Pharmaceutical low-temperature sampling anti-pollution clamp
Patent Information
- Application Number
- CN202521973886.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-15
- Publication Date
- 2026-09-04
- Estimated Expiration
- 2035-09-15
AI Technical Summary
[0005]本实用新型提供了一种制药低温取样防污染夹具,具备便于在取样时保持稳定并有效防止样品与外界环境接触的优点,以解决现有的制药低温取样防污染夹具,在使用过程中,难以在取样时难以保持稳定,且无法有效防止样品与外界环境接触,导致样本在取样过程中易受污染的问题
该制药低温取样防污染夹具,通过夹持组件的设置,在使用时,将防护套筒对准制药罐上的外接管插入,进而启动液压推动杆推动滑动套筒在防护套筒的内部滑动,并深入制药罐内,进而启动伸缩气缸,使得伸缩气缸推动推块,进而弯杆的两端分别在推块和转动座上转动,由于固定块位置不变,使得转动座带动夹片对制药样品瓶进行夹持,从而防止取样时瓶身晃动或滑脱,确保取样位置和深度的准确性,同时减少人工干预,降低污染风险。
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Figure CN224719676U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of clamp technology, specifically a pharmaceutical low-temperature sampling anti-contamination clamp. Background Technology
[0002] In the pharmaceutical industry, cryogenic sampling anti-contamination clamps are mainly used to ensure that samples are not contaminated during drug production and research and development. Such clamps are crucial in drug quality control and analytical testing. The clamps need to have excellent sealing performance to prevent samples from coming into contact with the external environment during sampling, preventing contamination from microorganisms, dust, chemicals, etc. During drug development, samples are taken from experimental containers or frozen storage to avoid sample contamination.
[0003] Utility model patent CN218725396U discloses a sampling fixture, including a telescopic column that can be raised and lowered by inserting into the inner wall of a limiting column and a connecting column that is inserted into the inner wall of a sliding groove. A support spring is fixedly connected to the upper end of the telescopic column, and a fixed circular plate is fixedly connected to one end of the connecting column. An anti-slip pad is fixedly connected to the outer surface of the circular plate, and a rotatable clamping plate is sleeved on the outer surface of the connecting column. This sampling fixture, through the arrangement of the sliding groove, connecting column, circular plate, anti-slip pad, and clamping plate, allows the user to insert the connecting column into the inner wall of the sliding groove and move it up and down. The clamping plate can rotate, and the circular plate can then be clamped and fixed, improving the user's work efficiency. Furthermore, the telescopic column, limiting column, and spring allow the user to insert the telescopic column into the upper end of the limiting column and adjust it according to their needs.
[0004] However, existing pharmaceutical low-temperature sampling anti-contamination clamps are difficult to maintain stability during sampling and cannot effectively prevent samples from coming into contact with the external environment, making samples susceptible to contamination during the sampling process. Utility Model Content
[0005] This invention provides a pharmaceutical low-temperature sampling anti-contamination clamp, which has the advantages of being easy to maintain stability during sampling and effectively preventing the sample from contacting the external environment. This solves the problem that existing pharmaceutical low-temperature sampling anti-contamination clamps are difficult to maintain stability during sampling and cannot effectively prevent the sample from contacting the external environment, resulting in the sample being easily contaminated during the sampling process.
[0006] To facilitate stable sampling and effectively prevent sample contact with the external environment, this utility model provides the following technical solution: a pharmaceutical low-temperature sampling anti-contamination clamp, comprising a protective sleeve and a sliding sleeve disposed inside the protective sleeve, wherein a fixed frame is fixedly connected to one side of the sliding sleeve, and further comprising: a telescopic cylinder disposed on one side of the fixed frame, wherein a clamping assembly is fixedly connected to one end of the telescopic cylinder, the clamping assembly comprising a push block, a bent rod, a rotating seat and a clamping plate; a positioning assembly disposed at one end of the protective sleeve, wherein the positioning assembly comprises a fixed sleeve and a positioning rod, wherein a positioning ring is inserted into one end of the positioning rod; an outer tube is sleeved inside the positioning ring, and a sealing assembly is slidably connected to the top of the outer tube and the protective sleeve, wherein the sealing assembly comprises a baffle and a handle.
