Noninvasive full-flexible skin flap transplantation post-operation multi-index monitoring wearable sensor

Abstract

The utility model discloses a non-invasive full-flexible skin flap transplantation post-operation multi-index monitoring wearable sensor which comprises a sealing cover sensing layer, a skin isolation layer and a sensor assembly arranged between the sealing cover sensing layer and the skin isolation layer. The sensor assembly comprises a strain sensor, a temperature sensor, a humidity sensor and a blood oxygen saturation degree sensor, the sealing cover sensing layer and the skin isolation layer are both made of flexible materials, and the lower layer of the skin isolation layer is used for making contact with the skin of a patient; the strain sensor, the temperature sensor, the humidity sensor and the oxyhemoglobin saturation sensor are respectively used for monitoring swelling, temperature, humidity and oxyhemoglobin saturation of a transplanted flap of a patient. The non-invasive full-flexible skin flap transplantation post-operation multi-index monitoring wearable sensor can non-invasively and continuously detect the swelling, temperature and humidity states of postoperative transplanted skin flaps and the change condition of blood oxygen saturation in real time, and the success rate of skin flap transplantation is increased.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of medical and health products, and particularly relates to a noninvasive full-flexible flap grafting postoperative multi-index monitoring wearable sensor. BACKGROUND

[0002] Skin, as the main barrier to resist harmful environmental factors, plays a key role in protection, sensation, metabolism and body temperature regulation; but due to work trauma, cancer resection, accidental injury or dermatological intervention, human skin is often severely damaged; flap grafting is an effective skin repair method, but abnormal conditions after flap grafting cannot be intervened and treated in time, which brings great challenges to the success of flap grafting.

[0003] Traditional postoperative monitoring methods include lack of standardized clinical examination, and color Doppler ultrasound, near-infrared spectroscopy and other equipment examination methods that cannot realize continuous monitoring and require experienced medical professionals, which cannot simultaneously perform comprehensive and continuous monitoring of multiple indexes; secondly, the gauze bandage in the transplanted flap area brings many limitations to postoperative monitoring, such as hindering real-time observation of the healing process, and in addition, regular removal of the bandage for examination may cause secondary tissue damage; these damages will further lead to postoperative complications such as ischemia, infection and necrosis, and if there is no real-time and continuous monitoring, the best opportunity for early intervention will be missed.

[0004] Using a miniature, flexible and noninvasive sensor to realize real-time and continuous monitoring of the transplanted flap is a suitable method to promote early intervention; with the development of nanotechnology and advanced materials science technology, more and more wearable sensors applied to postoperative monitoring of flap grafting are developed, but there are still deficiencies in the comprehensiveness of the monitoring indexes and the flexibility of the sensors; most of the monitoring devices focus on blood oxygen saturation and temperature monitoring, and cannot realize comprehensive monitoring of multiple indexes, in addition, non-full-flexible devices do not consider the comfort of the patient wearing. UTILITY MODEL CONTENTS

[0005] The utility model solves the technical problems existing in the prior art, provides a noninvasive full-flexible flap grafting postoperative multi-index monitoring wearable sensor, which can noninvasively, real-timely and continuously detect the swelling, temperature, humidity and blood oxygen saturation of the postoperative transplanted flap, and improves the success rate of flap grafting.

[0006] In order to solve the above problems, the utility model adopts the following technical scheme:

[0007] The application discloses a non-invasive full-flexible flap transplantation postoperative multi-index monitoring wearable sensor, which comprises a cover sensing layer, a skin isolation layer and a sensor assembly arranged between the cover sensing layer and the skin isolation layer, wherein the sensor assembly comprises a strain sensor, a temperature sensor, a humidity sensor and a blood oxygen saturation sensor; the cover sensing layer and the skin isolation layer are both made of flexible materials; the lower layer of the skin isolation layer is used for contacting the skin of a patient; the strain sensor, the temperature sensor, the humidity sensor and the blood oxygen saturation sensor are respectively used for monitoring the swelling, temperature, humidity and blood oxygen saturation of the transplanted flap of the patient.

