly folded structure causes the foam to accumulate, and it bursts instantly upon high-speed impact with the swirling blades. This mechanism utilizes the rotational power of the multi-stage separation mechanism itself to achieve efficient defoaming without additional energy consumption, simplifying the equipment structure, avoiding interference from foam accumulation on discharge and separation purification, and ensuring continuous and stable production operation. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall external structure of the present invention; Figure 2 This is a schematic diagram of the enzymatic hydrolysis vessel structure of the present invention; Figure 3 This is a cross-sectional schematic diagram of the internal structure of the enzymatic hydrolysis vessel of the present invention; Figure 4 This is a schematic diagram of the multi-stage separation mechanism and the linked defoaming mechanism of the present invention; Figure 5 This is a cross-sectional view of the drive rod assembly, the fixed cylinder assembly, the centrifugal inner ball assembly, and the liquid guiding cylinder of the present invention. Figure 6 This is a cross-sectional view of the outer hemisphere, the centrifugal inner sphere assembly, and the liquid guiding cylinder of the present invention. Figure 7 A schematic diagram of one set of connecting rod units and centrifugal spherical petals arranged in a ring with equal spacing in this invention; Figure 8 This is a schematic diagram of the disassembled structure of the centrifugal ball, the arc blade, and the elastic telescopic rod of the present invention; Figure 9 This is a schematic diagram of the assembly structure of the centrifugal ball, the arc blade, and the elastic telescopic rod of the present invention; Figure 10 This is a schematic diagram of the liquid inlet guide inside the enzymatic hydrolysis tank of the present invention; Figure 11 This is a schematic diagram of the cross-sectional structure of the drainage plate of the present invention; Figure 12 This is a cross-sectional view of the defoaming disc structure of the present invention.

[0021] Explanation of the labels in the diagram: 1. Enzymatic hydrolysis tank; 2. Inlet; 3. Base; 4. Outlet; 5. Separating tray; 6. Multi-stage separation mechanism; 7. Linked defoaming mechanism; 61. Drive rod assembly; 62. Fixed cylinder assembly; 63. Centrifugal inner ball assembly; 64. Liquid guide cylinder; 611. Main gear plate; 612. Main shaft; 621. Bottom cylinder; 622. Inner support rod; 623. Outer straight cylinder; 624. Outer hemispherical cylinder; 625. Bushing; 631. Fixed bearing sleeve; 632. Movable bearing sleeve; 633. Spring; 634. Linkage unit; 635. Centrifugal ball valve; 6341, Main connecting rod; 6342, Secondary connecting rod; 6351. Groove; 6352. Arc cutter; 6353. Arc plate; 6354. Flexible telescopic rod; 71. Drain plate; 72. Bubble extinguishing plate; 711. Liquid inlet tank; 712. Inclined flow hole; 721. Swirl blade. Detailed Implementation

[0022] like Figures 1 to 12 As shown, the present invention relates to a multi-stage separation and purification device for collagen peptides, including an enzymatic hydrolysis tank 1, a multi-stage separation mechanism 6 is provided at the bottom of the enzymatic hydrolysis tank 1, and a linkage defoaming mechanism 7 is provided on the inner wall of the enzymatic hydrolysis tank 1 at the top of the multi-stage separation mechanism 6, with the bottom of the linkage defoaming mechanism 7 fixedly connected to the multi-stage separation mechanism 6. The multi-stage separation mechanism 6 includes a drive rod assembly 61, a fixed cylinder assembly 62, and a centrifugal inner ball assembly 63. The drive rod assembly 61 is rotatably inserted into the bottom of the enzymatic hydrolysis tank 1, the fixed cylinder assembly 62 is fixedly installed on the inner wall of the enzymatic hydrolysis tank 1, and the centrifugal inner ball assembly 63 is sleeved on the drive rod assembly 61 near the inside of the fixed cylinder assembly 62. The drive rod assembly 61 drives the centrifugal inner ball assembly 63 to rotate synchronously within the fixed cylinder assembly 62. The centrifugal inner ball assembly 63 can radially open with the centrifugal force generated by the rotation. After opening, the centrifugal inner ball assembly 63 and the inner wall of the fixed cylinder assembly 62 enclose a variable gap extrusion and grinding chamber, which is used to crush and refine large bone fragments and undecomposed materials in the collagen peptide hydrolysate. The centrifugal inner ball assembly 63 has at least two working states by adjusting the fit gap with the inner wall of the fixed cylinder assembly 62: one is the bone fragment crushing state, in which the gap is narrowed and used for high-intensity extrusion grinding and crushing of hard bone fragments and blocky materials; the other is the fiber chopping state, in which the gap is adapted and adjusted and used for chopping, depolymerizing and dispersing tangled collagen fibers.