[0007] As a preferred embodiment of the present invention, the clamping assembly includes a push block fixedly connected to one end of a telescopic cylinder. Two sets of bent rods are rotatably connected inside the push block. One end of each bent rod is rotatably connected to a rotating seat, and one end of the rotating seat is fixedly connected to a clamping piece.
[0008] As a preferred embodiment of this utility model, the positioning component includes a fixed sleeve disposed at one end of the protective sleeve, and four sets of positioning rods are fixedly connected to one side of the fixed sleeve.
[0009] As a preferred embodiment of the present invention, the sealing component includes a baffle that is slidably connected to the top of the protective sleeve, and a handle is fixedly connected to the top surface of the baffle.
[0010] As a preferred embodiment of this utility model, one end of the rotating seat is rotatably connected to a fixing block, and the fixing block is fixedly connected to the inner wall of the fixing frame.
[0011] As a preferred embodiment of this utility model, a hydraulic push rod is fixedly connected to one side of the sliding sleeve, and the hydraulic push rod is sleeved on one end of the protective sleeve.
[0012] As a preferred technical solution of this utility model, the top surface of the protective sleeve is fixedly connected with a handle, and the top of both the outer pipe and the protective sleeve are provided with a sliding groove adapted to the baffle.
[0013] As a preferred embodiment of this utility model, the surface of the protective sleeve is provided with a controller, and the surface of the positioning ring is provided with an insertion hole that is compatible with the positioning rod.
[0014] Compared with the prior art, this utility model provides a pharmaceutical low-temperature sampling anti-contamination clamp, which has the following beneficial effects: This pharmaceutical low-temperature sampling anti-contamination clamp, through the design of its clamping components, works by aligning the protective sleeve with the outer connecting pipe on the pharmaceutical container and inserting it. Then, a hydraulic push rod is activated, pushing the sliding sleeve inside the protective sleeve and extending it into the pharmaceutical container. This activates a telescopic cylinder, which pushes a push block. The two ends of the bent rod then rotate on the push block and a rotating seat, respectively. Since the fixed block remains in place, the rotating seat drives the clamping plates to hold the pharmaceutical sample bottle, preventing the bottle from shaking or slipping during sampling. This ensures the accuracy of the sampling position and depth, while reducing manual intervention and lowering the risk of contamination.
[0015] This pharmaceutical low-temperature sampling anti-contamination clamp, through the design of a protective sleeve, positioning components, and sealing components, allows for smooth docking of the protective sleeve and outer tube by inserting the positioning rod into the insertion hole on the positioning ring during use. Then, by pulling the baffle with the handle, the protective sleeve and outer tube are connected for sampling. After sampling, the baffle is reinserted to seal the connection, thereby significantly reducing the risk of external contamination. It also simplifies the docking process and reduces operation time, making it suitable for scenarios with stringent requirements for sample purity, such as biopharmaceuticals and sterile preparations. Attached Figure Description
[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a schematic diagram of the disassembled structure of this utility model; Figure 3 This is a schematic diagram of the clamping component structure of this utility model; Figure 4 This is a schematic diagram of the positioning component and the sealing component of this utility model.
[0017] In the diagram: 1. Protective sleeve; 2. Sliding sleeve; 3. Fixing frame; 4. Telescopic cylinder; 5. Clamping assembly; 501. Push block; 502. Bent rod; 503. Rotating seat; 504. Clamping piece; 6. Positioning assembly; 601. Fixing sleeve; 602. Positioning rod; 7. Positioning ring; 8. Outer connecting pipe; 9. Sealing assembly; 901. Baffle; 902. Handle; 10. Fixing block; 11. Hydraulic push rod; 12. Handle; 13. Controller. Detailed Implementation
[0018] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0019] Please see Figures 1-4This utility model discloses a pharmaceutical low-temperature sampling anti-contamination clamp, including a protective sleeve 1 and a sliding sleeve 2 disposed inside the protective sleeve 1. A fixed frame 3 is fixedly connected to one side of the sliding sleeve 2. The clamp also includes: a telescopic cylinder 4 disposed on one side of the fixed frame 3, with a clamping assembly 5 fixedly connected to one end of the telescopic cylinder 4. The clamping assembly 5 includes a push block 501, a bent rod 502, a rotating seat 503, and a clamping piece 504; a positioning assembly 6 disposed at one end of the protective sleeve 1, including a fixed sleeve 601 and a positioning rod 602, with a positioning ring 7 inserted into one end of the positioning rod 602; an outer tube 8 sleeved inside the positioning ring 7, and a sealing assembly 9 slidably connected to both the outer tube 8 and the top of the protective sleeve 1. The sealing assembly 9 includes a baffle 901 and a handle 902.
