Personal care composition

Abstract

This document describes personal care compositions comprising surfactant blends, wherein the personal care compositions are free of sulfates and betaine, and wherein the personal care compositions comprise surfactant blends containing anionic surfactants and amphoteric surfactants, as well as at least one preservative. Methods for preparing and using the personal care compositions are also disclosed herein.

Description

Technical Field

[0001] This invention relates to personal care compositions and methods for preparing and using personal care compositions. Background Technology

[0002] Many personal care compositions available on the market today contain a variety of ingredients that contribute to high production costs and processing times, as well as increased risk of allergens and irritants for certain populations. Furthermore, a variety of surfactants are used in personal care and home care products to impart foaming properties, and the use of some surfactants may raise concerns about environmental impact in addition to causing dermatological problems.

[0003] Many surfactants commonly used in personal care compositions contain sulfates. Sulfates are relatively inexpensive and can be easily thickened with common ingredients such as sodium chloride. However, sulfates, including common sulfates such as sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES), can be irritating to the skin, causing dryness and irritation. Many consumers may seek gentle, sulfate-free options to help maintain the skin's natural moisture barrier. Many consumers may also have sensitive skin or conditions such as eczema and psoriasis and therefore seek sulfate-free products that reduce the risk of irritation and discomfort.

[0004] Cocamidopropyl betaine (CAPB) is another surfactant ingredient used in many personal care compositions, including shampoos, body gels, shower gels, and hand soaps, making it a common surfactant used in the skin care industry. However, CAPB has been identified as a potential allergen, leading to a growing preference among consumers for betaine-free personal care compositions.

[0005] Therefore, there is a need for effective personal care compositions that exhibit sufficient foaming properties, stability, viscosity, and micro-robustness without significantly irritating the skin and are free of concerning ingredients such as sulfates and betaine. Summary of the Invention

[0006] This disclosure relates to personal care compositions, such as liquid cleaning compositions, comprising a surfactant blend and at least one preservative, said surfactant blend comprising or consisting of anionic surfactants and amphoteric surfactants, wherein the personal care composition is free of or substantially free of sulfates and betaines, including SLS, SLES and CAPB.

[0007] In several embodiments, the anionic surfactant is an acyl taurate or a salt thereof, such as methyl cocoyl taurate (e.g., sodium methyl cocoyl taurate). In some embodiments, the anionic surfactant is present in the personal care composition in an amount ranging from about 1% to about 10% by weight, for example from about 1% to about 5% by weight or from about 3.5% to about 4% by weight, based on the total weight of the personal care composition.

[0008] According to certain embodiments disclosed herein, the amphoteric surfactant is an amphoteric acetate, and in some embodiments, the amphoteric surfactant is selected from sodium cocoamphoacetate or sodium lauroylamphoacetate. In some exemplary embodiments, the amphoteric surfactant is present in the personal care composition in an amount ranging from about 1% to about 10% by weight, for example, from about 4% to about 7% by weight or from about 5% to about 6% by weight, based on the total weight of the personal care composition.

[0009] In some embodiments, at least one preservative is selected from lactic acid, sodium benzoate, sodium lactate and combinations thereof, preferably lactic acid, and in some embodiments, at least one preservative is present in the personal care composition in an amount ranging from about 1% to about 5% by weight, for example from about 1% to about 2% by weight, relative to the total weight of the personal care composition.

[0010] In some embodiments, the personal care composition further comprises at least one liquid carrier, such as water. In several embodiments of this disclosure, the personal care composition further comprises at least one fragrance agent, and in several embodiments, the at least one fragrance agent is present in an amount of about 0.3% by weight to about 1.3% by weight, for example, about 0.4% by weight to about 0.9% by weight, based on the total weight of the personal care composition. In some embodiments, the personal care composition further comprises at least one foaming agent.

[0011] In some embodiments, the viscosity of the personal care composition is in the range of about 3,000 cps to about 6,000 cps, for example, about 4,000 cps to about 5,500 cps, about 4,500 cps to about 5,250 cps, or about 5,000 cps.

[0012] In some aspects of this disclosure, the personal care composition comprises a surfactant blend consisting of an acyl taurate and an amphoteric acetate, such as sodium methyl cocoyl taurate and sodium cocoamphoacetate, and in some aspects, the amphoteric surfactant and the anionic surfactant are present in a weight ratio of about 1:1 to about 5:1, for example, about 1:1 to about 2:1, about 1.4:1, about 1.5:1, or about 1.46:1.

[0013] In some embodiments, the personal care composition is a bath soap, bath gel, shampoo, conditioner, shower gel, or skin cleanser, preferably a shower gel, and in some embodiments, the micro robustness index of the personal care composition is at least about 0.85, for example, at least about 1.0, at least about 1.2, at least about 1.3, or at least about 1.4. In some embodiments, the pH of the personal care composition is in the range of about 4 to about 5.

[0014] Other embodiments of this disclosure include a method of manufacturing a personal care product comprising the personal care composition disclosed herein, the method comprising: blending at least one anionic surfactant, at least one amphoteric surfactant, at least one preservative and any other optional ingredients together in a liquid carrier to form a personal care composition as disclosed herein (e.g., a sulfate- and betaine-free personal care composition); and adding a predetermined volume of the personal care composition to a container to form a personal care product.

[0015] Other applicable areas of this disclosure will become apparent from the detailed description provided below. It should be understood that while the detailed description and specific examples indicate embodiments of this disclosure, they are for illustrative purposes only and are not intended to limit the scope of this disclosure. Attached Figure Description

[0016] The features and advantages of this disclosure will be apparent from the following more detailed description of certain embodiments and as illustrated in the accompanying drawings, in which:

[0017] Figure 1 This is a graph showing the foaming curves of the control formulation (“PO Olive BW”) and prototype 6 (“New Sulfate-Free BW”) over time, as described in Example 3.

[0018] Figure 2 This is a graph showing the maximum foam volume achieved by the control formulation (“PO Olive BW”) and prototype 6 (“New Sulfate-Free BW”), as described in Example 3.

[0019] Figure 3 This is a graph showing the foaming rate (mm / s) of the control formulation (“PO Olive BW”) and prototype 6 (“New Sulfate-Free BW”), as described in Example 3.

[0020] Figure 4 This shows the per mm of the control formulation (“PO Olive BW”) and prototype 6 (“New Sulfate-Free BW”). 3 The initial bubble count is shown in the graph as described in Example 3.

[0021] Figure 5 This is a graph showing the initial bubble size (μm) of the control formulation (“PO Olive BW”) and prototype 6 (“New Sulfate-Free BW”), as described in Example 3.

[0022] It should be understood that the aspects are not limited to the components, arrangements and means shown in the accompanying drawings. Detailed Implementation

[0023] The following description of several implementations is merely exemplary in nature and is in no way intended to limit the content of this disclosure, its application, or its use.

[0024] As used throughout, ranges are used as abbreviations to describe the individual values ​​within a range and for each value. Any value within a range may be chosen as an endpoint of the range. Furthermore, all references cited herein are incorporated herein by reference in their entirety. In the event of any conflict between definitions in this disclosure and those in the cited references, the definitions in this disclosure shall prevail.