[0023] In this invention, the drive rod assembly 61 rotates at the bottom of the enzymatic hydrolysis tank 1 and drives the centrifugal inner ball assembly 63 to rotate synchronously inside the fixed cylinder assembly 62. Under the centrifugal force generated by the rotation, the centrifugal inner ball assembly 63 expands radially, forming a variable-gap extrusion and grinding chamber with the inner wall of the fixed cylinder assembly 62. After the collagen peptide enzymatic hydrolysate enters the enzymatic hydrolysis tank 1, it flows through the extrusion and grinding chamber to complete the impurity treatment. The centrifugal inner ball assembly 63 can switch between the bone fragment crushing state and the fiber chopping state by adjusting the fit gap with the inner wall of the fixed cylinder assembly 62. In the bone fragment crushing state, the gap narrows, which can perform high-intensity extrusion and grinding crushing of large pieces of bone fragments and undecomposed fragments in the enzymatic hydrolysate. In the fiber chopping state, the gap is adjusted to effectively chop, deagglomerate and disperse tangled collagen fibers. At the same time, the defoaming mechanism 7 is fixedly connected to the multi-stage separation mechanism 6. The top part moves synchronously with the multi-stage separation mechanism 6 to complete the multi-stage separation and purification of the enzymatic hydrolysate. This equipment relies on the centrifugal opening and closing characteristics of the centrifugal inner ball group 63 to form a variable gap extrusion grinding chamber, which realizes the targeted treatment of different types of impurities such as bone residue and collagen fiber clusters. It solves the technical problem that traditional equipment cannot simultaneously complete the crushing and refining of blocky impurities and the dispersing and deagglomeration of fiber clusters. Moreover, the two working states can flexibly adapt to the enzymatic hydrolysate treatment needs of different raw materials, effectively improving the enzymatic utilization rate of raw materials and the separation and purification efficiency of collagen peptides. At the same time, the fixed connection design of the defoaming mechanism 7 and the multi-stage separation mechanism 6 allows the equipment to realize the crushing, separation and defoaming operations simultaneously with only one drive, simplifying the overall transmission structure of the equipment and ensuring the continuity and stability of the multi-stage separation and purification of collagen peptides.

[0024] In an embodiment of the present invention, the enzymatic hydrolysis tank 1 has a feed inlet 2 at its top, a base 3 at its bottom, a discharge port 4 on the outer side of its bottom, and a liquid separator 5 at its top interior. The multi-stage separation mechanism 6 also includes a liquid guide cylinder 64, which is fixedly sleeved on the drive rod assembly 61.

[0025] In this invention, the stock solution to be enzymatically hydrolyzed is fed into the inlet 2 at the top of the enzymatic hydrolysis tank 1. After being uniformly guided by the liquid distribution plate 5 at the top of the enzymatic hydrolysis tank 1, it enters the tank. The base 3 at the bottom of the enzymatic hydrolysis tank 1 provides stable support for the entire device. The drive rod assembly 61 rotates at the bottom of the enzymatic hydrolysis tank 1 and drives the centrifugal inner ball assembly 63 to rotate synchronously inside the fixed cylinder assembly 62. The liquid guide cylinder 64, which is fixedly sleeved on the drive rod assembly 61, rotates synchronously with the drive rod assembly 61 to guide the enzymatic hydrolysate in the tank in a directional manner, so that the enzymatic hydrolysate fully enters the variable gap extrusion grinding chamber formed by the centrifugal inner ball assembly 63 and the inner wall of the fixed cylinder assembly 62.

