Novel protein marker diagnostic kit for detecting muscle injury degree

By designing a novel protein biomarker diagnostic kit, this method assesses muscle damage using the concentration of specific protein biomarkers in the blood, solving the problem of existing technologies being unable to accurately assess the severity of skeletal muscle damage and achieving rapid and accurate detection results.

CN223471043UActive Publication Date: 2025-10-24THE THIRD HOSPITAL OF HEBEI MEDICAL UNIV
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Patent Information

Application Number
CN202421999297.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-19
Publication Date
2025-10-24
Estimated Expiration
2034-08-19

AI Technical Summary

Technical Problem

Current technologies lack specific indicators for assessing the severity of mechanical skeletal muscle injury, and commonly used enzyme markers are not reliable enough to effectively differentiate the degree of injury.

Method used

A novel protein biomarker diagnostic kit has been designed, comprising a test kit and a dust cover. This kit assesses the degree of muscle damage by detecting the concentration of specific protein biomarkers in the blood. A transparent acrylic dust cover and guide groove structure are used to ensure the accuracy and convenience of the test.

Benefits of technology

It enables rapid and accurate detection of muscle damage, providing a basis for treatment, shortening detection time, and reducing costs.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a novel protein marker diagnostic kit for detecting the muscle injury degree, which comprises a detection kit for detecting the muscle injury degree and a dustproof cover assembled above the detection kit, the detection kit is provided with a detection port for dropping blood of a patient and a display port for displaying a diagnosis result, a reagent card for evaluating the muscle injury degree by detecting the concentration of a specific protein marker in the blood is arranged in the detection kit, and the detection end of the reagent card is located below the detection port. The display end of the reagent card is positioned below the display opening; a positioning opening for positioning the dustproof cover is formed above the detection kit, and a positioning block matched with the positioning opening is arranged in the dustproof cover. According to the utility model, the muscle injury degree of a patient can be detected by quickly reading the novel protein marker in the blood, so that an accurate diagnosis and treatment basis is provided for the treatment of the patient, the detection time of the patient is shortened, and the treatment cost is reduced.
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Description

TECHNICAL FIELD

[0001] The utility model relates to in vitro diagnosis detection technical field more particularly to a novel protein marker diagnostic kit for detecting muscle injury degree. BACKGROUND

[0002] Orthopedic trauma is often accompanied by muscle soft tissue injury, and severe skeletal muscle injury usually leads to incomplete regeneration, resulting in dysfunction. In clinical practice, understanding the degree of skeletal muscle injury in patients with limb trauma is crucial for selecting treatment methods and evaluating prognosis.

[0003] Currently, there is a lack of specific indicators for assessing the severity of mechanical skeletal muscle injury. The existing classic blood protein markers related to muscle tissue decomposition and fiber injury include creatine kinase, lactate dehydrogenase, myoglobin, aldolase, and aspartate aminotransferase, among which creatine kinase is the most commonly used serum marker for muscle injury. However, these established enzymes lack high diagnostic reliability, and they cannot effectively distinguish the severity of injury. SUMMARY

[0004] The technical problem to be solved by the utility model is to provide a novel protein marker diagnostic kit for detecting muscle injury degree, which can quickly detect the degree of muscle injury and provide a basis for treatment.

[0005] To solve the above technical problems, the technical solutions adopted by the utility model are as follows.

[0006] A novel protein marker diagnostic kit for detecting muscle injury degree, comprising a detection kit for detecting muscle injury degree and a dust cover fitted above the detection kit, the detection kit is provided with a detection port for dropping patient blood and a display port for displaying diagnostic results, the detection kit is provided with a reagent card for evaluating muscle injury degree by detecting specific protein marker concentration in blood, the detection end of the reagent card is located below the detection port, and the display end of the reagent card is located below the display port; the upper part of the detection kit is provided with a positioning port for positioning the dust cover, and the inside of the dust cover is provided with a positioning block matched with the positioning port.

[0007] Further optimization of the technical solutions, the two side ends of the detection kit are provided with guide grooves, and the inside of the dust cover is provided with guide protrusions that can slide along the guide grooves.

[0008] Further optimization of the technical solutions, the front end height of the dust cover in the push-pull direction is less than the rear end height, and the positioning block is arranged at the front end in the push-pull direction.

[0009] Further optimization of the technical solutions, the side end of the dust cover is provided with a groove for conveniently removing the dust cover.

[0010] Further optimize technical scheme, the recess is provided with several anti-skid bumps for enhancing friction.

[0011] Further optimize technical scheme, the dust cover is transparent acrylic dust cover.

[0012] Due to the adoption of the above technical scheme, the technical progress achieved by the utility model is as follows.

[0013] The novel protein marker diagnostic kit for detecting muscle injury degree is characterized in that blood of a patient is dropped into the detection port, the muscle injury degree of the patient can be detected through the concentration of specific protein markers in the blood, a basis is provided for treatment of the patient, the detection time of the patient is shortened, and treatment cost is reduced. BRIEF DESCRIPTION OF DRAWINGS

[0014] Fig. 1 It is a structural schematic view of the utility model;

[0015] Fig. 2 It is a side view of the utility model;

[0016] Fig. 3 It is a side view of the detection box;

[0017] Fig. 4 It is an exploded view of the utility model.

[0018] Among them: 1. detection kit, 2. dust cover, 3. detection port, 4. display port, 5. recess, 6. anti-skid bump, 7. positioning port, 8. guide groove, 9. positioning block, 10. guide convex rib. DETAILED DESCRIPTION

[0019] The utility model will be further explained in detail in combination with the drawings and specific embodiments.