[0025] Unless otherwise stated, all percentages and quantities expressed herein and elsewhere in the specification shall be understood as weight percentages. The quantities given are based on the effective weight of the material. According to this application, the term "about" means + / - 10% or less of a reference value. According to this application, the terms "substantially free of" or "free of" mean less than about 0.1 wt% based on the total reference value, such as less than about 0.01 wt%, less than about 0.001 wt%, less than about 0.0001 wt%, or an undetectable amount.

[0026] As used herein, the use of compounds containing several isomers or stereoisomers includes all isomer forms of that compound. When referring to chemical structures and names, the symbols “C,” “H,” and “O” refer to carbon, hydrogen, and oxygen, respectively. The symbols “-,” “=,” and “≡” refer to single, double, and triple bonds, respectively. For readability purposes, chemical functional groups are presented in their adjective form; for each adjective, the word “group” is assumed to follow. For example, the adjective “alkyl” without a noun should be interpreted as “alkyl group.”

[0027] Any member of the species list used to exemplify or define a genus may be distinct from, overlap with, be a subset of, be equivalent to, be nearly identical to, or be identical to any other member of the species list. Furthermore, unless explicitly stated otherwise, for example when describing the Markush Formation, the list of species used to define or exemplify a genus is open-ended, and it is permissible for other species to exist that define or exemplify the genus that are exactly as good as or better than any other species listed.

[0028] All components and elements affirmatively set forth in this disclosure may be negatively excluded from the claims. In other words, the personal care compositions of this disclosure may contain no or substantially no components and elements affirmatively recited throughout this disclosure. In some cases, the personal care compositions of this disclosure may contain substantially no non-incidental amounts of the ingredients or compounds described herein. A non-incidental amount of an ingredient or compound is the amount of that ingredient or compound added alone to the personal care composition. For example, a personal care composition may contain substantially no non-incidental amounts of a certain ingredient or compound, although such an ingredient or compound may be present as part of raw materials included in a blend of two or more compounds.

[0029] Some of the identified categories of components may overlap. In cases where overlap is possible and a personal care composition contains two components (or more than two overlapping components), the overlapping compounds do not represent more than one component. For example, caprylyl glycol can be characterized as both a moisturizer and a preservative. If a particular personal care composition contains both a moisturizer and a preservative, caprylyl glycol will be used only as either a moisturizer or a preservative—not both.

[0030] As used herein, the terms “composition” and “formulation” are used interchangeably in the product information.

[0031] This disclosure relates to aspects of personal care compositions. Personal care compositions may comprise surfactant blends. In some embodiments, the personal care composition may comprise a surfactant blend containing at least two surfactants, such as at least three surfactants, and in some embodiments, the personal care composition may comprise a surfactant blend consisting of two or three surfactants. In some embodiments, the personal care composition comprises a surfactant blend containing at least one anionic surfactant and at least one amphoteric surfactant, or consisting of at least one anionic surfactant and at least one amphoteric surfactant, and in some embodiments, the personal care composition is free of or substantially free of sulfates, such as SLS and SLES, and / or free of or substantially free of betaines, such as CAPB.

[0032] In some embodiments, the personal care composition may be a cosmetically acceptable composition that can be used to cleanse skin surfaces, particularly human skin surfaces, and contains environmentally safe ingredients, i.e., ingredients that can be broken down into substantially harmless substances in wastewater treatment plants, and has a protective effect on the skin (e.g., against irritation and dryness).

[0033] In some embodiments, the personal care compositions may also provide emollient effects, as well as excellent cosmetic and physical stability. In some embodiments, the personal care compositions disclosed herein impart conditioning, smoothing, and / or emollient properties to the skin, and thus reduce the tendency for the skin to become dry, irritated, or otherwise traumatized.

[0034] As used herein, the term "skin surface" refers to the outermost surface of the body and includes both intact skin and injured skin surfaces, mucous membranes, and mucous membranes. In a broad sense, the term "skin surface" encompasses both the epidermis and the dermis of the skin. The epidermis is the outer (epithelial) layer, while the deeper connective tissue layer of the skin is called the dermis. Skin can have a thick or thin epidermis and is therefore generally classified as thick skin or thin skin. In this context, the term "skin" includes both thick and thin skin.

[0035] As used herein, the term "soap" is given a broad meaning and is intended to cover agents used for cleaning hands, hair, and / or the body, including cosmetic or detergent substances as described in 21C.FR701.20, and in particular products commonly referred to as liquid hand soaps and shower gels.

[0036] Surfactant blends

[0037] In some embodiments of this disclosure, the personal care composition comprises a surfactant blend that provides a significant skin feel and can help promote end-user benefits such as desired foaming properties, moisturizing effects, fragrance, skin hydration, etc., while reducing formulation costs and / or simplifying formulation processes, and is gentle and non-irritating to the skin, including sensitive skin. In some embodiments, the surfactant blend is sulfate-free (e.g., SLS and SLES) and betaine-free (e.g., CAPB).

[0038] In some embodiments, the surfactant blend in the personal care composition comprises at least two surfactants, wherein the first surfactant is an anionic surfactant. As used herein, "anionic surfactant" means those surfactant or detergent compounds that, in their molecular structure, contain an organic hydrophobic group typically containing 8 to 26 carbon atoms or typically 10 to 18 carbon atoms and at least one water-solubilizing group to form a water-soluble detergent. Typically, the hydrophobic group will contain C8-C4 atoms. 22 Alkyl or acyl groups. Such surfactants are used in the form of water-soluble salts, and the salt-forming cations can be selected from sodium, potassium, ammonium, magnesium, and mono-C2-C3 alkanolammonium, di-C2-C3 alkanolammonium, or tri-C2-C3 alkanolammonium, with sodium, magnesium, and ammonium cations being the most commonly chosen salt-forming cations.

[0039] Examples of anionic surfactants include, but are not limited to, linear C8-C. 18 Alkyl ether sulfates, ether sulfates, and their sodium, potassium, ammonium, and ethanol ammonium salts. Anionic ether sulfates have the formula R(OC₂H₄). n OSO3M, where n is 1 to 12 or 1 to 5, and R is an alkyl, alkylaryl, acyl, or alkenyl group having 8 to 18 carbon atoms, for example, C 12 -C 14 Or C 12 -C 16 The alkyl group, and M, are solubilizing cations selected from sodium, potassium, ammonium, magnesium, and monoethanolammonium, diethanolammonium, and triethanolammonium ions. Exemplary alkyl ether sulfates contain 12 to 15 carbon atoms in their alkyl groups, such as sodium lauryl ether (2EO) sulfate or sodium lauryl ether (1EO) sulfate. In some embodiments, the anionic surfactants that may be used in the personal care compositions of this disclosure are free of any such sulfates, such as SLES 1EO or SLES 2EO.