[0008] Preferably, the strain sensor is in a snake shape, the temperature sensor is in a circular ring shape, the humidity sensor is in a gold fork shape, and the blood oxygen saturation sensor adopts a photoplethysmography method for measurement.

[0009] Preferably, a water molecule contact window corresponding in size and shape to the humidity sensor is formed in the skin isolation layer.

[0010] Preferably, the non-invasive full-flexible flap transplantation postoperative multi-index monitoring wearable sensor further comprises a GO solution deposition layer, the GO solution deposition layer is completely identical in size and shape to the water molecule contact window and is embedded in the water molecule contact window, and the bottom of the humidity sensor is completely attached to the GO solution deposition layer.

[0011] Preferably, the materials of the cover sensing layer and the skin isolation layer are both PDMS films.

[0012] Preferably, the blood oxygen saturation sensor comprises a light emitter and a photoelectric detector; the light emitter is used for emitting 660-nanometer red light and 940-nanometer near-infrared light to irradiate hemoglobin and deoxyhemoglobin in blood; and the photoelectric detector captures the reflected light and reflects the change of blood oxygen saturation through the intensity change of the light.

[0013] Preferably, the strain sensor, the temperature sensor and the humidity sensor are all made of laser-induced graphene-based materials.

[0014] The non-invasive full-flexible flap transplantation postoperative multi-index monitoring wearable sensor in the application is provided with the sensor assembly comprising the strain sensor, the temperature sensor, the humidity sensor and the blood oxygen saturation sensor, so that the swelling, temperature, humidity state and blood oxygen saturation change of the postoperative transplanted flap can be non-invasively, real-timely and continuously detected, strong evidence is provided for doctors to timely perform postoperative early intervention, and the success rate of flap transplantation is improved. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1This is an exploded view of the wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation in Embodiment 1 of this utility model;

[0016] Figure 2 This is a bottom view of the sealing sensing layer in Embodiment 1 of this utility model;

[0017] Figure 3 This is a schematic diagram of the skin isolation layer in Embodiment 1 of this utility model;

[0018] Figure 4 This is a schematic diagram of the GO solution deposition layer in Embodiment 1 of this utility model.

[0019] In the figure: 11-Strain sensor, 12-Temperature sensor, 13-Humidity sensor, 14-Blood oxygen saturation sensor, 15-Sealing sensing layer, 21-Skin isolation layer, 22-Water molecule contact window, 23-GO solution deposition layer. Detailed Implementation

[0020] The technical solutions of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of this utility model.

[0021] In the description of this utility model, it should be noted that the terms "above" and other indications of orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience and simplification of description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0022] In the description of this utility model, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0023] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "connection," "setting," "installation," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0024] This invention provides a non-invasive, fully flexible skin flap transplantation postoperative multi-index monitoring wearable sensor, including a capping sensing layer, a skin isolation layer, and a sensor assembly disposed between the capping sensing layer and the skin isolation layer. The sensor assembly includes a strain sensor, a temperature sensor, a humidity sensor, and a blood oxygen saturation sensor. Both the capping sensing layer and the skin isolation layer are made of flexible materials. The lower layer of the skin isolation layer is for contact with the patient's skin. The strain sensor, temperature sensor, humidity sensor, and blood oxygen saturation sensor are used to monitor the swelling, temperature, humidity, and blood oxygen saturation of the transplanted skin flap, respectively.

[0025] Example 1

[0026] like Figure 1 As shown, this embodiment discloses a non-invasive, fully flexible flap transplantation postoperative multi-index monitoring wearable sensor, including a capping sensing layer 15, a skin isolation layer 21, and a sensor assembly disposed between the capping sensing layer 15 and the skin isolation layer 21.

[0027] In this embodiment, the sensor assembly includes a strain sensor 11, a temperature sensor 12, a humidity sensor 13, and a blood oxygen saturation sensor 14. Both the sealing sensing layer 15 and the skin isolation layer 21 are made of flexible materials, with the lower layer of the skin isolation layer 21 designed for contact with the patient's skin. The strain sensor 11, temperature sensor 12, humidity sensor 13, and blood oxygen saturation sensor 14 are used to monitor the swelling, temperature, humidity, and blood oxygen saturation of the transplanted skin flap, respectively. This enables non-invasive, real-time, and continuous monitoring of the postoperative swelling, temperature, humidity, and blood oxygen saturation changes of the transplanted skin flap, providing strong evidence for timely early postoperative intervention and improving the success rate of skin flap transplantation.

