Transcatheter intervention therapy right heart valve simulator

Abstract

This invention relates to a simulator for transcatheter interventional treatment of right ventricular valves, comprising a model mounting housing with multiple simulated liquid inlet channels and multiple simulated liquid outlet channels disposed in the left and right side walls of the housing; the multiple liquid inlet channels are connected to a shunt device via pipes, the shunt device is connected to a heating device via pipes, the heating device is connected to a simulated liquid storage device via pipes, the simulated liquid storage device is connected to a manifold via pipes, the manifold is connected to the simulated liquid outlet channels via pipes, and a liquid pump is also disposed between the simulated liquid storage device and the heating device; the simulator for transcatheter interventional treatment of right ventricular valves can simulate the flow of blood in a pulsating conduit model, thereby more realistically simulating the process of transcatheter interventional treatment of right ventricular valves, allowing doctors to simulate surgery in a model that is closer to a real environment before performing actual surgery, thereby improving the success rate of the surgery.

Description

Technical Field

[0001] This invention belongs to the technical field of pulsating conduit models, specifically relating to a catheter-based simulator for right heart valve intervention. Background Technology

[0002] Right ventricular valvular disease severely impacts patient survival. Transcatheter interventional techniques are renowned for their safety and effectiveness, and have demonstrated promising results in treating right ventricular valvular disease. However, it remains a relatively new and developing technology.

[0003] Transcatheter implantation of an artificial heart valve is a complex cardiac procedure that requires rigorous extracorporeal hydrodynamic testing before surgery to ensure safety and effectiveness during the procedure. These tests need to simulate various scenarios during heart valve reoperation, including closure and opening, expansion and contraction.

[0004] The technical details still require in-depth study and widespread application. Currently, simulation can only be performed using 3D-printed models of the patient's right heart. However, within the heart chambers and blood vessels, the operation and positioning of instruments and guidewires under the influence of blood flow require greater precision to ensure accurate instrument placement. Summary of the Invention

[0005] This addresses the issue that existing pulsatile conduit models cannot simulate the impact of blood vessels on transcatheter interventional treatment of right heart valves.

[0006] This invention provides a catheter-based right heart valve intervention simulator, comprising a model body disposed within a model mounting housing. Multiple simulated liquid inlet channels are provided on one side wall of the model mounting housing, and multiple simulated liquid outlet channels are provided on the other side wall. The multiple liquid inlet channels are connected to a shunt device via pipes. The shunt device is connected to a heating device via pipes. The heating device is connected to a simulated liquid storage device via pipes. The simulated liquid storage device is connected to a manifold via pipes. The manifold is connected to the simulated liquid outlet channels via pipes. A liquid pump is also provided between the simulated liquid storage device and the heating device.

[0007] Furthermore, the model mounting housing is symmetrically provided with module mounting shafts inside, and model mounting seats are provided on the left and right sides of the model body. The module mounting shafts are rotatably connected to the model mounting seats.

[0008] Furthermore, each of the multiple simulated liquid inlet channels is equipped with an inlet control valve; and each of the multiple simulated liquid inlet channels is equipped with an inlet retaining ring at both ends.

[0009] Furthermore, each of the multiple simulated liquid outlet channels is equipped with an outlet control valve; and each of the multiple simulated liquid outlet channels is equipped with an outlet retaining ring at both ends.

[0010] Furthermore, a T-junction is provided in the pipeline between the diversion device and the heating device, and the T-junction is connected to the simulated liquid storage device through the pipeline.

[0011] Furthermore, the aforementioned transcatheter interventional right heart valve simulator also includes a control system. The control system includes multiple data acquisition sensors, a signal amplification module, an AD conversion module, and a control module. The multiple data acquisition sensors are electrically connected to the signal amplification module, the signal amplification module is electrically connected to the AD conversion module, the AD conversion module is electrically connected to the control module, and the control module is electrically connected to the liquid pump, the heating device, and various pipeline valves.

[0012] Furthermore, the plurality of data acquisition sensors include a liquid pressure sensor, a liquid temperature sensor, a liquid flow rate sensor, and a liquid flow sensor.