[0040] SLES is an anionic surfactant widely used as a primary surfactant in cleaning products and personal care compositions. In addition to its ability to clean surfaces (e.g., skin), SLES also possesses emulsifying and foaming properties. SLES raw materials contain trace amounts of 1,4-dioxanone. Alkane, which is a chemical substance formed as a byproduct during the ethoxylation step. The more ethoxy groups present, the more 1,4-dialkyl groups are present in the SLES raw material. The higher the level of alkyl groups, the better. For example, SLES2EO (SLES with an average degree of ethoxylation of 2) contains up to about 50 ppm of 1,4-dialkyl groups. Alkane. If the composition contains 7% to 18% SLES2EO, then the composition will contain more than 1 ppm of 1,4-dialkyl. Alkane. 1,4-Dialkyl Alkane is a possible carcinogen. 1,4-Dialkylene oxide (DIO) Alkanes are very stable and do not degrade naturally. Furthermore, it is impossible to eliminate 1,4-dialkyl during water treatment. Alkane. The impact of using compositions containing SLES on groundwater contamination has been recognized. The U.S. Food and Drug Administration (FDA) recommends monitoring 1,4-dialkyl in products. The level of alkyl groups, and encourages manufacturers to remove 1,4-dialkyl groups. Alkane. New York banned the sale of alkane containing more than 2 ppm of 1,4-dialkyl by the end of 2022. Household cleaning and personal care products containing more than 1 ppm of 1,4-dialkyl will be banned from sale by the end of 2023. Alkane-based household cleaning and personal care products. Therefore, in some embodiments, it may be desirable to formulate personal care compositions that are free of or substantially free of SLES.

[0041] Eliminating or reducing 1,4-dioxanone in certain compositions (e.g., home care compositions) One approach is to use sodium lauryl sulfate (unethoxylated) instead of SLES. However, such compositions containing sodium lauryl sulfate (SLS) may have poor stability at low temperatures, and the user's skin may be irritated after contact with the composition. Therefore, in some embodiments, the personal care compositions disclosed herein are SLS-free.

[0042] In some embodiments, the anionic surfactant is a non-sulfate anionic surfactant. In some embodiments, the non-sulfate surfactant is an acyl taurate (e.g., methyl cocoyl taurate) or a salt thereof, such as sodium methyl cocoyl taurate.

[0043] Anionic surfactants are preferably used as sodium salts, but can also be used as other alkali metal or alkaline earth metal salts such as magnesium salts, as well as in the form of ammonium salts or monoalkylammonium salts, dialkylammonium salts, trialkylammonium salts or tetraalkylammonium salts.

[0044] In some embodiments, the anionic surfactant may be selected from acyl taurate salts having a structure according to the following formula:

[0045]

[0046] Where R1 is a saturated or unsaturated, straight or branched alkyl chain having 6 to 18 carbon atoms, R2 is H or methyl, and M is M. + The acyl taurate is H, sodium, or potassium (e.g., sodium methylcocoyl taurate). Examples of acyl taurates include sodium cocoyl taurate, potassium cocoyl taurate, potassium methyl cocoyl taurate, sodium hexanoyl methyl taurate, sodium cocoyl taurate, sodium lauroyl taurate, sodium methyl cocoyl taurate (SMCT), sodium methyl lauroyl taurate, sodium methyl myristoyl taurate, sodium methyl oleoyl taurate, sodium methyl palmitoyl taurate, sodium methyl stearyl taurate, and combinations thereof. In some embodiments, the personal care composition comprises sodium lauroyl methyl taurate (or sodium methyl lauroyl taurate), sodium methyl cocoyl taurate (SMCT), or combinations thereof. In at least one preferred embodiment, the surfactant system comprises sodium methyl cocoyl taurate.

[0047] In some embodiments, based on the total weight of the personal care composition, an anionic surfactant (e.g., sodium methyl cocoyl taurate) may be present in the personal care composition disclosed herein in amounts ranging from about 0.01 wt% to about 6 wt%, such as about 0.1 wt% to about 5 wt%, about 1 wt% to about 5 wt%, about 1.5 wt% to about 5 wt%, about 2 wt% to about 5 wt%, about 2.5 wt% to about 5 wt%, about 3 wt% to about 5 wt%, about 3.5 wt% to about 5 wt%, about 4 wt% to about 5 wt%, about 1 wt% to about 4.5 wt%, about 1.5 wt% to about 4.5 wt%, about 2 wt% to about 4.5 wt%, about 2.5 wt% to about 4.5 wt%, about 3 wt% to about 4.5 wt%, about 3.5 wt% to about 4.5 wt%, about 4 wt% to about 4.5 wt%, or about 3.5 wt% to about 4 wt%. In some embodiments, based on the total weight of the personal care composition, the anionic surfactant disclosed herein (e.g., sodium methyl cocoyl taurate) may be present in the personal care composition disclosed herein in amounts of about 3.5 wt%, about 3.6 wt%, about 3.7 wt%, about 3.8 wt%, about 3.9 wt%, about 4 wt%, about 4.1 wt%, about 4.2 wt%, about 4.3 wt%, about 4.4 wt%, or about 4.5 wt%.

[0048] In some embodiments, the surfactant blends of the personal care compositions disclosed herein include a second surfactant. The second surfactant in the surfactant blend may include an amphoteric compound, an amphoteric compound, and / or combinations thereof. Suitable amphoteric or amphoteric surfactants used in the compositions herein include those known for personal care cleaning, and in some embodiments, the amphoteric or amphoteric surfactant is not betaine or a derivative thereof.

[0049] Suitable amphoteric surfactants for use in the compositions are known in the art and include those surfactants widely described as derivatives of aliphatic secondary and tertiary amines, wherein the aliphatic group may be linear or branched, and wherein one of the aliphatic substituents comprises about 8 to about 18 carbon atoms, and another comprises an anionic group, such as a carboxyl group, sulfonate group, sulfate group, phosphate group, or phosphonate group. Suitable examples of such amphoteric surfactants include, but are not limited to, sodium cocoaminopropionate, sodium cocoaminodipropionate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate, sodium cocoamphoacetate. Ammonium cocoaminopropionate, Ammonium cocoaminodipropionate, Ammonium cocoamphoacetate, Ammonium cocoamphohydroxypropylsulfonate, Ammonium cocoamphopropionate, Ammonium zeatinomeamphopropionate, Ammonium laurylaminopropionate, Ammonium lauroamphoacetate, Ammonium lauroamphohydroxypropylsulfonate, Ammonium lauroamphopropionate, Ammonium zeatinomeamphopropionate, Ammonium lauryliminodipropionate, Triethanolamine cocoaminopropionate, Triethanolamine cocoaminodipropionate, Triethanolamine cocoamphoacetate, Triethanolamine cocoamphohydroxypropylsulfonate Ethanolamine, Triethanolamine Cocoamphopropionate, Triethanolamine Zeadhopropionate, Triethanolamine Laurylaminopropionate, Triethanolamine Lauroamphoacetic Acid, Triethanolamine Lauroamphohydroxypropylsulfonic Acid, Triethanolamine Lauroamphopropionate, Triethanolamine Zeadhopropionate, Triethanolamine Lauryliminodipropionate, Cocoamphodipropionate, Disodium Decanoamphodiacetate, Disodium Decanoamphodipropionate, Disodium Octanoamphodiacetate, Disodium Octanoamphodipropionate, Cocoamphocarboxyethylhydroxypropylsulfonic acid Disodium cocoamphodiacetate, disodium cocoamphodiapropionate, disodium dicarboxyethyl cocoylpropanediamine, disodium lauryl ether-5-carboxyamphodiacetate, disodium lauryliminodiapropionate, disodium lauroylamphodiacetate, disodium lauroylamphodiapropionate, disodium oleoylamphodiapropionate, disodium PPG-2-isodecyl alcohol polyether-7-carboxyamphodiacetate, laurylaminopropionic acid, lauroylamphodiapropionate, laurylaminopropylglycine, lauryl diethylenediaminoglycine, and combinations thereof. In some embodiments, the amphoteric surfactant is sodium cocoamphodiacetate.