[0028] Specifically, the sealing sensing layer 15 serves as the substrate for the strain sensor 11, temperature sensor 12, humidity sensor 13, and blood oxygen saturation sensor 14, meaning that the sensor assembly is fixed to the bottom of the sealing sensing layer 15.

[0029] In this embodiment, wearable sensors are used to monitor patients with transplanted skin flaps. The sensor assembly is used to sense the recovery status of the transplanted skin flap.

[0030] Specifically, strain sensor 11 senses changes in swelling of the transplanted skin flap, temperature sensor 12 senses changes in temperature of the transplanted skin flap, humidity sensor 13 senses changes in humidity of the transplanted skin flap, and blood oxygen saturation sensor 14 senses changes in blood oxygen saturation of the transplanted skin flap, thereby achieving real-time and comprehensive monitoring of the postoperative recovery of the skin flap and enabling timely early intervention of the transplanted skin flap.

[0031] Since changes in blood oxygen saturation are the earliest sign of vascular damage, swelling parameters are physical indicators of postoperative inflammation, temperature changes can indicate potential infection or changes in blood flow, and maintaining an appropriate humidity environment can improve wound healing rate; these four indicators comprehensively reflect the patient's postoperative recovery and provide strong evidence for doctors to intervene in the early postoperative period in a timely manner, thereby improving the success rate of flap transplantation.

[0032] like Figure 1 , 2 As shown, specifically, the temperature sensor 12 is circular and located in the middle, while the strain sensor 11, humidity sensor 13, and blood oxygen saturation sensor 14 are arranged around the temperature sensor 12.

[0033] The strain sensor 11 is serpentine in shape. This serpentine shape effectively increases the resistance value of the strain sensor 11, resulting in smaller resistance fluctuations during measurement compared to the actual resistance value of the strain sensor 11. This, in turn, increases the upper and lower limits of its measurement, thus providing a larger measurement range. The humidity sensor 13 is in the shape of a gold forked finger, and the blood oxygen saturation sensor 14 uses photoplethysmography for measurement.

[0034] like Figure 1 , 3 As shown, a water molecule contact window 22 corresponding to the shape and size of the humidity sensor 13 is provided on the skin isolation layer 21, and the position of the water molecule contact window 22 corresponds to the position of the humidity sensor 13, thereby providing a reaction space for the humidity sensor 13 to take effect, which is beneficial for the humidity sensor 13 to sense the humidity of the transplanted skin flap.

[0035] like Figure 4 As shown, furthermore, the wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation also includes a GO solution deposition layer 23. The size and shape of the GO solution deposition layer 23 are exactly the same as those of the water molecule contact window 22, and it is embedded within the water molecule contact window 22. The bottom of the humidity sensor 13 is completely attached to the GO solution deposition layer 23. The function of the GO solution deposition layer 23 is to utilize the hydrophilicity of the GO solution to make the humidity sensor 13 more sensitive to water molecules in a humid environment, thereby improving the humidity response.

[0036] Optionally, both the sealing sensing layer 15 and the skin isolation layer 21 are made of PDMS film. Specifically, the PDMS film is made of polydimethylsiloxane (PDMS) and has good flexibility. The skin isolation layer 21 contacts the patient's skin, effectively improving the patient's comfort when wearing the sensor, conforming to the skin, adapting to various skin flap scenarios, and minimizing patient discomfort.

[0037] The sealing sensing layer 15 can prevent water molecules in the environment from affecting the detection of the humidity sensor 13. At the same time, the sealing sensing layer 15 can also prevent external friction from damaging the strain sensor 11, temperature sensor 12, and humidity sensor 13. Furthermore, the sealing sensing layer 15 also serves as the base layer for the wires of the blood oxygen saturation sensor 14.

[0038] In this embodiment, photoplethysmography is a non-invasive physiological monitoring technology based on optical principles. Photoplethysmography uses the absorption, reflection and transmission properties of light to monitor the dynamic changes of blood as it passes through the skin and blood vessels, and calculates blood oxygen saturation using the voltage information collected by the blood oxygen saturation sensor 14.