[0020] A novel protein marker diagnostic kit for detecting muscle injury degree, in combination with Figs. 1 to 4 As shown in the figure, it comprises a detection kit 1 and a dust cover 2, the detection kit 1 is used for detecting muscle injury degree, and the dust cover 2 is matched with the detection kit 1.

[0021] The detection kit 1 is provided with a detection port 3 and a display port 4, the detection port 3 is used for dropping blood of a patient, the display port 4 is used for displaying a diagnosis result, the inside of the detection kit 1 is provided with a reagent card, the muscle injury degree is evaluated by detecting the concentration of specific protein markers in blood, the detection end of the reagent card is located below the detection port 3, the display end of the reagent card is located below the display port 4, blood is dropped into the detection end of the reagent card through the detection port, the blood sample moves to the display port through capillary action, and finally is displayed through the display end.

[0022] The specific protein marker antibody arranged in the reagent card is one of thirty-seven novel protein markers in the following table, and the novel protein markers have been verified by a large number of clinical samples, and the diagnostic threshold is shown in the following table.

[0023]

[0024]

[0025]

[0026] Two display lines are arranged on the display port 4, one of which is marked with "T" below, and the other is marked with "C" below. The C line is a control line, which is used to ensure the validity of the test, and if the control line develops color, the test is valid; the T line is a test line, which displays the concentration of specific protein markers in blood through the depth of color.

[0027] The detection kit 1 is slidably arranged with the dust cover 2, the upper portion of the detection kit 1 is provided with a positioning port 7, the inside of the dust cover 2 is provided with a positioning block 9, the positioning block 9 is matched with the positioning port 7, and the positioning block 9 is used to realize the positioning between the detection kit 1 and the dust cover 2, so that the dust cover is prevented from falling off during taking, and dust and impurities in the air pollute the detection port.

[0028] The two side ends of the detection kit 1 are provided with guide grooves 8, and the two sides of the inside of the dust cover 2 are provided with guide convex ribs 10, the guide convex ribs are slidably arranged in the guide grooves, and the dust cover is convenient to take and place.

[0029] The height of the front end of the dust cover 2 in the pushing and pulling direction is less than the height of the rear end, and the positioning block 9 is located at the front end in the pushing and pulling direction, so that the positioning of the dust cover is realized.

[0030] In order to facilitate the detection result, the dust cover 2 is provided as a transparent acrylic dust cover, which has certain strength and will not be damaged when falling, has good optical purity and light transmittance, and can read the result through the reflectance photometer without opening the dust cover.

[0031] The side end of the dust cover 2 is provided with an arc-shaped groove 5, so as to facilitate the removal of the dust cover, and a plurality of anti-skid convex blocks 6 are arranged in the groove 5, so as to enhance the friction.

[0032] When detecting the muscle injury degree of a patient, the dust cover is opened, the blood of the patient is drawn and dropped on the detection port, after the blood permeates on the inside reagent card, the dust cover is pushed forward to cover the detection kit, at this time, the reagent card detects the corresponding novel protein marker in the blood, and after the detection is completed, the display port T line displays the detection result through the color depth.

[0033] During the test, when the control line (C line) is colored, it indicates that the test is effective. After the test line (T line) is colored, the utility model is placed under the reflectance photometer to measure the light intensity reflected by the test line (T line) color bar, and then the muscle injury grade of the patient is determined through the relationship curve of the light intensity value and the concentration of each protein marker and the corresponding relationship between the content of each protein marker and the injury degree, so as to quickly provide the treatment basis.

Claims

1. A novel protein marker diagnostic kit for detecting the degree of muscle injury, characterized by: The application relates to a detection kit (1) for detecting the degree of muscle injury and a dustproof cover (2) matched with the detection kit (1), wherein the detection kit (1) is provided with a detection port (3) for dropping blood of a patient and a display port (4) for displaying a diagnosis result; the detection kit (1) is internally provided with a reagent card for evaluating the degree of muscle injury by detecting the concentration of specific protein markers in the blood; the detection end of the reagent card is located below the detection port (3), and the display end of the reagent card is located below the display port (4); the upper portion of the detection kit (1) is provided with a positioning port (7) for positioning the dustproof cover (2); and the dustproof cover (2) is internally provided with a positioning block (9) matched with the positioning port.

2. The novel protein marker diagnostic kit for detecting the degree of muscle injury according to claim 1, characterized by: The two side ends of the detection kit (1) are provided with guide grooves (8), and the dustproof cover (2) is internally provided with guide convex ribs (10) which can slide along the guide grooves.

3. The novel protein marker diagnostic kit for detecting the degree of muscle injury according to claim 1, characterized by: The front end of the dustproof cover (2) in the push-pull direction is lower than the rear end; and the positioning block (9) is arranged at the front end in the push-pull direction.

4. The novel protein marker diagnostic kit for detecting the degree of muscle injury according to claim 1, characterized by: The side end of the dustproof cover (2) is provided with a groove (5) for facilitating the removal of the dustproof cover.

5. The novel protein marker diagnostic kit for detecting the degree of muscle injury according to claim 4, characterized by: The groove (5) is internally provided with a plurality of anti-skid convex blocks (6) for enhancing friction.

6. The novel protein marker diagnostic kit for detecting the degree of muscle injury according to claim 1, characterized by: The dustproof cover (2) is a transparent acrylic dustproof cover.

Citation Information

Cited By

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