Apostichopus japonicus pathogen shewanella antagonistic bacterium and application thereof

By isolating and screening Japanese seaweed bacteria from the intestines of sea cucumbers as antagonistic bacteria, a microecological preparation was prepared for use in sea cucumbers. This solved the problem of relying on antibiotics for the prevention and treatment of sea cucumber skin rot syndrome in existing technologies, and achieved a safe and efficient pathogen antagonistic effect.

CN122344535APending Publication Date: 2026-07-07DALIAN OCEAN UNIV
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Patent Information

Application Number
CN202610743359.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-27
Publication Date
2026-07-07

AI Technical Summary

Technical Problem

Current technologies for the prevention and treatment of sea cucumber skin rot syndrome rely on antibiotics and lack safe and effective microecological agents, which affects the safety of aquatic organisms and the balance of the ecosystem.

Method used

A microecological preparation for preventing and treating sea cucumber skin rot syndrome is provided, specifically Gilvimarinus japonicus, an antagonistic bacterium against the pathogen Shewanella spp., which is administered via intraperitoneal injection or immersion. It significantly antagonizes the pathogen Shewanella B9.

Benefits of technology

This antagonistic bacterium is safe and non-toxic to sea cucumbers, and can significantly inhibit the pathogen of skin rot syndrome, improve the survival rate of sea cucumbers exposed to pathogens, and provide a safe and efficient prevention and control measure.

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Abstract

The invention discloses apostichopus japonicus pathogenic shewanella antagonistic bacteria and application thereof, and belongs to the technical field of aquatic microorganisms. The antagonistic bacterium is separated from healthy apostichopus japonicus intestinal tracts, is identified as Gilvimarinus japonicus, has no beta-hemolysis characteristic, is safe and non-toxic to apostichopus japonicus, and can be used for remarkably antagonizing pathogenic bacteria shewanella of skin ulcer syndrome of apostichopus japonicus. The invention also discloses an application of the antagonistic bacterium, the antagonistic bacterium can be prepared into an aquatic microecological preparation for preventing and treating the skin ulceration syndrome of the apostichopus japonicus, the aquatic microecological preparation is applied in an intraperitoneal injection or immersion bath mode, the survival rate of the apostichopus japonicus under the exposure of pathogenic bacteria can be remarkably improved, and the strain has relatively strong saline-alkaline resistance, has tolerance to various antibiotics and chemical drugs, and has a good application prospect in preventing and treating the skin ulceration syndrome of the apostichopus japonicus. The method is simple in process and high in environmental adaptability, can replace traditional antibiotics to be applied to culture of apostichopus japonicus, effectively solves the problems of food safety and environmental pollution caused by abuse of antibiotics, and has a good industrial application prospect.
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