[0050] Amphoteric surfactants suitable for use in the compositions are well known in the art and include those widely described as aliphatic quaternary ammonium and phosphorus surfactants. and sulfur The surfactants that are derivatives of the compounds, wherein the aliphatic groups may be linear or branched, and wherein one of the aliphatic substituents comprises about 8 to about 18 carbon atoms and another comprises an anionic group, such as a carboxyl group, a sulfonate group, a sulfate group, a phosphate group, or a phosphonate group. In some embodiments, the personal care compositions disclosed herein are free of or substantially free of amphoteric surfactants. Amphoteric surfactants include, but are not limited to, cocamidoethyl betaine, cocamidopropylamine oxide, cocamidopropyl betaine, cocamidopropyl dimethylaminohydroxypropyl hydrolyzed collagen, cocamidopropyl dimethylammonium hydroxypropyl hydrolyzed collagen, cocamidopropyl hydroxysulfonyl betaine, cocamidopropyl amphoteric propionate, cocamidopropyl, cocamidopropyl hydroxysulfonyl betaine, cocamidopropyl betaine, cocamidopropyl hydroxysulfonyl betaine, cocamidopropyl hydroxysulfonyl betaine, and combinations thereof. In some exemplary embodiments, the personal care composition is free of cocamidopropyl betaine.

[0051] In some embodiments, the amphoteric surfactant is sodium cocoamphoacetate, and the composition is free of or substantially free of betaine, such as cocamidopropyl betaine. In some embodiments, the personal care compositions disclosed herein comprise surfactant blends comprising anionic surfactants (e.g., SMCT) and amphoteric surfactants (e.g., sodium cocoamphoacetate).

[0052] Amphoteric surfactants (e.g., sodium cocoamphoacetate) may be present in the personal care compositions disclosed herein in any suitable amount. In some embodiments, based on the total weight of the personal care composition, the amphoteric surfactant (e.g., sodium cocoamphoacetate) is present in the personal care compositions disclosed herein in amounts ranging from about 1 wt% to about 10 wt%, such as about 1 wt% to about 9 wt%, about 2 wt% to about 9 wt%, about 3 wt% to about 9 wt%, about 4 wt% to about 9 wt%, about 5 wt% to about 9 wt%, about 6 wt% to about 9 wt%, about 1 wt% to about 7 wt%, about 2 wt% to about 7 wt%, about 3 wt% to about 7 wt%, about 4 wt% to about 7 wt%, about 5 wt% to about 7 wt%, about 1 wt% to about 6 wt%, about 2 wt% to about 6 wt%, about 3 wt% to about 6 wt%, about 4 wt% to about 6 wt%, or about 5 wt% to about 6 wt%. In some embodiments, based on the total weight of the personal care composition, the amphoteric surfactant (e.g., sodium cocoamphoacetate) disclosed herein may be present in the personal care composition in the following amounts: about 5.0 wt%, about 5.1 wt%, about 5.2 wt%, about 5.3 wt%, about 5.4 wt%, about 5.5 wt%, about 5.6 wt%, about 5.7 wt%, about 5.8 wt%, about 5.9 wt%, or about 6.0 wt%.

[0053] In some embodiments of this disclosure, the personal care composition comprises anionic surfactant and amphoteric surfactant, and in some embodiments, the ratio of the amphoteric surfactant to the anionic surfactant can be in the range of about 1:1 to about 5:1, for example, about 1:1 to about 4:1, about 1:1 to about 3:1, or about 1:1 to about 2:1. In some embodiments, the ratio of the amphoteric surfactant to the anionic surfactant in the personal care composition is about 1:1, about 1.1:1, about 1.2:1, about 1.3:1, about 1.4:1, about 1.5:1, about 1.6:1, about 1.7:1, about 1.8:1, about 1.9:1, or about 2.0:1.

[0054] In several aspects of this disclosure, surfactant blends may also comprise nonionic surfactants, and in some embodiments, the personal care composition is free of nonionic surfactants. As used herein, "nonionic surfactant" generally refers to a compound produced by the condensation of an oxidized alkenyl group (which is inherently hydrophilic) with an organic hydrophobic compound that may be aliphatic or alkyl aromatic. Examples of nonionic surfactants include poloxamer (trade name...). Sales), polyoxyethylene, polyoxyethylene dehydrated sorbitol ester (by trade name) (sales), polyoxyethylene 40 hydrogenated castor oil, fatty alcohol ethoxylates, alkylphenol polyoxyethylene condensates, products derived from the condensation of ethylene oxide with (the reaction product of propylene oxide and ethylenediamine), aliphatic alcohol ethylene oxide condensates, alkyl polyglycosides (e.g., fatty alcohol ethers of polyglycosides, such as fatty alcohol ethers of polyglucosides, such as decyl ether, lauryl ether, octyl ether, octanoyl ether, myristyl ether, stearyl ether and other ethers, including such as octyl / octanoyl (C 8-10 ) glucoside, cocoyl (C 8-16 ) glucoside, decyl glucoside and lauryl (C 12-16 Alkyl glucosides include mixed ethers of glucosides, long-chain tertiary amine oxides, long-chain tertiary phosphine oxides, long-chain dialkyl sulfoxides, and mixtures of such substances. Alkyl glucosides are compounds produced by combining sugars such as glucose with fatty alcohols. Alkyl refers to unbranched or branched carbon chains. In some embodiments, the alkyl group is unbranched. The alkyl group can be saturated or unsaturated. In some embodiments, the alkyl group is saturated.

[0055] Alkyl glucosides can be C 8-25 Alkyl glucosides, such as C 8-18 Alkyl glucoside, C 10-18 Alkyl glucoside or C 10-16 Alkyl glucoside. In some embodiments, the alkyl glucoside is selected from decyl glucoside, octanoyl / octyl glucoside, lauryl glucoside, cocoyl glucoside, octyl glucoside, cetearyl glucoside, cetyl glucoside, hexadecyl glucoside, arachidonic glucoside, and combinations thereof. In some embodiments, the alkyl glucoside is selected from decyl glucoside, octanoyl / octyl glucoside, cocoyl glucoside, and combinations thereof.

[0056] In embodiments of this disclosure, based on the total weight of the personal care composition, the nonionic surfactant may be present in the personal care composition disclosed herein in amounts ranging from about 0 wt% to about 5 wt%, for example, 0.1 wt% to about 5 wt%, about 0.1 wt% to about 4 wt%, about 0.1 wt% to about 3 wt%, about 0.1 wt% to about 2 wt%, about 0.1 wt% to about 1.5 wt%, about 0.1 wt% to about 1.2 wt%, about 0.1 wt% to about 1 wt%, about 0.5 wt% to about 5 wt%, for example, about 0.5 wt% to about 4 wt%, about 0.5 wt% to about 3 wt%, about 0.5 wt% to about 2 wt%, about 0.5 wt% to about 1.5 wt%, about 0.5 wt% to about 1.2 wt%, about 0.5 wt% to about 1 wt%, about 1 wt% to about 1.5 wt%, or about 1 wt% to about 1.2 wt%. In some embodiments, the personal care composition may be free of or substantially free of nonionic surfactant.