[0026] In another embodiment of the present invention, the drive rod assembly 61 includes a main gear plate 611 and a main shaft 612. The main shaft 612 is rotatably inserted into the bottom end of the enzymatic hydrolysis tank 1, and the main gear plate 611 is fixedly sleeved on the bottom end of the main shaft 612. The main gear plate 611 is driven by an external power mechanism.

[0027] In this invention, the external power mechanism is an electric motor. The external motor outputs power as the power mechanism. The gear sleeved on the output end of the motor meshes with the main gear disk 611. Through gear meshing transmission, the main gear disk 611 is driven to rotate, which in turn drives the main shaft rod 612 fixedly sleeved on the main gear disk 611 to rotate synchronously at the bottom of the enzymatic hydrolysis tank 1. The drive rod group 61 composed of the main gear disk 611 and the main shaft rod 612 completes the stable transmission of power.

[0028] In another embodiment of the present invention, the fixed cylinder assembly 62 includes a bottom cylinder 621, an inner support rod 622, an outer straight cylinder 623, an outer hemispherical cylinder 624, and a bushing 625. The bottom cylinder 621 is fixedly disposed on the inner wall of the enzymatic hydrolysis tank 1. The bushing 625 is rotatably sleeved on the drive rod assembly 61. The inner support rod 622 is arranged in a ring at equal intervals on the inner wall of the bottom cylinder 621. The end of the inner support rod 622 away from the bottom cylinder 621 is connected to the bushing 625. The outer straight cylinder 623 is fixedly disposed on the top of the bottom cylinder 621, and the outer hemispherical cylinder 624 is fixedly disposed on the outer straight cylinder 623.

[0029] In this invention, the outer hemispherical cylinder 624 and the outer straight cylinder 623 are fixedly connected from top to bottom, together forming an inner wall of a combination of a straight cylinder and a hemispherical cylinder. This combined inner wall dynamically cooperates with the outer surface of the rotating centrifugal inner ball assembly 63 to form a variable-gap extrusion and grinding cavity.

[0030] The upper outer straight cylinder 623 has precision filter holes on its wall, forming a two-stage fine filtration zone; the lower outer hemispherical cylinder 624 has larger pores or slits on its hemispherical wall, forming a first-stage coarse filtration zone. During operation, the material in the enzymatic hydrolysate is thrown towards the inner wall of this combined system under centrifugal force. The outer hemispherical cylinder 624 area first intercepts larger particles of raw material residue, such as crushed bone fragments and dispersed fiber clumps, achieving first-stage coarse filtration. Subsequently, the finer slurry enters the outer straight cylinder 623 area under pressure, achieving second-stage fine filtration through its smaller filter holes. The clarified liquid after these two stages of filtration enters the cavity of the enzymatic hydrolysis tank 1 through the filter holes and is finally discharged through the discharge port 4. This design integrates dynamic extrusion grinding with multi-stage solid-liquid separation functions into one unit. The outer hemispherical cylinder 624 not only serves as the inner wall of the grinding chamber, participating in the crushing of blocky and fibrous impurities, but also acts as a primary coarse filter, intercepting most of the solid residue. The outer straight cylinder 623, while undertaking part of the grinding function, further completes the fine filtration of the slurry. This structure enables continuous operation of crushing, coarse filtration, and fine filtration, greatly simplifying the process flow and equipment structure, avoiding losses and contamination caused by material transfer between multiple devices, and significantly improving the separation and purification efficiency and product yield of collagen peptides.

[0031] In an embodiment of the present invention, the centrifugal inner ball assembly 63 includes a fixed sleeve 631, a movable sleeve 632, a spring 633, a connecting rod unit 634, and a centrifugal ball petal 635. The fixed sleeve 631 is fixedly sleeved on the drive rod assembly 61, and the movable sleeve 632 is movably sleeved on the drive rod assembly 61. One end of the spring 633 is fixedly connected to the fixed sleeve 631, and the other end of the spring 633 is fixedly connected to the movable sleeve 632. One end of the connecting rod unit 634 is hinged to the fixed sleeve 631, and the other end of the connecting rod unit 634 is hinged to the movable sleeve 632. The centrifugal ball petal 635 is fixedly connected to the connecting rod unit 634.

