Cell disruption probe for extracting adenophora stricta polysaccharide

By designing a cell crushing probe for sarcoside polysaccharide extraction, the sarcoside powder is stored in a bag and periodically rotated through the annular seat, the powder is in close contact with the ultrasonic probe, which solves the problem of the deposition of sarcoside powder affecting the extraction efficiency and achieves efficient polysaccharide extraction.

CN222658845UActive Publication Date: 2025-03-25QINGDAO AGRI UNIV HAIDU COLLEGE
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Patent Information

Application Number
CN202421249551.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-03
Publication Date
2025-03-25
Estimated Expiration
2034-06-03

AI Technical Summary

Technical Problem

In the prior art, sarcophagus powder is deposited in a solvent, resulting in the ultrasonic probe being unable to effectively exert an effect on it, affecting the extraction efficiency of sarcophagus polysaccharide components.

Method used

A cell crushing probe for extracting sarcoside polysaccharides is designed, and a bag is used to store the sarcoside powder, and the annular seat is periodically rotated to rotate the bag and the sarcoside powder inside it is ensured that the powder is in close contact with the ultrasonic probe.

Benefits of technology

Through uniform and stable ultrasonic action, the extraction efficiency of sarcoside polysaccharide components is improved, the subsequent filtration steps are avoided, and the operation is highly convenient.

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Abstract

The utility model relates to the technical field of traditional Chinese medicine treatment equipment, in particular to a cell disruption probe for extracting adenophora stricta polysaccharide. Comprising an ultrasonic probe body, a plurality of positioning columns II and an annular base, the positioning columns II and the annular base are arranged on the peripheral side of the ultrasonic probe body at equal angle intervals, a plurality of circular rings are fixedly connected and installed on the positioning columns II, the annular base is rotatably installed on the circular ring located at the top, and the circular rings located at the bottom are connected through a core base. The core seat is fixedly connected with a positioning column I at the bottom of the ultrasonic probe main body; a plurality of clamping edges are arranged on the inner side of the annular seat, bags are placed among the clamping edges, and adenophora stricta powder is placed in the bags; on the basis that the adenophora stricta powder is limited in the peripheral area of the ultrasonic probe, the accumulation position of the adenophora stricta powder is periodically adjusted, so that the ultrasonic probe exerts a uniform action effect on the adenophora stricta powder, and the extraction efficiency of adenophora stricta polysaccharide components is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of traditional Chinese medicine processing equipment, in particular to a cell breaking probe for extracting Adenophora adenophora polysaccharide. Background Art

[0002] The polysaccharide components in Adenophora adenophora can be extracted by a variety of methods, such as hot water reflux extraction, ultrasonic extraction, microwave extraction, alkali solution extraction, acid solution extraction and cellulase extraction, etc. Among them, the polysaccharide components in Adenophora adenophora are extracted by utilizing the cavitation effect, mechanical effect and thermal effect of ultrasound. Ultrasonic vibration can promote the rapid release of effective ingredients in the medicinal material into the solvent, thereby improving the extraction efficiency. The extraction operation can be carried out at a lower temperature, reducing the decomposition of heat-sensitive components, and is more suitable for extracting heat-unstable or easily hydrolyzed components.

[0003] In the prior art, the Adenophora radix is ​​usually crushed, sieved, and immersed in a solvent, and then the ultrasonic probe is inserted below the solvent surface. However, the Adenophora radix powder will settle in the solvent and maintain a certain distance from the ultrasonic probe, resulting in the ultrasonic probe being unable to effectively exert its effect on the Adenophora radix powder at the bottom of the container, thereby affecting the extraction efficiency of the Adenophora radix polysaccharide components. Therefore, the present application provides a cell disruption probe for extracting Adenophora radix polysaccharides. Utility Model Content

[0004] In order to solve the deficiencies in the above-mentioned prior art, the purpose of the utility model is to provide a cell disruption probe for extracting Adenophora radix polysaccharides. On the basis of confining the Adenophora radix powder to the area around the ultrasonic probe, the accumulation position of the Adenophora radix powder is periodically adjusted so that the ultrasonic probe can exert a uniform effect on the Adenophora radix powder, thereby improving the extraction efficiency of the Adenophora radix polysaccharide components.