[0020] Specifically, the clamping assembly 5 includes a push block 501 fixedly connected to one end of the telescopic cylinder 4. Two sets of bent rods 502 are rotatably connected inside the push block 501. One end of the bent rod 502 is rotatably connected to a rotating seat 503. One end of the rotating seat 503 is fixedly connected to a clamping piece 504.
[0021] In this embodiment, during use, the protective sleeve 1 is inserted into the outer connecting pipe 8 on the pharmaceutical container, and then the hydraulic push rod 11 is activated to push the sliding sleeve 2 to slide inside the protective sleeve 1 and penetrate into the pharmaceutical container. Then the telescopic cylinder 4 is activated, which pushes the push block 501. Then the two ends of the bent rod 502 rotate on the push block 501 and the rotating seat 503 respectively. Since the position of the fixed block 10 remains unchanged, the rotating seat 503 drives the clamping plate 504 to clamp the pharmaceutical sample bottle.
[0022] Specifically, the positioning component 6 includes a fixed sleeve 601 disposed at one end of the protective sleeve 1, and four sets of positioning rods 602 are fixedly connected to one side of the fixed sleeve 601.
[0023] In this embodiment, during use, the positioning rod 602 is inserted into the insertion hole on the positioning ring 7 to ensure a smooth connection between the protective sleeve 1 and the outer pipe 8.
[0024] Specifically, the enclosure component 9 includes a baffle 901 slidably connected to the top of the protective sleeve 1, and a handle 902 is fixedly connected to the top surface of the baffle 901.
[0025] In this embodiment, the baffle 901 is pulled by the handle 902 to make the protective sleeve 1 and the outer pipe 8 connected and to carry out the sampling operation. After the sampling is completed, the baffle 901 is reinserted and sealed.
[0026] Specifically, a fixing block 10 is rotatably connected to one end of the rotating seat 503, and the fixing block 10 is fixedly connected to the inner wall of the fixing frame 3.
[0027] In this embodiment, the rotating seat 503 is connected to the inner wall of the fixed frame 3 through the fixed block 10 to form a stable rotation fulcrum; the rigid connection of the fixed block 10 enhances the torsional resistance of the overall structure and is suitable for high-frequency operation in low-temperature environments.
[0028] Specifically, a hydraulic push rod 11 is fixedly connected to one side of the sliding sleeve 2, and the hydraulic push rod 11 is sleeved on one end of the protective sleeve 1.
[0029] In this embodiment, the hydraulic push rod 11 is linked with the sliding sleeve 2 to provide a smooth axial thrust.
[0030] Specifically, the top surface of the protective sleeve 1 is fixedly connected to a handle 12, and the top of both the outer pipe 8 and the protective sleeve 1 are provided with a sliding groove that matches the baffle 901.
[0031] In this embodiment, the handle 12 facilitates the manual operation of the protective sleeve 1 to move or rotate, while the slide groove ensures smooth linear sliding of the baffle 901, enabling rapid opening and closing of the channel and preventing external contaminants from entering during sampling.
[0032] Specifically, the surface of the protective sleeve 1 is provided with a controller 13, and the surface of the positioning ring 7 is provided with an insertion hole that is compatible with the positioning rod 602.
[0033] In this embodiment, the controller 13 is integrated into the surface of the protective sleeve 1. It can programmably control the coordinated action of the telescopic cylinder 4 and the hydraulic push rod 11 to improve the level of automation. The precise matching of the positioning rod 602 with the insertion hole enables rapid positioning and ensures the sealed connection between the outer pipe 8 and the protective sleeve 1.