[0032] In this invention, the fixed sleeve 631 is fixedly sleeved on the drive rod assembly 61 and rotates synchronously with the drive rod assembly 61; the movable sleeve 632 is movably sleeved on the drive rod assembly 61 and can slide axially; one end of the spring 633 is fixedly connected to the fixed sleeve 631 and the other end is fixedly connected to the movable sleeve 632, providing a restoring elastic force for the movable sleeve 632; one end of the connecting rod unit 634 is hinged to the fixed sleeve 631 and the other end is hinged to the movable sleeve 632; and the centrifugal ball petal 635 is fixedly connected to the connecting rod unit 634.

[0033] During operation, the drive rod assembly 61 drives the fixed bearing sleeve 631 to rotate, and the centrifugal ball petal 635 rotates together with the connecting rod unit 634. Under the action of centrifugal force, the centrifugal ball petal 635 drives the connecting rod unit 634 to open outward radially. At this time, the movable bearing sleeve 632 overcomes the elastic force of the spring 633 and slides along the drive rod assembly 61 towards the fixed bearing sleeve 631, causing the centrifugal ball petal 635 to expand outward and form a variable gap extrusion grinding chamber with the inner wall of the fixed cylinder assembly 62. When the speed decreases or stops, the spring 633 pushes the movable bearing sleeve 632 to reset, and the connecting rod unit 634 drives the centrifugal ball petal 635 to retract inward, thereby changing the size of the gap of the extrusion grinding chamber.

[0034] In an embodiment of the present invention, the linkage unit 634 includes a main linkage 6341 and a secondary linkage 6342. One end of the main linkage 6341 is hinged to the fixed bearing sleeve 631, and the other end of the main linkage 6341 is fixedly connected to the centrifugal ball petal 635. One end of the secondary linkage 6342 is hinged to the movable bearing sleeve 632, and the other end of the secondary linkage 6342 is hinged to the main linkage 6341.

[0035] In this invention, the drive rod assembly 61 drives the fixed bearing sleeve 631 to rotate. Centrifugal force causes the centrifugal ball petal 635 to open radially outward. The centrifugal ball petal 635 transmits its motion to the auxiliary link 6342 through the main link 6341. The auxiliary link 6342 then pulls the movable bearing sleeve 632 to overcome the elastic force of the spring 633 and slide along the drive rod assembly 61 toward the fixed bearing sleeve 631. Since the main link 6341 and the auxiliary link 6342, as well as the two links and the fixed bearing sleeve 631 and the movable bearing sleeve 632, are all hinged, a variable link triangle structure is formed. This makes the radial displacement of the centrifugal ball petal 635 and the axial sliding of the movable bearing sleeve 632 have a stable proportional relationship. When the rotation speed changes, the opening amount of the centrifugal ball petal 635 is continuously adjustable. At the same time, the main link 6341 and the auxiliary link 6342 jointly constrain the motion trajectory of the centrifugal ball petal 635, ensuring that it always maintains concentricity with the inner wall of the fixed cylinder assembly 62 during rotation.

[0036] In another embodiment of the present invention, the centrifugal ball petal 635 is provided with fan-shaped slots 6351 at equal intervals, and the slots 6351 are movably inserted with arc blades 6352. The centrifugal ball petal 635 is fixedly provided with an arc plate 6353, and a plurality of elastic telescopic rods 6354 are fixedly provided on the arc plate 6353. The end of the elastic telescopic rod 6354 away from the arc plate 6353 is fixedly connected to the arc blades 6352.

