Application of fg nat5 gene and its knockout mutant in the prevention and control of fusarium graminearum and wheat scab
By knocking out the FgNat5 gene in Fusarium graminearum, the ΔFgNat5 mutant was obtained, which significantly inhibited the growth of vegetative mycelia and pathogenicity of Fusarium graminearum. This solved the problems of drug resistance and environmental pollution in the control of wheat scab by chemical fungicides, and provided a green and ecological control solution.
Patent Information
- Application Number
- CN202610391050.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-03-27
- Publication Date
- 2026-07-17
AI Technical Summary
Existing chemical fungicides have problems such as increased resistance and environmental pollution in the control of wheat scab caused by Fusarium graminearum, and there is a lack of effective molecular target control strategies.
The FgNat5 gene was knocked out in wild-type strains of Fusarium graminearum to obtain the ΔFgNat5 mutant. The mutant was prepared and its application in Fusarium graminearum was verified by homologous recombination. It significantly inhibited the growth of vegetative mycelia and reduced pathogenicity.
After the FgNat5 gene was knocked out, the growth of vegetative mycelia of Fusarium graminearum was significantly slowed down, and its pathogenicity was greatly reduced, while the production of conidia was not affected, providing an effective method for green and ecological control of Fusarium graminearum and wheat scab.
Smart Images
Figure CN122405692A_ABST
Abstract
Citation Information
Patent Citations
Gene FgTEM1 for regulating pathogenicity of fusarium graminearum and application thereof
CN116064595A