[0057] In some embodiments of this disclosure, the personal care composition comprises a surfactant blend containing anionic surfactants and amphoteric surfactants, or a blend of anionic surfactants and amphoteric surfactants. In some embodiments, the personal care composition comprises a surfactant blend containing an acyl taurate (e.g., sodium methyl cocoyl taurate) and an acyl amphoteric acetate (e.g., sodium cocoyl amphoteric acetate), or a blend of an acyl taurate (e.g., sodium methyl cocoyl taurate) and an acyl amphoteric acetate (e.g., sodium cocoyl amphoteric acetate). In some embodiments, the personal care composition comprises a surfactant blend containing an acyl taurate (e.g., sodium methyl cocoyl taurate) and an acyl amphoteric acetate (e.g., sodium cocoyl amphoteric acetate), or a blend of an acyl taurate (e.g., sodium methyl cocoyl taurate) and an acyl amphoteric acetate (e.g., sodium cocoyl amphoteric acetate), and is free of or substantially free of sulfates and betaine.

[0058] At least one preservative

[0059] In other embodiments, the personal care composition may also contain at least one suitable preservative. Because the personal care compositions disclosed herein are sulfate-free and betaine-free, alternative surfactants (e.g., anionic surfactants such as SMCT and amphoteric surfactants such as amphoteric acetates) may not maintain sufficient micro-robustness. Therefore, the personal care compositions disclosed herein contain at least one preservative. A preservative is a compound added to a formulation to act as an antimicrobial agent and to prevent or inhibit spoilage of the formulation. Effective preservatives known in the art are acids such as lactic acid and / or citric acid, sodium lactate, benzalkonium chloride, benzyl ethylamine, chlorhexidine, phenol, m-cresol, benzyl alcohol, methylparaben, propylparaben, chlorobutanol, o-cresol, p-cresol, chlorocresol, phenylmercuric nitrate, thimerosal, benzoic acid, sodium benzoate, sodium salicylate, and various mixtures thereof.

[0060] When the composition contains at least one preservative, the total amount of preservative present can range from about 0.01% by weight to about 1% by weight, depending on the characteristics of the particular preservative selected and the amount required for effective preservation in a particular formulation. In some embodiments, the personal care composition contains at least one preservative selected from lactic acid, sodium lactate, sodium benzoate, and combinations thereof, and in some embodiments, the at least one preservative is lactic acid. In some embodiments, the preservative is present in the personal care composition in the following amounts based on the total weight of the personal care composition: about 0.1 wt% to about 5 wt%, for example, about 0.1 wt% to about 4 wt%, about 0.5 wt% to about 3 wt%, about 0.5 wt% to about 2.5 wt%, about 1 wt% to about 5 wt%, about 1 wt% to about 4 wt%, about 1 wt% to about 3 wt%, about 1 wt% to about 2.5 wt%, about 1.5 wt% to about 5 wt%, about 1.5 wt% to about 4 wt%, about 1.5 wt% to about 3 wt%, about 1.5 wt% to about 2.5 wt%, about 2 wt% to about 5 wt%, about 2 wt% to about 4 wt%, about 2 wt% to about 3 wt%, or about 2 wt% to about 2.5 wt%.

[0061] Antimicrobial activity can be measured by any means known in the art, including, for example, by performing microbial robustness testing and / or short-interval killing tests on the composition. As used herein, microbial robustness testing refers to a screening process used to assess the microbial robustness of a composition (e.g., a personal care composition as disclosed herein). Microbial robustness is a quantitative measure of a composition’s ability to resist microbial attack and encompasses both the kill rate of the bacterial inoculum and the total kill level. The quantitative measure can be expressed as the area under the curve (AUC). To calculate the microbial robustness index, the composition is challenged by inoculating it with a specific microorganism or a microbial bank. The challenged composition is sampled at selected time intervals (e.g., 0 h, 2 h, 4 h, 6 h, 24 h, 48 h, 72 h, and / or 96 h). Dilution and plating are performed to recover surviving microorganisms, and the logarithmic difference in bacterial counts (CFU / g) between the composition and the inoculum control is calculated over time to determine the AUC. In some embodiments disclosed herein, the micro robustness index of the personal care composition is at least about 0.85, such as at least about 0.90, at least about 0.95, 1.0, at least about 1.1, at least about 1.2, at least about 1.3, or at least about 1.4.

[0062] liquid carrier

[0063] The personal care compositions disclosed herein may comprise a liquid carrier. The liquid carrier may include one or more of a solvent, a diluent, or a combination thereof. The liquid carrier may include one or more of water, an alcohol (e.g., ethanol, isopropanol, or mixtures thereof), or mixtures thereof. In at least one embodiment, the carrier comprises water.

[0064] The amount of liquid carrier present in the personal care formulation can vary based on the total weight of the personal care composition, for example, between about 50% by weight and about 98% by weight, including all weight percent and subranges therebetween. In some embodiments, the amount of liquid carrier present in the personal care composition can range from about 55% by weight to about 93% by weight, for example, from about 60% by weight to about 80% by weight, from about 60% by weight to about 70% by weight, or from about 60% by weight to about 65% by weight, based on the total weight of the personal care composition.

[0065] Other ingredients

[0066] The personal care compositions disclosed herein may contain any additional ingredients known for use in personal care compositions. Other non-limiting examples of such personal care composition ingredients include thickeners, foaming agents, antibacterial agents, fragrances or aromas, colorants or dyes, conditioning agents, hair bleaching agents, moisturizers, emollients, pharmaceutically active substances, vitamins or nutrients, sunscreens, deodorants, plant extracts, nutrients, astringents, cosmetic particles, absorbent particles, adhesive particles, hair fixatives, fibers, reactants, skin brighteners, skin tanning agents, anti-dandruff agents, fragrances, exfoliants, acids, alkalis, humectants, enzymes, suspending agents, pH adjusters, hair dyes, perming agents, pigment particles, anti-acne agents, antimicrobial agents, exfoliating particles, hair growth or repair agents, insect repellents, shaving shampoos, cosolvents or other additional solvents, and similar other substances.

[0067] In some embodiments, the personal care composition may contain a thickener. The thickener may be selected from one or more polysaccharides. In some embodiments, the polysaccharide may include one or more of the following: xanthan gum, tragacanth gum, carrageenan gum (also referred to simply as "carrageenan"), alginate, agar, gum arabic, guar gum, gellan gum, pectin, cellulose, welan gum, dituan gum, locust bean gum extract from carob tree seeds, damar gum, kauri gum, spruce gum, gum derived from fenugreek, and anima gum (Western or Eastern).

[0068] In some embodiments, the personal care compositions disclosed herein further comprise at least one foam enhancer to increase the amount of foam. Any foam enhancer known in the art may be used in the embodiments disclosed herein. Examples of foam enhancers include, but are not limited to, fatty acid monoethanolamide, fatty acid diethanolamide, coconut oil monoethanolamide (CMEA), coconut oil diethanolamide (CDEA), and lauryl diethanolamide. In some embodiments, the personal care compositions disclosed herein contain no or substantially no foam enhancer, and in some embodiments, the personal care compositions contain no or substantially no any or all of fatty acid monoethanolamide, fatty acid diethanolamide, CMEA, CDEA, and lauryl diethanolamide. In some embodiments, the personal care compositions disclosed herein contain no or substantially no CMEA.