[0037] In this invention, the moving rod assembly 61 drives the centrifugal inner ball assembly 63 to rotate, and the centrifugal ball petals 635 open radially with the connecting rod unit 634, forming a compression and grinding chamber with the inner wall of the fixed cylinder assembly 62. At the same time, the arc blade 6352 can slide outward along the slot 6351 under the action of centrifugal force, and the elastic telescopic rod 6354 is stretched and provides a reset pulling force. In the bone debris crushing state, the equipment operates at a lower speed, the centrifugal force is smaller, the gap of the compression and grinding chamber is relatively large, and the centrifugal ball petals 635 open to a smaller extent. At this time, the centrifugal force on the arc blade 6352 is insufficient to overcome the pulling force of the elastic telescopic rod 6354. Most of the arc blade 6352 retracts into the slot 6351, and only the outer surface of the centrifugal ball petals 635 cooperates with the inner wall of the fixed cylinder assembly 62 to perform high-intensity compression, grinding, and crushing of hard bone debris and blocky materials, avoiding premature extension of the arc blade 6352 which would cause blade edge damage or ineffective cutting.

[0038] In the fiber cutting state, the equipment is increased to a higher speed, the centrifugal force is significantly increased, the arc blade 6352 is thrown out of the groove 6351 and protrudes from the surface of the centrifugal ball petal 635. At the same time, due to the increase in speed, the radial opening of the centrifugal ball group 63 increases, the gap of the extrusion and grinding chamber is adapted to narrow, and the protruding arc blade 6352 performs high-speed cutting, depolymerization and dispersion of the entangled collagen fibers.

[0039] Through the cooperation of the slot 6351, the arc blade 6352, the arc plate 6353, and the elastic telescopic rod 6354, the extension and retraction of the arc blade 6352 are controlled by the balance of centrifugal force and elastic restoring force, automatically matching different working states of the equipment. When crushing bone residue at low speed, the arc blade 6352 retracts to protect the blade and focus on extrusion and grinding; when chopping fibers at high speed, the arc blade 6352 actively extends, realizing the superposition of cutting and chopping functions. The intelligent switching between the two processing modes can be completed without additional power or external control, which significantly improves the processing capacity of the multi-stage separation mechanism 6 for enzymatic hydrolysate containing fiber clusters, while avoiding blade wear caused by excessive cutting of hard bone residue and extending the service life of the equipment.

[0040] In another embodiment of the present invention, the linkage defoaming mechanism 7 includes a flow guide plate 71 and a defoaming plate 72. The flow guide plate 71 is fixedly sleeved on the top of the drive rod assembly 61, and the defoaming plate 72 is fixedly disposed on the inner wall of the enzymatic hydrolysis tank 1 at the position of the flow guide plate 71.

[0041] In this invention, the drive rod assembly 61 drives the multi-stage separation mechanism 6 to rotate to process bone residue and fibrous impurities in the enzymatic hydrolysate. At the same time, the guide plate 71, which is fixedly sleeved on the top of the drive rod assembly 61, rotates at high speed, pushing the foam and gas-liquid mixture generated in the upper part of the enzymatic hydrolysis tank 1 in a directional manner toward the defoaming plate 72. Under the push of the guide plate 71, the foam hits the stationary defoaming plate 72, and under the mechanical impact and shearing action, the bubbles burst, and the liquid phase falls back into the enzymatic hydrolysis tank 1 to continue to participate in the separation and purification.

[0042] By cooperating with the flow guide plate 71 and the defoaming plate 72, efficient defoaming can be achieved using the rotational power of the multi-stage separation mechanism 6 itself, simplifying the overall structure of the equipment and reducing energy consumption and manufacturing costs. The flow guide plate 71 is fixed to the top of the drive rod assembly 61 and is located in the foam enrichment area above the enzymatic hydrolysis tank 1. It can promptly push the foam to the defoaming plate 72 for defoaming, preventing foam from accumulating and overflowing or carrying unseparated light impurities into the subsequent purification process, thus ensuring the continuous and stable operation of the multi-stage separation and purification of collagen peptides. At the same time, the defoaming mechanism and the separation mechanism are coaxially linked, making the start-up, speed adjustment and shutdown control of the equipment more unified and convenient.