[0034] The working principle and usage process of this utility model are as follows: In use, the protective sleeve 1 is inserted into the outer tube 8 on the pharmaceutical container. Then, the hydraulic push rod 11 is activated to push the sliding sleeve 2 to slide inside the protective sleeve 1 and penetrate into the pharmaceutical container. Then, the telescopic cylinder 4 is activated, which pushes the push block 501. Then, the two ends of the bent rod 502 rotate on the push block 501 and the rotating seat 503 respectively. Since the position of the fixed block 10 remains unchanged, the rotating seat 503 drives the clamping plate 504 to clamp the pharmaceutical sample bottle. In use, the positioning rod 602 is inserted into the insertion hole on the positioning ring 7 to make the protective sleeve 1 and the outer tube 8 smoothly connected. Then, the baffle 901 is pulled by the handle 902 to make the protective sleeve 1 and the outer tube 8 connected and to carry out the sampling operation. After the sampling is completed, the baffle 901 is reinserted to close the container.
[0035] In summary, this pharmaceutical low-temperature sampling anti-contamination clamp, through the setting of clamping component 5, prevents the bottle from shaking or slipping during sampling, ensuring the accuracy of sampling position and depth, while reducing manual intervention and lowering the risk of contamination. Through the setting of protective sleeve 1, positioning component 6 and sealing component 9, it achieves the effect of significantly reducing the risk of external contamination, while simplifying the docking process and reducing operation time. It is suitable for scenarios with strict requirements for sample purity, such as biopharmaceuticals and sterile preparations.
[0036] It should be noted that, in this document, terms such as "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.
[0037] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A pharmaceutical low-temperature sampling anti-contamination clamp, comprising a protective sleeve (1) and a sliding sleeve (2) disposed inside the protective sleeve (1), wherein a fixing frame (3) is fixedly connected to one side of the sliding sleeve (2), characterized in that, Also includes: A telescopic cylinder (4) is set on one side of the fixed frame (3). One end of the telescopic cylinder (4) is fixedly connected to a clamping assembly (5). The clamping assembly (5) includes a push block (501), a bent rod (502), a rotating seat (503), and a clamping plate (504). A positioning component (6) is provided at one end of the protective sleeve (1). The positioning component (6) includes a fixed sleeve (601) and a positioning rod (602). A positioning ring (7) is inserted into one end of the positioning rod (602). An outer tube (8) is fitted inside the positioning ring (7). The top of the outer tube (8) and the protective sleeve (1) are slidably connected to a sealing component (9). The sealing component (9) includes a baffle (901) and a handle (902).
2. The pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: The clamping assembly (5) includes a push block (501) fixedly connected to one end of the telescopic cylinder (4). Two sets of bent rods (502) are rotatably connected inside the push block (501). One end of the bent rod (502) is rotatably connected to a rotating seat (503). One end of the rotating seat (503) is fixedly connected to a clamping piece (504).
3. The pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: The positioning component (6) includes a fixed sleeve (601) disposed at one end of the protective sleeve (1), and four sets of positioning rods (602) are fixedly connected to one side of the fixed sleeve (601).
4. The pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: The enclosure component (9) includes a baffle (901) slidably connected to the top of the protective sleeve (1), and a handle (902) is fixedly connected to the top surface of the baffle (901).
5. The pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: One end of the rotating seat (503) is rotatably connected to a fixing block (10), and the fixing block (10) is fixedly connected to the inner wall of the fixing frame (3).
6. The pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: A hydraulic push rod (11) is fixedly connected to one side of the sliding sleeve (2), and the hydraulic push rod (11) is sleeved on one end of the protective sleeve (1).
7. A pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: The top surface of the protective sleeve (1) is fixedly connected to a handle (12), and the top of both the outer pipe (8) and the protective sleeve (1) are provided with a sliding groove that is compatible with the baffle (901).
8. The pharmaceutical low-temperature sampling anti-contamination clamp according to claim 1, characterized in that: The protective sleeve (1) is provided with a controller (13) on its surface, and the positioning ring (7) is provided with a socket that is compatible with the positioning rod (602) on its surface.