Application of rice RNA adenine methyltransferase gene in regulating plant resistance to virus

By regulating the expression of the RNA adenine methyltransferase gene EDM2L in rice, the problem of RSV resistance in rice was solved, achieving effective resistance to RSV and improving the growth and health status of rice.

CN122303292APending Publication Date: 2026-06-30INST OF ZOOLOGY CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF ZOOLOGY CHINESE ACAD OF SCI
Filing Date
2026-01-09
Publication Date
2026-06-30

AI Technical Summary

Technical Problem

Existing technologies are insufficient to effectively regulate rice resistance to rice stripe virus (RSV), leading to severe stunted growth or death of rice plants after infection, affecting yield and quality.

Method used

By knocking out or overexpressing the RNA adenine methyltransferase gene EDM2L in rice, the antiviral ability of rice can be regulated, reducing or enhancing its resistance to RSV.

Benefits of technology

It significantly modulates rice resistance to RSV, weakens or enhances its resistance to RSV, improves rice growth, and reduces virus accumulation.

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Abstract

This invention belongs to the field of plant biocontrol. Specifically, this invention provides the application of the rice RNA adenine methyltransferase EDM2L gene in regulating plant antiviral resistance. This was achieved by comparing rice plants inoculated with RSV virus. edm2l Knockout mutants and edm2l' Analysis of methyltransferase catalytic activity mutants and ZH11 wild plants revealed that knockout edm2l Downregulation of EDM2L expression significantly weakens rice's resistance to RSV, indicating that this gene has an anti-RSV function. This invention provides a new target gene locus for cultivating crops with enhanced virus resistance using genetic engineering techniques, and has significant implications and broad application prospects in regulating plant resistance and disease-resistant breeding.
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