[0043] In an embodiment of the present invention, the flow guide plate 71 is provided with liquid inlet grooves 711 in an annular and equally spaced manner, and the flow guide plate 71 is also provided with oblique flow holes 712 in an annular and equally spaced manner. The bubble-extinguishing plate 72 is arc-shaped and inwardly folded, and the inner wall of the bubble-extinguishing plate 72 is fixedly provided with swirling blades 721 in a ring at equal intervals.

[0044] In the initial feeding stage of the equipment, the enzymatic hydrolysate enters the enzymatic hydrolysis tank 1 through the inlet tank 711 and the guide plate 71. At this stage, the inlet tank 711 only serves as an initial liquid passage and does not participate in the defoaming process. After the equipment is running normally, the drive rod assembly 61 drives the guide plate 71 to rotate at high speed. The foam generated in the upper part of the enzymatic hydrolysis tank 1 is guided to the edge of the guide plate 71 by the inclined flow holes 712 under the action of centrifugal force and is thrown towards the fixed defoaming plate 72. The defoaming plate 72 is arc-shaped and inwardly folded. Its arc-shaped inwardly folded structure gathers the thrown foam inward and guides the foam to the inner wall of the defoaming plate 72. When the foam touches the ring-shaped equidistant fixed bubble blades 721 under high speed, it is instantly broken by mechanical cutting and impact. The gas in the bubble escapes and the liquid phase falls back into the enzymatic hydrolysis tank 1.

[0045] It is important to note that the foam is directed by the inclined flow holes 712 to prevent foam accumulation in the central area of ​​the guide plate 71; the arc-shaped inward design of the defoaming plate 72 forms a foam accumulation cavity, which significantly increases the contact probability and collision speed between the foam and the vortex blades 721, thus greatly improving the defoaming efficiency; the vortex blades 721 are arranged in a ring with equal spacing, forming a continuous cutting interface in the circumferential direction, ensuring that the foam can uniformly contact the blades to complete the defoaming regardless of the rotation speed of the guide plate 71; the entire defoaming process utilizes the rotational power of the multi-stage separation mechanism 6 itself, without additional energy consumption, effectively suppressing the interference of foam accumulation at the top of the enzymatic hydrolysis tank 1 on the discharge and separation purification, and ensuring the continuity and stability of the multi-stage separation and purification operation of collagen peptides.

[0046] Working principle: This embodiment provides a method for using a multi-stage separation and purification device for collagen peptides, including the following steps: Step 1: The external power mechanism motor drives the main gear disk 611 to rotate through gear meshing. The main gear disk 611 drives the main shaft 612 to rotate synchronously at the bottom of the enzymatic hydrolysis tank 1. The drive rod group 61 drives the liquid guide cylinder 64, the fixed bearing sleeve 631 and the diversion plate 71 fixedly sleeved on it to rotate together. Step 2: The enzymatic hydrolysis stock solution is fed into the feed inlet 2 and then evenly guided into the enzymatic hydrolysis tank 1 by the separator 5. During the initial discharge, the enzymatic hydrolysis solution passes downward through the inlet groove 711 on the guide plate 71 and enters the multi-stage separation mechanism 6. Step 3: The drive rod assembly 61 drives the centrifugal inner ball assembly 63 to rotate inside the fixed cylinder assembly 62. Under the action of centrifugal force, the centrifugal ball petal 635 drives the movable bearing sleeve 632 to slide axially against the elastic force of the spring 633 through the connecting rod unit 634, so that the centrifugal ball petal 635 opens radially and forms a variable gap extrusion grinding cavity with the inner wall of the outer straight cylinder 623 and the outer hemispherical cylinder 624 of the fixed cylinder assembly 62. Step 4: Adjust the rotation speed of drive rod assembly 61 according to the type of impurities in the raw materials: If the material is hard, such as bone residue, keep the rotation speed low and the gap between the extrusion and grinding chambers is relatively large. The arc blade 6352 retracts into the slot 6351 under the tension of the elastic telescopic rod 6354. The outer surface of the centrifugal ball 635 cooperates with the inner wall of the fixed cylinder group 62 to perform high-intensity extrusion, grinding and crushing of the bone residue. If it is a collagen fiber cluster, the speed is increased to a high speed, the gap between the extrusion and grinding chambers is narrowed, and the arc blade 6352 is thrown out from the groove 6351 under the action of a large centrifugal force, overcoming the tension of the elastic telescopic rod 6354, and performing high-speed cutting, deaggregation and dispersion of the entangled collagen fibers. Step 5: After being squeezed, ground and chopped, the enzymatic hydrolysate passes through the filter holes on the fixed cylinder group 62, the primary coarse filter holes of the outer hemispherical cylinder 624 and the secondary fine filter holes of the outer straight cylinder 623 under the action of centrifugal force, and enters the enzymatic hydrolysis tank 1 cavity to complete solid-liquid separation. The clarified liquid is finally discharged from the discharge port 4. Step 6: During enzymatic hydrolysis, the foam generated rises to the top of the enzymatic hydrolysis tank 1. The rotating guide plate 71 guides the foam to the edge through the inclined flow holes 712 and throws it towards the fixed defoaming plate 72. The arc-shaped inward-turning defoaming plate 72 gathers the foam. Under high-speed movement, the foam touches the swirl blades 721 arranged in a ring at equal intervals on the inner wall of the defoaming plate 72, and the bubbles burst. The liquid phase falls back into the enzymatic hydrolysis tank 1 to continue to participate in separation and purification.