[0013] Furthermore, the signal amplification module circuit includes resistors R1 to R7, capacitors C1 and C2, amplifiers U1A and U1B, transistor Q1, and LED1. One end of resistor R1 is electrically connected to the positive terminal of the power supply, and the other end of resistor R1 is electrically connected to the positive input terminal of amplifier U1B. The other end of resistor R1 is also electrically connected to one end of resistor R2, and the other end of resistor R2 is electrically connected to the negative input terminal of amplifier U1A. The other end of resistor R2 is electrically connected to ground via resistor R3, and also to ground via capacitor C1. The signal input terminal Vin is connected to the positive input terminal of amplifier U1A. The signal input terminal Vin is also electrically connected to the negative input terminal of amplifier U1B. The output terminal of amplifier U1A is electrically connected to the output terminal of amplifier U1B. The output terminal of amplifier U1B is electrically connected to the base of transistor Q1 through resistor R5. The emitter of transistor Q1 is electrically connected to the ground terminal. Resistor R6 is placed between the base and emitter of transistor Q1. The positive terminal of the power supply is electrically connected to the positive terminal of LED1 through resistor R7. The negative terminal of LED1 is electrically connected to the collector of transistor Q1. The collector of transistor Q1 is the signal input terminal Vout. The positive terminal of the power supply is electrically connected to the output terminal of amplifier U1B through resistor R4.

[0014] Furthermore, the model number of the AD conversion module is ICL7109.

[0015] Furthermore, the control module is model STM32F03C8T6.

[0016] The beneficial effects of this invention: The right heart valve simulator provided by this invention can simulate the flow of blood in a pulsatile conduit model, thereby more realistically simulating the process of right heart valve intervention through a catheter. This allows doctors to simulate the surgery in a model that is closer to the real environment before performing the actual surgery, thereby improving the success rate of the surgery.

[0017] The present invention will be further described in detail below with reference to the embodiments. Attached Figure Description

[0018] Figure 1 A schematic diagram of the structure for installing the shell on the model.

[0019] Figure 2 This is a schematic diagram of the installation structure of the main body of the model.

[0020] Figure 3 This is a schematic diagram of the simulated fluid circulation process in a catheter-based right heart valve intervention simulator.

[0021] Figure 4 A three-dimensional structural diagram of the housing for the model.

[0022] Figure 5 This is a schematic diagram of the control system.

[0023] Figure 6 This is a circuit diagram of the amplification module.

[0024] Figure 7 Schematic diagram of power supply circuit Figure 1 .

[0025] Figure 8 Schematic diagram of power supply circuit Figure 2 .

[0026] Figure 9 This is a circuit diagram of an AD conversion module.

[0027] Figure 10 This is a circuit diagram of the control module.

[0028] Figure 11 This is a circuit diagram of a relay.

[0029] In the diagram: 1. Model body; 2. Model mounting shell; 3. Module mounting shaft; 4. Model mounting base; 5. Simulated liquid inlet channel; 6. Simulated liquid outlet channel; 7. Inlet control valve; 8. Inlet snap ring; 9. Outlet control valve; 10. Outlet snap ring; 11. Diverter; 12. Heating device; 13. Simulated liquid storage device; 14. Manifold; 15. Liquid pump; 16. T-junction. Detailed Implementation

[0030] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the specific implementation methods, structural features and effects of the present invention are described in detail below with reference to the accompanying drawings and embodiments.

[0031] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0032] In the description of this invention, it should be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "aligned", "overlapping", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0033] The terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature; in the description of this invention, unless otherwise stated, "a plurality of" means two or more.

[0034] Example 1

[0035] To address the issue that existing pulsatile conduit models cannot simulate the impact of blood vessels on transcatheter interventional treatment of right heart valves.

[0036] This invention provides a method such as Figures 1 to 11The transcatheter interventional right heart valve simulator shown includes a model body 1, which is a heart model made using existing 3D printing technology based on the patient's heart. The model body 1 has a fluid pathway simulating blood flow, allowing for the simulation of blood flow within the heart. The model body 1 is housed within a model mounting housing 2. Multiple simulated fluid inlet channels 5 are provided on one side wall of the model mounting housing 2, and multiple simulated fluid outlet channels 6 are provided on the other side wall. The multiple fluid inlet channels 5 are connected to a shunt device 11 via pipes. The shunt device 11 is connected to a heating device 12 via pipes. The heating device 12 is connected to a simulated fluid storage device 13 via pipes. The simulated fluid storage device 13 is connected to a manifold device 14 via pipes. The manifold device 14 is connected to the simulated fluid outlet channels 6 via pipes. A fluid pump 15 is also provided between the simulated fluid storage device 13 and the heating device 12.

[0037] Furthermore, the model mounting housing 2 is symmetrically provided with module mounting shafts 3 inside, and model mounting seats 4 are provided on the left and right sides of the model body 1. The module mounting shafts 3 are rotatably connected to the model mounting seats 4.

[0038] Furthermore, each of the plurality of simulated liquid inlet channels 5 is equipped with an inlet control valve 7; and each of the plurality of simulated liquid inlet channels 5 is equipped with an inlet convex retaining ring 8 at both ends.

[0039] Furthermore, each of the plurality of simulated liquid outlet channels 6 is equipped with an outlet control valve 9; and each of the plurality of simulated liquid outlet channels 6 is equipped with an outlet retaining ring 10 at both ends.