[0069] In some embodiments, the amount of at least one foaming agent in the personal care composition may be in the range of about 0% by weight to about 3% by weight, for example, about 0.1% by weight to about 3% by weight, about 0.2% by weight to about 2.8% by weight, about 0.5% by weight to about 2.5% by weight, about 0.8% by weight to about 2% by weight, about 1% by weight to about 1.5% by weight, or about 1% by weight, based on the total weight of the personal care composition.

[0070] In some embodiments, the personal care compositions disclosed herein may comprise at least one antimicrobial agent. Non-limiting examples of such antimicrobial agents include benzoic acid, benzoates, salicylic acid and salicylates, benzoic acid esters, sorbic acid esters, sorbates, para-hydroxybenzoates, alkyl lactates, citrates, alkyl malates and alkyl glycolates, and mixtures thereof. Based on the total weight of the personal care composition, the antimicrobial agent may be present in an amount ranging from about 0.1% by weight to about 1% by weight, including all amounts and subranges therebetween.

[0071] The personal care compositions disclosed herein may also contain a pH adjuster (also known as a pH modifier). Non-limiting examples of such pH adjusters include acetic acid, adipic acid, ascorbic acid, citric acid, dehydroacetic acid, isoascorbic acid, fumaric acid, glutaric acid, gluconic acid, hyaluronic acid, glycolic acid, lactic acid, malic acid, sorbic acid, succinic acid, tannic acid, tartaric acid, sulfuric acid, phosphoric acid, nitric acid, hydrochloric acid, aminosulfonic acid, carboxylic acid polymers, homopolymers or heteropolymers of α-hydroxycarboxylic acids (including polylactic acid and polylactic-glycolic acid), and mixtures of two or more of the aforementioned acids.

[0072] The pH of a personal care composition can be adjusted using a pH adjuster based on its intended end application. For example, for hand soap applications, the personal care composition may contain a pH adjuster in an amount that makes the pH of the personal care composition close to that of the skin (i.e., a pH of about 5 to 5.5). In other embodiments, for example, to impart conditioning to the skin, the personal care composition may have a pH higher than that of the skin. In some embodiments, a suitable pH is about 3.5 to about 5.5. In a non-limiting embodiment, the pH adjuster may be present in an amount ranging from about 0.1% by weight to about 10% by weight, including all amounts and subranges therebetween, based on the total weight of the personal care composition.

[0073] The personal care compositions disclosed herein may also contain one or more ionic additives as viscosity modifiers. The ionic additives may be salts, and may include any desired salt. Examples of salts include, but are not limited to, sodium chloride and magnesium sulfate.

[0074] In some embodiments, the personal care composition may contain a suitable antioxidant, i.e., a substance known to inhibit oxidation. Suitable antioxidants according to this disclosure include, but are not limited to, butylated hydroxytoluene, ascorbic acid, sodium ascorbate, calcium ascorbate, ascorbyl palmitate, butylated hydroxyanisole, 2,4,5-trihydroxybenzophenone, 4-hydroxymethyl-2,6-di-tert-butylphenol, isoascorbic acid, guaiac gum, propyl gallate, thiodipropionic acid, dilauryl thiodipropionate, tert-butylhydroquinone, and tocopherols such as vitamin E, including pharmaceutically acceptable salts and esters of these compounds, such as butylated hydroxytoluene, butylated hydroxyanisole, propyl gallate, ascorbic acid, their pharmaceutically acceptable salts or esters, or mixtures thereof; for example, butylated hydroxytoluene. When the personal care compositions disclosed herein contain at least one antioxidant, the total amount of antioxidant present, based on the total weight of the personal care composition, may be from about 0.001% by weight to about 0.5% by weight, for example, from about 0.05% by weight to about 0.5% by weight, or about 0.1% by weight.

[0075] Further embodiments provide a personal care composition comprising a chelating agent that forms a complex with a metal cation that does not cross the lipid bilayer. Examples of suitable chelating agents may include trisodium ethylenediaminedisuccinate, ethylenediaminetetraacetic acid (EDTA), ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid (EGTA), and tetrapotassium salt of 8-amino-2-[(2-amino-5-methylphenoxy)methyl]-6-methoxyquinoline-N5N,N′,N′-tetraacetic acid (QUIN-2). When the personal care composition comprises at least one chelating agent, the total amount of the chelating agent present may range from about 0.005% by weight to about 2% by weight, depending on the specific chelating agent and formulation chosen. For example, in some embodiments, the composition may comprise about 0.05% by weight to about 0.2% by weight of trisodium ethylenediaminedisuccinate.

[0076] In some embodiments, the personal care composition may contain at least one fragrance ingredient. Fragrances that can be used in personal care compositions include a wide variety of natural and synthetic chemical ingredients, including but not limited to aldehydes, ketones, esters, etc. Various natural extracts and essences, such as essential oils, are also included. At least one fragrance agent may be selected in a non-limiting manner from the following fragrance agents and essential oils: ambrette, angelica, fennel, amygdalin, bay leaf, bergamot, balsam, basil, bois-de-rose, juniper, cajiput, camphor, ylang-ylang, Javanese cassia, clary sage, curry, calamus, costus, carrot, cedarwood, cedarwood, cinnamon, Javanese lemongrass, clove, cyperiol, chamomile blue, Roman chamomile, davana, dill, elemi, eucalyptus, eucalyptus globule, frankincense, geranium, ginger, ginger flower. Lily, Galangal, Gurjam, Grapefruit, Jasmine, Juniper Berry, Juniper, Kapoorkatcheri, Lavender, Lemon, Lemongrass, Lemon Melissa, Lime, Bay Spearmint, Lemon Balsam, Litsea cubeba, Lemon Mint, Menthol Piperrata, Shivalik Mint, Citrus, Marjoram, Mint, Musk, Myrtle, Nar Kachur, Orange Blossom, Melaleuca Chinensis, Orange, Sweet Orange, Oregano, Bitter Patchouli, Patchouli, Petit Grain, Peppermint, Pine, Palmarosa, Pimentoberry, Rose, Rosewood, Rosemary Marry, rosemary, sandalwood, spearmint, sugandhmantri, nard, tarragon, orange, tea tree, thyme, forsythia, tomar (zanthozylum), tagettues, vetiver, valerian, holly, wormwood (fragrant white pearl), ylang, zadoeria, and any combination thereof.

[0077] When present, at least one fragrance agent may be present in the personal care composition in any amount sufficient to impart the desired properties (including fragrance and viscosity) to the personal care composition. In some embodiments, based on the total weight of the personal care composition, at least one fragrance agent may be present in the personal care composition in an amount ranging from about 0.1 wt% to about 1.3 wt%, for example, from about 0.2 wt% to about 1.2 wt%, from about 0.3 wt% to about 1 wt%, or from about 0.4 wt% to about 0.9 wt%. In some embodiments, based on the total weight of the personal care composition, at least one fragrance agent is present in the personal care composition in the following amounts: about 0.1 wt%, about 0.2 wt%, about 0.3 wt%, about 0.4 wt%, about 0.5 wt%, about 0.6 wt%, about 0.7 wt%, about 0.8 wt%, about 0.9 wt%, about 1.0 wt%, about 1.1 wt%, about 1.2 wt%, or about 1.3 wt%.