[0047] The embodiments disclosed in this invention are preferred embodiments, but are not limited thereto. Those skilled in the art can easily understand the spirit of this invention based on the above embodiments and make different extensions and variations, but as long as they do not depart from the spirit of this invention, they are all within the protection scope of this invention.

Claims

1. A multi-stage separation and purification device for collagen peptides, characterized in that, The enzymatic hydrolysis tank (1) is provided with a multi-stage separation mechanism (6) at the bottom of the enzymatic hydrolysis tank (1). A linkage defoaming mechanism (7) is provided on the inner wall of the enzymatic hydrolysis tank (1) at the top of the multi-stage separation mechanism (6). The bottom of the linkage defoaming mechanism (7) is fixedly connected to the multi-stage separation mechanism (6). The multi-stage separation mechanism (6) includes a drive rod assembly (61), a fixed cylinder assembly (62), and a centrifugal inner ball assembly (63). The drive rod assembly (61) is rotatably inserted into the bottom of the enzymatic hydrolysis tank (1). The fixed cylinder assembly (62) is fixedly installed on the inner wall of the enzymatic hydrolysis tank (1). The centrifugal inner ball assembly (63) is sleeved on the drive rod assembly (61) near the inside of the fixed cylinder assembly (62). The drive rod assembly (61) drives the centrifugal inner ball assembly (63) to rotate synchronously within the fixed cylinder assembly (62). The centrifugal inner ball assembly (63) can radially open with the centrifugal force generated by the rotation. After opening, the centrifugal inner ball assembly (63) and the inner wall of the fixed cylinder assembly (62) form a variable gap extrusion grinding chamber, which is used to crush and refine large bone fragments and undecomposed materials in the collagen peptide hydrolysate. The centrifugal inner ball group (63) has at least two working states by adjusting the fit gap with the inner wall of the fixed cylinder group (62): one is the bone residue crushing state, in which the gap is narrowed and used to crush hard bone residue and blocky materials by high-intensity extrusion grinding; the other is the fiber cutting state, in which the gap is adapted and adjusted and used to cut, depolymerize and disperse collagen fibers that are entangled.

2. The multi-stage separation and purification equipment for collagen peptides according to claim 1, characterized in that, The enzymatic hydrolysis tank (1) has an inlet (2) at the top, a base (3) at the bottom, a discharge port (4) on the outer side of the bottom, and a separatory plate (5) at the top inside the enzymatic hydrolysis tank (1).

3. The multi-stage separation and purification equipment for collagen peptides according to claim 1, characterized in that, The multi-stage separation mechanism (6) also includes a liquid guide tube (64), which is fixedly sleeved on the drive rod assembly (61).