[0040] Furthermore, a three-way pipe 16 is provided in the pipeline between the diversion device 11 and the heating device 12, and the three-way pipe 16 is connected to the simulated liquid storage device 13 through the pipeline.

[0041] Furthermore, such as Figure 5 As shown, the transcatheter right ventricular valve simulator further includes a control system. The control system includes multiple data acquisition sensors, a signal amplification module, an AD conversion module, and a control module. The multiple data acquisition sensors are electrically connected to the signal amplification module, the signal amplification module is electrically connected to the AD conversion module, the AD conversion module is electrically connected to the control module, and the control module is electrically connected to the fluid pump transcatheter right ventricular valve simulator 15, the heating device transcatheter right ventricular valve simulator 12, and various pipeline valves.

[0042] Furthermore, the plurality of data acquisition sensors include a liquid pressure sensor, a liquid temperature sensor, a liquid flow rate sensor, and a liquid flow sensor; each sensor can be flexibly configured according to the needs of liquid monitoring, for example, Figure 1 As shown, sensors are installed in the liquid inlet channel 5 and the simulated liquid outlet channel 6 of the model mounting housing 2 to monitor the pressure, flow rate, temperature, etc. of the simulated liquid entering and flowing into the model, so as to make real-time adjustments.

[0043] Furthermore, such as Figure 6 As shown, the signal amplification module circuit includes resistors R1 to R7, capacitors C1 and C2, amplifiers U1A and U1B, transistor Q1, and LED1. One end of resistor R1 is electrically connected to the positive terminal of the power supply, and the other end of resistor R1 is electrically connected to the positive input terminal of amplifier U1B. The other end of resistor R1 is also electrically connected to one end of resistor R2. The other end of resistor R2 is electrically connected to the negative input terminal of amplifier U1A. The other end of resistor R2 is electrically connected to ground via resistor R3 and capacitor C1. The signal input terminal Vin is connected to the positive input terminal of amplifier U1A. The signal input terminal Vin is electrically connected to the negative input terminal of amplifier U1B. The output terminal of amplifier U1A is electrically connected to the output terminal of amplifier U1B. The output terminal of amplifier U1B is electrically connected to the base of transistor Q1 through resistor R5. The emitter of transistor Q1 is electrically connected to ground. Resistor R6 is placed between the base and emitter of transistor Q1. The positive terminal of the power supply is electrically connected to the positive terminal of LED1 through resistor R7. The negative terminal of LED1 is electrically connected to the collector of transistor Q1. The collector of transistor Q1 is the signal input terminal Vout. The positive terminal of the power supply is electrically connected to the output terminal of amplifier U1B through resistor R4.

[0044] Furthermore, such as Figure 7 , Figure 8 The diagram shown is a schematic of the power module circuit. Figure 6 The power supply circuit shown can convert a 12V or 24V DC power supply to a 5V DC power supply. Figure 7 The power supply circuit shown can convert 5V DC power to 3.3V DC power, thus meeting the power requirements of various devices.

[0045] Furthermore, such as Figure 9 The diagram shown is a circuit diagram of an AD conversion module, the model of which is ICL7109.

[0046] Furthermore, such as Figure 10 The diagram shown is a circuit diagram of the control module, which is an STM32F03C8T6.

[0047] Furthermore, the diversion device 11 includes a main body, which is a hollow cuboid. A liquid inlet is provided on one side of the main body, and multiple liquid outlets are provided on the other side of the main body, so that one liquid can be diverted into multiple streams.

[0048] Furthermore, the structure of the confluence device 14 is exactly the opposite of that of the diversion device 11. The confluence device 14 also includes a hollow cuboid body with multiple liquid inlets on one side and a liquid outlet on the other side, so that multiple liquids can be combined into one liquid.

[0049] Furthermore, the simulated liquid storage device 13 is an existing liquid storage tank, which is equipped with an inlet, an outlet, and a tank opening for adding liquid.

[0050] Furthermore, the liquid pump 15 is a 24V miniature intelligent liquid pump, model BSP40160T.

[0051] Furthermore, the heating device 12 is a liquid electric heater that operates on 220V AC power, and its model is FJ-SX.

[0052] The aforementioned liquid pump 15 and heating device 12 both use a control module to control a relay. The relay controls the circuit switch of the liquid pump 15 or heating device 12, thereby controlling the operating status of the liquid pump 15 and heating device 12. Figure 11 The diagram shown is a schematic of a relay circuit.

[0053] In summary, this transcatheter right ventricular valve (VTVV) simulator can simulate blood flow in a pulsatile conduit model, thus more realistically simulating the VTVV treatment process. This allows doctors to simulate surgery in a model that closely resembles the real environment before performing actual surgery, thereby improving the success rate of the procedure.