[0078] The personal care composition may also contain at least one natural preservative, which may be one or more extracts of: fennel, blackcurrant, cinnamon or cinnamon oil, geranium or geranium oil, ginger or ginger oil, Indian ginseng root, lavender, lemongrass, Magnolia acnibio, maritime pine, peppermint (Mentha piperita), olive leaf, oregano, peppermint, elderberry, rosemary, tea tree, thyme, and grapefruit. In some embodiments, the amount of at least one natural preservative is in the range of about 0.1% by weight to about 5% by weight, based on the total weight of the personal care composition.

[0079] In some embodiments, the personal care compositions disclosed herein further comprise an antimicrobial agent. Non-limiting examples of suitable antimicrobial agents according to this disclosure may include alcohols, aldehydes, antimicrobial acids or salts thereof, carboxylic acid esters, amides, phenols, phenol derivatives, biphenyls, diphenylalkanes, urea derivatives, oxyacetals, nitroacetals and formaldehydes, benzylamidinium, isothiazazoles, and their derivatives. Derivatives such as isothiazolinides and isothiazolinones, phthalimide derivatives, pyridine derivatives, antimicrobial surfactants, guanidines, antimicrobial amphoteric compounds, quinolines, 1,2-dibromo-2,4-dicyanobutane, iodo-2-propynyl-butylcarbamate, iodine, iodine carriers, and peroxides are also considered. Preferred antimicrobial agents are selected from the group consisting of: ethanol, n-propanol, isopropanol, 1,3-butanediol, phenoxyethanol, 1,2-propanediol, glycerol, undecanoic acid, citric acid, lactic acid, benzoic acid, salicylic acid, thymol, 2-benzyl-4-chlorophenol, 2,2′-methylenebis(6-bromo-4-chlorophenol), 2,4,4′-trichloro-2′-hydroxydiphenyl ether, N-(4-chlorophenyl)-N-(3,4-dichlorophenyl)urea, N,N′-(1,10-decadiylbis-1-pyridyl-4-ylidene)bis(1-octylamino)dihydrochloride, N,N′-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanodiimide (N,N'-bis)

[0080] (4-Chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecandiimidamide), antimicrobial quaternary surfactants, and guanidine. In addition, antimicrobial-effective essential oils can be used, which can also provide fragrance to personal care compositions.

[0081] The personal care compositions disclosed herein can be cleaning products. Non-limiting examples of the personal care compositions disclosed herein may include liquid hand soaps, facial cleansers, body gels, shampoos, conditioners, shower gels, or skin cleansers. In some embodiments, the personal care composition is a body gel, body gel, or skin cleanser.

[0082] Personal care compositions can be formulated to a viscosity of approximately 3,000 cP to approximately 15,000 cP in undiluted form using a Brookfield DV2T viscometer with a No. 5 spindle at 20 RPM and 25°C. In some cases, the personal care compositions are used with Brookfield... The viscometer, using a No. 5 spindle at 20 RPM and 25°C, produces viscosities of approximately 3,000 cP to approximately 15,000 cP, approximately 3,000 cP to approximately 12,000 cP, approximately 3,000 cP to approximately 10,000 cP, approximately 3,000 cP to approximately 8,000 cP, approximately 3,000 cP to approximately 7,000 cP, approximately 3,000 cP to approximately 6,000 cP; approximately 3,500 cP to approximately 15,000 cP, approximately 3,500 cP to approximately 12,000 cP, approximately 3,500 cP to approximately 10,000 cP, approximately 3,500 cP to approximately 8,000 cP, approximately 3,500 cP to approximately 7,000 cP, and approximately 3,500 cP to approximately 6,000 cP. About 4,000 cP to about 15,000 cP, about 4,000 cP to about 12,000 cP, about 4,000 cP to about 10,000 cP, about 4,000 cP to about 8,000 cP, about 4,000 cP to about 7,000 cP, about 4,000 cP to about 6,000 cP; about 4,500 cP to about 15,000 cP, about 4,500 cP to about 12,000 cP, about 4,500 cP to about 10,000 cP, about 4,500 cP to about 8,000 cP, about 4,500 cP to about 7,000 cP, about 4,500 cP to about 6,000 cP, about 4,500 cP to about 5,000 cP, or any range or subrange thereof.

[0083] Personal care compositions can be provided in containers, such as resealable bottles configured for incremental dispensing of the personal care composition when desired for use, such as during bathing.

[0084] This document also discloses methods for cleansing skin and / or hair, including applying the personal care composition disclosed herein to the skin and / or hair; washing; and optionally rinsing with water. In addition to cleansing, the personal care compositions disclosed herein can also be used to moisturize the skin and / or hair. For example, in some embodiments, the personal care composition may be applied to the skin and / or hair. If the personal care composition is a wash-off composition, the composition is rinsed off after application, for example, with water. In some embodiments, the personal care composition may be retained for any desired amount of time. The personal care composition may be in the form of shower gel, body gel, hand soap, shampoo, conditioner, skin cleanser, sunscreen, bubble bath, etc.

[0085] This disclosure also provides a method for manufacturing a personal care product comprising the personal care composition disclosed herein. The method includes: blending a surfactant with a personal care ingredient comprising at least one preservative to form a personal care composition. Subsequently, the method includes adding a predetermined volume of the personal care composition to a container to form a personal care product.

[0086] Example

[0087] The embodiments and other implementations described herein are exemplary and are not intended to limit the full scope of the compositions and methods described herein. Equivalent changes, modifications, and variations can be made to the specific embodiments, materials, compositions, and methods within the scope of this disclosure, with substantially similar results.

[0088] Example 1 - Prototype Formulation and Stability Assessment

[0089] Five initial prototype formulations were prepared as shown in Table 1 below. It should be noted that none of the formulations contained sulfates or betaine.

[0090] Table 1 - Preparations without sulfates or betaine

[0091]

[0092] As shown in Table 1, Prototype 1 contained no preservatives and the pH was lowered to approximately 4.0 using citric acid. Prototype 1 had an initial viscosity of approximately 3840 cps, which was considered acceptable for a personal care composition (e.g., shower gel). However, Prototype 1 failed the micro-robustness test, exhibiting a micro-robustness index (MRI) below 1 (0.64). In Prototype 2, SMCT was increased to 12%, and 0.25% sodium benzoate was added as a preservative. Prototype 2 had a relatively low MRI of 0.76. In Prototype 3, lactic acid was added as a preservative to improve micro-robustness, and Prototype 3 passed the micro-robustness test with an MRI of 1.29; however, Prototype 3 had a low initial viscosity (2390 cps). In Prototype 4, SMCT and cocoamphoacetate were adjusted to approximately 13% and 19%, respectively, and 2% lactic acid was added as a preservative. Prototype 4 passed the micro-robustness test with an MRI of 1.2. In Prototype 5, SMCT and cocoamphoacetate were adjusted to approximately 13% and 19%, respectively, and 0.74% lactic acid and 2.1% sodium lactate were added as preservatives. Prototype 5 also passed the micro-robustness test, with an MRI score of 1.31. Prototype 4 was selected for further evaluation.

[0093] Example 2 - Viscosity Assessment

[0094] As shown in Table 2 below, the prototype 4 prepared in Example 1 was further adjusted, and the viscosity of prototypes 4.1, 4.2 and 4.3 was evaluated.

[0095] Table 2 - Formulations for assessing viscosity

[0096]

[0097] The appearance, viscosity, and pH of prototype 4.1 were measured over time and at temperature, and the results are shown in Table 3 below.