4. The multi-stage separation and purification equipment for collagen peptides according to claim 1, characterized in that, The drive rod assembly (61) includes a main gear plate (611) and a main shaft (612). The main shaft (612) is rotatably inserted into the bottom end of the enzymatic hydrolysis tank (1). The main gear plate (611) is fixedly sleeved on the bottom end of the main shaft (612). The main gear plate (611) is driven by an external power mechanism.

5. The multi-stage separation and purification equipment for collagen peptides according to claim 1, characterized in that, The fixed cylinder assembly (62) includes a bottom cylinder (621), an inner support rod (622), an outer straight cylinder (623), an outer hemispherical cylinder (624), and a bushing (625). The bottom cylinder (621) is fixedly disposed on the inner wall of the enzymatic hydrolysis tank (1). The bushing (625) is rotatably sleeved on the drive rod assembly (61). The inner support rod (622) is arranged in a ring at equal intervals on the inner wall of the bottom cylinder (621). The end of the inner support rod (622) away from the bottom cylinder (621) is connected to the bushing (625). The outer straight cylinder (623) is fixedly disposed on the top of the bottom cylinder (621). The outer hemispherical cylinder (624) is fixedly disposed on the outer straight cylinder (623).

6. The multi-stage separation and purification equipment for collagen peptides according to claim 1, characterized in that, The centrifugal inner ball assembly (63) includes a fixed sleeve (631), a movable sleeve (632), a spring (633), a connecting rod unit (634), and a centrifugal ball petal (635). The fixed sleeve (631) is fixedly sleeved on the drive rod assembly (61), and the movable sleeve (632) is movably sleeved on the drive rod assembly (61). One end of the spring (633) is fixedly connected to the fixed sleeve (631), and the other end of the spring (633) is fixedly connected to the movable sleeve (632). One end of the connecting rod unit (634) is hinged to the fixed sleeve (631), and the other end of the connecting rod unit (634) is hinged to the movable sleeve (632). The centrifugal ball petal (635) is fixedly connected to the connecting rod unit (634).

7. The multi-stage separation and purification equipment for collagen peptides according to claim 6, characterized in that, The connecting rod unit (634) includes a main connecting rod (6341) and a secondary connecting rod (6342). One end of the main connecting rod (6341) is hinged to the fixed bearing sleeve (631), and the other end of the main connecting rod (6341) is fixedly connected to the centrifugal ball petal (635). One end of the secondary connecting rod (6342) is hinged to the movable bearing sleeve (632), and the other end of the secondary connecting rod (6342) is hinged to the main connecting rod (6341).

8. The multi-stage separation and purification equipment for collagen peptides according to claim 6, characterized in that, The centrifugal ball petal (635) has fan-shaped slots (6351) at equal intervals. An arc blade (6352) is movably inserted into the slot (6351). An arc plate (6353) is fixedly installed on the centrifugal ball petal (635). Several elastic telescopic rods (6354) are fixedly installed on the arc plate (6353). The end of the elastic telescopic rod (6354) away from the arc plate (6353) is fixedly connected to the arc blade (6352).

9. The multi-stage separation and purification equipment for collagen peptides according to claim 1, characterized in that, The linkage defoaming mechanism (7) includes a flow guide plate (71) and a defoaming plate (72). The flow guide plate (71) is fixedly sleeved on the top of the drive rod assembly (61), and the defoaming plate (72) is fixedly installed on the inner wall of the enzymatic hydrolysis tank (1) at the position of the flow guide plate (71).

10. The multi-stage separation and purification equipment for collagen peptides according to claim 9, characterized in that, The flow guide plate (71) is provided with liquid inlet grooves (711) in a ring at equal intervals, and the flow guide plate (71) is also provided with oblique flow holes (712) in a ring at equal intervals. The bubble-extinguishing plate (72) is arc-shaped and inwardly folded, and the inner wall of the bubble-extinguishing plate (72) is fixedly provided with swirling blades (721) at equal intervals in a ring.

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