[0054] The above description, in conjunction with specific preferred embodiments, provides a further detailed explanation of the present invention. It should not be construed that the specific implementation of the present invention is limited to these descriptions. For those skilled in the art, various simple deductions or substitutions can be made without departing from the concept of the present invention, and all such modifications and substitutions should be considered within the scope of protection of the present invention.

Claims

1. A catheter-based right heart valve simulator, comprising a model body (1), wherein the model body (1) is disposed within a model mounting shell (2), characterized in that: Multiple simulated liquid inlet channels (5) are provided on one side wall of the left and right side walls of the model mounting housing (2), and multiple simulated liquid outlet channels (6) are provided on the other side wall of the left and right side walls of the model mounting housing (2). The multiple liquid inlet channels (5) are connected to a diversion device (11) through pipelines. The diversion device (11) is connected to a heating device (12) through pipelines. The heating device (12) is connected to a simulated liquid storage device (13) through pipelines. The simulated liquid storage device (13) is connected to a confluence device (14) through pipelines. The confluence device (14) is connected to the simulated liquid outlet channels (6) through pipelines. A liquid pump (15) is also provided between the simulated liquid storage device (13) and the heating device (12).

2. The catheter-based right heart valve simulator as described in claim 1, characterized in that: The model mounting housing (2) is symmetrically provided with module mounting shafts (3), and the model body (1) is provided with model mounting seats (4) on the left and right sides. The module mounting shafts (3) are rotatably connected to the model mounting seats (4).

3. A catheter-based right heart valve simulator as described in claim 1, characterized in that: Each of the multiple simulated liquid inlet channels (5) is equipped with an inlet control valve (7); both ends of the multiple simulated liquid inlet channels (5) are equipped with inlet convex retaining rings (8).

4. A catheter-based right heart valve simulator as described in claim 1, characterized in that: Each of the multiple simulated liquid outlet channels (6) is equipped with an outlet control valve (9); both ends of the multiple simulated liquid outlet channels (6) are equipped with outlet convex retaining rings (10).

5. A catheter-based right heart valve simulator as described in claim 4, characterized in that: The pipeline between the diversion device (11) and the heating device (12) is also provided with a three-way pipe (16), which is connected to the simulated liquid storage device (13) through the pipeline.

6. A catheter-based right heart valve simulator as described in claim 4, characterized in that: It also includes a control system, which includes multiple data acquisition sensors, a signal amplification module, an AD conversion module, and a control module. The multiple data acquisition sensors are electrically connected to the signal amplification module, the signal amplification module is electrically connected to the AD conversion module, the AD conversion module is electrically connected to the control module, and the control module is electrically connected to the liquid pump (15), the heating device (12), and each pipeline valve.

7. A catheter-based right heart valve simulator as described in claim 6, characterized in that: The multiple data acquisition sensors include a liquid pressure sensor, a liquid temperature sensor, a liquid flow rate sensor, and a liquid flow sensor.

8. A catheter-based right heart valve simulator as described in claim 6, characterized in that: The signal amplification module circuit includes resistors R1 to R7, capacitors C1 and C2, amplifiers U1A and U1B, transistor Q1, and LED1. One end of resistor R1 is electrically connected to the positive terminal of the power supply, and the other end of resistor R1 is electrically connected to the positive input terminal of amplifier U1B. The other end of resistor R1 is also electrically connected to one end of resistor R2, and the other end of resistor R2 is electrically connected to the negative input terminal of amplifier U1A. The other end of resistor R2 is electrically connected to ground via resistor R3, and the other end of resistor R2 is also electrically connected to ground via capacitor C1. The signal input terminal Vin is electrically connected to the positive input terminal of amplifier U1A. The signal input terminal Vin is also electrically connected to the negative input terminal of amplifier U1B. The output terminal of amplifier U1A is electrically connected to the output terminal of amplifier U1B. The output terminal of amplifier U1B is electrically connected to the base of transistor Q1 through resistor R5. The emitter of transistor Q1 is electrically connected to ground. Resistor R6 is placed between the base and emitter of transistor Q1. The positive terminal of the power supply is electrically connected to the positive terminal of LED1 through resistor R7. The negative terminal of LED1 is electrically connected to the collector of transistor Q1. The collector of transistor Q1 is the signal input terminal Vout. The positive terminal of the power supply is electrically connected to the output terminal of amplifier U1B through resistor R4.

9. A catheter-based right heart valve simulator as described in claim 6, characterized in that: The model number of the AD conversion module is ICL7109.

10. A catheter-based right heart valve simulator as described in claim 6, characterized in that: The control module is model STM32F03C8T6.

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