[0005] The technical solution adopted by the utility model to solve its technical problems is:

[0006] Provided is a cell disruption probe for extracting Adenophora adenophora polysaccharide, comprising an ultrasonic probe body, a plurality of positioning columns II and an annular seat, wherein the plurality of positioning columns II and the annular seat are arranged at equal angular intervals on the circumference of the ultrasonic probe body, a plurality of circular rings are fixedly connected and mounted on the positioning columns II, the annular seat is rotatably mounted on the circular ring located at the top, the plurality of circular rings located at the bottom are connected to each other via a core seat, and the core seat is fixedly connected to the positioning columns I at the bottom of the ultrasonic probe body; a plurality of clamping edges are arranged on the inner side of the annular seat, a bag is placed between the plurality of clamping edges, and Adenophora adenophora powder is placed in the bag.

[0007] Furthermore, the bag is made of water-permeable materials such as semi-permeable membrane, polypropylene fiber and nylon mesh.

[0008] Furthermore, a plurality of limiting posts are distributed around the bottom circumference of the annular seat, and the circular ring at the top is slidably mounted on the outside of the plurality of limiting posts.

[0009] Furthermore, two limiting edges are provided on the side of the ultrasonic probe body, a rotating cover is rotatably installed between the two limiting edges, a plurality of insertion grooves are provided on the rotating cover, a transmission edge is provided on the inner side of the rotating cover, a transmission ring is installed on the outer side of the annular seat, and the transmission ring and the transmission edge are connected by friction transmission.

[0010] Furthermore, the edge of the transmission ring is inserted into the transmission edge.

[0011] Furthermore, a horizontal column is detachably mounted on the inner side of the circular ring at the bottom, and the lower end of the bag is wound around the horizontal column.

[0012] Furthermore, a slide groove is arranged on one of the clamping edges, a slider is slidably mounted on the slide groove, a side of the slider is connected with an arc-shaped bar, an insertion end is arranged at the end of the arc-shaped bar, and the insertion end is plug-connected with the bag.

[0013] Compared with the prior art, the beneficial effects of the utility model are:

[0014] 1. The cell disruption probe for extracting Adenophora radix polysaccharides in the utility model uses a bag to store Adenophora radix powder, which is confined to the surrounding area of ​​the ultrasonic probe body to prevent the Adenophora radix powder from being deposited in the container; and by periodically rotating the annular seat, the bag and the Adenophora radix powder stored therein are driven to rotate together, so that the Adenophora radix powder at various positions inside the bag can be in close contact with the ultrasonic probe body, so that the ultrasonic probe can exert a uniform and stable effect on the Adenophora radix powder, thereby improving the extraction efficiency of the Adenophora radix polysaccharide components.

[0015] 2. The cell disruption probe for extracting Adenophora radix polysaccharides in the utility model is a bag made of water-permeable materials such as semi-permeable membrane, polypropylene fiber and nylon mesh, so as to effectively intercept Adenophora radix powder. The polysaccharide components dissolved in the solvent can pass through the bag smoothly without subsequent filtration, and the operation is highly convenient.

[0016] 3. In the cell disruption probe for extracting Adenophora radix polysaccharides in the utility model, the upper end of the bag is placed between a plurality of clamping edges, and the lower end of the bag is wrapped around a horizontal column. As the extraction of the polysaccharide components progresses, the annular seat is controlled to continuously rotate in one direction to tighten the bag, thereby further improving the effect of the ultrasonic probe on the Adenophora radix powder. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Other features, objects and advantages of the present application will become more apparent by reading the detailed description of non-limiting embodiments made with reference to the following drawings:

[0018] Figure 1 The overall structure of the cell disruption probe for extracting Adenophora polysaccharide provided in the embodiment of the utility model is shown in FIG. Figure 1 ;

[0019] Figure 2 The overall structure of the cell disruption probe for extracting Adenophora polysaccharide provided in the embodiment of the utility model is shown in FIG. Figure 2 ;

[0020] Figure 3 A schematic diagram of the structure of a cell disruption probe for extracting Adenophora adenophora polysaccharides provided in an embodiment of the utility model;

[0021] Figure 4 This is a cross-sectional view of the ultrasonic probe body and the rotating cover provided in the embodiment of the utility model.