[0098] Table 3 - pH and viscosity of prototype 4.1

[0099]

[0100] Because the fragrance-free base of prototype 4.1 performed well in viscosity tests, fragrances were added to prototypes 4.2 and 4.3. Since the initial viscosity of prototype 4.1 was only 4140 cps, the amounts of SMCT and amphoteric acetate added to prototypes 4.2 and 4.3 were increased to 13% and 19%, respectively. It was observed that adding 0.9% fragrance to prototype 4.2 resulted in a sharp decrease in initial viscosity to 330 cps. Therefore, the fragrance dosage was reduced to 0.4% in prototype 4.3, with an initial viscosity of 3370 cps. These results indicate that fragrances may have a significant impact on the viscosity of sulfate-free and betaine-free personal care compositions.

[0101] Based on the formulation of prototype 4.2, other prototypes were prepared using different fragrances, as shown in Table 4 below.

[0102] Table 4 - Other prototypes and viscosities with fragrances

[0103] Fragrance Initial viscosity 0.9% floral fragrance 860cps 0.95% coconut flavor 1000cps 0.8% Pastel fragrance 630cps

[0104] The results confirmed previous observations that fragrances have a significant effect on the viscosity of sulfate-free and betaine-free personal care compositions.

[0105] Example 3 - Performance Evaluation

[0106] A panel of experts was convened to evaluate the performance of the sulfate-free, betaine-free composition (prototype 6) compared to a control composition containing a surfactant blend of cocamidopropyl betaine, SLES, and cocoyl glucoside. Both formulations are shown in Table 5 below.

[0107] Table 5 - Control formulation and sulfate-free and betaine-free prototype 6

[0108]

[0109] Dynamic Foam Analysis (DFA) was used to evaluate the foam volume, foaming rate, bubble density, and bubble density of the formulation. Figure 1 The foaming curves of both the control and prototype 6 are shown, displaying the foam volume over time. Figure 2 The maximum foam volume achieved by the control (84.8 mL) is shown compared to prototype 6 (110.2). Figure 2 As shown, prototype 6 achieves a significantly larger foam volume. Figure 1 and Figure 2 Together, they demonstrated that, compared to the control, the sulfate-free and betaine-free shower gel provided a larger foam volume and also had improved foam stability. Figure 3 The foaming rate of the formulation is shown, measured in mm / s. Figure 3 As shown, prototype 6 has a significantly faster foaming rate (1.7 mm / s) compared to the control (0.9 mm / s).

[0110] DFA also provides both bubble counting and bubble size measurement. For example... Figure 4 As shown, the bubble count of prototype 6 is 203.0 bubbles / mm. 3 The control formulation had a bubble count of 225.5 bubbles / mm. 3 .like Figure 5 As shown, the average initial bubble size measured for prototype 6 was 36.7 μm, while that for the control formulation was 35.0 μm.

[0111] In addition, a panel of experts (10) trained in descriptive analysis of skin sensation assessed sensory / skin sensation through evaluation, with each sample evaluated twice. Attributes were rated using an intensity scale from 1 to 100, where 0 represents none and 100 represents very strong. Overall, the panel determined that Prototype 6 and the control had similar performance in terms of foam volume and moisturizing properties, with Prototype 6 producing a thicker foam. The results are shown in Table 6 below.

[0112] Table 6 - Summary of Performance Evaluation

[0113]

[0114] The expert panel provided feedback on the control and prototype 6 formulations. Specifically, according to the panel, the control had low to moderate amounts of loose foam, a slight floral scent, and low to moderate amounts of residue, characterized as initially waxy and greasy, then becoming a greasy, waxy residue topped with powder. The panel also characterized prototype 6 as providing low to moderate amounts of thick, creamy foam with a fresh floral scent. After application, prototype 6 had low to moderate amounts of residue, characterized as initially waxy, then becoming a waxy residue topped with powder.

Claims

1. A personal care composition comprising: Surfactant blends containing anionic and amphoteric surfactants; and At least one preservative, The personal care composition described herein is free of sulfates and betaine.

2. The personal care composition according to claim 1, wherein the anionic surfactant is an acyl taurate, preferably sodium methyl cocoyl taurate.

3. The personal care composition according to claim 1, wherein the amphoteric surfactant is an amphoteric acetate.

4. The personal care composition according to any one of the preceding claims, wherein the amphoteric surfactant is selected from sodium cocoamphoacetate or sodium lauroylamphoacetate, preferably sodium cocoamphoacetate.

5. The personal care composition according to any one of the preceding claims, wherein the anionic surfactant is present in the personal care composition in an amount ranging from about 1% to about 10% by weight, for example from about 1% to about 5% by weight or from about 3.5% to about 4% by weight, based on the total weight of the personal care composition.

6. The personal care composition according to any one of the preceding claims, wherein the amphoteric surfactant is present in the personal care composition in an amount ranging from about 1% to about 10% by weight, for example from about 4% to about 7% by weight or from about 5% to about 6% by weight, based on the total weight of the personal care composition.

7. The personal care composition according to any one of the preceding claims, wherein the at least one preservative is selected from lactic acid, sodium benzoate, sodium lactate and combinations thereof, preferably lactic acid.

8. The personal care composition according to any one of the preceding claims, wherein the at least one preservative is present in the personal care composition in an amount ranging from about 1% to about 5% by weight, for example, from about 1% to about 2% by weight, relative to the total weight of the personal care composition.

9. The personal care composition according to any one of the preceding claims further comprises at least one liquid carrier, optionally wherein the at least one liquid carrier is water.

10. The personal care composition according to any one of the preceding claims further comprises at least one fragrance.

11. The personal care composition of claim 10, wherein the at least one fragrance is present in an amount of about 0.3% to about 1.3% by weight, for example, about 0.4% to about 0.9% by weight, based on the total weight of the personal care composition.

12. The personal care composition according to any one of the preceding claims, wherein the viscosity of the personal care composition is in the range of about 3,000 cps to about 6,000 cps, for example, about 4,000 cps to about 5,500 cps or about 4,500 cps to about 5,250 cps.

13. The personal care composition according to any one of the preceding claims, wherein the surfactant blend comprises an acyl taurate and an amphoteric acetate, preferably SMCT and sodium cocoamphoacetate.

14. The personal care composition according to any one of the preceding claims, wherein the amphoteric surfactant and the anionic surfactant are present in a weight ratio of about 1:1 to about 5:1, for example, about 1:1 to about 2:1, about 1.4:1, about 1.5:1 or about 1.46:

1.

15. The personal care composition according to any one of the preceding claims, wherein the personal care composition is a bath soap, bath gel, shampoo, conditioner, body wash or skin cleanser, preferably a body wash.

16. The personal care composition according to any one of the preceding claims, wherein the personal care composition further comprises at least one foaming agent.

17. The personal care composition according to any one of the preceding claims, wherein the micro robustness index of the personal care composition is at least about 0.85, for example at least about 1.0, at least about 1.2, at least about 1.3, or at least about 1.

4.

18. The personal care composition according to any one of the preceding claims, wherein the pH of the personal care composition is in the range of about 4 to about 5.

19. A method of manufacturing a personal care product, the method comprising: A surfactant blend containing anionic surfactants and amphoteric surfactants is blended with at least one preservative to form a personal care composition according to any one of claims 1 to 18. as well as A predetermined volume of the personal care composition is added to a container to form the personal care product.

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