[0039] Specifically, the blood oxygen saturation sensor 14 includes a light emitter and a photodetector. The light emitter emits 660 nm red light and 940 nm near-infrared light to irradiate hemoglobin and deoxyhemoglobin in the blood. The photodetector captures the reflected light and reacts to changes in blood oxygen saturation by changes in light intensity. The relationship between changes in light intensity and changes in blood oxygen saturation follows Beer-Lambert's law.

[0040] Optionally, the strain sensor 11, temperature sensor 12, and humidity sensor 13 are all made of laser-induced graphene-based material. Specifically, the laser-induced graphene-based strain sensor 11, temperature sensor 12, and humidity sensor 13 are transferred from the PI film substrate to the PDMS thin film (capped sensing layer 15) substrate via a transfer method; the blood oxygen saturation sensor 14 has its circuitry directly soldered onto the PDMS thin film (capped sensing layer 15).

[0041] The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation in this embodiment includes a strain sensor 11, a temperature sensor 12, a humidity sensor 13, and a blood oxygen saturation sensor 14. This enables non-invasive, real-time, and continuous monitoring of the swelling, temperature, humidity, and blood oxygen saturation of the transplanted flap after surgery. This provides strong evidence for timely early postoperative intervention by physicians, improving the success rate of flap transplantation. Furthermore, the skin isolation layer 21 is made of PDMS film, which has excellent flexibility, effectively improving patient comfort when wearing the sensor. It conforms to the skin, adapts to various flap scenarios, and minimizes patient discomfort.

[0042] It is understood that the above embodiments are merely exemplary implementations used to illustrate the principles of this utility model, and the utility model is not limited thereto. For those skilled in the art, various modifications and improvements can be made without departing from the spirit and essence of this utility model, and these modifications and improvements are also considered to be within the protection scope of this utility model.

Claims

1. A wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation, characterized in that, It includes a capping sensing layer (15), a skin barrier layer (21), and a sensor assembly disposed between the capping sensing layer (15) and the skin barrier layer (21). The sensor assembly includes a strain sensor (11), a temperature sensor (12), a humidity sensor (13), and a blood oxygen saturation sensor (14). Both the sealing sensing layer (15) and the skin barrier layer (21) are made of flexible material. The lower layer of the skin barrier layer (21) is designed for contact with the patient's skin. The strain sensor (11), temperature sensor (12), humidity sensor (13), and blood oxygen saturation sensor (14) are used to monitor the swelling, temperature, humidity, and blood oxygen saturation of the transplanted skin flap in the patient, respectively.

2. The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation according to claim 1, characterized in that, The strain sensor (11) is serpentine, the temperature sensor (12) is annular, and the humidity sensor (13) is forked. The blood oxygen saturation sensor (14) is measured using photoplethysmography.

3. The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation according to claim 2, characterized in that, The skin barrier layer (21) has a water molecule contact window (22) that corresponds to the shape and size of the humidity sensor (13).

4. The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation according to claim 3, characterized in that, It also includes a GO solution deposition layer (23), the size and shape of which are exactly the same as the water molecule contact window (22) and are embedded in the water molecule contact window (22), and the bottom of the humidity sensor (13) is completely attached to the GO solution deposition layer (23).

5. The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation according to claim 1, characterized in that, The materials of the sealing sensing layer (15) and the skin isolation layer (21) are both PDMS films.

6. The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation according to claim 2, characterized in that, The blood oxygen saturation sensor (14) includes a light emitter and a photodetector. The light emitter is used to emit 660 nm red light and 940 nm near-infrared light to irradiate hemoglobin and deoxyhemoglobin in the blood. The photodetector captures the reflected light and uses changes in light intensity to reflect changes in blood oxygen saturation.

7. The wearable sensor for multi-index monitoring after non-invasive, fully flexible flap transplantation according to any one of claims 1-6, characterized in that, The strain sensor (11), the temperature sensor (12), and the humidity sensor (13) are all made of laser-induced graphene-based material.

Images