Bacillus licheniformis-derived peptide-2 and its application in the prevention and control of root-knot nematode disease
By optimizing the nematicide-2 derived from Bacillus licheniformis, the problems of scarce root-knot nematode resistance resources and pollution from chemical control have been solved, providing an efficient and green control method and improving the control effect of root-knot nematodes.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HUAZHONG AGRI UNIV
- Filing Date
- 2026-05-19
- Publication Date
- 2026-07-17
AI Technical Summary
Root-knot nematodes cause serious damage and there is a lack of resistant resources. Chemical control leads to pesticide residues and resistance, making it difficult to meet the needs of green agriculture.
The nematicidal peptide Peptide-2 derived from Bacillus licheniformis was optimized using bioinformatics technology. By introducing methionine at the amino terminus and adjusting the number of positively charged residues and hydrophobic characteristics, it was optimized into a highly lethal nematicidal peptide.
Peptide-2 exhibits high lethality against root-knot nematodes and a high corrected mortality rate, meeting the needs of green agriculture for the development of biocontrol agents and the creation of new germplasm resources for root-knot nematode-resistant crops, thus overcoming the shortcomings of chemical control.
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Figure CN122404498A_ABST