[0022] In the figure: 11 ultrasonic probe body, 12 positioning column I, 13 limiting edge, 14 sealing end, 21 rotating cover, 22 transmission edge, 23 insertion groove, 31 positioning column II, 32 circular ring, 321 horizontal column, 33 core seat, 34 annular seat, 341 clamping edge, 342 sliding groove, 35 limiting column, 36 slider, 361 insertion end, 362 arc strip, 37 transmission ring. DETAILED DESCRIPTION

[0023] The technical solution of the present utility model will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present utility model, rather than all of the embodiments.

[0024] The components of the embodiments of the present invention generally described and shown in the drawings herein can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention.

[0025] Based on the embodiments of the present utility model, all other embodiments obtained by ordinary technicians in the field without making any creative work shall fall within the scope of protection of the present utility model.

[0026] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0027] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. It should also be noted that, for ease of description, only the parts related to the utility model are shown in the drawings.

[0029] Embodiment 1:

[0030] like Figure 1 and Figure 3 As shown, the present embodiment provides a cell disruption probe for extracting Adenophora polysaccharide, comprising an ultrasonic probe body 11, a plurality of positioning columns II 31 and an annular seat 34; a sealing end 14 is installed on the outer side of the top of the ultrasonic probe body 11, and the outer wall of the sealing end 14 abuts against the inner wall of the container opening, and a plurality of positioning columns II 31 and annular seat 34 are arranged at equal angles on the circumference of the ultrasonic probe body 11, and a plurality of circular rings 32 are fixedly connected and installed on the positioning columns II 31, and the annular seat 34 is rotatably installed on the circular ring 32 located at the top, and the plurality of circular rings 32 located at the bottom are connected to each other through a core seat 33, and the core seat 33 is fixedly connected to the positioning columns I 12 at the bottom of the ultrasonic probe body 11; a plurality of clamping edges 341 are arranged on the inner side of the annular seat 34, and a bag is placed between the plurality of clamping edges 341, and Adenophora powder is placed in the bag;

[0031] The bag is made of water-permeable materials, such as semi-permeable membranes, polypropylene fibers and nylon meshes, so as to effectively intercept the Adenophora radix powder. The polysaccharide components dissolved in the solvent can smoothly pass through the bag without the need for subsequent filtration, and the operation is highly convenient.

[0032] The ultrasonic probe body 11 may be a liquid immersion ultrasonic probe available on the market.

[0033] like Figure 3 As shown, a plurality of limiting posts 35 are distributed around the bottom circumference of the annular seat 34 , and the circular ring 32 at the top is slidably mounted on the outer sides of the plurality of limiting posts 35 .

[0034] When using the cell disruption probe for extracting Adenophora radix polysaccharides of the present application;

[0035] First, a bag is used to store the Adenophora radix powder, and the bag is installed between the multiple clamping edges 341; the ultrasonic probe body 11 is started, and the ultrasonic probe body 11 and the multiple annular seats 34 are immersed under the solvent liquid surface. Under the action of the bag, the Adenophora radix powder is confined to the surrounding area of ​​the ultrasonic probe body 11 to prevent the Adenophora radix powder from being deposited in the container;

[0036] Afterwards, after the ultrasonic probe body 11 has been working for a period of time, the ultrasonic probe body 11 is periodically pulled out and the annular seat 34 is rotated, driving the bag and the Adenophora radix powder contained therein to rotate together, so that the Adenophora radix powder at various positions inside the bag can be in close contact with the ultrasonic probe body 11, allowing the ultrasonic probe to exert a uniform and stable effect on the Adenophora radix powder, thereby improving the extraction efficiency of the Adenophora radix polysaccharide components.

[0037] Since the annular seat 34 is directly connected to the side of the ultrasonic probe body 11 , it is easy to extract the multiple bags and the ultrasonic probe body 11 from the solvent together.

[0038] In order to improve the clamping stability of the bag by the multiple clamping edges 341, as Figure 3 As shown, a slide groove 342 is provided on one of the clamping edges 341, a slider 36 is slidably installed on the slide groove 342, a curved strip 362 is connected to the side of the slider 36, an insertion end 361 is provided at the end of the curved strip 362, and the insertion end 361 is plug-connected to the bag to stably clamp the bag.

[0039] In order to further improve the extraction efficiency of Adenophora polysaccharides, Figure 2 As shown, a cross column 321 is detachably mounted on the inner side of the circular ring 32 at the bottom by means of fasteners, so that the upper end of the bag is placed between a plurality of clamping edges 341, and the lower end of the bag is wrapped around the cross column 321; along with the extraction process of the polysaccharide component, the annular seat 34 is controlled to continuously rotate in one direction to tighten the bag, thereby further improving the effect of the ultrasonic probe applied to the Adenophora dasyphylla powder.

[0040] Embodiment 2:

[0041] The features of this embodiment that are the same as those of the first embodiment are not described in detail. The difference between this embodiment and the first embodiment is that: Figure 1-2 and Figure 4 As shown, in this embodiment, two limit edges 13 are provided on the side of the ultrasonic probe body 11, a rotating cover 21 is rotatably installed between the two limit edges 13, a plurality of insertion grooves 23 are provided on the rotating cover 21, a transmission edge 22 is provided on the inner side of the rotating cover 21, a transmission ring 37 is installed on the outer side of the annular seat 34, and the transmission ring 37 is connected to the transmission edge 22 by friction transmission; the ultrasonic probe body 11 is manually rotated, and the plurality of annular seats 34 are synchronously rotated and controlled.

[0042] The edge of the transmission ring 37 is inserted into the transmission edge 22, which can make the annular seat 34 rotate more smoothly and avoid damage to the ultrasonic probe body 11 in the equipment due to mechanical effects.

[0043] The above description is only a preferred embodiment of the present application and an explanation of the technical principles used. Those skilled in the art should understand that the scope of the utility model involved in the present application is not limited to the technical solution formed by a specific combination of the above technical features, but should also cover other technical solutions formed by any combination of the above technical features or their equivalent features without departing from the concept of the utility model. For example, the above features are replaced with the technical features with similar functions disclosed in the present application (but not limited to) by each other to form a technical solution.

[0044] Except for the technical features described in the specification, the other technical features are known technologies to those skilled in the art. In order to highlight the innovative features of the present utility model, the other technical features will not be described in detail here.

Claims

1. A cell disruption probe for extracting Adenophora radix polysaccharides, comprising an ultrasonic probe body (11), characterized in that: The side of the ultrasonic probe body (11) is provided with a plurality of positioning columns II (31) and an annular seat (34); a plurality of circular rings (32) are fixedly connected and mounted on the positioning column II (31); the annular seat (34) is rotatably mounted on the circular ring (32) at the top; the plurality of circular rings (32) at the bottom are connected to each other via a core seat (33); and the core seat (33) is fixedly connected to the positioning column I (12) at the bottom of the ultrasonic probe body (11); A plurality of clamping edges (341) are arranged on the inner side of the annular seat (34), and a bag made of a water-permeable material is placed between the plurality of clamping edges (341), wherein Adenophora radix powder is placed in the bag.

2. The cell disruption probe for extracting Adenophora radix polysaccharides according to claim 1, characterized in that: A plurality of limiting posts (35) are distributed around the bottom circumference of the annular seat (34), and the circular ring (32) at the top is slidably mounted on the outside of the plurality of limiting posts (35).

3. The cell disruption probe for extracting Adenophora radix polysaccharides according to claim 1, characterized in that: Two limiting edges (13) are arranged on the side of the ultrasonic probe body (11); a rotating cover (21) is rotatably mounted between the two limiting edges (13); a plurality of insertion grooves (23) are arranged on the rotating cover (21); a transmission edge (22) is arranged on the inner side of the rotating cover (21); a transmission ring (37) is installed on the outer side of the annular seat (34); and the transmission ring (37) is connected to the transmission edge (22) through friction transmission.

4. The cell disruption probe for extracting Adenophora radix polysaccharides according to claim 3, characterized in that: The edge of the transmission ring (37) is inserted into the transmission edge (22).

5. The cell disruption probe for extracting Adenophora radix polysaccharides according to claim 1, characterized in that: A horizontal column (321) is detachably mounted on the inner side of the circular ring (32) at the bottom, and the lower end of the bag is wound around the horizontal column (321).

6. The cell disruption probe for extracting Adenophora radix polysaccharides according to claim 1, characterized in that: A slide groove (342) is provided on one of the clamping edges (341), a slider (36) is slidably mounted on the slide groove (342), a side of the slider (36) is connected to an arc-shaped strip (362), an end of the arc-shaped strip (362) is provided with an insertion end (361), and the insertion end (361) is plug-connected to the bag.

7. The cell disruption probe for extracting Adenophora radix polysaccharides according to claim 1, characterized in that: A sealing end (14) is installed on the outer side of the top of the ultrasonic probe body (11).